| Year |
Citation |
Score |
| 2024 |
Swanton C, Bernard E, Abbosh C, André F, Auwerx J, Balmain A, Bar-Sagi D, Bernards R, Bullman S, DeGregori J, Elliott C, Erez A, Evan G, Febbraio MA, Hidalgo A, ... ... Joyce JA, et al. Embracing cancer complexity: Hallmarks of systemic disease. Cell. 187: 1589-1616. PMID 38552609 DOI: 10.1016/j.cell.2024.02.009 |
0.401 |
|
| 2024 |
Bejarano L, Kauzlaric A, Lamprou E, Lourenco J, Fournier N, Ballabio M, Colotti R, Maas R, Galland S, Massara M, Soukup K, Lilja J, Brouland JP, Hottinger AF, Daniel RT, ... ... Joyce JA, et al. Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms. Cancer Cell. PMID 38242126 DOI: 10.1016/j.ccell.2023.12.018 |
0.371 |
|
| 2023 |
Ben-Chetrit N, Niu X, Sotelo J, Swett AD, Rajasekhar VK, Jiao MS, Stewart CM, Bhardwaj P, Kottapalli S, Ganesan S, Loyher PL, Potenski C, Hannuna A, Brown KA, Iyengar NM, ... ... Joyce JA, et al. Breast Cancer Macrophage Heterogeneity and Self-renewal are Determined by Spatial Localization. Biorxiv : the Preprint Server For Biology. PMID 37961223 DOI: 10.1101/2023.10.24.563749 |
0.443 |
|
| 2023 |
Maas RR, Soukup K, Fournier N, Massara M, Galland S, Kornete M, Wischnewski V, Lourenco J, Croci D, Álvarez-Prado ÁF, Marie DN, Lilja J, Marcone R, Calvo GF, Santalla Mendez R, ... ... Joyce JA, et al. The local microenvironment drives activation of neutrophils in human brain tumors. Cell. PMID 37769657 DOI: 10.1016/j.cell.2023.08.043 |
0.467 |
|
| 2023 |
Wischnewski V, Maas RR, Aruffo PG, Soukup K, Galletti G, Kornete M, Galland S, Fournier N, Lilja J, Wirapati P, Lourenco J, Scarpa A, Daniel RT, Hottinger AF, Brouland JP, ... ... Joyce JA, et al. Phenotypic diversity of T cells in human primary and metastatic brain tumors revealed by multiomic interrogation. Nature Cancer. PMID 37217652 DOI: 10.1038/s43018-023-00566-3 |
0.416 |
|
| 2023 |
de Visser KE, Joyce JA. The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth. Cancer Cell. 41: 374-403. PMID 36917948 DOI: 10.1016/j.ccell.2023.02.016 |
0.502 |
|
| 2023 |
Álvarez-Prado ÁF, Maas RR, Soukup K, Klemm F, Kornete M, Krebs FS, Zoete V, Berezowska S, Brouland JP, Hottinger AF, Daniel RT, Hegi ME, Joyce JA. Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors. Cell Reports. Medicine. 4: 100900. PMID 36652909 DOI: 10.1016/j.xcrm.2022.100900 |
0.374 |
|
| 2022 |
Croci D, Santalla Méndez R, Temme S, Soukup K, Fournier N, Zomer A, Colotti R, Wischnewski V, Flögel U, van Heeswijk RB, Joyce JA. Multispectral fluorine-19 MRI enables longitudinal and noninvasive monitoring of tumor-associated macrophages. Science Translational Medicine. 14: eabo2952. PMID 36260692 DOI: 10.1126/scitranslmed.abo2952 |
0.408 |
|
| 2022 |
Chryplewicz A, Scotton J, Tichet M, Zomer A, Shchors K, Joyce JA, Homicsko K, Hanahan D. Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity. Cancer Cell. PMID 36113478 DOI: 10.1016/j.ccell.2022.08.014 |
