| Year |
Citation |
Score |
| 2022 |
Eskandari R, Kim N, Mamakhanyan A, Saoi M, Zhang G, Berisaj M, Granlund KL, Poot AJ, Cross J, Thompson CB, Keshari KR. Hyperpolarized [5-C,4,4-H,5-N]-L-glutamine provides a means of annotating in vivo metabolic utilization of glutamine. Proceedings of the National Academy of Sciences of the United States of America. 119: e2120595119. PMID 35512101 DOI: 10.1073/pnas.2120595119 |
0.542 |
|
| 2021 |
Zhu J, Schwörer S, Berisa M, Kyung YJ, Ryu KW, Yi J, Jiang X, Cross JR, Thompson CB. Mitochondrial NADP(H) generation is essential for proline biosynthesis. Science (New York, N.Y.). PMID 33888598 DOI: 10.1126/science.abd5491 |
0.589 |
|
| 2020 |
Pavlova NN, King B, Josselsohn RH, Violante S, Macera VL, Vardhana SA, Cross JR, Thompson CB. Translation in amino acid-poor environments is limited by tRNA charging. Elife. 9. PMID 33289483 DOI: 10.7554/eLife.62307 |
0.564 |
|
| 2020 |
King B, Araki J, Palm W, Thompson CB. Yap/Taz promote the scavenging of extracellular nutrients through macropinocytosis. Genes & Development. PMID 32912902 DOI: 10.1101/Gad.340661.120 |
0.448 |
|
| 2020 |
Vardhana SA, Hwee MA, Berisa M, Wells DK, Yost KE, King B, Smith M, Herrera PS, Chang HY, Satpathy AT, van den Brink MRM, Cross JR, Thompson CB. Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen. Nature Immunology. PMID 32661364 DOI: 10.1038/S41590-020-0725-2 |
0.635 |
|
| 2020 |
Schwörer S, Berisa M, Violante S, Qin W, Zhu J, Hendrickson RC, Cross JR, Thompson CB. Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress. The Embo Journal. e103334. PMID 32134147 DOI: 10.15252/Embj.2019103334 |
0.62 |
|
| 2020 |
Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, Zhou Y, Liu L, Vanharanta S, Graves EE, Rankin EB, Curtis C, Massague J, Rabinowitz JD, Thompson CB, et al. Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Molecular Cancer Research : McR. PMID 31941752 DOI: 10.1158/1541-7786.Mcr-19-0606 |
0.337 |
|
| 2020 |
Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, Zhou Y, Liu L, Vanharanta S, Graves EE, Rankin EB, Curtis C, Massague J, Rabinowitz JD, Thompson CB, et al. Abstract 5713: Reprogramming of serine metabolism during breast cancer progression Cancer Research. 80: 5713-5713. DOI: 10.1158/1538-7445.Am2020-5713 |
0.357 |
|
| 2019 |
Thompson CB, Bielska AA. Growth Factors Stimulate Anabolic Metabolism by Directing Nutrient Uptake. The Journal of Biological Chemistry. PMID 31628187 DOI: 10.1074/Jbc.Aw119.008146 |
0.363 |
|
| 2019 |
Zhu J, Berisa M, Schwörer S, Qin W, Cross JR, Thompson CB. Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation. Cell Metabolism. PMID 31607565 DOI: 10.1016/J.Cmet.2019.09.009 |
0.668 |
|
| 2019 |
Morris JP, Yashinskie JJ, Koche R, Chandwani R, Tian S, Chen CC, Baslan T, Marinkovic ZS, Sánchez-Rivera FJ, Leach SD, Carmona-Fontaine C, Thompson CB, Finley LWS, Lowe SW. α-Ketoglutarate links p53 to cell fate during tumour suppression. Nature. PMID 31534224 DOI: 10.1038/S41586-019-1577-5 |
0.399 |
|
| 2019 |
Schvartzman JM, Reuter VP, Koche RP, Thompson CB. 2-hydroxyglutarate inhibits MyoD-mediated differentiation by preventing H3K9 demethylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31182575 DOI: 10.1073/Pnas.1817662116 |
0.791 |
|
| 2019 |
Zhu J, Thompson CB. Metabolic regulation of cell growth and proliferation. Nature Reviews. Molecular Cell Biology. PMID 30976106 DOI: 10.1038/S41580-019-0123-5 |
0.4 |
|
| 2019 |
Schwörer S, Vardhana SA, Thompson CB. Cancer Metabolism Drives a Stromal Regenerative Response. Cell Metabolism. PMID 30773467 DOI: 10.1016/J.Cmet.2019.01.015 |
0.389 |
|
| 2018 |
Gao M, Yi J, Zhu J, Minikes AM, Monian P, Thompson CB, Jiang X. Role of Mitochondria in Ferroptosis. Molecular Cell. PMID 30581146 DOI: 10.1016/J.Molcel.2018.10.042 |
0.357 |
|
| 2018 |
McKenney AS, Lau AN, Somasundara AVH, Spitzer B, Intlekofer AM, Ahn J, Shank K, Rapaport FT, Patel MA, Papalexi E, Shih AH, Chiu A, Freinkman E, Akbay EA, Steadman M, ... ... Thompson CB, et al. JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition. The Journal of Clinical Investigation. PMID 30222137 DOI: 10.1172/Jci124920 |
0.508 |
|
| 2018 |
Intlekofer AM, Shih AH, Wang B, Nazir A, Rustenburg AS, Albanese SK, Patel M, Famulare C, Correa FM, Takemoto N, Durani V, Liu H, Taylor J, Farnoud N, Papaemmanuil E, ... ... Thompson CB, et al. Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations. Nature. PMID 29950729 DOI: 10.1038/S41586-018-0251-7 |
0.583 |
|
| 2018 |
Redelman-Sidi G, Binyamin A, Gaeta I, Palm W, Thompson CB, Romesser PB, Lowe SW, Bagul M, Doench JG, Root DE, Glickman MS. The Canonical Wnt Pathway Drives Macropinocytosis in Cancer. Cancer Research. PMID 29871936 DOI: 10.1158/0008-5472.Can-17-3199 |
0.353 |
|
| 2018 |
Schvartzman JM, Thompson CB, Finley LWS. Metabolic regulation of chromatin modifications and gene expression. The Journal of Cell Biology. PMID 29760106 DOI: 10.1083/Jcb.201803061 |
0.799 |
|
| 2018 |
Finley LWS, Vardhana SA, Carey BW, Alonso-Curbelo D, Koche R, Chen Y, Wen D, King B, Radler MR, Rafii S, Lowe SW, Allis CD, Thompson CB. Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity. Nature Cell Biology. PMID 29662175 DOI: 10.1038/S41556-018-0086-3 |
0.325 |
|
| 2018 |
Prabakaran T, Bodda C, Krapp C, Zhang BC, Christensen MH, Sun C, Reinert L, Cai Y, Jensen SB, Skouboe MK, Nyengaard JR, Thompson CB, Lebbink RJ, Sen GC, van Loo G, et al. Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1. The Embo Journal. PMID 29496741 DOI: 10.15252/Embj.201797858 |
0.317 |
|
| 2018 |
McKenney AS, Lau AN, Somasundara AVH, Spitzer B, Intlekofer AM, Ahn J, Shank K, Rapaport FT, Patel MA, Papalexi E, Shih AH, Chiu A, Freinkman E, Akbay EA, Steadman M, ... ... Thompson CB, et al. JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition. The Journal of Clinical Investigation. PMID 29355841 DOI: 10.1172/Jci94516 |
0.373 |
|
| 2018 |
Pavlova NN, Hui S, Ghergurovich JM, Fan J, Intlekofer AM, White RM, Rabinowitz JD, Thompson CB, Zhang J. As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid. Cell Metabolism. PMID 29337136 DOI: 10.1016/J.Cmet.2017.12.006 |
0.385 |
|
| 2017 |
Turcan S, Makarov V, Taranda J, Wang Y, Fabius AWM, Wu W, Zheng Y, El-Amine N, Haddock S, Nanjangud G, LeKaye HC, Brennan C, Cross J, Huse JT, Kelleher NL, ... ... Thompson CB, et al. Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence. Nature Genetics. PMID 29180699 DOI: 10.1038/S41588-017-0001-Z |
0.603 |
|
| 2017 |
Salamanca-Cardona L, Shah H, Poot AJ, Correa FM, Di Gialleonardo V, Lui H, Miloushev VZ, Granlund KL, Tee SS, Cross JR, Thompson CB, Keshari KR. In Vivo Imaging of Glutamine Metabolism to the Oncometabolite 2-Hydroxyglutarate in IDH1/2 Mutant Tumors. Cell Metabolism. PMID 29056515 DOI: 10.1016/J.Cmet.2017.10.001 |
0.613 |
|
| 2017 |
Palm W, Araki J, King B, DeMatteo RG, Thompson CB. Critical role for PI3-kinase in regulating the use of proteins as an amino acid source. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973876 DOI: 10.1073/Pnas.1712726114 |
0.346 |
|
| 2017 |
Palm W, Thompson CB. Nutrient acquisition strategies of mammalian cells. Nature. 546: 234-242. PMID 28593971 DOI: 10.1038/Nature22379 |
0.415 |
|
| 2017 |
Zhang J, Pavlova NN, Thompson CB. Cancer cell metabolism: the essential role of the nonessential amino acid, glutamine. The Embo Journal. PMID 28420743 DOI: 10.15252/Embj.201696151 |
0.376 |
|
| 2017 |
Thompson CB, Palm W. Reexamining How Cancer Cells Exploit the Body's Metabolic Resources. Cold Spring Harbor Symposia On Quantitative Biology. PMID 28396524 DOI: 10.1101/Sqb.2016.81.030734 |
0.406 |
|
| 2017 |
Intlekofer AM, Wang B, Liu H, Shah H, Carmona-Fontaine C, Rustenburg AS, Salah S, Gunner MR, Chodera JD, Cross JR, Thompson CB. L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH. Nature Chemical Biology. PMID 28263965 DOI: 10.1038/Nchembio.2307 |
0.613 |
|
| 2017 |
Carmona-Fontaine C, Deforet M, Akkari L, Thompson CB, Joyce JA, Xavier JB. Metabolic origins of spatial organization in the tumor microenvironment. Proceedings of the National Academy of Sciences of the United States of America. PMID 28246332 DOI: 10.1073/Pnas.1700600114 |
0.34 |
|
| 2017 |
Shih AH, Meydan C, Shank K, Garrett-Bakelman FE, Ward PS, Intlekofer A, Nazir A, Stein E, Knapp K, Glass J, Travins J, Straley K, Gliser C, Mason C, Yen K, ... Thompson CB, et al. Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia. Cancer Discovery. PMID 28193779 DOI: 10.1158/2159-8290.Cd-16-1049 |
0.343 |
|
| 2017 |
Chio IIC, Jafarnejad SM, Ponz-Sarvise M, Park Y, Rivera K, Palm W, Ohlund D, Hammell M, Crawford H, Schmidt E, Thompson C, Pappin D, Sonenberg N, Tuveson D. Abstract PR03: NRF2 promotes tumor maintenance by modulating mRNA translation in pancreatic cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Transcontrol16-Pr03 |
0.412 |
|
| 2017 |
Pavlova NN, Zhang J, Thompson CB. Abstract B39: Asparagine drives translational adaptation of cancer cells to glutamine deficit Cancer Research. 77. DOI: 10.1158/1538-7445.Transcontrol16-B39 |
0.382 |
|
| 2016 |
Krishna S, Palm W, Lee Y, Yang W, Bandyopadhyay U, Xu H, Florey O, Thompson CB, Overholtzer M. PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment. Developmental Cell. 38: 536-547. PMID 27623384 DOI: 10.1016/J.Devcel.2016.08.001 |
0.416 |
|
| 2016 |
Chio II, Jafarnejad SM, Ponz-Sarvise M, Park Y, Rivera K, Palm W, Wilson J, Sangar V, Hao Y, Öhlund D, Wright K, Filippini D, Lee EJ, Da Silva B, Schoepfer C, ... ... Thompson CB, et al. NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer. Cell. PMID 27477511 DOI: 10.1016/J.Cell.2016.06.056 |
0.321 |
|
| 2016 |
Olejniczak SH, La Rocca G, Radler MR, Egan SM, Xiang Q, Garippa R, Thompson CB. Coordinated regulation of cap-dependent translation and microRNA function by convergent signaling pathways. Molecular and Cellular Biology. PMID 27354062 DOI: 10.1128/Mcb.01011-15 |
0.353 |
|
| 2016 |
Lu C, Jain SU, Hoelper D, Bechet D, Molden RC, Ran L, Murphy D, Venneti S, Hameed M, Pawel BR, Wunder JS, Dickson BC, Lundgren SM, Jani KS, De Jay N, ... ... Thompson CB, et al. Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape. Science (New York, N.Y.). 352: 844-9. PMID 27174990 DOI: 10.1126/Science.Aac7272 |
0.304 |
|
| 2016 |
Pavlova NN, Thompson CB. The Emerging Hallmarks of Cancer Metabolism. Cell Metabolism. 23: 27-47. PMID 26771115 DOI: 10.1016/J.Cmet.2015.12.006 |
0.356 |
|
| 2016 |
Palm W, Park Y, Wright K, Pavlova NN, Tuveson DA, Thompson CB. Abstract B43: The utilization of extracellular proteins as nutrients is suppressed by mTORC1 Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-B43 |
0.399 |
|
| 2016 |
Pavlova NN, Thompson CB. Abstract A09: The role of asparagine in glutamine-independent proliferation of breast cancer cells Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-A09 |
0.378 |
|
| 2016 |
Thompson CB, Palm W, Ye J, Pavlova NN, King B. Abstract PL02-01: Isogenic tumors can utilize heterogeneous mechanisms of nutrient uptake Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Pl02-01 |
0.39 |
|
| 2016 |
Schvartzman JM, Thompson CB. Abstract 2877: Effects of metabolic stressors on cellular differentiation Cancer Research. 76: 2877-2877. DOI: 10.1158/1538-7445.Am2016-2877 |
0.41 |
|
| 2015 |
Ye J, Palm W, Peng M, King B, Lindsten T, Li MO, Koumenis C, Thompson CB. GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2. Genes & Development. PMID 26543160 DOI: 10.1101/Gad.269324.115 |
0.342 |
|
| 2015 |
Intlekofer AM, Dematteo RG, Venneti S, Finley LW, Lu C, Judkins AR, Rustenburg AS, Grinaway PB, Chodera JD, Cross JR, Thompson CB. Hypoxia Induces Production of L-2-Hydroxyglutarate. Cell Metabolism. PMID 26212717 DOI: 10.1016/J.Cmet.2015.06.023 |
0.604 |
|
| 2015 |
Palm W, Park Y, Wright K, Pavlova NN, Tuveson DA, Thompson CB. The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1. Cell. 162: 259-70. PMID 26144316 DOI: 10.1016/J.Cell.2015.06.017 |
