| Year |
Citation |
Score |
| 2019 |
Elsaidi HR, Yang XH, Ahmadi F, Weinfeld M, Wiebe LI, Kumar P. Putative electron-affinic radiosensitizers and markers of hypoxic tissue: Synthesis and preliminary in vitro biological characterization of C3-amino-substituted benzotriazine dioxides (BTDOs). European Journal of Medicinal Chemistry. 165: 216-224. PMID 30684798 DOI: 10.1016/J.Ejmech.2019.01.009 |
0.32 |
|
| 2018 |
Sun W, Falzon C, Naimi E, Akbari A, Wiebe LI, Tandon M, Kumar P. Synthesis of [18F]FAZA using Nosyl and Iodo Precursors for Nucleophilic Radiofluorination. Current Radiopharmaceuticals. PMID 30338747 DOI: 10.2174/1874471011666181019105947 |
0.748 |
|
| 2017 |
Kumar P, Roselt P, Reischl G, Cullinane C, Beiki D, Ehrlichmann W, Binns D, Naimi E, Yang J, Hicks R, Machulla HJ, Wiebe LI. β-[18F]Fluoro Azomycin Arabinoside (β-[18F]FAZA): Synthesis, radiofluorination and preliminary PET imaging of murine A431 tumors. Current Radiopharmaceuticals. PMID 28294075 DOI: 10.2174/1874471010666170313120540 |
0.742 |
|
| 2015 |
Kumar P, Bacchu V, Wiebe LI. The chemistry and radiochemistry of hypoxia-specific, radiohalogenated nitroaromatic imaging probes. Seminars in Nuclear Medicine. 45: 122-35. PMID 25704385 DOI: 10.1053/J.Semnuclmed.2014.10.005 |
0.319 |
|
| 2015 |
Mazzuca D, Angelov C, Wiebe LI. Synthesis of dialkylaminoaryl phosphonate bioisosteres of tyrosine and tyramine: a novel application of allene phosphonate chemistry for the synthesis of false substrates of tyrosinase - Journal of Applied Pharmaceutical Science. 5: 1-9. DOI: 10.7324/Japs.2015.501101 |
0.354 |
|
| 2013 |
Xia Z, Knaus EE, Wiebe LI. Pharmacokinetics of 3'-O-retinoyl-5-fluoro-2'-deoxyuridine (RFUdR), a dual acting mutually masking prodrug, and its metabolites in tumor bearing mice. Current Drug Delivery. 10: 557-63. PMID 23755721 DOI: 10.2174/15672018113109990038 |
0.528 |
|
| 2013 |
Mercer JR, McEwan AJ, Wiebe LI. [131I]IAZA as a molecular radiotherapeutic (MRT) drug: wash-out with cold IAZA accelerates clearance in a murine tumor model. Current Radiopharmaceuticals. 6: 87-91. PMID 23551109 DOI: 10.2174/1874471011306020004 |
0.315 |
|
| 2012 |
Wuest M, Kumar P, Wang M, Yang J, Jans HS, Wiebe LI. In vitro and in vivo evaluation of [(18)F]F-GAZ, a novel oxygen-mimetic azomycin-glucose conjugate, for imaging hypoxic tumor. Cancer Biotherapy & Radiopharmaceuticals. 27: 473-80. PMID 22746267 DOI: 10.1089/Cbr.2011.1148 |
0.302 |
|
| 2012 |
Kumar P, Shustov G, Liang H, Khlebnikov V, Zheng W, Yang XH, Cheeseman C, Wiebe LI. Design, synthesis, and preliminary biological evaluation of 6-O-glucose-azomycin adducts for diagnosis and therapy of hypoxic tumors. Journal of Medicinal Chemistry. 55: 6033-46. PMID 22708968 DOI: 10.1021/Jm2017336 |
0.317 |
|
| 2012 |
Wiebe LI, Sun W, Zhou A, Yang J, Sjuvarsson EV, Eriksson S, Paproski RJ, Cass CE, Kumar P, Knaus EE. Biochemistry and biology of 2'-Fluoro-2'-deoxythymidine (FT), a putative highly selective substrate for thymidine kinase type 2 (TK2). Current Radiopharmaceuticals. 5: 38-46. PMID 21864241 DOI: 10.2174/1874471011205010038 |
0.557 |
|
| 2012 |
Chapman DW, Wuest M, Wiebe LI, Moore RB. 308 DETECTION OF FUNCTIONAL CHANGES IN RENAL CELL CARCINOMA WITH POSITRON EMISSION TOMOGRAPHY Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.367 |
0.311 |
|
| 2011 |
Bouvet VR, Wuest M, Wiebe LI, Wuest F. Synthesis of hypoxia imaging agent 1-(5-deoxy-5-fluoro-α-D-arabinofuranosyl)-2-nitroimidazole using microfluidic technology. Nuclear Medicine and Biology. 38: 235-45. PMID 21315279 DOI: 10.1016/J.Nucmedbio.2010.09.002 |
0.308 |
|
| 2010 |
Kumar P, Naimi E, McEwan AJ, Wiebe LI. Synthesis, radiofluorination, and hypoxia-selective studies of FRAZ: A configurational and positional analogue of the clinical hypoxia marker, [18F]-FAZA. Bioorganic & Medicinal Chemistry. 18: 2255-64. PMID 20181485 DOI: 10.1016/j.bmc.2010.01.064 |
0.749 |
|
| 2009 |
Stahlschmidt A, Khalili P, Sun W, MacHulla HJ, Knaus EE, Wiebe LI. Biodistribution and imaging of 1-(2-deoxy -β-D-ribofuranosyl)-2,4- difluoro-5-[123/125I]iodobenzene (dRF[123/125I]IB), a nonpolar thymidine-mimetic nucleoside, in rats and tumor-bearing mice Nucleosides, Nucleotides and Nucleic Acids. 28: 379-393. PMID 20183590 DOI: 10.1080/15257770903051072 |
0.492 |
|
| 2009 |
Seki KI, Nishijima KI, Sanoki K, Kuge Y, Takahashi M, Akizawa H, Tamaki N, Wiebe LI, Ohkura K. New [11C]phosgene based synthesis of [11C]pyrimidines for positron emission tomography Heterocycles. 77: 1307-1321. DOI: 10.3987/Com-08-S(F)116 |
0.34 |
|
| 2009 |
Sun W, Wilson J, Kumar P, Knaus E, Wiebe L. Radiosynthesis of 2-deoxy-2-[18F]fluorothymidine ([18F]FT), a Putative PET Agent for Imaging HSV-TK Expression Current Radiopharmaceuticalse. 2: 75-82. DOI: 10.2174/1874471010902010075 |
0.554 |
|
| 2008 |
Stahlschmidt A, Machulla HJ, Reischl G, Knaus EE, Wiebe LI. Radioiodination of 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-iodobenzene (dRFIB), a putative thymidine mimic nucleoside for cell proliferation studies. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 66: 1221-8. PMID 18662615 DOI: 10.1016/j.apradiso.2008.01.014 |
0.492 |
|
| 2008 |
Kumar P, Emami S, McEwan AJ, Wiebe LI. Stereospecific deuteration of alpha-furanosyl azomycin nucleosides: a model reaction for tritium radiolabeling. Bioorganic & Medicinal Chemistry Letters. 18: 3256-60. PMID 18479915 DOI: 10.1016/J.Bmcl.2008.04.055 |
0.313 |
|
| 2008 |