0.477 |
|
| 2022 |
Zomer A, Croci D, Kowal J, van Gurp L, Joyce JA. Multimodal imaging of the dynamic brain tumor microenvironment during glioblastoma progression and in response to treatment. Iscience. 25: 104570. PMID 35769877 DOI: 10.1016/j.isci.2022.104570 |
0.46 |
|
| 2021 |
Klemm F, Möckl A, Salamero-Boix A, Alekseeva T, Schäffer A, Schulz M, Niesel K, Maas RR, Groth M, Elie BT, Bowman RL, Hegi ME, Daniel RT, Zeiner PS, Zinke J, ... ... Joyce JA, et al. Compensatory CSF2-driven macrophage activation promotes adaptive resistance to CSF1R inhibition in breast-to-brain metastasis. Nature Cancer. 2: 1086-1101. PMID 35121879 DOI: 10.1038/s43018-021-00254-0 |
0.463 |
|
| 2021 |
Maas RR, Soukup K, Klemm F, Kornete M, Bowman RL, Bedel R, Marie DN, Álvarez-Prado ÁF, Labes D, Wilson A, Brouland JP, Daniel RT, Hegi ME, Joyce JA. An integrated pipeline for comprehensive analysis of immune cells in human brain tumor clinical samples. Nature Protocols. PMID 34462595 DOI: 10.1038/s41596-021-00594-2 |
0.359 |
|
| 2021 |
Bejarano L, Jordāo MJC, Joyce JA. Therapeutic Targeting of the Tumor Microenvironment. Cancer Discovery. 11: 933-959. PMID 33811125 DOI: 10.1158/2159-8290.CD-20-1808 |
0.323 |
|
| 2020 |
Akkari L, Bowman RL, Tessier J, Klemm F, Handgraaf SM, de Groot M, Quail DF, Tillard L, Gadiot J, Huse JT, Brandsma D, Westerga J, Watts C, Joyce JA. Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance. Science Translational Medicine. 12. PMID 32669424 DOI: 10.1126/Scitranslmed.Aaw7843 |
0.701 |
|
| 2020 |
Dumas AA, Pomella N, Rosser G, Guglielmi L, Vinel C, Millner TO, Rees J, Aley N, Sheer D, Wei J, Marisetty A, Heimberger AB, Bowman RL, Brandner S, Joyce JA, et al. Microglia promote glioblastoma via mTOR-mediated immunosuppression of the tumour microenvironment. The Embo Journal. e103790. PMID 32567735 DOI: 10.15252/Embj.2019103790 |
0.317 |
|
| 2020 |
Klemm F, Maas RR, Bowman RL, Kornete M, Soukup K, Nassiri S, Brouland JP, Iacobuzio-Donahue CA, Brennan C, Tabar V, Gutin PH, Daniel RT, Hegi ME, Joyce JA. Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells. Cell. PMID 32470396 DOI: 10.1016/J.Cell.2020.05.007 |
0.404 |
|
| 2019 |
Kowal J, Kornete M, Joyce JA. Re-education of macrophages as a therapeutic strategy in cancer. Immunotherapy. 11: 677-689. PMID 31088236 DOI: 10.2217/imt-2018-0156 |
0.355 |
|
| 2018 |
Soukup K, Joyce JA. A Long-Distance Relay-tionship between Tumor and Bone. Immunity. 48: 13-16. PMID 29343434 DOI: 10.1016/j.immuni.2017.12.011 |
0.387 |
|
| 2017 |
Olson OC, Quail DF, Joyce JA. Obesity and the tumor microenvironment. Science (New York, N.Y.). 358: 1130-1131. PMID 29191893 DOI: 10.1126/Science.Aao5801 |
0.667 |
|
| 2017 |
