Todd M. Brusko, Ph.D. - Publications

Affiliations: 
2006 University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Immunology, Cell Biology

140 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Herold KC, Delong T, Perdigoto AL, Biru N, Brusko TM, Walker LSK. The immunology of type 1 diabetes. Nature Reviews. Immunology. PMID 38308004 DOI: 10.1038/s41577-023-00985-4  0.367
2023 Foster TP, Jacobsen LM, Bruggeman B, Salmon C, Hosford J, Chen A, Cintron M, Mathews CE, Wasserfall C, Brusko MA, Brusko TM, Atkinson MA, Schatz DA, Haller MJ. Low-Dose Antithymocyte Globulin: A Pragmatic Approach to Treating Stage 2 Type 1 Diabetes. Diabetes Care. PMID 38117469 DOI: 10.2337/dc23-1750  0.417
2023 Chen J, Liu C, Chernatynskaya AV, Newby B, Brusko TM, Xu Y, Barra JM, Morgan N, Santarlas C, Reeves WH, Tse HM, Leiding JW, Mathews CE. NADPH Oxidase 2-Derived Reactive Oxygen Species Promote CD8+ T Cell Effector Function. Journal of Immunology (Baltimore, Md. : 1950). PMID 38079221 DOI: 10.4049/jimmunol.2200691  0.365
2023 Redondo MJ, Harrall KK, Glueck DH, Tosur M, Uysal S, Muir A, Atkinson EG, Shapiro MR, Yu L, Winter WE, Weedon M, Brusko TM, Oram R, Vehik K, Hagopian W, et al. Diabetes Study of Children of Diverse Ethnicity and Race: Study design. Diabetes/Metabolism Research and Reviews. e3744. PMID 37888801 DOI: 10.1002/dmrr.3744  0.454
2023 Thirawatananond P, Brown ME, Sachs LK, Arnoletti JM, Yeh WI, Posgai AL, Shapiro MR, Chen YG, Brusko TM. Treg-specific CD226 Deletion Reduces Diabetes Incidence in NOD Mice by Improving Regulatory T Cell Stability. Diabetes. PMID 37625150 DOI: 10.2337/db23-0307  0.406
2023 Shapiro MR, Dong X, Perry DJ, McNichols JM, Thirawatananond P, Posgai AL, Peters LD, Motwani K, Musca RS, Muir A, Concannon P, Jacobsen LM, Mathews CE, Wasserfall CH, Haller MJ, ... ... Brusko TM, et al. Human immune phenotyping reveals accelerated aging in type 1 diabetes. Jci Insight. PMID 37498686 DOI: 10.1172/jci.insight.170767  0.478
2023 Matsumoto R, Gray J, Rybkina K, Oppenheimer H, Levy L, Friedman LM, Khamaisi M, Meng W, Rosenfeld AM, Guyer RS, Bradley MC, Chen D, Atkinson MA, Brusko TM, Brusko M, et al. Induction of bronchus-associated lymphoid tissue is an early life adaptation for promoting human B cell immunity. Nature Immunology. PMID 37460638 DOI: 10.1038/s41590-023-01557-3  0.415
2023 Jacobsen LM, Diggins K, Blanchfield L, McNichols JA, Perry DJ, Brant J, Dong X, Bacher R, Gersuk VH, Schatz DA, Atkinson MA, Mathews CE, Haller MJ, Long SA, Linsley PS, ... Brusko TM, et al. Responders to low-dose ATG induce CD4 T cell exhaustion in type 1 diabetes. Jci Insight. PMID 37432736 DOI: 10.1172/jci.insight.161812  0.55
2023 Connors TJ, Matsumoto R, Verma S, Szabo PA, Guyer R, Gray J, Wang Z, Thapa P, Dogra P, Poon MML, Rybkina K, Bradley MC, Idzikowski E, McNichols J, Kubota M, ... ... Brusko TM, et al. Site-specific development and progressive maturation of human tissue-resident memory T cells over infancy and childhood. Immunity. PMID 37421943 DOI: 10.1016/j.immuni.2023.06.008  0.444
2023 Peters LD, Yeh WI, Arnoletti JM, Brown ME, Posgai AL, Mathews CE, Brusko TM. Modeling cell-mediated immunity in human type 1 diabetes by engineering autoreactive CD8 T cells. Frontiers in Immunology. 14: 1142648. PMID 37325626 DOI: 10.3389/fimmu.2023.1142648  0.44
2023 Becker MW, Peters LD, Myint T, Smurlick D, Powell A, Brusko TM, Phelps EA. Immune engineered extracellular vesicles to modulate T cell activation in the context of type 1 diabetes. Science Advances. 9: eadg1082. PMID 37267353 DOI: 10.1126/sciadv.adg1082  0.401
2023 Perry DJ, Shapiro MR, Chamberlain SW, Kusmartseva I, Chamala S, Balzano-Nogueira L, Yang M, Brant JO, Brusko M, Williams MD, McGrail KM, McNichols J, Peters LD, Posgai AL, Kaddis JS, ... ... Brusko TM, et al. A genomic data archive from the Network for Pancreatic Organ donors with Diabetes. Scientific Data. 10: 323. PMID 37237059 DOI: 10.1038/s41597-023-02244-6  0.47
2022 Redondo MJ, Richardson SJ, Perry D, Minard CG, Carr ALJ, Brusko T, Kusmartseva I, Pugliese A, Atkinson MA. Milder loss of insulin-containing islets in individuals with type 1 diabetes and type 2 diabetes-associated TCF7L2 genetic variants. Diabetologia. PMID 36282337 DOI: 10.1007/s00125-022-05818-y  0.484
2022 Marshall GP, Cserny J, Wang CW, Looney B, Posgai AL, Bacher R, Keselowsky B, Brusko TM. Biomaterials-based nanoparticles conjugated to regulatory T cells provide a modular system for localized delivery of pharmacotherapeutic agents. Journal of Biomedical Materials Research. Part A. PMID 36082558 DOI: 10.1002/jbm.a.37442  0.304
2022 Brown ME, Peters LD, Hanbali SR, Arnoletti JM, Sachs LK, Nguyen KQ, Carpenter EB, Seay HR, Fuhrman CA, Posgai AL, Shapiro MR, Brusko TM. Human CD4CD25CD226 Tregs Demonstrate Increased Purity, Lineage Stability, and Suppressive Capacity Versus CD4CD25CD127 Tregs for Adoptive Cell Therapy. Frontiers in Immunology. 13: 873560. PMID 35693814 DOI: 10.3389/fimmu.2022.873560  0.376
2022 Kaddis JS, Perry DJ, Vu AN, Rich SS, Atkinson MA, Schatz DA, Roep BO, Brusko TM. Improving the Prediction of Type 1 Diabetes Across Ancestries. Diabetes Care. PMID 35043156 DOI: 10.2337/dc21-1254  0.447
