Manoj K Kashyap, PhD - Publications

Affiliations: 
2019- Stem Cell Institute Amity University Haryana 
Area:
RNA Splicing, Tumor-microenvironment, and Natural products for Cancer Therapeutics Development
Website:
https://manojkkashyap.wixsite.com/thekashyaplab

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kashyap MK, Karathia H, Kumar D, Vera Alvarez R, Forero-Forero JV, Moreno E, Lujan JV, Amaya-Chanaga CI, Vidal NM, Yu Z, Ghia EM, Lengerke-Diaz PA, Achinko D, Choi MY, Rassenti LZ, et al. Aberrant spliceosome activity via elevated intron retention and upregulation and phosphorylation of SF3B1 in chronic lymphocytic leukemia. Molecular Therapy. Nucleic Acids. 35: 102202. PMID 38846999 DOI: 10.1016/j.omtn.2024.102202  0.314
2024 Krishnia L, Kashyap MK. Development of Compendium for Esophageal Squamous Cell Carcinoma. Journal of Visualized Experiments : Jove. PMID 38682946 DOI: 10.3791/65480  0.319
2022 Kumar D, Kashyap MK, Yu Z, Spaanderman I, Villa R, Kipps TJ, La Clair JJ, Burkart MD, Castro JE. Modulation of RNA splicing associated with Wnt signaling pathway using FD-895 and pladienolide B. Aging. 14: 2081-2100. PMID 35230971 DOI: 10.18632/aging.203924  0.735
2019 Rao R, Husain A, Bharti AC, Kashyap MK. Discovery of a novel connecting link between Renin-Angiotensin System and cancer in Barrett's Esophagus by Proteomic screening Proteomics Clin Appl. PMID 30891939 DOI: 10.1002/Prca.201900006  0.342
2018 Tungekar A, Mandarthi S, Mandaviya PR, Gadekar VP, Tantry A, Kotian S, Reddy J, Prabha D, Bhat S, Sahay S, Mascarenhas R, Badkillaya RR, Nagasampige MK, Yelnadu M, Pawar H, ... ... Kashyap MK, et al. ESCC ATLAS: A population wide compendium of biomarkers for Esophageal Squamous Cell Carcinoma. Scientific Reports. 8: 12715. PMID 30143675 DOI: 10.1038/S41598-018-30579-3  0.359
2018 Barbhuiya MA, Kashyap MK, Puttamallesh VN, Kumar RV, Wu X, Pandey A, Gowda H. Identification of spleen tyrosine kinase as a potential therapeutic target for esophageal squamous cell carcinoma using reverse phase protein arrays. Oncotarget. 9: 18422-18434. PMID 29719615 DOI: 10.18632/Oncotarget.24853  0.532
2017 Kashyap MK, Amaya-Chanaga CI, Kumar D, Simmons B, Huser N, Gu Y, Hallin M, Lindquist K, Yafawi R, Choi MY, Amine AA, Rassenti LZ, Zhang C, Liu SH, Smeal T, et al. Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia. Journal of Hematology & Oncology. 10: 112. PMID 28526063 DOI: 10.1186/S13045-017-0435-X  0.325
2017 Leon B, Kashyap M, Chan W, Krug K, Castro J, LaClair J, Burkart MD. A Challenging Pie to Splice: Drugging the Spliceosome. Angewandte Chemie (International Ed. in English). PMID 28371109 DOI: 10.1002/Anie.201701065  0.55
2017 Zhang X, Maity T, Kashyap MK, Bansal M, Venugopalan A, Singh S, Awasthi S, Marimuthu A, Jacob HK, Belkina N, Pitts S, Cultraro CM, Gao S, Kirkali F, Biswas R, et al. Quantitative tyrosine phosphoproteomics of EGFR tyrosine kinase inhibitor-treated lung adenocarcinoma cells reveals potential novel biomarkers of therapeutic response. Molecular & Cellular Proteomics : McP. PMID 28331001 DOI: 10.1074/Mcp.M117.067439  0.437
2017 León B, Kashyap MK, Chan WC, Krug KA, Castro JE, La Clair JJ, Burkart MD. Das Spliceosom als Angriffspunkt für Pharmaka Angewandte Chemie. 129: 12218-12230. DOI: 10.1002/Ange.201701065  0.444