Li HF, Winkeler A, Moharram S, Knaus EE, Dittmar K, Stöckle M, Heiss WD, Wiebe LI, Jacobs AH, Jacob AJ. In vivo evaluation of the uptake of [(123)I]FIAU, [(123)I]IVFRU and [(123)I]IVFAU by normal mouse brain: potential for noninvasive assessment of HSV-1 thymidine kinase gene expression in gliomas. Nucleosides, Nucleotides & Nucleic Acids. 27: 57-66. PMID 18188770 DOI: 10.1080/15257770701571933 |
0.53 |
|
| 2007 |
Cristofoli WA, Wiebe LI, De Clercq E, Andrei G, Snoeck R, Balzarini J, Knaus EE. 5-alkynyl analogs of arabinouridine and 2'-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells. Journal of Medicinal Chemistry. 50: 2851-7. PMID 17518459 DOI: 10.1021/Jm0701472 |
0.542 |
|
| 2006 |
Wiebe LI, Knaus EE, Iwashina T, Misra H, Lee YW. 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-[36Cl]chlorouracil; Radiosynthesis and Preliminary Biodistribution Studies in an Experimental Murine Tumor Model Collection of Czechoslovak Chemical Communications. 71: 1051-1062. DOI: 10.1135/Cccc20061051 |
0.58 |
|
| 2006 |
Tandon M, Kumar P, Xia H, Wang L, Wiebe LI. Synthesis of Bromophenyl β-D-Glucuronides: Hydrophilic Precursors of Lipophilic Standards in the Analysis of Environmental Polychlorinated Biphenyls Collection of Czechoslovak Chemical Communications. 71: 1042-1050. DOI: 10.1135/Cccc20061042 |
0.358 |
|
| 2005 |
Moharram S, Zhou A, Kumar P, Knaus EE, Wiebe LI. Radiosynthesis, in vitro cellular uptake and in vivo biodistribution of 3'-O-(3-benzenesulfonylfuroxan-4-yl)-5-[125I]iodo-2'-deoxyuridine, a nucleoside-based nitric oxide donor. Nuclear Medicine and Biology. 32: 641-5. PMID 16026711 DOI: 10.1016/J.Nucmedbio.2005.04.011 |
0.516 |
|
| 2005 |
Morin KW, Duan W, Knaus EE, McEwan AJ, Wiebe LI. A human osteosarcoma cell line expressing herpes simplex type-1 thymidine kinase: studies with radiolabeled (E)-5-(2-iodovinyl)-2'-fluoro-2'-deoxyuridine. Nuclear Medicine and Biology. 32: 459-64. PMID 15982576 DOI: 10.1016/J.Nucmedbio.2005.03.006 |
0.513 |
|
| 2005 |
Naimi E, Kumar P, McEwan AJ, Wiebe LI. A one-pot synthesis of 1-alpha- and 1-beta-D-arabinofuranosyl-2-nitroimidazoles: synthons to the markers of tumor hypoxia. Nucleosides, Nucleotides & Nucleic Acids. 24: 173-8. PMID 15892256 DOI: 10.1081/Ncn-55700 |
0.745 |
|
| 2005 |
Reischl G, Ehrlichmann W, Bieg C, Solbach C, Kumar P, Wiebe LI, Machulla HJ. Preparation of the hypoxia imaging PET tracer [18F]FAZA: reaction parameters and automation. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 62: 897-901. PMID 15799867 DOI: 10.1016/J.Apradiso.2004.12.004 |
0.336 |
|
| 2005 |
Kumar P, Zheng W, McQuarrie SA, Jhamandas JH, Wiebe LI. 18F-FESB: synthesis and automated radiofluorination of a novel18F-labeled pet tracer forβ-amyloid plaques Journal of Labelled Compounds and Radiopharmaceuticals. 48: 983-996. DOI: 10.1002/Jlcr.1011 |
0.336 |
|
| 2004 |
Al-Madhoun AS, Eriksson S, Wang ZX, Naimi E, Knaus EE, Wiebe LI. Phosphorylation of isocarbostyril- and difluorophenyl-nucleoside thymidine mimics by the human deoxynucleoside kinases. Nucleosides, Nucleotides & Nucleic Acids. 23: 1865-74. PMID 15628745 DOI: 10.1081/Ncn-200040634 |
0.77 |
|
| 2004 |
Ohkura K, Sun WY, Seki K, Knaus EE, Wiebe LI. (2S)-2-[1-(2,4-Difluoro-5-iodophenyl)-2-deoxy-beta-D-ribofuranos-5-yloxy]-8-methyl-4H-1,3,2-benzodioxaphosphole 2-oxide. Acta Crystallographica. Section C, Crystal Structure Communications. 60: o789-91. PMID 15528820 DOI: 10.1107/S0108270104021602 |
0.569 |
|
| 2004 |
Morin KW, Duan W, Xu L, Zhou A, Moharram S, Knaus EE, McEwan AJ, Wiebe LI. Cytotoxicity and cellular uptake of pyrimidine nucleosides for imaging herpes simplex type-1 thymidine kinase (HSV-1 TK) expression in mammalian cells. Nuclear Medicine and Biology. 31: 623-30. PMID 15219281 DOI: 10.1016/J.Nucmedbio.2004.02.004 |
0.552 |
|
| 2004 |
Smith KM, Ng AM, Yao SY, Labedz KA, Knaus EE, Wiebe LI, Cass CE, Baldwin SA, Chen XZ, Karpinski E, Young JD. Electrophysiological characterization of a recombinant human Na+-coupled nucleoside transporter (hCNT1) produced in Xenopus oocytes. The Journal of Physiology. 558: 807-23. PMID 15194733 DOI: 10.1113/Jphysiol.2004.068189 |
0.502 |
|
| 2004 |
Verwijnen SM, Sillevis Smith PA, Hoeben RC, Rabelink MJ, Wiebe L, Curiel DT, Hemminki A, Krenning EP, de Jong M. Molecular imaging and treatment of malignant gliomas following adenoviral transfer of the herpes simplex virus-thymidine kinase gene and the somatostatin receptor subtype 2 gene. Cancer Biotherapy & Radiopharmaceuticals. 19: 111-20. PMID 15068619 DOI: 10.1089/108497804773391757 |
0.306 |
|
| 2004 |
Kumar P, Ohkura K, Balzarini J, De Clercq E, Seki K, Wiebe LI. Synthesis and antiviral activity of novel fluorinated 2',3'-dideoxynucleosides. Nucleosides, Nucleotides & Nucleic Acids. 23: 7-29. PMID 15043133 DOI: 10.1081/Ncn-120027814 |
0.332 |
|
| 2004 |
Moharram S, Zhou A, Wiebe LI, Knaus EE. Design and synthesis of 3'- and 5'-O-(3-benzenesulfonylfuroxan-4-yl)-2'-deoxyuridines: biological evaluation as hybrid nitric oxide donor-nucleoside anticancer agents. Journal of Medicinal Chemistry. 47: 1840-6. PMID 15027876 DOI: 10.1021/Jm030544M |
0.574 |
|
| 2003 |
Sun WY, Zhou A, Wiebe LI, Knaus EE. Cyclosaligenyl pronucleotides of 5-iodo and 5-trifluoromethyl-1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluorobenzene mimics of thymidine: synthesis and evaluation of this pronucleotide monophosphate delivery system for compounds with potential anticancer activity. Nucleosides, Nucleotides & Nucleic Acids. 22: 2121-32. PMID 14714761 DOI: 10.1081/Ncn-120026634 |
0.582 |
|
| 2003 |
Khalili P, Naimi E, Sun WY, Knaus EE, Wiebe LI. Dose-dependent pharmacokinetics of 1(2-deoxy-β-D-ribofuranosyl)-2,4-difluoro-5-iodobenzene: A potential mimic of 5-iodo-2′-deoxyuridine Biopharmaceutics and Drug Disposition. 24: 385-395. PMID 14689467 DOI: 10.1002/Bdd.375 |
