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Leonard I. Zon, M.D. - Publications

Affiliations: 
Chemical Biology Harvard University, Cambridge, MA, United States 
Area:
Genetics, Chemical Engineering, Human Development
Website:
https://hsci.harvard.edu/people/leonard-i-zon-md
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Year Citation  Score
2023 Bornhorst D, Gheller B, Zon LI. Colorimetric Barcoding to Track, Isolate, and Analyze Hematopoietic Stem Cell Clones. Methods in Molecular Biology (Clifton, N.J.). 2707: 265-277. PMID 37668919 DOI: 10.1007/978-1-0716-3401-1_18  0.322
2023 Binder V, Li W, Faisal M, Oyman K, Calkins DL, Shaffer J, Teets EM, Sher S, Magnotte A, Belardo A, Deruelle W, Gregory TC, Orwick S, Hagedorn EJ, Perlin JR, ... ... Zon LI, et al. Microenvironmental control of hematopoietic stem cell fate via CXCL8 and protein kinase C. Cell Reports. 42: 112528. PMID 37209097 DOI: 10.1016/j.celrep.2023.112528  0.31
2023 Hagedorn EJ, Perlin JR, Freeman RJ, Wattrus SJ, Han T, Mao C, Kim JW, Fernández-Maestre I, Daily ML, D'Amato C, Fairchild MJ, Riquelme R, Li B, Ragoonanan DAVE, Enkhbayar K, ... ... Zon LI, et al. Transcription factor induction of vascular blood stem cell niches in vivo. Developmental Cell. PMID 37119815 DOI: 10.1016/j.devcel.2023.04.007  0.338
2022 Sankaran VG, Weissman JS, Zon LI. Cellular barcoding to decipher clonal dynamics in disease. Science (New York, N.Y.). 378: eabm5874. PMID 36227997 DOI: 10.1126/science.abm5874  0.529
2022 Rubin SA, Baron CS, Pessoa Rodrigues C, Duran M, Corbin AF, Yang SP, Trapnell C, Zon LI. Single-cell analyses reveal early thymic progenitors and pre-B cells in zebrafish. The Journal of Experimental Medicine. 219. PMID 35938989 DOI: 10.1084/jem.20220038  0.33
2021 Fast EM, Sporrij A, Manning M, Rocha EL, Yang S, Zhou Y, Guo J, Baryawno N, Barkas N, Scadden D, Camargo F, Zon LI. External signals regulate continuous transcriptional states in hematopoietic stem cells. Elife. 10. PMID 34939923 DOI: 10.7554/eLife.66512  0.313
2021 He S, Zimmerman MW, Layden HM, Berezovskaya A, Etchin J, Martel MW, Thurston G, Jing CB, van Rooijen E, Kaufman CK, Rodig SJ, Zon LI, Patton EE, Mansour MR, Look AT. Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss. Oncogene. PMID 34331013 DOI: 10.1038/s41388-021-01926-y  0.669
2021 Avagyan S, Weber MC, Ma S, Prasad M, Mannherz WP, Yang S, Buenrostro JD, Zon LI. Single-cell ATAC-seq reveals GATA2-dependent priming defect in myeloid and a maturation bottleneck in lymphoid lineages. Blood Advances. 5: 2673-2686. PMID 34170284 DOI: 10.1182/bloodadvances.2020002992  0.337
2021 Patton EE, Mueller KL, Adams DJ, Anandasabapathy N, Aplin AE, Bertolotto C, Bosenberg M, Ceol CJ, Chi P, Herlyn M, Holmen SL, Karreth FA, Kaufman CK, Khan S, Kobold S, ... ... Zon LI, et al. Melanoma models for the next generation of therapies. Cancer Cell. PMID 33545064 DOI: 10.1016/j.ccell.2021.01.011  0.649
2021 Fazio M, van Rooijen E, Dang M, van de Hoek G, Ablain J, Mito JK, Yang S, Thomas A, Michael J, Fabo T, Modhurima R, Pessina P, Kaufman CK, Zhou Y, White RM, ... Zon LI, et al. SATB2 induction of a neural crest mesenchyme-like program drives melanoma invasion and drug resistance. Elife. 10. PMID 33527896 DOI: 10.7554/eLife.64370  0.684
2020 Taylor AM, Macari ER, Chan IT, Blair MC, Doulatov S, Vo LT, Raiser DM, Siva K, Basak A, Pirouz M, Shah AN, McGrath K, Humphries JM, Stillman E, Alter BP, ... ... Zon LI, et al. Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia. Science Translational Medicine. 12. PMID 33087503 DOI: 10.1126/scitranslmed.abb5831  0.582
2020 Hsu J, Huang HT, Lee CT, Choudhuri A, Wilson NK, Abraham BJ, Moignard V, Kucinski I, Yu S, Hyde RK, Tober J, Cai X, Li Y, Guo Y, Yang S, ... ... Zon LI, et al. CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation. Proceedings of the National Academy of Sciences of the United States of America. PMID 32883883 DOI: 10.1073/Pnas.2003228117  0.807
2020 Wattrus SJ, Zon LI. A Transgenic System for Rapid Magnetic Enrichment of Rare Embryonic Cells. Zebrafish. PMID 32749922 DOI: 10.1089/Zeb.2020.1904  0.414
2020 Minnoye L, Taskiran II, Mauduit D, Fazio M, Van Aerschot L, Hulselmans G, Christiaens V, Makhzami S, Seltenhammer M, Karras P, Primot A, Cadieu E, van Rooijen E, Marine JC, Egidy G, ... ... Zon L, et al. Cross-species analysis of enhancer logic using deep learning. Genome Research. PMID 32732264 DOI: 10.1101/Gr.260844.120  0.326
2020 Johansson JA, Marie KL, Lu Y, Brombin A, Santoriello C, Zeng Z, Zich J, Gautier P, von Kriegsheim A, Brunsdon H, Wheeler AP, Dreger M, Houston DR, Dooley CM, Sims AH, ... ... Zon LI, et al. PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation. Developmental Cell. PMID 32652076 DOI: 10.1016/J.Devcel.2020.06.013  0.402
2020 Choi J, Zhang T, Vu A, Ablain J, Makowski MM, Colli LM, Xu M, Hennessey RC, Yin J, Rothschild H, Gräwe C, Kovacs MA, Funderburk KM, Brossard M, Taylor J, ... ... Zon LI, et al. Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma. Nature Communications. 11: 2718. PMID 32483191 DOI: 10.1038/S41467-020-16590-1  0.355
2020 Miyata M, Gillemans N, Hockman D, Demmers JA, Cheng JF, Hou J, Salminen M, Fisher C, Taylor S, Gibbons RJ, Ganis JJ, Zon LI, Grosveld F, Mulugeta E, Sauka-Spengler T, et al. An evolutionary ancient mechanism for regulation of hemoglobin expression in vertebrate red cells. Blood. PMID 32396940 DOI: 10.1182/Blood.2020004826  0.382
2020 Makarova N, Kalaparthi V, Wang A, Williams C, Dokukin ME, Kaufman CK, Zon L, Sokolov I. Difference in biophysical properties of cancer-initiating cells in melanoma mutated zebrafish. Journal of the Mechanical Behavior of Biomedical Materials. 107: 103746. PMID 32364948 DOI: 10.1016/J.Jmbbm.2020.103746  0.707
2020 Chen MJ, Lummertz da Rocha E, Cahan P, Kubaczka C, Hunter P, Sousa P, Mullin NK, Fujiwara Y, Nguyen M, Tan Y, Landry S, Han A, Yang S, Lu YF, Jha DK, ... ... Zon LI, et al. Transcriptome Dynamics of Hematopoietic Stem Cell Formation Revealed Using a Combinatorial Runx1 and Ly6a Reporter System. Stem Cell Reports. PMID 32302558 DOI: 10.1016/J.Stemcr.2020.03.020  0.447
2020 Fazio M, Ablain J, Chuan Y, Langenau DM, Zon LI. Zebrafish patient avatars in cancer biology and precision cancer therapy. Nature Reviews. Cancer. 20: 263-273. PMID 32251397 DOI: 10.1038/S41568-020-0252-3  0.327
2020 Santoriello C, Sporrij A, Yang S, Flynn RA, Henriques T, Dorjsuren B, Custo Greig E, McCall W, Stanhope ME, Fazio M, Superdock M, Lichtig A, Adatto I, Abraham BJ, Kalocsay M, ... ... Zon LI, et al. RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells. Nature Cell Biology. PMID 32231306 DOI: 10.1038/S41556-020-0493-0  0.385
2020 Zhang B, Ma S, Rachmin I, He M, Baral P, Choi S, Gonçalves WA, Shwartz Y, Fast EM, Su Y, Zon LI, Regev A, Buenrostro JD, Cunha TM, Chiu IM, et al. Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells. Nature. PMID 31969699 DOI: 10.1038/S41586-020-1935-3  0.367
2020 Zhang B, Ma S, Rachman I, He M, Baral P, Choi S, Gonçalves W, Shwartz Y, Fast E, Su Y, Zon L, Regev A, Buenrostro J, Cunha T, Chiu I, et al. 775 Hyperactivation of sympathetic nerves drives melanocyte stem cell depletion Journal of Investigative Dermatology. 140: S102. DOI: 10.1016/J.Jid.2020.03.789  0.311
2019 Justice MJ, Hmeljak J, Sankaran VG, Socolovsky M, Zon LI. From blood development to disease: a paradigm for clinical translation. Disease Models & Mechanisms. PMID 31836582 DOI: 10.1242/Dmm.043661  0.528
2019 Jurynec MJ, Bai X, Bisgrove BW, Jackson H, Nechiporuk A, Palu RAS, Grunwald HA, Su YC, Hoshijima K, Yost HJ, Zon LI, Grunwald DJ. The Paf1 Complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors. Development (Cambridge, England). PMID 31784460 DOI: 10.1242/Dev.180133  0.457
2019 Li P, Lahvic JL, Binder V, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC, Zon LI. Author Correction: Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature. PMID 31435017 DOI: 10.1038/S41586-019-1489-4  0.771
2019 Tyrkalska SD, Pérez-Oliva AB, Rodríguez-Ruiz L, Martínez-Morcillo FJ, Alcaraz-Pérez F, Martínez-Navarro FJ, Lachaud C, Ahmed N, Schroeder T, Pardo-Sánchez I, Candel S, López-Muñoz A, Choudhuri A, Rossmann MP, Zon LI, et al. Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1. Immunity. PMID 31174991 DOI: 10.1016/J.Immuni.2019.05.005  0.412
2019 Gu Q, Yang X, Lv J, Zhang J, Xia B, Kim JD, Wang R, Xiong F, Meng S, Clements TP, Tandon B, Wagner DS, Diaz MF, Wenzel PL, Miller YI, ... ... Zon LI, et al. AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate. Science (New York, N.Y.). PMID 30705153 DOI: 10.1126/Science.Aav1749  0.416
2019 Zon L. Improving the visibility of developmental biology: time for induction and specification. Development (Cambridge, England). 146. PMID 30651297 DOI: 10.1242/Dev.174631  0.305
2019 Bowman TV, Zon LI. Lessons from the Niche for Generation and Expansion of Hematopoietic Stem Cells. Drug Discovery Today. Therapeutic Strategies. 6: 135-140. PMID 21212834 DOI: 10.1016/J.Ddstr.2009.06.003  0.402
2019 Thompson Z, Rodriguez M, Gabriel S, Anderson G, Binder V, Zon LI, Kathrein KL. Ing4 Regulates Stress Hematopoiesis and Represses Self-Renewal in Multipotent Progenitor Cells Blood. 134: 724-724. DOI: 10.1182/Blood-2019-129054  0.476
2019 Hagedorn EJ, Perlin JR, Freeman RJ, Mao C, Fernández-Maestre I, Daily ML, D'Amato CR, Wattrus SJ, Han T, Fairchild MJ, Riquelme R, Li B, Redfield SE, Collins SH, Lichtig A, ... ... Zon LI, et al. Transcription Factor Induction of Ectopic Vascular Blood Stem Cell Niches In Vivo Blood. 134: 525-525. DOI: 10.1182/Blood-2019-127219  0.455
2019 Rossmann MP, Hoi K, Chan V, Perlin JR, Hagedorn EJ, Abraham BJ, Yang S, Sullivan LB, Warren CR, Vyas S, Custo-Creig E, Dorjsuren B, Cowan C, Haigis MC, Young RA, ... Zon LI, et al. Transcriptional Regulation of Coenzyme Q Biosynthesis By TIF1γ Drives Erythropoiesis Blood. 134: 152-152. DOI: 10.1182/Blood-2019-126833  0.438
2019 Calkins DL, Shaffer JL, Teets EM, Belardo AM, Avagyan S, Zon LI, Blaser BW. Cxcl8 Expands Hematopoietic Stem and Progenitor Cells and Alters Their Interaction with the Endothelial Niche Blood. 134: 527-527. DOI: 10.1182/Blood-2019-126151  0.403
2018 Rost MS, Shestopalov I, Liu Y, Vo AH, Richter CE, Emly SM, Barrett FG, Stachura DL, Holinstat M, Zon LI, Shavit JA. Nfe2 is dispensable for early but required for adult thrombocyte formation and function in zebrafish. Blood Advances. 2: 3418-3427. PMID 30504234 DOI: 10.1182/Blood.V128.22.2534.2534  0.412
2018 Wattrus SJ, Zon LI. Stem cell safe harbor: the hematopoietic stem cell niche in zebrafish. Blood Advances. 2: 3063-3069. PMID 30425071 DOI: 10.1182/Bloodadvances.2018021725  0.422
2018 Ablain J, Xu M, Rothschild H, Jordan RC, Mito JK, Daniels BH, Bell CF, Joseph NM, Wu H, Bastian BC, Zon LI, Yeh I. Human tumor genomics and zebrafish modeling identify loss as a driver of mucosal melanoma. Science (New York, N.Y.). PMID 30385465 DOI: 10.1126/Science.Aau6509  0.376
2018 Yien YY, Shi J, Chen C, Cheung JT, Grillo AS, Shrestha R, Li L, Zhang X, Kafina MD, Kingsley PD, King MJ, Ablain J, Li H, Zon L, Palis J, et al. FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity. The Journal of Biological Chemistry. PMID 30366982 DOI: 10.1074/Jbc.Ra118.002742  0.465
2018 Parada-Kusz M, Penaranda C, Hagedorn EJ, Clatworthy A, Nair AV, Henninger JE, Ernst C, Li B, Riquelme R, Jijon H, Villablanca EJ, Zon LI, Hung D, Allende ML. Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies. Disease Models & Mechanisms. PMID 30266803 DOI: 10.1242/Dmm.034876  0.462
2018 Mandelbaum J, Shestopalov IA, Henderson RE, Chau NG, Knoechel B, Wick MJ, Zon LI. Zebrafish blastomere screen identifies retinoic acid suppression of in adenoid cystic carcinoma. The Journal of Experimental Medicine. PMID 30209067 DOI: 10.1084/Jem.20180939  0.386
2018 Lahvic JL, Ammerman M, Li P, Blair MC, Stillman ER, Fast EM, Robertson AL, Christodoulou C, Perlin JR, Yang S, Chiang N, Norris PC, Daily ML, Redfield SE, Chan IT, ... ... Zon LI, et al. Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132. Proceedings of the National Academy of Sciences of the United States of America. PMID 30139917 DOI: 10.1073/Pnas.1806077115  0.694
2018 Blaser BW, Zon LI. Making HSCs in vitro: don't forget the hemogenic endothelium. Blood. PMID 30089629 DOI: 10.1182/Blood-2018-04-784140  0.417
2018 Mansour MR, He S, Li Z, Lobbardi R, Abraham BJ, Hug C, Rahman S, Leon TE, Kuang YY, Zimmerman MW, Blonquist T, Gjini E, Gutierrez A, Tang Q, Garcia-Perez L, ... ... Zon LI, et al. JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia. The Journal of Experimental Medicine. PMID 29941549 DOI: 10.1084/Jem.20170484  0.312
2018 Kapp FG, Perlin JR, Hagedorn EJ, Gansner JM, Schwarz DE, O'Connell LA, Johnson NS, Amemiya C, Fisher DE, Wölfle U, Trompouki E, Niemeyer CM, Driever W, Zon LI. Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche. Nature. PMID 29899448 DOI: 10.1038/S41586-018-0213-0  0.323
2018 McConnell AM, Mito JK, Ablain J, Dang M, Formichella L, Fisher DE, Zon LI. Neural crest state activation in NRAS driven melanoma, but not in NRAS-driven melanocyte expansion. Developmental Biology. PMID 29883661 DOI: 10.1016/J.Ydbio.2018.05.026  0.36
2018 Uenishi GI, Jung HS, Kumar A, Park MA, Hadland BK, McLeod E, Raymond M, Moskvin O, Zimmerman CE, Theisen DJ, Swanson S, J Tamplin O, Zon LI, Thomson JA, Bernstein ID, et al. NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells. Nature Communications. 9: 1828. PMID 29739946 DOI: 10.1038/S41467-018-04134-7  0.399
2018 Bennett AH, O'Donohue MF, Gundry SR, Chan AT, Widrick J, Draper I, Chakraborty A, Zhou Y, Zon LI, Gleizes PE, Beggs AH, Gupta VA. RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes. Plos Genetics. 14: e1007226. PMID 29518074 DOI: 10.1371/Journal.Pgen.1007226  0.354
2018 Yu Y, Schleich K, Yue B, Ji S, Lohneis P, Kemper K, Silvis MS, Qutob N, van Rooijen E, Werner-Klein M, Li L, Dhawan D, Meierjohann S, Reimann M, Elkahloun A, ... ... Zon LI, et al. Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma. Cancer Cell. 33: 322-336.e8. PMID 29438700 DOI: 10.1016/J.Ccell.2018.01.002  0.361
2018 Yu SH, Zhu KY, Zhang F, Wang J, Yuan H, Chen Y, Jin Y, Dong M, Wang L, Jia XE, Gao L, Dong ZW, Ren CG, Chen LT, Huang QH, ... ... Zon LI, et al. The histone demethylase Jmjd3 regulates zebrafish myeloid development by promoting spi1 expression. Biochimica Et Biophysica Acta. PMID 29378332 DOI: 10.1016/J.Bbagrm.2017.12.009  0.428
2018 Blaser BW, Avagyan S, Zon L. Effect of enforced expression of cxcl8 by hematopoietic stem and progenitor cells on niche interactions and hematopoietic progenitor cells in adult zebrafish. Journal of Clinical Oncology. 36: 7070-7070. DOI: 10.1200/Jco.2018.36.15_Suppl.7070  0.433
2018 Yien YY, Shi J, Chen C, Cheung J, Grillo A, Shrestha R, Li L, Zhang X, Kafina MD, Kingsley PD, King M, Ablain J, Zon LI, Palis J, Burke M, et al. Target of Erythropoietin, Fam210b, Regulates Erythroid Heme Synthesis By Control of Mitochondrial Iron Import and Regulation of Fech Activity Blood. 132: 849-849. DOI: 10.1182/Blood-2018-99-120299  0.474
2018 Thompson Z, Binder V, Ammerman M, Durand E, Zon LI, Kathrein K. Ing4 Regulates Hematopoiesis through Suppression of NF-Kb Blood. 132: 642-642. DOI: 10.1182/Blood-2018-99-120033  0.52
2018 Choudhuri A, Trompouki E, Abraham BJ, Colli L, Mallard W, Yang M, Vinjamur D, Ghamari A, Nandakumar S, Hoi K, Hummel B, Boatman S, Chan V, Bowman TV, Yang S, ... ... Zon LI, et al. Transcriptional Signaling Centers Govern Human Erythropoiesis and Harbor Genetic Variations of Red Blood Cell Traits Blood. 132: 1277-1277. DOI: 10.1182/Blood-2018-99-118637  0.615