0.39 |
|
| 2015 |
Saleiro D, Mehrotra S, Kroczynska B, Beauchamp EM, Lisowski P, Majchrzak-Kita B, Bhagat TD, Stein BL, McMahon B, Altman JK, Kosciuczuk EM, Baker DP, Jie C, Jafari N, Thompson CB, et al. Central role of ULK1 in type I interferon signaling. Cell Reports. 11: 605-17. PMID 25892232 DOI: 10.1016/J.Celrep.2015.03.056 |
0.318 |
|
| 2015 |
Venneti S, Dunphy MP, Zhang H, Pitter KL, Zanzonico P, Campos C, Carlin SD, La Rocca G, Lyashchenko S, Ploessl K, Rohle D, Omuro AM, Cross JR, Brennan CW, Weber WA, ... ... Thompson CB, et al. Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo. Science Translational Medicine. 7: 274ra17. PMID 25673762 DOI: 10.1126/Scitranslmed.Aaa1009 |
0.577 |
|
| 2015 |
Jiang X, Overholtzer M, Thompson CB. Autophagy in cellular metabolism and cancer. The Journal of Clinical Investigation. 125: 47-54. PMID 25654550 DOI: 10.1172/Jci73942 |
0.351 |
|
| 2015 |
Kamphorst JJ, Nofal M, Commisso C, Hackett SR, Lu W, Grabocka E, Vander Heiden MG, Miller G, Drebin JA, Bar-Sagi D, Thompson CB, Rabinowitz JD. Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein. Cancer Research. 75: 544-53. PMID 25644265 DOI: 10.1158/0008-5472.Can-14-2211 |
0.553 |
|
| 2015 |
La Rocca G, Olejniczak SH, González AJ, Briskin D, Vidigal JA, Spraggon L, DeMatteo RG, Radler MR, Lindsten T, Ventura A, Tuschl T, Leslie CS, Thompson CB. In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA. Proceedings of the National Academy of Sciences of the United States of America. 112: 767-72. PMID 25568082 DOI: 10.1073/Pnas.1424217112 |
0.327 |
|
| 2015 |
Carey BW, Finley LW, Cross JR, Allis CD, Thompson CB. Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells. Nature. 518: 413-6. PMID 25487152 DOI: 10.1038/Nature13981 |
0.661 |
|
| 2015 |
Thompson CB, Intlekofer AM, Dematteo RG, Venneti S, Finley LWS, Lu C, Rustenburg AS, Grinaway PB, Chodera JD, Cross JR, Judkins AR. Abstract SY43-01: Stereochemistry matters: L-2HG as a tumor response to hypoxia Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Sy43-01 |
0.613 |
|
| 2014 |
Zhang J, Fan J, Venneti S, Cross JR, Takagi T, Bhinder B, Djaballah H, Kanai M, Cheng EH, Judkins AR, Pawel B, Baggs J, Cherry S, Rabinowitz JD, Thompson CB. Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion. Molecular Cell. 56: 205-18. PMID 25242145 DOI: 10.1016/J.Molcel.2014.08.018 |
0.63 |
|
| 2014 |
Zhang J, Fan J, Venneti S, Cross JR, Takagi T, Bhinder B, Djaballah H, Kanai M, Cheng EH, Judkins AR, Pawel B, Baggs J, Cherry S, Rabinowitz JD, Thompson CB. Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion. Molecular Cell. 56: 205-18. PMID 25242145 DOI: 10.1016/J.Molcel.2014.08.018 |
0.63 |
|
| 2014 |
Ye J, Fan J, Venneti S, Wan YW, Pawel BR, Zhang J, Finley LW, Lu C, Lindsten T, Cross JR, Qing G, Liu Z, Simon MC, Rabinowitz JD, Thompson CB. Serine catabolism regulates mitochondrial redox control during hypoxia. Cancer Discovery. 4: 1406-17. PMID 25186948 DOI: 10.1158/2159-8290.Cd-14-0250 |
0.635 |
|
| 2014 |
Ye J, Fan J, Venneti S, Wan YW, Pawel BR, Zhang J, Finley LW, Lu C, Lindsten T, Cross JR, Qing G, Liu Z, Simon MC, Rabinowitz JD, Thompson CB. Serine catabolism regulates mitochondrial redox control during hypoxia. Cancer Discovery. 4: 1406-17. PMID 25186948 DOI: 10.1158/2159-8290.Cd-14-0250 |
0.635 |
|
| 2014 |
Thompson CB. Wnt meets Warburg: Another piece in the puzzle? Embo Journal. 33: 1420-1422. PMID 24843042 DOI: 10.15252/Embj.201488785 |
0.336 |
|
| 2014 |
Shi Y, Wang J, Chandarlapaty S, Cross J, Thompson C, Rosen N, Jiang X. PTEN is a protein tyrosine phosphatase for IRS1 Nature Structural and Molecular Biology. 21: 522-527. PMID 24814346 DOI: 10.1038/Nsmb.2828 |
0.6 |
|
| 2014 |
Thompson CB. What cancer is teaching us about cellular metabolism Cancer and Metabolism. 2: 1-1. DOI: 10.1186/2049-3002-2-S1-O32 |
0.427 |
|
| 2014 |
Intlekofer AM, Dematteo RG, Finley LW, Cross JR, Thompson CB. Leukemia-Associated Oncometabolite 2-Hydroxyglutarate Regulates Epigenetic Modifications in Response to Oxygen Availability in Cells without IDH1/2 Mutations Blood. 124: 872-872. DOI: 10.1182/Blood.V124.21.872.872 |
0.623 |
|
| 2014 |
Shih AH, Shank KR, Meydan C, Intlekofer AM, Ward P, Thompson CB, Melnick AM, Travins J, Straley K, Gliser C, Yen K, Levine RL. AG-221, a Small Molecule Mutant IDH2 Inhibitor, Remodels the Epigenetic State of IDH2-Mutant Cells and Induces Alterations in Self-Renewal/Differentiation in IDH2-Mutant AML Model in Vivo Blood. 124: 437-437. DOI: 10.1182/Blood.V124.21.437.437 |
0.343 |
|
| 2014 |
Venneti S, Dunphy M, Zhang H, Pitter K, Campos C, Carlin S, Lyashchenko S, Ploessl C, Rohle D, Omuro A, Cross J, Brennan C, Weber W, Holland E, Mellinghoff I, ... ... Thompson C, et al. TM-15 * GLUTAMINE BASED PET IMAGING FACILITATES ENHANCED METABOLIC DETECTION OF GLIOMAS IN VIVO Neuro-Oncology. 16: v216-v216. DOI: 10.1093/Neuonc/Nou278.14 |
0.579 |
|
| 2013 |
Lu C, Venneti S, Akalin A, Fang F, Ward PS, Dematteo RG, Intlekofer AM, Chen C, Ye J, Hameed M, Nafa K, Agaram NP, Cross JR, Khanin R, Mason CE, ... ... Thompson CB, et al. Induction of sarcomas by mutant IDH2. Genes & Development. 27: 1986-98. PMID 24065766 DOI: 10.1101/Gad.226753.113 |
0.583 |
|
| 2013 |
Lu C, Venneti S, Akalin A, Fang F, Ward PS, Dematteo RG, Intlekofer AM, Chen C, Ye J, Hameed M, Nafa K, Agaram NP, Cross JR, Khanin R, Mason CE, ... ... Thompson CB, et al. Induction of sarcomas by mutant IDH2. Genes & Development. 27: 1986-98. PMID 24065766 DOI: 10.1101/Gad.226753.113 |
0.583 |
|
| 2013 |
Chen C, Liu Y, Lu C, Cross JR, Morris JP, Shroff AS, Ward PS, Bradner JE, Thompson C, Lowe SW. Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition. Genes & Development. 27: 1974-85. PMID 24065765 DOI: 10.1101/Gad.226613.113 |
0.636 |
|
| 2013 |
Kamphorst JJ, Cross JR, Fan J, de Stanchina E, Mathew R, White EP, Thompson CB, Rabinowitz JD. Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids. Proceedings of the National Academy of Sciences of the United States of America. 110: 8882-7. PMID 23671091 DOI: 10.1073/Pnas.1307237110 |
0.58 |
|
| 2013 |
Kamphorst JJ, Cross JR, Fan J, de Stanchina E, Mathew R, White EP, Thompson CB, Rabinowitz JD. Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids. Proceedings of the National Academy of Sciences of the United States of America. 110: 8882-7. PMID 23671091 DOI: 10.1073/Pnas.1307237110 |
0.58 |
|
| 2013 |
Commisso C, Davidson SM, Soydaner-Azeloglu RG, Parker SJ, Kamphorst JJ, Hackett S, Grabocka E, Nofal M, Drebin JA, Thompson CB, Rabinowitz JD, Metallo CM, Vander Heiden MG, Bar-Sagi D. Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells. Nature. 497: 633-7. PMID 23665962 DOI: 10.1038/Nature12138 |
0.513 |
|
| 2013 |
Commisso C, Davidson SM, Soydaner-Azeloglu RG, Parker SJ, Kamphorst JJ, Hackett S, Grabocka E, Nofal M, Drebin JA, Thompson CB, Rabinowitz JD, Metallo CM, Vander Heiden MG, Bar-Sagi D. Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells. Nature. 497: 633-7. PMID 23665962 DOI: 10.1038/Nature12138 |
0.513 |
|
| 2013 |
Venneti S, Thompson CB. Metabolic modulation of epigenetics in gliomas. Brain Pathology (Zurich, Switzerland). 23: 217-21. PMID 23432648 DOI: 10.1111/Bpa.12022 |
0.34 |
|
| 2013 |
Ward PS, Lu C, Cross JR, Abdel-Wahab O, Levine RL, Schwartz GK, Thompson CB. The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization. The Journal of Biological Chemistry. 288: 3804-15. PMID 23264629 DOI: 10.1074/Jbc.M112.435495 |
0.608 |
|
| 2013 |
Olejniczak SH, La Rocca G, Gruber JJ, Thompson CB. Long-lived microRNA-Argonaute complexes in quiescent cells can be activated to regulate mitogenic responses. Proceedings of the National Academy of Sciences of the United States of America. 110: 157-62. PMID 23248281 DOI: 10.1073/Pnas.1219958110 |
0.689 |
|
| 2013 |
Thompson CB. Targeting Metabolic Inputs into Epigenetic Regulations of Acute Leukemia Blood. 122. DOI: 10.1182/Blood.V122.21.Sci-26.Sci-26 |
0.391 |
|
| 2013 |
Venneti S, Garimella M, Sullivan L, Martinez D, Huse J, Heguy A, Santi M, Thompson C, Alexander J. Abstract A01: Evaluation of H3K27me3 and EZH2 in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant GBM Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-A01 |
0.341 |
|
| 2012 |
Qing G, Li B, Vu A, Skuli N, Walton ZE, Liu X, Mayes PA, Wise DR, Thompson CB, Maris JM, Hogarty MD, Simon MC. ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation. Cancer Cell. 22: 631-44. PMID 23153536 DOI: 10.1016/J.Ccr.2012.09.021 |
0.461 |
|
| 2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Thompson CB, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.597 |
|
| 2012 |
Cheong H, Lu C, Lindsten T, Thompson CB. Therapeutic targets in cancer cell metabolism and autophagy. Nature Biotechnology. 30: 671-8. PMID 22781696 DOI: 10.1038/Nbt.2285 |
0.35 |
|
| 2012 |
Lu C, Thompson CB. Metabolic regulation of epigenetics. Cell Metabolism. 16: 9-17. PMID 22768835 DOI: 10.1016/J.Cmet.2012.06.001 |
0.335 |
|
| 2012 |
Ward PS, Thompson CB. Signaling in control of cell growth and metabolism. Cold Spring Harbor Perspectives in Biology. 4: a006783. PMID 22687276 DOI: 10.1101/Cshperspect.A006783 |
0.402 |
|
| 2012 |
Blickwedehl J, Olejniczak S, Cummings R, Sarvaiya N, Mantilla A, Chanan-Khan A, Pandita TK, Schmidt M, Thompson CB, Bangia N. The proteasome activator PA200 regulates tumor cell responsiveness to glutamine and resistance to ionizing radiation. Molecular Cancer Research : McR. 10: 937-44. PMID 22550082 DOI: 10.1158/1541-7786.Mcr-11-0493-T |
0.399 |
|
| 2012 |
Ye J, Mancuso A, Tong X, Ward PS, Fan J, Rabinowitz JD, Thompson CB. Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 109: 6904-9. PMID 22509023 DOI: 10.1073/Pnas.1204176109 |
0.427 |
|
| 2012 |
Whelan RS, Konstantinidis K, Wei AC, Chen Y, Reyna DE, Jha S, Yang Y, Calvert JW, Lindsten T, Thompson CB, Crow MT, Gavathiotis E, Dorn GW, O'Rourke B, Kitsis RN. Bax regulates primary necrosis through mitochondrial dynamics. Proceedings of the National Academy of Sciences of the United States of America. 109: 6566-71. PMID 22493254 DOI: 10.1073/Pnas.1201608109 |
0.413 |
|
| 2012 |
Ward PS, Thompson CB. Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer Cell. 21: 297-308. PMID 22439925 DOI: 10.1016/J.Ccr.2012.02.014 |
0.354 |
|
| 2012 |
Tai X, Van Laethem F, Pobezinsky L, Guinter T, Sharrow SO, Adams A, Granger L, Kruhlak M, Lindsten T, Thompson CB, Feigenbaum L, Singer A. Basis of CTLA-4 function in regulatory and conventional CD4(+) T cells. Blood. 119: 5155-63. PMID 22403258 DOI: 10.1182/Blood-2011-11-388918 |
0.365 |
|
| 2012 |
Wellen KE, Thompson CB. A two-way street: reciprocal regulation of metabolism and signalling. Nature Reviews. Molecular Cell Biology. 13: 270-6. PMID 22395772 DOI: 10.1038/Nrm3305 |
0.333 |
|
| 2012 |
Lu C, Ward PS, Kapoor GS, Rohle D, Turcan S, Abdel-Wahab O, Edwards CR, Khanin R, Figueroa ME, Melnick A, Wellen KE, O'Rourke DM, Berger SL, Chan TA, Levine RL, ... ... Thompson CB, et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature. 483: 474-8. PMID 22343901 DOI: 10.1038/Nature10860 |
0.354 |
|
| 2012 |
Turcan S, Rohle D, Goenka A, Walsh LA, Fang F, Yilmaz E, Campos C, Fabius AW, Lu C, Ward PS, Thompson CB, Kaufman A, Guryanova O, Levine R, Heguy A, et al. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature. 483: 479-83. PMID 22343889 DOI: 10.1038/Nature10866 |
0.308 |
|
| 2012 |
Gruber JJ, Olejniczak SH, Yong J, La Rocca G, Dreyfuss G, Thompson CB. Ars2 promotes proper replication-dependent histone mRNA 3' end formation. Molecular Cell. 45: 87-98. PMID 22244333 DOI: 10.1016/J.Molcel.2011.12.020 |
0.65 |
|
| 2012 |
Qu W, Oya S, Lieberman BP, Ploessl K, Wang L, Wise DR, Divgi CR, Chodosh LA, Chodosh LP, Thompson CB, Kung HF. Preparation and characterization of L-[5-11C]-glutamine for metabolic imaging of tumors. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 98-105. PMID 22173839 DOI: 10.2967/Jnumed.111.093831 |
