Greg Elgar - Publications

Development and Stem Cells The Francis Crick Institute 

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Dalla Rosa I, Cámara Y, Durigon R, Moss CF, Vidoni S, Akman G, Hunt L, Johnson MA, Grocott S, Wang L, Thorburn DR, Hirano M, Poulton J, Taylor RW, Elgar G, et al. MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria. Plos Genetics. 12: e1005779. PMID 26760297 DOI: 10.1371/Journal.Pgen.1005779  0.92
2015 Hunt LE, Noyvert B, Bhaw-Rosun L, Sesay AK, Paternoster L, Nohr EA, Davey Smith G, Tommerup N, Sørensen TI, Elgar G. Complete re-sequencing of a 2Mb topological domain encompassing the FTO/IRXB genes identifies a novel obesity-associated region upstream of IRX5. Genome Medicine. 7: 126. PMID 26642925 DOI: 10.1186/S13073-015-0250-3  0.92
2015 Pauls S, Goode DK, Petrone L, Oliveri P, Elgar G. Evolution of lineage-specific functions in ancient cis-regulatory modules. Open Biology. 5. PMID 26538567 DOI: 10.1098/Rsob.150079  0.92
2015 Anwar S, Minhas R, Ali S, Lambert N, Kawakami Y, Elgar G, Azam SS, Abbasi AA. Identification and functional characterization of novel transcriptional enhancers involved in regulating human GLI3 expression during early development. Development, Growth & Differentiation. 57: 570-80. PMID 26464005 DOI: 10.1111/Dgd.12239  0.92
2015 Minhas R, Pauls S, Ali S, Doglio L, Khan MR, Elgar G, Abbasi AA. Cis-regulatory control of human GLI2 expression in the developing neural tube and limb bud. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 244: 681-92. PMID 25715918 DOI: 10.1002/Dvdy.24266  0.92
2014 De Silva DR, Nichols R, Elgar G. Purifying selection in deeply conserved human enhancers is more consistent than in coding sequences. Plos One. 9: e103357. PMID 25062004 DOI: 10.1371/Journal.Pone.0103357  0.92
2014 Chen WC, Pauls S, Bacha J, Elgar G, Loose M, Shimeld SM. Dissection of a Ciona regulatory element reveals complexity of cross-species enhancer activity Developmental Biology. 390: 261-272. PMID 24680932 DOI: 10.1016/j.ydbio.2014.03.013  0.92
2014 Parker HJ, Sauka-Spengler T, Bronner M, Elgar G. A reporter assay in lamprey embryos reveals both functional conservation and elaboration of vertebrate enhancers. Plos One. 9: e85492. PMID 24416417 DOI: 10.1371/Journal.Pone.0085492  0.92
2013 Doglio L, Goode DK, Pelleri MC, Pauls S, Frabetti F, Shimeld SM, Vavouri T, Elgar G. Parallel evolution of chordate cis-regulatory code for development. Plos Genetics. 9: e1003904. PMID 24282393 DOI: 10.1371/Journal.Pgen.1003904  0.92
2013 Smith JJ, Kuraku S, Holt C, Sauka-Spengler T, Jiang N, Campbell MS, Yandell MD, Manousaki T, Meyer A, Bloom OE, Morgan JR, Buxbaum JD, Sachidanandam R, Sims C, Garruss AS, ... ... Elgar G, et al. Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution. Nature Genetics. 45: 415-21, 421e1-2. PMID 23435085 DOI: 10.1038/Ng.2568  0.92
2013 Goode DK, Elgar G. Capturing the regulatory interactions of eukaryote genomes. Briefings in Functional Genomics. 12: 142-60. PMID 23117864 DOI: 10.1093/Bfgp/Els041  0.92
2012 Grant J, Mahadevaiah SK, Khil P, Sangrithi MN, Royo H, Duckworth J, McCarrey JR, VandeBerg JL, Renfree MB, Taylor W, Elgar G, Camerini-Otero RD, Gilchrist MJ, Turner JM. Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation. Nature. 487: 254-8. PMID 22722828 DOI: 10.1038/Nature11171  0.92
2012 Pauls S, Smith SF, Elgar G. Lens development depends on a pair of highly conserved Sox21 regulatory elements Developmental Biology. 365: 310-318. PMID 22387845 DOI: 10.1016/j.ydbio.2012.02.025  0.92