2018 Avagyan S, Mannherz WP, Zon LI. Early Clonal Hematopoiesis Detected in Gata2 heterozygosity By Color-Barcoding of Hematopoietic Stem Cells in Zebrafish Blood. 132: 748-748. DOI: 10.1182/Blood-2018-99-118236  0.426
2018 Sporrij A, Fast EM, Muhire B, Manning M, Kalocsay M, Kingston RE, Tolstorukov MY, Zon LI. Prostaglandin E2 Stimulates CREB-Mediated Modification of Histone Variant Nucleosomes at Enhancers to Promote Hematopoietic Stem Cell Fate Blood. 132: 530-530. DOI: 10.1182/Blood-2018-99-115232  0.397
2018 Scapin G, Cillis J, Patch T, Dharampuriya PR, Hagedorn EJ, Lundin V, Tamplin OJ, Andeson H, Zon LI, Daley GQ, Shah DI. Piezo1-Sensitive Biomechanical Pulsation Stimulates Long-Term Hematopoietic Stem Cell Formation Blood. 132: 3826-3826. DOI: 10.1182/Blood-2018-99-110265  0.751
2018 Ablain J, Dang M, Rothschild H, Zon LI. Abstract 93: Tissue-specific CRISPR in zebrafish identifies PVRL1 as a novel metastasis suppressor gene in melanoma Cancer Research. 78: 93-93. DOI: 10.1158/1538-7445.Am2018-93  0.435
2018 Fast E, Rodriguez-Fraticelli A, Sporrij A, Sun J, Durand E, Manning M, Hoi K, Ojeaburu L, Hayes T, Baryawno N, Guo J, Barkas N, Superdock M, Lichtig A, Yang S, ... ... Zon L, et al. A Short Pulse of Prostaglandin E2 (PGE2) Affects Long Term Clonal Dynamics during Hematopoietic Stem Cell Transplantation Experimental Hematology. 64: S46. DOI: 10.1016/J.Exphem.2018.06.056  0.308
2017 Kulkeaw K, Inoue T, Ishitani T, Nakanishi Y, Zon LI, Sugiyama D. Purification of zebrafish erythrocytes as a means of identifying a novel regulator of haematopoiesis. British Journal of Haematology. PMID 29265183 DOI: 10.1111/Bjh.15048  0.44
2017 Ben Nasr M, Tezza S, D'Addio F, Mameli C, Usuelli V, Maestroni A, Corradi D, Belletti S, Albarello L, Becchi G, Fadini GP, Schuetz C, Markmann J, Wasserfall C, Zon L, et al. PD-L1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor cells reverses autoimmune diabetes. Science Translational Medicine. 9. PMID 29141886 DOI: 10.1126/Scitranslmed.Aam7543  0.308
2017 Norris ML, Pauli A, Gagnon JA, Lord ND, Rogers KW, Mosimann C, Zon LI, Schier AF. Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling. Elife. 6. PMID 29117894 DOI: 10.7554/Elife.22626  0.36
2017 Crawford NG, Kelly DE, Hansen MEB, Beltrame MH, Fan S, Bowman SL, Jewett E, Ranciaro A, Thompson S, Lo Y, Pfeifer SP, Jensen JD, Campbell MC, Beggs W, Hormozdiari F, ... ... Zon L, et al. Loci associated with skin pigmentation identified in African populations. Science (New York, N.Y.). PMID 29025994 DOI: 10.1126/Science.Aan8433  0.306
2017 Neiswender JV, Kortum RL, Bourque C, Kasheta M, Zon L, Morrison DK, Ceol CJ. KIT suppresses BRAFV600E-mutant melanoma by attenuating oncogenic RAS/MAPK signaling. Cancer Research. PMID 28947418 DOI: 10.1158/0008-5472.Can-17-0473  0.336
2017 Ciarlo C, Kaufman CK, Kinikoglu B, Michael J, Yang S, D Amato C, Blokzijl-Franke S, den Hertog J, Schlaeger TM, Zhou Y, Liao E, Zon LI. A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development. Elife. 6. PMID 28832322 DOI: 10.7554/Elife.29145  0.725
2017 Perlin JR, Robertson AL, Zon LI. Efforts to enhance blood stem cell engraftment: Recent insights from zebrafish hematopoiesis. The Journal of Experimental Medicine. PMID 28830909 DOI: 10.1084/Jem.20171069  0.441
2017 McGonigle TA, Dwyer AR, Greenland EL, Scott NM, Keane KN, Newsholme P, Goodridge HS, Zon LI, Pixley FJ, Hart PH. PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo. Experimental Hematology. PMID 28822771 DOI: 10.1016/J.Exphem.2017.08.002  0.306
2017 Perlin JR, Sporrij A, Zon LI. Blood on the tracks: hematopoietic stem cell-endothelial cell interactions in homing and engraftment. Journal of Molecular Medicine (Berlin, Germany). PMID 28702683 DOI: 10.1007/S00109-017-1559-8  0.419
2017 Khajavi M, Zhou Y, Birsner AE, Bazinet L, Di Sant AR, Schiffer AJ, Rogers MS, Krishnaji ST, Hu B, Nguyen V, Zon L, D'Amato RJ. Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice. Plos Genetics. 13: e1006848. PMID 28617813 DOI: 10.1371/Journal.Pgen.1006848  0.379
2017 Choudhuri A, Fast EM, Zon LI. Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration. Stem Cell Reports. 8: 1465-1471. PMID 28591648 DOI: 10.1016/J.Stemcr.2017.05.018  0.411
2017 Fazio M, Avagyan S, van Rooijen E, Mannherz W, Kaufman CK, Lobbardi R, Langenau DM, Zon LI. Efficient Transduction of Zebrafish Melanoma Cell Lines and Embryos Using Lentiviral Vectors. Zebrafish. PMID 28557653 DOI: 10.1089/Zeb.2017.1434  0.715
2017 Hockman D, Burns A, Schlosser G, Gates KP, Jevans B, Mongera A, Fisher S, Unlu G, Knapik EW, Kaufman CK, Mosimann C, Zon LI, Lancman JJ, Dong PD, Lickert H, et al. Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes. Elife. 6. PMID 28387645 DOI: 10.7554/Elife.21231  0.724
2017 van Rooijen E, Fazio M, Zon LI. From fish bowl to bedside: The power of zebrafish to unravel melanoma pathogenesis and discover new therapeutics. Pigment Cell & Melanoma Research. PMID 28379616 DOI: 10.1111/Pcmr.12592  0.33
2017 Blaser BW, Moore JL, Hagedorn EJ, Li B, Riquelme R, Lichtig A, Yang S, Zhou Y, Tamplin OJ, Binder V, Zon LI. CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment. The Journal of Experimental Medicine. PMID 28351983 DOI: 10.1084/Jem.20161616  0.76
2017 Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee HY, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, ... ... Zon LI, et al. Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors. Science Translational Medicine. 9. PMID 28179501 DOI: 10.1126/Scitranslmed.Aah5645  0.454
2017 Volpi S, Yamazaki Y, Brauer PM, van Rooijen E, Hayashida A, Slavotinek A, Sun Kuehn H, Di Rocco M, Rivolta C, Bortolomai I, Du L, Felgentreff K, Ott de Bruin L, Hayashida K, Freedman G, ... ... Zon L, et al. EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay. The Journal of Experimental Medicine. PMID 28148688 DOI: 10.1084/Jem.20161525  0.41
2017 Henninger J, Santoso B, Hans S, Durand E, Moore J, Mosimann C, Brand M, Traver D, Zon L. Corrigendum: Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development. Nature Cell Biology. 19: 142. PMID 28139650 DOI: 10.1038/Ncb3462  0.366
2017 Gansner JM, Dang M, Ammerman M, Zon LI. Transplantation in zebrafish. Methods in Cell Biology. 138: 629-647. PMID 28129861 DOI: 10.1016/Bs.Mcb.2016.08.006  0.369
2017 Gansner JM, Leung AD, Superdock M, Blair MC, Ammerman MB, Durand EM, Barut B, Handin RI, Stachura DL, Lu C, Springer TA, Zon LI. Sorting zebrafish thrombocyte lineage cells with a Cd41 monoclonal antibody enriches hematopoietic stem cell activity. Blood. PMID 28126924 DOI: 10.1182/Blood-2016-12-759993  0.413
2017 Fast EM, Zon LI. Aging Hematopoietic Stem Cells Make Their History. Developmental Cell. 39: 390-391. PMID 27875682 DOI: 10.1016/J.Devcel.2016.11.005  0.352
2017 Ciarlo C, Kaufman CK, Kinikoglu B, Michael J, Yang S, D′Amato C, Blokzijl-Franke S, Hertog Jd, Schlaeger TM, Zhou Y, Liao E, Zon LI. Author response: A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development Elife. DOI: 10.7554/Elife.29145.064  0.724
2017 Hockman D, Burns AJ, Schlosser G, Gates KP, Jevans B, Mongera A, Fisher S, Unlu G, Knapik EW, Kaufman CK, Mosimann C, Zon LI, Lancman JJ, Dong PDS, Lickert H, et al. Author response: Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes Elife. DOI: 10.7554/Elife.21231.018  0.674
2017 Theodore L, Hagedorn E, Cortes M, Zon L, North T. Matrix metalloproteinases 2/9 are necessary for inflammatory-associated regulation of hematopoietic stem and progenitor cell production and function Experimental Hematology. 53: S63-S64. DOI: 10.1016/J.Exphem.2017.06.114  0.351
2016 Henninger J, Santoso B, Hans S, Durand E, Moore J, Mosimann C, Brand M, Traver D, Zon L. Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development. Nature Cell Biology. PMID 27870830 DOI: 10.1038/Ncb3444  0.425
2016 Rossmann MP, Zhou Y, Zon LI. Development: For cloche the Bell Tolls. Current Biology : Cb. 26: R890-R892. PMID 27728792 DOI: 10.1016/J.Cub.2016.08.009  0.389
2016 Robertson AL, Avagyan S, Gansner JM, Zon LI. Understanding the regulation of vertebrate hematopoiesis and blood disorders: big lessons from a small fish. Febs Letters. PMID 27616157 DOI: 10.1002/1873-3468.12415  0.409
2016 Aranda-Orgilles B, Saldaña-Meyer R, Wang E, Trompouki E, Fassl A, Lau S, Mullenders J, Rocha PP, Raviram R, Guillamot M, Sánchez-Díaz M, Wang K, Kayembe C, Zhang N, Amoasii L, ... ... Zon LI, et al. MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis. Cell Stem Cell. PMID 27570068 DOI: 10.1016/J.Stem.2016.08.004  0.422
2016 Nasrallah R, Fast EM, Solaimani P, Knezevic K, Eliades A, Patel R, Thambyrajah R, Unnikrishnan A, Thoms J, Beck D, Vink CS, Smith A, Wong J, Shepherd M, Kent D, ... ... Zon LI, et al. Identification of novel regulators of developmental hematopoiesis using endoglin regulatory elements as molecular probes. Blood. PMID 27554085 DOI: 10.1182/Blood-2016-02-697870  0.441
2016 Liu W, Wu M, Huang Z, Lian J, Chen J, Wang T, Leung AY, Liao Y, Zhang Z, Liu Q, Yen K, Lin S, Zon LI, Wen Z, Zhang Y, et al. c-myb hyperactivity leads to myeloid and lymphoid malignancies in zebrafish. Leukemia. PMID 27457538 DOI: 10.1038/Leu.2016.170  0.337
2016 Yang S, Ott CJ, Rossmann MP, Superdock M, Zon LI, Zhou Y. Chromatin immunoprecipitation and an open chromatin assay in zebrafish erythrocytes. Methods in Cell Biology. 135: 387-412. PMID 27443937 DOI: 10.1016/Bs.Mcb.2016.04.019  0.436
2016 Ablain J, Zon LI. Tissue-specific gene targeting using CRISPR/Cas9. Methods in Cell Biology. 135: 189-202. PMID 27443926 DOI: 10.1016/Bs.Mcb.2016.03.004  0.371
2016 Burberry A, Suzuki N, Wang JY, Moccia R, Mordes DA, Stewart MH, Suzuki-Uematsu S, Ghosh S, Singh A, Merkle FT, Koszka K, Li QZ, Zon L, Rossi DJ, Trowbridge JJ, et al. Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease. Science Translational Medicine. 8: 347ra93. PMID 27412785 DOI: 10.1126/Scitranslmed.Aaf6038  0.341
2016 Ray MK, Wiskow O, King MJ, Ismail N, Ergun A, Wang Y, Plys AJ, Davis CP, Kathrein K, Sadreyev R, Borowsky ML, Eggan K, Zon L, Galloway JL, Kingston RE. CAT7 and cat7l long non-coding RNAs Tune Polycomb Repressive Complex 1 Function During Human and Zebrafish Development. The Journal of Biological Chemistry. PMID 27405765 DOI: 10.1074/Jbc.M116.730853  0.717
2016 Hagedorn EJ, Cillis JL, Curley CR, Patch TC, Li B, Blaser BW, Riquelme R, Zon LI, Shah DI. Generation of Parabiotic Zebrafish Embryos by Surgical Fusion of Developing Blastulae. Journal of Visualized Experiments : Jove. PMID 27341538 DOI: 10.3791/54168  0.443
2016 Ciarlo CA, Zon LI. Embryonic cell culture in zebrafish. Methods in Cell Biology. 133: 1-10. PMID 27263406 DOI: 10.1016/Bs.Mcb.2016.02.010  0.341
2016 Rowe RG, Mandelbaum J, Zon LI, Daley GQ. Engineering Hematopoietic Stem Cells: Lessons from Development. Cell Stem Cell. 18: 707-20. PMID 27257760 DOI: 10.1016/J.Stem.2016.05.016  0.396
2016 Dang M, Fogley R, Zon LI. Identifying Novel Cancer Therapies Using Chemical Genetics and Zebrafish. Advances in Experimental Medicine and Biology. 916: 103-24. PMID 27165351 DOI: 10.1007/978-3-319-30654-4_5  0.346
2016 Svoboda O, Stachura DL, Machonova O, Zon LI, Traver D, Bartunek P. Ex vivo tools for the clonal analysis of zebrafish hematopoiesis. Nature Protocols. 11: 1007-20. PMID 27123951 DOI: 10.1038/Nprot.2016.053  0.444
2016 Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, ... ... Zon LI, et al. Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. Molecular Cell. 62: 34-46. PMID 27058786 DOI: 10.1016/J.Molcel.2016.03.013  0.377
2016 Wakabayashi A, Ulirsch JC, Ludwig LS, Fiorini C, Yasuda M, Choudhuri A, McDonel P, Zon LI, Sankaran VG. Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders. Proceedings of the National Academy of Sciences of the United States of America. PMID 27044088 DOI: 10.1073/Pnas.1521754113  0.592
2016 Avagyan S, Zon LI. FISH TO LEARN: INSIGHTS INTO BLOOD DEVELOPMENT AND BLOOD DISORDERS FROM ZEBRAFISH HEMATOPOIESIS. Human Gene Therapy. PMID 27018965 DOI: 10.1089/Hum.2016.024  0.339
2016 Gao X, Wu T, Johnson KD, Lahvic JL, Ranheim EA, Zon LI, Bresnick EH. GATA Factor-G-Protein-Coupled Receptor Circuit Suppresses Hematopoiesis. Stem Cell Reports. PMID 26905203 DOI: 10.1016/J.Stemcr.2016.01.008  0.438
2016 Kaufman CK, Mosimann C, Fan ZP, Yang S, Thomas AJ, Ablain J, Tan JL, Fogley RD, van Rooijen E, Hagedorn EJ, Ciarlo C, White RM, Matos DA, Puller AC, Santoriello C, ... ... Zon LI, et al. A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation. Science (New York, N.Y.). 351: aad2197. PMID 26823433 DOI: 10.1126/Science.Aad2197  0.727
2016 Huang J, Liu X, Li D, Shao Z, Cao H, Zhang Y, Trompouki E, Bowman TV, Zon LI, Yuan GC, Orkin SH, Xu J. Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis. Developmental Cell. 36: 9-23. PMID 26766440 DOI: 10.1016/J.Devcel.2015.12.014  0.528
2016 Norris ML, Pauli A, Gagnon JA, Lord ND, Rogers KW, Mosimann C, Zon LI, Schier AF. Author response: Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling Elife. DOI: 10.7554/Elife.22626.018  0.301
2016 Zon LI. Modeling Diamond Blackfan Anemia and p53 Activation in the Zebrafish Blood. 128: SCI-43-SCI-43. DOI: 10.1182/Blood.V128.22.Sci-43.Sci-43  0.448
2016 Lahvic JL, Ammerman MB, Li P, Yang S, Chiang N, Chase M, Weis O, Zhou Y, Serhan C, Zon LI. Eicosanoid-GPCR Signaling Enhances Hematopoiesis and Marrow Transplant Blood. 128: 495-495. DOI: 10.1182/Blood.V128.22.495.495  0.752
2016 Hagedorn EJ, Perlin JR, Mao C, Li B, D'Amato C, Riquelme R, Collins S, Holler K, van Oudenaarden A, Junker JP, Zon LI. Genome-Wide RNA Tomography of the Hematopoietic Stem Cell Niche in Zebrafish Reveals Unexpected Functional Macrophage-Stem Cell Interactions Blood. 128: 3882-3882. DOI: 10.1182/Blood.V128.22.3882.3882  0.445
2016 Macari ER, Taylor AM, Raiser D, Siva K, McGrath K, Humphries JM, Flygare J, Ebert BL, Zon LI. Calmodulin Inhibition Rescues DBA Models with Ribosomal Protein Deficiency through Reduction of RSK Signaling Blood. 128: 332-332. DOI: 10.1182/Blood.V128.22.332.332  0.38
2016 Avagyan S, Henninger JE, Moore J, Mannherz W, Zon LI. Modeling Clonal Hematopoietic Disorders in Zebrafish Using Color Barcoding Blood. 128: 3147-3147. DOI: 10.1182/Blood.V128.22.3147.3147  0.438
2016 Blaser BW, Moore JL, Hagedorn E, LI B, Binder V, Tamplin OJ, Zon LI. CXCR1 Mediates Dynamic Changes in the Vascular Niche and Promotes Hematopoietic Stem and Progenitor Cell Function Blood. 128: 172-172. DOI: 10.1182/Blood.V128.22.172.172  0.76
2016 Tamplin OJ, Henninger JE, Elliott HL, Richardson DS, Zon LI. A Zebrafish Model of Fetal Bone Marrow Provides a Dynamic View of Hematopoietic Stem Cell Niche Colonization Blood. 128: 170-170. DOI: 10.1182/Blood.V128.22.170.170  0.748
2016 Blaser BW, Moore JL, Hagedorn E, Li B, Binder V, Tamplin O, Zon LI. Abstract B035: CXCL8/CXCR1 signaling promotes angiogenesis and hematopoietic stem and progenitor cell function Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B035  0.762
2016 Kaufman CK, Mosimann C, Thomas A, Fan ZP, Yang S, Tan J, Fogley RD, Rooijen Ev, Hagedorn E, Ciarlo C, White R, Matos D, Puller A, Santoriello C, Liao E, ... ... Zon LI, et al. Abstract PR06: The reemergence of neural crest progenitor identity is a key event in the initiation of melanoma from a field of cancer-prone melanocytes Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-Pr06  0.738
