| Year |
Citation |
Score |
| 2023 |
Pan B, Gardner SM, Schultz K, Perez RM, Deng S, Shimogawa M, Sato K, Rhoades E, Marmorstein R, Petersson EJ. Semi-Synthetic CoA-α-Synuclein Constructs Trap N-Terminal Acetyltransferase NatB for Binding Mechanism Studies. Journal of the American Chemical Society. 145: 14019-14030. PMID 37319422 DOI: 10.1021/jacs.3c03887 |
0.326 |
|
| 2023 |
Wei X, Schultz K, Pepper HL, Megill E, Vogt A, Snyder NW, Marmorstein R. Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nature Communications. 14: 2247. PMID 37076498 DOI: 10.1038/s41467-023-37986-9 |
0.795 |
|
| 2023 |
Pan B, Gardner S, Schultz K, Perez RM, Deng S, Shimogawa M, Sato K, Rhoades E, Marmorstein R, Petersson EJ. Semi-synthetic CoA-α-Synuclein Constructs Trap N-terminal Acetyltransferase NatB for Binding Mechanism Studies. Biorxiv : the Preprint Server For Biology. PMID 37066334 DOI: 10.1101/2023.04.03.535351 |
0.327 |
|
| 2023 |
Deng S, Gardner SM, Gottlieb L, Pan B, Petersson EJ, Marmorstein R. Molecular role of NAA38 in thermostability and catalytic activity of the human NatC N-terminal acetyltransferase. Structure (London, England : 1993). 31: 166-173.e4. PMID 36638802 DOI: 10.1016/j.str.2022.12.008 |
0.304 |
|
| 2022 |
Ricketts MD, Emptage RP, Blobel GA, Marmorstein R. The Heme-Regulated Inhibitor Kinase Requires Dimerization for Heme- Sensing Activity. The Journal of Biological Chemistry. 102451. PMID 36063997 DOI: 10.1016/j.jbc.2022.102451 |
0.333 |
|
| 2022 |
Wei X, Kixmoeller K, Baltrusaitis E, Yang X, Marmorstein R. Allosteric role of a structural NADP molecule in glucose-6-phosphate dehydrogenase activity. Proceedings of the National Academy of Sciences of the United States of America. 119: e2119695119. PMID 35858355 DOI: 10.1073/pnas.2119695119 |
0.784 |
|
| 2021 |
Wei X, Marmorstein R. Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase. Nature Structural & Molecular Biology. PMID 34294921 DOI: 10.1038/s41594-021-00625-2 |
0.757 |
|
| 2021 |
Deng Y, Deng S, Ho YH, Gardner SM, Huang Z, Marmorstein R, Huang R. Novel Bisubstrate Inhibitors for Protein N-Terminal Acetyltransferase D. Journal of Medicinal Chemistry. PMID 34110812 DOI: 10.1021/acs.jmedchem.1c00141 |
0.323 |
|
| 2021 |
Deng S, Gottlieb L, Pan B, Supplee J, Wei X, Petersson EJ, Marmorstein R. Molecular mechanism of N-terminal acetylation by the ternary NatC complex. Structure (London, England : 1993). PMID 34019809 DOI: 10.1016/j.str.2021.05.003 |
0.801 |
|
| 2021 |
Ji Z, Clark RF, Bhat V, Matthew Hansen T, Lasko LM, Bromberg KD, Manaves V, Algire M, Martin R, Qiu W, Torrent M, Jakob CG, Liu H, Cole PA, Marmorstein R, et al. Discovery of Spirohydantoins as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases. Bioorganic & Medicinal Chemistry Letters. 127854. PMID 33631370 DOI: 10.1016/j.bmcl.2021.127854 |
0.316 |
|
| 2020 |
Nguyen D, Lin LY, Zhou JO, Kibby E, Sia TW, Tillis TD, Vapuryan N, Xu MR, Potluri R, Shin Y, Erler EA, Bronkema N, Boehlmer DJ, Chung CD, Burkhard C, ... ... Marmorstein R, et al. Identification and Characterization of a B-Raf Kinase α-Helix Critical for the Activity of MEK Kinase in MAPK Signaling. Biochemistry. PMID 33272017 DOI: 10.1021/acs.biochem.0c00598 |
0.727 |
|
| 2020 |
Deng S, Marmorstein R. Protein N-Terminal Acetylation: Structural Basis, Mechanism, Versatility, and Regulation. Trends in Biochemical Sciences. PMID 32912665 DOI: 10.1016/J.Tibs.2020.08.005 |
0.442 |
|
| 2020 |
Deng S, Pan B, Gottlieb L, Petersson J, Marmorstein R. Molecular basis for N-terminal alpha-synuclein acetylation by human NatB. Elife. 9. PMID 32885784 DOI: 10.7554/Elife.57491 |
0.43 |
|
| 2020 |
Wei X, Schultz K, Bazilevsky GA, Vogt A, Marmorstein R. Author Correction: Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nature Structural & Molecular Biology. PMID 32242119 DOI: 10.1038/S41594-020-0421-9 |
0.756 |
|
| 2020 |
Deng S, McTiernan N, Wei X, Arnesen T, Marmorstein R. Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK. Nature Communications. 11: 818. PMID 32042062 DOI: 10.1038/S41467-020-14584-7 |
0.815 |
|
| 2020 |
Cheng H, Gottlieb L, Marchi E, Kleyner R, Bhardwaj P, Rope AF, Rosenheck S, Moutton S, Philippe C, Eyaid W, Alkuraya FS, Toribio J, Mena R, Prada CE, Stessman H, ... ... Marmorstein R, et al. Phenotypic and biochemical analysis of an international cohort of individuals with variants in NAA10 and NAA15. Human Molecular Genetics. PMID 32027362 DOI: 10.1093/Hmg/Ddz173 |
0.336 |
|
| 2020 |
Wei X, Schultz K, Bazilevsky G, Vogt A, Marmorstein R. Molecular Basis for Acetyl‐CoA Production by ATP‐Citrate Lyase The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.08807 |
0.737 |
|
| 2020 |
Szurgot M, Marmorstein R. Molecular Characterization of the HIRA Histone Chaperone Complex from Chaetomium thermophilum The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02110 |
0.374 |
|
| 2019 |
Wei X, Schultz K, Bazilevsky GA, Vogt A, Marmorstein R. Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nature Structural & Molecular Biology. PMID 31873304 DOI: 10.2210/Pdb6Poe/Pdb |
0.803 |
|
| 2019 |
Song S, Perez JV, Svitko W, Ricketts MD, Dean E, Schultz D, Marmorstein R, Johnson FB. Rap1-mediated nucleosome displacement can regulate gene expression in senescent cells without impacting the pace of senescence. Aging Cell. e13061. PMID 31742863 DOI: 10.1111/Acel.13061 |
0.395 |
|
| 2019 |
Gottlieb L, Marmorstein R. Biochemical and structural analysis of N-terminal acetyltransferases. Methods in Enzymology. 626: 271-299. PMID 31606079 DOI: 10.1016/Bs.Mie.2019.07.016 |
0.438 |
|
| 2019 |
Deng S, Magin RS, Wei X, Pan B, Petersson EJ, Marmorstein R. Structure and Mechanism of Acetylation by the N-Terminal Dual Enzyme NatA/Naa50 Complex. Structure (London, England : 1993). PMID 31155310 DOI: 10.1016/J.Str.2019.04.014 |
0.804 |
|
| 2019 |
Ricketts MD, Dasgupta N, Fan J, Han J, Gerace M, Tang Y, Black BE, Adams PD, Marmorstein R. The HIRA histone chaperone complex subunit UBN1 harbors H3/H4 and DNA binding activity. The Journal of Biological Chemistry. PMID 31040182 DOI: 10.1074/Jbc.Ra119.007480 |
0.372 |
|
| 2019 |
Bazilevsky GA, Affronti HC, Wei X, Campbell SL, Wellen KE, Marmorstein R. ATP-citrate lyase multimerization is required for coenzyme-A substrate binding and catalysis. The Journal of Biological Chemistry. PMID 30877197 DOI: 10.1074/Jbc.Ra118.006685 |
0.807 |
|
| 2018 |
