Haruo Kasai, Ph.D./M.D. - Publications

Affiliations: 
2005- Center for Disease Biology and Integrative Medicine The University of Tokyo, Bunkyō-ku, Tōkyō-to, Japan 
 2017- The University of Tokyo, International Research Center for Neurointelligence 
Area:
Spine
Website:
http://www.bm2.m.u-tokyo.ac.jp/

128 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Hagihara H, Shoji H, Hattori S, Sala G, Takamiya Y, Tanaka M, Ihara M, Shibutani M, Hatada I, Hori K, Hoshino M, Nakao A, Mori Y, Okabe S, Matsushita M, ... ... Kasai H, et al. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. Elife. 12. PMID 38529532 DOI: 10.7554/eLife.89376  0.633
2022 Yamaguchi K, Maeda Y, Sawada T, Iino Y, Tajiri M, Nakazato R, Ishii S, Kasai H, Yagishita S. A behavioural correlate of the synaptic eligibility trace in the nucleus accumbens. Scientific Reports. 12: 1921. PMID 35121769 DOI: 10.1038/s41598-022-05637-6  0.5
2021 Ucar H, Watanabe S, Noguchi J, Morimoto Y, Iino Y, Yagishita S, Takahashi N, Kasai H. Mechanical actions of dendritic-spine enlargement on presynaptic exocytosis. Nature. PMID 34819666 DOI: 10.1038/s41586-021-04125-7  0.557
2021 Urakubo H, Yagishita S, Kasai H, Kubota Y, Ishii S. The critical balance between dopamine D2 receptor and RGS for the sensitive detection of a transient decay in dopamine signal. Plos Computational Biology. 17: e1009364. PMID 34591840 DOI: 10.1371/journal.pcbi.1009364  0.437
2021 Kasai H, Ziv NE, Okazaki H, Yagishita S, Toyoizumi T. Spine dynamics in the brain, mental disorders and artificial neural networks. Nature Reviews. Neuroscience. PMID 34050339 DOI: 10.1038/s41583-021-00467-3  0.458
2020 Fujita Y, Yagishita S, Kasai H, Ishii S. Computational Characteristics of the Striatal Dopamine System Described by Reinforcement Learning With Fast Generalization. Frontiers in Computational Neuroscience. 14: 66. PMID 32774245 DOI: 10.3389/Fncom.2020.00066  0.502
2020 Urakubo H, Yagishita S, Kasai H, Ishii S. Signaling models for dopamine-dependent temporal contiguity in striatal synaptic plasticity. Plos Computational Biology. 16: e1008078. PMID 32701987 DOI: 10.1371/Journal.Pcbi.1008078  0.568
2020 Iino Y, Sawada T, Yamaguchi K, Tajiri M, Ishii S, Kasai H, Yagishita S. Dopamine D2 receptors in discrimination learning and spine enlargement. Nature. 579: 555-560. PMID 32214250 DOI: 10.1038/S41586-020-2115-1  0.497
2020 Seaton G, Hodges G, de Haan A, Grewal A, Pandey A, Kasai H, Fox K. Dual-component structural plasticity mediated by αCaMKII-autophosphorylation on basal dendrites of cortical layer 2/3 neurones. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32001612 DOI: 10.1523/Jneurosci.2297-19.2020  0.383
2020 Urakubo H, Yagishita S, Kasai H, Ishii S. Detailed description of D1 and D2 RP models. Plos Computational Biology. DOI: 10.1371/Journal.Pcbi.1008078.S004  0.447
2019 Noguchi J, Nagaoka A, Hayama T, Ucar H, Yagishita S, Takahashi N, Kasai H. Bidirectional in vivo structural dendritic spine plasticity revealed by two-photon glutamate uncaging in the mouse neocortex. Scientific Reports. 9: 13922. PMID 31558759 DOI: 10.1038/S41598-019-50445-0  0.59
2019 Humble J, Hiratsuka K, Kasai H, Toyoizumi T. Intrinsic Spine Dynamics Are Critical for Recurrent Network Learning in Models With and Without Autism Spectrum Disorder. Frontiers in Computational Neuroscience. 13: 38. PMID 31263407 DOI: 10.3389/Fncom.2019.00038  0.348
2019 Park I, Kim HJ, Kim Y, Hwang HS, Kasai H, Kim JH, Park JW. Nanoscale imaging reveals miRNA-mediated control of functional states of dendritic spines. Proceedings of the National Academy of Sciences of the United States of America. PMID 31019087 DOI: 10.1073/Pnas.1819374116  0.311
2018 Tse A, Lee AK, Takahashi N, Gong A, Kasai H, Tse FW. Strong stimulation triggers full fusion exocytosis and very slow endocytosis of the small dense core granules in carotid glomus cells. Journal of Neurogenetics. 32: 267-278. PMID 30484390 DOI: 10.1080/01677063.2018.1497629  0.401