0.359 |
|
| 2012 |
Cheong H, Lindsten T, Thompson CB. Autophagy and ammonia. Autophagy. 8: 122-3. PMID 22170154 DOI: 10.4161/Auto.8.1.18078 |
0.397 |
|
| 2012 |
Ward PS, Cross JR, Lu C, Weigert O, Abel-Wahab O, Levine RL, Weinstock DM, Sharp KA, Thompson CB. Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production. Oncogene. 31: 2491-8. PMID 21996744 DOI: 10.1038/Onc.2011.416 |
0.59 |
|
| 2012 |
Kamphorst JJ, Cross JR, Fan J, Lu W, White E, Thompson CB, Rabinowitz JD. Ras-driven cancer cells can scavenge exogenous lipids to support their proliferation Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S3-P25 |
0.626 |
|
| 2012 |
Thompson CB. Beyond insulin: rethinking cellular metabolism Bmc Proceedings. 6: 1-1. DOI: 10.1186/1753-6561-6-S3-O25 |
0.306 |
|
| 2012 |
Rajeshkumar NV, Dutta P, Kamphorst J, Le A, Yabuuchi S, Wilde RFd, Campbell NR, Oliveira ED, Jesus-Acosta AD, Rabinowitz J, Laheru D, Jain SK, Hidalgo M, Thompson CB, Hoff DDV, et al. Abstract LB-61: Targeting cancer cell metabolism in pancreatic cancer: p53, a key regulator of glycolysis and a major factor deciding the outcome of targeting the Warburg effect Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-61 |
0.361 |
|
| 2011 |
Thompson CB. Rethinking the regulation of cellular metabolism. Cold Spring Harbor Symposia On Quantitative Biology. 76: 23-9. PMID 22429931 DOI: 10.1101/Sqb.2012.76.010496 |
0.387 |
|
| 2011 |
Wise DR, Ward PS, Shay JE, Cross JR, Gruber JJ, Sachdeva UM, Platt JM, DeMatteo RG, Simon MC, Thompson CB. Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability. Proceedings of the National Academy of Sciences of the United States of America. 108: 19611-6. PMID 22106302 DOI: 10.1073/Pnas.1117773108 |
0.797 |
|
| 2011 |
Joo JH, Dorsey FC, Joshi A, Hennessy-Walters KM, Rose KL, McCastlain K, Zhang J, Iyengar R, Jung CH, Suen DF, Steeves MA, Yang CY, Prater SM, Kim DH, Thompson CB, et al. Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy. Molecular Cell. 43: 572-85. PMID 21855797 DOI: 10.1016/J.Molcel.2011.06.018 |
0.336 |
|
| 2011 |
Cheong H, Lindsten T, Wu J, Lu C, Thompson CB. Ammonia-induced autophagy is independent of ULK1/ULK2 kinases. Proceedings of the National Academy of Sciences of the United States of America. 108: 11121-6. PMID 21690395 DOI: 10.1073/Pnas.1107969108 |
0.394 |
|
| 2011 |
Qu W, Zha Z, Lieberman BP, Mancuso A, Stetz M, Rizzi R, Ploessl K, Wise D, Thompson C, Kung HF. Facile Synthesis [5- 13C-4- 2H 2]-L-Glutamine for Hyperpolarized MRS Imaging of Cancer Cell Metabolism Academic Radiology. 18: 932-939. PMID 21658976 DOI: 10.1016/J.Acra.2011.05.002 |
0.327 |
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| 2011 |
Zaugg K, Yao Y, Reilly PT, Kannan K, Kiarash R, Mason J, Huang P, Sawyer SK, Fuerth B, Faubert B, Kalliomäki T, Elia A, Luo X, Nadeem V, Bungard D, ... ... Thompson CB, et al. Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress. Genes & Development. 25: 1041-51. PMID 21576264 DOI: 10.1101/Gad.1987211 |
0.4 |
|
| 2011 |
Melnick AM, Levine RL, Figueroa ME, Thompson CB, Abdel-Wahab O. Epigenetic Effects of IDH1/IDH2 Mutations Blood. 118. DOI: 10.1182/Blood.V118.21.Sci-33.Sci-33 |
0.344 |
|
| 2011 |
Welliver MX, Hart LS, Ye J, Lu C, Mick R, Kong M, Ditsworth D, Mesina A, Zhao F, Guerriero JL, Zong W, Koumenis C, Thompson CB. Abstract 2513: Molecular dissection of cell death mechanisms following ionizing radiationin vitroandin vivo Cancer Research. 71: 2513-2513. DOI: 10.1158/1538-7445.Am2011-2513 |
0.766 |
|
| 2010 |
Figueroa ME, Abdel-Wahab O, Lu C, Ward PS, Patel J, Shih A, Li Y, Bhagwat N, Vasanthakumar A, Fernandez HF, Tallman MS, Sun Z, Wolniak K, Peeters JK, Liu W, ... ... Thompson CB, et al. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell. 18: 553-67. PMID 21130701 DOI: 10.1016/J.Ccr.2010.11.015 |
0.333 |
|
| 2010 |
Wellen KE, Lu C, Mancuso A, Lemons JM, Ryczko M, Dennis JW, Rabinowitz JD, Coller HA, Thompson CB. The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism. Genes & Development. 24: 2784-99. PMID 21106670 DOI: 10.1101/Gad.1985910 |
0.361 |
|
| 2010 |
Wellen KE, Thompson CB. Cellular metabolic stress: considering how cells respond to nutrient excess. Molecular Cell. 40: 323-32. PMID 20965425 DOI: 10.1016/J.Molcel.2010.10.004 |
0.386 |
|
| 2010 |
Cárdenas C, Miller RA, Smith I, Bui T, Molgó J, Müller M, Vais H, Cheung KH, Yang J, Parker I, Thompson CB, Birnbaum MJ, Hallows KR, Foskett JK. Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria. Cell. 142: 270-83. PMID 20655468 DOI: 10.1016/J.Cell.2010.06.007 |
0.343 |
|
| 2010 |
Bungard D, Fuerth BJ, Zeng PY, Faubert B, Maas NL, Viollet B, Carling D, Thompson CB, Jones RG, Berger SL. Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. Science (New York, N.Y.). 329: 1201-5. PMID 20647423 DOI: 10.1126/Science.1191241 |
0.33 |
|
| 2010 |
Moser TS, Jones RG, Thompson CB, Coyne CB, Cherry S. A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynamics. Plos Pathogens. 6: e1000954. PMID 20585561 DOI: 10.1371/Journal.Ppat.1000954 |
0.302 |
|
| 2010 |
Wise DR, Thompson CB. Glutamine addiction: a new therapeutic target in cancer. Trends in Biochemical Sciences. 35: 427-33. PMID 20570523 DOI: 10.1016/J.Tibs.2010.05.003 |
0.375 |
|
| 2010 |
Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, Fantin VR, Jang HG, Jin S, Keenan MC, Marks KM, Prins RM, Ward PS, Yen KE, Liau LM, ... ... Thompson CB, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 465: 966. PMID 20559394 DOI: 10.1038/nature09132 |
0.544 |
|
| 2010 |
Kaelin WG, Thompson CB. Q&A: Cancer: clues from cell metabolism. Nature. 465: 562-4. PMID 20520704 DOI: 10.1038/465562A |
0.341 |
|
| 2010 |
Krawczyk CM, Holowka T, Sun J, Blagih J, Amiel E, DeBerardinis RJ, Cross JR, Jung E, Thompson CB, Jones RG, Pearce EJ. Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation. Blood. 115: 4742-9. PMID 20351312 DOI: 10.1182/Blood-2009-10-249540 |
0.616 |
|
| 2010 |
Zhao F, Mancuso A, Bui TV, Tong X, Gruber JJ, Swider CR, Sanchez PV, Lum JJ, Sayed N, Melo JV, Perl AE, Carroll M, Tuttle SW, Thompson CB. Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1alpha-induced metabolic reprograming. Oncogene. 29: 2962-72. PMID 20228846 DOI: 10.1038/Onc.2010.67 |
0.71 |
|
| 2010 |
Ward PS, Patel J, Wise DR, Abdel-Wahab O, Bennett BD, Coller HA, Cross JR, Fantin VR, Hedvat CV, Perl AE, Rabinowitz JD, Carroll M, Su SM, Sharp KA, Levine RL, ... Thompson CB, et al. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell. 17: 225-34. PMID 20171147 DOI: 10.1016/J.Ccr.2010.01.020 |
0.584 |
|
| 2010 |
Fantin VR, Dang L, White DW, Gross S, Bittinger MA, Driggers EM, Jang HG, Jin S, Keenan MC, Marks KM, Yen KE, Ward PS, Prins RM, Liau LM, Bennett BD, ... ... Thompson CB, et al. Abstract 33: Cancer-associated IDH1 mutations produce 2-hydroxyglutarate Cancer Research. 70: 33-33. DOI: 10.1158/1538-7445.Am10-33 |
0.468 |
|
| 2010 |
Welliver M, Kong M, Ditsworth D, Guerriero J, Zong W, Zhao F, Lu C, Koumenis C, Thompson C. Investigation of Radiation Induced Cell Death Mechanisms International Journal of Radiation Oncology*Biology*Physics. 78: S626-S627. DOI: 10.1016/J.Ijrobp.2010.07.1458 |
0.75 |
|
| 2009 |
Tong X, Zhao F, Mancuso A, Gruber JJ, Thompson CB. The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 106: 21660-5. PMID 19995986 DOI: 10.1073/Pnas.0911316106 |
0.721 |
|
| 2009 |
Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, Fantin VR, Jang HG, Jin S, Keenan MC, Marks KM, Prins RM, Ward PS, Yen KE, Liau LM, ... ... Thompson CB, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 462: 739-44. PMID 19935646 DOI: 10.1038/Nature08617 |
0.693 |
|
| 2009 |
Sabin LR, Zhou R, Gruber JJ, Lukinova N, Bambina S, Berman A, Lau CK, Thompson CB, Cherry S. Ars2 regulates both miRNA- and siRNA- dependent silencing and suppresses RNA virus infection in Drosophila. Cell. 138: 340-51. PMID 19632183 DOI: 10.1016/J.Cell.2009.04.045 |
0.65 |
|
| 2009 |
Gruber JJ, Zatechka DS, Sabin LR, Yong J, Lum JJ, Kong M, Zong WX, Zhang Z, Lau CK, Rawlings J, Cherry S, Ihle JN, Dreyfuss G, Thompson CB. Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell. 138: 328-39. PMID 19632182 DOI: 10.1016/J.Cell.2009.04.046 |
0.755 |
|
| 2009 |
Nogueira CV, Lindsten T, Jamieson AM, Case CL, Shin S, Thompson CB, Roy CR. Rapid pathogen-induced apoptosis: a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila. Plos Pathogens. 5: e1000478. PMID 19521510 DOI: 10.1371/Journal.Ppat.1000478 |
0.345 |
|
| 2009 |
Wellen KE, Hatzivassiliou G, Sachdeva UM, Bui TV, Cross JR, Thompson CB. ATP-citrate lyase links cellular metabolism to histone acetylation. Science (New York, N.Y.). 324: 1076-80. PMID 19461003 DOI: 10.1126/Science.1164097 |
0.611 |
|
| 2009 |
Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science (New York, N.Y.). 324: 1029-33. PMID 19460998 DOI: 10.1126/Science.1160809 |
0.677 |
|
| 2009 |
Madesh M, Zong WX, Hawkins BJ, Ramasamy S, Venkatachalam T, Mukhopadhyay P, Doonan PJ, Irrinki KM, Rajesh M, Pacher P, Thompson CB. Execution of superoxide-induced cell death by the proapoptotic Bcl-2-related proteins Bid and Bak. Molecular and Cellular Biology. 29: 3099-112. PMID 19332555 DOI: 10.1128/Mcb.01845-08 |
0.626 |
|
| 2009 |
Jones RG, Thompson CB. Tumor suppressors and cell metabolism: a recipe for cancer growth. Genes & Development. 23: 537-48. PMID 19270154 DOI: 10.1101/Gad.1756509 |
0.374 |
|
| 2009 |
Tong X, Zhao F, Thompson CB. The molecular determinants of de novo nucleotide biosynthesis in cancer cells. Current Opinion in Genetics & Development. 19: 32-7. PMID 19201187 DOI: 10.1016/J.Gde.2009.01.002 |
0.389 |
|
| 2008 |
Wise DR, DeBerardinis RJ, Mancuso A, Sayed N, Zhang XY, Pfeiffer HK, Nissim I, Daikhin E, Yudkoff M, McMahon SB, Thompson CB. Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction. Proceedings of the National Academy of Sciences of the United States of America. 105: 18782-7. PMID 19033189 DOI: 10.1073/Pnas.0810199105 |
0.423 |
|
| 2008 |
Bobrovnikova-Marjon E, Hatzivassiliou G, Grigoriadou C, Romero M, Cavener DR, Thompson CB, Diehl JA. PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation. Proceedings of the National Academy of Sciences of the United States of America. 105: 16314-9. PMID 18852460 DOI: 10.1073/Pnas.0808517105 |
0.358 |
|
| 2008 |
Kundu M, Lindsten T, Yang CY, Wu J, Zhao F, Zhang J, Selak MA, Ney PA, Thompson CB. Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation. Blood. 112: 1493-502. PMID 18539900 DOI: 10.1182/Blood-2008-02-137398 |
0.4 |
|
| 2008 |
Sachdeva UM, Thompson CB. Diurnal rhythms of autophagy: implications for cell biology and human disease. Autophagy. 4: 581-9. PMID 18437053 DOI: 10.4161/Auto.6141 |
0.382 |
|
| 2008 |
Deberardinis RJ, Sayed N, Ditsworth D, Thompson CB. Brick by brick: metabolism and tumor cell growth. Current Opinion in Genetics & Development. 18: 54-61. PMID 18387799 DOI: 10.1016/J.Gde.2008.02.003 |
0.386 |
|
| 2008 |
DeBerardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metabolism. 7: 11-20. PMID 18177721 DOI: 10.1016/J.Cmet.2007.10.002 |
0.453 |
|
| 2008 |
Kundu M, Thompson CB. Autophagy: basic principles and relevance to disease. Annual Review of Pathology. 3: 427-55. PMID 18039129 DOI: 10.1146/Annurev.Pathmechdis.2.010506.091842 |
0.34 |
|
| 2008 |
Woodland RT, Fox CJ, Schmidt MR, Hammerman PS, Opferman JT, Korsmeyer SJ, Hilbert DM, Thompson CB. Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival. Blood. 111: 750-60. PMID 17942753 DOI: 10.1182/Blood-2007-03-077222 |
0.401 |
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| 2008 |
Pecqueur C, Bui T, Gelly C, Hauchard J, Barbot C, Bouillaud F, Ricquier D, Miroux B, Thompson CB. Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 9-18. PMID 17855623 DOI: 10.1096/Fj.07-8945Com |
0.394 |
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| 2008 |