Bakst RL, Xiong H, Chen CH, Deborde S, Lyubchik A, Zhou Y, He S, McNamara WF, Lee SY, Olson OC, Leiner I, Marcadis AR, Keith JW, Al-Ahmadie HA, Katabi N, ... ... Joyce JA, et al. Inflammatory monocytes promote perineural invasion via CCL2-mediated recruitment and cathepsin B expression. Cancer Research. PMID 28951461 DOI: 10.1158/0008-5472.Can-17-1612 |
0.307 |
|
| 2017 |
Yan D, Kowal J, Akkari L, Schuhmacher AJ, Huse JT, West BL, Joyce JA. Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas. Oncogene. PMID 28759044 DOI: 10.1038/Onc.2017.261 |
0.435 |
|
| 2017 |
Quail DF, Olson OC, Bhardwaj P, Walsh LA, Akkari L, Quick ML, Chen IC, Wendel N, Ben-Chetrit N, Walker J, Holt PR, Dannenberg AJ, Joyce JA. Obesity alters the lung myeloid cell landscape to enhance breast cancer metastasis through IL5 and GM-CSF. Nature Cell Biology. PMID 28737771 DOI: 10.1038/Ncb3578 |
0.653 |
|
| 2017 |
Olson OC, Kim H, Quail DF, Foley EA, Joyce JA. Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents. Cell Reports. 19: 101-113. PMID 28380350 DOI: 10.1016/J.Celrep.2017.03.038 |
0.737 |
|
| 2017 |
Quail DF, Joyce JA. The Microenvironmental Landscape of Brain Tumors. Cancer Cell. 31: 326-341. PMID 28292436 DOI: 10.1016/J.Ccell.2017.02.009 |
0.692 |
|
| 2017 |
Carmona-Fontaine C, Deforet M, Akkari L, Thompson CB, Joyce JA, Xavier JB. Metabolic origins of spatial organization in the tumor microenvironment. Proceedings of the National Academy of Sciences of the United States of America. PMID 28246332 DOI: 10.1073/Pnas.1700600114 |
0.46 |
|
| 2016 |
Quail DF, Joyce JA. Molecular Pathways: Deciphering Mechanisms of Resistance to Macrophage-Targeted Therapies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27895033 DOI: 10.1158/1078-0432.Ccr-16-0133 |
0.72 |
|
| 2016 |
Bowman RL, Klemm F, Akkari L, Pyonteck SM, Sevenich L, Quail DF, Dhara S, Simpson K, Gardner EE, Iacobuzio-Donahue CA, Brennan CW, Tabar V, Gutin PH, Joyce JA. Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies. Cell Reports. PMID 27840052 DOI: 10.1016/J.Celrep.2016.10.052 |
0.793 |
|
| 2016 |
Yan D, Wang HW, Bowman RL, Joyce JA. STAT3 and STAT6 Signaling Pathways Synergize to Promote Cathepsin Secretion from Macrophages via IRE1α Activation. Cell Reports. 16: 2914-2927. PMID 27626662 DOI: 10.1016/J.Celrep.2016.08.035 |
0.724 |
|
| 2016 |
Edgington-Mitchell LE, Wartmann T, Fleming AK, Gocheva V, van der Linden WA, Withana NP, Verdoes M, Aurelio L, Edgington-Mitchell D, Lieu T, Parker BS, Graham B, Reinheckel T, Furness JB, Joyce JA, et al. Legumain is Activated in Macrophages during Pancreatitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00047.2016. PMID 27514475 DOI: 10.1152/Ajpgi.00047.2016 |
0.729 |
|
| 2016 |
Prudova A, Gocheva V, Auf dem Keller U, Eckhard U, Olson OC, Akkari L, Butler GS, Fortelny N, Lange PF, Mark JC, Joyce JA, Overall CM. TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors. Cell Reports. PMID 27477282 DOI: 10.1016/J.Celrep.2016.06.086 |
0.735 |
|
| 2016 |