2018 Ishii K, Nagaoka A, Kishida Y, Okazaki H, Yagishita S, Ucar H, Takahashi N, Saito N, Kasai H. Volume Dynamics of Dendritic Spines in the Neocortex of Wild-Type and KO Mice. Eneuro. 5. PMID 30417082 DOI: 10.1523/ENEURO.0282-18.2018  0.501
2018 Tainaka K, Murakami TC, Susaki EA, Shimizu C, Saito R, Takahashi K, Hayashi-Takagi A, Sekiya H, Arima Y, Nojima S, Ikemura M, Ushiku T, Shimizu Y, Murakami M, Tanaka KF, ... ... Kasai H, et al. Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents. Cell Reports. 24: 2196-2210.e9. PMID 30134179 DOI: 10.1016/J.Celrep.2018.07.056  0.653
2018 Okazaki H, Hayashi-Takagi A, Nagaoka A, Negishi M, Ucar H, Yagishita S, Ishii K, Fox K, Toyoizumi T, Kasai H. Calcineurin knockout mice show a selective loss of small spines. Neuroscience Letters. PMID 29427598 DOI: 10.1016/J.Neulet.2018.02.006  0.73
2017 Dagliyan O, Karginov AV, Yagishita S, Gale ME, Wang H, DerMardirossian C, Wells CM, Dokholyan NV, Kasai H, Hahn KM. Engineering Pak1 allosteric switches. Acs Synthetic Biology. PMID 28365983 DOI: 10.1021/Acssynbio.6B00359  0.754
2016 Noguchi J, Hayama T, Watanabe S, Ucar H, Yagishita S, Takahashi N, Kasai H. State-dependent diffusion of actin-depolymerizing factor/cofilin underlies the enlargement and shrinkage of dendritic spines. Scientific Reports. 6: 32897. PMID 27595610 DOI: 10.1038/Srep32897  0.556
2016 Miyazaki J, Iida T, Tanaka S, Hayashi-Takagi A, Kasai H, Okabe S, Kobayashi T. Fast 3D visualization of endogenous brain signals with high-sensitivity laser scanning photothermal microscopy. Biomedical Optics Express. 7: 1702-10. PMID 27231615 DOI: 10.1364/Boe.7.001702  0.672
2016 Nagaoka A, Takehara H, Hayashi-Takagi A, Noguchi J, Ishii K, Shirai F, Yagishita S, Akagi T, Ichiki T, Kasai H. Abnormal intrinsic dynamics of dendritic spines in a fragile X syndrome mouse model in vivo. Scientific Reports. 6: 26651. PMID 27221801 DOI: 10.1038/Srep26651  0.746
2015 Takahashi N, Sawada W, Noguchi J, Watanabe S, Ucar H, Hayashi-Takagi A, Yagishita S, Ohno M, Tokumaru H, Kasai H. Two-photon fluorescence lifetime imaging of primed SNARE complexes in presynaptic terminals and β cells. Nature Communications. 6: 8531. PMID 26439845 DOI: 10.1038/Ncomms9531  0.751
2015 Hayashi-Takagi A, Yagishita S, Nakamura M, Shirai F, Wu YI, Loshbaugh AL, Kuhlman B, Hahn KM, Kasai H. Labelling and optical erasure of synaptic memory traces in the motor cortex. Nature. 525: 333-8. PMID 26352471 DOI: 10.1038/Nature15257  0.755
2015 Takahashi N, Sawada W, Noguchi J, Watanabe S, Ucar H, Hayashi-Takagi A, Yagishita S, Ohno M, Tokumaru H, Kasai H. Two-photon fluorescence lifetime imaging of primed SNARE complexes in presynaptic terminals and β cells Nature Communications. 6. DOI: 10.1038/ncomms9531  0.714
2014 Takehara H, Nagaoka A, Noguchi J, Akagi T, Kasai H, Ichiki T. Lab-on-a-brain: implantable micro-optical fluidic devices for neural cell analysis in vivo. Scientific Reports. 4: 6721. PMID 25335545 DOI: 10.1038/Srep06721  0.323
2014 Yagishita S, Hayashi-Takagi A, Ellis-Davies GC, Urakubo H, Ishii S, Kasai H. A critical time window for dopamine actions on the structural plasticity of dendritic spines. Science (New York, N.Y.). 345: 1616-20. PMID 25258080 DOI: 10.1126/Science.1255514  0.745
2014 Miyazaki J, Tsurui H, Hayashi-Takagi A, Kasai H, Kobayashi T. Sub-diffraction resolution pump-probe microscopy with shot-noise limited sensitivity using laser diodes. Optics Express. 22: 9024-32. PMID 24787791 DOI: 10.1364/Oe.22.009024  0.673
2014 Hayashi-Takagi A, Araki Y, Nakamura M, Vollrath B, Duron SG, Yan Z, Kasai H, Huganir RL, Campbell DA, Sawa A. PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence. Proceedings of the National Academy of Sciences of the United States of America. 111: 6461-6. PMID 24706880 DOI: 10.1073/Pnas.1321109111  0.689
2013 Asrican B, Augustine GJ, Berglund K, Chen S, Chow N, Deisseroth K, Feng G, Gloss B, Hira R, Hoffmann C, Kasai H, Katarya M, Kim J, Kudolo J, Lee LM, et al. Next-generation transgenic mice for optogenetic analysis of neural circuits. Frontiers in Neural Circuits. 7: 160. PMID 24324405 DOI: 10.3389/Fncir.2013.00160  0.695