2016 Aranda-Orgilles B, Saldaña-Meyer R, Wang E, Trompouki E, Schrewe H, Tsirigos A, Zon L, Aifantis I. Med12 is an essential regulator of enhancer dynamics in hematopoietic stem cells Experimental Hematology. 44: S57. DOI: 10.1016/J.Exphem.2016.06.086  0.388
2016 Doulatov S, Vo L, Macari E, Wahlster L, Taylor A, Gupta M, McGrath K, Narla A, Alter B, Gazda H, Sieff C, Agrawal S, Beggs A, Ebert B, Schlaeger T, ... Zon L, et al. Drug discovery using induced pluripotent stem cells identifies autophagy as a therapeutic pathway for anemia Experimental Hematology. 44: S48. DOI: 10.1016/J.Exphem.2016.06.063  0.361
2016 Zon LI. Pathways regulating stem cell induction, self-renewal and engraftment Experimental Hematology. 44: S37. DOI: 10.1016/J.Exphem.2016.06.036  0.37
2015 Musso G, Mosimann C, Panáková D, Burger A, Zhou Y, Zon LI, MacRae CA. Generating and evaluating a ranked candidate gene list for potential vertebrate heart field regulators. Genomics Data. 6: 199-201. PMID 26697374 DOI: 10.1016/J.Gdata.2015.09.015  0.341
2015 Giani FC, Fiorini C, Wakabayashi A, Ludwig LS, Salem RM, Jobaliya CD, Regan SN, Ulirsch JC, Liang G, Steinberg-Shemer O, Guo MH, Esko T, Tong W, Brugnara C, Hirschhorn JN, ... ... Zon LI, et al. Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells. Cell Stem Cell. PMID 26607381 DOI: 10.1016/J.Stem.2015.09.015  0.642
2015 Anderson H, Patch TC, Reddy PN, Hagedorn EJ, Kim PG, Soltis KA, Chen MJ, Tamplin OJ, Frye M, MacLean GA, Hübner K, Bauer DE, Kanki JP, Vogin G, Huston NC, ... ... Zon LI, et al. Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression. Blood. PMID 26385351 DOI: 10.1182/Blood-2015-07-659276  0.791
2015 Heilmann S, Ratnakumar K, Langdon E, Kansler E, Kim I, Campbell NR, Perry E, McMahon A, Kaufman C, van Rooijen E, Lee W, Iacobuzio-Donahue C, Hynes R, Zon L, Xavier J, et al. A quantitative system for studying metastasis using transparent zebrafish. Cancer Research. PMID 26282170 DOI: 10.1158/0008-5472.Can-14-3319  0.719
2015 Patsch C, Challet-Meylan L, Thoma EC, Urich E, Heckel T, O'Sullivan JF, Grainger SJ, Kapp FG, Sun L, Christensen K, Xia Y, Florido MH, He W, Pan W, Prummer M, ... ... Zon LI, et al. Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells. Nature Cell Biology. 17: 994-1003. PMID 26214132 DOI: 10.1038/Ncb3205  0.41
2015 Li P, Lahvic JL, Binder V, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC, Zon LI. Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature. 523: 468-71. PMID 26201599 DOI: 10.1038/Nature14569  0.819
2015 Jia XE, Ma K, Xu T, Gao L, Wu S, Fu C, Zhang W, Wang Z, Liu K, Dong M, Jing C, Ren C, Dong Z, Chen Y, Jin Y, ... ... Zon LI, et al. Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction. Cell Research. PMID 26138676 DOI: 10.1038/Cr.2015.81  0.398
2015 Gao L, Li D, Ma K, Zhang W, Xu T, Fu C, Jing C, Jia X, Wu S, Sun X, Dong M, Deng M, Chen Y, Zhu W, Peng J, ... ... Zon LI, et al. TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis. Plos Genetics. 11: e1005346. PMID 26131719 DOI: 10.1371/Journal.Pgen.1005346  0.385
2015 Liu X, Jia X, Yuan H, Ma K, Chen Y, Jin Y, Deng M, Pan W, Chen S, Chen Z, de The H, Zon LI, Zhou Y, Zhou J, Zhu J. DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish. Journal of Hematology & Oncology. 8: 15. PMID 25886310 DOI: 10.1186/S13045-015-0115-7  0.434
2015 Kim PG, Nakano H, Das PP, Chen MJ, Rowe RG, Chou SS, Ross SJ, Sakamoto KM, Zon LI, Schlaeger TM, Orkin SH, Nakano A, Daley GQ. Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence. The Journal of Experimental Medicine. 212: 633-48. PMID 25870201 DOI: 10.1084/Jem.20141514  0.529
2015 Jing L, Tamplin OJ, Chen MJ, Deng Q, Patterson S, Kim PG, Durand EM, McNeil A, Green JM, Matsuura S, Ablain J, Brandt MK, Schlaeger TM, Huttenlocher A, Daley GQ, ... ... Zon LI, et al. Adenosine signaling promotes hematopoietic stem and progenitor cell emergence. The Journal of Experimental Medicine. 212: 649-63. PMID 25870200 DOI: 10.1084/Jem.20141528  0.744
2015 Ablain J, Durand EM, Yang S, Zhou Y, Zon LI. A CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish. Developmental Cell. 32: 756-64. PMID 25752963 DOI: 10.1016/J.Devcel.2015.01.032  0.394
2015 Lin MI, Price EN, Boatman S, Hagedorn EJ, Trompouki E, Satishchandran S, Carspecken CW, Uong A, DiBiase A, Yang S, Canver MC, Dahlberg A, Lu Z, Zhang CC, Orkin SH, ... ... Zon LI, et al. Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling. Elife. 4. PMID 25714926 DOI: 10.7554/Elife.05544  0.568
2015 Tamplin OJ, Durand EM, Carr LA, Childs SJ, Hagedorn EJ, Li P, Yzaguirre AD, Speck NA, Zon LI. Hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche. Cell. 160: 241-52. PMID 25594182 DOI: 10.1016/J.Cell.2014.12.032  0.823
2015 Jang IH, Lu YF, Zhao L, Wenzel PL, Kume T, Datta SM, Arora N, Guiu J, Lagha M, Kim PG, Do EK, Kim JH, Schlaeger TM, Zon LI, Bigas A, et al. Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium. Blood. 125: 1418-26. PMID 25587036 DOI: 10.1182/Blood-2014-04-568170  0.431
2015 Gjini E, Mansour MR, Sander JD, Moritz N, Nguyen AT, Kesarsing M, Gans E, He S, Chen S, Ko M, Kuang YY, Yang S, Zhou Y, Rodig S, Zon LI, et al. A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing. Molecular and Cellular Biology. 35: 789-804. PMID 25512612 DOI: 10.1128/Mcb.00971-14  0.411
2015 Schlaeger TM, Daheron L, Brickler TR, Entwisle S, Chan K, Cianci A, DeVine A, Ettenger A, Fitzgerald K, Godfrey M, Gupta D, McPherson J, Malwadkar P, Gupta M, Bell B, ... ... Zon LI, et al. A comparison of non-integrating reprogramming methods. Nature Biotechnology. 33: 58-63. PMID 25437882 DOI: 10.1038/Nbt.3070  0.319
2015 Lin MI, Price EN, Boatman S, Hagedorn EJ, Trompouki E, Satishchandran S, Carspecken CW, Uong A, DiBiase A, Yang S, Canver MC, Dahlberg A, Lu Z, Zhang CC, Orkin SH, ... ... Zon LI, et al. Author response: Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling Elife. DOI: 10.7554/Elife.05544.021  0.426
2015 Blaser BW, Moore J, LI B, Tamplin OJ, Binder V, Zon LI. IL-8 and CXCR1 Remodel the Vascular Niche to Promote Hematopoietic Stem and Progenitor Cell Engraftment Blood. 126: 783-783. DOI: 10.1182/Blood.V126.23.783.783  0.753
2015 Macari ER, Taylor A, Raiser D, Siva K, McGrath K, Humphries JM, Flygare J, Ebert BL, Zon LI. Calmodulin Inhibition Rescues the Effects of Ribosomal Protein Deficiency in in Vitro and In Vivo Diamond Blackfan Anemia Models Blood. 126: 672-672. DOI: 10.1182/Blood.V126.23.672.672  0.402
2015 Yien YY, Chen C, Shi J, Li L, Bauer DE, Huston N, Kingsley PD, Ablain J, Zon LI, Palis J, Orkin SH, Kaplan J, Phillips JD, Lodish HF, Paw B. Fam210b Is Required for Optimal Cellular and Mitochondrial Iron Uptake during Erythroid Differentiation Blood. 126: 405-405. DOI: 10.1182/Blood.V126.23.405.405  0.5
2015 Boelig MM, Tsai J, Kim AG, Conner MA, Loukogeorgakis S, Li H, Li P, Zon LI, Flake AW, Peranteau WH. The Use of Eicosanoids to Enhance Donor Cell Engraftment after in Utero Hematopoietic Cell Transplantation (IUHCT) Blood. 126: 35-35. DOI: 10.1182/Blood.V126.23.35.35  0.72
2015 Fast EM, Durand EM, Sporrij A, Ojeaburu L, Maher R, Binder V, Yang S, Zhou Y, Zon LI. A Short Pulse of Prostaglandin E2 (PGE2) Induces Long Term Chromatin Changes in Hematopoietic Stem Cells Leading to Increased Self-Renewal and Engraftment Blood. 126: 246-246. DOI: 10.1182/Blood.V126.23.246.246  0.42
2015 Lin J, Yang C, Kwart A, Zhao J, Samur MK, Zhang W, Nanjappa P, Calimeri T, Ren X, Ma D, Jiang X, Zhou Y, Shammas M, Anderson KC, Aster JC, ... Zon LI, et al. Apurinic/Apyrimidinic Endonuclease 1 Induced Genomic Instability Causes T-Cell Acute Lymphoblastic Leukemia in Zebrafish Blood. 126: 1431-1431. DOI: 10.1182/Blood.V126.23.1431.1431  0.38
2015 Gao X, Wu T, Lahvic J, Johnson KD, Ranheim EA, Zon LI, Bresnick EH. A GATA-2-GPR65 Regulatory Module Controls Hematopoietic Stem Cell Generation Blood. 126: 1176-1176. DOI: 10.1182/Blood.V126.23.1176.1176  0.469
2014 Hagedorn EJ, Durand EM, Fast EM, Zon LI. Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2. Experimental Cell Research. 329: 220-6. PMID 25094063 DOI: 10.1016/J.Yexcr.2014.07.030  0.362
2014 Guo C, Chen X, Song H, Maynard MA, Zhou Y, Lobanov AV, Gladyshev VN, Ganis JJ, Wiley D, Jugo RH, Lee NY, Castroneves LA, Zon LI, Scanlan TS, Feldman HA, et al. Intrinsic expression of a multiexon type 3 deiodinase gene controls zebrafish embryo size. Endocrinology. 155: 4069-80. PMID 25004091 DOI: 10.1210/En.2013-2029  0.364
2014 Zon L, Cagan R. From fish tank to bedside in cancer therapy: an interview with Leonard Zon. Disease Models & Mechanisms. 7: 735-8. PMID 24973742 DOI: 10.1242/Dmm.016642  0.325
2014 Svoboda O, Stachura DL, Machoňová O, Pajer P, Brynda J, Zon LI, Traver D, Bartůněk P. Dissection of vertebrate hematopoiesis using zebrafish thrombopoietin. Blood. 124: 220-8. PMID 24869937 DOI: 10.1182/Blood-2014-03-564682  0.434
2014 Mirabello L, Macari ER, Jessop L, Ellis SR, Myers T, Giri N, Taylor AM, McGrath KE, Humphries JM, Ballew BJ, Yeager M, Boland JF, He J, Hicks BD, Burdett L, ... ... Zon L, et al. Whole-exome sequencing and functional studies identify RPS29 as a novel gene mutated in multicase Diamond-Blackfan anemia families. Blood. 124: 24-32. PMID 24829207 DOI: 10.1182/Blood-2013-11-540278  0.319
2014 Kong Y, Grimaldi M, Curtin E, Dougherty M, Kaufman C, White RM, Zon LI, Liao EC. Neural crest development and craniofacial morphogenesis is coordinated by nitric oxide and histone acetylation. Chemistry & Biology. 21: 488-501. PMID 24684905 DOI: 10.1016/J.Chembiol.2014.02.013  0.705
2014 Zhang X, Ling J, Barcia G, Jing L, Wu J, Barry BJ, Mochida GH, Hill RS, Weimer JM, Stein Q, Poduri A, Partlow JN, Ville D, Dulac O, Yu TW, ... ... Zon LI, et al. Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures. American Journal of Human Genetics. 94: 547-58. PMID 24656866 DOI: 10.1016/J.Ajhg.2014.03.003  0.327
2014 Hagedorn EJ, Zon LI. Unexpectedly uneven: posttransplant skeletal distribution of hematopoietic stem cell clones. The Journal of Experimental Medicine. 211: 384-5. PMID 24616474 DOI: 10.1084/Jem.2113Insight2  0.368
2014 Zhao C, Andreeva V, Gibert Y, LaBonty M, Lattanzi V, Prabhudesai S, Zhou Y, Zon L, McCann KL, Baserga S, Yelick PC. Tissue specific roles for the ribosome biogenesis factor Wdr43 in zebrafish development. Plos Genetics. 10: e1004074. PMID 24497835 DOI: 10.1371/Journal.Pgen.1004074  0.391
2014 Alcaraz-Pérez F, García-Castillo J, García-Moreno D, López-Muñoz A, Anchelin M, Angosto D, Zon LI, Mulero V, Cayuela ML. A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish. Nature Communications. 5: 3228. PMID 24496182 DOI: 10.1038/Ncomms4228  0.38
2014 Musso G, Tasan M, Mosimann C, Beaver JE, Plovie E, Carr LA, Chua HN, Dunham J, Zuberi K, Rodriguez H, Morris Q, Zon L, Roth FP, MacRae CA. Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish. Development (Cambridge, England). 141: 224-35. PMID 24346703 DOI: 10.1242/Dev.099796  0.371
2014 Tamplin OJ, Durand EM, Carr LA, Childs SJ, Hagedorn EH, Zon LI. High Resolution Imaging Reveals Hematopoietic Stem Cells in the Perivascular Niche Are Anchored to Mesenchymal Stromal Cells That Orient Their Divisions Blood. 124: 770-770. DOI: 10.1182/Blood.V124.21.770.770  0.755
2014 Rossmann MP, Bai X, Dorjsuren B, Krug L, Chiang C, Lee E, Chaudhry W, Kemet S, Adatto I, Zon LI. PPARα Activation Bypasses the Transcription Elongation Defect in Mutant tif1γ Erythroid Differentiation Blood. 124: 764-764. DOI: 10.1182/Blood.V124.21.764.764  0.461
2014 Blaser BW, Li B, Tamplin OJ, Binder V, Prober D, Schier A, Vidal M, Zon LI. Identification of Secreted Factors with a Role in Hematopoietic Stem and Progenitor Cell Engraftment in the Developing Zebrafish Blood. 124: 4361-4361. DOI: 10.1182/Blood.V124.21.4361.4361  0.775
2014 Doulatov S, Vo LT, Macari ER, Chou SS, Gupta M, Godfrey M, McGrath K, Schlaeger TM, Zon LI, Daley GQ. Modeling Diamond Blackfan Anemia in Vivo Using Human Induced Pluripotent Stem Cells Blood. 124: 359-359. DOI: 10.1182/Blood.V124.21.359.359  0.46
2014 Kaufman CK, Mosimann C, White R, Matos D, Zon LI. Abstract PR10: From melanocyte to melanoma: Identifying key molecular events at the onset of cancer Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-Pr10  0.74
2014 Zon LI. Abstract IA2: Developing therapeutics using the zebrafish Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-Ia2  0.426
2014 Kaufman CK, Mosimann C, White RM, Matos D, Zon LI. Abstract 2045: Identifying key molecular events at the onset of melanoma using a neural crest stem cell marker Cancer Research. 74: 2045-2045. DOI: 10.1158/1538-7445.Am2014-2045  0.751
2014 Choudhuri A, Abraham B, Mallard W, Hummel B, Boatman S, Bowman T, DiBiase A, Rinn J, Young R, Zon L, Trompouki E. Lineage regulators and signaling transcription factors during erythropoiesis Experimental Hematology. 42: S63. DOI: 10.1016/J.Exphem.2014.07.239  0.315
2014 Vo L, Doulatov S, Macari ER, Chou SS, Gupta M, Godfrey M, McGrath K, Schlaeger T, Zon LI, Daley G. Engineering hematopoietic stem and progenitor cells from human pluripotent stem cells for modeling congenital anemias Experimental Hematology. 42: S15. DOI: 10.1016/J.Exphem.2014.07.051  0.379
2013 Paik EJ, Mahony S, White RM, Price EN, Dibiase A, Dorjsuren B, Mosimann C, Davidson AJ, Gifford D, Zon LI. A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis. Stem Cell Reports. 1: 425-36. PMID 24286030 DOI: 10.1016/J.Stemcr.2013.10.001  0.81
2013 Huang HT, Kathrein KL, Barton A, Gitlin Z, Huang YH, Ward TP, Hofmann O, Dibiase A, Song A, Tyekucheva S, Hide W, Zhou Y, Zon LI. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nature Cell Biology. 15: 1516-25. PMID 24240475 DOI: 10.1182/Blood.V122.21.1174.1174  0.788
2013 Xu C, Tabebordbar M, Iovino S, Ciarlo C, Liu J, Castiglioni A, Price E, Liu M, Barton ER, Kahn CR, Wagers AJ, Zon LI. A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species. Cell. 155: 909-21. PMID 24209627 DOI: 10.1016/J.Cell.2013.10.023  0.351
2013 Chen CH, Durand E, Wang J, Zon LI, Poss KD. zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish. Development (Cambridge, England). 140: 4988-97. PMID 24198277 DOI: 10.1242/Dev.102053  0.375
2013 Yen J, White RM, Wedge DC, Van Loo P, de Ridder J, Capper A, Richardson J, Jones D, Raine K, Watson IR, Wu CJ, Cheng J, Martincorena I, Nik-Zainal S, Mudie L, ... ... Zon LI, et al. The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models. Genome Biology. 14: R113. PMID 24148783 DOI: 10.1186/Gb-2013-14-10-R113  0.682
2013 Stachura DL, Svoboda O, Campbell CA, Espín-Palazón R, Lau RP, Zon LI, Bartunek P, Traver D. The zebrafish granulocyte colony-stimulating factors (Gcsfs): 2 paralogous cytokines and their roles in hematopoietic development and maintenance. Blood. 122: 3918-28. PMID 24128862 DOI: 10.1182/Blood-2012-12-475392  0.398
2013 Doulatov S, Vo LT, Chou SS, Kim PG, Arora N, Li H, Hadland BK, Bernstein ID, Collins JJ, Zon LI, Daley GQ. Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell Stem Cell. 13: 459-70. PMID 24094326 DOI: 10.1016/J.Stem.2013.09.002  0.437
2013 Cutler C, Multani P, Robbins D, Kim HT, Le T, Hoggatt J, Pelus LM, Desponts C, Chen YB, Rezner B, Armand P, Koreth J, Glotzbecker B, Ho VT, Alyea E, ... ... Zon LI, et al. Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. Blood. 122: 3074-81. PMID 23996087 DOI: 10.1182/Blood-2013-05-503177  0.355
2013 Boatman S, Barrett F, Satishchandran S, Jing L, Shestopalov I, Zon LI. Assaying hematopoiesis using zebrafish. Blood Cells, Molecules & Diseases. 51: 271-6. PMID 23916372 DOI: 10.1016/J.Bcmd.2013.07.009  0.396