0.759 |
|
| 2003 |
Khalili P, Naimi E, Sun WY, Knaus EE, Wiebe LI. Biochemical and pharmacokinetic evaluation of a novel pyrimidine nucleoside nitric oxide donor as a potential anticancer/antiviral agent European Journal of Pharmaceutical Sciences. 19: 305-313. PMID 12885396 DOI: 10.1016/S0928-0987(03)00132-5 |
0.781 |
|
| 2003 |
Sorger D, Patt M, Kumar P, Wiebe LI, Barthel H, Seese A, Dannenberg C, Tannapfel A, Kluge R, Sabri O. [18F]Fluoroazomycinarabinofuranoside (18FAZA) and [18F]Fluoromisonidazole (18FMISO): a comparative study of their selective uptake in hypoxic cells and PET imaging in experimental rat tumors. Nuclear Medicine and Biology. 30: 317-26. PMID 12745023 DOI: 10.1016/S0969-8051(02)00442-0 |
0.302 |
|
| 2003 |
Kumar P, Ohkura K, Beiki D, Wiebe LI, Seki K. Synthesis of 1-beta-D-(5-deoxy-5-iodoarabinofuranosyl)-2-nitroimidazole (beta-IAZA): a novel marker of tissue hypoxia. Chemical & Pharmaceutical Bulletin. 51: 399-403. PMID 12672991 DOI: 10.1248/Cpb.51.399 |
0.302 |
|
| 2003 |
Naimi E, Zhou A, Khalili P, Wiebe LI, Balzarini J, De Clercq E, Knaus EE. Synthesis of 3′- and 5′-nitrooxy pyrimidine nucleoside nitrate esters: "Nitric oxide donor" agents for evaluation as anticancer and antiviral agents Journal of Medicinal Chemistry. 46: 995-1004. PMID 12620076 DOI: 10.1021/Jm020299R |
0.802 |
|
| 2002 |
Kumar P, Wiebe LI, Mannan RH, Zhang Z, Xia H, McEwan AJ. [99mTc]Technetium labelled PnAo-azomycin glucuronides: a novel class of imaging markers of tissue hypoxia. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 57: 719-28. PMID 12433047 DOI: 10.1016/S0969-8043(02)00188-4 |
0.349 |
|
| 2002 |
Nanda D, de Jong M, Vogels R, Havenga M, Driesse M, Bakker W, Bijster M, Avezaat C, Cox P, Morin K, Naimi E, Knaus E, Wiebe L, Smitt PS. Imaging expression of adenoviral HSV1-tk suicide gene transfer using the nucleoside analogue FIRU. European Journal of Nuclear Medicine and Molecular Imaging. 29: 939-47. PMID 12212546 DOI: 10.1007/S00259-002-0839-9 |
0.783 |
|
| 2002 |
Khalili P, Naimi E, Knaus EE, Wiebe LI. Pharmacokinetics and metabolism of the novel synthetic C-nucleoside, 1-(2-deoxy-β-D-ribofuranosyl)-2,4-difluoro-5-iodobenzene: A potential mimic of 5-iodo-2′-deoxyuridine Biopharmaceutics and Drug Disposition. 23: 105-113. PMID 12173545 DOI: 10.1002/Bdd.301 |
0.795 |
|
| 2002 |
Kumar R, Wang L, Wiebe LI, Knaus EE. Synthesis and biological investigations of 5-substituted pyrimidine nucleosides coupled to a dihydropyridine/pyridinium salt redox chemical delivery system. Archiv Der Pharmazie. 334: 351-6. PMID 11822172 DOI: 10.1002/1521-4184(200112)334:11<351::Aid-Ardp351>3.0.Co;2-D |
0.56 |
|
| 2002 |
Wiebe LI, Knaus EE. Enzyme-targeted, nucleoside-based radiopharmaceuticals for scintigraphic monitoring of gene transfer and expression. Current Pharmaceutical Design. 7: 1893-906. PMID 11772356 DOI: 10.2174/1381612013396817 |
0.49 |
|
| 2002 |
Kumar P, Wiebe LI, Beiki D, Ohkura K, Seki K. Synthesis of β-azomycin nucleosides: 1-(β-d-2-iodo-2-deoxyarabinofuranosyl)-2-nitroimidazole (β-2-IAZA), a novel marker of tissue hypoxia Tetrahedron Letters. 43: 4427-4429. DOI: 10.1016/S0040-4039(02)00845-6 |
0.325 |
|
| 2001 |
Naimi E, Duan W, Wiebe LI, Knaus EE. Synthesis of unnatural 7-substituted-1-(2-deoxy-beta-D-ribofuranosyl)isocarbostyrils: "thymine replacement" analogs of deoxythymidine for evaluation as antiviral and anticancer agents. Nucleosides, Nucleotides & Nucleic Acids. 20: 1533-53. PMID 11554544 DOI: 10.1081/Ncn-100105246 |
0.792 |
|
| 2001 |
Mark BL, Parrish JC, Wang ZX, Wiebe LI, Knaus EE, James MN. (E)-1-(2'-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-(2-iodovinyl)benzene. Acta Crystallographica. Section C, Crystal Structure Communications. 57: 758-60. PMID 11408697 DOI: 10.1107/S0108270101005029 |
0.52 |
|
| 2001 |
Wang ZX, Duan W, Wiebe LI, Balzarini J, De Clercq E, Knaus EE. Synthesis of 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-substituted-benzenes: "thymine replacement" analogs of thymidine for evaluation as anticancer and antiviral agents. Nucleosides, Nucleotides & Nucleic Acids. 20: 41-58. PMID 11303562 DOI: 10.1081/Ncn-100001436 |
0.568 |
|
| 2001 |
Wang ZX, Duan W, Wiebe LI, Balzarini J, De Clercq E, Knaus EE. Synthesis of 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-substituted-benzene thymidine mimics, some related alpha-anomers, and their evaluation as antiviral and anticancer agents. Nucleosides, Nucleotides & Nucleic Acids. 20: 11-40. PMID 11303557 DOI: 10.1081/Ncn-100001435 |
0.562 |
|
| 2001 |
Wang ZX, Wiebe LI, Balzarini J, De Clercq E, Knaus EE. Chiral synthesis of 4-[1-(2-deoxy-beta-L-ribofuranosyl)] derivatives of 2-substituted 5-fluoroaniline: "cytosine replacement" analogues of deoxy-beta-L-cytidine. The Journal of Organic Chemistry. 65: 9214-9. PMID 11149873 DOI: 10.1021/Jo000510B |
0.513 |
|
| 2001 |
Wang ZX, Duan W, Wiebe LI, De Clercq E, Balzarini J, Knaus EE. Syntheses of 1-[(2-hydroxyethoxy)methyl]- and 1-[(1,3-dihydroxy-2-propoxy)methyl]- derivatives of 5-substituted-2,4-difluorobenzene: unnatural acyclo thymidine mimics for evaluation as anticancer and antiviral agents. Nucleosides, Nucleotides & Nucleic Acids. 19: 1397-411. PMID 11092311 DOI: 10.1080/15257770008033850 |
0.58 |
|
| 2001 |
Naimi E, Wiebe LI, Balzarini J, De Clercq E, Knaus EE. Synthesis of 1-(2-deoxy-?-D-ribofuranosyl)-2,4- difluoro-5-(2-halo-1-hydroxyethyl)benzenes and related derivatives: ?thymine replacement? analogs of deoxythymidine for evaluation as antiviral and anticancer agents Drug Development Research. 52: 492-499. DOI: 10.1002/Ddr.1151 |