Rebecca VW, Nicastri MC, Fennelly C, Chude CI, Barber-Rotenberg JS, Ronghe A, McAfee Q, McLaughlin NP, Zhang G, Goldman AR, Ojha R, Piao S, Noguera-Ortega E, Martorella A, Alicea GM, ... ... Marmorstein R, et al. PPT1 promotes tumor growth and is the molecular target of chloroquine derivatives in cancer. Cancer Discovery. PMID 30442709 DOI: 10.1158/2159-8290.Cd-18-0706 |
0.773 |
|
| 2018 |
Ricketts MD, Han J, Szurgot M, Marmorstein R. Molecular basis for chromatin assembly and modification by multi-protein complexes. Protein Science : a Publication of the Protein Society. PMID 30350439 DOI: 10.1002/Pro.3535 |
0.455 |
|
| 2018 |
Emptage RP, Lemmon MA, Ferguson KM, Marmorstein R. Structural Basis for MARK1 Kinase Autoinhibition by Its KA1 Domain. Structure (London, England : 1993). 26: 1137-1143.e3. PMID 30099988 DOI: 10.1016/J.Str.2018.05.008 |
0.65 |
|
| 2018 |
Arnesen T, Marmorstein R, Dominguez R. Actin's N-terminal acetyltransferase uncovered. Cytoskeleton (Hoboken, N.J.). PMID 30084538 DOI: 10.1002/Cm.21455 |
0.342 |
|
| 2018 |
Ray-Gallet D, Ricketts MD, Sato Y, Gupta K, Boyarchuk E, Senda T, Marmorstein R, Almouzni G. Functional activity of the H3.3 histone chaperone complex HIRA requires trimerization of the HIRA subunit. Nature Communications. 9: 3103. PMID 30082790 DOI: 10.1038/S41467-018-05581-Y |
0.431 |
|
| 2018 |
Cope N, Candelora C, Wong K, Kumar S, Nan H, Grasso M, Novak B, Li Y, Marmorstein R, Wang Z. Mechanism of BRAF Activation Through Biochemical Characterization of the Recombinant Full-Length Protein. Chembiochem : a European Journal of Chemical Biology. PMID 29992710 DOI: 10.1002/Cbic.201800359 |
0.403 |
|
| 2018 |
Gottlieb L, Marmorstein R. Structure of Human NatA and Its Regulation by the Huntingtin Interacting Protein HYPK. Structure (London, England : 1993). PMID 29754825 DOI: 10.1016/J.Str.2018.04.003 |
0.481 |
|
| 2018 |
Grasso M, Estrada MA, Berrios KN, Winkler JD, Marmorstein R. N-{7-Cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]acetyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide (TAK632) promotes inhibition of BRAF through the induction of inhibited dimers. Journal of Medicinal Chemistry. PMID 29727562 DOI: 10.1021/Acs.Jmedchem.8B00499 |
0.405 |
|
| 2018 |
Goris M, Magin RS, Foyn H, Myklebust LM, Varland S, Ree R, Drazic A, Bhambra P, Støve SI, Baumann M, Haug BE, Marmorstein R, Arnesen T. Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581307 DOI: 10.2210/Pdb5Wjd/Pdb |
0.437 |
|
| 2018 |
Mawhinney MT, Liu R, Lu F, Maksimoska J, Damico K, Marmorstein R, Lieberman PM, Urbanc B. CTCF-Induced Circular DNA Complexes Observed by Atomic Force Microscopy. Journal of Molecular Biology. PMID 29409905 DOI: 10.1016/J.Jmb.2018.01.012 |
0.764 |
|
| 2018 |
Han J, Lachance C, Ricketts MD, McCullough CE, Gerace M, Black BE, Côté J, Marmorstein R. The scaffolding protein JADE1 physically links the acetyltransferase subunit HBO1 with its histone H3/H4 substrate. The Journal of Biological Chemistry. PMID 29382722 DOI: 10.1074/Jbc.Ra117.000677 |
0.466 |
|
| 2018 |
Michaelides MR, Kluge A, Patane M, Van Drie JH, Wang C, Hansen TM, Risi RM, Mantei R, Hertel C, Karukurichi K, Nesterov A, McElligott D, de Vries P, Langston JW, Cole PA, ... Marmorstein R, et al. Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases. Acs Medicinal Chemistry Letters. 9: 28-33. PMID 29348807 DOI: 10.1021/Acsmedchemlett.7B00395 |
0.436 |
|
| 2017 |
Simithy J, Sidoli S, Yuan ZF, Coradin M, Bhanu NV, Marchione DM, Klein BJ, Bazilevsky GA, McCullough CE, Magin RS, Kutateladze TG, Snyder NW, Marmorstein R, Garcia BA. Characterization of histone acylations links chromatin modifications with metabolism. Nature Communications. 8: 1141. PMID 29070843 DOI: 10.1038/S41467-017-01384-9 |
0.396 |
|
| 2017 |
Magin RS, Deng S, Zhang H, Cooperman B, Marmorstein R. Probing the interaction between NatA and the ribosome for co-translational protein acetylation. Plos One. 12: e0186278. PMID 29016658 DOI: 10.1371/Journal.Pone.0186278 |
0.442 |
|
| 2017 |
Emptage RP, Schoenberger MJ, Ferguson KM, Marmorstein R. Intramolecular autoinhibition of Checkpoint Kinase 1 is mediated by conserved basic motifs of the C-terminal Kinase Associated-1 domain. The Journal of Biological Chemistry. PMID 28972186 DOI: 10.1074/Jbc.M117.811265 |
0.651 |
|
| 2017 |
Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T, ... ... Marmorstein R, et al. Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours. Nature. PMID 28953875 DOI: 10.1038/Nature24028 |
0.466 |
|
| 2017 |
Rebecca VW, Nicastri MC, McLaughlin N, Fennelly C, McAfee Q, Ronghe A, Nofal M, Lim CY, Witze E, Chude CI, Zhang G, Alicea GM, Piao S, Murugan S, Ojha R, ... ... Marmorstein R, et al. A unified approach to targeting the lysosome's degradative and growth signaling roles. Cancer Discovery. PMID 28899863 DOI: 10.1158/2159-8290.Cd-17-0741 |
0.779 |
|
| 2017 |
Marmorstein R, Adams PD. Epigenetics meets metabolism through PHB-mediated histone H3.3 deposition by HIRA. Stem Cell Investigation. 4: 46. PMID 28607920 DOI: 10.21037/Sci.2017.05.08 |
0.432 |
|
| 2016 |
Feng Z, Wang L, Sun Y, Jiang Z, Domsic J, An C, Xing B, Tian J, Liu X, Metz DC, Yang X, Marmorstein R, Ma X, Hua X. Menin and Daxx Interact to Control Neuroendocrine Tumors via Epigenetic Regulation of Membrane Metallo-Endopeptidase. Cancer Research. PMID 27872097 DOI: 10.1158/0008-5472.Can-16-1567 |
0.357 |
|
| 2016 |
Ricketts MD, Marmorstein R. A molecular prospective for HIRA complex assembly and H3.3-specific histone chaperone function. Journal of Molecular Biology. PMID 27871933 DOI: 10.1016/J.Jmb.2016.11.010 |
0.408 |
|
| 2016 |
Rivera-Colón Y, Maguire A, Liszczak GP, Olia AS, Marmorstein R. Molecular Basis for Cohesin Acetylation by Establishment of Sister Chromatid Cohesion N-acetyltransferase ESCO1. The Journal of Biological Chemistry. PMID 27803161 DOI: 10.1016/J.Bpj.2015.11.2931 |
0.823 |
|
| 2016 |
Grasso M, Estrada MA, Ventocilla C, Samanta M, Maksimoska J, Villanueva J, Winkler JD, Marmorstein R. Chemically Linked Vemurafenib Inhibitors Promote an Inactive BRAFV600E Conformation. Acs Chemical Biology. PMID 27571413 DOI: 10.1021/Acschembio.6B00529 |
0.777 |
|
| 2016 |
Rong Z, Ouyang Z, Magin RS, Marmorstein R, Yu H. Opposing Functions of the N-terminal Acetyltransferases Naa50 and NatA in Sister-chromatid Cohesion. The Journal of Biological Chemistry. PMID 27422821 DOI: 10.1074/Jbc.M116.737585 |
0.363 |
|
| 2016 |
Mccullough CE, Song S, Shin MH, Johnson FB, Marmorstein R. Structural and Functional Role of Acetyltransferase hMOF K274 Autoacetylation. The Journal of Biological Chemistry. PMID 27382063 DOI: 10.1074/Jbc.M116.736264 |