2013 Storer NY, White RM, Uong A, Price E, Nielsen GP, Langenau DM, Zon LI. Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis. Development (Cambridge, England). 140: 3040-50. PMID 23821038 DOI: 10.1242/Dev.087858  0.807
2013 Albacker CE, Storer NY, Langdon EM, Dibiase A, Zhou Y, Langenau DM, Zon LI. The histone methyltransferase SUV39H1 suppresses embryonal rhabdomyosarcoma formation in zebrafish. Plos One. 8: e64969. PMID 23705022 DOI: 10.1371/Journal.Pone.0064969  0.798
2013 Le X, Pugach EK, Hettmer S, Storer NY, Liu J, Wills AA, DiBiase A, Chen EY, Ignatius MS, Poss KD, Wagers AJ, Langenau DM, Zon LI. A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development. Development (Cambridge, England). 140: 2354-64. PMID 23615277 DOI: 10.1242/Dev.088427  0.799
2013 Howe K, Clark MD, Torroja CF, Torrance J, Berthelot C, Muffato M, Collins JE, Humphray S, McLaren K, Matthews L, McLaren S, Sealy I, Caccamo M, Churcher C, Scott C, ... ... Zon LI, et al. The zebrafish reference genome sequence and its relationship to the human genome. Nature. 496: 498-503. PMID 23594743 DOI: 10.1038/Nature12111  0.326
2013 Ciarlo CA, Zon LI. A model for primary melanoma of the CNS implicates NRAS. Cancer Discovery. 3: 382-3. PMID 23580282 DOI: 10.1158/2159-8290.Cd-13-0076  0.307
2013 Bowman TV, Zon LI. Ageing: Stem cells on a stress-busting diet. Nature. 494: 317-8. PMID 23389448 DOI: 10.1038/Nature11948  0.35
2013 Kim PG, Albacker CE, Lu YF, Jang IH, Lim Y, Heffner GC, Arora N, Bowman TV, Lin MI, Lensch MW, De Los Angeles A, Zon LI, Loewer S, Daley GQ. Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition. Proceedings of the National Academy of Sciences of the United States of America. 110: E141-50. PMID 23236128 DOI: 10.1073/Pnas.1214361110  0.412
2013 Jing CB, Chen Y, Dong M, Peng XL, Jia XE, Gao L, Ma K, Deng M, Liu TX, Zon LI, Zhu J, Zhou Y, Zhou Y. Phospholipase C gamma-1 is required for granulocyte maturation in zebrafish. Developmental Biology. 374: 24-31. PMID 23220656 DOI: 10.1016/J.Ydbio.2012.11.032  0.494
2013 Bai X, Trowbridge JJ, Riley E, Lee JA, DiBiase A, Kaartinen VM, Orkin SH, Zon LI. TiF1-gamma plays an essential role in murine hematopoiesis and regulates transcriptional elongation of erythroid genes. Developmental Biology. 373: 422-30. PMID 23159334 DOI: 10.1016/J.Ydbio.2012.10.008  0.559
2013 Cooney JD, Hildick-Smith GJ, Shafizadeh E, McBride PF, Carroll KJ, Anderson H, Shaw GC, Tamplin OJ, Branco DS, Dalton AJ, Shah DI, Wong C, Gallagher PG, Zon LI, North TE, et al. Teleost growth factor independence (gfi) genes differentially regulate successive waves of hematopoiesis. Developmental Biology. 373: 431-41. PMID 22960038 DOI: 10.1016/J.Ydbio.2012.08.015  0.75
2013 Zon LI. The Role of Chromatin Factors in Hematopoietic Development Blood. 122: SCI-48-SCI-48. DOI: 10.1182/Blood.V122.21.Sci-48.Sci-48  0.437
2013 Tamplin OJ, Durand EM, Carr LA, Li P, Zon LI. Hematopoietic Stem Cell Niche Interactions In The Embryo Can Modulate The Size Of The Stem Cell Pool Into Adulthood Blood. 122: 585-585. DOI: 10.1182/Blood.V122.21.585.585  0.76
2013 Lin MI, Price E, Boatman S, Trompouki E, Satishchandran S, Carspecken CW, Uong A, DiBiase A, Aster JC, White RM, Zon LI. Angiopoietin-Like Proteins Stimulate HSC Development Through Direct Interaction With Notch Blood. 122: 463-463. DOI: 10.1182/Blood.V122.21.463.463  0.403
2013 Mirabello L, Macari ER, Jessop L, Myers T, Giri N, Taylor AM, McGrath KE, Humphries JM, Ballew BJ, Yeager M, Boland JF, He J, Hicks BD, Burdett L, Alter BP, ... Zon LI, et al. Functional Consequences Of RPS29 Germline Mutations In Diamond-Blackfan Anemia Blood. 122: 2465-2465. DOI: 10.1182/Blood.V122.21.2465.2465  0.343
2013 Friedman AD, Guo H, Ma O, Zon LI, Shestopalov I, Kaufman DS, Ferrell PI. The RUNX1-Regulated Cebpa +37 Kb Enhancer Directs Human CD4 Transgene Expression To Long-Term Hematopoietic Stem Cells and Preferentially To Myeloid Compared With Lymphoid Or Erythroid Progenitors Blood. 122: 2442-2442. DOI: 10.1182/Blood.V122.21.2442.2442  0.425
2013 Hsu J, Huang H, Lee C, Yu S, Zon LI, Speck NA. Chromatin Remodeling Enzyme CHD7 Negatively Regulate Hematopoietic Stem Cell Function Blood. 122: 2413-2413. DOI: 10.1182/Blood.V122.21.2413.2413  0.808
2013 Binder V, Li P, Barrett F, Leung A, Zon LI. Diacylglycerol Enhances Hematopoietic Stem/Progenitor Cell Development and Engraftment Via MAP Kinase Activation Blood. 122: 174-174. DOI: 10.1182/Blood.V122.21.174.174  0.753
2013 Kathrein KL, Huang H, Barton A, Gitlin Z, Huang Y, Ward TP, Hofmann O, DiBiase A, Song A, Tyekucheva S, Hide W, Zhou Y, Zon LI. A Network Of Epigenetic Regulators Guide Developmental Hematopoiesis In Vivo Blood. 122: 1174-1174. DOI: 10.1182/blood.v122.21.1174.1174  0.797
2013 Zon LI. Abstract SY16-01: Transcriptional regulation and epigenetics in zebrafish cancer. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Sy16-01  0.369
2013 White RM, Langdon E, Kaufman C, Rooijen Ev, Yen J, Loo PV, Zon L. Abstract 3234: Comparative oncogenomics: identifying melanoma drivers from zebrafish to humans. Cancer Research. 73: 3234-3234. DOI: 10.1158/1538-7445.Am2013-3234  0.366
2013 Zon LI. Abstract CN03-03: Use of the zebrafish for studying cancer genetics. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-Cn03-03  0.374
2013 Bowman T, Cech J, Boatman S, Martin C, Sessa A, Leblanc J, Zhou Y, Zon L. Identification of quantitative genetic variations regulating hematopoietic regeneration Experimental Hematology. 41. DOI: 10.1016/J.Exphem.2013.05.148  0.317
2013 Zon L. Making and improving the function of adult blood stem cells Experimental Hematology. 41: S2. DOI: 10.1016/J.Exphem.2013.05.007  0.362
2013 Binder V, Zon LI. High throughput in vivo phenotyping: The zebrafish as tool for drug discovery for hematopoietic stem cells and cancer Drug Discovery Today: Disease Models. 10: e17-e22. DOI: 10.1016/J.Ddmod.2012.02.007  0.364
2012 Tamplin OJ, White RM, Jing L, Kaufman CK, Lacadie SA, Li P, Taylor AM, Zon LI. Small molecule screening in zebrafish: swimming in potential drug therapies. Wiley Interdisciplinary Reviews. Developmental Biology. 1: 459-68. PMID 23801494 DOI: 10.1002/Wdev.37  0.795
2012 McKinney-Freeman S, Cahan P, Li H, Lacadie SA, Huang HT, Curran M, Loewer S, Naveiras O, Kathrein KL, Konantz M, Langdon EM, Lengerke C, Zon LI, Collins JJ, Daley GQ. The transcriptional landscape of hematopoietic stem cell ontogeny. Cell Stem Cell. 11: 701-14. PMID 23122293 DOI: 10.1016/J.Stem.2012.07.018  0.811
2012 Mochida GH, Ganesh VS, de Michelena MI, Dias H, Atabay KD, Kathrein KL, Huang HT, Hill RS, Felie JM, Rakiec D, Gleason D, Hill AD, Malik AN, Barry BJ, Partlow JN, ... ... Zon LI, et al. CHMP1A encodes an essential regulator of BMI1-INK4A in cerebellar development. Nature Genetics. 44: 1260-4. PMID 23023333 DOI: 10.1038/Ng.2425  0.789
2012 Jing L, Durand EM, Ezzio C, Pagliuca SM, Zon LI. In situ hybridization assay-based small molecule screening in zebrafish. Current Protocols in Chemical Biology. 4. PMID 23001521 DOI: 10.1002/9780470559277.Ch110236  0.33
2012 Lian CG, Xu Y, Ceol C, Wu F, Larson A, Dresser K, Xu W, Tan L, Hu Y, Zhan Q, Lee CW, Hu D, Lian BQ, Kleffel S, Yang Y, ... ... Zon LI, et al. Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell. 150: 1135-46. PMID 22980977 DOI: 10.1016/J.Cell.2012.07.033  0.323
2012 Gupta VA, Kawahara G, Myers JA, Chen AT, Hall TE, Manzini MC, Currie PD, Zhou Y, Zon LI, Kunkel LM, Beggs AH. A splice site mutation in laminin-α2 results in a severe muscular dystrophy and growth abnormalities in zebrafish. Plos One. 7: e43794. PMID 22952766 DOI: 10.1371/Journal.Pone.0043794  0.32
2012 Sorrells S, Carbonneau S, Harrington E, Chen AT, Hast B, Milash B, Pyati U, Major MB, Zhou Y, Zon LI, Stewart RA, Look AT, Jette C. Ccdc94 protects cells from ionizing radiation by inhibiting the expression of p53. Plos Genetics. 8: e1002922. PMID 22952453 DOI: 10.1371/Journal.Pgen.1002922  0.356
2012 Oubaha M, Lin MI, Margaron Y, Filion D, Price EN, Zon LI, Côté JF, Gratton JP. Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1-induced collective directional migration and angiogenic sprouting. Blood. 120: 3371-81. PMID 22936663 DOI: 10.1182/Blood-2012-03-419721  0.35
2012 de Jong JL, Zon LI. Histocompatibility and hematopoietic transplantation in the zebrafish. Advances in Hematology. 2012: 282318. PMID 22778744 DOI: 10.1155/2012/282318  0.386
2012 Santoriello C, Zon LI. Hooked! Modeling human disease in zebrafish. The Journal of Clinical Investigation. 122: 2337-43. PMID 22751109 DOI: 10.1172/Jci60434  0.307
2012 Zon LI. A great match. Cell Stem Cell. 10: 638-9. PMID 22704496 DOI: 10.1016/J.Stem.2012.05.002  0.389
2012 Ganis JJ, Hsia N, Trompouki E, de Jong JL, DiBiase A, Lambert JS, Jia Z, Sabo PJ, Weaver M, Sandstrom R, Stamatoyannopoulos JA, Zhou Y, Zon LI. Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. Developmental Biology. 366: 185-94. PMID 22537494 DOI: 10.1016/J.Ydbio.2012.03.021  0.366
2012 Xu C, Fan ZP, Müller P, Fogley R, DiBiase A, Trompouki E, Unternaehrer J, Xiong F, Torregroza I, Evans T, Megason SG, Daley GQ, Schier AF, Young RA, Zon LI. Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. Developmental Cell. 22: 625-38. PMID 22421047 DOI: 10.1016/J.Devcel.2012.01.003  0.467
2012 Yu M, Mazor T, Huang H, Huang HT, Kathrein KL, Woo AJ, Chouinard CR, Labadorf A, Akie TE, Moran TB, Xie H, Zacharek S, Taniuchi I, Roeder RG, Kim CF, ... Zon LI, et al. Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. Molecular Cell. 45: 330-43. PMID 22325351 DOI: 10.1016/J.Molcel.2011.11.032  0.77
2012 Shestopalov IA, Zon LI. Stem cells: The right neighbour. Nature. 481: 453-5. PMID 22281591 DOI: 10.1038/481453A  0.45
2012 Bowman TV, Trompouki E, Zon LI. Linking hematopoietic regeneration to developmental signaling pathways: a story of BMP and Wnt. Cell Cycle (Georgetown, Tex.). 11: 424-5. PMID 22262185 DOI: 10.4161/Cc.11.3.19161  0.475
2012 Zhang L, Alt C, Li P, White RM, Zon LI, Wei X, Lin CP. An optical platform for cell tracking in adult zebrafish. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 176-82. PMID 22162445 DOI: 10.1002/Cyto.A.21167  0.714
2012 Taylor AM, Humphries JM, White RM, Murphey RD, Burns CE, Zon LI. Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation. Experimental Hematology. 40: 228-237.e5. PMID 22120640 DOI: 10.1016/J.Exphem.2011.11.007  0.829
2012 Hsu J, Huang H, Lee C, Yu S, Gerber S, Zon LI, Speck NA. CHD7 Negatively Regulates Hematopoietic Stem Cell Potency Blood. 120: 850-850. DOI: 10.1182/Blood.V120.21.850.850  0.803
2012 Ganis JJ, Riley EB, Palis J, Zon LI. A Screen for Regulators of Globin Switching in the Zebrafish Embryo Blood. 120: 826-826. DOI: 10.1182/Blood.V120.21.826.826  0.447
2012 Taylor AM, Raiser DM, Humphries JM, Ebert BL, Zon LI. Calmodulin Inhibition Rescues the Effects of Ribosomal Protein Deficiency by Modulating p53 Activity in Models of Diamond Blackfan Anemia Blood. 120: 512-512. DOI: 10.1182/Blood.V120.21.512.512  0.402
2012 Tamplin OJ, Durand E, Li P, Zon LI. Visualizing the Effects of Chemicals On Hematopoietic Stem Cell Engraftment in an Endogenous Niche Blood. 120: 506-506. DOI: 10.1182/Blood.V120.21.506.506  0.83
2012 Sykes DB, Haynes MK, Tolliday N, Waller A, Cobert JM, Szekely BA, Hasaka TP, Sklar L, Zon LI, Scadden DT. Identifying Small Molecules That Overcome HoxA9-Mediated Differentiation Arrest in Acute Myeloid Leukemia Blood. 120: 3513-3513. DOI: 10.1182/Blood.V120.21.3513.3513  0.446
2012 Zhang L, Alt C, Li P, White RM, Zon LI, Wei X, Lin CP. In vivo cell tracking and quantification method in adult zebrafish Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8225. DOI: 10.1117/12.909632  0.728
2012 Gupta V, Gundry S, Bass J, Chen A, Zhou Y, Zon L, Beggs A. G.P.3 Modeling congenital muscle diseases in zebrafish Neuromuscular Disorders. 22: 813. DOI: 10.1016/J.Nmd.2012.06.037  0.301
2011 Martin CS, Moriyama A, Zon LI. Hematopoietic stem cells, hematopoiesis and disease: lessons from the zebrafish model. Genome Medicine. 3: 83. PMID 22206610 DOI: 10.1186/Gm299  0.408
2011 Trompouki E, Bowman TV, Lawton LN, Fan ZP, Wu DC, DiBiase A, Martin CS, Cech JN, Sessa AK, Leblanc JL, Li P, Durand EM, Mosimann C, Heffner GC, Daley GQ, ... ... Zon LI, et al. Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration. Cell. 147: 577-89. PMID 22036566 DOI: 10.1182/Blood.V118.21.3387.3387  0.745
2011 Tan JL, Zon LI. Chemical screening in zebrafish for novel biological and therapeutic discovery. Methods in Cell Biology. 105: 493-516. PMID 21951544 DOI: 10.1016/Bs.Mcb.2016.10.004  0.306
2011 Li P, White RM, Zon LI. Transplantation in zebrafish. Methods in Cell Biology. 105: 403-17. PMID 21951540 DOI: 10.1016/B978-0-12-381320-6.00017-5  0.715
2011 Bugeon L, Taylor HB, Progatzky F, Lin MI, Ellis CD, Welsh N, Smith E, Vargesson N, Gray C, Renshaw SA, Chico TJ, Zon LI, Lamb J, Dallman MJ. The NOTCH pathway contributes to cell fate decision in myelopoiesis. Haematologica. 96: 1753-60. PMID 21933862 DOI: 10.3324/Haematol.2011.044115  0.413
2011 Trompouki E, Bowman TV, Dibiase A, Zhou Y, Zon LI. Chromatin immunoprecipitation in adult zebrafish red cells. Methods in Cell Biology. 104: 341-52. PMID 21924172 DOI: 10.1016/B978-0-12-374814-0.00019-7  0.37
2011 Mosimann C, Zon LI. Advanced zebrafish transgenesis with Tol2 and application for Cre/lox recombination experiments. Methods in Cell Biology. 104: 173-94. PMID 21924163 DOI: 10.1016/B978-0-12-374814-0.00010-0  0.325
2011 Bai X, Yang Z, Jiang H, Lin S, Zon LI. Genetic suppressor screens in haploids. Methods in Cell Biology. 104: 129-36. PMID 21924160 DOI: 10.1016/B978-0-12-374814-0.00007-0  0.371
2011 Adatto I, Lawrence C, Thompson M, Zon LI. A new system for the rapid collection of large numbers of developmentally staged zebrafish embryos. Plos One. 6: e21715. PMID 21738776 DOI: 10.1371/Journal.Pone.0021715  0.313
2011 Jing L, Zon LI. Zebrafish as a model for normal and malignant hematopoiesis. Disease Models & Mechanisms. 4: 433-8. PMID 21708900 DOI: 10.1242/Dmm.006791  0.353
2011 Glass TJ, Lund TC, Patrinostro X, Tolar J, Bowman TV, Zon LI, Blazar BR. Stromal cell-derived factor-1 and hematopoietic cell homing in an adult zebrafish model of hematopoietic cell transplantation. Blood. 118: 766-74. PMID 21622651 DOI: 10.1182/Blood-2011-01-328476  0.427
2011 Li P, Zon LI. Stem cell migration: a zebrafish model. Methods in Molecular Biology (Clifton, N.J.). 750: 157-68. PMID 21618090 DOI: 10.1007/978-1-61779-145-1_11  0.743
2011 Goessling W, Allen RS, Guan X, Jin P, Uchida N, Dovey M, Harris JM, Metzger ME, Bonifacino AC, Stroncek D, Stegner J, Armant M, Schlaeger T, Tisdale JF, Zon LI, et al. Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models. Cell Stem Cell. 8: 445-58. PMID 21474107 DOI: 10.1016/J.Stem.2011.02.003  0.794
2011 Taylor AM, Zon LI. Modeling Diamond Blackfan anemia in the zebrafish. Seminars in Hematology. 48: 81-8. PMID 21435504 DOI: 10.1053/J.Seminhematol.2011.02.002  0.36
2011 White RM, Cech J, Ratanasirintrawoot S, Lin CY, Rahl PB, Burke CJ, Langdon E, Tomlinson ML, Mosher J, Kaufman C, Chen F, Long HK, Kramer M, Datta S, Neuberg D, ... ... Zon LI, et al. DHODH modulates transcriptional elongation in the neural crest and melanoma. Nature. 471: 518-22. PMID 21430780 DOI: 10.1038/Nature09882  0.744