Kundu M, Yang C, McCastlain K, Wu J, Zhang J, Lindsten T, Ney P, Thompson CB. Hsp90 regulates Ulk1-mediated autophagic clearance of mitochondria Blood. 112: 3458-3458. DOI: 10.1182/Blood.V112.11.3458.3458 |
0.363 |
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| 2008 |
Zhang AY, Robinson BW, Wang L, Kao K, Cory L, Barrett JS, Atlas S, Chen I, Harvey RC, Willman CL, Devidas M, Carroll AJ, Hunger SP, Moore JS, Thompson CB, et al. Pan-Anti-Apoptotic BCL-2 Family Inhibitor, Obatoclax, Activates Autophagic Cell Death Pathway and Has Potent Cytotoxicity in Infant and Pediatric MLL-Rearranged Leukemias Blood. 112: 2647-2647. DOI: 10.1182/Blood.V112.11.2647.2647 |
0.388 |
|
| 2007 |
Amaravadi RK, Thompson CB. The roles of therapy-induced autophagy and necrosis in cancer treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 7271-9. PMID 18094407 DOI: 10.1158/1078-0432.Ccr-07-1595 |
0.419 |
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| 2007 |
DeBerardinis RJ, Mancuso A, Daikhin E, Nissim I, Yudkoff M, Wehrli S, Thompson CB. Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proceedings of the National Academy of Sciences of the United States of America. 104: 19345-50. PMID 18032601 DOI: 10.1073/Pnas.0709747104 |
0.397 |
|
| 2007 |
Jones RG, Thompson CB. Revving the engine: signal transduction fuels T cell activation. Immunity. 27: 173-8. PMID 17723208 DOI: 10.1016/J.Immuni.2007.07.008 |
0.355 |
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| 2007 |
Kong M, Bui TV, Ditsworth D, Gruber JJ, Goncharov D, Krymskaya VP, Lindsten T, Thompson CB. The PP2A-associated protein alpha4 plays a critical role in the regulation of cell spreading and migration. The Journal of Biological Chemistry. 282: 29712-20. PMID 17693407 DOI: 10.1074/Jbc.M703159200 |
0.68 |
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| 2007 |
Gordan JD, Thompson CB, Simon MC. HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation. Cancer Cell. 12: 108-13. PMID 17692803 DOI: 10.1016/J.Ccr.2007.07.006 |
0.4 |
|
| 2007 |
Jones RG, Bui T, White C, Madesh M, Krawczyk CM, Lindsten T, Hawkins BJ, Kubek S, Frauwirth KA, Wang YL, Conway SJ, Roderick HL, Bootman MD, Shen H, Foskett JK, ... Thompson CB, et al. The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis. Immunity. 27: 268-80. PMID 17692540 DOI: 10.1016/J.Immuni.2007.05.023 |
0.363 |
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| 2007 |
Buzzai M, Jones RG, Amaravadi RK, Lum JJ, DeBerardinis RJ, Zhao F, Viollet B, Thompson CB. Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth. Cancer Research. 67: 6745-52. PMID 17638885 DOI: 10.1158/0008-5472.Can-06-4447 |
0.351 |
|
| 2007 |
Li C, Wang X, Vais H, Thompson CB, Foskett JK, White C. Apoptosis regulation by Bcl-x(L) modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating. Proceedings of the National Academy of Sciences of the United States of America. 104: 12565-70. PMID 17636122 DOI: 10.1073/Pnas.0702489104 |
0.305 |
|
| 2007 |
Lum JJ, Bui T, Gruber M, Gordan JD, DeBerardinis RJ, Covello KL, Simon MC, Thompson CB. The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis. Genes & Development. 21: 1037-49. PMID 17437992 DOI: 10.1101/Gad.1529107 |
0.355 |
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| 2007 |
Ditsworth D, Zong WX, Thompson CB. Activation of poly(ADP)-ribose polymerase (PARP-1) induces release of the pro-inflammatory mediator HMGB1 from the nucleus. The Journal of Biological Chemistry. 282: 17845-54. PMID 17430886 DOI: 10.1074/Jbc.M701465200 |
0.64 |
|
| 2007 |
Amaravadi RK, Yu D, Lum JJ, Bui T, Christophorou MA, Evan GI, Thomas-Tikhonenko A, Thompson CB. Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. The Journal of Clinical Investigation. 117: 326-36. PMID 17235397 DOI: 10.1172/Jci28833 |
0.417 |
|
| 2007 |
Brunelle JK, Shroff EH, Perlman H, Strasser A, Moraes CT, Flavell RA, Danial NN, Keith B, Thompson CB, Chandel NS. Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death. Molecular and Cellular Biology. 27: 1222-35. PMID 17145774 DOI: 10.1128/Mcb.01535-06 |
0.447 |
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| 2007 |
Thompson CB. The metabolism of cell growth: aerobic glycolysis The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A45 |
0.342 |
|
| 2006 |
Boxer RB, Stairs DB, Dugan KD, Notarfrancesco KL, Portocarrero CP, Keister BA, Belka GK, Cho H, Rathmell JC, Thompson CB, Birnbaum MJ, Chodosh LA. Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation. Cell Metabolism. 4: 475-90. PMID 17141631 DOI: 10.1016/J.Cmet.2006.10.011 |
0.35 |
|
| 2006 |
Deberardinis RJ, Lum JJ, Thompson CB. Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth. The Journal of Biological Chemistry. 281: 37372-80. PMID 17030509 DOI: 10.1074/Jbc.M608372200 |
0.354 |
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| 2006 |
Woodland RT, Schmidt MR, Thompson CB. BLyS and B cell homeostasis. Seminars in Immunology. 18: 318-26. PMID 16931037 DOI: 10.1016/J.Smim.2006.06.001 |
0.35 |
|
| 2006 |
Bui T, Thompson CB. Cancer's sweet tooth Cancer Cell. 9: 419-420. PMID 16766260 DOI: 10.1016/J.Ccr.2006.05.012 |
0.359 |
|
| 2006 |
Liu L, Cash TP, Jones RG, Keith B, Thompson CB, Simon MC. Hypoxia-induced energy stress regulates mRNA translation and cell growth Molecular Cell. 21: 521-531. PMID 16483933 DOI: 10.1016/J.Molcel.2006.01.010 |
0.393 |
|
| 2006 |
Muthumani K, Choo AY, Zong WX, Madesh M, Hwang DS, Premkumar A, Thieu KP, Emmanuel J, Kumar S, Thompson CB, Weiner DB. The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1. Nature Cell Biology. 8: 170-9. PMID 16429131 DOI: 10.1038/ncb1352 |
0.617 |
|
| 2006 |
Zong WX, Thompson CB. Necrotic death as a cell fate. Genes & Development. 20: 1-15. PMID 16391229 DOI: 10.1101/Gad.1376506 |
0.652 |
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| 2005 |
Thompson CB, Bauer DE, Lum JJ, Hatzivassiliou G, Zong WX, Ditsworth D, Zhao F, Buzzai M, Lindsten T. How do cancer cells acquire the fuel needed to support cell growth? Cold Spring Harbor Symposia On Quantitative Biology. 70: 357-362. PMID 16869772 DOI: 10.1101/Sqb.2005.70.011 |
0.443 |
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| 2005 |
Plas DR, Thompson CB. Akt-dependent transformation: there is more to growth than just surviving. Oncogene. 24: 7435-42. PMID 16288290 DOI: 10.1038/Sj.Onc.1209097 |
0.407 |
|
| 2005 |
Kundu M, Thompson CB. Macroautophagy versus mitochondrial autophagy: A question of fate? Cell Death and Differentiation. 12: 1484-1489. PMID 16247496 DOI: 10.1038/Sj.Cdd.4401780 |
0.431 |
|
| 2005 |
Fox CJ, Hammerman PS, Thompson CB. Fuel feeds function: Energy metabolism and the T-cell response Nature Reviews Immunology. 5: 844-852. PMID 16239903 DOI: 10.1038/Nri1710 |
0.368 |
|
| 2005 |
Parry RV, Chemnitz JM, Frauwirth KA, Lanfranco AR, Braunstein I, Kobayashi SV, Linsley PS, Thompson CB, Riley JL. CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms. Molecular and Cellular Biology. 25: 9543-53. PMID 16227604 DOI: 10.1128/Mcb.25.21.9543-9553.2005 |
0.312 |
|
| 2005 |
Hatzivassiliou G, Zhao F, Bauer DE, Andreadis C, Shaw AN, Dhanak D, Hingorani SR, Tuveson DA, Thompson CB. ATP citrate lyase inhibition can suppress tumor cell growth. Cancer Cell. 8: 311-21. PMID 16226706 DOI: 10.1016/J.Ccr.2005.09.008 |
0.357 |
|
| 2005 |
White C, Li C, Yang J, Petrenko NB, Madesh M, Thompson CB, Foskett JK. The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP3R. Nature Cell Biology. 7: 1021-8. PMID 16179951 DOI: 10.1038/Ncb1302 |
0.328 |
|
| 2005 |
Bauer DE, Hatzivassiliou G, Zhao F, Andreadis C, Thompson CB. ATP citrate lyase is an important component of cell growth and transformation. Oncogene. 24: 6314-22. PMID 16007201 DOI: 10.1038/Sj.Onc.1208773 |
0.404 |
|
| 2005 |
Lum JJ, DeBerardinis RJ, Thompson CB. Autophagy in metazoans: cell survival in the land of plenty. Nature Reviews. Molecular Cell Biology. 6: 439-48. PMID 15928708 DOI: 10.1038/Nrm1660 |
0.387 |
|
| 2005 |
Oltersdorf T, Elmore SW, Shoemaker AR, Armstrong RC, Augeri DJ, Belli BA, Bruncko M, Deckwerth TL, Dinges J, Hajduk PJ, Joseph MK, Kitada S, Korsmeyer SJ, Kunzer AR, Letai A, ... ... Thompson CB, et al. An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature. 435: 677-81. PMID 15902208 DOI: 10.1038/Nature03579 |
0.39 |
|
| 2005 |
Jones RG, Plas DR, Kubek S, Buzzai M, Mu J, Xu Y, Birnbaum MJ, Thompson CB. AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Molecular Cell. 18: 283-93. PMID 15866171 DOI: 10.1016/J.Molcel.2005.03.027 |
0.419 |
|
| 2005 |
Buzzai M, Bauer DE, Jones RG, DeBerardinis RJ, Hatzivassiliou G, Elstrom RL, Thompson CB. The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid β-oxidation Oncogene. 24: 4165-4173. PMID 15806154 DOI: 10.1038/Sj.Onc.1208622 |
0.407 |
|
| 2005 |
Cinalli RM, Herman CE, Lew BO, Wieman HL, Thompson CB, Rathmell JC. T cell homeostasis requires G protein-coupled receptor-mediated access to trophic signals that promote growth and inhibit chemotaxis. European Journal of Immunology. 35: 786-95. PMID 15719365 DOI: 10.1002/Eji.200425729 |
0.364 |
|
| 2005 |
Hammerman PS, Fox CJ, Birnbaum MJ, Thompson CB. Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival. Blood. 105: 4477-83. PMID 15705789 DOI: 10.1182/Blood-2004-09-3706 |
0.424 |
|
| 2005 |
Lum JJ, Bauer DE, Kong M, Harris MH, Li C, Lindsten T, Thompson CB. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell. 120: 237-48. PMID 15680329 DOI: 10.1016/J.Cell.2004.11.046 |
0.421 |
|
| 2005 |
Selak MA, Armour SM, MacKenzie ED, Boulahbel H, Watson DG, Mansfield KD, Pan Y, Simon MC, Thompson CB, Gottlieb E. Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. Cancer Cell. 7: 77-85. PMID 15652751 DOI: 10.1016/J.Ccr.2004.11.022 |
0.341 |
|
| 2005 |
Fox CJ, Hammerman PS, Thompson CB. The Pim kinases control rapamycin-resistant T cell survival and activation Journal of Experimental Medicine. 201: 259-266. PMID 15642745 DOI: 10.1084/Jem.20042020 |
0.388 |
|
| 2005 |
Lindsten T, Zong WX, Thompson CB. Defining the role of the Bcl-2 family of proteins in the nervous system. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 11: 10-5. PMID 15632274 DOI: 10.1177/1073858404269267 |
0.653 |
|
| 2005 |
Amaravadi RK, Yu D, Thomas-Tikhonenko A, Thompson CB. Chloroquine Inhibits Autophagy, Enhances p53-Dependent Apoptosis, and Delays Tumor Recurrence in a Mouse Model of B Cell Lymphoma. Blood. 106: 2421-2421. DOI: 10.1182/Blood.V106.11.2421.2421 |
0.363 |
|
| 2005 |
Zweidler-McKay PA, Lum JJ, Thompson CB, Pear WS. A Critical Role for the Bcl-2 Pathway in Notch-Mediated B Cell Apoptosis, Where Growth Arrest Is Independent of the E2A, IL-3 and p21Waf1/p27Kip1 Pathways. Blood. 106: 237-237. DOI: 10.1182/Blood.V106.11.237.237 |
0.422 |
|
| 2005 |
Hatzivassiliou G, Andreadis C, Thompson CB. Akt-directed metabolic alterations in cancer Drug Discovery Today: Disease Mechanisms. 2: 255-262. DOI: 10.1016/J.Ddmec.2005.05.007 |
0.387 |
|
| 2005 |
Thompson C. Stanley J. Korsmeyer Cell. 121: 319-320. DOI: 10.1016/J.Cell.2005.04.023 |
0.403 |
|
| 2005 |
Thompson C. Stanley J. Korsmeyer Cancer Cell. 7: 401-402. DOI: 10.1016/J.Ccr.2005.05.001 |
0.403 |
|
| 2004 |
Majewski N, Nogueira V, Bhaskar P, Coy PE, Skeen JE, Gottlob K, Chandel NS, Thompson CB, Robey RB, Hay N. Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. Molecular Cell. 16: 819-30. PMID 15574336 DOI: 10.1016/J.Molcel.2004.11.014 |
0.368 |
|
| 2004 |
Shimizu S, Kanaseki T, Mizushima N, Mizuta T, Arakawa-Kobayashi S, Thompson CB, Tsujimoto Y. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nature Cell Biology. 6: 1221-1228. PMID 15558033 DOI: 10.1038/Ncb1192 |
0.392 |
|
| 2004 |
Hammerman PS, Fox CJ, Cinalli RM, Xu A, Wagner JD, Lindsten T, Thompson CB. Lymphocyte transformation by Pim-2 is dependent on nuclear factor-kappaB activation. Cancer Research. 64: 8341-8. PMID 15548703 DOI: 10.1158/0008-5472.Can-04-2284 |
0.362 |
|
| 2004 |