0.425 |
|
| 2016 |
McCullough CE, Marmorstein R. In Vitro Activity Assays for MYST Histone Acetyltransferases and Adaptation for High-Throughput Inhibitor Screening. Methods in Enzymology. 573: 139-60. PMID 27372752 DOI: 10.1016/Bs.Mie.2016.01.016 |
0.438 |
|
| 2016 |
Støve SI, Magin RS, Foyn H, Haug BE, Marmorstein R, Arnesen T. Crystal Structure of the Golgi-Associated Human Nα-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation. Structure (London, England : 1993). PMID 27320834 DOI: 10.1016/J.Str.2016.04.020 |
0.494 |
|
| 2016 |
Shirakawa K, Wang L, Man N, Maksimoska J, Sorum AW, Lim HW, Lee IS, Shimazu T, Newman JC, Schröder S, Ott M, Marmorstein R, Meier J, Nimer S, Verdin E. Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity. Elife. 5. PMID 27244239 DOI: 10.7554/Elife.11156 |
0.778 |
|
| 2016 |
Margin RS, March ZM, Marmorstein R. The N-terminal acetyltransferase Naa10/ARD1 does not acetylate lysine residues. The Journal of Biological Chemistry. PMID 26755727 DOI: 10.1074/Jbc.M115.709428 |
0.469 |
|
| 2016 |
Shirakawa K, Wang L, Man N, Maksimoska J, Sorum AW, Lim HW, Lee IS, Shimazu T, Newman JC, Schröder S, Ott M, Marmorstein R, Meier J, Nimer S, Verdin E. Author response: Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity Elife. DOI: 10.7554/Elife.11156.014 |
0.735 |
|
| 2015 |
Ndubaku CO, Crawford JJ, Drobnick J, Aliagas I, Campbell D, Dong P, Dornan LM, Duron S, Epler J, Gazzard L, Heise CE, Hoeflich KP, Jakubiak D, La H, Lee W, ... ... Marmorstein R, et al. Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety. Acs Medicinal Chemistry Letters. 6: 1241-6. PMID 26713112 DOI: 10.1021/Acsmedchemlett.5B00398 |
0.752 |
|
| 2015 |
Mccullough CE, Marmorstein R. Molecular basis for histone acetyltransferase regulation by binding partners, associated domains, and autoacetylation. Acs Chemical Biology. PMID 26555232 DOI: 10.1021/Acschembio.5B00841 |
0.449 |
|
| 2015 |
Haigney A, Ricketts MD, Marmorstein R. Dissecting the Molecular Roles of Histone Chaperones in Histone Acetylation by Type B Histone Acetyltransferases (HAT-B). The Journal of Biological Chemistry. PMID 26522166 DOI: 10.1074/Jbc.M115.688523 |
0.413 |
|
| 2015 |
Marmorstein R, Simon MC. Structural biology: Hypoxia response becomes crystal clear. Nature. 524: 298-300. PMID 26245369 DOI: 10.1038/Nature14641 |
0.371 |
|
| 2015 |
Daniel Ricketts M, Frederick B, Hoff H, Tang Y, Schultz DC, Singh Rai T, Grazia Vizioli M, Adams PD, Marmorstein R. Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex. Nature Communications. 6: 7711. PMID 26159857 DOI: 10.1038/Ncomms8711 |
0.397 |
|
| 2015 |
Olia AS, Barker K, McCullough CE, Tang HY, Speicher DW, Qiu J, LaBaer J, Marmorstein R. Nonenzymatic Protein Acetylation Detected by NAPPA Protein Arrays. Acs Chemical Biology. PMID 26083674 DOI: 10.1021/Acschembio.5B00342 |
0.422 |
|
| 2015 |
Magin RS, Liszczak GP, Marmorstein R. The molecular basis for histone H4- and H2A-specific amino-terminal acetylation by NatD. Structure (London, England : 1993). 23: 332-41. PMID 25619998 DOI: 10.1016/J.Str.2014.10.025 |
0.806 |
|
| 2015 |
Myklebust LM, Van Damme P, Støve SI, Dörfel MJ, Abboud A, Kalvik TV, Grauffel C, Jonckheere V, Wu Y, Swensen J, Kaasa H, Liszczak G, Marmorstein R, Reuter N, Lyon GJ, et al. Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects. Human Molecular Genetics. 24: 1956-76. PMID 25489052 DOI: 10.1093/Hmg/Ddu611 |
0.765 |
|
| 2015 |
Qin J, Rajaratnam R, Feng L, Salami J, Barber-Rotenberg JS, Domsic J, Reyes-Uribe P, Liu H, Dang W, Berger SL, Villanueva J, Meggers E, Marmorstein R. Development of organometallic S6K1 inhibitors. Journal of Medicinal Chemistry. 58: 305-14. PMID 25356520 DOI: 10.1021/Jm5011868 |
0.809 |
|
| 2015 |
Ndubaku CO, Crawford JJ, Drobnick J, Aliagas I, Campbell D, Dong P, Dornan LM, Duron S, Epler J, Gazzard L, Heise CE, Hoeflich KP, Jakubiak D, La H, Lee W, ... ... Marmorstein R, et al. Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pKa Polar Moiety Acs Medicinal Chemistry Letters. 6: 1241-1246. DOI: 10.1021/acsmedchemlett.5b00398 |
0.708 |
|
| 2014 |
Tsai K, Chan L, Gibeault R, Conn K, Dheekollu J, Domsic J, Marmorstein R, Schang LM, Lieberman PM. Viral reprogramming of the Daxx histone H3.3 chaperone during early Epstein-Barr virus infection. Journal of Virology. 88: 14350-63. PMID 25275136 DOI: 10.1128/Jvi.01895-14 |
0.361 |
|
| 2014 |
Leu JI, Zhang P, Murphy ME, Marmorstein R, George DL. Structural basis for the inhibition of HSP70 and DnaK chaperones by small-molecule targeting of a C-terminal allosteric pocket. Acs Chemical Biology. 9: 2508-16. PMID 25148104 DOI: 10.1021/Cb500236Y |
0.418 |
|
| 2014 |
Zhang P, Leu JI, Murphy ME, George DL, Marmorstein R. Crystal structure of the stress-inducible human heat shock protein 70 substrate-binding domain in complex with peptide substrate. Plos One. 9: e103518. PMID 25058147 DOI: 10.1371/Journal.Pone.0103518 |
0.44 |
|
| 2014 |
Marmorstein R, Zhou MM. Writers and readers of histone acetylation: structure, mechanism, and inhibition. Cold Spring Harbor Perspectives in Biology. 6: a018762. PMID 24984779 DOI: 10.1101/cshperspect.a018762 |
0.426 |
|
| 2014 |
Malecka KA, Fera D, Schultz DC, Hodawadekar S, Reichman M, Donover PS, Murphy ME, Marmorstein R. Identification and characterization of small molecule human papillomavirus E6 inhibitors. Acs Chemical Biology. 9: 1603-12. PMID 24854633 DOI: 10.1021/Cb500229D |
0.773 |
|
| 2014 |
Maksimoska J, Segura-Peña D, Cole PA, Marmorstein R. Structure of the p300 histone acetyltransferase bound to acetyl-coenzyme A and its analogues. Biochemistry. 53: 3415-22. PMID 24819397 DOI: 10.1021/Bi500380F |
0.805 |
|
| 2014 |
Zhang X, Ouyang S, Kong X, Liang Z, Lu J, Zhu K, Zhao D, Zheng M, Jiang H, Liu X, Marmorstein R, Luo C. Catalytic mechanism of histone acetyltransferase p300: from the proton transfer to acetylation reaction. The Journal of Physical Chemistry. B. 118: 2009-19. PMID 24521098 DOI: 10.1021/Jp409778E |
0.35 |
|
| 2014 |
Plasschaert RN, Vigneau S, Tempera I, Gupta R, Maksimoska J, Everett L, Davuluri R, Marmorstein R, Lieberman PM, Schultz D, Hannenhalli S, Bartolomei MS. CTCF binding site sequence differences are associated with unique regulatory and functional trends during embryonic stem cell differentiation Nucleic Acids Research. 42: 7487-7487. DOI: 10.1093/Nar/Gku470 |
0.737 |
|
| 2013 |