2013 Hayama T, Noguchi J, Watanabe S, Takahashi N, Hayashi-Takagi A, Ellis-Davies GC, Matsuzaki M, Kasai H. GABA promotes the competitive selection of dendritic spines by controlling local Ca2+ signaling. Nature Neuroscience. 16: 1409-16. PMID 23974706 DOI: 10.1038/Nn.3496  0.811
2013 Hira R, Ohkubo F, Tanaka YR, Masamizu Y, Augustine GJ, Kasai H, Matsuzaki M. In vivo optogenetic tracing of functional corticocortical connections between motor forelimb areas. Frontiers in Neural Circuits. 7: 55. PMID 23554588 DOI: 10.3389/Fncir.2013.00055  0.712
2013 Lam PP, Ohno M, Dolai S, He Y, Qin T, Liang T, Zhu D, Kang Y, Liu Y, Kauppi M, Xie L, Wan WC, Bin NR, Sugita S, Olkkonen VM, ... ... Kasai H, et al. Munc18b is a major mediator of insulin exocytosis in rat pancreatic β-cells. Diabetes. 62: 2416-28. PMID 23423569 DOI: 10.2337/Db12-1380  0.304
2013 Hira R, Ohkubo F, Ozawa K, Isomura Y, Kitamura K, Kano M, Kasai H, Matsuzaki M. Spatiotemporal dynamics of functional clusters of neurons in the mouse motor cortex during a voluntary movement. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 1377-90. PMID 23345214 DOI: 10.1523/Jneurosci.2550-12.2013  0.682
2012 Kasai H, Takahashi N, Tokumaru H. Distinct initial SNARE configurations underlying the diversity of exocytosis. Physiological Reviews. 92: 1915-64. PMID 23073634 DOI: 10.1152/Physrev.00007.2012  0.352
2012 Ogata S, Miki T, Seino S, Tamai S, Kasai H, Nemoto T. A novel function of Noc2 in agonist-induced intracellular Ca2+ increase during zymogen-granule exocytosis in pancreatic acinar cells. Plos One. 7: e37048. PMID 22615885 DOI: 10.1371/Journal.Pone.0037048  0.378
2012 Hira R, Ohkubo F, Ozawa K, Isomura Y, Kitamura K, Kano M, Kasai H, Matsuzaki M. 2SH-05 Two-photon imaging of the mouse motor cortex during voluntary skilled movement(2SH Star of life shined by frontier microscopies,Symposium,The 50th Annual Meeting of the Biophysical Society of Japan) Seibutsu Butsuri. 52: S16. DOI: 10.2142/Biophys.52.S16_5  0.678
2011 Matsuzaki M, Ellis-Davies GC, Kanemoto Y, Kasai H. Simultaneous two-photon activation of presynaptic cells and calcium imaging in postsynaptic dendritic spines. Neural Systems & Circuits. 1: 2. PMID 22330013 DOI: 10.1186/2042-1001-1-2  0.688
2011 Ako R, Wakimoto M, Ebisu H, Tanno K, Hira R, Kasai H, Matsuzaki M, Kawasaki H. Simultaneous visualization of multiple neuronal properties with single-cell resolution in the living rodent brain. Molecular and Cellular Neurosciences. 48: 246-57. PMID 21884798 DOI: 10.1016/J.Mcn.2011.08.005  0.656
2011 Kanemoto Y, Matsuzaki M, Morita S, Hayama T, Noguchi J, Senda N, Momotake A, Arai T, Kasai H. Spatial distributions of GABA receptors and local inhibition of Ca2+ transients studied with GABA uncaging in the dendrites of CA1 pyramidal neurons. Plos One. 6: e22652. PMID 21799926 DOI: 10.1371/Journal.Pone.0022652  0.662
2011 Matsuzaki M, Kasai H. Two-photon uncaging microscopy. Cold Spring Harbor Protocols. 2011: pdb.prot5620. PMID 21536760 DOI: 10.1101/Pdb.Prot5620  0.662
2011 Noguchi J, Nagaoka A, Watanabe S, Ellis-Davies GC, Kitamura K, Kano M, Matsuzaki M, Kasai H. In vivo two-photon uncaging of glutamate revealing the structure-function relationships of dendritic spines in the neocortex of adult mice. The Journal of Physiology. 589: 2447-57. PMID 21486811 DOI: 10.1016/J.Neures.2011.07.891  0.747
2011 Ako R, Ebisu H, Wakimoto M, Tanno K, Hira R, Kasai H, Matsuzaki M, Kawasaki H. A rapid genetic strategy for multiple-gene, single-neuron labeling in the living rodent brain Neuroscience Research. 71: e412. DOI: 10.1016/J.Neures.2011.07.1807  0.621
2011 Ohkubo F, Hira R, Kasai H, Matsuzaki M. Optogenetic functional tracing for identifying functional connections between cortical motor areas in vivo Neuroscience Research. 71: e312. DOI: 10.1016/J.Neures.2011.07.1362  0.609
2010 Kasai H, Hayama T, Ishikawa M, Watanabe S, Yagishita S, Noguchi J. Learning rules and persistence of dendritic spines. The European Journal of Neuroscience. 32: 241-9. PMID 20646057 DOI: 10.1111/J.1460-9568.2010.07344.X  0.535