Edinger AL, Thompson CB. Death by design: apoptosis, necrosis and autophagy. Current Opinion in Cell Biology. 16: 663-9. PMID 15530778 DOI: 10.1016/J.Ceb.2004.09.011 |
0.38 |
|
| 2004 |
Hammerman PS, Fox CJ, Thompson CB. Beginnings of a signal-transduction pathway for bioenergetic control of cell survival Trends in Biochemical Sciences. 29: 586-592. PMID 15501677 DOI: 10.1016/J.Tibs.2004.09.008 |
0.412 |
|
| 2004 |
Kong M, Fox CJ, Mu J, Solt L, Xu A, Cinalli RM, Birnbaum MJ, Lindsten T, Thompson CB. The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis. Science (New York, N.Y.). 306: 695-8. PMID 15499020 DOI: 10.1126/Science.1100537 |
0.372 |
|
| 2004 |
Thompson JE, Thompson CB. Putting the rap on Akt. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 4217-26. PMID 15483033 DOI: 10.1200/Jco.2004.01.103 |
0.341 |
|
| 2004 |
Hahn P, Lindsten T, Lyubarsky A, Ying GS, Pugh EN, Thompson CB, Dunaief JL. Deficiency of Bax and Bak protects photoreceptors from light damage in vivo. Cell Death and Differentiation. 11: 1192-7. PMID 15272317 DOI: 10.1038/Sj.Cdd.4401486 |
0.305 |
|
| 2004 |
Bauer DE, Harris MH, Plas DR, Lum JJ, Hammerman PS, Rathmell JC, Riley JL, Thompson CB. Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1303-5. PMID 15180958 DOI: 10.1096/Fj.03-1001Fje |
0.37 |
|
| 2004 |
Elstrom RL, Bauer DE, Buzzai M, Karnauskas R, Harris MH, Plas DR, Zhuang H, Cinalli RM, Alavi A, Rudin CM, Thompson CB. Akt stimulates aerobic glycolysis in cancer cells. Cancer Research. 64: 3892-9. PMID 15172999 DOI: 10.1158/0008-5472.Can-03-2904 |
0.797 |
|
| 2004 |
Arsham AM, Plas DR, Thompson CB, Simon MC. Akt and hypoxia-inducible factor-1 independently enhance tumor growth and angiogenesis. Cancer Research. 64: 3500-7. PMID 15150104 DOI: 10.1158/0008-5472.Can-03-2239 |
0.353 |
|
| 2004 |
Zong WX, Ditsworth D, Bauer DE, Wang ZQ, Thompson CB. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes & Development. 18: 1272-82. PMID 15145826 DOI: 10.1101/Gad.1199904 |
0.674 |
|
| 2004 |
Edinger AL, Thompson CB. An activated mTOR mutant supports growth factor-independent, nutrient-dependent cell survival. Oncogene. 23: 5654-63. PMID 15133498 DOI: 10.1038/Sj.Onc.1207738 |
0.39 |
|
| 2004 |
Frauwirth KA, Thompson CB. Regulation of T lymphocyte metabolism. Journal of Immunology (Baltimore, Md. : 1950). 172: 4661-5. PMID 15067038 DOI: 10.4049/Jimmunol.172.8.4661 |
0.38 |
|
| 2004 |
Conejo-Garcia JR, Benencia F, Courreges MC, Gimotty PA, Khang E, Buckanovich RJ, Frauwirth KA, Zhang L, Katsaros D, Thompson CB, Levine B, Coukos G. Ovarian carcinoma expresses the NKG2D ligand Letal and promotes the survival and expansion of CD28- antitumor T cells. Cancer Research. 64: 2175-82. PMID 15026360 DOI: 10.1158/0008-5472.Can-03-2194 |
0.347 |
|
| 2004 |
Melino G, Bernassola F, Ranalli M, Yee K, Zong WX, Corazzari M, Knight RA, Green DR, Thompson C, Vousden KH. p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation. The Journal of Biological Chemistry. 279: 8076-83. PMID 14634023 DOI: 10.1074/Jbc.M307469200 |
0.644 |
|
| 2004 |
Brunelle JK, Santore MT, Budinger GR, Tang Y, Barrett TA, Zong WX, Kandel E, Keith B, Simon MC, Thompson CB, Hay N, Chandel NS. c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1. The Journal of Biological Chemistry. 279: 4305-12. PMID 14627695 DOI: 10.1074/Jbc.M312241200 |
0.653 |
|
| 2004 |
Chemnitz JM, Riley JL, Frauwirth KA, Braunstein I, Kobayashi SV, Linsley PS, Thompson CB, Parry RV. CTLA-4 and PD-1 Receptors Inhibit T-Cell Activation by Distinct Mechanisms. Blood. 104: 2657-2657. DOI: 10.1182/Blood.V104.11.2657.2657 |
0.319 |
|
| 2004 |
Bauer DE, Thompson CB. 16 Lymphocyte Growth Cold Spring Harbor Monograph Archive. 42: 509-527. DOI: 10.1101/087969672.42.509 |
0.37 |
|
| 2003 |
Edinger AL, Thompson CB. Defective autophagy leads to cancer. Cancer Cell. 4: 422-4. PMID 14706333 DOI: 10.1016/S1535-6108(03)00306-4 |
0.332 |
|
| 2003 |
Lindsten T, Golden JA, Zong WX, Minarcik J, Harris MH, Thompson CB. The proapoptotic activities of Bax and Bak limit the size of the neural stem cell pool. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 11112-9. PMID 14657169 DOI: 10.1523/Jneurosci.23-35-11112.2003 |
0.602 |
|
| 2003 |
Potts PR, Singh S, Knezek M, Thompson CB, Deshmukh M. Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis. The Journal of Cell Biology. 163: 789-99. PMID 14623868 DOI: 10.1083/Jcb.200307130 |
0.318 |
|
| 2003 |
D'Sa C, Klocke BJ, Cecconi F, Lindsten T, Thompson CB, Korsmeyer SJ, Flavell RA, Roth KA. Caspase regulation of genotoxin-induced neural precursor cell death. Journal of Neuroscience Research. 74: 435-45. PMID 14598320 DOI: 10.1002/Jnr.10738 |
0.375 |
|
| 2003 |
Edinger AL, Cinalli RM, Thompson CB. Rab7 prevents growth factor-independent survival by inhibiting cell-autonomous nutrient transporter expression. Developmental Cell. 5: 571-82. PMID 14536059 DOI: 10.1016/S1534-5807(03)00291-0 |
0.374 |
|
| 2003 |
Rathmell JC, Fox CJ, Plas DR, Hammerman PS, Cinalli RM, Thompson CB. Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival. Molecular and Cellular Biology. 23: 7315-28. PMID 14517300 DOI: 10.1128/Mcb.23.20.7315-7328.2003 |
0.407 |
|
| 2003 |
Conejo-Garcia JR, Benencia F, Courreges MC, Khang E, Zhang L, Mohamed-Hadley A, Vinocur JM, Buckanovich RJ, Thompson CB, Levine B, Coukos G. Letal, A tumor-associated NKG2D immunoreceptor ligand, induces activation and expansion of effector immune cells. Cancer Biology & Therapy. 2: 446-51. PMID 14508119 DOI: 10.4161/Cbt.2.4.479 |
0.391 |
|
| 2003 |
Carthy CM, Yanagawa B, Luo H, Granville DJ, Yang D, Cheung P, Cheung C, Esfandiarei M, Rudin CM, Thompson CB, Hunt DW, McManus BM. Bcl-2 and Bcl-xL overexpression inhibits cytochrome c release, activation of multiple caspases, and virus release following coxsackievirus B3 infection. Virology. 313: 147-57. PMID 12951029 DOI: 10.1016/S0042-6822(03)00242-3 |
0.516 |
|
| 2003 |
Johnson TR, Stone K, Nikrad M, Yeh T, Zong WX, Thompson CB, Nesterov A, Kraft AS. The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells. Oncogene. 22: 4953-63. PMID 12902978 DOI: 10.1038/Sj.Onc.1206656 |
0.65 |
|
| 2003 |
Rathmell JC, Elstrom RL, Cinalli RM, Thompson CB. Activated Akt promotes increased resting T cell size, CD28-independent T cell growth, and development of autoimmunity and lymphoma. European Journal of Immunology. 33: 2223-32. PMID 12884297 DOI: 10.1002/Eji.200324048 |
0.396 |
|
| 2003 |
Hahn P, Lindsten T, Ying GS, Bennett J, Milam AH, Thompson CB, Dunaief JL. Proapoptotic bcl-2 family members, Bax and Bak, are essential for developmental photoreceptor apoptosis. Investigative Ophthalmology & Visual Science. 44: 3598-605. PMID 12882813 DOI: 10.1167/Iovs.02-1113 |
0.33 |
|
| 2003 |
Fox CJ, Hammerman PS, Cinalli RM, Master SR, Chodosh LA, Thompson CB. The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor. Genes & Development. 17: 1841-54. PMID 12869584 DOI: 10.1101/Gad.1105003 |
0.375 |
|
| 2003 |
Zong WX, Li C, Hatzivassiliou G, Lindsten T, Yu QC, Yuan J, Thompson CB. Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis Journal of Cell Biology. 162: 59-69. PMID 12847083 DOI: 10.1083/Jcb.200302084 |
0.64 |
|
| 2003 |
Tang Q, Smith JA, Szot GL, Zhou P, Alegre ML, Henriksen KJ, Thompson CB, Bluestone JA. CD28/B7 regulation of anti-CD3-mediated immunosuppression in vivo. Journal of Immunology (Baltimore, Md. : 1950). 170: 1510-6. PMID 12538715 DOI: 10.4049/Jimmunol.170.3.1510 |
0.304 |
|
| 2003 |
Plas DR, Thompson CB. Akt activation promotes degradation of tuberin and FOXO3a via the proteasome. The Journal of Biological Chemistry. 278: 12361-6. PMID 12517744 DOI: 10.1074/Jbc.M213069200 |
0.367 |
|
| 2002 |
Li C, Thompson CB. Cancer: DNA damage, deamidation, and death Science. 298: 1346-1347. PMID 12434041 DOI: 10.1126/Science.1079168 |
0.354 |
|
| 2002 |
Rathmell JC, Lindsten T, Zong WX, Cinalli RM, Thompson CB. Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis. Nature Immunology. 3: 932-9. PMID 12244308 DOI: 10.1038/Ni834 |
0.684 |
|
| 2002 |
Vander Heiden MG, Choy JS, VanderWeele DJ, Brace JL, Harris MH, Bauer DE, Prange B, Kron SJ, Thompson CB, Rudin CM. Bcl-x(L) complements Saccharomyces cerevisiae genes that facilitate the switch from glycolytic to oxidative metabolism. The Journal of Biological Chemistry. 277: 44870-6. PMID 12244097 DOI: 10.1074/Jbc.M204888200 |
0.791 |
|
| 2002 |
Gottlieb E, Armour SM, Thompson CB. Mitochondrial respiratory control is lost during growth factor deprivation. Proceedings of the National Academy of Sciences of the United States of America. 99: 12801-6. PMID 12228733 DOI: 10.1073/Pnas.202477599 |
0.355 |
|
| 2002 |
Harlin H, Hwang KW, Palucki DA, Kim O, Thompson CB, Boothby M, Alegre ML. CTLA-4 engagement regulates NF-kappaB activation in vivo. European Journal of Immunology. 32: 2095-104. PMID 12209621 DOI: 10.1002/1521-4141(200208)32:8<2095::Aid-Immu2095>3.0.Co;2-E |
0.745 |
|
| 2002 |
Edinger AL, Thompson CB. Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake. Molecular Biology of the Cell. 13: 2276-88. PMID 12134068 DOI: 10.1091/Mbc.01-12-0584 |
0.402 |
|
| 2002 |
Frauwirth KA, Riley JL, Harris MH, Parry RV, Rathmell JC, Plas DR, Elstrom RL, June CH, Thompson CB. The CD28 signaling pathway regulates glucose metabolism. Immunity. 16: 769-77. PMID 12121659 DOI: 10.1016/S1074-7613(02)00323-0 |
0.382 |
|
| 2002 |
Li C, Fox CJ, Master SR, Bindokas VP, Chodosh LA, Thompson CB. Bcl-X(L) affects Ca(2+) homeostasis by altering expression of inositol 1,4,5-trisphosphate receptors. Proceedings of the National Academy of Sciences of the United States of America. 99: 9830-5. PMID 12118121 DOI: 10.1073/Pnas.152571899 |
0.366 |
|
| 2002 |
Lei K, Nimnual A, Zong WX, Kennedy NJ, Flavell RA, Thompson CB, Bar-Sagi D, Davis RJ. The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase. Molecular and Cellular Biology. 22: 4929-42. PMID 12052897 DOI: 10.1128/Mcb.22.13.4929-4942.2002 |
0.645 |
|
| 2002 |
Plas DR, Rathmell JC, Thompson CB. Homeostatic control of lymphocyte survival: potential origins and implications. Nature Immunology. 3: 515-21. PMID 12032565 DOI: 10.1038/Ni0602-515 |
0.38 |
|
| 2002 |
Rathmell JC, Thompson CB. Pathways of apoptosis in lymphocyte development, homeostasis, and disease. Cell. 109: S97-107. PMID 11983156 DOI: 10.1016/S0092-8674(02)00704-3 |
0.39 |
|
| 2002 |
Putcha GV, Harris CA, Moulder KL, Easton RM, Thompson CB, Johnson EM. Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice. The Journal of Cell Biology. 157: 441-53. PMID 11980919 DOI: 10.1083/Jcb.200110108 |
0.347 |
|
| 2002 |
Arsham AM, Plas DR, Thompson CB, Simon MC. Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription. The Journal of Biological Chemistry. 277: 15162-70. PMID 11859074 DOI: 10.1074/Jbc.M111162200 |
0.362 |
|
| 2002 |
Plas DR, Thompson CB. Cell metabolism in the regulation of programmed cell death. Trends in Endocrinology and Metabolism: Tem. 13: 75-8. PMID 11854022 DOI: 10.1016/S1043-2760(01)00528-8 |
0.419 |
|
| 2002 |
Edinger AL, Thompson CB. Antigen-presenting cells control T cell proliferation by regulating amino acid availability. Proceedings of the National Academy of Sciences of the United States of America. 99: 1107-9. PMID 11830651 DOI: 10.1073/Pnas.042707999 |
0.376 |
|
| 2002 |
Frauwirth KA, Thompson CB. Activation and inhibition of lymphocytes by costimulation. The Journal of Clinical Investigation. 109: 295-9. PMID 11827987 DOI: 10.1172/Jci14941 |
0.374 |
|
| 2002 |
McClintock DS, Santore MT, Lee VY, Brunelle J, Budinger GR, Zong WX, Thompson CB, Hay N, Chandel NS. Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death. Molecular and Cellular Biology. 22: 94-104. PMID 11739725 DOI: 10.1128/Mcb.22.1.94-104.2002 |
0.627 |
|
| 2001 |
Khaled AR, Kim K, Muegge K, Thompson C, Fliegel L, Durum SK. Trophic Factor Withdrawal Induces a Novel Pathway: p38 MAPK Activates NHE1 Resulting in Intracellular Alkalinization, an Early Step in Apoptosis. Thescientificworldjournal. 1: 93. PMID 30147566 DOI: 10.1100/Tsw.2001.211 |