2011 Parker HJ, Piccinelli P, Sauka-Spengler T, Bronner M, Elgar G. Ancient Pbx-Hox signatures define hundreds of vertebrate developmental enhancers. Bmc Genomics. 12: 637. PMID 22208168 DOI: 10.1186/1471-2164-12-637  0.92
2011 Johnson LJ, Cotton JA, Lichtenstein CP, Elgar GS, Nichols RA, Polly PD, Le Comber SC. Stops making sense: translational trade-offs and stop codon reassignment. Bmc Evolutionary Biology. 11: 227. PMID 21801361 DOI: 10.1186/1471-2148-11-227  0.92
2011 Kenyon EJ, McEwen GK, Callaway H, Elgar G. Functional analysis of conserved non-coding regions around the short stature hox gene (shox) in whole zebrafish embryos. Plos One. 6: e21498. PMID 21731768 DOI: 10.1371/journal.pone.0021498  0.52
2011 Goode DK, Callaway HA, Cerda GA, Lewis KE, Elgar G. Minor change, major difference: divergent functions of highly conserved cis-regulatory elements subsequent to whole genome duplication events. Development (Cambridge, England). 138: 879-84. PMID 21247963 DOI: 10.1242/Dev.055996  0.92
2009 McEwen GK, Goode DK, Parker HJ, Woolfe A, Callaway H, Elgar G. Early evolution of conserved regulatory sequences associated with development in vertebrates. Plos Genetics. 5: e1000762. PMID 20011110 DOI: 10.1371/Journal.Pgen.1000762  0.92
2009 Goode DK, Elgar G. The PAX258 gene subfamily: a comparative perspective. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 2951-74. PMID 19924770 DOI: 10.1002/Dvdy.22146  0.92
2008 Elgar G, Vavouri T. Tuning in to the signals: noncoding sequence conservation in vertebrate genomes. Trends in Genetics : Tig. 24: 344-52. PMID 18514361 DOI: 10.1016/J.Tig.2008.04.005  0.92
2008 Woolfe A, Elgar G. Organization of conserved elements near key developmental regulators in vertebrate genomes. Advances in Genetics. 61: 307-38. PMID 18282512 DOI: 10.1016/S0065-2660(07)00012-0  0.52
2007 Woolfe A, Goode DK, Cooke J, Callaway H, Smith S, Snell P, McEwen GK, Elgar G. CONDOR: a database resource of developmentally associated conserved non-coding elements. Bmc Developmental Biology. 7: 100. PMID 17760977 DOI: 10.1186/1471-213X-7-100  0.92
2007 Paparidis Z, Abbasi AA, Malik S, Goode DK, Callaway H, Elgar G, deGraaff E, Lopez-Rios J, Zeller R, Grzeschik KH. Ultraconserved non-coding sequence element controls a subset of spatiotemporal GLI3 expression. Development, Growth & Differentiation. 49: 543-53. PMID 17661744 DOI: 10.1111/J.1440-169X.2007.00954.X  0.92
2007 Abnizova I, Walter K, Te Boekhorst R, Elgar G, Gilks WR. Statistical information characterization of conserved non-coding elements in vertebrates. Journal of Bioinformatics and Computational Biology. 5: 533-47. PMID 17636860 DOI: 10.1142/S0219720007002898  0.56
2007 Woolfe A, Elgar G. Comparative genomics using Fugu reveals insights into regulatory subfunctionalization. Genome Biology. 8: R53. PMID 17428329 DOI: 10.1186/gb-2007-8-4-r53  0.52
2007 Abbasi AA, Paparidis Z, Malik S, Goode DK, Callaway H, Elgar G, Grzeschik KH. Human GLI3 intragenic conserved non-coding sequences are tissue-specific enhancers. Plos One. 2: e366. PMID 17426814 DOI: 10.1371/Journal.Pone.0000366  0.92
2007 Vavouri T, Walter K, Gilks WR, Lehner B, Elgar G. Parallel evolution of conserved non-coding elements that target a common set of developmental regulatory genes from worms to humans. Genome Biology. 8: R15. PMID 17274809 DOI: 10.1186/Gb-2007-8-2-R15  0.92