2022 Yang JHM, Ward-Hartstonge KA, Perry DJ, Blanchfield JL, Posgai AL, Wiedeman AE, Diggins K, Rahman A, Tree TIM, Brusko TM, Levings MK, James EA, Kent SC, Speake C, Homann D, et al. Guidelines for standardizing T-cell cytometry assays to link biomarkers, mechanisms, and disease outcomes in type 1 diabetes. European Journal of Immunology. 52: 372-388. PMID 35025103 DOI: 10.1002/eji.202049067  0.333
2021 Missarova A, Jain J, Butler A, Ghazanfar S, Stuart T, Brusko M, Wasserfall C, Nick H, Brusko T, Atkinson M, Satija R, Marioni JC. geneBasis: an iterative approach for unsupervised selection of targeted gene panels from scRNA-seq. Genome Biology. 22: 333. PMID 34872616 DOI: 10.1186/s13059-021-02548-z  0.38
2021 Armitage LH, Stimpson SE, Santostefano KE, Sui L, Ogundare S, Newby BN, Castro-Gutierrez R, Huber MK, Taylor JP, Sharma P, Radichev IA, Perry DJ, Fredette NC, Savinov AY, Wallet MA, ... ... Brusko TM, et al. Use of Induced Pluripotent Stem Cells to Build Isogenic Systems and Investigate Type 1 Diabetes. Frontiers in Endocrinology. 12: 737276. PMID 34858326 DOI: 10.3389/fendo.2021.737276  0.344
2021 Linsley PS, Barahmand-Pour-Whitman F, Balmas E, DeBerg HA, Flynn KJ, Hu AK, Rosasco MG, Chen J, O'Rourke C, Serti E, Gersuk VH, Motwani K, Seay HR, Brusko TM, Kwok WW, et al. Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes. Jci Insight. 6. PMID 34806648 DOI: 10.1172/jci.insight.151349  0.38
2021 Brusko TM, Mallone R, Rodriguez-Calvo T. Editorial: Footprints of Immune Cells in the Type 1 Diabetic Pancreas. Frontiers in Endocrinology. 12: 767012. PMID 34721308 DOI: 10.3389/fendo.2021.767012  0.339
2021 Vecchione A, Jofra T, Gerosa J, Shankwitz K, Di Fonte R, Galvani G, Ippolito E, Cicalese MP, Schultz AR, Seay HR, Favellato M, Milardi G, Stabilini A, Ragogna F, Grogan P, ... ... Brusko T, et al. Reduced Follicular Regulatory T Cells in Spleen and Pancreatic Lymph Nodes of Patients With Type 1 Diabetes. Diabetes. 70: 2892-2902. PMID 34620616 DOI: 10.2337/db21-0091  0.355
2021 Sharp RC, Brown ME, Shapiro MR, Posgai AL, Brusko TM. The Immunoregulatory Role of the Signal Regulatory Protein Family and CD47 Signaling Pathway in Type 1 Diabetes. Frontiers in Immunology. 12: 739048. PMID 34603322 DOI: 10.3389/fimmu.2021.739048  0.305
2021 Brusko TM, Russ HA, Stabler CL. Strategies for durable β cell replacement in type 1 diabetes. Science (New York, N.Y.). 373: 516-522. PMID 34326233 DOI: 10.1126/science.abh1657  0.305
2021 Perry DJ, Peters LD, Lakshmi PS, Zhang L, Han Z, Wasserfall CH, Mathews CE, Atkinson MA, Brusko TM. Overexpression of the Autoimmune Risk Variant LYP-620W Fails to Restrain Human CD4 T Cell Activation. Journal of Immunology (Baltimore, Md. : 1950). PMID 34301848 DOI: 10.4049/jimmunol.2000708  0.569
2021 Li W, Gong M, Park YP, Elshikha AS, Choi SC, Brown J, Kanda N, Yeh WI, Peters L, Titov AA, Teng X, Brusko TM, Morel L. Lupus susceptibility gene Esrrg modulates regulatory T cells through mitochondrial metabolism. Jci Insight. PMID 34156979 DOI: 10.1172/jci.insight.143540  0.346
2021 Rana J, Perry DJ, Kumar SR, Muñoz-Melero M, Saboungi R, Brusko TM, Biswas M. CAR and TRuC redirected regulatory T cells differ in capacity to control adaptive immunity to FVIII. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33940160 DOI: 10.1016/j.ymthe.2021.04.034  0.324
2021 Lin A, Mack JA, Bruggeman B, Jacobsen LM, Posgai AL, Wasserfall CH, Brusko TM, Atkinson MA, Gitelman SE, Gottlieb PA, Gurka MJ, Mathews CE, Schatz DA, Haller MJ. Low-dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report. Diabetes. PMID 33632742 DOI: 10.2337/db20-1103  0.444
2021 Japp AS, Meng W, Rosenfeld AM, Perry DJ, Thirawatananond P, Bacher RL, Liu C, Gardner JS, Atkinson MA, Kaestner KH, Brusko TM, Naji A, Luning Prak ET, Betts MR. TCR/BCR dual-expressing cells and their associated public BCR clonotype are not enriched in type 1 diabetes. Cell. 184: 827-839.e14. PMID 33545036 DOI: 10.1016/j.cell.2020.11.035  0.485
2021 Ross JJ, Wasserfall CH, Bacher R, Perry DJ, McGrail K, Posgai AL, Dong X, Muir A, Li X, Campbell-Thompson M, Brusko TM, Schatz DA, Haller MJ, Atkinson MA. Exocrine Pancreatic Enzymes Are a Serological Biomarker for Type 1 Diabetes Staging and Pancreas Size. Diabetes. PMID 33441381 DOI: 10.2337/db20-0995  0.474
2021 Williams MD, Bacher R, Perry DJ, Grace CR, McGrail KM, Posgai AL, Muir A, Chamala S, Haller MJ, Schatz DA, Brusko TM, Atkinson MA, Wasserfall CH. Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis. Diabetes. PMID 33419759 DOI: 10.2337/db20-0937  0.468
2020 Walker AF, Atkinson MA, Lee AM, Aulisio G, Brusko TM, Haller MJ, Schatz DA. Teaching Type 1 Diabetes: Creating Stakeholder Engagement in Biomedical Careers Through Undergraduate Research Curriculum. Medical Science Educator. 30: 69-73. PMID 34457640 DOI: 10.1007/s40670-019-00877-0  0.379
2020 Brusko MA, Stewart JM, Posgai AL, Wasserfall CH, Atkinson MA, Brusko TM, Keselowsky BG. Immunomodulatory Dual-Sized Microparticle System Conditions Human Antigen Presenting Cells Into a Tolerogenic Phenotype and Inhibits Type 1 Diabetes-Specific Autoreactive T Cell Responses. Frontiers in Immunology. 11: 574447. PMID 33193362 DOI: 10.3389/fimmu.2020.574447  0.549
