John Hassell - Publications

Affiliations: 
McMaster University, Hamilton, ON, Canada 
Area:
Molecular Biology

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Gwynne WD, Shakeel MS, Girgis-Gabardo A, Hassell JA. The Role of Serotonin in Breast Cancer Stem Cells. Molecules (Basel, Switzerland). 26. PMID 34073226 DOI: 10.3390/molecules26113171  0.4
2020 Gwynne WD, Shakeel MS, Girgis-Gabardo A, Kim KH, Ford E, Dvorkin-Gheva A, Aarts C, Isaac M, Al-Awar R, Hassell JA. Antagonists of the serotonin receptor 5A target human breast tumor initiating cells. Bmc Cancer. 20: 724. PMID 32758183 DOI: 10.1186/s12885-020-07193-6  0.37
2019 Gwynne WD, Shakeel MS, Wu J, Hallett RM, Girgis-Gabardo A, Dvorkin-Gheva A, Hassell JA. Monoamine oxidase-A activity is required for clonal tumorsphere formation by human breast tumor cells. Cellular & Molecular Biology Letters. 24: 59. PMID 31754354 DOI: 10.1186/s11658-019-0183-8  0.375
2019 Atiya HI, Dvorkin-Gheva A, Hassell J, Patel S, Parker RL, Hartstone-Rose A, Hodge J, Fan D, Ramsdell AF. Intraductal Adaptation of the 4T1 Mouse Model of Breast Cancer Reveals Effects of the Epithelial Microenvironment on Tumor Progression and Metastasis. Anticancer Research. 39: 2277-2287. PMID 31092419 DOI: 10.21873/Anticanres.13344  0.463
2017 Shenouda MM, Gillgrass A, Nham T, Hogg R, Lee AJ, Chew MV, Shafaei M, Aarts C, Lee DA, Hassell J, Bane A, Dhesy-Thind S, Ashkar AA. Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived tumours. Breast Cancer Research : Bcr. 19: 76. PMID 28668076 DOI: 10.1186/S13058-017-0867-9  0.401
2017 Gwynne WD, Hallett RM, Girgis-Gabardo A, Bojovic B, Dvorkin-Gheva A, Aarts C, Dias K, Bane A, Hassell JA. Serotonergic system antagonists target breast tumor initiating cells and synergize with chemotherapy to shrink human breast tumor xenografts. Oncotarget. PMID 28404880 DOI: 10.18632/oncotarget.16646  0.383
2017 Bassey-Archibong BI, Rayner LG, Hercules SM, Aarts CW, Dvorkin-Gheva A, Bramson JL, Hassell JA, Daniel JM. Kaiso depletion attenuates the growth and survival of triple negative breast cancer cells. Cell Death & Disease. 8: e2689. PMID 28333150 DOI: 10.1038/cddis.2017.92  0.429
2017 Dias K, Dvorkin-Gheva A, Hallett RM, Wu Y, Hassell J, Pond GR, Levine M, Whelan T, Bane AL. Claudin-Low Breast Cancer; Clinical & Pathological Characteristics. Plos One. 12: e0168669. PMID 28045912 DOI: 10.1371/Journal.Pone.0168669  0.482
2017 Gillgrass A, Pond G, Levine M, Whelan T, Hassell J, Bane A. Abstract P4-12-09: The immune response in triple negative breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P4-12-09  0.417
2016 Hallett RM, Girgis-Gabardo A, Gwynne WD, Giacomelli AO, Bisson JN, Jensen JE, Dvorkin-Gheva A, Hassell JA. Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer. Oncotarget. PMID 27447971 DOI: 10.18632/oncotarget.10614  0.39
2016 Bassey-Archibong BI, Kwiecien JM, Milosavljevic SB, Hallett RM, Rayner LG, Erb MJ, Crawford-Brown CJ, Stephenson KB, Bédard PA, Hassell JA, Daniel JM. Kaiso depletion attenuates transforming growth factor-β signaling and metastatic activity of triple-negative breast cancer cells. Oncogenesis. 5: e208. PMID 26999717 DOI: 10.1038/oncsis.2016.17  0.385