2010 Takahashi N, Hatakeyama H, Okado H, Noguchi J, Ohno M, Kasai H. SNARE conformational changes that prepare vesicles for exocytosis. Cell Metabolism. 12: 19-29. PMID 20620992 DOI: 10.1016/J.Cmet.2010.05.013  0.376
2010 Matsuzaki M, Hayama T, Kasai H, Ellis-Davies GC. Two-photon uncaging of gamma-aminobutyric acid in intact brain tissue. Nature Chemical Biology. 6: 255-7. PMID 20173751 DOI: 10.1038/Nchembio.321  0.638
2010 Kasai H, Fukuda M, Watanabe S, Hayashi-Takagi A, Noguchi J. Structural dynamics of dendritic spines in memory and cognition. Trends in Neurosciences. 33: 121-9. PMID 20138375 DOI: 10.1016/J.Tins.2010.01.001  0.693
2010 Kantevari S, Matsuzaki M, Kanemoto Y, Kasai H, Ellis-Davies GC. Two-color, two-photon uncaging of glutamate and GABA. Nature Methods. 7: 123-5. PMID 20037590 DOI: 10.1038/Nmeth.1413  0.672
2010 Obi N, Momotake A, Kanemoto Y, Matsuzaki M, Kasai H, Arai T. 1-Acyl-5-methoxy-8-nitro-1,2-dihydroquinoline: a biologically useful photolabile precursor of carboxylic acids Tetrahedron Letters. 51: 1642-1647. DOI: 10.1016/J.Tetlet.2009.12.081  0.645
2010 Matsuzaki M, Ellis-Davies GC, Hayama T, Kanemoto Y, Kasai H. Optical stimulation of synapses and neurons Neuroscience Research. 68: e26. DOI: 10.1016/J.Neures.2010.07.355  0.649
2010 Hayama T, Kanemoto Y, Matsuzaki M, Ellis-Davies GC, Kasai H. GABA dependence of glutamate-mediated shrinkage and elimination of dendritic spines revealed with two-color uncaging of glutamate and GABA Neuroscience Research. 68: e340. DOI: 10.1016/J.Neures.2010.07.1504  0.625
2010 Kanemoto Y, Matsuzaki M, Kasai H. P2-b19Two-color, two-photon uncaging of glutamate and GABA Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.1033  0.61
2009 Hira R, Honkura N, Noguchi J, Maruyama Y, Augustine GJ, Kasai H, Matsuzaki M. Transcranial optogenetic stimulation for functional mapping of the motor cortex. Journal of Neuroscience Methods. 179: 258-63. PMID 19428535 DOI: 10.1016/J.Jneumeth.2009.02.001  0.704
2009 Morita S, Yasumatsu N, Noguchi J, Kasai H. Generation, elimination and weight fluctuations of synapses in the cerebral cortex Communicative and Integrative Biology. 2: 526-529. DOI: 10.4161/Cib.2.6.9564  0.351
2009 Kasai H, Kanemoto Y, Matsuzaki M, Ellis-Davis G, Momotake A, Arai T, Hahn K, Wu Y, Ishikawa M, Noguchi J, Hayama T, Watanabe S, Morita S. Exploration of two-photon photostimulation for neuroscience Neuroscience Research. 65: S3. DOI: 10.1016/J.Neures.2009.09.1479  0.599
2009 Hira R, Okubo F, Honkura N, Noguchi J, Maruyama Y, Augustine GJ, Kasai H, Matsuzaki M. Transcranial optogenetic stimulation for mapping of the motor cortex Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.1099  0.681
2008 Yasumatsu N, Matsuzaki M, Miyazaki T, Noguchi J, Kasai H. Principles of long-term dynamics of dendritic spines. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13592-608. PMID 19074033 DOI: 10.1523/Jneurosci.0603-08.2008  0.674
2008 Honkura N, Matsuzaki M, Noguchi J, Ellis-Davies GC, Kasai H. The subspine organization of actin fibers regulates the structure and plasticity of dendritic spines. Neuron. 57: 719-29. PMID 18341992 DOI: 10.1016/J.Neuron.2008.01.013  0.663
2008 Tanaka J, Horiike Y, Matsuzaki M, Miyazaki T, Ellis-Davies GC, Kasai H. Protein synthesis and neurotrophin-dependent structural plasticity of single dendritic spines. Science (New York, N.Y.). 319: 1683-7. PMID 18309046 DOI: 10.1126/Science.1152864  0.678
2008 Matsuzaki M, Ellis-Davies GC, Kasai H. Three-dimensional mapping of unitary synaptic connections by two-photon macro photolysis of caged glutamate. Journal of Neurophysiology. 99: 1535-44. PMID 18216227 DOI: 10.1152/Jn.01127.2007  0.692
2007 Ellis-Davies GC, Matsuzaki M, Paukert M, Kasai H, Bergles DE. 4-Carboxymethoxy-5,7-dinitroindolinyl-Glu: an improved caged glutamate for expeditious ultraviolet and two-photon photolysis in brain slices. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6601-4. PMID 17581946 DOI: 10.1523/Jneurosci.1519-07.2007  0.65