0.8 |
|
| 2000 |
Parang K, Wiebe LI, Knaus EE. Novel approaches for designing 5'-O-ester prodrugs of 3'-Azido-2',3'-dideoxythymidine (AZT) Current Medicinal Chemistry. 7: 995-1039. PMID 10911016 DOI: 10.2174/0929867003374372 |
0.672 |
|
| 2000 |
Morin KW, Knaus EE, Wiebe LI, Xia H, McEwan AJ. Reporter gene imaging: effects of ganciclovir treatment on nucleoside uptake, hypoxia and perfusion in a murine gene therapy tumour model that expresses herpes simplex type-1 thymidine kinase. Nuclear Medicine Communications. 21: 129-37. PMID 10758606 DOI: 10.1097/00006231-200002000-00002 |
0.301 |
|
| 2000 |
Lee HC, Kumar P, McEwan AJ, Wiebe LI, Mercer JR. Synthesis, radiolabeling, and biodistribution of putative metabolites of iodoazomycin arabinoside. Nuclear Medicine and Biology. 27: 61-8. PMID 10755647 DOI: 10.1016/S0969-8051(99)00089-X |
0.374 |
|
| 2000 |
Wang Z, Wiebe LI, Clercq ED, Balzarini J, Knaus EE. Syntheses of 4-[1-(2-deoxy-β-D-ribofuranosyl)]-derivatives of 2-substituted-5-fluoroaniline: "cytosine replacement" analogs of deoxycytidine for evaluation as anticancer and antihuman immunodeficiency virus (anti-HIV) agents Canadian Journal of Chemistry. 78: 1081-1088. DOI: 10.1139/V00-105 |
0.604 |
|
| 1999 |
Wiebe LI, Knaus EE. Concepts for the design of anti-HIV nucleoside prodrugs for treating cephalic HIV infection. Advanced Drug Delivery Reviews. 39: 63-80. PMID 10837768 DOI: 10.1016/S0169-409X(99)00020-4 |
0.542 |
|
| 1999 |
Xia Z, Wiebe LI, Miller GG, Knaus EE. Synthesis and biological evaluation of butanoate, retinoate, and bis(2,2,2-trichloroethyl)phosphate derivatives of 5-fluoro-2'-deoxyuridine and 2',5-difluoro-2'-deoxyuridine as potential dual action anticancer prodrugs. Archiv Der Pharmazie. 332: 286-94. PMID 10489539 DOI: 10.1002/(Sici)1521-4184(19998)332:8<286::Aid-Ardp286>3.0.Co;2-9 |
0.557 |
|
| 1999 |
Wiebe LI, Knaus EE, Morin KW. Radiolabelled pyrimidine nucleosides to monitor the expression of HSV-1 thymidine kinase in gene therapy. Nucleosides & Nucleotides. 18: 1065-6. PMID 10432739 DOI: 10.1080/15257779908041646 |
0.521 |
|
| 1999 |
Lee HC, Kumar P, Wiebe LI, McDonald R, Mercer JR, Ohkura K, Seki K. Synthesis of Iodoaminoimidazole Arabinoside (IAIA): A Potential Reductive Metabolite of the Spect Imaging Agent, Iodoazomycin Arabinoside (IAZA) Nucleosides and Nucleotides. 18: 1995-2016. DOI: 10.1080/07328319908044860 |
0.327 |
|
| 1999 |
Kumar P, Stypinski D, Xia H, McEwan AJB, Machulla H, Wiebe LI. Fluoroazomycin arabinoside (FAZA): synthesis,2H and3H-labelling and preliminary biological evaluation of a novel 2-nitroimidazole marker of tissue hypoxia Journal of Labelled Compounds and Radiopharmaceuticals. 42: 3-16. DOI: 10.1002/(Sici)1099-1344(199901)42:1<3::Aid-Jlcr160>3.0.Co;2-H |
0.414 |
|
| 1998 |
Parang K, Wiebe LI, Knaus EE. Synthesis, in vitro anti-human immunodeficiency virus structure-activity relationships and biological stability of 5'-O-myristoyl analogue derivatives of 3'-azido-2',3'-dideoxythymidine (AZT) as potential prodrugs Antiviral Chemistry and Chemotherapy. 9: 311-323. PMID 9875410 DOI: 10.1177/095632029800900403 |
0.685 |
|
| 1998 |
Parang K, Wiebe LI, Knaus EE. Pharmacokinetics and tissue distribution of (±)-3'-azido-2',3'-dideoxy-5'-O-(2-bromomyristoyl)thymidine, a prodrug of 3'-azido-2',3'-dideoxythymidine (AZT) in mice Journal of Pharmacy and Pharmacology. 50: 989-996. PMID 9811159 DOI: 10.1111/J.2042-7158.1998.Tb06913.X |
0.643 |
|
| 1998 |
Parang K, Knaus EE, Wiebe LI. Synthesis, in vitro anti-HIV activity, and biological stability of 5'- O-myristoyl analogue derivatives of 3'-fluoro-2',3'dideoxythymidine (FLT) as potential bifunctional prodrugs of FLT Nucleosides and Nucleotides. 17: 987-1008. PMID 9708320 DOI: 10.1080/07328319808004216 |
0.663 |
|
| 1998 |
Balzarini J, Stet L, Matsuda A, Wiebe L, Knauss E, De Clercq E. Metabolism of EICAR (5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide), a potent inhibitor of inosinate dehydrogenase. Advances in Experimental Medicine and Biology. 431: 723-8. PMID 9598159 DOI: 10.1016/S0009-9120(97)87643-6 |
0.352 |
|
| 1997 |
Degrève B, Andrei G, Izquierdo M, Piette J, Morin K, Knaus EE, Wiebe LI, Basrah I, Walker RT, De Clercq E, Balzarini J. Varicella-zoster virus thymidine kinase gene and antiherpetic pyrimidine nucleoside analogues in a combined gene/chemotherapy treatment for cancer. Gene Therapy. 4: 1107-14. PMID 9415318 DOI: 10.1038/Sj.Gt.3300502 |
0.567 |
|
| 1997 |
Kumar R, Wiebe LI, Knaus EE. Synthesis and antiviral activity of 5-ethyl-5-halo-6-alkoxy-(or azido)-5,6-dihydro-2'-deoxyuridine diastereomers as potential prodrugs to 5-ethyl-2'-deoxyuridine. Archiv Der Pharmazie. 330: 259-63. PMID 9361522 DOI: 10.1002/Ardp.19973300806 |
0.548 |
|
| 1997 |
Morin KW, Atrazheva ED, Knaus EE, Wiebe LI. Synthesis and cellular uptake of 2'-substituted analogues of (E)-5-(2-[125I]iodovinyl)-2'-deoxyuridine in tumor cells transduced with the herpes simplex type-1 thymidine kinase gene. Evaluation as probes for monitoring gene therapy. Journal of Medicinal Chemistry. 40: 2184-90. PMID 9216837 DOI: 10.1021/Jm9606406 |
0.565 |
|
| 1997 |
Parang K, Wiebe LI, Knaus EE, Huang JS, Tyrrell DL, Csizmadia F. In vitro antiviral activities of myristic acid analogs against human immunodeficiency and hepatitis B viruses Antiviral Research. 34: 75-90. PMID 9191015 DOI: 10.1016/S0166-3542(96)01022-4 |
0.659 |
|
| 1997 |
