François Spitz - Publications

EMBL Heidelberg 

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Kaucka M, Petersen J, Tesarova M, Szarowska B, Kastriti ME, Xie M, Kicheva A, Annusver K, Kasper M, Symmons O, Pan L, Spitz F, Kaiser J, Hovorakova M, Zikmund T, et al. Signals from the brain and olfactory epithelium control shaping of the mammalian nasal capsule cartilage. Elife. 7. PMID 29897331 DOI: 10.7554/Elife.34465  1
2018 Bahr C, von Paleske L, Uslu VV, Remeseiro S, Takayama N, Ng SW, Murison A, Langenfeld K, Petretich M, Scognamiglio R, Zeisberger P, Benk AS, Amit I, Zandstra PW, Lupien M, ... ... Spitz F, et al. Author Correction: A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies. Nature. PMID 29769714 DOI: 10.1038/S41586-018-0113-3  0.36
2018 Bahr C, von Paleske L, Uslu VV, Remeseiro S, Takayama N, Ng SW, Murison A, Langenfeld K, Petretich M, Scognamiglio R, Zeisberger P, Benk AS, Amit I, Zandstra PW, Lupien M, ... ... Spitz F, et al. A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies. Nature. PMID 29342133 DOI: 10.1038/Nature25193  0.36
2017 Schwarzer W, Abdennur N, Goloborodko A, Pekowska A, Fudenberg G, Loe-Mie Y, Fonseca NA, Huber W, H Haering C, Mirny L, Spitz F. Two independent modes of chromatin organization revealed by cohesin removal. Nature. 551: 51-56. PMID 29094699 DOI: 10.1038/Nature24281  0.36
2016 Symmons O, Pan L, Remeseiro S, Aktas T, Klein F, Huber W, Spitz F. The Shh Topological Domain Facilitates the Action of Remote Enhancers by Reducing the Effects of Genomic Distances. Developmental Cell. PMID 27867070 DOI: 10.1016/J.Devcel.2016.10.015  1
2016 Franke M, Ibrahim DM, Andrey G, Schwarzer W, Heinrich V, Schöpflin R, Kraft K, Kempfer R, Jerković I, Chan WL, Spielmann M, Timmermann B, Wittler L, Kurth I, Cambiaso P, ... ... Spitz F, et al. Formation of new chromatin domains determines pathogenicity of genomic duplications. Nature. PMID 27706140 DOI: 10.1038/Nature19800  0.6
2016 Yao Y, Minor PJ, Zhao YT, Jeong Y, Pani AM, King AN, Symmons O, Gan L, Cardoso WV, Spitz F, Lowe CJ, Epstein DJ. Erratum: Cis-regulatory architecture of a brain signaling center predates the origin of chordates. Nature Genetics. 48: 970. PMID 27463400 DOI: 10.1038/ng0816-970a  1
2016 Yao Y, Minor PJ, Zhao YT, Jeong Y, Pani AM, King AN, Symmons O, Gan L, Cardoso WV, Spitz F, Lowe CJ, Epstein DJ. Cis-regulatory architecture of a brain signaling center predates the origin of chordates. Nature Genetics. PMID 27064252 DOI: 10.1038/Ng.3542  1
2015 Remeseiro S, Hörnblad A, Spitz F. Gene regulation during development in the light of topologically associating domains. Wiley Interdisciplinary Reviews. Developmental Biology. PMID 26558551 DOI: 10.1002/Wdev.218  1
2015 Liu X, Tamada K, Kishimoto R, Okubo H, Ise S, Ohta H, Ruf S, Nakatani J, Kohno N, Spitz F, Takumi T. Transcriptome profiling of white adipose tissue in a mouse model for 15q duplication syndrome. Genomics Data. 5: 394-6. PMID 26484295 DOI: 10.1016/J.Gdata.2015.06.035  1
2015 Kishimoto R, Tamada K, Liu X, Okubo H, Ise S, Ohta H, Ruf S, Nakatani J, Kohno N, Spitz F, Takumi T. Model mice for 15q11-13 duplication syndrome exhibit late-onset obesity and altered lipid metabolism. Human Molecular Genetics. PMID 26002101 DOI: 10.1093/Hmg/Ddv187  1
2015 Amin S, Donaldson IJ, Zannino DA, Hensman J, Rattray M, Losa M, Spitz F, Ladam F, Sagerström C, Bobola N. Hoxa2 selectively enhances Meis binding to change a branchial arch ground state. Developmental Cell. 32: 265-77. PMID 25640223 DOI: 10.1016/J.Devcel.2014.12.024  1