2007 Hatakeyama H, Takahashi N, Kishimoto T, Nemoto T, Kasai H. Two cAMP-dependent pathways differentially regulate exocytosis of large dense-core and small vesicles in mouse beta-cells. The Journal of Physiology. 582: 1087-98. PMID 17510178 DOI: 10.1113/Jphysiol.2007.135228  0.397
2007 Wang H, Peca J, Matsuzaki M, Matsuzaki K, Noguchi J, Qiu L, Wang D, Zhang F, Boyden E, Deisseroth K, Kasai H, Hall WC, Feng G, Augustine GJ. High-speed mapping of synaptic connectivity using photostimulation in Channelrhodopsin-2 transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 8143-8. PMID 17483470 DOI: 10.1073/Pnas.0700384104  0.734
2007 Takahashi N, Kasai H. Exocytic process analyzed with two-photon excitation imaging in endocrine pancreas. Endocrine Journal. 54: 337-46. PMID 17409577 DOI: 10.1507/Endocrj.Kr-94  0.306
2007 Augustine GJ, Kasai H. Bernard Katz, quantal transmitter release and the foundations of presynaptic physiology. The Journal of Physiology. 578: 623-5. PMID 17068096 DOI: 10.1113/Jphysiol.2006.123224  0.591
2007 Matsuzaki M, Ellis-Davies GC, Kasai H. Synaptic connections to layer 2/3 pyramidal neurons in rat visual cortex revealed by two-photon activation of caged glutamate Neuroscience Research. 58: S155. DOI: 10.1016/J.Neures.2007.06.633  0.669
2007 Noguchi J, Miyazaki T, Nagaoka A, Ellis-Davies GC, Matsuzaki M, Kasai H. Functional mapping of glutamate receptors in dendrites of mouse neocortical neurons in vivo using two-photon microscope Neuroscience Research. 58: S13. DOI: 10.1016/J.Neures.2007.06.072  0.658
2006 Kasai H, Kishimoto T, Nemoto T, Hatakeyama H, Liu TT, Takahashi N. Two-photon excitation imaging of exocytosis and endocytosis and determination of their spatial organization. Advanced Drug Delivery Reviews. 58: 850-77. PMID 16996640 DOI: 10.1016/J.Addr.2006.07.008  0.301
2006 Kishimoto T, Kimura R, Liu TT, Nemoto T, Takahashi N, Kasai H. Vacuolar sequential exocytosis of large dense-core vesicles in adrenal medulla. The Embo Journal. 25: 673-82. PMID 16467850 DOI: 10.1038/Sj.Emboj.7600983  0.327
2006 Hatakeyama H, Kishimoto T, Nemoto T, Kasai H, Takahashi N. Rapid glucose sensing by protein kinase A for insulin exocytosis in mouse pancreatic islets. The Journal of Physiology. 570: 271-82. PMID 16284079 DOI: 10.1113/Jphysiol.2005.096560  0.302
2005 Ohkura M, Matsuzaki M, Kasai H, Imoto K, Nakai J. Genetically encoded bright Ca2+ probe applicable for dynamic Ca2+ imaging of dendritic spines. Analytical Chemistry. 77: 5861-9. PMID 16159115 DOI: 10.1021/Ac0506837  0.661
2005 Kasai H, Hatakeyama H, Kishimoto T, Liu TT, Nemoto T, Takahashi N. A new quantitative (two-photon extracellular polar-tracer imaging-based quantification (TEPIQ)) analysis for diameters of exocytic vesicles and its application to mouse pancreatic islets. The Journal of Physiology. 568: 891-903. PMID 16150799 DOI: 10.1113/Jphysiol.2005.093047  0.308
2005 Kishimoto T, Liu TT, Hatakeyama H, Nemoto T, Takahashi N, Kasai H. Sequential compound exocytosis of large dense-core vesicles in PC12 cells studied with TEPIQ (two-photon extracellular polar-tracer imaging-based quantification) analysis. The Journal of Physiology. 568: 905-15. PMID 16150797 DOI: 10.1113/Jphysiol.2005.094003  0.355
2005 Liu TT, Kishimoto T, Hatakeyama H, Nemoto T, Takahashi N, Kasai H. Exocytosis and endocytosis of small vesicles in PC12 cells studied with TEPIQ (two-photon extracellular polar-tracer imaging-based quantification) analysis. The Journal of Physiology. 568: 917-29. PMID 16150796 DOI: 10.1113/Jphysiol.2005.094011  0.355
2005 Noguchi J, Matsuzaki M, Ellis-Davies GC, Kasai H. Spine-neck geometry determines NMDA receptor-dependent Ca2+ signaling in dendrites. Neuron. 46: 609-22. PMID 15944129 DOI: 10.1016/J.Neuron.2005.03.015  0.699
2005 Hayakawa Y, Nemoto T, Iino M, Kasai H. Rapid Ca2+-dependent increase in oxygen consumption by mitochondria in single mammalian central neurons. Cell Calcium. 37: 359-70. PMID 15755497 DOI: 10.1016/J.Ceca.2004.11.005  0.375
2005 Oshima A, Kojima T, Dejima K, Hisa Y, Kasai H, Nemoto T. Two-photon microscopic analysis of acetylcholine-induced mucus secretion in guinea pig nasal glands. Cell Calcium. 37: 349-57. PMID 15755496 DOI: 10.1016/J.Ceca.2004.12.003  0.388