Taylor MS, Ruch TR, Hsiao PY, Hwang Y, Zhang P, Dai L, Huang CR, Berndsen CE, Kim MS, Pandey A, Wolberger C, Marmorstein R, Machamer C, Boeke JD, Cole PA. Architectural organization of the metabolic regulatory enzyme ghrelin O-acyltransferase. The Journal of Biological Chemistry. 288: 32211-28. PMID 24045953 DOI: 10.1074/Jbc.M113.510313 |
0.623 |
|
| 2013 |
Licciulli S, Maksimoska J, Zhou C, Troutman S, Kota S, Liu Q, Duron S, Campbell D, Chernoff J, Field J, Marmorstein R, Kissil JL. FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas. The Journal of Biological Chemistry. 288: 29105-14. PMID 23960073 DOI: 10.1074/Jbc.M113.510933 |
0.773 |
|
| 2013 |
Liszczak G, Marmorstein R. Implications for the evolution of eukaryotic amino-terminal acetyltransferase (NAT) enzymes from the structure of an archaeal ortholog. Proceedings of the National Academy of Sciences of the United States of America. 110: 14652-7. PMID 23959863 DOI: 10.1073/Pnas.1310365110 |
0.789 |
|
| 2013 |
Liszczak G, Goldberg JM, Foyn H, Petersson EJ, Arnesen T, Marmorstein R. Molecular basis for N-terminal acetylation by the heterodimeric NatA complex. Nature Structural & Molecular Biology. 20: 1098-105. PMID 23912279 DOI: 10.1038/Nsmb.2636 |
0.801 |
|
| 2013 |
Friedmann DR, Marmorstein R. Structure and mechanism of non-histone protein acetyltransferase enzymes. The Febs Journal. 280: 5570-81. PMID 23742047 DOI: 10.1111/Febs.12373 |
0.353 |
|
| 2013 |
Yuan H, Marmorstein R. Biochemistry. Red wine, toast of the town (again). Science (New York, N.Y.). 339: 1156-7. PMID 23471392 DOI: 10.1126/Science.1236463 |
0.361 |
|
| 2013 |
Yuan H, Marmorstein R. Histone acetyltransferases: Rising ancient counterparts to protein kinases. Biopolymers. 99: 98-111. PMID 23175385 DOI: 10.1002/Bip.22128 |
0.453 |
|
| 2013 |
Abshiru N, Ippersiel K, Tang Y, Yuan H, Marmorstein R, Verreault A, Thibault P. Chaperone-mediated acetylation of histones by Rtt109 identified by quantitative proteomics. Journal of Proteomics. 81: 80-90. PMID 23036725 DOI: 10.1016/J.Jprot.2012.09.026 |
0.355 |
|
| 2012 |
Grauffel C, Abboud A, Liszczak G, Marmorstein R, Arnesen T, Reuter N. Specificity and versatility of substrate binding sites in four catalytic domains of human N-terminal acetyltransferases. Plos One. 7: e52642. PMID 23285125 DOI: 10.1371/Journal.Pone.0052642 |
0.795 |
|
| 2012 |
Fera D, Marmorstein R. Different regions of the HPV-E7 and Ad-E1A viral oncoproteins bind competitively but through distinct mechanisms to the CH1 transactivation domain of p300. Biochemistry. 51: 9524-34. PMID 23121466 DOI: 10.1021/Bi3011863 |
0.735 |
|
| 2012 |
Yuan H, Marmorstein R. Structural basis for sirtuin activity and inhibition. The Journal of Biological Chemistry. 287: 42428-35. PMID 23086949 DOI: 10.1074/Jbc.R112.372300 |
0.42 |
|
| 2012 |
Friedmann DR, Aguilar A, Fan J, Nachury MV, Marmorstein R. Structure of the α-tubulin acetyltransferase, αTAT1, and implications for tubulin-specific acetylation. Proceedings of the National Academy of Sciences of the United States of America. 109: 19655-60. PMID 23071314 DOI: 10.1073/Pnas.1209357109 |
0.499 |
|
| 2012 |
Qin J, Xie P, Ventocilla C, Zhou G, Vultur A, Chen Q, Liu Q, Herlyn M, Winkler J, Marmorstein R. Identification of a novel family of BRAF(V600E) inhibitors. Journal of Medicinal Chemistry. 55: 5220-30. PMID 22537109 DOI: 10.1021/Jm3004416 |
0.49 |
|
| 2012 |
Fera D, Schultz DC, Hodawadekar S, Reichman M, Donover PS, Melvin J, Troutman S, Kissil JL, Huryn DM, Marmorstein R. Identification and characterization of small molecule antagonists of pRb inactivation by viral oncoproteins. Chemistry & Biology. 19: 518-28. PMID 22520758 DOI: 10.1016/J.Chembiol.2012.03.007 |
0.718 |
|
| 2012 |
Tang Y, Puri A, Ricketts MD, Rai TS, Hoffmann J, Hoi E, Adams PD, Schultz DC, Marmorstein R. Identification of an ubinuclein 1 region required for stability and function of the human HIRA/UBN1/CABIN1/ASF1a histone H3.3 chaperone complex. Biochemistry. 51: 2366-77. PMID 22401310 DOI: 10.1021/Bi300050B |
0.438 |
|
| 2012 |
Blanck S, Maksimoska J, Baumeister J, Harms K, Marmorstein R, Meggers E. The art of filling protein pockets efficiently with octahedral metal complexes. Angewandte Chemie (International Ed. in English). 51: 5244-6. PMID 22383326 DOI: 10.1002/Anie.201108865 |
0.803 |
|
| 2012 |
Pan M, Yuan H, Brent M, Ding EC, Marmorstein R. SIRT1 contains N- and C-terminal regions that potentiate deacetylase activity. The Journal of Biological Chemistry. 287: 2468-76. PMID 22157016 DOI: 10.1074/Jbc.M111.285031 |
0.633 |
|
| 2012 |
Yuan H, Rossetto D, Mellert H, Dang W, Srinivasan M, Johnson J, Hodawadekar S, Ding EC, Speicher K, Abshiru N, Perry R, Wu J, Yang C, Zheng YG, Speicher DW, ... ... Marmorstein R, et al. MYST protein acetyltransferase activity requires active site lysine autoacetylation. The Embo Journal. 31: 58-70. PMID 22020126 DOI: 10.1038/Emboj.2011.382 |
0.364 |
|
| 2012 |
Blanck S, Maksimoska J, Baumeister J, Harms K, Marmorstein R, Meggers E. Effizientes Ausfüllen von Proteintaschen mit oktaedrischen Metallkomplexen Angewandte Chemie. 124: 5335-5338. DOI: 10.1002/Ange.201108865 |
0.727 |
|
| 2011 |
Liszczak G, Arnesen T, Marmorstein R. Structure of a ternary Naa50p (NAT5/SAN) N-terminal acetyltransferase complex reveals the molecular basis for substrate-specific acetylation. The Journal of Biological Chemistry. 286: 37002-10. PMID 21900231 DOI: 10.1074/Jbc.M111.282863 |
0.807 |
|
| 2011 |
Yi C, Troutman S, Fera D, Stemmer-Rachamimov A, Avila JL, Christian N, Persson NL, Shimono A, Speicher DW, Marmorstein R, Holmgren L, Kissil JL. A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions. Cancer Cell. 19: 527-40. PMID 21481793 DOI: 10.1016/J.Ccr.2011.02.017 |
0.738 |
|
| 2011 |
Feng L, Geisselbrecht Y, Blanck S, Wilbuer A, Atilla-Gokcumen GE, Filippakopoulos P, Kräling K, Celik MA, Harms K, Maksimoska J, Marmorstein R, Frenking G, Knapp S, Essen LO, Meggers E. Structurally sophisticated octahedral metal complexes as highly selective protein kinase inhibitors. Journal of the American Chemical Society. 133: 5976-86. PMID 21446733 DOI: 10.1021/Ja1112996 |
0.802 |
|
| 2011 |
Tang Y, Holbert MA, Delgoshaie N, Wurtele H, Guillemette B, Meeth K, Yuan H, Drogaris P, Lee EH, Durette C, Thibault P, Verreault A, Cole PA, Marmorstein R. Structure of the Rtt109-AcCoA/Vps75 complex and implications for chaperone-mediated histone acetylation. Structure (London, England : 1993). 19: 221-31. PMID 21256037 DOI: 10.1016/J.Str.2010.12.012 |
0.781 |
|
| 2011 |