Parang K, Wiebe LI, Knaus EE. Syntheses and biological evaluation of 5'-O-myristoyl derivatives of thymidine against human immunodeficiency virus Antiviral Chemistry and Chemotherapy. 8: 417-427. DOI: 10.1177/095632029700800504 |
0.656 |
|
| 1997 |
Kumar R, Wiebe LI, Knaus EE. Synthesis of 5-(1-azido-2-haloethyl)arabinouridines Journal of Heterocyclic Chemistry. 34: 1369-1370. DOI: 10.1002/Jhet.5570340445 |
0.535 |
|
| 1996 |
Parang K, Knaus EE, Wiebe LI, Sardari S, Daneshtalab M, Csizmadia F. Synthesis and antifungal activities of myristic acid analogs Archiv Der Pharmazie. 329: 475-482. PMID 8997896 DOI: 10.1002/Ardp.19963291102 |
0.642 |
|
| 1996 |
Wang L, Morin KW, Kumar R, Cheraghali M, Todd KG, Baker GB, Knaus EE, Wiebe LI. In vivo biodistribution, pharmacokinetic parameters, and brain uptake of 5-halo-y-methoxy(or ethoxy)-5,6-dihydro-3'-azido-3'-deoxythymidine diastereomers as potential prodrugs of 3'-azido-3'-deoxythymidine. Journal of Medicinal Chemistry. 39: 826-33. PMID 8632406 DOI: 10.1021/Jm9408326 |
0.51 |
|
| 1996 |
Kumar R, Wiebe LI, Knaus EE. Synthesis of 5-(1-azidovinyl) and 5-[2-(1-azirinyl)] analogs of 2′-deoxyuridine Canadian Journal of Chemistry. 74: 1609-1615. DOI: 10.1139/V96-178 |
0.574 |
|
| 1996 |
Kumar R, Wang L, Wiebe LI, Knaus EE. Synthesis, In Vitro Biological Stability, and Anti-HIV Activity of 5-Halo (or Methoxy)-6-Alkoxy (Azido or Hydroxy)-5,6-Dihydro-2′,3′-Didehydro-3′-Deoxythymidine Diastereomers as Potential Prodrugs of 2′,3′-Didehydro-3′-deoxythymidine (D4T) Nucleosides and Nucleotides. 15: 265-286. DOI: 10.1080/07328319608002384 |
0.582 |
|
| 1996 |
Minakawa N, Matsuda A, Xia Z, Wiebe LI, Knaus EE. Syntheses of [2-2H]-5-ethynyl-1-(β-D-ribofuranosyl)imidazole-4-carboxamide and 5-ethynyl-1-([5-3H]-β-D-ribofuranosyl)imidazole-4-carboxamide (EICAR) Journal of Labelled Compounds and Radiopharmaceuticals. 38: 809-824. DOI: 10.1002/(Sici)1099-1344(199609)38:9<809::Aid-Jlcr899>3.0.Co;2-0 |
0.551 |
|
| 1995 |
Verheggen I, Aerschot AV, Meervelt LV, Rozenski J, Wiebe L, Snoeck R, Andrei G, Balzarini J, Claes P. Synthesis, Biological Evaluation, and Structure Analysis of a Series of New 1,5-Anhydrohexitol Nucleosides Journal of Medicinal Chemistry. 38: 826-835. PMID 7877148 DOI: 10.1021/Jm00005A010 |
0.356 |
|
| 1995 |
Cheraghali AM, Knaus EE, Wiebe LI. Bioavailability and pharmacokinetic parameters for 5-ethyl-2'-deoxyuridine. Antiviral Research. 25: 259-67. PMID 7710272 DOI: 10.1016/0166-3542(94)90008-6 |
0.498 |
|
| 1995 |
Balzarini J, Andrei G, Kumar R, Knaus EE, Wiebe LI, De Clercq E. The cytostatic activity of 5-(1-azidovinyl)-2'-deoxyuridine (AzVDU) against herpes simplex virus thymidine kinase gene-transfected FM3A cells is due to inhibition of thymidylate synthase and enhanced by UV light (lambda = 254 nm) exposure. Febs Letters. 373: 41-4. PMID 7589430 DOI: 10.1016/0014-5793(95)00994-K |
0.541 |
|
| 1995 |
Cheraghali AM, Kumar R, Morin KW, De Clercq E, Knaus EE, Wiebe LI. A Comparative Study of 5-ethyl-2′-Deoxyuridine and Selected Lipophilic 5,6-Dihydro Double/Triple Prodrugs Antiviral Chemistry and Chemotherapy. 6: 356-364. DOI: 10.1177/095632029500600602 |
0.576 |
|
| 1995 |
Luyten I, Jie L, Van Aerschot A, Pannecouque C, Wigerinck P, Rozenski J, Hendrix C, Wang C, Wiebe L, Balzarini J, De Clercq E, Herdewijn P. 2′-Deoxyuridines with a 5-Heteroaromatic Substituent: Synthesis and Biological Evaluation Antiviral Chemistry and Chemotherapy. 6: 262-270. DOI: 10.1177/095632029500600409 |
0.407 |
|
| 1995 |
Cheraghali AM, Morin KW, Kumar R, Knaus EE, Wiebe LI. Accumulation of 5-Ethyl-2′-deoxyuridine and its 5,6-Dihydro Prodrugs in Murine Lung and its Potential Clinical Application Journal of Pharmacy and Pharmacology. 47: 595-600. DOI: 10.1111/J.2042-7158.1995.Tb06721.X |
0.513 |
|
| 1995 |
Wiebe L, Knaus E, Cheraghali AM, Kumar R, Morin K, Wang L. 5-Halo-6-alkoxy-5,6-dihydro-pyrimidine Nucleosides: Antiviral Nucleosides or Nucleoside Prodrugs? Nucleosides, Nucleotides and Nucleic Acids. 14: 501-505. DOI: 10.1080/15257779508012413 |
0.535 |
|
| 1994 |
Morin KW, Wiebe LI, Knaus EE. Synthesis of brain-targeted 1-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-(E)-5-(2-iodovinyl)uracil coupled to a dihydropyridine <---> pyridinium salt redox chemical-delivery system. Carbohydrate Research. 249: 109-16. PMID 8252549 DOI: 10.1016/0008-6215(93)84064-D |
0.57 |
|
| 1994 |
Cheraghali AM, Kumar R, Wang L, Knaus EE, Wiebe LI. Synthesis, biotransformation, pharmacokinetics, and antiviral properties of 5-ethyl-5-halo-6-methoxy-5,6-dihydro-2'-deoxyuridine diastereomers. Biochemical Pharmacology. 47: 1615-25. PMID 8185676 DOI: 10.1016/0006-2952(94)90540-1 |
0.548 |
|
| 1994 |
Tandon M, Kumar P, Wiebe LI. alpha-Trifluoromethyl-beta-alanyl glycine (F3MBAG): a novel mammalian metabolite of trifluridine (F3TdR). Biochemical Pharmacology. 48: 1033-41. PMID 8093091 DOI: 10.1016/0006-2952(94)90375-1 |
0.317 |
|
| 1994 |
Iwashina T, Jimbow K, Wiebe LI. The synthesis of N-acetyl-4-S-cysteaminyl [U-14C]phenol as a basis for the development of an antimelanoma and melanoma-radioimaging agent. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 45: 703-5. PMID 8038763 DOI: 10.1016/0969-8043(94)90250-X |
0.31 |
|
| 1994 |
Kumar R, Wang L, Wiebe LI, Knaus EE. Synthesis, in vitro biological stability, and anti-HIV activity of 5-halo-6-alkoxy(or azido)-5,6-dihydro-3'-azido-3'-deoxythymidine diastereomers as potential prodrugs to 3'-azido-3'-deoxythymidine (AZT). Journal of Medicinal Chemistry. 37: 4297-306. PMID 7996541 DOI: 10.1021/Jm00051A006 |
0.577 |
|
| 1994 |