2005 Tanaka J, Matsuzaki M, Tarusawa E, Momiyama A, Molnar E, Kasai H, Shigemoto R. Number and density of AMPA receptors in single synapses in immature cerebellum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 799-807. PMID 15673659 DOI: 10.1523/Jneurosci.4256-04.2005  0.659
2004 Sakai N, Tsubokawa H, Matsuzaki M, Kajimoto T, Takahashi E, Ren Y, Ohmori S, Shirai Y, Matsubayashi H, Chen J, Duman RS, Kasai H, Saito N. Propagation of gammaPKC translocation along the dendrites of Purkinje cell in gammaPKC-GFP transgenic mice. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 9: 945-57. PMID 15461665 DOI: 10.1111/J.1365-2443.2004.00779.X  0.697
2004 Matsuzaki M, Honkura N, Ellis-Davies GC, Kasai H. Structural basis of long-term potentiation in single dendritic spines. Nature. 429: 761-6. PMID 15190253 DOI: 10.1038/Nature02617  0.69
2004 Takahashi N, Hatakeyama H, Okado H, Miwa A, Kishimoto T, Kojima T, Abe T, Kasai H. Sequential exocytosis of insulin granules is associated with redistribution of SNAP25. The Journal of Cell Biology. 165: 255-62. PMID 15117968 DOI: 10.1083/Jcb.200312033  0.31
2004 Kasai H, Matsuzaki M, Noguchi J, Yasumatsu N, Honkura N. [Structure-stability-function relationships of dendritic spines]. Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. 49: 276-81. PMID 14976742  0.584
2003 Kasai H, Matsuzaki M, Noguchi J, Yasumatsu N, Nakahara H. Structure-stability-function relationships of dendritic spines. Trends in Neurosciences. 26: 360-8. PMID 12850432 DOI: 10.1016/S0166-2236(03)00162-0  0.675
2002 Kasai H, Matsuzaki M, Noguchi J, Yasumatsu N. [Dendritic spine structures and functions]. Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. 22: 159-64. PMID 12451686  0.639
2002 Takahashi N, Nemoto T, Kimura R, Tachikawa A, Miwa A, Okado H, Miyashita Y, Iino M, Kadowaki T, Kasai H. Two-photon excitation imaging of pancreatic islets with various fluorescent probes. Diabetes. 51: S25-8. PMID 11815453 DOI: 10.2337/Diabetes.51.2007.S25  0.664
2002 Nemoto T, Kojima T, Ohshima A, Kasai H. 2N1500 Ca^<2+> dependent exocytosis contorolled by F-actin reorganization revealed by two-photon microscopy and photolysis of caged Ca^<2+> Seibutsu Butsuri. 42: S142. DOI: 10.2142/Biophys.42.S142_2  0.35
2001 Matsuzaki M, Ellis-Davies GC, Nemoto T, Miyashita Y, Iino M, Kasai H. Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons. Nature Neuroscience. 4: 1086-92. PMID 11687814 DOI: 10.1038/Nn736  0.79
2001 Kishimoto T, Liu T, Ninomiya Y, Takagi H, Yoshioka T, Ellis-Davies GCR, Miyashita Y, Kasai H. Ion selectivities of the Ca2+ sensors for exocytosis in rat phaeochromocytoma cells The Journal of Physiology. 533: 627-637. PMID 11410622 DOI: 10.1111/J.1469-7793.2001.T01-1-00627.X  0.65
2001 Nemoto T, Kimura R, Ito K, Tachikawa A, Miyashita Y, Iino M, Kasai H. Sequential-replenishment mechanism of exocytosis in pancreatic acini. Nature Cell Biology. 3: 253-8. PMID 11231574 DOI: 10.1038/35060042  0.673
2000 Maeda H, Ellis-Davies GC, Ito K, Miyashita Y, Kasai H. Supralinear Ca2+ signaling by cooperative and mobile Ca2+ buffering in Purkinje neurons. Neuron. 24: 989-1002. PMID 10624961 DOI: 10.1016/S0896-6273(00)81045-4  0.684
1999 Ito K, Miyashita Y, Kasai H. Kinetic control of multiple forms of Ca(2+) spikes by inositol trisphosphate in pancreatic acinar cells. The Journal of Cell Biology. 146: 405-13. PMID 10427093 DOI: 10.1083/Jcb.146.2.405  0.685
1999 Kasai H, Takahashi N. Multiple kinetic components and the Ca2+ requirements of exocytosis. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 354: 331-5. PMID 10212481 DOI: 10.1098/Rstb.1999.0384  0.391
1999 Kasai H. Comparative biology of Ca2+-dependent exocytosis: implications of kinetic diversity for secretory function. Trends in Neurosciences. 22: 88-93. PMID 10092049 DOI: 10.1016/S0166-2236(98)01293-4  0.378
1999 Kasai H, Kishimoto T, Liu TT, Miyashita Y, Podini P, Grohovaz F, Meldolesi J. Multiple and diverse forms of regulated exocytosis in wild-type and defective PC12 cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 945-9. PMID 9927673 DOI: 10.1073/Pnas.96.3.945  0.67