Streu C, Feng L, Carroll PJ, Maksimoska J, Marmorstein R, Meggers E. P-donor ligand containing ruthenium half-sandwich complexes as protein kinase inhibitors Inorganica Chimica Acta. 377: 34-41. DOI: 10.1016/J.Ica.2011.07.032 |
0.814 |
|
| 2010 |
Huang R, Holbert MA, Tarrant MK, Curtet S, Colquhoun DR, Dancy BM, Dancy BC, Hwang Y, Tang Y, Meeth K, Marmorstein R, Cole RN, Khochbin S, Cole PA. Site-specific introduction of an acetyl-lysine mimic into peptides and proteins by cysteine alkylation. Journal of the American Chemical Society. 132: 9986-7. PMID 20608637 DOI: 10.1021/Ja103954U |
0.785 |
|
| 2010 |
Bowers EM, Yan G, Mukherjee C, Orry A, Wang L, Holbert MA, Crump NT, Hazzalin CA, Liszczak G, Yuan H, Larocca C, Saldanha SA, Abagyan R, Sun Y, Meyers DJ, ... Marmorstein R, et al. Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor. Chemistry & Biology. 17: 471-82. PMID 20534345 DOI: 10.1016/J.Chembiol.2010.03.006 |
0.813 |
|
| 2010 |
Yi C, Maksimoska J, Marmorstein R, Kissil JL. Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer. Biochemical Pharmacology. 80: 683-9. PMID 20302846 DOI: 10.1016/J.Bcp.2010.03.012 |
0.756 |
|
| 2010 |
Ipsaro JJ, Harper SL, Messick TE, Marmorstein R, Mondragón A, Speicher DW. Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex. Blood. 115: 4843-52. PMID 20197550 DOI: 10.1182/Blood-2010-01-261396 |
0.572 |
|
| 2010 |
Sanders BD, Jackson B, Marmorstein R. Structural basis for sirtuin function: what we know and what we don't. Biochimica Et Biophysica Acta. 1804: 1604-16. PMID 19766737 DOI: 10.1016/J.Bbapap.2009.09.009 |
0.663 |
|
| 2009 |
Sanders BD, Jackson B, Brent M, Taylor AM, Dang W, Berger SL, Schreiber SL, Howitz K, Marmorstein R. Identification and characterization of novel sirtuin inhibitor scaffolds. Bioorganic & Medicinal Chemistry. 17: 7031-41. PMID 19734050 DOI: 10.1016/J.Bmc.2009.07.073 |
0.71 |
|
| 2009 |
Hait NC, Allegood J, Maceyka M, Strub GM, Harikumar KB, Singh SK, Luo C, Marmorstein R, Kordula T, Milstien S, Spiegel S. Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. Science (New York, N.Y.). 325: 1254-7. PMID 19729656 DOI: 10.1126/science.1176709 |
0.3 |
|
| 2009 |
Brent MM, Iwata A, Carten J, Zhao K, Marmorstein R. Structure and biochemical characterization of protein acetyltransferase from Sulfolobus solfataricus. The Journal of Biological Chemistry. 284: 19412-9. PMID 19473964 DOI: 10.1074/Jbc.M109.014951 |
0.705 |
|
| 2009 |
Xie P, Streu C, Qin J, Bregman H, Pagano N, Meggers E, Marmorstein R. The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase. Biochemistry. 48: 5187-98. PMID 19371126 DOI: 10.1021/Bi802067U |
0.627 |
|
| 2009 |
Anand R, Maksimoska J, Pagano N, Wong EY, Gimotty PA, Diamond SL, Meggers E, Marmorstein R. Toward the development of a potent and selective organoruthenium mammalian sterile 20 kinase inhibitor. Journal of Medicinal Chemistry. 52: 1602-11. PMID 19226137 DOI: 10.1021/Jm8005806 |
0.794 |
|
| 2009 |
Banumathy G, Somaiah N, Zhang R, Tang Y, Hoffmann J, Andrake M, Ceulemans H, Schultz D, Marmorstein R, Adams PD. Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells. Molecular and Cellular Biology. 29: 758-70. PMID 19029251 DOI: 10.1128/MCB.01047-08 |
0.357 |
|
| 2009 |
Malecka KA, Ho WC, Marmorstein R. Crystal structure of a p53 core tetramer bound to DNA. Oncogene. 28: 325-33. PMID 18978813 DOI: 10.1038/Onc.2008.400 |
0.809 |
|
| 2009 |
Marmorstein R, Trievel RC. Histone modifying enzymes: structures, mechanisms, and specificities. Biochimica Et Biophysica Acta. 1789: 58-68. PMID 18722564 DOI: 10.1016/j.bbagrm.2008.07.009 |
0.689 |
|
| 2008 |
Maksimoska J, Feng L, Harms K, Yi C, Kissil J, Marmorstein R, Meggers E. Targeting large kinase active site with rigid, bulky octahedral ruthenium complexes. Journal of the American Chemical Society. 130: 15764-5. PMID 18973295 DOI: 10.1021/Ja805555A |
0.804 |
|
| 2008 |
Wang L, Tang Y, Cole PA, Marmorstein R. Structure and chemistry of the p300/CBP and Rtt109 histone acetyltransferases: implications for histone acetyltransferase evolution and function. Current Opinion in Structural Biology. 18: 741-7. PMID 18845255 DOI: 10.1016/J.Sbi.2008.09.004 |
0.468 |
|
| 2008 |
Brent MM, Anand R, Marmorstein R. Structural basis for DNA recognition by FoxO1 and its regulation by posttranslational modification. Structure (London, England : 1993). 16: 1407-16. PMID 18786403 DOI: 10.1016/J.Str.2008.06.013 |
0.615 |
|
| 2008 |
Luo C, Xie P, Marmorstein R. Identification of BRAF inhibitors through in silico screening. Journal of Medicinal Chemistry. 51: 6121-7. PMID 18783202 DOI: 10.1021/Jm800539G |
0.49 |
|
| 2008 |
Tang Y, Meeth K, Jiang E, Luo C, Marmorstein R. Structure of Vps75 and implications for histone chaperone function. Proceedings of the National Academy of Sciences of the United States of America. 105: 12206-11. PMID 18723682 DOI: 10.1073/Pnas.0802393105 |
0.478 |
|
| 2008 |
Hong M, Fitzgerald MX, Harper S, Luo C, Speicher DW, Marmorstein R. Structural basis for dimerization in DNA recognition by Gal4. Structure (London, England : 1993). 16: 1019-26. PMID 18611375 DOI: 10.1016/J.Str.2008.03.015 |
0.706 |
|
| 2008 |
Tang Y, Holbert MA, Wurtele H, Meeth K, Rocha W, Gharib M, Jiang E, Thibault P, Verreault A, Verrault A, Cole PA, Marmorstein R. Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP. Nature Structural & Molecular Biology. 15: 738-45. PMID 18568037 DOI: 10.1038/Nsmb.1448 |
0.812 |
|
| 2008 |
Anand R, Kim AY, Brent M, Marmorstein R. Biochemical analysis of MST1 kinase: elucidation of a C-terminal regulatory region. Biochemistry. 47: 6719-26. PMID 18510339 DOI: 10.1021/Bi800309M |
0.631 |
|
| 2008 |
Xie P, Williams DS, Atilla-Gokcumen GE, Milk L, Xiao M, Smalley KS, Herlyn M, Meggers E, Marmorstein R. Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity. Acs Chemical Biology. 3: 305-16. PMID 18484710 DOI: 10.1021/Cb800039Y |
0.593 |
|
| 2008 |
Kwon HS, Brent MM, Getachew R, Jayakumar P, Chen LF, Schnolzer M, McBurney MW, Marmorstein R, Greene WC, Ott M. Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation. Cell Host & Microbe. 3: 158-67. PMID 18329615 DOI: 10.1016/J.Chom.2008.02.002 |
0.561 |
|
| 2008 |
Brent MM, Marmorstein R. Ankyrin for methylated lysines. Nature Structural & Molecular Biology. 15: 221-2. PMID 18319736 DOI: 10.1038/Nsmb0308-221 |
0.631 |
|
| 2008 |
Liu X, Wang L, Zhao K, Thompson PR, Hwang Y, Marmorstein R, Cole PA. The structural basis of protein acetylation by the p300/CBP transcriptional coactivator. Nature. 451: 846-50. PMID 18273021 DOI: 10.1038/Nature06546 |