Kumar R, Wang L, Wiebe LI, Knaus EE. Synthesis and antiviral (HIV-1, HBV) activities of 5-halo-6-methoxy(or azido)-5,6-dihydro-3'-fluoro-3'-deoxythymidine diastereomers. Potential prodrugs to 3'-fluoro-3'-deoxythymidine. Journal of Medicinal Chemistry. 37: 3554-60. PMID 7932583 DOI: 10.1021/Jm00047A013 |
0.559 |
|
| 1994 |
Kumar R, Wiebe LI, Knaus EE. A mild and efficient methodology for the synthesis of 5-halogeno uracil nucleosides that occurs via a 5-halogeno-6-azido-5,6-dihydro intermediate Canadian Journal of Chemistry. 72: 2005-2010. DOI: 10.1139/V94-256 |
0.559 |
|
| 1993 |
Kumar R, Wiebe LI, Knaus EE. Synthesis and antiviral activity of novel 5-(1-azido-2-haloethyl) and 5-(1-azido-, amino-, or methoxyethyl) analogs of 2'-deoxyuridine. Journal of Medicinal Chemistry. 36: 2470-4. PMID 8394933 DOI: 10.1021/Jm00069A004 |
0.567 |
|
| 1993 |
Tandon M, Kumar P, Wiebe G, Wiebe LI. Detection of new metabolites of trifluridine (F3TdR) using 19F NMR spectroscopy. Biochemical Pharmacology. 44: 2223-8. PMID 1472088 DOI: 10.1016/0006-2952(92)90350-R |
0.315 |
|
| 1993 |
Blanchard H, James MNG, Kumar R, Wiebe LI, Knaus EE. Structure of (+)-(5R,6R)-5-chloro-6-methoxy-5,6-dihydro-1-(2',3'-didehydro-2',3'-dideoxy-β-d-glycero-2-enopentofuranosyl)thymine Acta Crystallographica Section C-Crystal Structure Communications. 49: 246-250. DOI: 10.1107/S0108270192003470 |
0.526 |
|
| 1993 |
Kumar R, Wiebe LI, Knaus EE. Synthesis and Antiviral Activity of 1-β-D-Arabinofuranosyluracils and Uridines Containing 5-[2-Bromo-2-chloro (or Bromo)-1-Hydroxy (or Methoxy) Ethyl] Substituents Nucleosides and Nucleotides. 12: 537-545. DOI: 10.1080/07328319308021221 |
0.571 |
|
| 1993 |
Kumar R, Knaus EE, Wiebe LI. Synthesis of (E)-5-(2-cIOdovinyl)-3′-0-(1-Methyl-1,4-Dihydropyridyl-3 -Carbonyl)-2′-Fluoro-2′-Deoxyuridine (Ivfru-Cds) for Brain Targetted Delivery of Ivfru, an Antiviral Nucleoside Nucleosides and Nucleotides. 12: 895-904. DOI: 10.1080/07328319308018560 |
0.567 |
|
| 1993 |
Tandon M, Kumar P, Wiebe LI. α-Trifluoromethyl-β-Ureido-Propionic Acid (F3MUPA): A New Metabolite of Trifluridine (F3TdR) Nucleosides and Nucleotides. 12: 803-814. DOI: 10.1080/07328319308018551 |
0.327 |
|
| 1992 |
Mannan RH, Mercer JR, Wiebe LI, Somayaji VV, Chapman JD. Radioiodinated 1-(2-Fluoro-4-Iodo-2,4-Dideoxy-β-L-Xylopyranosyl)-2-Nitroimidazole: A Novel Probe for the Noninvasive Assessment of Tumor Hypoxia Radiation Research. 132: 368. DOI: 10.2307/3578246 |
0.331 |
|
| 1992 |
Kumar P, Wiebe LI. Synthesis of Novel Fluorinated 2′,3′-Dideoxynucleosides Nucleosides and Nucleotides. 11: 401-416. DOI: 10.1080/07328319208021714 |
0.349 |
|
| 1992 |
Kumar R, Knaus EE, Wiebe LI. Synthesis and Anti-Hiv Activity of 3′-0-Formyl Derivatives of Thymidine and 2′-Deoxyuridine Nucleosides and Nucleotides. 11: 1219-1228. DOI: 10.1080/07328319208018337 |
0.57 |
|
| 1991 |
Kumar R, Knaus E, Wiebe L, Allen T, Tempest M. Synthesis and cytotoxic activity of 5-(1-hydroxy-2-haloethyl)-, 5-oxiranyl- and (E)-5-(2-iodovinyl)-2,4-dichloro (or dimethoxy) pyrimidines European Journal of Medicinal Chemistry. 26: 557-562. DOI: 10.1016/0223-5234(91)90153-E |
0.555 |
|
| 1991 |
Knaus E, Tandon M, Temptest M, Wiebe L. Design, synthesis and configuration of 5-[2,2-Dichloro )or 2-chloro) cyclopropyl]-2′-deoxyuridines Antiviral Research. 15: 44. DOI: 10.1016/0166-3542(91)90088-9 |
0.509 |
|
| 1991 |
Kumar R, Knaus EE, Wiebe LI. Synthesis and properties of 5-(1,2-dihaloethyl)-2′-deoxyuridines and related analogues Journal of Heterocyclic Chemistry. 28: 1917-1925. DOI: 10.1002/Jhet.5570280819 |
0.585 |
|
| 1991 |
Kumar R, Wiebe LI, Knaus EE, Nakashima TT. Aziridination of the uracil 5,6-olefinic bond of 3-N-3′,5′-Di-O-tribenzoyl-5-vinyl-2′-deoxyuridine Journal of Heterocyclic Chemistry. 28: 1467-1468. DOI: 10.1002/Jhet.5570280549 |
0.545 |
|
| 1991 |
Morin KW, Kumar R, Knaus EE, Wiebe LI. Design and synthesis of the 3′-aminocarbonylamino, aminothiocarbonylamino andN-(Hydroxy)guanidinyl derivatives of thymidine as potential anti-HIV agents Journal of Heterocyclic Chemistry. 28: 807-809. DOI: 10.1002/Jhet.5570280346 |
0.574 |
|
| 1991 |
Kumar R, Ji G, Wiebe LI, Knaus EE. Synthesis of brain-targeted 5-iodo-, 5-vinyl- and (E)-5-(2-iodovinyl)-2′-deoxyuridines coupled to a dihydropyridine ⇌ pyridinium salt redox chemical delivery system Journal of Heterocyclic Chemistry. 28: 711-715. DOI: 10.1002/Jhet.5570280327 |
0.572 |
|
| 1991 |
Kumar R, Wiebe LI, Knaus EE, Tempest ML. Synthesis and biological evaluation of 5-(1-alkoxy-2-haloethyl)-2′-deoxyuridines and related uracil analogues Journal of Heterocyclic Chemistry. 28: 237-240. DOI: 10.1002/Jhet.5570280206 |
0.563 |
|
| 1990 |
Wiebe LI, Knaus EE, Gati WP, Iwashina T, McQueen L. Drug-induced perturbations in the in vivo distribution of oncological radiotracers--II. 5-[125I]iodo-2'-deoxyuridine influenced by nitrobenzylthioinosine-5'-phosphate (NBMPR-P) and acyclothymidine (ACT). International Journal of Radiation Applications and Instrumentation. Part a, Applied Radiation and Isotopes. 41: 159-62. PMID 2158945 DOI: 10.1016/0883-2889(90)90101-L |
0.531 |
|
| 1990 |
Mosimann SC, Santarsiero BD, James MNG, Tandon M, Wiebe LI, Knaus EE. Structure of 5-[(1S,2S)-2-chlorocyclopropyl]-1-(2-deoxy-β-D-ribofuranosyl)uracil Acta Crystallographica Section C Crystal Structure Communications. 46: 2115-2117. DOI: 10.1107/S0108270190000634 |
0.532 |
|
| 1990 |
Kumar P, Wiebe LI. The Synthesis of Novel 5-Trifluoroethoxy Pyrimidine Nucleosides Nucleosides and Nucleotides. 9: 861-873. DOI: 10.1080/15257779008043151 |
0.317 |
|
| 1990 |
Kumar P, Wiebe LI. The Synthesis of Novel 5-Trifluoroethyl Ethers of Thymidine Nucleosides and Nucleotides. 9: 847-859. DOI: 10.1080/15257779008043150 |