2016 Gwynne W, Hallett R, Girgis-Gabardo A, Dvorkin-Gheva A, Hassell J. Serotonergic antagonists target breast tumor-initiating cells in mouse models of human breast cancer European Journal of Cancer. 69: S83. DOI: 10.1016/S0959-8049(16)32842-8  0.372
2015 Qazi MA, Vora P, Venugopal C, McFarlane N, Subapanditha MK, Murty NK, Hassell JA, Hallett RM, Singh SK. A novel stem cell culture model of recurrent glioblastoma. Journal of Neuro-Oncology. PMID 26498281 DOI: 10.1007/S11060-015-1951-6  0.327
2015 Robichaux JP, Hallett RM, Fuseler JW, Hassell JA, Ramsdell AF. Mammary glands exhibit molecular laterality and undergo left-right asymmetric ductal epithelial growth in MMTV-cNeu mice. Oncogene. 34: 2003-10. PMID 24909172 DOI: 10.1038/Onc.2014.149  0.387
2015 Jerzak KJ, Cockburn J, Pond GR, Hallett R, Hassell J, Pritchard KI, Dhesy-Thind SK, Bane A. Expression of thyroid hormone receptor alpha (THRα) isoforms in triple negative breast cancer (TNBC). Journal of Clinical Oncology. 33: e12082-e12082. DOI: 10.1200/Jco.2015.33.15_Suppl.E12082  0.4
2015 Li B, Hallet R, Wu Y, Pong G, Hassell J, Hotte S, Levine M, Lukka H, Bane A. Abstract 4346: Prognostic gene signature for intermediate risk prostate cancer Cancer Research. 75: 4346-4346. DOI: 10.1158/1538-7445.Am2015-4346  0.348
2015 Venugopal C, Hallett R, Vora P, Manoranjan B, Mahendram S, Qazi M, McFarlane N, Subapanditha M, Nolte S, Singh M, Bakhshinyan D, Garg N, Boleslaw L, John P, Reddy K, ... ... Hassell J, et al. STEM-23PYRVINIUM TARGETS CD133 IN HUMAN GLIOBLASTOMA BRAIN TUMOR-INITIATING CELLS Neuro-Oncology. 17: v213.1-v213. DOI: 10.1093/Neuonc/Nov234.23  0.352
2015 Singh M, Venugopal C, McFarlane N, Bakhshinyan D, Mahendram S, Brown K, Tong A, Durrer K, Hallett R, Hassell J, Moffat J, Singh S. BMET-31DEVELOPMENT AND APPLICATION OF A NOVEL MODEL OF HUMAN LUNG-TO-BRAIN METASTASIS TO IDENTIFY UNIQUE METASTATIC GENE SIGNATURES Neuro-Oncology. 17: v51.5-v52. DOI: 10.1093/Neuonc/Nov208.31  0.406
2015 Manoranjan B, Venugopal C, Mahendram S, Moreira S, Hallett R, Vijayakumar T, Bakhshinyan D, McFarlane N, Hassell J, Doble B, Singh S. MB-15 * ACTIVATED Wnt SIGNALING TARGETS Sox2+ TREATMENT-REFRACTORY Shh-DEPENDENT MEDULLOBLASTOMA STEM CELLS Neuro-Oncology. 17: iii23-iii23. DOI: 10.1093/Neuonc/Nov061.91  0.4
2014 Hallett RM, Hassell JA. Estrogen independent gene expression defines clinically relevant subgroups of estrogen receptor positive breast cancer. Bmc Cancer. 14: 871. PMID 25420785 DOI: 10.1186/1471-2407-14-871  0.38
2013 Manoranjan B, Wang X, Hallett RM, Venugopal C, Mack SC, McFarlane N, Nolte SM, Scheinemann K, Gunnarsson T, Hassell JA, Taylor MD, Lee C, Triscott J, Foster CM, Dunham C, et al. FoxG1 interacts with Bmi1 to regulate self-renewal and tumorigenicity of medulloblastoma stem cells. Stem Cells (Dayton, Ohio). 31: 1266-77. PMID 23592496 DOI: 10.1002/stem.1401  0.407
2013 Kurpios NA, Girgis-Gabardo A, Hallett RM, Rogers S, Gludish DW, Kockeritz L, Woodgett J, Cardiff R, Hassell JA. Single unpurified breast tumor-initiating cells from multiple mouse models efficiently elicit tumors in immune-competent hosts. Plos One. 8: e58151. PMID 23555570 DOI: 10.1371/Journal.Pone.0058151  0.352