2011 Ceol CJ, Houvras Y, Jane-Valbuena J, Bilodeau S, Orlando DA, Battisti V, Fritsch L, Lin WM, Hollmann TJ, Ferré F, Bourque C, Burke CJ, Turner L, Uong A, Johnson LA, ... ... Zon LI, et al. The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature. 471: 513-7. PMID 21430779 DOI: 10.1038/Nature09806  0.357
2011 Stachura DL, Svoboda O, Lau RP, Balla KM, Zon LI, Bartunek P, Traver D. Clonal analysis of hematopoietic progenitor cells in the zebrafish. Blood. 118: 1274-82. PMID 21415264 DOI: 10.1182/Blood-2011-01-331199  0.445
2011 de Jong JL, Burns CE, Chen AT, Pugach E, Mayhall EA, Smith AC, Feldman HA, Zhou Y, Zon LI. Characterization of immune-matched hematopoietic transplantation in zebrafish. Blood. 117: 4234-42. PMID 21346254 DOI: 10.1182/Blood-2010-09-307488  0.362
2011 Bolli N, Payne EM, Rhodes J, Gjini E, Johnston AB, Guo F, Lee JS, Stewart RA, Kanki JP, Chen AT, Zhou Y, Zon LI, Look AT. cpsf1 is required for definitive HSC survival in zebrafish. Blood. 117: 3996-4007. PMID 21330472 DOI: 10.1182/Blood-2010-08-304030  0.462
2011 Lacadie SA, Zon LI. The ERGonomics of hematopoietic stem cell self-renewal. Genes & Development. 25: 289-93. PMID 21325129 DOI: 10.1101/Gad.2031511  0.376
2011 Gupta V, Kawahara G, Gundry SR, Chen AT, Lencer WI, Zhou Y, Zon LI, Kunkel LM, Beggs AH. The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies. Human Molecular Genetics. 20: 1712-25. PMID 21296866 DOI: 10.1093/Hmg/Ddr047  0.331
2011 Mosimann C, Kaufman CK, Li P, Pugach EK, Tamplin OJ, Zon LI. Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish. Development (Cambridge, England). 138: 169-77. PMID 21138979 DOI: 10.1242/Dev.059345  0.812
2011 Li P, Pugach EK, Riley EB, Panigrahy D, Heffner GC, Bowman TV, Tamplin OJ, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC, Zon LI. Epoxyeicosatrienoic Acids Regulate Hematopoietic Stem/Progenitor Cell Fate Decision During Stress Response and Embryonic Hematopoiesis Blood. 118: 860-860. DOI: 10.1182/Blood.V118.21.860.860  0.83
2011 Tamplin OJ, Durand EM, Lawson KL, Zon LI. Stem Cell Arrival in Sites of Hematopoiesis Triggers Supportive Endothelial Niche Formation Blood. 118: 218-218. DOI: 10.1182/Blood.V118.21.218.218  0.757
2011 Kim PG, Albacker CE, Jang I, Heffner GC, Lim Y, Bowman TV, Lin MI, Zon LI, Loewer S, Daley GQ. Scl and Notch Act Downstream of Hedgehog Signaling to Promote Embryonic Hematopoiesis From Endothelial Cells Blood. 118: 1283-1283. DOI: 10.1182/Blood.V118.21.1283.1283  0.438
2011 White RM, Zon LI. Abstract LB-335: DHODH regulates transcriptional elongation during melanoma evolution: insights from zebrafish screening Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-335  0.453
2011 Zon LI. Abstract PL02-01: Changing cell fate in cancer: Lessons from melanoma. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-Pl02-01  0.42
2010 Durand EM, Zon LI. Stem cells: The blood balance. Nature. 468: 644-5. PMID 21124447 DOI: 10.1038/468644A  0.383
2010 North TE, Babu IR, Vedder LM, Lord AM, Wishnok JS, Tannenbaum SR, Zon LI, Goessling W. PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury. Proceedings of the National Academy of Sciences of the United States of America. 107: 17315-20. PMID 20855591 DOI: 10.1073/Pnas.1008209107  0.317
2010 Paik EJ, Zon LI. Hematopoietic development in the zebrafish. The International Journal of Developmental Biology. 54: 1127-37. PMID 20711990 DOI: 10.1387/Ijdb.093042Ep  0.8
2010 Storer NY, Zon LI. Zebrafish models of p53 functions. Cold Spring Harbor Perspectives in Biology. 2: a001123. PMID 20679337 DOI: 10.1101/Cshperspect.A001123  0.798
2010 Tamplin OJ, Zon LI. Fishing at the cellular level. Nature Methods. 7: 600-1. PMID 20676080 DOI: 10.1038/Nmeth0810-600  0.712
2010 Tamplin OJ, Zon LI. Blood flow: metalloproteases cut loose in primitive erythrocytes. Current Biology : Cb. 20: R561-2. PMID 20619808 DOI: 10.1016/J.Cub.2010.05.014  0.695
2010 Bai X, Kim J, Yang Z, Jurynec MJ, Akie TE, Lee J, LeBlanc J, Sessa A, Jiang H, DiBiase A, Zhou Y, Grunwald DJ, Lin S, Cantor AB, Orkin SH, ... Zon LI, et al. TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell. 142: 133-43. PMID 20603019 DOI: 10.1016/J.Cell.2010.05.028  0.677
2010 Koo S, Huntly BJ, Wang Y, Chen J, Brumme K, Ball B, McKinney-Freeman SL, Yabuuchi A, Scholl C, Bansal D, Zon LI, Fröhling S, Daley GQ, Gilliland DG, Mercher T. Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis. Haematologica. 95: 1642-50. PMID 20494928 DOI: 10.3324/Haematol.2010.023168  0.438
2010 Durand EM, Zon LI. Newly emerging roles for prostaglandin E2 regulation of hematopoiesis and hematopoietic stem cell engraftment. Current Opinion in Hematology. 17: 308-12. PMID 20473159 DOI: 10.1097/Moh.0B013E32833A888C  0.392
2010 Paik EJ, de Jong JL, Pugach E, Opara P, Zon LI. A chemical genetic screen in zebrafish for pathways interacting with cdx4 in primitive hematopoiesis. Zebrafish. 7: 61-8. PMID 20415644 DOI: 10.1089/Zeb.2009.0643  0.811
2010 de Jong JL, Davidson AJ, Wang Y, Palis J, Opara P, Pugach E, Daley GQ, Zon LI. Interaction of retinoic acid and scl controls primitive blood development. Blood. 116: 201-9. PMID 20410509 DOI: 10.1182/Blood-2009-10-249557  0.379
2010 Wang Y, Krivtsov AV, Sinha AU, North TE, Goessling W, Feng Z, Zon LI, Armstrong SA. The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. Science (New York, N.Y.). 327: 1650-3. PMID 20339075 DOI: 10.1126/Science.1186624  0.344
2010 Trompouki E, Zon LI. Small molecule screen in zebrafish and HSC expansion. Methods in Molecular Biology (Clifton, N.J.). 636: 301-16. PMID 20336531 DOI: 10.1007/978-1-60761-691-7_19  0.418
2010 Li P, Zon LI. Resolving the controversy about N-cadherin and hematopoietic stem cells. Cell Stem Cell. 6: 199-202. PMID 20207222 DOI: 10.1016/J.Stem.2010.02.007  0.707
2010 Zon LI. Derivation of adult stem cells during embryogenesis. Harvey Lectures. 102: 117-32. PMID 20166566 DOI: 10.1002/9780470593042.Ch6  0.362
2010 Smith AC, Raimondi AR, Salthouse CD, Ignatius MS, Blackburn JS, Mizgirev IV, Storer NY, de Jong JL, Chen AT, Zhou Y, Revskoy S, Zon LI, Langenau DM. High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia. Blood. 115: 3296-303. PMID 20056790 DOI: 10.1182/Blood-2009-10-246488  0.799
2010 Chen AT, Zon LI. Zebrafish blood stem cells. Journal of Cellular Biochemistry. 108: 35-42. PMID 19565566 DOI: 10.1002/Jcb.22251  0.454
2010 Bai X, Trowbridge J, Lee J, Orkin SH, Zon LI. Analysis of TIF1gamma Conditional Knockout Establishes a Requirement for the Differentiation of Multiple Hematopoietic Lineages Blood. 116: 744-744. DOI: 10.1182/Blood.V116.21.744.744  0.583
2010 Lin MI, Carspecken CW, Uong A, Price E, Zon LI. Genetic Interaction Between Angiopoietin-Like Proteins 1 and 2 and Notch Signaling During HSC Development Blood. 116: 573-573. DOI: 10.1182/Blood.V116.21.573.573  0.402
2010 Trompouki E, Bowman TV, Lawton LN, Fan ZP, DiBiase A, Cech J, Sessa A, LeBlanc J, Li P, Heffner G, Daley GQ, Young R, Zon LI. BMP and WNT-Directed Transcription Factors TCF7L2/TCF4 and SMAD1 Bind to Distinct Hematopoietic-Specific Target Genes Depending on Cell Lineage Blood. 116: 3870-3870. DOI: 10.1182/Blood.V116.21.3870.3870  0.735
2010 Yu M, Mazor T, Huang H, Huang E, Kathrein K, Woo A, Zon LI, Fraenkel E, Cantor AB. Role of Polycomb Repressive Complex 1 (PRC1) In Runx1 Mediated Gene Regulation Blood. 116: 3863-3863. DOI: 10.1182/Blood.V116.21.3863.3863  0.409
2010 Bolli N, Payne E, Rhodes J, Johnston A, Guo F, Lee J, Kanki J, Chen AT, Zhou Y, Zon LI, Look AT. Cleavage and Polyadenylation Specificity Factor 1 Is Required for Definitive Hematopoietic Stem Cell Survival In Zebrafish. Blood. 116: 1606-1606. DOI: 10.1182/Blood.V116.21.1606.1606  0.509
2010 Huang H, Kathrein K, Huang Y, Gitlin Z, Barton A, Song A, Zhou Y, Zon LI. Chd7 Is a Cell Autonomous Regulator of Chromatin In Hematopoietic Stem Cells. Blood. 116: 1596-1596. DOI: 10.1182/Blood.V116.21.1596.1596  0.824
2010 Taylor AM, Humphries JM, White RM, Murphey RD, Burns CE, Zon LI. p53 Dependent and Dose Dependent Effects of Rps29 Mutation In the Zebrafish Embryo. Blood. 116: 1170-1170. DOI: 10.1182/Blood.V116.21.1170.1170  0.822
2009 Taylor AM, Zon LI. Zebrafish tumor assays: the state of transplantation. Zebrafish. 6: 339-46. PMID 20047467 DOI: 10.1089/Zeb.2009.0607  0.333
2009 Tournoij E, Weber GJ, Akkerman JW, de Groot PG, Zon LI, Moll FL, Schulte-Merker S. Mlck1a is expressed in zebrafish thrombocytes and is an essential component of thrombus formation. Journal of Thrombosis and Haemostasis : Jth. 8: 588-95. PMID 20002541 DOI: 10.1111/J.1538-7836.2009.03721.X  0.331
2009 Pugach EK, Li P, White R, Zon L. Retro-orbital injection in adult zebrafish. Journal of Visualized Experiments : Jove. PMID 19997061 DOI: 10.3791/1645  0.69
2009 Dovey M, White RM, Zon LI. Oncogenic NRAS cooperates with p53 loss to generate melanoma in zebrafish. Zebrafish. 6: 397-404. PMID 19954345 DOI: 10.1089/Zeb.2009.0606  0.797
2009 Uong A, Zon LI. Melanocytes in development and cancer. Journal of Cellular Physiology. 222: 38-41. PMID 19795394 DOI: 10.1002/Jcp.21935  0.368
2009 Kaufman CK, White RM, Zon L. Chemical genetic screening in the zebrafish embryo. Nature Protocols. 4: 1422-32. PMID 19745824 DOI: 10.1038/Nprot.2009.144  0.705
2009 Dovey MC, Zon LI. Defining cancer stem cells by xenotransplantation in zebrafish. Methods in Molecular Biology (Clifton, N.J.). 568: 1-5. PMID 19582417 DOI: 10.1007/978-1-59745-280-9_1  0.801
2009 North TE, Goessling W, Peeters M, Li P, Ceol C, Lord AM, Weber GJ, Harris J, Cutting CC, Huang P, Dzierzak E, Zon LI. Hematopoietic stem cell development is dependent on blood flow. Cell. 137: 736-48. PMID 19450519 DOI: 10.1016/J.Cell.2009.04.023  0.739
2009 Stachura DL, Reyes JR, Bartunek P, Paw BH, Zon LI, Traver D. Zebrafish kidney stromal cell lines support multilineage hematopoiesis. Blood. 114: 279-89. PMID 19433857 DOI: 10.1182/Blood-2009-02-203638  0.47
2009 Dovey M, Patton EE, Bowman T, North T, Goessling W, Zhou Y, Zon LI. Topoisomerase II alpha is required for embryonic development and liver regeneration in zebrafish. Molecular and Cellular Biology. 29: 3746-53. PMID 19380487 DOI: 10.1128/Mcb.01684-08  0.807
2009 Burns CE, Galloway JL, Smith AC, Keefe MD, Cashman TJ, Paik EJ, Mayhall EA, Amsterdam AH, Zon LI. A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence. Blood. 113: 5776-82. PMID 19332767 DOI: 10.1182/Blood-2008-12-193607  0.828
2009 Goessling W, North TE, Loewer S, Lord AM, Lee S, Stoick-Cooper CL, Weidinger G, Puder M, Daley GQ, Moon RT, Zon LI. Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell. 136: 1136-47. PMID 19303855 DOI: 10.1016/J.Cell.2009.01.015  0.417
2009 de Jong-Curtain TA, Parslow AC, Trotter AJ, Hall NE, Verkade H, Tabone T, Christie EL, Crowhurst MO, Layton JE, Shepherd IT, Nixon SJ, Parton RG, Zon LI, Stainier DY, Lieschke GJ, et al. Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish. Gastroenterology. 136: 902-11. PMID 19073184 DOI: 10.1053/J.Gastro.2008.11.012  0.411
2009 Fraenkel PG, Gibert Y, Holzheimer JL, Lattanzi VJ, Burnett SF, Dooley KA, Wingert RA, Zon LI. Transferrin-a modulates hepcidin expression in zebrafish embryos. Blood. 113: 2843-50. PMID 19047682 DOI: 10.1182/Blood-2008-06-165340  0.643
2009 Freeman JL, Ceol C, Feng H, Langenau DM, Belair C, Stern HM, Song A, Paw BH, Look AT, Zhou Y, Zon LI, Lee C. Construction and application of a zebrafish array comparative genomic hybridization platform. Genes, Chromosomes & Cancer. 48: 155-70. PMID 18973135 DOI: 10.1002/Gcc.20623  0.307
2009 Wang Y, Krivtsov AV, Sinha AU, North T, Goessling W, Zon LI, Armstrong S. β-Catenin Determines Developmental Stage Specific Transformation by Hox Genes. Blood. 114: 385-385. DOI: 10.1182/Blood.V114.22.385.385  0.352
2009 Goessling W, Guan X, Dovey M, Stegner J, Armant M, Schlaeger T, Zon LI, North T. Human Umbilical Cord Blood Stem Cell Function Is Augmented by Exposure to Prostaglandin E2. Blood. 114: 369-369. DOI: 10.1182/Blood.V114.22.369.369  0.802
2009 Lund T, Glass T, Tolar J, Zon LI, Blazar BR. A Model System for Visualization of Whole-Body Sdf-1 Expression During Hematopoietic Cell Transplant. Blood. 114: 3623-3623. DOI: 10.1182/Blood.V114.22.3623.3623  0.411
2009 de Jong J, Burns CE, Chen A, Pugach E, Mayhall E, Smith A, Feldman HA, Zhou Y, Zon LI. Long-Term Hematopoietic Transplantation in Zebrafish Using Immune-Matched Marrow Cells. Blood. 114: 3535-3535. DOI: 10.1182/Blood.V114.22.3535.3535  0.378
2009 Bai X, Lee J, LeBlanc J, Sessa A, Yang Z, Jiang H, Lin S, Zon LI. The Transcriptional Intermediary Factor TIF1γ Controls Erythroid Cell Fate by Specifically Regulating Transcriptional Elongation. Blood. 114: 254-254. DOI: 10.1182/Blood.V114.22.254.254  0.427
2009 Allen RS, Jin P, North T, Goessling W, Tian Y, Metzger ME, Bonifacino AC, Stroncek D, Zon LI, Donahue RE. Global Gene Expression Signatures in CD34+ Hematopoietic Cells Following Exposure to 16,16-Dimethylprostaglandin E2. Blood. 114: 2523-2523. DOI: 10.1182/Blood.V114.22.2523.2523  0.415
2009 Li P, Pugach E, Bowman TV, McKinney-Freeman S, Heffner G, Datta S, Daley GQ, Schlaeger T, Zon LI. Modulators of HSC Engraftment Found in A Competitive Marrow Transplantation Screen in Adult Zebrafish. Blood. 114: 2430-2430. DOI: 10.1182/Blood.V114.22.2430.2430  0.731
2008 Zon LI, Le X. Potential of zebrafish for anticancer drug screening. Expert Opinion On Drug Discovery. 3: 1451-60. PMID 23506108 DOI: 10.1517/17460440802580171  0.614
2008 Ceol CJ, Houvras Y, White RM, Zon LI. Melanoma biology and the promise of zebrafish. Zebrafish. 5: 247-55. PMID 19133823 DOI: 10.1089/Zeb.2008.0544  0.336
2008 Huang HT, Zon LI. Regulation of stem cells in the zebra fish hematopoietic system. Cold Spring Harbor Symposia On Quantitative Biology. 73: 111-8. PMID 19022765 DOI: 10.1101/Sqb.2008.73.029  0.798
2008 Imamura S, Uchiyama J, Koshimizu E, Hanai J, Raftopoulou C, Murphey RD, Bayliss PE, Imai Y, Burns CE, Masutomi K, Gagos S, Zon LI, Roberts TM, Kishi S. A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis. Plos One. 3: e3364. PMID 18846223 DOI: 10.1371/Journal.Pone.0003364  0.837
2008 Flores MV, Hall CJ, Davidson AJ, Singh PP, Mahagaonkar AA, Zon LI, Crosier KE, Crosier PS. Intestinal differentiation in zebrafish requires Cdx1b, a functional equivalent of mammalian Cdx2. Gastroenterology. 135: 1665-75. PMID 18804112 DOI: 10.1053/J.Gastro.2008.07.024  0.415
2008 Wang L, Sewell WF, Kim SD, Shin JT, MacRae CA, Zon LI, Seidman JG, Seidman CE. Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish. Development (Cambridge, England). 135: 3425-34. PMID 18799547 DOI: 10.1242/Dev.012237  0.398
2008 White RM, Zon LI. Melanocytes in development, regeneration, and cancer. Cell Stem Cell. 3: 242-52. PMID 18786412 DOI: 10.1016/J.Stem.2008.08.005  0.402
2008 Trede NS, Ota T, Kawasaki H, Paw BH, Katz T, Demarest B, Hutchinson S, Zhou Y, Hersey C, Zapata A, Amemiya CT, Zon LI. Zebrafish mutants with disrupted early T-cell and thymus development identified in early pressure screen. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 2575-84. PMID 18729230 DOI: 10.1002/Dvdy.21683  0.426
2008 Goessling W, North TE, Lord AM, Ceol C, Lee S, Weidinger G, Bourque C, Strijbosch R, Haramis AP, Puder M, Clevers H, Moon RT, Zon LI. APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development. Developmental Biology. 320: 161-74. PMID 18585699 DOI: 10.1016/J.Ydbio.2008.05.526  0.363
2008 Dooley KA, Fraenkel PG, Langer NB, Schmid B, Davidson AJ, Weber G, Chiang K, Foott H, Dwyer C, Wingert RA, Zhou Y, Paw BH, Zon LI. montalcino, A zebrafish model for variegate porphyria. Experimental Hematology. 36: 1132-42. PMID 18550261 DOI: 10.1016/J.Exphem.2008.04.008  0.665