2020 Shapiro MR, Yeh WI, Longfield JR, Gallagher J, Infante CM, Wellford S, Posgai AL, Atkinson MA, Campbell-Thompson M, Lieberman SM, Serreze DV, Geurts AM, Chen YG, Brusko TM. CD226 Deletion Reduces Type 1 Diabetes in the NOD Mouse by Impairing Thymocyte Development and Peripheral T Cell Activation. Frontiers in Immunology. 11: 2180. PMID 33013915 DOI: 10.3389/Fimmu.2020.02180  0.624
2020 Ye C, Low BE, Wiles MV, Brusko TM, Serreze DV, Driver JP. CD70 Inversely Regulates Regulatory T Cells and Invariant NKT Cells and Modulates Type 1 Diabetes in NOD Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 32868408 DOI: 10.4049/Jimmunol.2000148  0.451
2020 Jacobsen L, Bundy B, Greco M, Schatz D, Atkinson M, Brusko T, Mathews C, Herold KC, Gitelman S, Krischer J, Haller M. Comparing Beta Cell Preservation Across Clinical Trials in Recent-Onset Type 1 Diabetes. Diabetes Technology & Therapeutics. PMID 32833543 DOI: 10.1089/Dia.2020.0305  0.482
2020 Carr ALJ, Perry DJ, Lynam AL, Chamala S, Flaxman CS, Sharp SA, Ferrat LA, Jones AG, Beery ML, Jacobsen LM, Wasserfall CH, Campbell-Thompson ML, Kusmartseva I, Posgai A, Schatz DA, ... ... Brusko TM, et al. Histological validation of a type 1 diabetes clinical diagnostic model for classification of diabetes. Diabetic Medicine : a Journal of the British Diabetic Association. PMID 32634859 DOI: 10.1111/Dme.14361  0.521
2020 Motwani K, Peters LD, Vliegen WH, El-Sayed AG, Seay HR, Lopez MC, Baker HV, Posgai AL, Brusko MA, Perry DJ, Bacher R, Larkin J, Haller MJ, Brusko TM. Human Regulatory T Cells From Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability Relative to Adult Peripheral Blood. Frontiers in Immunology. 11: 611. PMID 32351504 DOI: 10.3389/Fimmu.2020.00611  0.464
2020 Nelson AS, Maddaloni M, Abbott JR, Hoffman C, Akgul A, Ohland C, Gharaibeh RZ, Jobin C, Brusko TM, Pascual DW. Oral therapy with colonization factor antigen I prevents development of type 1 diabetes in Non-obese Diabetic mice. Scientific Reports. 10: 6156. PMID 32273533 DOI: 10.1038/S41598-020-62881-4  0.487
2020 Ihantola EL, Ilmonen H, Kailaanmäki A, Rytkönen-Nissinen M, Azam A, Maillère B, Lindestam Arlehamn CS, Sette A, Motwani K, Seay HR, Brusko TM, Knip M, Veijola R, Toppari J, Ilonen J, et al. Characterization of Proinsulin T Cell Epitopes Restricted by Type 1 Diabetes-Associated HLA Class II Molecules. Journal of Immunology (Baltimore, Md. : 1950). PMID 32229538 DOI: 10.4049/Jimmunol.1901079  0.438
2020 Dean JW, Peters LD, Fuhrman CA, Seay HR, Posgai AL, Stimpson SE, Brusko MA, Perry DJ, Yeh WI, Newby BN, Haller MJ, Muir AB, Atkinson MA, Mathews CE, Brusko TM. Innate inflammation drives NK cell activation to impair Treg activity. Journal of Autoimmunity. 102417. PMID 32035746 DOI: 10.1016/J.Jaut.2020.102417  0.573
2020 Beam CA, Wasserfall C, Woodwyk A, Akers M, Rauch H, Blok T, Mason P, Vos D, Perry D, Brusko T, Peakman M, Atkinson M. Synchronization of the Normal Human Peripheral Immune System: A Comprehensive Circadian Systems Immunology Analysis. Scientific Reports. 10: 672. PMID 31959869 DOI: 10.1038/S41598-019-56951-5  0.533
2020 LIN A, PERRY DJ, SCHATZ D, BRUSKO TM, ATKINSON MA, HALLER MJ, MATHEWS CE. 253-OR: Circulating Neutrophil Numbers Increase with Age, but Are Not a Biomarker of T1D Risk Diabetes. 69: 253-OR. DOI: 10.2337/Db20-253-Or  0.416
2020 PETERS LD, POSGAI AL, BRUSKO TM. 1663-P: Gene Editing of the Human T-Cell Receptor Locus Enables Optimized In Vitro Testing of Autoreactive T-Cell Function in Type 1 Diabetes Diabetes. 69: 1663-P. DOI: 10.2337/Db20-1663-P  0.461
2019 Shapiro MR, Wasserfall CH, McGrail SM, Posgai AL, Bacher R, Muir A, Haller MJ, Schatz DA, Wesley JD, von Herrath M, Hagopian WA, Speake C, Atkinson MA, Brusko TM. Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis. Diabetes. PMID 31826866 DOI: 10.2337/Db19-0942  0.512
2019 Battaglia M, Ahmed S, Anderson MS, Atkinson MA, Becker D, Bingley PJ, Bosi E, Brusko TM, DiMeglio LA, Evans-Molina C, Gitelman SE, Greenbaum CJ, Gottlieb PA, Herold KC, Hessner MJ, et al. Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes. Diabetes Care. PMID 31753960 DOI: 10.2337/Dc19-0880  0.534
2019 Peters L, Posgai A, Brusko TM. Islet-Immune Interactions in Type 1 Diabetes: The Nexus of Beta Cell Destruction. Clinical and Experimental Immunology. PMID 31309537 DOI: 10.1111/Cei.13349  0.424
2019 Ahmed S, Cerosaletti K, James E, Long SA, Mannering S, Speake C, Nakayama M, Tree T, Roep BO, Herold KC, Brusko TM. Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances. Diabetes. 68: 1366-1379. PMID 31221801 DOI: 10.2337/Db19-0119  0.457
2019 Titov AA, Baker HV, Brusko TM, Sobel ES, Morel L. Metformin Inhibits the Type 1 IFN Response in Human CD4 T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 31160534 DOI: 10.4049/Jimmunol.1801651  0.464
2019 Shapiro MR, Atkinson MA, Brusko TM. Pleiotropic roles of the insulin-like growth factor axis in type 1 diabetes. Current Opinion in Endocrinology, Diabetes, and Obesity. PMID 31145130 DOI: 10.1097/Med.0000000000000484  0.504