0.33 |
|
| 1990 |
Iwashina T, Knaus EE, Wiebe LI, Xu L, Tyrrell D, Tovell DR. Synthesis and biological properties of (E)-5-(2-[82Br]bromovinyl)-1-(2-deoxy-2-fluoro-β-d-ribofuranosyl)uracil ([82Br]BVFRU) International Journal of Radiation Applications and Instrumentation. Part a. Applied Radiation and Isotopes. 41: 675-678. DOI: 10.1016/0883-2889(90)90083-S |
0.577 |
|
| 1990 |
Iwashina T, Kumar R, Knaus EE, Wiebe LI. An efficient, high specific activity radioiodination of 5-(1-hydroxy/methoxy-2-iodoethyl)-2′-deoxyuridine by isotope exchange labelling in pivalic acid melt Journal of Labelled Compounds and Radiopharmaceuticals. 28: 247-255. DOI: 10.1002/Jlcr.2580280302 |
0.536 |
|
| 1989 |
Tse JW, Wiebe LI, Noujaim AA. Comparative studies of radiotracer citrates in oncological models--2. 153Sm-citrate and 67Ga-citrate. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 16: 17-23. PMID 2714996 DOI: 10.1016/0883-2897(89)90210-9 |
0.302 |
|
| 1989 |
Kumar R, Wiebe LI, Hall TW, Knaus EE, Tovell DR, Tyrrell DL, Allen TM, Fathi-Afshar R. Synthesis of 5-[1-hydroxy(or methoxy)-2-bromo(or chloro)ethyl]-2'-deoxyuridines and related halohydrin analogues with antiviral and cytotoxic activity. Journal of Medicinal Chemistry. 32: 941-4. PMID 2709380 DOI: 10.1021/Jm00125A003 |
0.54 |
|
| 1989 |
Somayaji V, Ito S, Jimbow K, Wiebe LI. The synthesis of 4-S-cysteinyl-[U-14C]phenol, an experimental antimelanoma agent. International Journal of Radiation Applications and Instrumentation. Part a, Applied Radiation and Isotopes. 40: 539-40. PMID 2551851 DOI: 10.1016/0883-2889(89)90142-1 |
0.311 |
|
| 1989 |
Mercer JR, Xu LH, Knaus EE, Wiebe LI. Synthesis and tumor uptake of 5-82Br- and 5-131I-labeled 5-halo-1-(2-fluoro-2-deoxy-beta-D-ribofuranosyl)uracils. Journal of Medicinal Chemistry. 32: 1289-94. PMID 2524593 DOI: 10.1021/Jm00126A024 |
0.58 |
|
| 1989 |
Tandon M, Wiebe LI, Knaus EE. Synthesis, separation, and absolute configuration of the two 5-(2,2-dibromocyclopropyl) and four 5-(2-bromocyclopropyl) diastereomers of 2′-deoxyuridine Canadian Journal of Chemistry. 67: 1484-1488. DOI: 10.1139/V89-226 |
0.534 |
|
| 1989 |
Moore SA, Santarsiero BD, Lin T, James MNG, Tandon M, Wiebe LI, Knaus EE. Structure of 1-(2-deoxy-β-D-ribofuranosyl)-5-[(1S)-2,2-dibromocyclopropyl]uracil Acta Crystallographica Section C Crystal Structure Communications. 45: 647-650. DOI: 10.1107/S0108270188012867 |
0.497 |
|
| 1989 |
Somayaji VV, Hall TW, Wiebe LI, Knaus EE, Demers JP. Synthesis of [5-14C]-1,1,12,12-tetraethoxy-4,9-diazadodecane dinitrate Journal of Labelled Compounds and Radiopharmaceuticals. 27: 449-455. DOI: 10.1002/Jlcr.2580270412 |
0.537 |
|
| 1989 |
Tandon M, Xu L, Iwashina T, Tovell D, Knaus E, Tyrrell D, Wiebe L. Synthesis and evaluation of {125I}-(E)-5-(2-iodovinyl)-N3-methyl-2′-deoxy-uridine as a potential probe for the non-invasive diagnosis of herpes simplex encephalitis Journal of Labelled Compounds and Radiopharmaceuticals. 26: 93-94. DOI: 10.1002/Jlcr.2580260141 |
0.513 |
|
| 1988 |
Somayaji VV, Hall TW, Wiebe LI, Knaus EE. An improved synthesis of [1-14C]-labelled 2-butynedioic acid, succinic acid and succinyl chloride Journal of Labelled Compounds and Radiopharmaceuticals. 25: 1325-1331. DOI: 10.1002/Jlcr.2580251206 |
0.532 |
|
| 1987 |
Gati WP, Wiebe LI, Knaus EE, Paterson AR. [125I]iodohydroxynitrobenzylthioinosine: a new high-affinity nucleoside transporter probe. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 65: 467-73. PMID 3620162 DOI: 10.1139/O87-060 |
0.5 |
|
| 1987 |
Tovell DR, Yacyshyn HP, Misra HK, Knaus EE, Wiebe LI, Samuel J, Gill MJ, Tyrrell DL. Effect of acyclovir on the uptake of 131I-labelled 1-(2'fluoro-2'-deoxy-beta-D-arabinofuranosyl)-5-iodouracil in herpes infected cells. Journal of Medical Virology. 22: 183-8. PMID 3039053 DOI: 10.1002/Jmv.1890220210 |
0.547 |
|
| 1987 |
Mercer JR, Knaus EE, Wiebe LI. Synthesis and tumor uptake of 5-halo-1-(2'-fluoro-2'-deoxy-beta-D-ribofuranosyl)[2-14C]uracils. Journal of Medicinal Chemistry. 30: 670-5. PMID 2951522 DOI: 10.1021/Jm00387A015 |
0.571 |
|
| 1987 |
Misra HK, Wiebe LI, Knaus EE. Synthesis of [2-14C]-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-fluoro(chloro)uracil Journal of Labelled Compounds and Radiopharmaceuticals. 24: 1107-1116. DOI: 10.1002/Jlcr.2580240912 |
0.582 |
|
| 1986 |
Wiebe LI, Knaus EE. Drug-induced perturbations in the in vivo distribution of oncological radiotracers--I. 5-Fluoro-6-3H-2'-deoxyuridine influenced by nitrobenzylthioinosine 5'-phosphate (NBMPR-P). International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 13: 257-9. PMID 2945804 DOI: 10.1016/0883-2897(86)90105-4 |
0.529 |
|
| 1986 |
Jette DC, Wiebe LI, Flanagan RJ, Lee J, Chapman JD. Iodoazomycin Riboside (1-(5′-Iodo-5′-Deoxyribofuranosyl)-2-Nitroimidazole), a Hypoxic Cell Marker: I. Synthesis and in Vitro Characterization Radiation Research. 105: 169. DOI: 10.2307/3576542 |
0.308 |
|
| 1986 |
Misra HK, Knaus EE, Wiebe LI, Tyrrell D. Synthesis of 131I, 125I, 123I and 82Br labelled 5-halo-1-(2-deoxy-2-fluoro-β-d-arabinofuranosyl)uracils International Journal of Radiation Applications and Instrumentation. Part a. Applied Radiation and Isotopes. 37: 901-905. DOI: 10.1016/0883-2889(86)90290-X |
0.558 |
|
| 1986 |
Mercer JR, Knaus EE, Wiebe LI. An improved synthesis of 14C-labelled 2,2′-anhydrouridine, 2′-deoxyuridine and 5-ethyl-2′-deoxyuridine International Journal of Radiation Applications and Instrumentation. Part a. Applied Radiation and Isotopes. 37: 613-619. DOI: 10.1016/0883-2889(86)90081-X |
0.54 |