0.395 |
|
| 2001 |
Ross AJ, Amy SP, Mahar PL, Lindsten T, Knudson CM, Thompson CB, Korsmeyer SJ, MacGregor GR. BCLW mediates survival of postmitotic Sertoli cells by regulating BAX activity. Developmental Biology. 239: 295-308. PMID 11784036 DOI: 10.1006/Dbio.2001.0445 |
0.434 |
|
| 2001 |
Rathmell JC, Farkash EA, Gao W, Thompson CB. IL-7 enhances the survival and maintains the size of naive T cells. Journal of Immunology (Baltimore, Md. : 1950). 167: 6869-76. PMID 11739504 DOI: 10.4049/Jimmunol.167.12.6869 |
0.35 |
|
| 2001 |
Hua X, Thompson CB. Quiescent T cells: Actively maintaining inactivity Nature Immunology. 2: 1097-1098. PMID 11725297 DOI: 10.1038/Ni1201-1097 |
0.36 |
|
| 2001 |
Frauwirth KA, Alegre ML, Thompson CB. CTLA-4 is not required for induction of CD8+ T cell anergy in vivo Journal of Immunology. 167: 4936-4941. PMID 11673499 DOI: 10.4049/Jimmunol.167.9.4936 |
0.353 |
|
| 2001 |
Doyle AM, Mullen AC, Villarino AV, Hutchins AS, High FA, Lee HW, Thompson CB, Reiner SL. Induction of cytotoxic T lymphocyte antigen 4 (CTLA-4) restricts clonal expansion of helper T cells. The Journal of Experimental Medicine. 194: 893-902. PMID 11581312 DOI: 10.1084/Jem.194.7.893 |
0.388 |
|
| 2001 |
Vander Heiden MG, Plas DR, Rathmell JC, Fox CJ, Harris MH, Thompson CB. Growth factors can influence cell growth and survival through effects on glucose metabolism Molecular and Cellular Biology. 21: 5899-5912. PMID 11486029 DOI: 10.1128/Mcb.21.17.5899-5912.2001 |
0.588 |
|
| 2001 |
Kaspar AA, Okada S, Kumar J, Poulain FR, Drouvalakis KA, Kelekar A, Hanson DA, Kluck RM, Hitoshi Y, Johnson DE, Froelich CJ, Thompson CB, Newmeyer DD, Anel A, Clayberger C, et al. A distinct pathway of cell-mediated apoptosis initiated by granulysin. Journal of Immunology (Baltimore, Md. : 1950). 167: 350-6. PMID 11418670 DOI: 10.4049/Jimmunol.167.1.350 |
0.307 |
|
| 2001 |
Zong WX, Lindsten T, Ross AJ, MacGregor GR, Thompson CB. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes & Development. 15: 1481-6. PMID 11410528 DOI: 10.1101/Gad.897601 |
0.672 |
|
| 2001 |
Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB, Korsmeyer SJ. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science (New York, N.Y.). 292: 727-30. PMID 11326099 DOI: 10.1126/Science.1059108 |
0.656 |
|
| 2001 |
Harlin H, Reffey SB, Duckett CS, Lindsten T, Thompson CB. Characterization of XIAP-deficient mice. Molecular and Cellular Biology. 21: 3604-8. PMID 11313486 DOI: 10.1128/Mcb.21.10.3604-3608.2001 |
0.753 |
|
| 2001 |
Plas DR, Talapatra S, Edinger AL, Rathmell JC, Thompson CB. Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology. The Journal of Biological Chemistry. 276: 12041-8. PMID 11278698 DOI: 10.1074/Jbc.M010551200 |
0.435 |
|
| 2001 |
Vander Heiden MG, Li XX, Gottleib E, Hill RB, Thompson CB, Colombini M. Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane. The Journal of Biological Chemistry. 276: 19414-9. PMID 11259441 DOI: 10.1074/jbc.M101590200 |
0.626 |
|
| 2001 |
Rudin CM, Thompson CB. Transcriptional activation of short interspersed elements by DNA-damaging agents. Genes, Chromosomes & Cancer. 30: 64-71. PMID 11107177 DOI: 10.1002/1098-2264(2000)9999:9999<::Aid-Gcc1066>3.0.Co;2-F |
0.478 |
|
| 2001 |
Khaled AR, Reynolds DA, Young HA, Thompson CB, Muegge K, Durum SK. Interleukin-3 withdrawal induces an early increase in mitochondrial membrane potential unrelated to the Bcl-2 family. Roles of intracellular pH, ADP transport, and F(0)F(1)-ATPase. The Journal of Biological Chemistry. 276: 6453-62. PMID 11102440 DOI: 10.1074/Jbc.M006391200 |
0.314 |
|
| 2000 |
Harris MH, Thompson CB. The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability Cell Death and Differentiation. 7: 1182-1191. PMID 11175255 DOI: 10.1038/Sj.Cdd.4400781 |
0.363 |
|
| 2000 |
Lindsten T, Ross AJ, King A, Zong WX, Rathmell JC, Shiels HA, Ulrich E, Waymire KG, Mahar P, Frauwirth K, Chen Y, Wei M, Eng VM, Adelman DM, Simon MC, ... ... Thompson CB, et al. The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. Molecular Cell. 6: 1389-99. PMID 11163212 DOI: 10.1016/S1097-2765(00)00136-2 |
0.309 |
|
| 2000 |
Rathmell JC, Vander Heiden MG, Harris MH, Frauwirth KA, Thompson CB. In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability. Molecular Cell. 6: 683-92. PMID 11030347 DOI: 10.1016/S1097-2765(00)00066-6 |
0.624 |
|
| 2000 |
Chuang E, Fisher TS, Morgan RW, Robbins MD, Duerr JM, Vander Heiden MG, Gardner JP, Hambor JE, Neveu MJ, Thompson CB. The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A Immunity. 13: 313-322. PMID 11021529 DOI: 10.1016/S1074-7613(00)00031-5 |
0.558 |
|
| 2000 |
Chandel NS, Vander Heiden MG, Thompson CB, Schumacker PT. Redox regulation of p53 during hypoxia Oncogene. 19: 3840-3848. PMID 10951577 DOI: 10.1038/Sj.Onc.1203727 |
0.605 |
|
| 2000 |
Gottlieb E, Vander Heiden MG, Thompson CB. Bcl-x(L) prevents the initial decrease in mitochondrial membrane potential and subsequent reactive oxygen species production during tumor necrosis factor alpha-induced apoptosis Molecular and Cellular Biology. 20: 5680-5689. PMID 10891504 DOI: 10.1128/Mcb.20.15.5680-5689.2000 |
0.574 |
|
| 2000 |
Arch RH, Gedrich RW, Thompson CB. Translocation of TRAF proteins regulates apoptotic threshold of cells. Biochemical and Biophysical Research Communications. 272: 936-945. PMID 10860854 DOI: 10.1006/Bbrc.2000.2873 |
0.37 |
|
| 2000 |
Masteller EL, Chuang E, Mullen AC, Reiner SL, Thompson CB. Structural analysis of CTLA-4 function in vivo. Journal of Immunology (Baltimore, Md. : 1950). 164: 5319-27. PMID 10799894 DOI: 10.4049/Jimmunol.164.10.5319 |
0.348 |
|
| 2000 |
Vander Heiden MG, Chandel NS, Li XX, Schumacker PT, Colombini M, Thompson CB. Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival. Proceedings of the National Academy of Sciences of the United States of America. 97: 4666-71. PMID 10781072 DOI: 10.1073/Pnas.090082297 |
0.664 |
|
| 2000 |
Harris MH, Vander Heiden MG, Kron SJ, Thompson CB. Role of oxidative phosphorylation in Bax toxicity Molecular and Cellular Biology. 20: 3590-3596. PMID 10779348 DOI: 10.1128/Mcb.20.10.3590-3596.2000 |
0.588 |
|
| 2000 |
Frauwirth KA, Alegre ML, Thompson CB. Induction of T cell anergy in the absence of CTLA-4/B7 interaction Journal of Immunology. 164: 2987-2993. PMID 10706686 DOI: 10.4049/Jimmunol.164.6.2987 |
0.348 |
|
| 2000 |
Zhou YP, Pena JC, Roe MW, Mittal A, Levisetti M, Baldwin AC, Pugh W, Ostrega D, Ahmed N, Bindokas VP, Philipson LH, Hanahan D, Thompson CB, Polonsky KS. Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 278: E340-51. PMID 10662719 DOI: 10.1152/Ajpendo.2000.278.2.E340 |
0.325 |
|
| 2000 |
Schor NF, Rudin CM, Hartman AR, Thompson CB, Tyurina YY, Kagan VE. Cell line dependence of Bcl-2-induced alteration of glutathione handling. Oncogene. 19: 472-6. PMID 10656697 DOI: 10.1038/sj.onc.1203324 |
0.485 |
|
| 2000 |
Wei MC, Lindsten T, Mootha VK, Weiler S, Gross A, Ashiya M, Thompson CB, Korsmeyer SJ. tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c Genes & Development. 14: 2060-2071. DOI: 10.1101/Gad.14.16.2060 |
0.32 |
|
| 1999 |
Thompson CB, Rathmell JC, Frauwirth KA, Lindsten T, Rudin CM, Opferman JT, Ashton-Rickardt PG, Harris MH, Chandel NS, Schumacker PT, Vander Heiden MG. What keeps a resting T cell alive? Cold Spring Harbor Symposia On Quantitative Biology. 64: 383-7. PMID 11232311 DOI: 10.1101/Sqb.1999.64.383 |
0.705 |
|
| 1999 |
Arch RH, Thompson CB. Lymphocyte survival - The struggle against death Annual Review of Cell and Developmental Biology. 15: 113-140. PMID 10611959 DOI: 10.1146/Annurev.Cellbio.15.1.113 |
0.405 |
|
| 1999 |
Vander Heiden MG, Thompson CB. Bcl-2 proteins: Regulators of apoptosis or of mitochondrial homeostasis? Nature Cell Biology. 1: E209-E216. PMID 10587660 |
0.543 |
|
| 1999 |
Chang BS, Kelekar A, Harris MH, Harlan JE, Fesik SW, Thompson CB. The BH3 domain of Bcl-x(S) is required for inhibition of the antiapoptotic function of Bcl-x(L). Molecular and Cellular Biology. 19: 6673-81. PMID 10490606 DOI: 10.1128/Mcb.19.10.6673 |
0.333 |
|
| 1999 |
Pena JC, Kelekar A, Fuchs EV, Thompson CB. Manipulation of outer root sheath cell survival perturbs the hair-growth cycle. The Embo Journal. 18: 3596-603. PMID 10393176 DOI: 10.1093/Emboj/18.13.3596 |
0.394 |
|
| 1999 |
Rathmell JC, Thompson CB. The central effectors of cell death in the immune system Annual Review of Immunology. 17: 781-828. PMID 10358774 DOI: 10.1146/Annurev.Immunol.17.1.781 |
0.395 |
|
| 1999 |
Vander Heiden MG, Chandel NS, Schumacker PT, Thompson CB. Bcl-x(L) prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange Molecular Cell. 3: 159-167. PMID 10078199 DOI: 10.1016/S1097-2765(00)80307-X |
0.583 |
|
| 1999 |
Burri SH, Kim CN, Fang G, Chang BS, Perkins C, Harris W, Davis LW, Thompson CB, Bhalla KN. 'Loop' domain deletional mutant of Bcl-xL is as effective as p29Bcl-xL in inhibiting radiation-induced cytosolic accumulation of cytochrome c (cyt c), caspase-3 activity, and apoptosis. International Journal of Radiation Oncology, Biology, Physics. 43: 423-30. PMID 10030271 DOI: 10.1016/S0360-3016(98)00385-X |
0.417 |
|
| 1999 |
Minn AJ, Kettlun CS, Liang H, Kelekar A, Vander Heiden MG, Chang BS, Fesik SW, Fill M, Thompson CB. Bcl-x(L) regulates apoptosis by heterodimerization-dependent and -independent mechanisms Embo Journal. 18: 632-643. PMID 9927423 DOI: 10.1093/Emboj/18.3.632 |
0.611 |
|
| 1999 |
Pena JC, Thompson CB, Recant W, Vokes EE, Rudin CM. Bcl-xL and Bcl-2 expression in squamous cell carcinoma of the head and neck. Cancer. 85: 164-70. PMID 9921989 DOI: 10.1002/(SICI)1097-0142(19990101)85:1<164::AID-CNCR23>3.0.CO;2-Q |
0.461 |
|
| 1999 |
Thompson CB, Heiden MV, Chang BS, Minn AJ, Sattler M, Liang H, Muchmore SW, Fesik SW. Role of Bcl-2 family members in apoptotic cell death Kidney International. 56: 1192. DOI: 10.1046/J.1523-1755.1999.0560041192.X |
0.303 |
|
| 1998 |
Dragovich T, Rudin CM, Thompson CB. Signal transduction pathways that regulate cell survival and cell death. Oncogene. 17: 3207-13. PMID 9916983 DOI: 10.1038/Sj.Onc.1202587 |
0.555 |
|
| 1998 |
Lee KM, Chuang E, Griffin M, Khattri R, Hong DK, Zhang W, Straus D, Samelson LE, Thompson CB, Bluestone JA. Molecular Basis of T Cell Inactivation by CTLA-4 Science. 282: 2263-2266. PMID 9856951 DOI: 10.1126/Science.282.5397.2263 |
0.367 |
|
| 1998 |
Haughn L, Leung B, Boise L, Veillette A, Thompson C, Julius M. Interleukin 2-mediated uncoupling of T cell receptor alpha/beta from CD3 signaling. The Journal of Experimental Medicine. 188: 1575-86. PMID 9802969 DOI: 10.1084/Jem.188.9.1575 |
0.322 |
|
| 1998 |
Minn AJ, Swain RE, Ma A, Thompson CB. Recent progress on the regulation of apoptosis by Bcl-2 family members. Advances in Immunology. 70: 245-79. PMID 9755339 DOI: 10.1016/S0065-2776(08)60388-0 |
0.368 |
|
| 1998 |
Arch RH, Gedrich RW, Thompson CB. Tumor necrosis factor receptor-associated factors (TRAFs)—a family of adapter proteins that regulates life and death Genes & Development. 12: 2821-2830. PMID 9744859 DOI: 10.1101/Gad.12.18.2821 |
0.37 |
|
| 1998 |
Noel PJ, Alegre ML, Reiner SL, Thompson CB. Impaired negative selection in CD28-deficient mice Cellular Immunology. 187: 131-138. PMID 9732701 DOI: 10.1006/Cimm.1998.1332 |
0.324 |
|
| 1998 |
Kelekar A, Thompson CB. Bcl-2-family proteins: The role of the BH3 domain in apoptosis Trends in Cell Biology. 8: 324-330. PMID 9704409 DOI: 10.1016/S0962-8924(98)01321-X |
0.323 |
|
| 1998 |
Dolan ME, Frydman B, Thompson CB, Diamond AM, Garbiras BJ, Safa AR, Beck WT, Marton LJ. Effects of 1,2-naphthoquinones on human tumor cell growth and lack of cross-resistance with other anticancer agents. Anti-Cancer Drugs. 9: 437-48. PMID 9660542 DOI: 10.1097/00001813-199806000-00011 |
0.348 |
|
| 1998 |