2019 Lewis JS, Stewart JM, Marshall GP, Carstens MR, Zhang Y, Dolgova NV, Xia C, Brusko TM, Wasserfall CH, Clare-Salzler MJ, Atkinson MA, Keselowsky BG. Dual-Sized Microparticle System for Generating Suppressive Dendritic Cells Prevents and Reverses Type 1 Diabetes in the Nonobese Diabetic Mouse Model. Acs Biomaterials Science & Engineering. 5: 2631-2646. PMID 31119191 DOI: 10.1021/Acsbiomaterials.9B00332  0.623
2019 Khosravi-Maharlooei M, Obradovic A, Misra A, Motwani K, Holzl M, Seay HR, DeWolf S, Nauman G, Danzl N, Li H, Ho SH, Winchester R, Shen Y, Brusko TM, Sykes M. Crossreactive public TCR sequences undergo positive selection in the human thymic repertoire. The Journal of Clinical Investigation. 130. PMID 30920391 DOI: 10.1172/Jci124358  0.313
2019 Van Gool F, Nguyen MLT, Mumbach MR, Satpathy AT, Rosenthal WL, Giacometti S, Le DT, Liu W, Brusko TM, Anderson MS, Rudensky AY, Marson A, Chang HY, Bluestone JA. A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells. Immunity. PMID 30709738 DOI: 10.1016/J.Immuni.2018.12.016  0.574
2019 HALLER MJ, GRECO MN, SCHATZ D, ATKINSON MA, BRUSKO TM, MATHEWS CE, JACOBSEN LM, HEROLD KC, GITELMAN SE, KRISCHER J, BUNDY BN. 164-OR: Efficacy of New-Onset Type 1 Diabetes (T1D) Intervention Trials: Variation in 1-Year Outcomes Diabetes. 68: 164-OR. DOI: 10.2337/Db19-164-Or  0.457
2019 Walker AF, Atkinson MA, Lee AM, Aulisio G, Brusko TM, Haller MJ, Schatz DA. Teaching Type 1 Diabetes: Creating Stakeholder Engagement in Biomedical Careers Through Undergraduate Research Curriculum Medical Science Educator. 30: 69-73. DOI: 10.1007/S40670-019-00877-0  0.453
2018 Marshall GP, Cserny J, Perry DJ, Yeh WI, Seay HR, Elsayed AG, Posgai AL, Brusko TM. Clinical Applications of Regulatory T cells in Adoptive Cell Therapies. Cell & Gene Therapy Insights. 4: 405-429. PMID 34984106 DOI: 10.18609/cgti.2018.042  0.308
2018 Choi SC, Titov AA, Abboud G, Seay HR, Brusko TM, Roopenian DC, Salek-Ardakani S, Morel L. Inhibition of glucose metabolism selectively targets autoreactive follicular helper T cells. Nature Communications. 9: 4369. PMID 30348969 DOI: 10.1038/S41467-018-06686-0  0.417
2018 Jacobsen LM, Newby BN, Perry DJ, Posgai AL, Haller MJ, Brusko TM. Immune Mechanisms and Pathways Targeted in Type 1 Diabetes. Current Diabetes Reports. 18: 90. PMID 30168021 DOI: 10.1007/S11892-018-1066-5  0.405
2018 Perry DJ, Wasserfall CH, Oram RA, Williams MD, Posgai A, Muir AB, Haller MJ, Schatz DA, Wallet MA, Mathews CE, Atkinson MA, Brusko TM. Application of a Genetic Risk Score to Racially Diverse Type 1 Diabetes Populations Demonstrates the Need for Diversity in Risk-Modeling. Scientific Reports. 8: 4529. PMID 29540798 DOI: 10.1038/S41598-018-22574-5  0.479
2018 YEH W, SEAY H, MATHEWS CE, BRUSKO TM. Costimulatory Molecules CD226 and TIGIT Impact CD8+ T-Cell Activity and Function during Type 1 Diabetes Diabetes. 67: 96-OR. DOI: 10.2337/Db18-96-Or  0.463
2018 CAMARGO A, PERRY DJ, BRUSKO TM, WALLET MA. SH2B3 (lnk) Regulates Type 1 Diabetes Immune Phenotypes Diabetes. 67: 224-LB. DOI: 10.2337/Db18-224-Lb  0.421
2018 SHAPIRO M, WASSERFALL C, SCHULTZ AR, MCGRAIL SM, HALLER MJ, SCHATZ D, ATKINSON MA, BRUSKO TM. Insulin-Like Growth-Factor Axis Collectively Identifies Pre–Type 1 Diabetes Diabetes. 67: 1967-P. DOI: 10.2337/Db18-1967-P  0.485
2018 ROSS JJ, WASSERFALL C, PERRY DJ, MCGRAIL KM, POSGAI AL, BRUSKO TM, SCHATZ D, HALLER MJ, ATKINSON MA. Exocrine Pancreatic Function as a Novel Biomarker in Pre-T1D Diabetes. 67: 1543-P. DOI: 10.2337/Db18-1543-P  0.515
2017 Fuchs A, Gliwiński M, Grageda N, Spiering R, Abbas AK, Appel S, Bacchetta R, Battaglia M, Berglund D, Blazar B, Bluestone JA, Bornhäuser M, Ten Brinke A, Brusko TM, Cools N, et al. Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization. Frontiers in Immunology. 8: 1844. PMID 29379498 DOI: 10.3389/Fimmu.2017.01844  0.574
2017 Yeh WI, Seay HR, Newby B, Posgai AL, Moniz FB, Michels A, Mathews CE, Bluestone JA, Brusko TM. Avidity and Bystander Suppressive Capacity of Human Regulatory T Cells Expressing De Novo Autoreactive T-Cell Receptors in Type 1 Diabetes. Frontiers in Immunology. 8: 1313. PMID 29123516 DOI: 10.3389/Fimmu.2017.01313  0.634
2017 Wallet MA, Santostefano KE, Terada N, Brusko TM. Isogenic Cellular Systems Model the Impact of Genetic Risk Variants in the Pathogenesis of Type 1 Diabetes. Frontiers in Endocrinology. 8: 276. PMID 29093700 DOI: 10.3389/Fendo.2017.00276  0.379
2017 Jacobsen LM, Posgai A, Seay HR, Haller MJ, Brusko TM. T Cell Receptor Profiling in Type 1 Diabetes. Current Diabetes Reports. 17: 118. PMID 29022222 DOI: 10.1007/S11892-017-0946-4  0.501
2017 Chen J, Chernatynskaya AV, Li JW, Kimbrell MR, Cassidy RJ, Perry DJ, Muir AB, Atkinson MA, Brusko TM, Mathews CE. T cells display mitochondria hyperpolarization in human type 1 diabetes. Scientific Reports. 7: 10835. PMID 28883439 DOI: 10.1038/S41598-017-11056-9  0.609
2017 Newby BN, Brusko TM, Zou B, Atkinson MA, Clare-Salzler M, Mathews CE. Type 1 Interferons Potentiate Human CD8(+) T Cell Cytotoxicity Through a STAT4 and Granzyme B Dependent Pathway. Diabetes. PMID 28877912 DOI: 10.2337/Db17-0106  0.621