2015 Tsujimura T, Klein FA, Langenfeld K, Glaser J, Huber W, Spitz F. A discrete transition zone organizes the topological and regulatory autonomy of the adjacent tfap2c and bmp7 genes. Plos Genetics. 11: e1004897. PMID 25569170 DOI: 10.1371/Journal.Pgen.1004897  1
2014 Schwarzer W, Spitz F. The architecture of gene expression: integrating dispersed cis-regulatory modules into coherent regulatory domains. Current Opinion in Genetics & Development. 27: 74-82. PMID 24907448 DOI: 10.1016/J.Gde.2014.03.014  1
2014 Uslu VV, Petretich M, Ruf S, Langenfeld K, Fonseca NA, Marioni JC, Spitz F. Long-range enhancers regulating Myc expression are required for normal facial morphogenesis. Nature Genetics. 46: 753-8. PMID 24859337 DOI: 10.1038/Ng.2971  1
2014 Symmons O, Uslu VV, Tsujimura T, Ruf S, Nassari S, Schwarzer W, Ettwiller L, Spitz F. Functional and topological characteristics of mammalian regulatory domains. Genome Research. 24: 390-400. PMID 24398455 DOI: 10.1101/Gr.163519.113  1
2013 Kirchmaier S, Höckendorf B, Möller EK, Bornhorst D, Spitz F, Wittbrodt J. Efficient site-specific transgenesis and enhancer activity tests in medaka using PhiC31 integrase. Development (Cambridge, England). 140: 4287-95. PMID 24048591 DOI: 10.1242/Dev.096081  1
2013 Andrey G, Montavon T, Mascrez B, Gonzalez F, Noordermeer D, Leleu M, Trono D, Spitz F, Duboule D. A switch between topological domains underlies HoxD genes collinearity in mouse limbs. Science (New York, N.Y.). 340: 1234167. PMID 23744951 DOI: 10.1126/Science.1234167  1
2013 Symmons O, Spitz F. From remote enhancers to gene regulation: charting the genome's regulatory landscapes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20120358. PMID 23650632 DOI: 10.1098/Rstb.2012.0358  1
2013 Chen CK, Symmons O, Uslu VV, Tsujimura T, Ruf S, Smedley D, Spitz F. TRACER: a resource to study the regulatory architecture of the mouse genome. Bmc Genomics. 14: 215. PMID 23547943 DOI: 10.1186/1471-2164-14-215  1
2013 Marini? M, Aktas T, Ruf S, Spitz F. An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape. Developmental Cell. 24: 530-42. PMID 23453598 DOI: 10.1016/J.Devcel.2013.01.025  1
2013 Weischenfeldt J, Symmons O, Spitz F, Korbel JO. Phenotypic impact of genomic structural variation: insights from and for human disease. Nature Reviews. Genetics. 14: 125-38. PMID 23329113 DOI: 10.1038/Nrg3373  1
2012 Spitz F, Furlong EE. Transcription factors: from enhancer binding to developmental control. Nature Reviews. Genetics. 13: 613-26. PMID 22868264 DOI: 10.1038/Nrg3207  1
2011 Montavon T, Soshnikova N, Mascrez B, Joye E, Thevenet L, Splinter E, de Laat W, Spitz F, Duboule D. A regulatory archipelago controls Hox genes transcription in digits. Cell. 147: 1132-45. PMID 22118467 DOI: 10.1016/J.Cell.2011.10.023  1
2011 Ruf S, Symmons O, Uslu VV, Dolle D, Hot C, Ettwiller L, Spitz F. Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor. Nature Genetics. 43: 379-86. PMID 21423180 DOI: 10.1038/Ng.790  1
2010 Friedli M, Barde I, Arcangeli M, Verp S, Quazzola A, Zakany J, Lin-Marq N, Robyr D, Attanasio C, Spitz F, Duboule D, Trono D, Antonarakis SE. A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the Olig1 and Olig2 locus. Plos One. 5: e15741. PMID 21206754 DOI: 10.1371/Journal.Pone.0015741  1
2010 Spitz F. Control of vertebrate Hox clusters by remote and global cis-acting regulatory sequences. Advances in Experimental Medicine and Biology. 689: 63-78. PMID 20795322 DOI: 10.1007/978-1-4419-6673-5_4  1