Akkari L, Joyce JA. Microenvironmental InterFereNce of metabolism regulates chemosensitivity. Cell Research. PMID 27349476 DOI: 10.1038/cr.2016.82 |
0.357 |
|
| 2016 |
Quail DF, Bowman RL, Akkari L, Quick ML, Schuhmacher AJ, Huse JT, Holland EC, Sutton JC, Joyce JA. The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas. Science (New York, N.Y.). 352. PMID 27199435 DOI: 10.1126/Science.Aad3018 |
0.71 |
|
| 2016 |
Akkari L, Gocheva V, Quick ML, Kester JC, Spencer AK, Garfall AL, Bowman RL, Joyce JA. Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer. Genes & Development. 30: 220-32. PMID 26773004 DOI: 10.1101/Gad.270439.115 |
0.798 |
|
| 2015 |
Olson OC, Joyce JA. Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response. Nature Reviews. Cancer. 15: 712-29. PMID 26597527 DOI: 10.1038/nrc4027 |
0.331 |
|
| 2015 |
Hughes R, Qian BZ, Rowan C, Muthana M, Keklikoglou I, Olson OC, Tazzyman S, Danson S, Addison C, Clemons M, Gonzalez-Angulo AM, Joyce JA, De Palma M, Pollard JW, Lewis CE. Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy. Cancer Research. 75: 3479-91. PMID 26269531 DOI: 10.1158/0008-5472.Can-14-3587 |
0.44 |
|
| 2015 |
Sobotič B, Vizovišek M, Vidmar R, Van Damme P, Gocheva V, Joyce JA, Gevaert K, Turk V, Turk B, Fonović M. Proteomic Identification of Cysteine Cathepsin Substrates Shed from the Surface of Cancer Cells. Molecular & Cellular Proteomics : McP. 14: 2213-28. PMID 26081835 DOI: 10.1074/Mcp.M114.044628 |
0.733 |
|
| 2015 |
Brindle NR, Joyce JA, Rostker F, Lawlor ER, Swigart-Brown L, Evan G, Hanahan D, Shchors K. Deficiency for the cysteine protease cathepsin L impairs Myc-induced tumorigenesis in a mouse model of pancreatic neuroendocrine cancer. Plos One. 10: e0120348. PMID 25927437 DOI: 10.1371/Journal.Pone.0120348 |
0.381 |
|
| 2015 |
Joyce JA, Fearon DT. T cell exclusion, immune privilege, and the tumor microenvironment. Science (New York, N.Y.). 348: 74-80. PMID 25838376 DOI: 10.1126/science.aaa6204 |
0.321 |
|
| 2015 |
Klemm F, Joyce JA. Microenvironmental regulation of therapeutic response in cancer. Trends in Cell Biology. 25: 198-213. PMID 25540894 DOI: 10.1016/j.tcb.2014.11.006 |
0.401 |
|
| 2014 |
Sevenich L, Joyce JA. Pericellular proteolysis in cancer. Genes & Development. 28: 2331-47. PMID 25367033 DOI: 10.1101/gad.250647.114 |
0.41 |
|
| 2014 |
Akkari L, Gocheva V, Kester JC, Hunter KE, Quick ML, Sevenich L, Wang HW, Peters C, Tang LH, Klimstra DS, Reinheckel T, Joyce JA. Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix. Genes & Development. 28: 2134-50. PMID 25274726 DOI: 10.1101/Gad.249599.114 |
0.843 |
|
| 2014 |
Sevenich L, Bowman RL, Mason SD, Quail DF, Rapaport F, Elie BT, Brogi E, Brastianos PK, Hahn WC, Holsinger LJ, Massagué J, Leslie CS, Joyce JA. Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S. Nature Cell Biology. 16: 876-88. PMID 25086747 DOI: 10.1038/Ncb3011 |
0.685 |
|
| 2014 |