2017 Sebastiani G, Ventriglia G, Stabilini A, Socci C, Morsiani C, Laurenzi A, Nigi L, Formichi C, Mfarrej B, Petrelli A, Fousteri G, Brusko TM, Dotta F, Battaglia M. Regulatory T-cells from pancreatic lymphnodes of patients with type-1 diabetes express increased levels of microRNA miR-125a-5p that limits CCR2 expression. Scientific Reports. 7: 6897. PMID 28761107 DOI: 10.1038/S41598-017-07172-1  0.384
2017 Marcial GE, Ford AL, Haller MJ, Gezan SA, Harrison NA, Cai D, Meyer JL, Perry DJ, Atkinson MA, Wasserfall CH, Garrett T, Gonzalez CF, Brusko TM, Dahl WJ, Lorca GL. Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults. Frontiers in Immunology. 8: 655. PMID 28659913 DOI: 10.3389/Fimmu.2017.00655  0.518
2017 Seay HR, Putnam AL, Cserny J, Posgai AL, Rosenau EH, Wingard JR, Girard KF, Kraus M, Lares AP, Brown HL, Brown KS, Balavage KT, Peters LD, Bushdorf AN, Atkinson MA, ... ... Brusko TM, et al. Expansion of Human Tregs from Cryopreserved Umbilical Cord Blood for GMP-Compliant Autologous Adoptive Cell Transfer Therapy. Molecular Therapy. Methods & Clinical Development. 4: 178-191. PMID 28345003 DOI: 10.1016/J.Omtm.2016.12.003  0.655
2017 Li X, Campbell-Thompson M, Wasserfall CH, McGrail K, Posgai A, Schultz AR, Brusko TM, Shuster J, Liang F, Muir A, Schatz D, Haller MJ, Atkinson MA. Serum Trypsinogen Levels in Type 1 Diabetes. Diabetes Care. PMID 28115475 DOI: 10.2337/Dc16-1774  0.535
2017 Lin A, Mathews C, Haller M, Brusko T, Atkinson M, Flynn R. 2431 Journal of Clinical and Translational Science. 1: 37-37. DOI: 10.1017/cts.2017.136  0.439
2016 Seay HR, Yusko E, Rothweiler SJ, Zhang L, Posgai AL, Campbell-Thompson M, Vignali M, Emerson RO, Kaddis JS, Ko D, Nakayama M, Smith MJ, Cambier JC, Pugliese A, Atkinson MA, ... ... Brusko TM, et al. Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes. Jci Insight. 1: e88242. PMID 27942583 DOI: 10.1172/Jci.Insight.88242  0.6
2016 Driver JP, Racine JJ, Ye C, Lamont DJ, Newby BN, McPhee-Leeth CG, Chapman HD, Brusko TM, Chen YG, Mathews CE, Serreze DV. Interferon gamma Limits Diabetogenic CD8 T-Cell Effector Responses in Type-1 Diabetes. Diabetes. PMID 27920091 DOI: 10.2337/Db16-0846  0.542
2016 Delitto D, Delitto AE, DiVita BB, Pham K, Han S, Hartlage ER, Newby BN, Gerber MH, Behrns KE, Moldawer LL, Thomas RM, George T, Brusko T, Mathews CE, Liu C, et al. Human pancreatic cancer cells induce a MyD88-dependent stromal response to promote a tumor-tolerant immune microenvironment. Cancer Research. PMID 27864347 DOI: 10.1158/0008-5472.Can-16-1765  0.404
2016 Haller MJ, Gitelman SE, Gottlieb PA, Michels AW, Perry DJ, Schultz AR, Hulme MA, Shuster JJ, Zou B, Wasserfall CH, Posgai A, Mathews CE, Brusko TM, Atkinson MA, Schatz DA. Anti-Thymocyte Globulin + G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders with Established Type 1 Diabetes. Diabetes. PMID 27669730 DOI: 10.2337/Db16-0823  0.575
2016 Choi SC, Hutchinson TE, Titov AA, Seay HR, Li S, Brusko TM, Croker BP, Salek-Ardakani S, Morel L. The Lupus Susceptibility Gene Pbx1 Regulates the Balance between Follicular Helper T Cell and Regulatory T Cell Differentiation. Journal of Immunology (Baltimore, Md. : 1950). PMID 27296664 DOI: 10.4049/Jimmunol.1502283  0.457
2016 Choi S, Titov AA, Yin Y, Croker BP, Sobel ES, Roopenian DC, Brusko TM, Morel L. AI-25 Glucose oxidation in lupus T cells Lupus Science & Medicine. 3. DOI: 10.1136/Lupus-2016-000179.25  0.469
2015 Haller MJ, Atkinson MA, Wasserfall CH, Brusko TM, Mathews CE, Hulme M, Cintron M, Shuster J, McGrail K, Posgai A, Schatz D. Mobilization without immune depletion fails to restore immunological tolerance or preserve beta cell function in recent onset type 1 diabetes. Clinical and Experimental Immunology. PMID 26462724 DOI: 10.1111/Cei.12731  0.58
2015 Xue S, Posgai A, Wasserfall C, Myhr C, Campbell-Thompson M, Mathews CE, Brusko T, Rabinovitch A, Savinov A, Battaglia M, Schatz D, Haller M, Atkinson M. Combination therapy reverses hyperglycemia in NOD mice with established type 1 diabetes. Diabetes. PMID 26185279 DOI: 10.2337/Db15-0164  0.573
2015 Fuhrman CA, Yeh WI, Seay HR, Saikumar Lakshmi P, Chopra G, Zhang L, Perry DJ, McClymont SA, Yadav M, Lopez MC, Baker HV, Zhang Y, Li Y, Whitley M, von Schack D, ... ... Brusko TM, et al. Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226. Journal of Immunology (Baltimore, Md. : 1950). 195: 145-55. PMID 25994968 DOI: 10.4049/Jimmunol.1402381  0.752
2015 Yin Y, Choi SC, Xu Z, Perry DJ, Seay H, Croker BP, Sobel ES, Brusko TM, Morel L. Normalization of CD4+ T cell metabolism reverses lupus. Science Translational Medicine. 7: 274ra18. PMID 25673763 DOI: 10.1126/Scitranslmed.Aaa0835  0.427
2015 Haller MJ, Gitelman SE, Gottlieb PA, Michels AW, Rosenthal SM, Shuster JJ, Zou B, Brusko TM, Hulme MA, Wasserfall CH, Mathews CE, Atkinson MA, Schatz DA. Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes. The Journal of Clinical Investigation. 125: 448-55. PMID 25500887 DOI: 10.1172/Jci78492  0.535