2008 Zon LI. Self-Renewal and Differentiation at Cell Stem Cell Cell Stem Cell. 2: 510-510. PMID 18522838 DOI: 10.1016/J.Stem.2008.05.016  0.372
2008 Bussmann J, Lawson N, Zon L, Schulte-Merker S, Ekker M, Mullins M, Postlethwait J, Westerfield M. Zebrafish VEGF receptors: A guideline to nomenclature Plos Genetics. 4. PMID 18516225 DOI: 10.1371/Journal.Pgen.1000064  0.333
2008 Zon LI. Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal. Nature. 453: 306-13. PMID 18480811 DOI: 10.1038/Nature07038  0.355
2008 Zhu H, Zon LI. Use of zebrafish models for the analysis of human disease. Current Protocols in Human Genetics. Unit 15.3. PMID 18428328 DOI: 10.1002/0471142905.Hg1503S34  0.358
2008 White RM, Sessa A, Burke C, Bowman T, LeBlanc J, Ceol C, Bourque C, Dovey M, Goessling W, Burns CE, Zon LI. Transparent adult zebrafish as a tool for in vivo transplantation analysis. Cell Stem Cell. 2: 183-9. PMID 18371439 DOI: 10.1016/J.Stem.2007.11.002  0.803
2008 Lengerke C, Schmitt S, Bowman TV, Jang IH, Maouche-Chretien L, McKinney-Freeman S, Davidson AJ, Hammerschmidt M, Rentzsch F, Green JB, Zon LI, Daley GQ. BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway. Cell Stem Cell. 2: 72-82. PMID 18371423 DOI: 10.1016/J.Stem.2007.10.022  0.397
2008 Langenau DM, Keefe MD, Storer NY, Jette CA, Smith AC, Ceol CJ, Bourque C, Look AT, Zon LI. Co-injection strategies to modify radiation sensitivity and tumor initiation in transgenic Zebrafish. Oncogene. 27: 4242-8. PMID 18345029 DOI: 10.1038/Onc.2008.56  0.786
2008 Orkin SH, Zon LI. SnapShot: Hematopoiesis Cell. 132. PMID 18295585 DOI: 10.1016/j.cell.2008.02.013  0.422
2008 Orkin SH, Zon LI. Hematopoiesis: An Evolving Paradigm for Stem Cell Biology Cell. 132: 631-644. PMID 18295580 DOI: 10.1016/J.Cell.2008.01.025  0.565
2008 Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI. Combinatorial regulation of novel erythroid gene expression in zebrafish. Experimental Hematology. 36: 424-32. PMID 18243489 DOI: 10.1016/J.Exphem.2007.11.015  0.823
2008 Burket CT, Montgomery JE, Thummel R, Kassen SC, LaFave MC, Langenau DM, Zon LI, Hyde DR. Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters. Transgenic Research. 17: 265-79. PMID 17968670 DOI: 10.1007/S11248-007-9152-5  0.395
2008 Zon LI. Transcription Factor Integration from Pathways Regulating Adult Blood Stem Cell Production and Self-Renewal. Blood. 112: sci-14-sci-14. DOI: 10.1182/Blood.V112.11.Sci-14.Sci-14  0.378
2008 Lin MI, Zon LI. Genetic Analyses in Zebrafish Reveal That Angiopoietin-Like Proteins 1 and 2 Are Required for HSC Development during Embryogenesis Blood. 112: 729-729. DOI: 10.1182/Blood.V112.11.729.729  0.42
2008 North TE, Goessling W, Peeters M, Li P, Lord AM, Dzierzak E, Zon LI. Hematopoietic Stem Cell Development Is Dependent on Blood Flow and Nitric Oxide Signaling Blood. 112: 728-728. DOI: 10.1182/Blood.V112.11.728.728  0.734
2008 Li P, Zon LI. Direct Fluorescent Visualization of HSC Competitive Repopulation in Transparent Adult Zebrafish Blood. 112: 364-364. DOI: 10.1182/Blood.V112.11.364.364  0.663
2008 de Jong JLO, Burns CE, Tinmaung A, Pugach E, Mayhall E, Smith AC, Feldman HA, Zhou Y, Zon LI. Development of a Limiting Dilution Assay and MHC-Matched Transplantation Model to Detect Hematopoietic Stem Cell Activity in Zebrafish Blood. 112: 3489-3489. DOI: 10.1182/Blood.V112.11.3489.3489  0.39
2007 LeBlanc J, Bowman TV, Zon L. Transplantation of whole kidney marrow in adult zebrafish. Journal of Visualized Experiments : Jove. 159. PMID 18830422 DOI: 10.3791/159  0.405
2007 Lensch MW, Schlaeger TM, Zon LI, Daley GQ. Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera. Cell Stem Cell. 1: 253-8. PMID 18371359 DOI: 10.1016/J.Stem.2007.07.019  0.344
2007 Lord AM, North TE, Zon LI. Prostaglandin E2: making more of your marrow. Cell Cycle (Georgetown, Tex.). 6: 3054-7. PMID 18075310 DOI: 10.4161/Cc.6.24.5129  0.427
2007 Ceol CJ, Pellman D, Zon LI. APC and colon cancer: two hits for one. Nature Medicine. 13: 1286-7. PMID 17987022 DOI: 10.1038/Nm1107-1286  0.327
2007 Bahary N, Goishi K, Stuckenholz C, Weber G, Leblanc J, Schafer CA, Berman SS, Klagsbrun M, Zon LI. Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish. Blood. 110: 3627-36. PMID 17698971 DOI: 10.1182/Blood-2006-04-016378  0.351
2007 Steffen LS, Guyon JR, Vogel ED, Howell MH, Zhou Y, Weber GJ, Zon LI, Kunkel LM. The zebrafish runzel muscular dystrophy is linked to the titin gene. Developmental Biology. 309: 180-92. PMID 17678642 DOI: 10.1016/J.Ydbio.2007.06.015  0.355
2007 North TE, Goessling W, Walkley CR, Lengerke C, Kopani KR, Lord AM, Weber GJ, Bowman TV, Jang IH, Grosser T, Fitzgerald GA, Daley GQ, Orkin SH, Zon LI. Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature. 447: 1007-11. PMID 17581586 DOI: 10.1038/Nature05883  0.576
2007 Paffett-Lugassy N, Hsia N, Fraenkel PG, Paw B, Leshinsky I, Barut B, Bahary N, Caro J, Handin R, Zon LI. Functional conservation of erythropoietin signaling in zebrafish Blood. 110: 2718-2726. PMID 17579187 DOI: 10.1182/Blood-2006-04-016535  0.824
2007 Pfaff KL, Straub CT, Chiang K, Bear DM, Zhou Y, Zon LI. The zebra fish cassiopeia mutant reveals that SIL is required for mitotic spindle organization. Molecular and Cellular Biology. 27: 5887-97. PMID 17576815 DOI: 10.1128/Mcb.00175-07  0.744
2007 Le X, Langenau DM, Keefe MD, Kutok JL, Neuberg DS, Zon LI. Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 104: 9410-5. PMID 17517602 DOI: 10.1073/Pnas.0611302104  0.636
2007 Langenau DM, Keefe MD, Storer NY, Guyon JR, Kutok JL, Le X, Goessling W, Neuberg DS, Kunkel LM, Zon LI. Effects of RAS on the genesis of embryonal rhabdomyosarcoma. Genes & Development. 21: 1382-95. PMID 17510286 DOI: 10.1101/Gad.1545007  0.811
2007 Trede NS, Medenbach J, Damianov A, Hung LH, Weber GJ, Paw BH, Zhou Y, Hersey C, Zapata A, Keefe M, Barut BA, Stuart AB, Katz T, Amemiya CT, Zon LI, et al. Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110. Proceedings of the National Academy of Sciences of the United States of America. 104: 6608-13. PMID 17416673 DOI: 10.1073/Pnas.0701919104  0.341
2007 Steffen LS, Guyon JR, Vogel ED, Beltre R, Pusack TJ, Zhou Y, Zon LI, Kunkel LM. Zebrafish orthologs of human muscular dystrophy genes. Bmc Genomics. 8: 79. PMID 17374169 DOI: 10.1186/1471-2164-8-79  0.342
2007 Peng CY, Yajima H, Burns CE, Zon LI, Sisodia SS, Pfaff SL, Sharma K. Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord. Neuron. 53: 813-27. PMID 17359917 DOI: 10.1016/J.Neuron.2007.02.019  0.374
2007 Hultman KA, Bahary N, Zon LI, Johnson SL. Gene Duplication of the zebrafish kit ligand and partitioning of melanocyte development functions to kit ligand a. Plos Genetics. 3: e17. PMID 17257055 DOI: 10.1371/Journal.Pgen.0030017  0.341
2007 Shepard JL, Amatruda JF, Finkelstein D, Ziai J, Finley KR, Stern HM, Chiang K, Hersey C, Barut B, Freeman JL, Lee C, Glickman JN, Kutok JL, Aster JC, Zon LI. A mutation in separase causes genome instability and increased susceptibility to epithelial cancer. Genes & Development. 21: 55-9. PMID 17210788 DOI: 10.1101/Gad.1470407  0.761
2007 Fraenkel PG, Burnett S, Holzheimer J, Dooley KA, Wingert R, Hammerschmidt M, Zon LI. Transferrin Acts as an Iron Sensor Upstream of BMP2b in the Zebrafish. Blood. 110: 704-704. DOI: 10.1182/Blood.V110.11.704.704  0.621
2007 Jong JLd, Davidson AJ, Wang Y, Palis J, Daley GQ, Zon LI. Retinoic Acid Blockade Increases Primitive Blood Cell Formation in cdx4 Mutant Zebrafish Embryos, Murine Yolk Sac Explants and Differentiated Embryonic Stem Cells. Blood. 110: 201-201. DOI: 10.1182/Blood.V110.11.201.201  0.453
2007 Lengerke C, Schmitt S, Bowman T, Maouche-Chretien L, McKinney-Freeman SL, Jang IH, Davidson AJ, Hammerschmidt M, Rentzsch F, Green JB, Zon LI, Daley GQ. BMP and Wnt Induce Embryonic Blood Fate by Activation of the Cdx-Hox Pathway. Blood. 110: 199-199. DOI: 10.1182/Blood.V110.11.199.199  0.454
2007 North TE, Goessling W, Armant M, Kao GS, Silberstein LE, Ritz J, Zon LI. Ex Vivo Treatment of Human Cord Blood with dmPGE2 Can Safely Increase the Potential for Hematopoietic Engraftment. Blood. 110: 1190-1190. DOI: 10.1182/Blood.V110.11.1190.1190  0.413
2007 Zon LI. The International Society for Stem Cell Research: a paradigm for international collaboration Stem Cells. 1-1. DOI: 10.1038/Stemcells.2007.53  0.32
2007 North TE, Goessling W, Kopani KR, Mayhall E, Jang I, Lengerke C, Burns CE, Lord A, Grosser T, FitzGerald GA, Daley GQ, Zon LI. A high-throughput chemical genetic screen in zebrafish establishes that prostaglandin E2 is a potent regulator of hematopoietic stem cell formation Blood Cells, Molecules, and Diseases. 38: 191. DOI: 10.1016/J.Bcmd.2006.10.159  0.408
2007 Hsia N, Axe JL, Paffett-Lugassy N, Zhou Y, Zon LI. Globin switching in the zebrafish Blood Cells, Molecules, and Diseases. 38: 145. DOI: 10.1016/J.Bcmd.2006.10.062  0.764
2006 Burns CE, Zon LI. Homing sweet homing: odyssey of hematopoietic stem cells. Immunity. 25: 859-62. PMID 17174927 DOI: 10.1016/J.Immuni.2006.11.006  0.388
2006 Murphey RD, Stern HM, Straub CT, Zon LI. A chemical genetic screen for cell cycle inhibitors in zebrafish embryos. Chemical Biology & Drug Design. 68: 213-9. PMID 17105485 DOI: 10.1111/J.1747-0285.2006.00439.X  0.801
2006 Bansal D, Scholl C, Fröhling S, McDowell E, Lee BH, Döhner K, Ernst P, Davidson AJ, Daley GQ, Zon LI, Gilliland DG, Huntly BJ. Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model. Proceedings of the National Academy of Sciences of the United States of America. 103: 16924-9. PMID 17068127 DOI: 10.1182/Blood.V108.11.10.10  0.399
2006 Hu G, Tang J, Zhang B, Lin Y, Hanai J, Galloway J, Bedell V, Bahary N, Han Z, Ramchandran R, Thisse B, Thisse C, Zon LI, Sukhatme VP. A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro. Journal of Cell Science. 119: 4117-26. PMID 16968741 DOI: 10.1242/Jcs.03179  0.726
2006 Murphey RD, Zon LI. Small molecule screening in the zebrafish. Methods (San Diego, Calif.). 39: 255-61. PMID 16877005 DOI: 10.1016/J.Ymeth.2005.09.019  0.794
2006 Goishi K, Shimizu A, Najarro G, Watanabe S, Rogers R, Zon LI, Klagsbrun M. AlphaA-crystallin expression prevents gamma-crystallin insolubility and cataract formation in the zebrafish cloche mutant lens. Development (Cambridge, England). 133: 2585-93. PMID 16728471 DOI: 10.1242/Dev.02424  0.358
2006 Gupta S, Zhu H, Zon LI, Evans T. BMP signaling restricts hemato-vascular development from lateral mesoderm during somitogenesis. Development (Cambridge, England). 133: 2177-87. PMID 16672337 DOI: 10.1242/Dev.02386  0.396
2006 Shaw GC, Cope JJ, Li L, Corson K, Hersey C, Ackermann GE, Gwynn B, Lambert AJ, Wingert RA, Traver D, Trede NS, Barut BA, Zhou Y, Minet E, Donovan A, ... ... Zon LI, et al. Mitoferrin is essential for erythroid iron assimilation. Nature. 440: 96-100. PMID 16511496 DOI: 10.1038/Nature04512  0.788
2006 Davidson AJ, Zon LI. The caudal-related homeobox genes cdx1a and cdx4 act redundantly to regulate hox gene expression and the formation of putative hematopoietic stem cells during zebrafish embryogenesis. Developmental Biology. 292: 506-18. PMID 16457800 DOI: 10.1016/J.Ydbio.2006.01.003  0.498
2006 Protas ME, Hersey C, Kochanek D, Zhou Y, Wilkens H, Jeffery WR, Zon LI, Borowsky R, Tabin CJ. Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism. Nature Genetics. 38: 107-11. PMID 16341223 DOI: 10.1038/Ng1700  0.308
2006 Tang J, Hu G, Hanai J, Yadlapalli G, Lin Y, Zhang B, Galloway J, Bahary N, Sinha S, Thisse B, Thisse C, Jin JP, Zon LI, Sukhatme VP. A critical role for calponin 2 in vascular development. The Journal of Biological Chemistry. 281: 6664-72. PMID 16317011 DOI: 10.1074/Jbc.M506991200  0.731
2006 de Jong JL, Zon LI. Use of the zebrafish system to study primitive and definitive hematopoiesis. Annual Review of Genetics. 39: 481-501. PMID 16285869 DOI: 10.1146/Annurev.Genet.39.073003.095931  0.429
2006 MacDonald BA, Sund M, Grant MA, Pfaff KL, Holthaus K, Zon LI, Kalluri R. Zebrafish to humans: evolution of the alpha3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome. Blood. 107: 1908-15. PMID 16254142 DOI: 10.1182/Blood-2005-05-1814  0.682
2006 Gardiner MR, Daggett DF, Zon LI, Perkins AC. Zebrafish KLF4 is essential for anterior mesendoderm/pre-polster differentiation and hatching. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 234: 992-6. PMID 16222715 DOI: 10.1002/Dvdy.20571  0.457
2006 North TE, Goessling W, Kopani KR, Lengerke C, Walkley CR, Lord AM, Jang I, Grosser T, FitzGerald GA, Daley GQ, Orkin SH, Zon LI. Prostaglandin E2 Is a Potent Regulator of Vertebrate Hematopoietic Stem Cell Homeostasis. Blood. 108: 680-680. DOI: 10.1182/Blood.V108.11.680.680  0.592
2006 Le X, Langenau DM, Keefe MD, Kutok JL, Zon LI. Inducible hkRASG12D Expression in Zebrafish Hematopoietic Cells Leads to Myeloproliferative Disease. Blood. 108: 2691-2691. DOI: 10.1182/Blood.V108.11.2691.2691  0.423
2006 Fraenkel PG, Dooley KA, Zon LI. Requirement of Transferrin for Iron-Induced Hepcidin Expression in the Zebrafish. Blood. 108: 1538-1538. DOI: 10.1182/Blood.V108.11.1538.1538  0.351
2005 Patton EE, Zon LI. Taking human cancer genes to the fish: a transgenic model of melanoma in zebrafish. Zebrafish. 1: 363-8. PMID 18248215 DOI: 10.1089/Zeb.2005.1.363  0.312
2005 Stern HM, Murphey RD, Shepard JL, Amatruda JF, Straub CT, Pfaff KL, Weber G, Tallarico JA, King RW, Zon LI. Small molecules that delay S phase suppress a zebrafish bmyb mutant. Nature Chemical Biology. 1: 366-70. PMID 16372403 DOI: 10.1038/Nchembio749  0.81
2005 Burns CE, Traver D, Mayhall E, Shepard JL, Zon LI. Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes & Development. 19: 2331-42. PMID 16166372 DOI: 10.1101/Gad.1337005  0.806
2005 Shepard JL, Amatruda JF, Stern HM, Subramanian A, Finkelstein D, Ziai J, Finley KR, Pfaff KL, Hersey C, Zhou Y, Barut B, Freedman M, Lee C, Spitsbergen J, Neuberg D, ... ... Zon LI, et al. A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Proceedings of the National Academy of Sciences of the United States of America. 102: 13194-9. PMID 16150706 DOI: 10.1073/Pnas.0506583102  0.815
2005 Hsia N, Zon LI. Transcriptional regulation of hematopoietic stem cell development in zebrafish. Experimental Hematology. 33: 1007-14. PMID 16140148 DOI: 10.1016/J.Exphem.2005.06.013  0.45
2005 Wingert RA, Galloway JL, Barut B, Foott H, Fraenkel P, Axe JL, Weber GJ, Dooley K, Davidson AJ, Schmid B, Schmidt B, Paw BH, Shaw GC, Kingsley P, Palis J, ... ... Zon LI, et al. Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis. Nature. 436: 1035-39. PMID 16110529 DOI: 10.1038/Nature03887  0.77
2005 Lin HF, Traver D, Zhu H, Dooley K, Paw BH, Zon LI, Handin RI. Analysis of thrombocyte development in CD41-GFP transgenic zebrafish. Blood. 106: 3803-10. PMID 16099879 DOI: 10.1182/Blood-2005-01-0179  0.407
2005 Donovan A, Lima CA, Pinkus JL, Pinkus GS, Zon LI, Robine S, Andrews NC. The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metabolism. 1: 191-200. PMID 16054062 DOI: 10.1016/J.Cmet.2005.01.003  0.74
2005 Shmukler BE, Kurschat CE, Ackermann GE, Jiang L, Zhou Y, Barut B, Stuart-Tilley AK, Zhao J, Zon LI, Drummond IA, Vandorpe DH, Paw BH, Alper SL. Zebrafish slc4a2/ae2 anion exchanger: cDNA cloning, mapping, functional characterization, and localization. American Journal of Physiology. Renal Physiology. 289: F835-49. PMID 15914778 DOI: 10.1152/Ajprenal.00122.2005  0.353
2005 Fraenkel PG, Traver D, Donovan A, Zahrieh D, Zon LI. Ferroportin1 is required for normal iron cycling in zebrafish Journal of Clinical Investigation. 115: 1532-1541. PMID 15902304 DOI: 10.1172/Jci23780  0.737