2016 Barile E, Marconi GD, De SK, Baggio C, Gambini L, Salem AF, Kashyap MK, Castro JE, Kipps TJ, Pellecchia M. hBfl-1/hNOXA Interaction Studies Provide New Insights on the Role of Bfl-1 in Cancer Cell Resistance and for the Design of Novel Anticancer Agents. Acs Chemical Biology. PMID 28026162 DOI: 10.1021/Acschembio.6B00962  0.404
2016 Choi MY, Kashyap MK, Kumar D. The chronic lymphocytic leukemia microenvironment: Beyond the B-cell receptor. Best Practice & Research. Clinical Haematology. 29: 40-53. PMID 27742071 DOI: 10.1016/J.Beha.2016.08.007  0.358
2016 Kumar D, Kashyap MK, La Clair JJ, Villa R, Spaanderman I, Chien S, Rassenti LZ, Kipps TJ, Burkart MD, Castro JE. Selectivity in Small Molecule Splicing Modulation. Acs Chemical Biology. PMID 27499047 DOI: 10.1021/Acschembio.6B00399  0.733
2016 Dhar S, La Clair JJ, León B, Hammons JC, Yu Z, Kashyap MK, Castro JE, Burkart MD. A Carbohydrate-Derived Splice Modulator. Journal of the American Chemical Society. PMID 27058259 DOI: 10.1021/Jacs.5B13427  0.577
2015 Pawar H, Srikanth SM, Kashyap MK, Sathe G, Chavan S, Singal M, Manju HC, Kumar KV, Vijayakumar M, Sirdeshmukh R, Pandey A, Prasad TS, Gowda H, Kumar RV. Downregulation of S100 Calcium Binding Protein A9 in Esophageal Squamous Cell Carcinoma. Thescientificworldjournal. 2015: 325721. PMID 26788548 DOI: 10.1155/2015/325721  0.487
2015 Kashyap MK, Kumar D, Jones H, Amaya-Chanaga CI, Choi MY, Melo-Cardenas J, Ale-Ali A, Kuhne MR, Sabbatini P, Cohen LJ, Shelat SG, Rassenti LZ, Kipps TJ, Cardarelli PM, Castro JE. Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway. Oncotarget. PMID 26646452 DOI: 10.18632/Oncotarget.6465  0.365
2015 Wu X, Zahari MS, Ma B, Liu R, Renuse S, Sahasrabuddhe NA, Chen L, Chaerkady R, Kim MS, Zhong J, Jelinek C, Barbhuiya MA, Leal-Rojas P, Yang Y, Kashyap MK, et al. Global phosphotyrosine survey in triple-negative breast cancer reveals activation of multiple tyrosine kinase signaling pathways. Oncotarget. PMID 26356563 DOI: 10.18632/Oncotarget.5020  0.524
2015 Kashyap MK, Kumar D, Villa R, La Clair JJ, Benner C, Sasik R, Jones H, Ghia EM, Rassenti LZ, Kipps TJ, Burkart MD, Castro JE. Targeting the spliceosome in chronic lymphocytic leukemia with the macrolides FD-895 and pladienolide-B. Haematologica. 100: 945-54. PMID 25862704 DOI: 10.3324/Haematol.2014.122069  0.746
2015 Kashyap MK, Amaya-Chanaga CI, Kumar D, Choi MY, Rassenti LZ, Ale-Ali A, Liu S, Smeal T, Fantin V, Kipps TJ, Pernasetti F, Castro JE. Targeting the CXCR4-CXCL12 Pathway Using an Anti-CXCR4 IgG1 Antibody (PF-06747143) in Chronic Lymphocytic Leukemia Blood. 126: 4162-4162. DOI: 10.1182/Blood.V126.23.4162.4162  0.374
2013 Villa R, Kashyap MK, Kumar D, Kipps TJ, Castro JE, La Clair JJ, Burkart MD. Stabilized cyclopropane analogs of the splicing inhibitor FD-895. Journal of Medicinal Chemistry. 56: 6576-82. PMID 23919277 DOI: 10.1021/Jm400861T  0.739
2013 Marimuthu A, Subbannayya Y, Sahasrabuddhe NA, Balakrishnan L, Syed N, Sekhar NR, Katte TV, Pinto SM, Srikanth SM, Kumar P, Pawar H, Kashyap MK, Maharudraiah J, Ashktorab H, Smoot DT, et al. SILAC-based quantitative proteomic analysis of gastric cancer secretome. Proteomics. Clinical Applications. 7: 355-66. PMID 23161554 DOI: 10.1002/Prca.201200069  0.485
2013 Pawar H, Maharudraiah J, Kashyap MK, Sharma J, Srikanth SM, Choudhary R, Chavan S, Sathe G, Manju HC, Kumar KV, Vijayakumar M, Sirdeshmukh R, Harsha HC, Prasad TS, Pandey A, et al. Downregulation of cornulin in esophageal squamous cell carcinoma. Acta Histochemica. 115: 89-99. PMID 22560086 DOI: 10.1016/J.Acthis.2012.04.003  0.49