1999 Takahashi N, Kadowaki T, Yazaki Y, Ellis-Davies GC, Miyashita Y, Kasai H. Post-priming actions of ATP on Ca2+-dependent exocytosis in pancreatic beta cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 760-5. PMID 9892707 DOI: 10.1073/Pnas.96.2.760  0.657
1998 Maeda H, Ito K, Tachikawa A, Ellis-Davies G, Miyashita Y, Kasai H. High-affinity Ca2+ buffers play a non-linear Ca2+ signaling in Purkinje neurons Neuroscience Research. 31: S120. DOI: 10.1016/S0168-0102(98)81989-5  0.685
1998 Kasai H, Nemoto T, Hayakawa Y, Takahashi N, Maeda H, Tachikawa A, Matsuzaki M, Iino M, Miyashita Y. Multiphoton excitation tomography in cell biology Neuroscience Research. 31: S31. DOI: 10.1016/S0168-0102(98)81617-9  0.736
1997 Takahashi N, Kadowaki T, Yazaki Y, Miyashita Y, Kasai H. Multiple exocytotic pathways in pancreatic beta cells. The Journal of Cell Biology. 138: 55-64. PMID 9214381 DOI: 10.1083/Jcb.138.1.55  0.672
1997 Kasai H, Mori A, Takahashi T, Miyashita Y. Quantal properties of single glutamatergic synaptic boutons in thin slices from rat neostriatum. Annals of the New York Academy of Sciences. 707: 458-9. PMID 9137594 DOI: 10.1111/J.1749-6632.1993.Tb38097.X  0.667
1997 Ninomiya Y, Kishimoto T, Yamazawa T, Ikeda H, Miyashita Y, Kasai H. Kinetic diversity in the fusion of exocytotic vesicles. The Embo Journal. 16: 929-34. PMID 9118954 DOI: 10.1093/Emboj/16.5.929  0.696
1997 Ito K, Miyashita Y, Kasai H. Micromolar and submicromolar Ca2+ spikes regulating distinct cellular functions in pancreatic acinar cells Embo Journal. 16: 242-251. PMID 9029145 DOI: 10.1093/Emboj/16.2.242  0.687
1997 Sjödin L, Ito K, Miyashita Y, Kasai H. Cytoplasmic Ca2+ gradients evoked by acetylcholine and peptides in pancreatic acinar cells of the guinea-pig. Pflugers Archiv : European Journal of Physiology. 433: 397-402. PMID 9000418 DOI: 10.1007/S004240050294  0.68
1996 Kasai H, Takagi H, Ninomiya Y, Kishimoto T, Ito K, Yoshida A, Yoshioka T, Miyashita Y. Two components of exocytosis and endocytosis in phaeochromocytoma cells studied using caged Ca2+ compounds. The Journal of Physiology. 53-65. PMID 8814606 DOI: 10.1113/Jphysiol.1996.Sp021475  0.698
1996 Ninomiya Y, Kishimoto T, Miyashita Y, Kasai H. Ca2+-dependent exocytotic pathways in Chinese hamster ovary fibroblasts revealed by a caged-Ca2+ compound. The Journal of Biological Chemistry. 271: 17751-4. PMID 8663485 DOI: 10.1074/Jbc.271.30.17751  0.694
1996 Ninomiya Y, Kishimoto T, Miyashita Y, Kasai H. 217 Distinct rate constants of dense-core vesicle fusion in pc12 cells and chromaffin cells revealed with a carbon-fiber electrode and caged-Ca2+ compounds Neuroscience Research. 25: S34. DOI: 10.1016/0168-0102(96)88646-9  0.656
1996 Kishimoto T, Ninomiya Y, Miyashita Y, Kasai H. 216 Direct characterization of Ca2+-dependent events of small-clear vesicle fusion in single pc12 cells Neuroscience Research. 25: S34. DOI: 10.1016/0168-0102(96)88645-7  0.688
1996 Maeda H, Ito K, Miyashita Y, Kasai H. 116 Micromolar Ca2+ gradients in the dendrites of cultured cerebellar purkinje cells Neuroscience Research. 25: S22. DOI: 10.1016/0168-0102(96)88611-1  0.685
1996 Ito K, Miyashita Y, Kasai H. 115 Four-wavelength ratiometric Ca2+ imaging using btc and fura-2 simultaneously Neuroscience Research. 25: S22. DOI: 10.1016/0168-0102(96)88610-X  0.669
1995 Mori A, Takahashi T, Miyashita Y, Kasai H. Quantal properties of H-type glutamatergic synaptic input to the striatal medium spiny neurons. Brain Research. 654: 177-9. PMID 7982094 DOI: 10.1016/0006-8993(94)91587-3  0.67
1994 Mori A, Takahashi T, Miyashita Y, Kasai H. Two distinct glutamatergic synaptic inputs to striatal medium spiny neurones of neonatal rats and paired-pulse depression. The Journal of Physiology. 476: 217-28. PMID 8046639 DOI: 10.1113/Jphysiol.1994.Sp020125  0.672
1994 Mori A, Takahashi T, Miyashita Y, Kasai H. Quantal properties of S-type glutamatergic synaptic input to the striatal medium spiny neuron from neonate rat. Neuroscience Letters. 169: 199-202. PMID 7914014 DOI: 10.1016/0304-3940(94)90391-3  0.7