0.488 |
|
| 2008 |
Messick TE, Russell NS, Iwata AJ, Sarachan KL, Shiekhattar R, Shanks JR, Reyes-Turcu FE, Wilkinson KD, Marmorstein R. Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein. The Journal of Biological Chemistry. 283: 11038-49. PMID 18270205 DOI: 10.1074/Jbc.M704398200 |
0.462 |
|
| 2008 |
Walter W, Clynes D, Tang Y, Marmorstein R, Mellor J, Berger SL. 14-3-3 interaction with histone H3 involves a dual modification pattern of phosphoacetylation. Molecular and Cellular Biology. 28: 2840-9. PMID 18268010 DOI: 10.1128/Mcb.01457-07 |
0.352 |
|
| 2008 |
Tang Y, Holbert MA, Wurtele H, Meeth K, Rocha W, Gharib M, Jiang E, Thibault P, Verreault A, Cole PA, Marmorstein R. Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP (Nature Structural and Molecular Biology (2008) 15, (738-745)) Nature Structural and Molecular Biology. 15: 998. DOI: 10.1038/Nsmb0908-998D |
0.773 |
|
| 2007 |
Liu X, Marmorstein R. Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor. Genes & Development. 21: 2711-6. PMID 17974914 DOI: 10.1101/Gad.1590607 |
0.5 |
|
| 2007 |
Holbert MA, Sikorski T, Carten J, Snowflack D, Hodawadekar S, Marmorstein R. The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targeting. The Journal of Biological Chemistry. 282: 36603-13. PMID 17925393 DOI: 10.1074/Jbc.M705812200 |
0.781 |
|
| 2007 |
Anand R, Marmorstein R. Structure and mechanism of lysine-specific demethylase enzymes. The Journal of Biological Chemistry. 282: 35425-9. PMID 17897944 DOI: 10.1074/Jbc.R700027200 |
0.441 |
|
| 2007 |
Hodawadekar SC, Marmorstein R. Chemistry of acetyl transfer by histone modifying enzymes: structure, mechanism and implications for effector design. Oncogene. 26: 5528-40. PMID 17694092 DOI: 10.1038/sj.onc.1210619 |
0.365 |
|
| 2007 |
Li K, Ossareh-Nazari B, Liu X, Dargemont C, Marmorstein R. Molecular basis for bre5 cofactor recognition by the ubp3 deubiquitylating enzyme. Journal of Molecular Biology. 372: 194-204. PMID 17632125 DOI: 10.1016/J.Jmb.2007.06.052 |
0.524 |
|
| 2007 |
Karanam B, Wang L, Wang D, Liu X, Marmorstein R, Cotter R, Cole PA. Multiple roles for acetylation in the interaction of p300 HAT with ATF-2. Biochemistry. 46: 8207-16. PMID 17590016 DOI: 10.1021/Bi7000054 |
0.516 |
|
| 2007 |
Sanders BD, Zhao K, Slama JT, Marmorstein R. Structural basis for nicotinamide inhibition and base exchange in Sir2 enzymes. Molecular Cell. 25: 463-72. PMID 17289592 DOI: 10.1016/J.Molcel.2006.12.022 |
0.683 |
|
| 2006 |
Sykes SM, Mellert HS, Holbert MA, Li K, Marmorstein R, Lane WS, McMahon SB. Acetylation of the p53 DNA-binding domain regulates apoptosis induction. Molecular Cell. 24: 841-51. PMID 17189187 DOI: 10.1016/J.Molcel.2006.11.026 |
0.75 |
|
| 2006 |
Ho WC, Luo C, Zhao K, Chai X, Fitzgerald MX, Marmorstein R. High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds. Acta Crystallographica. Section D, Biological Crystallography. 62: 1484-93. PMID 17139084 DOI: 10.1107/S090744490603890X |
0.728 |
|
| 2006 |
Wilson JM, Le VQ, Zimmerman C, Marmorstein R, Pillus L. Nuclear export modulates the cytoplasmic Sir2 homologue Hst2. Embo Reports. 7: 1247-51. PMID 17110954 DOI: 10.1038/Sj.Embor.7400829 |
0.386 |
|
| 2006 |
Tang Y, Poustovoitov MV, Zhao K, Garfinkel M, Canutescu A, Dunbrack R, Adams PD, Marmorstein R. Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly. Nature Structural & Molecular Biology. 13: 921-9. PMID 16980972 DOI: 10.1038/Nsmb1147 |
0.356 |
|
| 2006 |
Liu X, Marmorstein R. When viral oncoprotein meets tumor suppressor: a structural view. Genes & Development. 20: 2332-7. PMID 16951249 DOI: 10.1101/Gad.1471706 |
0.379 |
|
| 2006 |
Ho WC, Fitzgerald MX, Marmorstein R. Structure of the p53 core domain dimer bound to DNA. The Journal of Biological Chemistry. 281: 20494-502. PMID 16717092 DOI: 10.1074/Jbc.M603634200 |
0.729 |
|
| 2006 |
Fitzgerald MX, Rojas JR, Kim JM, Kohlhaw GB, Marmorstein R. Structure of a Leu3-DNA complex: recognition of everted CGG half-sites by a Zn2Cys6 binuclear cluster protein. Structure (London, England : 1993). 14: 725-35. PMID 16615914 DOI: 10.1016/J.Str.2005.11.025 |
0.783 |
|
| 2006 |
Culhane JC, Szewczuk LM, Liu X, Da G, Marmorstein R, Cole PA. A mechanism-based inactivator for histone demethylase LSD1. Journal of the American Chemical Society. 128: 4536-7. PMID 16594666 DOI: 10.1021/Ja0602748 |
0.809 |
|
| 2006 |
Nayak V, Zhao K, Wyce A, Schwartz MF, Lo WS, Berger SL, Marmorstein R. Structure and dimerization of the kinase domain from yeast Snf1, a member of the Snf1/AMPK protein family. Structure (London, England : 1993). 14: 477-85. PMID 16531232 DOI: 10.1016/J.Str.2005.12.008 |
0.629 |
|
| 2006 |
Da G, Lenkart J, Zhao K, Shiekhattar R, Cairns BR, Marmorstein R. Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes. Proceedings of the National Academy of Sciences of the United States of America. 103: 2057-62. PMID 16461455 DOI: 10.1073/Pnas.0510949103 |
0.827 |
|
| 2006 |
Liu X, Clements A, Zhao K, Marmorstein R. Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor. The Journal of Biological Chemistry. 281: 578-86. PMID 16249186 DOI: 10.1074/Jbc.M508455200 |
0.392 |
|
| 2005 |
Holbert MA, Marmorstein R. Structure and activity of enzymes that remove histone modifications. Current Opinion in Structural Biology. 15: 673-80. PMID 16263263 DOI: 10.1016/J.Sbi.2005.10.006 |
0.777 |
|
| 2005 |
Wang W, Ho WC, Dicker DT, MacKinnon C, Winkler JD, Marmorstein R, El-Deiry WS. Acridine derivatives activate p53 and induce tumor cell death through Bax. Cancer Biology & Therapy. 4: 893-8. PMID 16177561 DOI: 10.4161/Cbt.4.8.2134 |
0.594 |
|
| 2005 |
Li K, Zhao K, Ossareh-Nazari B, Da G, Dargemont C, Marmorstein R. Structural basis for interaction between the Ubp3 deubiquitinating enzyme and its Bre5 cofactor. The Journal of Biological Chemistry. 280: 29176-85. PMID 15955808 DOI: 10.1074/Jbc.M502975200 |
0.826 |
|
| 2005 |
Deng Z, Atanasiu C, Zhao K, Marmorstein R, Sbodio JI, Chi NW, Lieberman PM. Inhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1. Journal of Virology. 79: 4640-50. PMID 15795250 DOI: 10.1128/Jvi.79.8.4640-4650.2005 |
0.31 |
|
| 2004 |
Marmorstein R. Structure and chemistry of the Sir2 family of NAD+-dependent histone/protein deactylases. Biochemical Society Transactions. 32: 904-9. PMID 15506920 DOI: 10.1042/Bst0320904 |
0.499 |
|
| 2004 |
Marmorstein R. Structural and chemical basis of histone acetylation. Novartis Foundation Symposium. 259: 78-98; discussion 98. PMID 15171248 |
0.376 |
|
| 2004 |