2005 Zhu H, Traver D, Davidson AJ, Dibiase A, Thisse C, Thisse B, Nimer S, Zon LI. Regulation of the lmo2 promoter during hematopoietic and vascular development in zebrafish. Developmental Biology. 281: 256-69. PMID 15893977 DOI: 10.1016/J.Ydbio.2005.01.034  0.449
2005 Akashi K, Traver D, Zon LI. The complex cartography of stem cell commitment. Cell. 121: 160-2. PMID 15851023 DOI: 10.1016/J.Cell.2005.04.005  0.397
2005 Weber GJ, Choe SE, Dooley KA, Paffett-Lugassy NN, Zhou Y, Zon LI. Mutant-specific gene programs in the zebrafish. Blood. 106: 521-30. PMID 15827125 DOI: 10.1182/Blood-2004-11-4541  0.832
2005 Langenau DM, Zon LI. The zebrafish: a new model of T-cell and thymic development. Nature Reviews. Immunology. 5: 307-17. PMID 15803150 DOI: 10.1038/Nri1590  0.388
2005 Schönberger J, Wang L, Shin JT, Kim SD, Depreux FF, Zhu H, Zon L, Pizard A, Kim JB, Macrae CA, Mungall AJ, Seidman JG, Seidman CE. Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss. Nature Genetics. 37: 418-22. PMID 15735644 DOI: 10.1038/Ng1527  0.311
2005 Patton EE, Widlund HR, Kutok JL, Kopani KR, Amatruda JF, Murphey RD, Berghmans S, Mayhall EA, Traver D, Fletcher CD, Aster JC, Granter SR, Look AT, Lee C, Fisher DE, ... Zon LI, et al. BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Current Biology : Cb. 15: 249-54. PMID 15694309 DOI: 10.1016/J.Cub.2005.01.031  0.796
2005 Zon LI, Peterson RT. In vivo drug discovery in the zebrafish. Nature Reviews. Drug Discovery. 4: 35-44. PMID 15688071 DOI: 10.1038/Nrd1606  0.309
2005 Berghmans S, Murphey RD, Wienholds E, Neuberg D, Kutok JL, Fletcher CD, Morris JP, Liu TX, Schulte-Merker S, Kanki JP, Plasterk R, Zon LI, Look AT. tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors. Proceedings of the National Academy of Sciences of the United States of America. 102: 407-12. PMID 15630097 DOI: 10.1073/Pnas.0406252102  0.805
2005 Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI. Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos. Developmental Cell. 8: 109-16. PMID 15621534 DOI: 10.1016/J.Devcel.2004.12.001  0.822
2005 Dooley KA, Davidson AJ, Zon LI. Zebrafish scl functions independently in hematopoietic and endothelial development. Developmental Biology. 277: 522-36. PMID 15617691 DOI: 10.1016/J.Ydbio.2004.09.004  0.438
2005 Bahary N, Davidson A, Ransom D, Shepard J, Stern H, Trede N, Zhou Y, Barut B, Zon LI. The Zon laboratory guide to positional cloning in zebrafish. Methods in Cell Biology. 77: 305-29. PMID 15602919 DOI: 10.1016/S0091-679X(04)77017-X  0.75
2005 Mayhall EA, Paffett-Lugassy N, Zon LI. The clinical potential of stem cells. Current Opinion in Cell Biology. 16: 713-20. PMID 15530786 DOI: 10.1016/J.Ceb.2004.09.007  0.818
2005 Paffett-Lugassy NN, Zon LI. Analysis of hematopoietic development in the zebrafish. Methods in Molecular Medicine. 105: 171-98. PMID 15492396 DOI: 10.1385/1-59259-826-9:171  0.83
2005 Weber GJ, Chiang K, Mayhall EA, Zhou Y, Zon LI. Gene Expression Profiling of Hematopoietic Stem and Progenitor Cells in Zebrafish. Blood. 106: 3622-3622. DOI: 10.1182/Blood.V106.11.3622.3622  0.504
2005 Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI. Gata-Independent Regulation of Red Cell Specific Gene Expression. Blood. 106: 1736-1736. DOI: 10.1182/Blood.V106.11.1736.1736  0.812
2005 Wingert RA, Galloway JL, Barut B, Foott H, Fraenkel P, Axe JL, Weber GJ, Dooley K, Davidson AJ, Schmid B, Paw BH, Shaw GC, Kingsley P, Palis J, Schubert H, ... ... Zon LI, et al. Erratum: Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis (Nature (2005) 436 (1035-1039)) Nature. 437. DOI: 10.1038/Nature04218  0.748
2005 Gardiner MR, Daggett DF, Amacher SL, Currie PD, Zon LI, Perkins AC. Zebrafish KLF4 is essential for hatching and haematopoiesis Developmental Biology. 283: 619-619. DOI: 10.1016/J.Ydbio.2005.04.040  0.37
2004 Wingert RA, Brownlie A, Galloway JL, Dooley K, Fraenkel P, Axe JL, Davidson AJ, Barut B, Noriega L, Sheng X, Zhou Y, Zon LI. The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1. Development (Cambridge, England). 131: 6225-35. PMID 15563524 DOI: 10.1242/Dev.01540  0.804
2004 Ernst P, Mabon M, Davidson AJ, Zon LI, Korsmeyer SJ. An Mll-dependent Hox program drives hematopoietic progenitor expansion. Current Biology : Cb. 14: 2063-9. PMID 15556871 DOI: 10.1016/J.Cub.2004.11.012  0.439
2004 Song HD, Sun XJ, Deng M, Zhang GW, Zhou Y, Wu XY, Sheng Y, Chen Y, Ruan Z, Jiang CL, Fan HY, Zon LI, Kanki JP, Liu TX, Look AT, et al. Hematopoietic gene expression profile in zebrafish kidney marrow. Proceedings of the National Academy of Sciences of the United States of America. 101: 16240-5. PMID 15520368 DOI: 10.1073/Pnas.0407241101  0.425
2004 Davidson AJ, Zon LI. The 'definitive' (and 'primitive') guide to zebrafish hematopoiesis. Oncogene. 23: 7233-46. PMID 15378083 DOI: 10.1038/Sj.Onc.1207943  0.482
2004 Ransom DG, Bahary N, Niss K, Traver D, Burns C, Trede NS, Paffett-Lugassy N, Saganic WJ, Lim CA, Hersey C, Zhou Y, Barut BA, Lin S, Kingsley PD, Palis J, ... ... Zon LI, et al. The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. Plos Biology. 2: E237. PMID 15314655 DOI: 10.1371/Journal.Pbio.0020237  0.841
2004 Gong HY, Lin CJ, Chen MH, Hu MC, Lin GH, Zhou Y, Zon LI, Wu JL. Two distinct teleost hepatocyte nuclear factor 1 genes, hnf1alpha/tcf1 and hnf1beta/tcf2, abundantly expressed in liver, pancreas, gut and kidney of zebrafish. Gene. 338: 35-46. PMID 15302404 DOI: 10.1016/J.Gene.2004.05.003  0.348
2004 Bovenkamp DE, Goishi K, Bahary N, Davidson AJ, Zhou Y, Becker T, Becker CG, Zon LI, Klagsbrun M. Expression and mapping of duplicate neuropilin-1 and neuropilin-2 genes in developing zebrafish. Gene Expression Patterns : Gep. 4: 361-70. PMID 15183302 DOI: 10.1016/J.Modgep.2004.01.014  0.345
2004 Traver D, Winzeler A, Stern HM, Mayhall EA, Langenau DM, Kutok JL, Look AT, Zon LI. Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation. Blood. 104: 1298-305. PMID 15142873 DOI: 10.1182/Blood-2004-01-0100  0.392
2004 Langenau DM, Ferrando AA, Traver D, Kutok JL, Hezel JP, Kanki JP, Zon LI, Look AT, Trede NS. In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 101: 7369-74. PMID 15123839 DOI: 10.1073/Pnas.0402248101  0.342
2004 Hsu K, Traver D, Kutok JL, Hagen A, Liu TX, Paw BH, Rhodes J, Berman JN, Zon LI, Kanki JP, Look AT. The pu.1 promoter drives myeloid gene expression in zebrafish. Blood. 104: 1291-7. PMID 14996705 DOI: 10.1182/Blood-2003-09-3105  0.468
2004 Wingert RA, Barut B, Foott H, Fraenkel P, Dooley K, Kingsley P, Palis J, Shubert H, Chen O, Kaplan J, Zon LI. The Zebrafish Hypochromic Mutant [iItalic]Shiraz[/iItalic] Encodes a Novel Mitochondrial Glutaredoxin That Establishes a Link between Heme and Fe/S Production. Blood. 104: 51-51. DOI: 10.1182/Blood.V104.11.51.51  0.622
2004 Paw BH, Shaw GC, Cope JJ, Corson K, Hersey C, Wingert R, Ackermann GE, Traver D, Trede NS, Barut BA, Zon LI. Frascati , a Mitochondrial Solute Transporter, and Its Role in Vertebrate Erythropoiesis. Blood. 104: 49-49. DOI: 10.1182/Blood.V104.11.49.49  0.669
2004 Burns CE, Zon LI. Notch Signaling Is Necessary and Sufficient for Runx1-Dependent Stem Cell Induction in the Embryonic Aorta-Gonad-Mesonephros (AGM) Region. Blood. 104: 4161-4161. DOI: 10.1182/Blood.V104.11.4161.4161  0.47
2004 Fraenkel PG, Traver D, Donovan A, Zon LI. Ferroportin1-Deficient Zebrafish Treated with Iron Dextran Develop Anemia Despite Increased Macrophage Iron Stores. Blood. 104: 3691-3691. DOI: 10.1182/Blood.V104.11.3691.3691  0.742
2004 Galloway JL, Thisse C, Zhou Y, Beltre R, Thisse B, Zon LI. Conversion of Erythropoiesis to Myelopoiesis in Gata1-Deficient Zebrafish Embryos. Blood. 104: 2774-2774. DOI: 10.1182/Blood.V104.11.2774.2774  0.773
2004 Wang Y, Yates F, Dikovskaia E, Ernst P, Davidson AJ, Zon LI, Daley GQ. Derivation of Hematopoietic Stem Cells from Embryonic Stem Cells. Blood. 104: 223-223. DOI: 10.1182/Blood.V104.11.223.223  0.473
2004 Davidson AJ, Wang Y, Daley GQ, Zon LI. Inhibition of Retinoic Acid Signaling by the cdx-hox Pathway Is Essential for Blood Cell Formation during Embryogenesis. Blood. 104: 134-134. DOI: 10.1182/Blood.V104.11.134.134  0.395
2003 Traver D, Herbomel P, Patton EE, Murphey RD, Yoder JA, Litman GW, Catic A, Amemiya CT, Zon LI, Trede NS. The zebrafish as a model organism to study development of the immune system. Advances in Immunology. 81: 253-330. PMID 14711058 DOI: 10.1016/S0065-2776(03)81007-6  0.8
2003 Traver D, Paw BH, Poss KD, Penberthy WT, Lin S, Zon LI. Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nature Immunology. 4: 1238-46. PMID 14608381 DOI: 10.1038/Ni1007  0.444
2003 North TE, Zon LI. Modeling human hematopoietic and cardiovascular diseases in zebrafish. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 228: 568-83. PMID 14579393 DOI: 10.1002/Dvdy.10393  0.389
2003 Davidson AJ, Ernst P, Wang Y, Dekens MP, Kingsley PD, Palis J, Korsmeyer SJ, Daley GQ, Zon LI. cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes. Nature. 425: 300-6. PMID 13679919 DOI: 10.1038/Nature01973  0.458
2003 Piotrowski T, Ahn DG, Schilling TF, Nair S, Ruvinsky I, Geisler R, Rauch GJ, Haffter P, Zon LI, Zhou Y, Foott H, Dawid IB, Ho RK. The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans. Development (Cambridge, England). 130: 5043-52. PMID 12952905 DOI: 10.1242/Dev.00704  0.379
2003 Ward AC, McPhee DO, Condron MM, Varma S, Cody SH, Onnebo SM, Paw BH, Zon LI, Lieschke GJ. The zebrafish spi1 promoter drives myeloid-specific expression in stable transgenic fish. Blood. 102: 3238-40. PMID 12869502 DOI: 10.1182/Blood-2003-03-0966  0.426
2003 Stern HM, Zon LI. Cancer genetics and drug discovery in the zebrafish. Nature Reviews. Cancer. 3: 533-9. PMID 12835673 DOI: 10.1038/Nrc1126  0.331
2003 Paw BH, Davidson AJ, Zhou Y, Li R, Pratt SJ, Lee C, Trede NS, Brownlie A, Donovan A, Liao EC, Ziai JM, Drejer AH, Guo W, Kim CH, Gwynn B, ... ... Zon LI, et al. Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nature Genetics. 34: 59-64. PMID 12669066 DOI: 10.1038/Ng1137  0.78
2003 Guyon JR, Mosley AN, Zhou Y, O'Brien KF, Sheng X, Chiang K, Davidson AJ, Volinski JM, Zon LI, Kunkel LM. The dystrophin associated protein complex in zebrafish. Human Molecular Genetics. 12: 601-15. PMID 12620966 DOI: 10.1093/Hmg/Ddg071  0.323
2003 Brownlie A, Hersey C, Oates AC, Paw BH, Falick AM, Witkowska HE, Flint J, Higgs D, Jessen J, Bahary N, Zhu H, Lin S, Zon L. Characterization of embryonic globin genes of the zebrafish. Developmental Biology. 255: 48-61. PMID 12618133 DOI: 10.1016/S0012-1606(02)00041-6  0.401
2003 Langenau DM, Traver D, Ferrando AA, Kutok JL, Aster JC, Kanki JP, Lin S, Prochownik E, Trede NS, Zon LI, Look AT. Myc-induced T cell leukemia in transgenic zebrafish. Science (New York, N.Y.). 299: 887-90. PMID 12574629 DOI: 10.1126/Science.1080280  0.42
2003 Galloway JL, Zon LI. Ontogeny of hematopoiesis: examining the emergence of hematopoietic cells in the vertebrate embryo. Current Topics in Developmental Biology. 53: 139-58. PMID 12510667 DOI: 10.1016/S0070-2153(03)53004-6  0.745
2003 Langenau DM, Palomero T, Kanki JP, Ferrando AA, Zhou Y, Zon LI, Look AT. Molecular cloning and developmental expression of Tlx (Hox11) genes in zebrafish (Danio rerio). Mechanisms of Development. 117: 243-8. PMID 12204264 DOI: 10.1016/S0925-4773(02)00187-9  0.352
2003 Dooley KA, Zon LI. ESCs and hematopoietic fate: mixing the perfect “cocktail” Blood. 102: 776-776. DOI: 10.1182/Blood-2003-05-1736  0.393
2002 Burns CE, DeBlasio T, Zhou Y, Zhang J, Zon L, Nimer SD. Isolation and characterization of runxa and runxb, zebrafish members of the runt family of transcriptional regulators. Experimental Hematology. 30: 1381-9. PMID 12482499 DOI: 10.1016/S0301-472X(02)00955-4  0.474
2002 Burns CE, Zon LI. Portrait of a stem cell. Developmental Cell. 3: 612-3. PMID 12431368 DOI: 10.1016/S1534-5807(02)00329-5  0.382
2002 Best JL, Ganiatsas S, Agarwal S, Changou A, Salomoni P, Shirihai O, Meluh PB, Pandolfi PP, Zon LI. SUMO-1 protease-1 regulates gene transcription through PML. Molecular Cell. 10: 843-55. PMID 12419228 DOI: 10.1016/S1097-2765(02)00699-8  0.341
2002 Donovan A, Brownlie A, Dorschner MO, Zhou Y, Pratt SJ, Paw BH, Phillips RB, Thisse C, Thisse B, Zon LI. The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1). Blood. 100: 4655-9. PMID 12393445 DOI: 10.1182/Blood-2002-04-1169  0.766
2002 Pratt SJ, Drejer A, Foott H, Barut B, Brownlie A, Postlethwait J, Kato Y, Yamamoto M, Zon LI. Isolation and characterization of zebrafish NFE2. Physiological Genomics. 11: 91-8. PMID 12388799 DOI: 10.1152/Physiolgenomics.00112.2001  0.456
2002 Murphey RD, Zon LI. Attack of the fish clones. Nature Biotechnology. 20: 785-6. PMID 12148002 DOI: 10.1038/Nbt0802-785  0.791
2002 Lee P, Goishi K, Davidson AJ, Mannix R, Zon L, Klagsbrun M. Neuropilin-1 is required for vascular development and is a mediator of VEGF-dependent angiogenesis in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 99: 10470-5. PMID 12142468 DOI: 10.1073/Pnas.162366299  0.327
2002 Amatruda JF, Shepard JL, Stern HM, Zon LI. Zebrafish as a cancer model system. Cancer Cell. 1: 229-31. PMID 12086858 DOI: 10.1016/S1535-6108(02)00052-1  0.734
2002 Lieschke GJ, Oates AC, Paw BH, Thompson MA, Hall NE, Ward AC, Ho RK, Zon LI, Layton JE. Zebrafish SPI-1 (PU.1) marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning. Developmental Biology. 246: 274-95. PMID 12051816 DOI: 10.1006/Dbio.2002.0657  0.461
2002 Orkin SH, Zon LI. Hematopoiesis and stem cells: Plasticity versus development heterogeneity Nature Immunology. 3: 323-328. PMID 11919568 DOI: 10.1038/Ni0402-323  0.548
2002 Liao EC, Trede NS, Ransom D, Zapata A, Kieran M, Zon LI. Non-cell autonomous requirement for the bloodless gene in primitive hematopoiesis of zebrafish. Development (Cambridge, England). 129: 649-59. PMID 11830566  0.373
2002 Thisse C, Zon LI. Organogenesis--heart and blood formation from the zebrafish point of view. Science (New York, N.Y.). 295: 457-62. PMID 11799232 DOI: 10.1126/Science.1063654  0.351
2002 Paffett-Lugassy N, Zon LI. Epo-EpoR signaling not required for cardiovascular or neural development Blood. 100: 2277-2277. DOI: 10.1182/Blood-2002-07-2279  0.815
2001 Lyons SE, Shue BC, Lei L, Oates AC, Zon LI, Liu PP. Molecular cloning, genetic mapping, and expression analysis of four zebrafish c/ebp genes. Gene. 281: 43-51. PMID 11750126 DOI: 10.1016/S0378-1119(01)00774-0  0.339
2001 Patton EE, Zon LI. The art and design of genetic screens: zebrafish. Nature Reviews. Genetics. 2: 956-66. PMID 11733748 DOI: 10.1038/35103567  0.353
2001 Bahary N, Zon LI. Development. Endothelium--chicken soup for the endoderm. Science (New York, N.Y.). 294: 530-1. PMID 11577202 DOI: 10.1126/Science.1066282  0.325
2001 Huber TL, Perkins AC, Deconinck AE, Chan FY, Mead PE, Zon LI. neptune, a Krüppel-like transcription factor that participates in primitive erythropoiesis in Xenopus. Current Biology : Cb. 11: 1456-61. PMID 11566106 DOI: 10.1016/S0960-9822(01)00427-4  0.584
2001 Moretti PA, Davidson AJ, Baker E, Lilley B, Zon LI, D'Andrea RJ. Molecular cloning of a human Vent-like homeobox gene. Genomics. 76: 21-9. PMID 11549314 DOI: 10.1006/Geno.2001.6574  0.347
2001 Oates AC, Pratt SJ, Vail B, Yan Yl, Ho RK, Johnson SL, Postlethwait JH, Zon LI. The zebrafish klf gene family. Blood. 98: 1792-801. PMID 11535513 DOI: 10.1182/Blood.V98.6.1792  0.397