2015 Fuhrman CA, Yeh WI, Seay HR, Lakshmi PS, Chopra G, Zhang L, Perry DJ, McClymont SA, Yadav M, Lopez MC, Baker HV, Zhang Y, Li Y, Whitley M, Von Schack D, ... ... Brusko TM, et al. Divergent phenotypes of human regulatory T cells expressing the receptors TIGIT and CD226 Journal of Immunology. 195: 145-155. DOI: 10.4049/jimmunol.1402381  0.686
2014 Sarkar D, Biswas M, Liao G, Seay HR, Perrin GQ, Markusic DM, Hoffman BE, Brusko TM, Terhorst C, Herzog RW. Ex Vivo Expanded Autologous Polyclonal Regulatory T Cells Suppress Inhibitor Formation in Hemophilia. Molecular Therapy. Methods & Clinical Development. 1. PMID 25364772 DOI: 10.1038/Mtm.2014.30  0.441
2014 Lewis JS, Roche C, Zhang Y, Brusko TM, Wasserfall CH, Atkinson M, Clare-Salzler MJ, Keselowsky BG. Combinatorial delivery of immunosuppressive factors to dendritic cells using dual-sized microspheres. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 2: 2562-2574. PMID 24778809 DOI: 10.1039/C3Tb21460E  0.529
2013 Gjymishka A, Coman RM, Brusko TM, Glover SC. Influence of host immunoregulatory genes, ER stress and gut microbiota on the shared pathogenesis of inflammatory bowel disease and Type 1 diabetes. Immunotherapy. 5: 1357-66. PMID 24283846 DOI: 10.2217/Imt.13.130  0.341
2013 Mueller C, Chulay JD, Trapnell BC, Humphries M, Carey B, Sandhaus RA, McElvaney NG, Messina L, Tang Q, Rouhani FN, Campbell-Thompson M, Fu AD, Yachnis A, Knop DR, Ye GJ, ... ... Brusko TM, et al. Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression. The Journal of Clinical Investigation. 123: 5310-8. PMID 24231351 DOI: 10.1172/Jci70314  0.366
2013 Myhr CB, Hulme MA, Wasserfall CH, Hong PJ, Lakshmi PS, Schatz DA, Haller MJ, Brusko TM, Atkinson MA. The autoimmune disease-associated SNP rs917997 of IL18RAP controls IFNγ production by PBMC. Journal of Autoimmunity. 44: 8-12. PMID 23891168 DOI: 10.1016/J.Jaut.2013.06.001  0.51
2013 Haller MJ, Wasserfall CH, Hulme MA, Cintron M, Brusko TM, McGrail KM, Wingard JR, Theriaque DW, Shuster JJ, Ferguson RJ, Kozuch M, Clare-Salzler M, Atkinson MA, Schatz DA. Autologous umbilical cord blood infusion followed by oral docosahexaenoic acid and vitamin D supplementation for C-peptide preservation in children with Type 1 diabetes. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 19: 1126-9. PMID 23611977 DOI: 10.1016/J.Bbmt.2013.04.011  0.528
2013 Cabrera R, Ararat M, Xu Y, Brusko T, Wasserfall C, Atkinson MA, Chang LJ, Liu C, Nelson DR. Immune modulation of effector CD4+ and regulatory T cell function by sorafenib in patients with hepatocellular carcinoma. Cancer Immunology, Immunotherapy : Cii. 62: 737-46. PMID 23223899 DOI: 10.1007/S00262-012-1380-8  0.572
2012 Cabrera R, Fitian AI, Ararat M, Xu Y, Brusko T, Wasserfall C, Atkinson MA, Liu C, Nelson DR. Serum levels of soluble CD25 as a marker for hepatocellular carcinoma. Oncology Letters. 4: 840-846. PMID 23205111 DOI: 10.3892/Ol.2012.826  0.423
2012 Thompson JA, Perry D, Brusko TM. Autologous regulatory T cells for the treatment of type 1 diabetes. Current Diabetes Reports. 12: 623-32. PMID 22843491 DOI: 10.1007/S11892-012-0304-5  0.479
2012 Hulme MA, Wasserfall CH, Atkinson MA, Brusko TM. Central role for interleukin-2 in type 1 diabetes. Diabetes. 61: 14-22. PMID 22187370 DOI: 10.2337/Db11-1213  0.582
2012 Sarkar D, Markusic DM, Terhorst C, Brusko T, Herzog RW. Suppression of Inhibitor Formation in Protein and Gene Therapy for Hemophilia Using Ex Vivo Expanded Treg Blood. 120: 13-13. DOI: 10.1182/Blood.V120.21.13.13  0.375
2011 Ararat MA, Fitian AI, Brusko T, Xu Y, Wasserfall C, Atkinson M, Liu C, Allegra CJ, Nelson D, Cabrera R. The soluble form of the IL-2 receptor (sCD25) as a novel biomarker for hepatocellular carcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: e14629. PMID 28021352 DOI: 10.1200/Jco.2011.29.15_Suppl.E14629  0.432
2011 Haller MJ, Wasserfall CH, Hulme MA, Cintron M, Brusko TM, McGrail KM, Sumrall TM, Wingard JR, Theriaque DW, Shuster JJ, Atkinson MA, Schatz DA. Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptide. Diabetes Care. 34: 2567-9. PMID 22011412 DOI: 10.2337/Dc11-1406  0.504
2011 Sobel ES, Brusko TM, Butfiloski EJ, Hou W, Li S, Cuda CM, Abid AN, Reeves WH, Morel L. Defective response of CD4(+) T cells to retinoic acid and TGFβ in systemic lupus erythematosus. Arthritis Research & Therapy. 13: R106. PMID 21708033 DOI: 10.1186/Ar3387  0.43
2011 McClymont SA, Putnam AL, Lee MR, Esensten JH, Liu W, Hulme MA, Hoffmüller U, Baron U, Olek S, Bluestone JA, Brusko TM. Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes. Journal of Immunology (Baltimore, Md. : 1950). 186: 3918-26. PMID 21368230 DOI: 10.4049/Jimmunol.1003099  0.641
2011 Golovina TN, Mikheeva T, Brusko TM, Blazar BR, Bluestone JA, Riley JL. Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells. Plos One. 6: e15868. PMID 21253593 DOI: 10.1371/Journal.Pone.0015868  0.593
2011 Cabrera R, Ararat M, Cao M, Xu Y, Wasserfall C, Brusko T, Atkinson MA, Liu C, Nelson DR. Abstract 2702: Sorafenib modulates immune responses in patients with hepatocellular carcinoma Cancer Research. 71: 2702-2702. DOI: 10.1158/1538-7445.Am2011-2702  0.521