Zhao K, Harshaw R, Chai X, Marmorstein R. Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases. Proceedings of the National Academy of Sciences of the United States of America. 101: 8563-8. PMID 15150415 DOI: 10.1073/pnas.0401057101 |
0.385 |
|
| 2004 |
Zhao K, Chai X, Marmorstein R. Structure and substrate binding properties of cobB, a Sir2 homolog protein deacetylase from Escherichia coli. Journal of Molecular Biology. 337: 731-41. PMID 15019790 DOI: 10.1016/J.Jmb.2004.01.060 |
0.505 |
|
| 2004 |
Marmorstein R. Biochemical and structural characterization of recombinant histone acetyltransferase proteins. Methods in Enzymology. 376: 106-19. PMID 14975301 DOI: 10.1016/S0076-6879(03)76007-8 |
0.328 |
|
| 2003 |
Clements A, Marmorstein R. Insights into structure and function of GCN5/PCAF and yEsa 1 histone acetyltransferase domains:. Methods in Enzymology. 371: 545-64. PMID 14712728 DOI: 10.1016/S0076-6879(03)71041-6 |
0.487 |
|
| 2003 |
Poux AN, Marmorstein R. Molecular basis for Gcn5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates. Biochemistry. 42: 14366-74. PMID 14661947 DOI: 10.1021/Bi035632N |
0.825 |
|
| 2003 |
Marmorstein R. Transcription initiation at its most basic level. Cell. 115: 370-2. PMID 14622590 DOI: 10.1016/S0092-8674(03)00888-2 |
0.366 |
|
| 2003 |
Zhao K, Chai X, Marmorstein R. Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-acetyl ADP ribose and histone peptide. Structure (London, England : 1993). 11: 1403-11. PMID 14604530 DOI: 10.1016/J.Str.2003.09.016 |
0.49 |
|
| 2003 |
Clements A, Poux AN, Lo WS, Pillus L, Berger SL, Marmorstein R. Structural basis for histone and phosphohistone binding by the GCN5 histone acetyltransferase. Molecular Cell. 12: 461-73. PMID 14536085 DOI: 10.1016/S1097-2765(03)00288-0 |
0.823 |
|
| 2003 |
Zhao K, Chai X, Clements A, Marmorstein R. Structure and autoregulation of the yeast Hst2 homolog of Sir2. Nature Structural Biology. 10: 864-71. PMID 14502267 DOI: 10.1038/Nsb978 |
0.469 |
|
| 2003 |
Zhao K, Chai X, Marmorstein R. Structure of a Sir2 substrate, Alba, reveals a mechanism for deacetylation-induced enhancement of DNA binding. The Journal of Biological Chemistry. 278: 26071-7. PMID 12730210 DOI: 10.1074/Jbc.M303666200 |
0.494 |
|
| 2003 |
Xiao B, Spencer J, Clements A, Ali-Khan N, Mittnacht S, Broceño C, Burghammer M, Perrakis A, Marmorstein R, Gamblin SJ. Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation. Proceedings of the National Academy of Sciences of the United States of America. 100: 2363-8. PMID 12598654 DOI: 10.1073/Pnas.0436813100 |
0.464 |
|
| 2003 |
Marmorstein R. Structure of SET domain proteins: a new twist on histone methylation. Trends in Biochemical Sciences. 28: 59-62. PMID 12575990 DOI: 10.1016/S0968-0004(03)00007-0 |
0.461 |
|
| 2003 |
Marmorstein R, Fitzgerald MX. Modulation of DNA-binding domains for sequence-specific DNA recognition. Gene. 304: 1-12. PMID 12568710 DOI: 10.1016/S0378-1119(02)01207-6 |
0.578 |
|
| 2002 |
Marmorstein R. Dehydrogenases, NAD, and transcription--what's the connection? Structure (London, England : 1993). 10: 1465-6. PMID 12429083 DOI: 10.1016/S0969-2126(02)00887-0 |
0.397 |
|
| 2002 |
Poux AN, Cebrat M, Kim CM, Cole PA, Marmorstein R. Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 99: 14065-70. PMID 12391296 DOI: 10.1073/Pnas.222373899 |
0.838 |
|
| 2002 |
Venkataramani RN, MacLachlan TK, Chai X, El-Deiry WS, Marmorstein R. Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity. The Journal of Biological Chemistry. 277: 48827-33. PMID 12370184 DOI: 10.1074/Jbc.M208061200 |
0.805 |
|
| 2002 |
Yan Y, Harper S, Speicher DW, Marmorstein R. The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate. Nature Structural Biology. 9: 862-9. PMID 12368900 DOI: 10.1038/Nsb849 |
0.629 |
|
| 2001 |
Mo Y, Ho W, Johnston K, Marmorstein R. Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex. Journal of Molecular Biology. 314: 495-506. PMID 11846562 DOI: 10.1006/Jmbi.2001.5138 |
0.701 |
|
| 2001 |
Marmorstein R. Structure of histone deacetylases: insights into substrate recognition and catalysis. Structure (London, England : 1993). 9: 1127-33. PMID 11738039 DOI: 10.1016/S0969-2126(01)00690-6 |
0.447 |
|
| 2001 |
Marmorstein R. Structure of histone acetyltransferases. Journal of Molecular Biology. 311: 433-44. PMID 11492997 DOI: 10.1006/Jmbi.2001.4859 |
0.501 |
|
| 2001 |
Marmorstein R, Berger SL. Structure and function of bromodomains in chromatin-regulating complexes. Gene. 272: 1-9. PMID 11470504 DOI: 10.1016/S0378-1119(01)00519-4 |
0.383 |
|
| 2001 |
Marmorstein R. Structure and function of histone acetyltransferases. Cellular and Molecular Life Sciences : Cmls. 58: 693-703. PMID 11437231 |
0.448 |
|
| 2001 |
Marmorstein R. Protein modules that manipulate histone tails for chromatin regulation. Nature Reviews. Molecular Cell Biology. 2: 422-32. PMID 11389466 DOI: 10.1038/35073047 |
0.313 |
|
| 2001 |
Marmorstein R, Roth SY. Histone acetyltransferases: function, structure, and catalysis. Current Opinion in Genetics & Development. 11: 155-61. PMID 11250138 DOI: 10.1016/S0959-437X(00)00173-8 |
0.34 |
|
| 2001 |
Zhao K, Chai X, Johnston K, Clements A, Marmorstein R. Crystal structure of the mouse p53 core DNA-binding domain at 2.7 A resolution. The Journal of Biological Chemistry. 276: 12120-7. PMID 11152481 DOI: 10.1074/Jbc.M011644200 |
0.425 |
|
| 2000 |
Trievel RC, Li FY, Marmorstein R. Application of a fluorescent histone acetyltransferase assay to probe the substrate specificity of the human p300/CBP-associated factor. Analytical Biochemistry. 287: 319-28. PMID 11112280 DOI: 10.1006/Abio.2000.4855 |
0.72 |
|
| 2000 |
Yan Y, Barlev NA, Haley RH, Berger SL, Marmorstein R. Crystal structure of yeast Esa1 suggests a unified mechanism for catalysis and substrate binding by histone acetyltransferases. Molecular Cell. 6: 1195-205. PMID 11106757 DOI: 10.1016/S1097-2765(00)00116-7 |
0.655 |
|
| 2000 |
Johnston K, Clements A, Venkataramani RN, Trievel RC, Marmorstein R. Coexpression of proteins in bacteria using T7-based expression plasmids: expression of heteromeric cell-cycle and transcriptional regulatory complexes. Protein Expression and Purification. 20: 435-43. PMID 11087683 DOI: 10.1006/Prep.2000.1313 |
0.768 |
|
| 2000 |
Lukens AK, King DA, Marmorstein R. Structure of HAP1-PC7 bound to DNA: implications for DNA recognition and allosteric effects of DNA-binding on transcriptional activation. Nucleic Acids Research. 28: 3853-63. PMID 11024163 DOI: 10.1093/Nar/28.20.3853 |