Bowman RL, Joyce JA. Therapeutic targeting of tumor-associated macrophages and microglia in glioblastoma. Immunotherapy. 6: 663-6. PMID 25041027 DOI: 10.2217/imt.14.48 |
0.412 |
|
| 2014 |
Alonso-Curbelo D, Riveiro-Falkenbach E, Pérez-Guijarro E, Cifdaloz M, Karras P, Osterloh L, Megías D, Cañón E, Calvo TG, Olmeda D, Gómez-López G, Graña O, Sánchez-Arévalo Lobo VJ, Pisano DG, Wang HW, ... ... Joyce JA, et al. RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway. Cancer Cell. 26: 61-76. PMID 24981740 DOI: 10.1016/J.Ccr.2014.04.030 |
0.72 |
|
| 2014 |
Hunter KE, Palermo C, Kester JC, Simpson K, Li JP, Tang LH, Klimstra DS, Vlodavsky I, Joyce JA. Heparanase promotes lymphangiogenesis and tumor invasion in pancreatic neuroendocrine tumors Oncogene. 33: 1799-1808. PMID 23644656 DOI: 10.1038/onc.2013.142 |
0.535 |
|
| 2014 |
Quail DF, Joyce JA. Inflammation and Cancer The Molecular Basis of Cancer: Fourth Edition. 285-296.e3. DOI: 10.1016/B978-1-4557-4066-6.00019-6 |
0.664 |
|
| 2013 |
Carmona-Fontaine C, Bucci V, Akkari L, Deforet M, Joyce JA, Xavier JB. Emergence of spatial structure in the tumor microenvironment due to the Warburg effect. Proceedings of the National Academy of Sciences of the United States of America. 110: 19402-7. PMID 24218566 DOI: 10.1073/Pnas.1311939110 |
0.477 |
|
| 2013 |
Quail DF, Joyce JA. Microenvironmental regulation of tumor progression and metastasis. Nature Medicine. 19: 1423-37. PMID 24202395 DOI: 10.1038/Nm.3394 |
0.773 |
|
| 2013 |
Pyonteck SM, Akkari L, Schuhmacher AJ, Bowman RL, Sevenich L, Quail DF, Olson OC, Quick ML, Huse JT, Teijeiro V, Setty M, Leslie CS, Oei Y, Pedraza A, Zhang J, ... ... Joyce JA, et al. CSF-1R inhibition alters macrophage polarization and blocks glioma progression. Nature Medicine. 19: 1264-72. PMID 24056773 DOI: 10.1038/Nm.3337 |
0.781 |
|
| 2013 |
Hunter KE, Quick ML, Sadanandam A, Hanahan D, Joyce JA. Identification and characterization of poorly differentiated invasive carcinomas in a mouse model of pancreatic neuroendocrine tumorigenesis. Plos One. 8: e64472. PMID 23691228 DOI: 10.1371/Journal.Pone.0064472 |
0.39 |
|
| 2013 |
Lujambio A, Akkari L, Simon J, Grace D, Tschaharganeh DF, Bolden JE, Zhao Z, Thapar V, Joyce JA, Krizhanovsky V, Lowe SW. Non-cell-autonomous tumor suppression by p53. Cell. 153: 449-60. PMID 23562644 DOI: 10.1016/J.Cell.2013.03.020 |
0.35 |
|
| 2013 |
Ryder M, Gild M, Hohl TM, Pamer E, Knauf J, Ghossein R, Joyce JA, Fagin JA. Genetic and pharmacological targeting of CSF-1/CSF-1R inhibits tumor-associated macrophages and impairs BRAF-induced thyroid cancer progression. Plos One. 8: e54302. PMID 23372702 DOI: 10.1371/Journal.Pone.0054302 |
0.394 |
|
| 2013 |
Jacobson LS, Lima H, Goldberg MF, Gocheva V, Tsiperson V, Sutterwala FS, Joyce JA, Gapp BV, Blomen VA, Chandran K, Brummelkamp TR, Diaz-Griffero F, Brojatsch J. Cathepsin-mediated necrosis controls the adaptive immune response by Th2 (T helper type 2)-associated adjuvants. The Journal of Biological Chemistry. 288: 7481-91. PMID 23297415 DOI: 10.1074/Jbc.M112.400655 |