2010 Brusko TM, Koya RC, Zhu S, Lee MR, Putnam AL, McClymont SA, Nishimura MI, Han S, Chang LJ, Atkinson MA, Ribas A, Bluestone JA. Human antigen-specific regulatory T cells generated by T cell receptor gene transfer. Plos One. 5: e11726. PMID 20668510 DOI: 10.1371/Journal.Pone.0011726  0.669
2010 Brusko T, Koya R, Zhu S, Lee M, Putnam A, McClymont S, Nishimura M, Xia N, Bluestone J. Lentiviral TCR-engineered Tregs Demonstrate Effective Suppression of T Cell Responses Clinical Immunology. 135: S30. DOI: 10.1016/J.Clim.2010.03.093  0.547
2010 Putnam A, Lee M, Liu W, Escosa H, Brusko T, Bluestone J. The Use of CD4+CD127lo/-CD25+ Polyclonal Tregs for the Treatment of Recent Onset T1D in a Phase I Clinical Trial Clinical Immunology. 135: S23. DOI: 10.1016/J.Clim.2010.03.073  0.524
2010 McClymont S, Putnam A, Lee M, Esensten J, Liu W, Olek S, Baron U, Hoffmuller U, Bluestone J, Brusko T. Plasticity of Human Regulatory T Cells - Characterization of IFN-γ-Producing Cells Clinical Immunology. 135: S5-S6. DOI: 10.1016/J.Clim.2010.03.023  0.564
2009 Brusko TM, Wasserfall CH, Hulme MA, Cabrera R, Schatz D, Atkinson MA. Influence of membrane CD25 stability on T lymphocyte activity: implications for immunoregulation. Plos One. 4: e7980. PMID 19956753 DOI: 10.1371/Journal.Pone.0007980  0.58
2009 Brusko TM, Bluestone JA. Regulatory T cells directed to the site of the action. Proceedings of the National Academy of Sciences of the United States of America. 106: 20553-4. PMID 19955436 DOI: 10.1073/Pnas.0911848107  0.566
2009 Haller MJ, Wasserfall CH, McGrail KM, Cintron M, Brusko TM, Wingard JR, Kelly SS, Shuster JJ, Atkinson MA, Schatz DA. Autologous umbilical cord blood transfusion in very young children with type 1 diabetes. Diabetes Care. 32: 2041-6. PMID 19875605 DOI: 10.2337/Dc09-0967  0.5
2009 Brusko TM. Mesenchymal stem cells: a potential border patrol for transplanted islets? Diabetes. 58: 1728-9. PMID 19638531 DOI: 10.2337/Db09-0749  0.396
2009 Putnam AL, Brusko TM, Lee MR, Liu W, Szot GL, Ghosh T, Atkinson MA, Bluestone JA. Expansion of human regulatory T-cells from patients with type 1 diabetes. Diabetes. 58: 652-62. PMID 19074986 DOI: 10.2337/Db08-1168  0.685
2009 Putnam A, McClymont S, Brusko T, Lee M, Liu W, Ghosh T, Bluestone J. T.115. Stability and Purity of Expanded Human CD4+CD127lo/-CD25+Tregs for Use in Cellular Therapy for the Treatment of Type 1 Diabetes Clinical Immunology. 131: S84-S85. DOI: 10.1016/J.Clim.2009.03.248  0.609
2009 Brusko T, Zhu S, Putnam A, Lee M, McClymont S, Liu W, Nishimura M, Koya R, Tree T, Riley J, Bluestone J. OR.105. Development of Engineered Antigen-specific Human Regulatory T Cells for the Treatment of Type 1 Diabetes by TCR Gene Transfer Clinical Immunology. 131: S42-S43. DOI: 10.1016/J.Clim.2009.03.120  0.598
2008 Xue S, Wasserfall CH, Parker M, Brusko TM, McGrail S, McGrail K, Moore M, Campbell-Thompson M, Schatz DA, Atkinson MA, Haller MJ. Exendin-4 therapy in NOD mice with new-onset diabetes increases regulatory T cell frequency. Annals of the New York Academy of Sciences. 1150: 152-6. PMID 19120286 DOI: 10.1196/Annals.1447.049  0.59
2008 Stalvey MS, Brusko TM, Mueller C, Wasserfall CH, Schatz DA, Atkinson MA, Flotte TR. CFTR mutations impart elevated immune reactivity in a murine model of cystic fibrosis related diabetes. Cytokine. 44: 154-9. PMID 18778952 DOI: 10.1016/J.Cyto.2008.07.468  0.488
2008 Brusko TM, Putnam AL, Bluestone JA. Human regulatory T cells: role in autoimmune disease and therapeutic opportunities. Immunological Reviews. 223: 371-90. PMID 18613848 DOI: 10.1111/J.1600-065X.2008.00637.X  0.564
2008 George JF, Braun A, Brusko TM, Joseph R, Bolisetty S, Wasserfall CH, Atkinson MA, Agarwal A, Kapturczak MH. Suppression by CD4+CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigen-presenting cells. The American Journal of Pathology. 173: 154-60. PMID 18511516 DOI: 10.2353/Ajpath.2008.070963  0.589
2008 Brusko T, Bluestone J. Clinical application of regulatory T cells for treatment of type 1 diabetes and transplantation. European Journal of Immunology. 38: 931-4. PMID 18395864 DOI: 10.1002/Eji.200738108  0.589
2008 Haller MJ, Viener HL, Wasserfall C, Brusko T, Atkinson MA, Schatz DA. Autologous umbilical cord blood infusion for type 1 diabetes. Experimental Hematology. 36: 710-5. PMID 18358588 DOI: 10.1016/J.Exphem.2008.01.009  0.517
2008 Simon G, Parker M, Ramiya V, Wasserfall C, Huang Y, Bresson D, Schwartz RF, Campbell-Thompson M, Tenace L, Brusko T, Xue S, Scaria A, Lukason M, Eisenbeis S, Williams J, et al. Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time-dependent induction of immunoregulation. Diabetes. 57: 405-14. PMID 18039815 DOI: 10.2337/Db06-1384  0.532
2007 Brusko TM, Hulme MA, Myhr CB, Haller MJ, Atkinson MA. Assessing the in vitro suppressive capacity of regulatory T cells. Immunological Investigations. 36: 607-28. PMID 18161521 DOI: 10.1080/08820130701790368  0.555
2007 Brusko T, Atkinson M. Treg in type 1 diabetes. Cell Biochemistry and Biophysics. 48: 165-75. PMID 17709886 DOI: 10.1007/S12013-007-0018-5  0.615