2010 Rowe HM, Jakobsson J, Mesnard D, Rougemont J, Reynard S, Aktas T, Maillard PV, Layard-Liesching H, Verp S, Marquis J, Spitz F, Constam DB, Trono D. KAP1 controls endogenous retroviruses in embryonic stem cells. Nature. 463: 237-40. PMID 20075919 DOI: 10.1038/Nature08674  1
2009 Tschopp P, Tarchini B, Spitz F, Zakany J, Duboule D. Uncoupling time and space in the collinear regulation of Hox genes. Plos Genetics. 5: e1000398. PMID 19266017 DOI: 10.1371/Journal.Pgen.1000398  1
2008 Ettwiller L, Budd A, Spitz F, Wittbrodt J. Analysis of mammalian gene batteries reveals both stable ancestral cores and highly dynamic regulatory sequences. Genome Biology. 9: R172. PMID 19087242 DOI: 10.1186/Gb-2008-9-12-R172  1
2008 Sauvain MO, Dorr AP, Stevenson B, Quazzola A, Naef F, Wiznerowicz M, Schütz F, Jongeneel V, Duboule D, Spitz F, Trono D. Genotypic features of lentivirus transgenic mice. Journal of Virology. 82: 7111-9. PMID 18463153 DOI: 10.1128/Jvi.00623-08  1
2008 Friedli M, Nikolaev S, Lyle R, Arcangeli M, Duboule D, Spitz F, Antonarakis SE. Characterization of mouse Dactylaplasia mutations: a model for human ectrodactyly SHFM3. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 19: 272-8. PMID 18392654 DOI: 10.1007/S00335-008-9106-0  1
2008 Spitz F, Duboule D. Global control regions and regulatory landscapes in vertebrate development and evolution. Advances in Genetics. 61: 175-205. PMID 18282506 DOI: 10.1016/S0065-2660(07)00006-5  1
2007 Gonzalez F, Duboule D, Spitz F. Transgenic analysis of Hoxd gene regulation during digit development. Developmental Biology. 306: 847-59. PMID 17448461 DOI: 10.1016/J.Ydbio.2007.03.020  1
2006 Spitz F, Furlong EE. Genomics and development: Taking developmental biology to new heights. Developmental Cell. 11: 451-7. PMID 17051688 DOI: 10.1016/J.Devcel.2006.09.013  1
2006 Spitz F, Herkenne C, Hinard C, Duboule D. [A STRING lifts the veil on the mechanisms controlling Hox genes expression]. MéDecine Sciences : M/S. 22: 14-6. PMID 16386210 DOI: 10.1051/Medsci/200622114  1
2005 Spitz F, Herkenne C, Morris MA, Duboule D. Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes. Nature Genetics. 37: 889-93. PMID 15995706 DOI: 10.1038/Ng1597  1
2005 Spitz F, Duboule D. Developmental biology: reproduction in clusters. Nature. 434: 715-6. PMID 15815616 DOI: 10.1038/434715A  1
2004 Grifone R, Laclef C, Spitz F, Lopez S, Demignon J, Guidotti JE, Kawakami K, Xu PX, Kelly R, Petrof BJ, Daegelen D, Concordet JP, Maire P. Six1 and Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotype. Molecular and Cellular Biology. 24: 6253-67. PMID 15226428 DOI: 10.1128/Mcb.24.14.6253-6267.2004  1
2004 Zuniga A, Michos O, Spitz F, Haramis AP, Panman L, Galli A, Vintersten K, Klasen C, Mansfield W, Kuc S, Duboule D, Dono R, Zeller R. Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression. Genes & Development. 18: 1553-64. PMID 15198975 DOI: 10.1101/Gad.299904  1
2004 Spitz F. [Genes without borders: global control of transcription activity at the level of several genes]. MéDecine Sciences : M/S. 20: 9-10. PMID 14770355 DOI: 10.1051/Medsci/20042019  1
2003 Spitz F, Gonzalez F, Duboule D. A global control region defines a chromosomal regulatory landscape containing the HoxD cluster. Cell. 113: 405-17. PMID 12732147 DOI: 10.1016/S0092-8674(03)00310-6  1
2002 Spitz F, Benbacer L, Sabourin JC, Salminen M, Chen F, Cywiner C, Kahn A, Chatelet F, Maire P, Daegelen D. Fiber-type specific and position-dependent expression of a transgene in limb muscles. Differentiation; Research in Biological Diversity. 70: 457-67. PMID 12366383 DOI: 10.1046/J.1432-0436.2002.700808.X  1