Funk PE, Thompson CB. Identification of a lectin that induces cell death in developing chicken B cells Cellular Immunology. 186: 75-81. PMID 9637767 DOI: 10.1006/Cimm.1998.1306 |
0.396 |
|
| 1998 |
Sanna MG, Duckett CS, Richter BW, Thompson CB, Ulevitch RJ. Selective activation of JNK1 is necessary for the anti-apoptotic activity of hILP. Proceedings of the National Academy of Sciences of the United States of America. 95: 6015-20. PMID 9600909 DOI: 10.1073/Pnas.95.11.6015 |
0.362 |
|
| 1998 |
Markiewicz MA, Girao C, Opferman JT, Sun J, Hu Q, Agulnik AA, Bishop CE, Thompson CB, Ashton-Rickardt PG. Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules. Proceedings of the National Academy of Sciences of the United States of America. 95: 3065-70. PMID 9501216 DOI: 10.1073/Pnas.95.6.3065 |
0.321 |
|
| 1998 |
Duckett CS, Li F, Wang Y, Tomaselli KJ, Thompson CB, Armstrong RC. Human IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome c. Molecular and Cellular Biology. 18: 608-15. PMID 9418907 DOI: 10.1128/Mcb.18.1.608 |
0.396 |
|
| 1998 |
Arch RH, Thompson CB. 4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor κB Molecular and Cellular Biology. 18: 558-565. PMID 9418902 DOI: 10.1128/Mcb.18.1.558 |
0.303 |
|
| 1997 |
Vander Heiden MG, Chandel NS, Williamson EK, Schumacker PT, Thompson CB. Bcl-x(L) regulates the membrane potential and volume homeostasis of mitochondria Cell. 91: 627-637. PMID 9393856 DOI: 10.1016/S0092-8674(00)80450-X |
0.568 |
|
| 1997 |
Kelekar A, Chang BS, Harlan JE, Fesik SW, Thompson CB. Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL Molecular and Cellular Biology. 17: 7040-7046. PMID 9372935 DOI: 10.1128/Mcb.17.12.7040 |
0.388 |
|
| 1997 |
Duckett CS, Thompson CB. CD30-dependent degradation of TRAF2: Implications for negative regulation of TRAF signaling and the control of cell survival Genes and Development. 11: 2810-2821. PMID 9353251 DOI: 10.1101/Gad.11.21.2810 |
0.357 |
|
| 1997 |
Van Houten N, Blake SF, Li EJ, Hallam TA, Chilton DG, Gourley WK, Boise LH, Thompson CB, Thompson EB. Elevated expression of Bcl-2 and Bcl-x by intestinal intraepithelial lymphocytes: resistance to apoptosis by glucocorticoids and irradiation. International Immunology. 9: 945-53. PMID 9237103 DOI: 10.1093/Intimm/9.7.945 |
0.375 |
|
| 1997 |
Chuang E, Alegre ML, Duckett CS, Noel PJ, Vander Heiden MG, Thompson CB. Interaction of CTLA-4 with the Clathrin-Associated Protein AP50 Results in Ligand-Independent Endocytosis That Limits Cell Surface Expression Journal of Immunology. 159: 144-151. PMID 9200449 |
0.534 |
|
| 1997 |
Blair PJ, Boise LH, Perfetto SP, Levine BL, McCrary G, Wagner KF, St Louis DC, Thompson CB, Siegel JN, June CH. Impaired induction of the apoptosis-protective protein Bcl-xL in activated PBMC from asymptomatic HIV-infected individuals. Journal of Clinical Immunology. 17: 234-46. PMID 9168404 DOI: 10.1023/A:1027310612323 |
0.332 |
|
| 1997 |
Chang BS, Minn AJ, Muchmore SW, Fesik SW, Thompson CB. Identification of a novel regulatory domain in Bcl‐xL and Bcl‐2 The Embo Journal. 16: 968-977. PMID 9118958 DOI: 10.1093/Emboj/16.5.968 |
0.391 |
|
| 1997 |
Boise LH, Thompson CB. Bcl-x(L) can inhibit apoptosis in cells that have undergone Fas-induced protease activation Proceedings of the National Academy of Sciences of the United States of America. 94: 3759-3764. PMID 9108051 DOI: 10.1073/Pnas.94.8.3759 |
0.408 |
|
| 1997 |
Rudin CM, Thompson CB. Apoptosis and disease: regulation and clinical relevance of programmed cell death. Annual Review of Medicine. 48: 267-81. PMID 9046961 DOI: 10.1146/Annurev.Med.48.1.267 |
0.547 |
|
| 1997 |
Sattler M, Liang H, Nettesheim D, Meadows RP, Harlan JE, Eberstadt M, Yoon HS, Shuker SB, Chang BS, Minn AJ, Thompson CB, Fesik SW. Structure of Bcl-x(L)-Bak peptide complex: Recognition between regulators of apoptosis Science. 275: 983-986. PMID 9020082 DOI: 10.1126/Science.275.5302.983 |
0.32 |
|
| 1997 |
Noel PJ, Boise LH, Thompson CB. Regulation of T cell activation by CD28 and CTLA4. Advances in Experimental Medicine and Biology. 406: 209-17. PMID 8910687 DOI: 10.1007/978-1-4899-0274-0_22 |
0.445 |
|
| 1996 |
Rudin CM, Van Dongen J, Thompson CB. Apoptotic signaling in lymphocytes. Current Opinion in Hematology. 3: 35-40. PMID 9372049 DOI: 10.1097/00062752-199603010-00006 |
0.54 |
|
| 1996 |
Lee KP, Carlson LM, Woodcock JB, Ramachandra N, Schultz TL, Davis TA, Lowe JB, Thompson CB, Larsen RD. Molecular cloning and characterization of CFT1, a developmentally regulated avian alpha(1,3)-fucosyltransferase gene. The Journal of Biological Chemistry. 271: 32960-7. PMID 8955139 DOI: 10.1074/Jbc.271.51.32960 |
0.338 |
|
| 1996 |
Gajewski TF, Thompson CB. Apoptosis meets signal transduction: Elimination of a BAD influence Cell. 87: 589-592. PMID 8929527 DOI: 10.1016/S0092-8674(00)81377-X |
0.403 |
|
| 1996 |
Zhang X, Li L, Choe J, Krajewski S, Reed JC, Thompson C, Choi YS. Up-regulation of Bcl-xL expression protects CD40-activated human B cells from Fas-mediated apoptosis. Cellular Immunology. 173: 149-154. PMID 8871610 DOI: 10.1006/Cimm.1996.0260 |
0.399 |
|
| 1996 |
Eves EM, Boise LH, Thompson CB, Wagner AJ, Hay N, Rosner MR. Apoptosis induced by differentiation or serum deprivation in an immortalized central nervous system neuronal cell line Journal of Neurochemistry. 67: 1908-1920. PMID 8863495 DOI: 10.1046/J.1471-4159.1996.67051908.X |
0.423 |
|
| 1996 |
Boise LH, Thompson CB. Hierarchical control of lymphocyte survival Science. 274: 67-68. PMID 8848725 DOI: 10.1126/Science.274.5284.67 |
0.303 |
|
| 1996 |
Muchmore SW, Sattler M, Liang H, Meadows RP, Harlan JE, Yoon HS, Nettesheim D, Chang BS, Thompson CB, Wong SL, Ng SL, Fesik SW. X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature. 381: 335-41. PMID 8692274 DOI: 10.1038/381335A0 |
0.313 |
|
| 1996 |
Boise LH, McShan CL, Thompson CB. Introduction of the cell survival gene bcl-xL improves the viability of CTLL-2 cells without affecting their IL-2 proliferative response. Implications for the development of bioassays. Journal of Immunological Methods. 191: 143-8. PMID 8666833 DOI: 10.1016/0022-1759(96)00011-7 |
0.338 |
|
| 1996 |
Green JM, Thompson CB. Homotypic interactions mediated through LFA-1/ICAM-3 decrease the proliferative response of activated T cells Cellular Immunology. 171: 126-131. PMID 8660847 DOI: 10.1006/Cimm.1996.0182 |
0.363 |
|
| 1996 |
Grillot DAM, Merino R, Pena JC, Fanslow WC, Finkelman FD, Thompson CB, Núñez G. bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice. Journal of Experimental Medicine. 183: 381-391. PMID 8627151 DOI: 10.1084/Jem.183.2.381 |
0.391 |
|
| 1996 |
Minn AJ, Boise LH, Thompson CB. Bcl-x(S) anatagonizes the protective effects of Bcl-x(L). The Journal of Biological Chemistry. 271: 6306-12. PMID 8626425 DOI: 10.1074/Jbc.271.11.6306 |
0.309 |
|
| 1996 |
Cheng EH, Levine B, Boise LH, Thompson CB, Hardwick JM. Bax-independent inhibition of apoptosis by Bcl-XL. Nature. 379: 554-6. PMID 8596636 DOI: 10.1038/379554A0 |
0.364 |
|
| 1996 |
Boise LH, Noel PJ, Thompson CB. CD28 and apoptosis. Current Opinion in Immunology. 7: 620-5. PMID 8573303 DOI: 10.1016/0952-7915(95)80067-0 |
0.378 |
|
| 1996 |
Duckett CS, Nava VE, Gedrich RW, Clem RJ, Van Dongen JL, Gilfillan MC, Shiels H, Hardwick JM, Thompson CB. A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors. The Embo Journal. 15: 2685-2694. DOI: 10.1002/J.1460-2075.1996.Tb00629.X |
0.403 |
|
| 1995 |
Thompson CB. Apoptosis in the pathogenesis and treatment of disease Science. 267: 1456-1462. PMID 7878464 DOI: 10.1126/Science.7878464 |
0.408 |
|
| 1995 |
John S, Reeves RB, Lin JX, Child R, Leiden JM, Thompson CB, Leonard WJ. Regulation of cell-type-specific interleukin-2 receptor alpha-chain gene expression: potential role of physical interactions between Elf-1, HMG-I(Y), and NF-kappa B family proteins. Molecular and Cellular Biology. 15: 1786-96. PMID 7862168 DOI: 10.1128/Mcb.15.3.1786 |
0.346 |
|
| 1995 |
Yang E, Zha J, Jockel J, Boise LH, Thompson CB, Korsmeyer SJ. Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death. Cell. 80: 285-91. PMID 7834748 DOI: 10.1016/0092-8674(95)90411-5 |
0.376 |
|
| 1995 |
Sperling AI, Green JM, Mosley RL, Smith PL, DiPaolo RJ, Klein JR, Bluestone JA, Thompson CB. CD43 is a murine T cell costimulatory receptor that functions independently of CD28. The Journal of Experimental Medicine. 182: 139-46. PMID 7790813 DOI: 10.1084/Jem.182.1.139 |
0.309 |
|
| 1995 |
Boise LH, Minn AJ, June CH, Lindsten T, Thompson CB. Growth factors can enhance lymphocyte survival without committing the cell to undergo cell division. Proceedings of the National Academy of Sciences of the United States of America. 92: 5491-5. PMID 7777536 DOI: 10.1073/Pnas.92.12.5491 |
0.314 |
|
| 1995 |
Ma A, Pena JC, Chang B, Margosian E, Davidson L, Alt FW, Thompson CB. Bclx regulates the survival of double-positive thymocytes. Proceedings of the National Academy of Sciences of the United States of America. 92: 4763-7. PMID 7761398 DOI: 10.1073/Pnas.92.11.4763 |
0.34 |
|
| 1995 |
González-García M, García I, Ding L, O'Shea S, Boise LH, Thompson CB, Núñez G. bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death. Proceedings of the National Academy of Sciences of the United States of America. 92: 4304-8. PMID 7753802 DOI: 10.1073/Pnas.92.10.4304 |
0.301 |
|
| 1995 |
Sedlak TW, Oltvai ZN, Yang E, Wang K, Boise LH, Thompson CB, Korsmeyer SJ. Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proceedings of the National Academy of Sciences of the United States of America. 92: 7834-8. PMID 7644501 DOI: 10.1073/Pnas.92.17.7834 |
0.359 |
|
| 1995 |
Boise LH, Gottschalk AR, Quintans J, Thompson CB. Bcl-2 and Bcl-2-related proteins in apoptosis regulation Current Topics in Microbiology and Immunology. 200: 107-121. PMID 7634826 DOI: 10.1007/978-3-642-79437-7_8 |
0.38 |
|
| 1995 |
Boise LH, Minn AJ, Noel PJ, June CH, Accavitti MA, Lindsten T, Thompson CB. CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity. 3: 87-98. PMID 7621080 DOI: 10.1016/1074-7613(95)90161-2 |
0.371 |
|
| 1995 |
Choi MSK, Boise LH, Gottschalk AR, Quintans J, Thompson CB, Klaus GGB. The role of bcl-xL in CD40-mediated rescue from anti-μ-induced apoptosis in WEHI-231 B lymphoma cells European Journal of Immunology. 25: 1352-1357. PMID 7539757 DOI: 10.1002/Eji.1830250533 |
0.384 |
|
| 1995 |
Green JM, Noel PJ, Sperling AI, Walunas TL, Gray GS, Bluestone JA, Thompson CB. Absence of B7-dependent responses in CD28-deficient mice. Immunity. 1: 501-8. PMID 7534617 DOI: 10.1016/1074-7613(94)90092-2 |
0.328 |
|
| 1995 |
Boise LH, Minn AJ, Thompson CB. Receptors that regulate T-cell susceptibility to apoptotic cell death. Annals of the New York Academy of Sciences. 766: 70-80. PMID 7486701 DOI: 10.1111/J.1749-6632.1995.Tb26650.X |
0.398 |
|
| 1995 |
Waterhouse P, Penninger JM, Timms E, Wakeham A, Shahinian A, Lee KP, Thompson CB, Griesser H, Mak TW. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science (New York, N.Y.). 270: 985-8. PMID 7481803 DOI: 10.1126/Science.270.5238.985 |
0.378 |
|
| 1995 |
Clarke MF, Apel IJ, Benedict MA, Eipers PG, Sumantran V, González-García M, Doedens M, Fukunaga N, Davidson B, Dick JE, Minn AJ, Boise LH, Thompson CB, Wicha M, Núñez G. A recombinant bcl-x s adenovirus selectively induces apoptosis in cancer cells but not in normal bone marrow cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 11024-8. PMID 7479929 DOI: 10.1073/Pnas.92.24.11024 |
0.39 |
|
| 1995 |
Minn A, Rudin C, Boise L, Thompson C. Expression of bcl-xL can confer a multidrug resistance phenotype Blood. 86: 1903-1910. DOI: 10.1182/Blood.V86.5.1903.Bloodjournal8651903 |
0.578 |
|
| 1994 |
Nickoloff BJ, Mitra RS, Green J, Shimizu Y, Thompson C, Turka LA. Activated keratinocytes present bacterial-derived superantigens to T lymphocytes: relevance to psoriasis. Journal of Dermatological Science. 6: 127-33. PMID 8274458 DOI: 10.1016/0923-1811(93)90002-7 |
0.3 |
|
| 1994 |