0.391 |
|
| 2000 |
Lo WS, Trievel RC, Rojas JR, Duggan L, Hsu JY, Allis CD, Marmorstein R, Berger SL. Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14. Molecular Cell. 5: 917-26. PMID 10911986 DOI: 10.1016/S1097-2765(00)80257-9 |
0.813 |
|
| 2000 |
Mo Y, Vaessen B, Johnston K, Marmorstein R. Structure of the elk-1-DNA complex reveals how DNA-distal residues affect ETS domain recognition of DNA. Nature Structural Biology. 7: 292-7. PMID 10742173 DOI: 10.1038/74055 |
0.59 |
|
| 2000 |
Rojas JR, Yan Y, Trievel RC, Clements A, Zhou J, Barlev N, Lo W, Sterner D, Wang L, Berger SL, Allis CD, Marmorstein R. Structure of the Histone Acetyltransferase Domains of the GCN5, P/CAF and ESA1 Transcriptional Coactivators Biochemical Society Transactions. 28: A106-A106. DOI: 10.1042/Bst028A106 |
0.818 |
|
| 1999 |
Li X, Peng H, Schultz DC, Lopez-Guisa JM, Rauscher FJ, Marmorstein R. Structure-function studies of the BTB/POZ transcriptional repression domain from the promyelocytic leukemia zinc finger oncoprotein. Cancer Research. 59: 5275-82. PMID 10537309 DOI: 10.2210/Pdb1Cs3/Pdb |
0.598 |
|
| 1999 |
Rojas JR, Trievel RC, Zhou J, Mo Y, Li X, Berger SL, Allis CD, Marmorstein R. Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide. Nature. 401: 93-8. PMID 10485713 DOI: 10.1038/43487 |
0.842 |
|
| 1999 |
Trievel RC, Rojas JR, Sterner DE, Venkataramani RN, Wang L, Zhou J, Allis CD, Berger SL, Marmorstein R. Crystal structure and mechanism of histone acetylation of the yeast GCN5 transcriptional coactivator. Proceedings of the National Academy of Sciences of the United States of America. 96: 8931-6. PMID 10430873 DOI: 10.1073/Pnas.96.16.8931 |
0.819 |
|
| 1999 |
Clements A, Rojas JR, Trievel RC, Wang L, Berger SL, Marmorstein R. Crystal structure of the histone acetyltransferase domain of the human PCAF transcriptional regulator bound to coenzyme A. The Embo Journal. 18: 3521-32. PMID 10393169 DOI: 10.1093/Emboj/18.13.3521 |
0.847 |
|
| 1999 |
Tanner KG, Trievel RC, Kuo MH, Howard RM, Berger SL, Allis CD, Marmorstein R, Denu JM. Catalytic mechanism and function of invariant glutamic acid 173 from the histone acetyltransferase GCN5 transcriptional coactivator. The Journal of Biological Chemistry. 274: 18157-60. PMID 10373413 DOI: 10.1074/jbc.274.26.18157 |
0.691 |
|
| 1999 |
Liu L, Scolnick DM, Trievel RC, Zhang HB, Marmorstein R, Halazonetis TD, Berger SL. p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage. Molecular and Cellular Biology. 19: 1202-9. PMID 9891054 DOI: 10.1128/Mcb.19.2.1202 |
0.663 |
|
| 1999 |
King DA, Zhang L, Guarente L, Marmorstein R. Structure of a HAP1-DNA complex reveals dramatically asymmetric DNA binding by a homodimeric protein. Nature Structural Biology. 6: 64-71. PMID 9886294 DOI: 10.1038/4940 |
0.415 |
|
| 1999 |
King DA, Zhang L, Guarente L, Marmorstein R. Structure of HAP1-18-DNA implicates direct allosteric effect of protein-DNA interactions on transcriptional activation. Nature Structural Biology. 6: 22-7. PMID 9886287 DOI: 10.1038/4893 |
0.409 |
|
| 1998 |
Mo Y, Vaessen B, Johnston K, Marmorstein R. Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins. Molecular Cell. 2: 201-12. PMID 9734357 DOI: 10.1016/S1097-2765(00)80130-6 |
0.577 |
|
| 1998 |
Venkataramani R, Swaminathan K, Marmorstein R. Crystal structure of the CDK4/6 inhibitory protein p18INK4c provides insights into ankyrin-like repeat structure/function and tumor-derived p16INK4 mutations. Nature Structural Biology. 5: 74-81. PMID 9437433 DOI: 10.1038/Nsb0198-74 |
0.809 |
|
| 1997 |
Li X, Lopez-Guisa JM, Ninan N, Weiner EJ, Rauscher FJ, Marmorstein R. Overexpression, purification, characterization, and crystallization of the BTB/POZ domain from the PLZF oncoprotein. The Journal of Biological Chemistry. 272: 27324-9. PMID 9341182 DOI: 10.1074/Jbc.272.43.27324 |
0.584 |
|
| 1997 |
Swaminathan K, Flynn P, Reece RJ, Marmorstein R. Crystal structure of a PUT3-DNA complex reveals a novel mechanism for DNA recognition by a protein containing a Zn2Cys6 binuclear cluster. Nature Structural Biology. 4: 751-9. PMID 9303004 DOI: 10.1038/Nsb0997-751 |
0.364 |
|
| 1996 |
Liang SD, Marmorstein R, Harrison SC, Ptashne M. DNA sequence preferences of GAL4 and PPR1: how a subset of Zn2 Cys6 binuclear cluster proteins recognizes DNA. Molecular and Cellular Biology. 16: 3773-80. PMID 8668194 DOI: 10.1128/Mcb.16.7.3773 |
0.468 |
|
| 1994 |
Marmorstein R, Harrison SC. Crystal structure of a PPR1-DNA complex: DNA recognition by proteins containing a Zn2Cys6 binuclear cluster. Genes & Development. 8: 2504-12. PMID 7958913 DOI: 10.1101/Gad.8.20.2504 |
0.521 |
|
| 1992 |
Baleja JD, Marmorstein R, Harrison SC, Wagner G. Solution structure of the DNA-binding domain of Cd2-GAL4 from S. cerevisiae. Nature. 356: 450-3. PMID 1557130 DOI: 10.1038/356450A0 |
0.506 |
|
| 1992 |
Marmorstein R, Carey M, Ptashne M, Harrison SC. DNA recognition by GAL4: structure of a protein-DNA complex. Nature. 356: 408-14. PMID 1557122 DOI: 10.1038/356408A0 |
0.532 |
|
| 1991 |
Marmorstein RQ, Sprinzl M, Sigler PB. An alkaline phosphatase protection assay to investigate trp repressor/operator interactions. Biochemistry. 30: 1141-8. PMID 1989682 |
0.544 |
|
| 1989 |
Marmorstein RQ, Sigler PB. Stereochemical effects of L-tryptophan and its analogues on trp repressor's affinity for operator-DNA. The Journal of Biological Chemistry. 264: 9149-54. PMID 2656696 |
0.541 |
|
| 1988 |
Otwinowski Z, Schevitz RW, Zhang RG, Lawson CL, Joachimiak A, Marmorstein RQ, Luisi BF, Sigler PB. Crystal structure of trp repressor/operator complex at atomic resolution. Nature. 335: 321-9. PMID 3419502 DOI: 10.1038/335321a0 |
0.753 |
|
| 1987 |
Marmorstein RQ, Joachimiak A, Sprinzl M, Sigler PB. The structural basis for the interaction between L-tryptophan and the Escherichia coli trp aporepressor. The Journal of Biological Chemistry. 262: 4922-7. PMID 3549712 |
0.52 |
|
| 1987 |
Joachimiak A, Marmorstein RQ, Schevitz RW, Mandecki W, Fox JL, Sigler PB. Crystals of the trp repressor-operator complex suitable for X-ray diffraction analysis. The Journal of Biological Chemistry. 262: 4917-21. PMID 3549711 |
0.538 |
|
| 1987 |
Schevitz RW, Joachimiak A, Zhang R, Lawson CL, Marmorstein RQ, Otwinowski Z, Sigler PB. Thetrprepressor/operator system: the crystallography of ligand-activated genetic regulation Acta Crystallographica Section a Foundations of Crystallography. 43: C16-C16. DOI: 10.1107/S0108767387085118 |
0.674 |
|
| Show low-probability matches. |