2001 Mead PE, Deconinck AE, Huber TL, Orkin SH, Zon LI. Primitive erythropoiesis in the Xenopus embryo: the synergistic role of LMO-2, SCL and GATA-binding proteins. Development (Cambridge, England). 128: 2301-8. PMID 11493549  0.638
2001 Bennett CM, Kanki JP, Rhodes J, Liu TX, Paw BH, Kieran MW, Langenau DM, Delahaye-Brown A, Zon LI, Fleming MD, Look AT. Myelopoiesis in the zebrafish, Danio rerio. Blood. 98: 643-51. PMID 11468162 DOI: 10.1182/Blood.V98.3.643  0.463
2001 Trede NS, Zapata A, Zon LI. Fishing for lymphoid genes. Trends in Immunology. 22: 302-7. PMID 11377288 DOI: 10.1016/S1471-4906(01)01939-1  0.396
2001 Hamazaki T, Iiboshi Y, Oka M, Papst PJ, Meacham AM, Zon LI, Terada N. Hepatic maturation in differentiating embryonic stem cells in vitro. Febs Letters. 497: 15-9. PMID 11376655 DOI: 10.1016/S0014-5793(01)02423-1  0.4
2001 Lyons SE, Shue BC, Oates AC, Zon LI, Liu PP. A novel myeloid-restricted zebrafish CCAAT/enhancer-binding protein with a potent transcriptional activation domain. Blood. 97: 2611-7. PMID 11313249 DOI: 10.1182/Blood.V97.9.2611  0.337
2001 Chayama K, Papst PJ, Garrington TP, Pratt JC, Ishizuka T, Webb S, Ganiatsas S, Zon LI, Sun W, Johnson GL, Gelfand EW. Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 4599-604. PMID 11274363 DOI: 10.1073/Pnas.081021898  0.327
2001 Zon LI. Self-renewal versus differentiation, a job for the mighty morphogens. Nature Immunology. 2: 142-3. PMID 11175810 DOI: 10.1038/84239  0.386
2001 Miyoshi K, Cui Y, Riedlinger G, Robinson P, Lehoczky J, Zon L, Oka T, Dewar K, Hennighausen L. Structure of the mouse Stat 3/5 locus: Evolution from Drosophila to zebrafish to mouse Genomics. 71: 150-155. PMID 11161808 DOI: 10.1006/Geno.2000.6433  0.308
2000 Blake T, Adya N, Kim CH, Oates AC, Zon L, Chitnis A, Weinstein BM, Liu PP. Zebrafish homolog of the leukemia gene CBFB: its expression during embryogenesis and its relationship to scl and gata-1 in hematopoiesis. Blood. 96: 4178-84. PMID 11110689 DOI: 10.1182/Blood.V96.13.4178  0.438
2000 Bahary N, Zon LI. Use of the zebrafish (Danio rerio) to define hematopoiesis. Stem Cells (Dayton, Ohio). 67-78. PMID 11012178 DOI: 10.1002/stem.5530160709  0.363
2000 White RA, Pasztor LM, Richardson PM, Zon LI. The gene encoding TBC1D1 with homology to the tre-2/USP6 oncogene, BUB2, and cdc16 maps to mouse chromosome 5 and human chromosome 4. Cytogenetics and Cell Genetics. 89: 272-5. PMID 10965142 DOI: 10.1159/000015632  0.304
2000 Davidson AJ, Zon LI. Turning mesoderm into blood: the formation of hematopoietic stem cells during embryogenesis. Current Topics in Developmental Biology. 50: 45-60. PMID 10948449 DOI: 10.1016/S0070-2153(00)50003-9  0.455
2000 Tsai M, Wedemeyer J, Ganiatsas S, Tam SY, Zon LI, Galli SJ. In vivo immunological function of mast cells derived from embryonic stem cells: an approach for the rapid analysis of even embryonic lethal mutations in adult mice in vivo. Proceedings of the National Academy of Sciences of the United States of America. 97: 9186-90. PMID 10908668 DOI: 10.1073/Pnas.160254997  0.459
2000 Dooley K, Zon LI. Zebrafish: A model system for the study of human disease Current Opinion in Genetics and Development. 10: 252-256. PMID 10826982 DOI: 10.1016/S0959-437X(00)00074-5  0.334
2000 Deconinck AE, Mead PE, Tevosian SG, Crispino JD, Katz SG, Zon LI, Orkin SH. FOG acts as a repressor of red blood cell development in Xenopus Development. 127: 2031-2040. PMID 10769228  0.676
2000 Paw BH, Zon LI. Zebrafish: a genetic approach in studying hematopoiesis. Current Opinion in Hematology. 7: 79-84. PMID 10698293 DOI: 10.1097/00062752-200003000-00002  0.406
2000 Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law TC, Brugnara C, Lux SE, Pinkus GS, Pinkus JL, ... ... Zon LI, et al. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature. 403: 776-81. PMID 10693807 DOI: 10.1038/35001596  0.774
2000 Shepard JL, Zon LI. Developmental derivation of embryonic and adult macrophages. Current Opinion in Hematology. 7: 3-8. PMID 10608497 DOI: 10.1097/00062752-200001000-00002  0.758
2000 Amatruda JF, Zon LI. Dissecting hematopoiesis and disease using the zebrafish. Developmental Biology. 216: 1-15. PMID 10588859 DOI: 10.1006/Dbio.1999.9462  0.492
2000 Blake T, Adya N, Kim C, Oates AC, Zon L, Chitnis A, Weinstein BM, Liu PP. Zebrafish homolog of the leukemia gene CBFB: its expression during embryogenesis and its relationship to scland gata-1 in hematopoiesis Blood. 96: 4178-4184. DOI: 10.1182/BLOOD.V96.13.4178  0.325
1999 Oates AC, Brownlie A, Pratt SJ, Irvine DV, Liao EC, Paw BH, Dorian KJ, Johnson SL, Postlethwait JH, Zon LI, Wilks AF. Gene duplication of zebrafish JAK2 homologs is accompanied by divergent embryonic expression patterns: only jak2a is expressed during erythropoiesis. Blood. 94: 2622-36. PMID 10515866 DOI: 10.1182/Blood.V94.8.2622.420K39_2622_2636  0.408
1999 Porcher C, Liao EC, Fujiwara Y, Zon LI, Orkin SH. Specification of hematopoietic and vascular development by the bHLH transcription factor SCL without direct DNA binding. Development (Cambridge, England). 126: 4603-15. PMID 10498694  0.452
1999 Hukriede NA, Joly L, Tsang M, Miles J, Tellis P, Epstein JA, Barbazuk WB, Li FN, Paw B, Postlethwait JH, Hudson TJ, Zon LI, McPherson JD, Chevrette M, Dawid IB, et al. Radiation hybrid mapping of the zebrafish genome. Proceedings of the National Academy of Sciences of the United States of America. 96: 9745-50. PMID 10449765 DOI: 10.1073/Pnas.96.17.9745  0.317
1999 Oates AC, Wollberg P, Pratt SJ, Paw BH, Johnson SL, Ho RK, Postlethwait JH, Zon LI, Wilks AF. Zebrafish stat3 is expressed in restricted tissues during embryogenesis and stat1 rescues cytokine signaling in a STAT1-deficient human cell line. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 215: 352-70. PMID 10417824 DOI: 10.1002/(Sici)1097-0177(199908)215:4<352::Aid-Aja7>3.0.Co;2-J  0.384
1999 Parker LH, Zon LI, Stainier DYR. Vascular and blood gene expression Methods in Cell Biology. 313-336. PMID 9891367 DOI: 10.1016/S0091-679X(08)61832-4  0.415
1999 Paw BH, Zon LI. Primary fibroblast cell culture. Methods in Cell Biology. 59: 39-43. PMID 9891354 DOI: 10.1016/S0091-679X(08)61819-1  0.347
1999 Detrich HW, Westerfield M, Zon LI. Overview of the Zebrafish system. Methods in Cell Biology. 59: 3-10. PMID 9891351 DOI: 10.1016/S0091-679X(08)61816-6  0.449
1999 Amemiya CT, Zhong TP, Silverman GA, Fishman MC, Zon LI. Zebrafish YAC, BAC, and PAC genomic libraries. Methods in Cell Biology. 60: 235-58. PMID 9891341 DOI: 10.1016/S0091-679X(08)61904-4  0.323
1999 Zon LI. Zebrafish: A New Model for Human Disease Genome Research. 9: 99-100. DOI: 10.1101/Gr.9.2.99  0.359
1998 Brownlie A, Donovan A, Pratt SJ, Paw BH, Oates AC, Brugnara C, Witkowska HE, Sassa S, Zon LI. Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia. Nature Genetics. 20: 244-50. PMID 9806542 DOI: 10.1038/3049  0.751
1998 Lee KH, Marden JJ, Thompson MS, Maclennan H, Kishimoto Y, Pratt SJ, Schulte-Merker S, Hammerschmidt M, Johnson SL, Postlethwaite JH, Beier DC, Zon LI. Cloning and genetic mapping of zebrafish BMP-2 Developmental Genetics. 23: 97-103. PMID 9770266 DOI: 10.1002/(Sici)1520-6408(1998)23:2<97::Aid-Dvg1>3.0.Co;2-0  0.398
1998 Mead PE, Zhou Y, Lustig KD, Huber TL, Kirschner MW, Zon LI. Cloning of Mix-related homeodomain proteins using fast retrieval of gel shift activities, (FROGS), a technique for the isolation of DNA-binding proteins. Proceedings of the National Academy of Sciences of the United States of America. 95: 11251-6. PMID 9736722 DOI: 10.1073/Pnas.95.19.11251  0.532
1998 Alberola-lla J, Levin SD, Barton G, Forbush K, Zon LI, Perlmutter RM. Analysis of the pole of MKK-4/Sek-1 in T cell development and apoptosis International Immunology. 10: 1077-1082. PMID 9723693 DOI: 10.1093/Intimm/10.8.1077  0.329
1998 Trede NS, Zon LI. Development of T-cells during fish embryogenesis. Developmental and Comparative Immunology. 22: 253-63. PMID 9700456 DOI: 10.1016/S0145-305X(98)00009-3  0.366
1998 Thompson MA, Ransom DG, Pratt SJ, MacLennan H, Kieran MW, Detrich HW, Vail B, Huber TL, Paw B, Brownlie AJ, Oates AC, Fritz A, Gates MA, Amores A, Bahary N, ... ... Zon LI, et al. The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis. Developmental Biology. 197: 248-69. PMID 9630750 DOI: 10.1006/Dbio.1998.8887  0.633
1998 Swat W, Fujikawa K, Ganiatsas S, Yang D, Xavier RJ, Harris NL, Davidson L, Ferrini R, Davis RJ, Labow MA, Flavell RA, Zon LI, Alt FW. SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development. Immunity. 8: 625-34. PMID 9620683 DOI: 10.1016/S1074-7613(00)80567-1  0.37
1998 Huber TL, Zon LI. Transcriptional regulation of blood formation during Xenopus development. Seminars in Immunology. 10: 103-9. PMID 9618755 DOI: 10.1006/Smim.1998.0111  0.587
1998 Ganiatsas S, Kwee L, Fujiwara Y, Perkins A, Ikeda T, Labow MA, Zon LI. SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis. Proceedings of the National Academy of Sciences of the United States of America. 95: 6881-6. PMID 9618507 DOI: 10.1073/Pnas.95.12.6881  0.351
1998 Mead PE, Zon LI. Molecular insights into early hematopoiesis. Current Opinion in Hematology. 5: 156-60. PMID 9570710 DOI: 10.1097/00062752-199803000-00012  0.42
1998 Jessen JR, Meng A, McFarlane RJ, Paw BH, Zon LI, Smith GR, Lin S. Modification of bacterial artificial chromosomes through chi-stimulated homologous recombination and its application in zebrafish transgenesis. Proceedings of the National Academy of Sciences of the United States of America. 95: 5121-6. PMID 9560239 DOI: 10.1073/Pnas.95.9.5121  0.357
1998 Bahary N, Zon LI. Use of the zebrafish (Danio rerio) to define hematopoiesis. Stem Cells (Dayton, Ohio). 16: 89-98. PMID 9554032 DOI: 10.1002/Stem.160089  0.469
1998 Postlethwait JH, Yan YL, Gates MA, Horne S, Amores A, Brownlie A, Donovan A, Egan ES, Force A, Gong Z, Goutel C, Fritz A, Kelsh R, Knapik E, Liao E, ... ... Zon LI, et al. Vertebrate genome evolution and the zebrafish gene map. Nature Genetics. 18: 345-9. PMID 9537416 DOI: 10.1038/Ng0498-345  0.746
1998 Liao EC, Paw BH, Oates AC, Pratt SJ, Postlethwait JH, Zon LI. SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish. Genes & Development. 12: 621-6. PMID 9499398 DOI: 10.1101/Gad.12.5.621  0.446
1998 Huber TL, Zhou Y, Mead PE, Zon LI. Cooperative Effects of Growth Factors Involved in the Induction of Hematopoietic Mesoderm Blood. 92: 4128-4137. DOI: 10.1182/Blood.V92.11.4128.423K46_4128_4137  0.602
1998 Yamaguchi Y, Zon LI, Ackerman SJ, Yamamoto M, Suda T. Forced GATA-1 Expression in the Murine Myeloid Cell Line M1: Induction of c-Mpl Expression and Megakaryocytic/Erythroid Differentiation Blood. 91: 450-457. DOI: 10.1182/Blood.V91.2.450.450_450_457  0.388
1997 Orkin SH, Zon LI. Genetics of erythropoiesis: Induced mutations in mice and zebrafish Annual Review of Genetics. 31: 33-60. PMID 9442889 DOI: 10.1146/Annurev.Genet.31.1.33  0.608
1997 Kieran MW, Zon LI. Stress- and mitogen-activated signal transduction in hematopoietic cells. Current Opinion in Hematology. 3: 27-34. PMID 9372048 DOI: 10.1097/00062752-199603010-00005  0.346
1997 Turpen JB, Kelley CM, Mead PE, Zon LI. Bipotential primitive-definitive hematopoietic progenitors in the vertebrate embryo. Immunity. 7: 325-34. PMID 9324353 DOI: 10.1016/S1074-7613(00)80354-4  0.424
1997 Lustig KD, Stukenberg PT, McGarry TJ, King RW, Cryns VL, Mead PE, Zon LI, Yuan J, Kirschner MW. Small pool expression screening: identification of genes involved in cell cycle control, apoptosis, and early development. Methods in Enzymology. 283: 83-99. PMID 9251013 DOI: 10.1016/S0076-6879(97)83009-1  0.401
1997 Molnár A, Theodoras AM, Zon LI, Kyriakis JM. Cdc42Hs, but not Rac1, inhibits serum-stimulated cell cycle progression at G1/S through a mechanism requiring p38/RK. The Journal of Biological Chemistry. 272: 13229-35. PMID 9148940 DOI: 10.1074/Jbc.272.20.13229  0.324
1997 Chan FY, Robinson J, Brownlie A, Shivdasani RA, Donovan A, Brugnara C, Kim J, Lau BC, Witkowska HE, Zon LI. Characterization of adult alpha- and beta-globin genes in the zebrafish. Blood. 89: 688-700. PMID 9002973  0.749
1997 Pestell RG, Albanese C, Watanabe G, Lee RJ, Lastowiecki P, Zon L, Ostrowski M, Jameson JL. Stimulation of the P-450 side chain cleavage enzyme (CYP11A1) promoter through ras- and Ets-2-signaling pathways. Molecular Endocrinology (Baltimore, Md.). 10: 1084-94. PMID 8885243 DOI: 10.1210/Mend.10.9.8885243  0.301
1997 Chan F, Robinson J, Brownlie A, Shivdasani RA, Donovan A, Brugnara C, Kim J, Lau B, Witkowska HE, Zon LI. Characterization of Adult α- and β-Globin Genes in the Zebrafish Blood. 89: 688-700. DOI: 10.1182/Blood.V89.2.688  0.355
1996 Zanke BW, Boudreau K, Rubie E, Winnett E, Tibbles LA, Zon L, Kyriakis J, Liu FF, Woodgett JR. The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat Current Biology. 6: 606-613. PMID 8805279 DOI: 10.1016/S0960-9822(02)00547-X  0.329
1996 Kieran MW, Perkins AC, Orkin SH, Zon LI. Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor. Proceedings of the National Academy of Sciences of the United States of America. 93: 9126-31. PMID 8799165 DOI: 10.1073/Pnas.93.17.9126  0.525
1996 Bishop TR, Miller MW, Beall J, Zon LI, Dierks P. Genetic regulation of delta-aminolevulinate dehydratase during erythropoiesis. Nucleic Acids Research. 24: 2511-8. PMID 8692689 DOI: 10.1093/Nar/24.13.2511  0.323
1996 Mead PE, Brivanlou IH, Kelley CM, Zon LI. BMP-4-responsive regulation of dorsal-ventral patterning by the homeobox protein Mix.1. Nature. 382: 357-60. PMID 8684465 DOI: 10.1038/382357A0  0.368
1996 Maeno M, Mead P, Kelley C, Xu R, Kung H, Suzuki A, Ueno N, Zon L. The role of BMP-4 and GATA-2 in the induction and differentiation of hematopoietic mesoderm in Xenopus laevis Blood. 88: 1965-1972. DOI: 10.1182/Blood.V88.6.1965.Bloodjournal8861965  0.403
1995 Detrich HW, Kieran MW, Chan FY, Barone LM, Yee K, Rundstadler JA, Pratt S, Ransom D, Zon LI. Intraembryonic hematopoietic cell migration during vertebrate development. Proceedings of the National Academy of Sciences of the United States of America. 92: 10713-7. PMID 7479870 DOI: 10.1073/Pnas.92.23.10713  0.447
1995 Pombo CM, Kehrl JH, Sánchez I, Katz P, Avruch J, Zon LI, Woodgett JR, Force T, Kyriakis JM. Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase Nature. 377: 750-754. PMID 7477268 DOI: 10.1038/377750A0  0.319
1995 Zon L. Developmental biology of hematopoiesis Blood. 86: 2876-2891. DOI: 10.1182/Blood.V86.8.2876.Bloodjournal8682876  0.412
1994 Kelley C, Yee K, Harland R, Zon LI. Ventral expression of GATA-1 and GATA-2 in the Xenopus embryo defines induction of hematopoietic mesoderm. Developmental Biology. 165: 193-205. PMID 8088437 DOI: 10.1006/Dbio.1994.1246  0.408
1993 Zon LI, Yamaguchi Y, Yee K, Albee EA, Kimura A, Bennett JC, Orkin SH, Ackerman SJ. Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription. Blood. 81: 3234-41. PMID 8507862 DOI: 10.1182/Blood.V81.12.3234.Bloodjournal81123234  0.495
1993 Yee K, Bishop T, Mather C, Zon L. Isolation of a novel receptor tyrosine kinase cDNA expressed by developing erythroid progenitors Blood. 82: 1335-1343. DOI: 10.1182/Blood.V82.4.1335.1335  0.354
1992 Sposi NM, Zon LI, Carè A, Valtieri M, Testa U, Gabbianelli M, Mariani G, Bottero L, Mather C, Orkin SH. Cell cycle-dependent initiation and lineage-dependent abrogation of GATA-1 expression in pure differentiating hematopoietic progenitors. Proceedings of the National Academy of Sciences of the United States of America. 89: 6353-7. PMID 1631130 DOI: 10.1073/Pnas.89.14.6353  0.588
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