Masteller EL, Thompson CB. B cell development in the chicken Poultry Science. 73: 998-1011. PMID 7937489 DOI: 10.3382/Ps.0730998 |
0.358 |
|
| 1994 |
Leiden JM, Thompson CB. Transcriptional regulation of T-cell genes during T-cell development. Current Opinion in Immunology. 6: 231-7. PMID 7912079 DOI: 10.1016/0952-7915(94)90096-5 |
0.366 |
|
| 1994 |
Walunas TL, Lenschow DJ, Bakker CY, Linsley PS, Freeman GJ, Green JM, Thompson CB, Bluestone JA. CTLA-4 can function as a negative regulator of T cell activation Immunity. 1: 405-413. PMID 7882171 DOI: 10.1016/1074-7613(94)90071-X |
0.354 |
|
| 1994 |
Green JM, Thompson CB. Modulation of T cell proliferative responses by accessory cell interactions Immunologic Research. 13: 234-243. PMID 7616051 DOI: 10.1007/Bf02935615 |
0.351 |
|
| 1994 |
Page C, Thompson C, Yacoub M, Rose M. Human endothelial stimulation of allogeneic T cells via a CTLA-4 independent pathway. Transplant Immunology. 2: 342-347. PMID 7535644 DOI: 10.1016/0966-3274(94)90013-2 |
0.358 |
|
| 1994 |
June CH, Bluestone JA, Nadler LM, Thompson CB. The B7 and CD28 receptor families. Immunology Today. 15: 321-31. PMID 7522010 DOI: 10.1016/0167-5699(94)90080-9 |
0.321 |
|
| 1994 |
Gottschalk AR, Boise LH, Thompson CB, Quintáns J. Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2 Proceedings of the National Academy of Sciences of the United States of America. 91: 7350-7354. PMID 7518929 DOI: 10.1073/Pnas.91.15.7350 |
0.438 |
|
| 1994 |
Green JM, Zheng XG, Shimizu Y, Thompson CB, Turka LA. T cell receptor stimulation, but not CD28 costimulation, is dependent on LFA-1-mediated events. European Journal of Immunology. 24: 265-72. PMID 7517362 DOI: 10.1002/Eji.1830240141 |
0.331 |
|
| 1994 |
Nestle FO, Thompson C, Shimizu Y, Turka LA, Nickoloff BJ. Costimulation of superantigen-activated T lymphocytes by autologous dendritic cells is dependent on B7. Cellular Immunology. 156: 220-9. PMID 7515331 DOI: 10.1006/Cimm.1994.1166 |
0.346 |
|
| 1993 |
Wang CY, Petryniak B, Thompson CB, Kaelin WG, Leiden JM. Regulation of the Ets-related transcription factor Elf-1 by binding to the retinoblastoma protein. Science (New York, N.Y.). 260: 1330-5. PMID 8493578 DOI: 10.1126/Science.8493578 |
0.391 |
|
| 1993 |
Boise LH, Petryniak B, Mao X, June CH, Wang CY, Lindsten T, Bravo R, Kovary K, Leiden JM, Thompson CB. The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB. Molecular and Cellular Biology. 13: 1911-9. PMID 8441422 DOI: 10.1128/Mcb.13.3.1911 |
0.337 |
|
| 1993 |
Pickel JM, McCormack WT, Chen CH, Cooper MD, Thompson CB. Differential regulation of V(D)J recombination during development of avian B and T cells. International Immunology. 5: 919-27. PMID 8398986 DOI: 10.1093/Intimm/5.8.919 |
0.349 |
|
| 1993 |
Boise LH, González-García M, Postema CE, Ding L, Lindsten T, Turka LA, Mao X, Nuñez G, Thompson CB. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell. 74: 597-608. PMID 8358789 DOI: 10.1016/0092-8674(93)90508-N |
0.419 |
|
| 1993 |
Mitchell BS, Dayton JS, Turka LA, Thompson CB. IMP Dehydrogenase Inhibitors as Immunomodulators Annals of the New York Academy of Sciences. 685: 217-224. PMID 8103312 DOI: 10.1111/J.1749-6632.1993.Tb35869.X |
0.37 |
|
| 1993 |
Shahinian A, Pfeffer K, Lee KP, Kündig TM, Kishihara K, Wakeham A, Kawai K, Ohashi PS, Thompson CB, Mak TW. Differential T cell costimulatory requirements in CD28-deficient mice Science. 261: 609-612. PMID 7688139 DOI: 10.1126/Science.7688139 |
0.316 |
|
| 1992 |
Thompson CB, Wang CY, Ho IC, Bohjanen PR, Petryniak B, June CH, Miesfeldt S, Zhang L, Nabel GJ, Karpinski B, Leiden JM. cis-Acting Sequences Required for Inducible Interleukin-2 Enhancer Function Bind a Novel Ets-Related Protein, Elf-1 Molecular and Cellular Biology. 12: 1043-1053. PMID 1545787 DOI: 10.1128/Mcb.12.3.1043 |
0.335 |
|
| 1992 |
Vandenberghe P, Freeman GJ, Nadler LM, Fletcher MC, Kamoun M, Turka LA, Ledbetter JA, Thompson CB, June CH. Antibody and B7/BB1-mediated ligation of the CD28 receptor induces tyrosine phosphorylation in human T cells. The Journal of Experimental Medicine. 175: 951-60. PMID 1372649 DOI: 10.1084/Jem.175.4.951 |
0.33 |
|
| 1992 |
Green JM, Turka LA, June CH, Thompson CB. CD28 and staphylococcal enterotoxins synergize to induce MHC-independent T-cell proliferation. Cellular Immunology. 145: 11-20. PMID 1330329 DOI: 10.1016/0008-8749(92)90308-C |
0.359 |
|
| 1992 |
Thompson CB. RAG knockouts deliver a one/two punch Current Biology. 2: 180-182. DOI: 10.1016/0960-9822(92)90506-6 |
0.348 |
|
| 1991 |
Turka LA, Dayton J, Sinclair G, Thompson CB, Mitchell BS. Guanine ribonucleotide depletion inhibits T cell activation. Mechanism of action of the immunosuppressive drug mizoribine. The Journal of Clinical Investigation. 87: 940-8. PMID 1999502 DOI: 10.1172/Jci115101 |
0.375 |
|
| 1991 |
Carlson LM, Oettinger MA, Schatz DG, Masteller EL, Hurley EA, McCormack WT, Baltimore D, Thompson CB. Selective expression of RAG-2 in chicken B cells undergoing immunoglobulin gene conversion. Cell. 64: 201-8. PMID 1986866 DOI: 10.1016/0092-8674(91)90221-J |
0.325 |
|
| 1991 |
Cooper MD, Chen CL, Bucy RP, Thompson CB. Avian T cell ontogeny. Advances in Immunology. 50: 87-117. PMID 1835268 DOI: 10.1016/S0065-2776(08)60823-8 |
0.34 |
|
| 1991 |
Turka LA, Schatz DG, Oettinger MA, Chun JJ, Gorka C, Lee K, McCormack WT, Thompson CB. Thymocyte expression of RAG-1 and RAG-2: termination by T cell receptor cross-linking. Science (New York, N.Y.). 253: 778-81. PMID 1831564 DOI: 10.1126/Science.1831564 |
0.304 |
|
| 1990 |
Guba SC, Stella G, Turka LA, June CH, Thompson CB, Emerson SG. Regulation of interleukin 3 gene induction in normal human T cells. The Journal of Clinical Investigation. 84: 1701-6. PMID 2556442 DOI: 10.1172/Jci114352 |
0.311 |
|
| 1990 |
June CH, Ledbetter JA, Linsley PS, Thompson CB. Role of the CD28 receptor in T-cell activation. Immunology Today. 11: 211-6. PMID 2162180 DOI: 10.1016/0167-5699(90)90085-N |
0.356 |
|
| 1990 |
McCormack WT, Thompson CB. Somatic diversification of the chicken immunoglobulin light-chain gene Advances in Immunology. 48: 41-67. PMID 2112303 DOI: 10.1016/S0065-2776(08)60751-8 |
0.325 |
|
| 1990 |
Kim S, Humphries EH, Tjoelker L, Carlson L, Thompson CB. Ongoing diversification of the rearranged immunoglobulin light-chain gene in a bursal lymphoma cell line. Molecular and Cellular Biology. 10: 3224-31. PMID 2111450 DOI: 10.1128/Mcb.10.6.3224 |
0.304 |
|
| 1990 |
Elder JT, Forrester WC, Thompson C, Mager D, Henthorn P, Peretz M, Papayannopoulou T, Groudine M. Translocation of an erythroid-specific hypersensitive site in deletion-type hereditary persistence of fetal hemoglobin. Molecular and Cellular Biology. 10: 1382-9. PMID 1690839 DOI: 10.1128/mcb.10.4.1382-1389.1990 |
0.323 |
|
| 1989 |
Parmacek MS, Karpinski BA, Gottesdiener KM, Thompson CB, Leiden JM. Structure, expression and regulation of the murine 4F2 heavy chain. Nucleic Acids Research. 17: 1915-31. PMID 2928113 DOI: 10.1093/Nar/17.5.1915 |
0.329 |
|
| 1989 |
Leiden JM, Yang LH, Morle GD, June CH, Lindsten T, Thompson CB, Karpinski B. The 4F2 heavy chain gene: a molecular model of inducible gene expression in human T cells. Journal of Autoimmunity. 2: 67-79. PMID 2789062 DOI: 10.1016/0896-8411(89)90118-2 |
0.369 |
|
| 1989 |
June CH, Jackson KM, Ledbetter JA, Leiden JM, Lindsten T, Thompson CB. Two distinct mechanisms of interleukin-2 gene expression in human T lymphocytes. Journal of Autoimmunity. 2: 55-65. PMID 2550020 DOI: 10.1016/0896-8411(89)90117-0 |
0.309 |
|
| 1989 |
Lindstein T, June CH, Ledbetter JA, Stella G, Thompson CB. Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway. Science (New York, N.Y.). 244: 339-43. PMID 2540528 DOI: 10.1126/Science.2540528 |
0.339 |
|
| 1989 |
McCormack WT, Tjoelker LW, Barth CF, Carlson LM, Petryniak B, Humphries EH, Thompson CB. Selection for B cells with productive IgL gene rearrangements occurs in the bursa of Fabricius during chicken embryonic development. Genes & Development. 3: 838-47. PMID 2501152 DOI: 10.1101/Gad.3.6.838 |
0.312 |
|
| 1989 |
Thompson CB, Lindsten T, Ledbetter JA, Kunkel SL, Young HA, Emerson SG, Leiden JM, June CH. CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines. Proceedings of the National Academy of Sciences of the United States of America. 86: 1333-7. PMID 2465550 DOI: 10.1073/Pnas.86.4.1333 |
0.34 |
|
| 1988 |
Lindsten T, June CH, Thompson CB, Leiden JM. Regulation of 4F2 heavy-chain gene expression during normal human T-cell activation can be mediated by multiple distinct molecular mechanisms. Molecular and Cellular Biology. 8: 3820-6. PMID 3265471 DOI: 10.1128/Mcb.8.9.3820 |
0.379 |
|
| 1988 |
Gottesdiener KM, Karpinski BA, Lindsten T, Strominger JL, Jones NH, Thompson CB, Leiden JM. Isolation and structural characterization of the human 4F2 heavy-chain gene, an inducible gene involved in T-lymphocyte activation. Molecular and Cellular Biology. 8: 3809-19. PMID 3265470 DOI: 10.1128/Mcb.8.9.3809 |
0.337 |
|
| 1988 |
Lindsten T, June CH, Thompson CB. Stimulation of the antigen receptor complex leads to transcriptional activation of the c-myc gene in normal human T cells Current Topics in Microbiology and Immunology. 141: 223-230. PMID 3265089 DOI: 10.1007/978-3-642-74006-0_30 |
0.324 |
|
| 1988 |
Bender TP, Catron KM, Kuehl WM, Thompson CB. Sense and anti-sense transcription in the murine c-myb attenuator region. Current Topics in Microbiology and Immunology. 141: 324-9. PMID 2463898 DOI: 10.1007/978-3-642-74006-0_43 |
0.344 |
|
| 1988 |
Lindsten T, June CH, Thompson CB. Multiple mechanisms regulate c-myc gene expression during normal T cell activation. The Embo Journal. 7: 2787-2794. DOI: 10.1002/J.1460-2075.1988.Tb03133.X |
0.362 |
|
| 1987 |
Thompson CB, Humphries EH, Carlson LM, Chen CL, Neiman PE. The effect of alterations in myc gene expression on B cell development in the bursa of Fabricius. Cell. 51: 371-81. PMID 3499231 DOI: 10.1016/0092-8674(87)90633-7 |
0.378 |
|
| 1987 |
Bender TP, Thompson CB, Kuehl WM. Differential expression of c-myb mRNA in murine B lymphomas by a block to transcription elongation. Science (New York, N.Y.). 237: 1473-6. PMID 3498214 DOI: 10.1126/Science.3498214 |
0.333 |
|
| 1987 |
June CH, Ledbetter JA, Gillespie MM, Lindsten T, Thompson CB. T-cell proliferation involving the CD28 pathway is associated with cyclosporine-resistant interleukin 2 gene expression. Molecular and Cellular Biology. 7: 4472-81. PMID 2830495 DOI: 10.1128/Mcb.7.12.4472 |
0.328 |
|
| 1986 |
Thompson CB, Sanders JE, Flournoy N, Buckner CD, Thomas ED. The risks of central nervous system relapse and leukoencephalopathy in patients receiving marrow transplants for acute leukemia. Blood. 67: 195-9. PMID 3510066 DOI: 10.1182/Blood.V67.1.195.195 |
0.31 |
|
| 1985 |
June CH, Thompson CB, Kennedy MS, Nims J, Thomas ED. Profound hypomagnesemia and renal magnesium wasting associated with the use of cyclosporine for marrow transplantation. Transplantation. 39: 620-4. PMID 3890292 DOI: 10.1097/00007890-198506000-00009 |
0.403 |
|
| 1985 |
Mond JJ, Thompson C, Finkelman FD, Farrar J, Schaefer M, Robb RJ. Affinity-purified interleukin 2 induces proliferation of large but not small B cells. Proceedings of the National Academy of Sciences of the United States of America. 82: 1518-1521. PMID 3871950 DOI: 10.1073/Pnas.82.5.1518 |
0.331 |
|
| 1984 |
Lindsten T, Finkelman FD, Thompson CB, Andersson B, Scher I. Surface immunoglobulin phenotype of complement receptor-positive and complement receptor-negative B cells of normal and xid immunodeficient mice. European Journal of Immunology. 14: 329-335. PMID 6609823 DOI: 10.1002/Eji.1830140410 |
0.354 |
|
| 1984 |
Thompson CB, June CH, Sullivan KM, Thomas ED. Association between cyclosporin neurotoxicity and hypomagnesaemia. Lancet. 2: 1116-20. PMID 6150182 DOI: 10.1016/S0140-6736(84)91556-3 |
0.314 |
|
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