|
| 1985 |
Lee YW, Abrams DN, Wiebe LI, Knaus EE. Tumor uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models--V. 6-[36Cl]chlorouracil, 6-[82Br]bromouracil and 6-[123I]iodouracil. International Journal of Nuclear Medicine and Biology. 11: 262-6. PMID 6549392 DOI: 10.1016/0047-0740(84)90010-X |
0.509 |
|
| 1985 |
Lee YW, Mercer JR, Wiebe LI, Knaus EE. Tumor uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models: VI. 1-(3'-[36Cl]-chloro-, 1-(3'-[82Br]-bromo- and 1-(3'-[123I]-Iodo-3'-deoxy-beta-D-arabinofuranosyl)uracil. The International Journal of Applied Radiation and Isotopes. 35: 1057-61. PMID 6526522 DOI: 10.1016/0020-708X(84)90010-3 |
0.566 |
|
| 1985 |
Lee YW, Mercer JR, Knaus EE, Wiebe LI. The synthesis of [36Cl]-, [82Br]- and [123I]-labelled 1-(3'-chloro-(bromo and iodo)-3'-deoxy-beta-D-arabinofuranosyl)uracil. The International Journal of Applied Radiation and Isotopes. 35: 1053-6. PMID 6526521 DOI: 10.1016/0020-708X(84)90009-7 |
0.558 |
|
| 1985 |
Lee YW, Giziewicz JB, Knaus EE, Wiebe LI. Tumor uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models: VII. [2-14C]-5-ethyl-1-(2'-deoxy-beta-D-ribofuranosyl)uracil. The International Journal of Applied Radiation and Isotopes. 35: 1063-6. PMID 6335492 DOI: 10.1016/0020-708X(84)90011-5 |
0.55 |
|
| 1985 |
Wiebe LI, Flanagan RJ, Helus F, Knapp WH, Knaus EE, Maier-Borst W. Radiolabeled L-fucose for diagnostic oncology: preliminary studies in mice and rats using L-1-14C-fucose. International Journal of Nuclear Medicine and Biology. 12: 111-4. PMID 4044139 DOI: 10.1016/0047-0740(85)90165-2 |
0.527 |
|
| 1985 |
Lee YW, Iwashina T, Gati WP, Knaus EE, Wiebe LI. Tumor uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models--VIII. Synthesis and tissue distribution of N-[2-(hydroxyethoxy) methyl]-5-[3H]methyluracil. The International Journal of Applied Radiation and Isotopes. 36: 395-8. PMID 4018900 DOI: 10.1016/0020-708X(85)90281-9 |
0.538 |
|
| 1985 |
Abrams DN, Mercer JR, Knaus EE, Wiebe LI. The synthesis of radiolabelled 1-(2′-Fluoro-2′-deoxy-β-D-ribofuranosyl)-uracil and 1-(2′-chloro-2′-deoxy-β-D-ribofuranosyl)uracil The International Journal of Applied Radiation and Isotopes. 36: 233-238. DOI: 10.1016/0020-708X(85)90074-2 |
0.583 |
|
| 1985 |
Giziewicz J, Gati LJ, Knaus EE, Mercer JR, Flanagan RJ, Wiebe LI. Synthesis of [2-14C]-labelled 2,2′-anhydrouridine and 2'-deoxyuridine derivatives. A convenient route to [2-14C]-labelled 5-ethynyl- and 5-ethyl-2′-deoxyuridine The International Journal of Applied Radiation and Isotopes. 36: 227-231. DOI: 10.1016/0020-708X(85)90073-0 |
0.56 |
|
| 1984 |
Samuel J, Knaus EE, Wiebe LI, Tyrrell DL. Synthesis of 131I, 125I and 82Br labelled (E)-5-(2-halovinyl)-2'-deoxyuridines. The International Journal of Applied Radiation and Isotopes. 35: 1049-52. PMID 6526520 DOI: 10.1016/0020-708X(84)90008-5 |
0.518 |
|
| 1984 |
Gati WP, Misra HK, Knaus EE, Wiebe LI. Structural modifications at the 2'- and 3'-positions of some pyrimidine nucleosides as determinants of their interaction with the mouse erythrocyte nucleoside transporter. Biochemical Pharmacology. 33: 3325-31. PMID 6497896 DOI: 10.1016/0006-2952(84)90101-1 |
0.522 |
|
| 1984 |
Abrams DN, Lee Y, Knaus EE, Wiebe LI. Synthesis of [6-36Cl]chlorouracil, [6-82Br]bromouracil and [6-123I]iodouracil The International Journal of Applied Radiation and Isotopes. 35: 531-535. DOI: 10.1016/0020-708X(84)90176-5 |
0.533 |
|
| 1984 |
Abrams DN, Knaus EE, Wiebe LI, Helus F, Maier-Borst W. Production of 34m Cl from a gaseous hydrogen sulfide target The International Journal of Applied Radiation and Isotopes. 35: 1045-1048. DOI: 10.1016/0020-708X(84)90007-3 |
0.51 |
|
| 1984 |
Misra HK, Gati WP, Knaus EE, Wiebe LI. Reaction of 1-(2′,3′-epoxy-β-D-lyxofuranosyl)uracil with hydrogen fluoride. The unexpected formation of 1-(3′-fluoro-3′-deoxy-β-D-ribofuranosyl)uracil Journal of Heterocyclic Chemistry. 21: 773-775. DOI: 10.1002/Jhet.5570210327 |
0.558 |
|
| 1983 |
Jette DC, Wiebe LI, Chapman JD. Synthesis and In vivo studies of the radiosensitizer 4-[82Br]bromomisonidazole International Journal of Nuclear Medicine and Biology. 10: 205-210. PMID 6662623 DOI: 10.1016/0047-0740(83)90080-3 |
0.331 |
|
| 1981 |
Abrams DN, Knaus EE, Wiebe LI, Helus F, Maier-Borst W. Tumour uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models--IV. 2'-123I-iodo-2'-deoxyuridine. The International Journal of Applied Radiation and Isotopes. 32: 105-8. PMID 7203701 DOI: 10.1016/0020-708X(81)90142-3 |
0.551 |
|
| 1981 |
Mercer JR, Wiebe LI, Knaus EE. Synthesis of N-(4-pyridyl[14C]carbonylamino)-1,2,[3H]3,6-tetrahydropyridine and the mono-labelled [14C]- and [3H]-analogues Journal of Labelled Compounds and Radiopharmaceuticals. 18: 621-628. DOI: 10.1002/Jlcr.2580180503 |
0.535 |
|
| 1979 |
Abrams DN, Knaus EE, Wiebe LI. Tumor uptake of radiolabeled pyrimidine bases and pyrimidine nucleosides in animal models--I. 6-[3H]-5-fluorouracil. International Journal of Nuclear Medicine and Biology. 6: 97-101. PMID 478772 DOI: 10.1016/0047-0740(79)90003-2 |
0.519 |
|
| 1979 |
Lee YW, Knaus EE, Wiebe LI. Tumor uptake of radiolabeled pyrimidine bases and pyrimidine nucleosides in animal models--III. 2'-[82Br]-bromo-2'-deoxyuridine. International Journal of Nuclear Medicine and Biology. 6: 109-112. PMID 113355 DOI: 10.1016/0047-0740(79)90005-6 |
0.547 |
|
| 1978 |
Mercer JR, Wiebe LI. The synthesis of deuterium labeled butylated hydroxytoluene (BHT) Journal of Labelled Compounds and Radiopharmaceuticals. 14: 445-454. DOI: 10.1002/Jlcr.2580140319 |
0.324 |
|
| Show low-probability matches. |