2002 Spitz F, Montavon T, Monso-Hinard C, Morris M, Ventruto ML, Antonarakis S, Ventruto V, Duboule D. A t(2;8) balanced translocation with breakpoints near the human HOXD complex causes mesomelic dysplasia and vertebral defects. Genomics. 79: 493-8. PMID 11944980 DOI: 10.1006/Geno.2002.6735  1
2001 Spitz F, Gonzalez F, Peichel C, Vogt TF, Duboule D, Zákány J. Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations. Genes & Development. 15: 2209-14. PMID 11544178 DOI: 10.1101/Gad.205701  1
2001 Spitz F, Duboule D. Development. The art of making a joint. Science (New York, N.Y.). 291: 1713-4. PMID 11253195 DOI: 10.1126/Science.1059665  0.88
2001 Spitz F, Duboule D. The art of making a joint Science. 291: 1713-1714. DOI: 10.1126/science.1059665  1
2000 Fan X, Brass LF, Poncz M, Spitz F, Maire P, Manning DR. The alpha subunits of Gz and Gi interact with the eyes absent transcription cofactor Eya2, preventing its interaction with the six class of homeodomain-containing proteins. The Journal of Biological Chemistry. 275: 32129-34. PMID 10906137 DOI: 10.1074/Jbc.M004577200  1
1999 Spitz F, Demignon J, Kahn A, Daegelen D, Maire P. Developmental regulation of the aldolase A muscle-specific promoter during in vivo muscle maturation is controlled by a nuclear receptor binding element. Journal of Molecular Biology. 289: 893-903. PMID 10369770 DOI: 10.1006/Jmbi.1999.2821  1
1998 Spitz F, Demignon J, Porteu A, Kahn A, Concordet JP, Daegelen D, Maire P. Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site. Proceedings of the National Academy of Sciences of the United States of America. 95: 14220-5. PMID 9826681 DOI: 10.1073/Pnas.95.24.14220  1
1998 Spitz F, De Vasconcelos ZA, Châtelet F, Demignon J, Kahn A, Mira JC, Maire P, Daegelen D. Proximal sequences of the aldolase A fast muscle-specific promoter direct nerve- and activity-dependent expression in transgenic mice. The Journal of Biological Chemistry. 273: 14975-81. PMID 9614104 DOI: 10.1074/Jbc.273.24.14975  1
1998 Moch C, Spitz F, Porteu A, Kahn A, Daegelen D. The human pH aldolase A promoter directs widespread but muscle-predominant expression in transgenic mice. Transgenic Research. 7: 113-21. PMID 9608739 DOI: 10.1023/A:1008820409079  1
1998 Spitz F, Demignon J, Demeurie J, Sabourin JC, Kahn A, Daegelen D, Maire P. A binding site for nuclear receptors is required for the differential expression of the aldolase A fast-twitch muscle promoter in body and head muscles. The Journal of Biological Chemistry. 273: 561-7. PMID 9417116 DOI: 10.1074/Jbc.273.1.561  1
1997 Spitz F, Salminen M, Demignon J, Kahn A, Daegelen D, Maire P. A combination of MEF3 and NFI proteins activates transcription in a subset of fast-twitch muscles. Molecular and Cellular Biology. 17: 656-66. PMID 9001219 DOI: 10.1128/Mcb.17.2.656  1
1997 Maire P, Spitz F. As | Muscles de la tête, muscles des jambes et muscles du tronc, demandez le programme myogénique! Medecine/Sciences. 13: 1182-1186.  1
1995 Salminen M, Spitz F, Fiszman MY, Demignon J, Kahn A, Daegelen D, Maire P. Myotube-specific activity of the human aldolase A M-promoter requires an overlapping binding site for NF1 and MEF2 factors in addition to a binding site (M1) for unknown proteins. Journal of Molecular Biology. 253: 17-31. PMID 7473711 DOI: 10.1006/Jmbi.1995.0532  1
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