2012 Hallett RM, Pond G, Hassell JA. A target based approach identifies genomic predictors of breast cancer patient response to chemotherapy. Bmc Medical Genomics. 5: 16. PMID 22578285 DOI: 10.1186/1755-8794-5-16  0.329
2012 Hallett RM, Kondratyev MK, Giacomelli AO, Nixon AM, Girgis-Gabardo A, Ilieva D, Hassell JA. Small molecule antagonists of the Wnt/β-catenin signaling pathway target breast tumor-initiating cells in a Her2/Neu mouse model of breast cancer. Plos One. 7: e33976. PMID 22470504 DOI: 10.1371/journal.pone.0033976  0.345
2012 Kondratyev M, Kreso A, Hallett RM, Girgis-Gabardo A, Barcelon ME, Ilieva D, Ware C, Majumder PK, Hassell JA. Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB2 breast cancer. Oncogene. 31: 93-103. PMID 21666715 DOI: 10.1038/onc.2011.212  0.366
2011 Dvorkin-Gheva A, Hassell JA. Hormone receptor and ERBB2 status in gene expression profiles of human breast tumor samples. Plos One. 6: e26023. PMID 22022496 DOI: 10.1371/journal.pone.0026023  0.413
2011 Hallett RM, Hassell JA. E2F1 and KIAA0191 expression predicts breast cancer patient survival. Bmc Research Notes. 4: 95. PMID 21453498 DOI: 10.1186/1756-0500-4-95  0.344
2010 Hebbard LW, Maurer J, Miller A, Lesperance J, Hassell J, Oshima RG, Terskikh AV. Maternal embryonic leucine zipper kinase is upregulated and required in mammary tumor-initiating cells in vivo. Cancer Research. 70: 8863-73. PMID 20861186 DOI: 10.1158/0008-5472.Can-10-1295  0.54
2010 Zhang Z, Sui P, Dong A, Hassell J, Cserjesi P, Chen YT, Behringer RR, Sun X. Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb. Development (Cambridge, England). 137: 3417-26. PMID 20826535 DOI: 10.1242/Dev.051789  0.402
2010 Hallett RM, Dvorkin A, Gabardo CM, Hassell JA. An algorithm to discover gene signatures with predictive potential. Journal of Experimental & Clinical Cancer Research : Cr. 29: 120. PMID 20813028 DOI: 10.1186/1756-9966-29-120  0.351
2010 Baker R, Kent CV, Silbermann RA, Hassell JA, Young LJ, Howe LR. Pea3 transcription factors and wnt1-induced mouse mammary neoplasia. Plos One. 5: e8854. PMID 20107508 DOI: 10.1371/journal.pone.0008854  0.476
2009 Lu BC, Cebrian C, Chi X, Kuure S, Kuo R, Bates CM, Arber S, Hassell J, MacNeil L, Hoshi M, Jain S, Asai N, Takahashi M, Schmidt-Ott KM, Barasch J, et al. Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis. Nature Genetics. 41: 1295-302. PMID 19898483 DOI: 10.1038/Ng.476  0.386
2009 Kurpios NA, MacNeil L, Shepherd TG, Gludish DW, Giacomelli AO, Hassell JA. The Pea3 Ets transcription factor regulates differentiation of multipotent progenitor cells during mammary gland development. Developmental Biology. 325: 106-21. PMID 18977342 DOI: 10.1016/J.Ydbio.2008.09.033  0.65
2005 Chen C, Ouyang W, Grigura V, Zhou Q, Carnes K, Lim H, Zhao GQ, Arber S, Kurpios N, Murphy TL, Cheng AM, Hassell JA, Chandrashekar V, Hofmann MC, Hess RA, et al. ERM is required for transcriptional control of the spermatogonial stem cell niche. Nature. 436: 1030-4. PMID 16107850 DOI: 10.1038/Nature03894  0.317
2005 Youn BS, Sen A, Kallos MS, Behie LA, Girgis-Gabardo A, Kurpios N, Barcelon M, Hassell JA. Large-scale expansion of mammary epithelial stem cell aggregates in suspension bioreactors. Biotechnology Progress. 21: 984-93. PMID 15932284 DOI: 10.1021/Bp050059F  0.322