2013 Kumar D, Kashyap MK, Spaanderman I, Villa R, Rassenti L, La Clair J, Burkat MD, Kipps TJ, Castro JE. A Cyclopropane-Derived Stable Analog Of Fd-895 Induces Apoptosis and Inhibition Of mRNA Splicing In Lymphoma and Chronic Lymphocytic Leukemia: A Novel Therapeutic Approach Blood. 122: 2884-2884. DOI: 10.1182/Blood.V122.21.2884.2884  0.72
2012 Kumar GS, Venugopal AK, Kashyap MK, Raju R, Marimuthu A, Palapetta SM, Subbanayya Y, Goel R, Chawla A, Dikshit JB, Tata P, Harsha HC, Maharudraiah J, Ramachandra YL, Satishchandra P, et al. Gene Expression Profiling of Tuberculous Meningitis Co-infected with HIV. Journal of Proteomics & Bioinformatics. 5: 235-244. PMID 27053842 DOI: 10.4172/Jpb.1000243  0.412
2012 Telikicherla D, Maharudraiah J, Pawar H, Marimuthu A, Kashyap MK, Ramachandra YL, Roa JC, Pandey A. Overexpression of Kinesin Associated Protein 3 (KIFAP3) in Breast Cancer. Journal of Proteomics & Bioinformatics. 5: 122-126. PMID 26843789 DOI: 10.4172/Jpb.1000223  0.498
2012 Kashyap MK, Pawar HA, Keerthikumar S, Sharma J, Goel R, Mahmood R, Kumar MV, Kumar KV, Pandey A, Kumar RV, Prasad TS, Harsha HC. Evaluation of protein expression pattern of stanniocalcin 2, insulin-like growth factor-binding protein 7, inhibin beta A and four and a half LIM domains 1 in esophageal squamous cell carcinoma. Cancer Biomarkers : Section a of Disease Markers. 12: 1-9. PMID 23321464 DOI: 10.3233/Cbm-120289  0.498
2012 Kim MS, Kuppireddy SV, Sakamuri S, Singal M, Getnet D, Harsha HC, Goel R, Balakrishnan L, Jacob HK, Kashyap MK, Tankala SG, Maitra A, Iacobuzio-Donahue CA, Jaffee E, Goggins MG, et al. Rapid characterization of candidate biomarkers for pancreatic cancer using cell microarrays (CMAs). Journal of Proteome Research. 11: 5556-63. PMID 22985314 DOI: 10.1021/Pr300483R  0.532
2012 Telikicherla D, Marimuthu A, Kashyap MK, Ramachandra YL, Mohan S, Roa JC, Maharudraiah J, Pandey A. Overexpression of ribosome binding protein 1 (RRBP1) in breast cancer. Clinical Proteomics. 9: 7. PMID 22709790 DOI: 10.1186/1559-0275-9-7  0.504
2012 Kashyap MK, Kumar D, Jones HJ, Schwaederlé M, Ghia EM, Villa R, La Clair JJ, Burkart MD, Kipps TJ, Castro JE. Fd-895 and Pladienolide B Inhibit mRNA Splicing and Induce Apoptosis in Chronic Lymphocytic Leukemia Blood. 120: 3890-3890. DOI: 10.1182/Blood.V120.21.3890.3890  0.584
2012 Wu X, Renuse S, Chen L, Chaerkady R, Kim M, Zahari S, Sahasrabuddhe N, Zhong J, Yang Y, Kashyap M, Marimuthu A, Ling M, Fackler MJ, Merino V, Zhang Z, et al. Abstract 4797: Global phosphotyrosine survey reveals the evidence of activation of multiple tyrosine kinase signaling pathways in basal-like breast cancer cells Cancer Research. 72: 4797-4797. DOI: 10.1158/1538-7445.Am2012-4797  0.52
2012 Kim M, Chaerkady R, Wu X, O'meally R, Kuppireddy SV, Zhong J, Jacob HK, Marimuthu A, Kashyap MK, Cole R, Iacobuzio-Donahue C, Maitra A, Pandey A. Abstract 1269: Activation of diverse signaling pathways in pancreatic cancer revealed by phosphoproteomics Cancer Research. 72: 1269-1269. DOI: 10.1158/1538-7445.Am2012-1269  0.523
2011 Marimuthu A, Jacob HK, Jakharia A, Subbannayya Y, Keerthikumar S, Kashyap MK, Goel R, Balakrishnan L, Dwivedi S, Pathare S, Dikshit JB, Maharudraiah J, Singh S, Sameer Kumar GS, Vijayakumar M, et al. Gene Expression Profiling of Gastric Cancer. Journal of Proteomics & Bioinformatics. 4: 74-82. PMID 27030788 DOI: 10.4172/Jpb.1000170  0.488