1994 Kasai H, Petersen OH. Spatial dynamics of second messengers: IP3 and cAMP as long-range and associative messengers. Trends in Neurosciences. 17: 95-101. PMID 7515531 DOI: 10.1016/0166-2236(94)90112-0  0.358
1994 Takagi H, Ninomiya Y, Ito K, Yoshida A, Yoshioka T, Miyashita Y, Kasai H. Conserved calcium- and time-dependence of exocytosis among different secretory cells revealed by rapid photolysis of caged compounds Neuroscience Research Supplements. 19: S35. DOI: 10.1016/0921-8696(94)92358-2  0.629
1994 Iino M, Kasai H, Yamazawa T. Visualization of neural control of intracellular Ca2+ concentration in single vascular smooth muscle cells in situ. The Embo Journal. 13: 5026-5031. DOI: 10.1002/J.1460-2075.1994.Tb06831.X  0.363
1993 Kasai H, Li YX, Miyashita Y. Subcellular distribution of Ca2+ release channels underlying Ca2+ waves and oscillations in exocrine pancreas Cell. 74: 669-677. PMID 8395348 DOI: 10.1016/0092-8674(93)90514-Q  0.679
1993 Kasai H. Cytosolic Ca2+ gradients, Ca2+ binding proteins and synaptic plasticity. Neuroscience Research. 16: 1-7. PMID 8251011 DOI: 10.1016/0168-0102(93)90002-8  0.431
1993 Kasai H, Li YX, Ishihara I, Hori A, Yamazawa T, Miyashita Y. 211 Direct visualization and physiological characterization of presynaptic terminals in cultured mammalian central neurons Neuroscience Research Supplements. 18: S30. DOI: 10.1016/S0921-8696(05)80753-4  0.645
1993 Iino M, Yamazawa T, Miyashita Y, Endo M, Kasai H. Critical intracellular Ca2+ concentration for all-or-none Ca2+ spiking in single smooth muscle cells. The Embo Journal. 12: 5287-5291. DOI: 10.1002/J.1460-2075.1993.Tb06224.X  0.681
1993 Maruyama Y, Inooka G, Li Y, Miyashita Y, Kasai H. Agonist-induced localized Ca2+ spikes directly triggering exocytotic secretion in exocrine pancreas. The Embo Journal. 12: 3017-3022. DOI: 10.1002/J.1460-2075.1993.Tb05970.X  0.682
1992 Kasai H, Neher E. Dihydropyridine-sensitive and omega-conotoxin-sensitive calcium channels in a mammalian neuroblastoma-glioma cell line. The Journal of Physiology. 448: 161-88. PMID 1375634 DOI: 10.1113/Jphysiol.1992.Sp019035  0.542
1992 Kasai H. Voltage- and time-dependent inhibition of neuronal calcium channels by a GTP-binding protein in a mammalian cell line. The Journal of Physiology. 448: 189-209. PMID 1350637 DOI: 10.1113/Jphysiol.1992.Sp019036  0.313
1991 Kasai H. Tonic inhibition and rebound facilitation of a neuronal calcium channel by a GTP-binding protein. Proceedings of the National Academy of Sciences of the United States of America. 88: 8855-8859. PMID 1656456 DOI: 10.1073/Pnas.88.19.8855  0.338
1991 Mori A, Takahashi T, Miyashita Y, Kasai H. Patch-clamp analysis of glutamatergic synaptic transmission in thin slices of the basal ganglia Neuroscience Research Supplements. 16: 25. DOI: 10.1016/0921-8696(91)90710-5  0.675
1990 Kasai H, Augustine GJ. Cytosolic Ca2+ gradients triggering unidirectional fluid secretion from exocrine pancreas. Nature. 348: 735-8. PMID 1701852 DOI: 10.1038/348735A0  0.587
1989 Kasai H, Aosaki T. Modulation of Ca-channel current by an adenosine analog mediated by a GTP-binding protein in chick sensory neurons. PflüGers Archiv: European Journal of Physiology. 414: 145-149. PMID 2547194 DOI: 10.1007/Bf00580956  0.372
1988 Kasai H, Aosaki T. Divalent cation dependent inactivation of the high-voltage-activated Ca-channel current in chick sensory neurons. PflüGers Archiv: European Journal of Physiology. 411: 695-697. PMID 2457872 DOI: 10.1007/Bf00580869  0.325
1987 Kasai H, Aosaki T, Fukuda J. Presynaptic Ca-antagonist ω-conotoxin irreversibly blocks N-type Ca-channels in chick sensory neurons Neuroscience Research. 4: 228-235. DOI: 10.1016/S0921-8696(87)80021-X  0.371
1987 Kasai H, Aosaki T. Properties of the N- and L-type Ca-currents in chick DRG neurons studied using the whole-cell clamp method Neuroscience Research Supplements. 5. DOI: 10.1016/0921-8696(87)90215-5  0.345
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