2007 Lowe CE, Cooper JD, Brusko T, Walker NM, Smyth DJ, Bailey R, Bourget K, Plagnol V, Field S, Atkinson M, Clayton DG, Wicker LS, Todd JA. Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes. Nature Genetics. 39: 1074-82. PMID 17676041 DOI: 10.1038/Ng2102  0.498
2007 Brusko T, Wasserfall C, McGrail K, Schatz R, Viener HL, Schatz D, Haller M, Rockell J, Gottlieb P, Clare-Salzler M, Atkinson M. No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes. Diabetes. 56: 604-12. PMID 17327427 DOI: 10.2337/Db06-1248  0.595
2007 Brusko T, Wasserfall C, McGrail K, Moore M, Huegel A, Schatz D, Atkinson M. Regulatory T Cells Require Serum for Suppression of Effector T Cell Proliferation and Express Stable Membrane-bound CD25 Clinical Immunology. 123: S4. DOI: 10.1016/J.Clim.2007.03.183  0.573
2006 Scumpia PO, Delano MJ, Kelly KM, O'Malley KA, Efron PA, McAuliffe PF, Brusko T, Ungaro R, Barker T, Wynn JL, Atkinson MA, Reeves WH, Salzler MJ, Moldawer LL. Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis. Journal of Immunology (Baltimore, Md. : 1950). 177: 7943-9. PMID 17114466 DOI: 10.4049/Jimmunol.177.11.7943  0.584
2006 Araya CE, Wasserfall CH, Brusko TM, Mu W, Segal MS, Johnson RJ, Garin EH. A case of unfulfilled expectations. Cytokines in idiopathic minimal lesion nephrotic syndrome. Pediatric Nephrology (Berlin, Germany). 21: 603-10. PMID 16525836 DOI: 10.1007/S00467-006-0026-5  0.372
2006 Burkhardt BR, Greene SR, White P, Wong RK, Brestelli JE, Yang J, Robert CE, Brusko TM, Wasserfall CH, Wu J, Atkinson MA, Gao Z, Kaestner KH, Wolf BA. PANDER-induced cell-death genetic networks in islets reveal central role for caspase-3 and cyclin-dependent kinase inhibitor 1A (p21). Gene. 369: 134-41. PMID 16412588 DOI: 10.1016/J.Gene.2005.10.040  0.473
2005 Brusko TM, Wasserfall CH, Clare-Salzler MJ, Schatz DA, Atkinson MA. Functional defects and the influence of age on the frequency of CD4 +CD25+ T-cells in type 1 diabetes Diabetes. 54: 1407-1414. PMID 15855327 DOI: 10.2337/Diabetes.54.5.1407  0.629
2005 Brusko TM, Wasserfall CH, Agarwal A, Kapturczak MH, Atkinson MA. An integral role for heme oxygenase-1 and carbon monoxide in maintaining peripheral tolerance by CD4+CD25+ regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 174: 5181-6. PMID 15843512 DOI: 10.4049/Jimmunol.174.9.5181  0.575
2005 Morales A, Wasserfall C, Brusko T, Carter C, Schatz D, Silverstein J, Ellis T, Atkinson M. Adiponectin and leptin concentrations may aid in discriminating disease forms in children and adolescents with type 1 and type 2 diabetes. Diabetes Care. 27: 2010-4. PMID 15277432 DOI: 10.2337/Diacare.27.8.2010  0.533
2004 Haller MJ, Samyn M, Nichols WW, Brusko T, Wasserfall C, Schwartz RF, Atkinson M, Shuster JJ, Pierce GL, Silverstein JH. Radial artery tonometry demonstrates arterial stiffness in children with type 1 diabetes Diabetes Care. 27: 2911-2917. PMID 15562206 DOI: 10.2337/Diacare.27.12.2911  0.494
2004 You S, Chen C, Lee WH, Brusko T, Atkinson M, Liu CP. Presence of diabetes-inhibiting, glutamic acid decarboxylase-specific, IL-10-dependent, regulatory T cells in naive nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 173: 6777-85. PMID 15557171 DOI: 10.4049/Jimmunol.173.11.6777  0.597
2004 Kapturczak MH, Wasserfall C, Brusko T, Campbell-Thompson M, Ellis TM, Atkinson MA, Agarwal A. Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse. The American Journal of Pathology. 165: 1045-53. PMID 15331427 DOI: 10.1016/S0002-9440(10)63365-2  0.5
2004 Guo D, Li M, Zhang Y, Yang P, Eckenrode S, Hopkins D, Zheng W, Purohit S, Podolsky RH, Muir A, Wang J, Dong Z, Brusko T, Atkinson M, Pozzilli P, et al. A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes. Nature Genetics. 36: 837-41. PMID 15247916 DOI: 10.1038/Ng1391  0.483
2004 Zhang YC, Powers M, Wasserfall C, Brusko T, Song S, Flotte T, Snyder RO, Potter M, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Nick HS, Agarwal A, Ellis TM, Atkinson MA. Immunity to adeno-associated virus serotype 2 delivered transgenes imparted by genetic predisposition to autoimmunity. Gene Therapy. 11: 233-40. PMID 14737082 DOI: 10.1038/Sj.Gt.3302144  0.485
2004 Guo D, Li M, Zhang Y, Yang P, Eckenrode S, Hopkins D, Zheng W, Purohit S, Podolsky RH, Muir A, Wang J, Dong Z, Brusko T, Atkinson M, Pozzilli P, et al. Erratum: Corrigendum: A functional variant of SUMO4, a new IκBα modifier, is associated with type 1 diabetes Nature Genetics. 36: 1024-1024. DOI: 10.1038/Ng0904-1024B  0.486
2003 Goudy KS, Burkhardt BR, Wasserfall C, Song S, Campbell-Thompson ML, Brusko T, Powers MA, Clare-Salzler MJ, Sobel ES, Ellis TM, Flotte TR, Atkinson MA. Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion. Journal of Immunology (Baltimore, Md. : 1950). 171: 2270-8. PMID 12928371 DOI: 10.4049/Jimmunol.171.5.2270  0.59
2003 Zhang YC, Pileggi A, Agarwal A, Molano RD, Powers M, Brusko T, Wasserfall C, Goudy K, Zahr E, Poggioli R, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Nick H, Flotte T, et al. Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice. Diabetes. 52: 708-16. PMID 12606512 DOI: 10.2337/Diabetes.52.3.708  0.526
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