2011 Pawar H, Kashyap MK, Sahasrabuddhe NA, Renuse S, Harsha HC, Kumar P, Sharma J, Kandasamy K, Marimuthu A, Nair B, Rajagopalan S, Maharudraiah J, Premalatha CS, Kumar KV, Vijayakumar M, et al. Quantitative tissue proteomics of esophageal squamous cell carcinoma for novel biomarker discovery. Cancer Biology & Therapy. 12: 510-22. PMID 21743296 DOI: 10.4161/Cbt.12.6.16833  0.496
2010 Kashyap MK, Marimuthu A, Peri S, Kumar GS, Jacob HK, Prasad TS, Mahmood R, Kumar KV, Kumar MV, Meltzer SJ, Montgomery EA, Kumar RV, Pandey A. Overexpression of periostin and lumican in esophageal squamous cell carcinoma. Cancers. 2: 133-42. PMID 24281036 DOI: 10.3390/Cancers2010133  0.487
2010 Kashyap MK, Harsha HC, Renuse S, Pawar H, Sahasrabuddhe NA, Kim MS, Marimuthu A, Keerthikumar S, Muthusamy B, Kandasamy K, Subbannayya Y, Prasad TS, Mahmood R, Chaerkady R, Meltzer SJ, et al. SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome. Cancer Biology & Therapy. 10: 796-810. PMID 20686364 DOI: 10.4161/Cbt.10.8.12914  0.49
2010 Kim M, Kuppireddy SV, Zhong J, Jacob HK, Marimuthu A, Kashyap MK, Pandey A. Abstract A58: Activation of diverse signaling pathways in pancreatic cancer revealed by phosphoproteomics Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-A58  0.529
2009 Harsha HC, Kandasamy K, Ranganathan P, Rani S, Ramabadran S, Gollapudi S, Balakrishnan L, Dwivedi SB, Telikicherla D, Selvan LD, Goel R, Mathivanan S, Marimuthu A, Kashyap M, Vizza RF, et al. A compendium of potential biomarkers of pancreatic cancer. Plos Medicine. 6: e1000046. PMID 19360088 DOI: 10.1371/Journal.Pmed.1000046  0.452
2009 Chaerkady R, Kerr CL, Marimuthu A, Kelkar DS, Kashyap MK, Gucek M, Gearhart JD, Pandey A. Temporal analysis of neural differentiation using quantitative proteomics. Journal of Proteome Research. 8: 1315-26. PMID 19173612 DOI: 10.1021/Pr8006667  0.442
2009 Keshava Prasad TS, Goel R, Kandasamy K, Keerthikumar S, Kumar S, Mathivanan S, Telikicherla D, Raju R, Shafreen B, Venugopal A, Balakrishnan L, Marimuthu A, Banerjee S, Somanathan DS, Sebastian A, ... ... Kashyap MK, et al. Human Protein Reference Database--2009 update. Nucleic Acids Research. 37: D767-72. PMID 18988627 DOI: 10.1093/Nar/Gkn892  0.449
2009 Kashyap MK, Marimuthu A, Kishore CJ, Peri S, Keerthikumar S, Prasad TS, Mahmood R, Rao S, Ranganathan P, Sanjeeviah RC, Vijayakumar M, Kumar KV, Montgomery EA, Kumar RV, Pandey A. Genomewide mRNA profiling of esophageal squamous cell carcinoma for identification of cancer biomarkers. Cancer Biology & Therapy. 8: 36-46. PMID 18981721 DOI: 10.4161/Cbt.8.1.7090  0.551
2008 Guha U, Chaerkady R, Marimuthu A, Patterson AS, Kashyap MK, Harsha HC, Sato M, Bader JS, Lash AE, Minna JD, Pandey A, Varmus HE. Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS. Proceedings of the National Academy of Sciences of the United States of America. 105: 14112-7. PMID 18776048 DOI: 10.1073/Pnas.0806158105  0.476
2005 Kashyap MK, Kumar A, Emelianenko N, Kashyap A, Kaushik R, Huang R, Khullar M, Sharma SK, Singh SK, Bhargave AK, Upadhyaya SK. Biochemical and molecular markers in renal cell carcinoma: an update and future prospects. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 10: 258-94. PMID 16191485 DOI: 10.1080/13547500500218534  0.329
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