0.704 |
|
| 2012 |
Pyonteck SM, Gadea BB, Wang HW, Gocheva V, Hunter KE, Tang LH, Joyce JA. Deficiency of the macrophage growth factor CSF-1 disrupts pancreatic neuroendocrine tumor development. Oncogene. 31: 1459-67. PMID 21822305 DOI: 10.1038/onc.2011.337 |
0.793 |
|
| 2011 |
Shree T, Olson OC, Elie BT, Kester JC, Garfall AL, Simpson K, Bell-McGuinn KM, Zabor EC, Brogi E, Joyce JA. Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer. Genes & Development. 25: 2465-79. PMID 22156207 DOI: 10.1101/Gad.180331.111 |
0.806 |
|
| 2011 |
Mason SD, Joyce JA. Proteolytic networks in cancer. Trends in Cell Biology. 21: 228-37. PMID 21232958 DOI: 10.1016/j.tcb.2010.12.002 |
0.404 |
|
| 2011 |
Sevenich L, Mason S, Rapaport F, Massague J, Leslie C, Joyce J. Abstract 2844: Systems biology analysis of tumor and stromal genes in different metastatic microenvironments Cancer Research. 71: 2844-2844. DOI: 10.1158/1538-7445.Am2011-2844 |
0.586 |
|
| 2010 |
Wang HW, Joyce JA. Alternative activation of tumor-associated macrophages by IL-4: priming for protumoral functions. Cell Cycle (Georgetown, Tex.). 9: 4824-35. PMID 21150330 DOI: 10.4161/Cc.9.24.14322 |
0.701 |
|
| 2010 |
Gocheva V, Chen X, Peters C, Reinheckel T, Joyce JA. Deletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancer. Biological Chemistry. 391: 937-45. PMID 20731543 DOI: 10.1515/Bc.2010.080 |
0.793 |
|
| 2010 |
Elie BT, Gocheva V, Shree T, Dalrymple SA, Holsinger LJ, Joyce JA. Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model. Biochimie. 92: 1618-24. PMID 20447439 DOI: 10.1016/J.Biochi.2010.04.023 |
0.821 |
|
| 2010 |
Gocheva V, Wang HW, Gadea BB, Shree T, Hunter KE, Garfall AL, Berman T, Joyce JA. IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion. Genes & Development. 24: 241-55. PMID 20080943 DOI: 10.1101/Gad.1874010 |
0.822 |
|
| 2009 |
Amankulor NM, Hambardzumyan D, Pyonteck SM, Becher OJ, Joyce JA, Holland EC. Sonic hedgehog pathway activation is induced by acute brain injury and regulated by injury-related inflammation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10299-308. PMID 19692604 DOI: 10.1523/Jneurosci.2500-09.2009 |
0.75 |
|
| 2009 |
Chang SH, Kanasaki K, Gocheva V, Blum G, Harper J, Moses MA, Shih SC, Nagy JA, Joyce J, Bogyo M, Kalluri R, Dvorak HF. VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation. Cancer Research. 69: 4537-44. PMID 19435903 DOI: 10.1158/0008-5472.Can-08-4539 |
0.734 |
|
| 2009 |
Joyce JA, Pollard JW. Microenvironmental regulation of metastasis. Nature Reviews. Cancer. 9: 239-52. PMID 19279573 DOI: 10.1038/Nrc2618 |
0.306 |
|
| 2008 |
Palermo C, Joyce JA. Cysteine cathepsin proteases as pharmacological targets in cancer. Trends in Pharmacological Sciences. 29: 22-8. PMID 18037508 DOI: 10.1016/j.tips.2007.10.011 |