2005 Hesselbrock DR, Kurpios N, Hassell JA, Watson MA, Fleming TP. PEA3, AP-1, and a unique repetitive sequence all are involved in transcriptional regulation of the breast cancer-associated gene, mammaglobin. Breast Cancer Research and Treatment. 89: 289-96. PMID 15754128 DOI: 10.1007/s10549-004-2622-z  0.352
2004 White DE, Kurpios NA, Zuo D, Hassell JA, Blaess S, Mueller U, Muller WJ. Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction. Cancer Cell. 6: 159-70. PMID 15324699 DOI: 10.1016/J.Ccr.2004.06.025  0.375
2004 Discenza MT, Vaz D, Hassell JA, Pelletier J. Activation of the WT1 tumor suppressor gene promoter by Pea3. Febs Letters. 560: 183-91. PMID 14988020 DOI: 10.1016/S0014-5793(04)00104-8  0.416
2003 Kurpios NA, Sabolic NA, Shepherd TG, Fidalgo GM, Hassell JA. Function of PEA3 Ets transcription factors in mammary gland development and oncogenesis. Journal of Mammary Gland Biology and Neoplasia. 8: 177-90. PMID 14635793 DOI: 10.1023/A:1025948823955  0.671
2001 Shepherd TG, Kockeritz L, Szrajber MR, Muller WJ, Hassell JA. The pea3 subfamily ets genes are required for HER2/Neu-mediated mammary oncogenesis. Current Biology : Cb. 11: 1739-48. PMID 11719215 DOI: 10.1016/S0960-9822(01)00536-X  0.653
2001 Shepherd T, Hassell JA. Role of Ets transcription factors in mammary gland development and oncogenesis. Journal of Mammary Gland Biology and Neoplasia. 6: 129-40. PMID 11467448 DOI: 10.1023/A:1009576801226  0.682
2001 Howe LR, Crawford HC, Subbaramaiah K, Hassell JA, Dannenberg AJ, Brown AM. PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2. The Journal of Biological Chemistry. 276: 20108-15. PMID 11274170 DOI: 10.1074/Jbc.M010692200  0.342
2001 Crawford HC, Fingleton B, Gustavson MD, Kurpios N, Wagenaar RA, Hassell JA, Matrisian LM. The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors. Molecular and Cellular Biology. 21: 1370-83. PMID 11158322 DOI: 10.1128/Mcb.21.4.1370-1383.2001  0.377
1998 O'Hagan RC, Hassell JA. The PEA3 Ets transcription factor is a downstream target of the HER2/Neu receptor tyrosine kinase. Oncogene. 16: 301-10. PMID 9467955 DOI: 10.1038/sj.onc.1201547  0.351
1997 Benz CC, O'Hagan RC, Richter B, Scott GK, Chang CH, Xiong X, Chew K, Ljung BM, Edgerton S, Thor A, Hassell JA. HER2/Neu and the Ets transcription activator PEA3 are coordinately upregulated in human breast cancer. Oncogene. 15: 1513-25. PMID 9380403 DOI: 10.1038/sj.onc.1201331  0.447
1992 Xin JH, Cowie A, Lachance P, Hassell JA. Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells. Genes & Development. 6: 481-96. PMID 1547944 DOI: 10.1101/gad.6.3.481  0.335
1989 Martínez-Salas E, Linney E, Hassell J, DePamphilis ML. The need for enhancers in gene expression first appears during mouse development with formation of the zygotic nucleus. Genes & Development. 3: 1493-506. PMID 2558965 DOI: 10.1101/Gad.3.10.1493  0.445
1977 Hassell J, Engelhardt DL. Factors regulating the multiplication of animal cells in culture. Experimental Cell Research. 107: 159-67. PMID 405232 DOI: 10.1016/0014-4827(77)90397-4  0.317
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