0.351 |
|
| 2008 |
Reinheckel T, Gocheva V, Peters C, Joyce JA. Roles of cysteine proteases in tumor progression: Analysis of cysteine cathepsin knockout mice in cancer models The Cancer Degradome: Proteases and Cancer Biology. 281-304. DOI: 10.1007/978-0-387-69057-5_15 |
0.785 |
|
| 2007 |
Bell-McGuinn KM, Garfall AL, Bogyo M, Hanahan D, Joyce JA. Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer. Cancer Research. 67: 7378-85. PMID 17671208 DOI: 10.1158/0008-5472.Can-07-0602 |
0.434 |
|
| 2007 |
Sadaghiani AM, Verhelst SH, Gocheva V, Hill K, Majerova E, Stinson S, Joyce JA, Bogyo M. Design, synthesis, and evaluation of in vivo potency and selectivity of epoxysuccinyl-based inhibitors of papain-family cysteine proteases. Chemistry & Biology. 14: 499-511. PMID 17524981 DOI: 10.1016/J.Chembiol.2007.03.010 |
0.694 |
|
| 2007 |
Gocheva V, Joyce JA. Cysteine cathepsins and the cutting edge of cancer invasion. Cell Cycle (Georgetown, Tex.). 6: 60-4. PMID 17245112 DOI: 10.4161/Cc.6.1.3669 |
0.794 |
|
| 2006 |
Gadea BB, Joyce JA. Tumour-host interactions: implications for developing anti-cancer therapies. Expert Reviews in Molecular Medicine. 8: 1-32. PMID 17156575 DOI: 10.1017/S1462399406000172 |
0.308 |
|
| 2006 |
Gocheva V, Zeng W, Ke D, Klimstra D, Reinheckel T, Peters C, Hanahan D, Joyce JA. Distinct roles for cysteine cathepsin genes in multistage tumorigenesis. Genes & Development. 20: 543-56. PMID 16481467 DOI: 10.1101/Gad.1407406 |
0.795 |
|
| 2006 |
Gocheva V, Zeng W, Ke D, Klimstra D, Reinheckel T, Peters C, Hanahan D, Joyce J. ID: 356 Distinct roles for cysteine cathepsins in multistage tumorigenesis Journal of Thrombosis and Haemostasis. 4: 41-41. DOI: 10.1111/j.1538-7836.2006.00356.x |
0.703 |
|
| 2005 |
Joyce JA. Therapeutic targeting of the tumor microenvironment. Cancer Cell. 7: 513-20. PMID 15950901 DOI: 10.1016/j.ccr.2005.05.024 |
0.384 |
|
| 2005 |
Joyce JA, Freeman C, Meyer-Morse N, Parish CR, Hanahan D. A functional heparan sulfate mimetic implicates both heparanase and heparan sulfate in tumor angiogenesis and invasion in a mouse model of multistage cancer. Oncogene. 24: 4037-51. PMID 15806157 DOI: 10.1038/Sj.Onc.1208602 |
0.398 |
|
| 2004 |
Joyce JA, Hanahan D. Multiple roles for cysteine cathepsins in cancer. Cell Cycle (Georgetown, Tex.). 3: 1516-619. PMID 15539953 |
0.48 |
|
| 2004 |
Joyce JA, Baruch A, Chehade K, Meyer-Morse N, Giraudo E, Tsai FY, Greenbaum DC, Hager JH, Bogyo M, Hanahan D. Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis. Cancer Cell. 5: 443-53. PMID 15144952 DOI: 10.1016/S1535-6108(04)00111-4 |
0.44 |
|
| 2003 |
Joyce JA, Laakkonen P, Bernasconi M, Bergers G, Ruoslahti E, Hanahan D. Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis. Cancer Cell. 4: 393-403. PMID 14667506 DOI: 10.1016/S1535-6108(03)00271-X |
0.348 |
|
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