2006 Edwards YJ, Walter K, McEwen G, Vavouri T, Kelly KA, Abnizova I, Woolfe A, Goode DK, Goodson M, North P, Snell P, Callaway H, Smith SF, Gilks WR, Cooke JE, ... Elgar G, et al. Characterisation of conserved non-coding sequences in vertebrate genomes using bioinformatics, statistics and functional studies. Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics. 1: 46-58. PMID 20483234 DOI: 10.1016/J.Cbd.2005.03.001  0.92
2006 McEwen GK, Woolfe A, Goode D, Vavouri T, Callaway H, Elgar G. Ancient duplicated conserved noncoding elements in vertebrates: a genomic and functional analysis. Genome Research. 16: 451-65. PMID 16533910 DOI: 10.1101/Gr.4143406  0.92
2006 Vavouri T, McEwen GK, Woolfe A, Gilks WR, Elgar G. Defining a genomic radius for long-range enhancer action: duplicated conserved non-coding elements hold the key. Trends in Genetics : Tig. 22: 5-10. PMID 16290136 DOI: 10.1016/J.Tig.2005.10.005  0.92
2005 Walter K, Abnizova I, Elgar G, Gilks WR. Striking nucleotide frequency pattern at the borders of highly conserved vertebrate non-coding sequences. Trends in Genetics : Tig. 21: 436-40. PMID 15979195 DOI: 10.1016/J.Tig.2005.06.003  0.56
2005 Vavouri T, Elgar G. Prediction of cis-regulatory elements using binding site matrices--the successes, the failures and the reasons for both. Current Opinion in Genetics & Development. 15: 395-402. PMID 15950456 DOI: 10.1016/J.Gde.2005.05.002  0.92
2005 Goode DK, Snell P, Smith SF, Cooke JE, Elgar G. Highly conserved regulatory elements around the SHH gene may contribute to the maintenance of conserved synteny across human chromosome 7q36.3. Genomics. 86: 172-81. PMID 15939571 DOI: 10.1016/J.Ygeno.2005.04.006  0.92
2005 Fernandes JM, Mackenzie MG, Elgar G, Suzuki Y, Watabe S, Kinghorn JR, Johnston IA. A genomic approach to reveal novel genes associated with myotube formation in the model teleost, Takifugu rubripes. Physiological Genomics. 22: 327-38. PMID 15928209 DOI: 10.1152/Physiolgenomics.00087.2005  0.92
2005 Woolfe A, Goodson M, Goode DK, Snell P, McEwen GK, Vavouri T, Smith SF, North P, Callaway H, Kelly K, Walter K, Abnizova I, Gilks W, Edwards YJ, Cooke JE, ... Elgar G, et al. Highly conserved non-coding sequences are associated with vertebrate development. Plos Biology. 3: e7. PMID 15630479 DOI: 10.1371/Journal.Pbio.0030007  0.92
2004 Cottage A, Mullan L, Portela MB, Hellen E, Carver T, Patel S, Vavouri T, Elgar G, Edwards YJ. Molecular characterisation of the SAND protein family: a study based on comparative genomics, structural bioinformatics and phylogeny. Cellular & Molecular Biology Letters. 9: 739-53. PMID 15647795  0.92
2004 Cardoso JC, Power DM, Elgar G, Clark MS. Duplicated receptors for VIP and PACAP (VPAC1R and PAC1R) in a teleost fish, Fugu rubripes. Journal of Molecular Endocrinology. 33: 411-28. PMID 15525598 DOI: 10.1677/Jme.1.01575  0.92
2003 Clark MS, Edwards YJ, Peterson D, Clifton SW, Thompson AJ, Sasaki M, Suzuki Y, Kikuchi K, Watabe S, Kawakami K, Sugano S, Elgar G, Johnson SL. Fugu ESTs: new resources for transcription analysis and genome annotation. Genome Research. 13: 2747-53. PMID 14613980 DOI: 10.1101/Gr.1691503  0.92
2003 Cardoso JC, Power DM, Elgar G, Clark MS. Isolation and characterisation of the corticotropin releasing factor receptor 1 (CRFR1) gene in a teleost fish, Fugu rubripes. Dna Sequence : the Journal of Dna Sequencing and Mapping. 14: 215-8. PMID 14509835 DOI: 10.1080/1042517031000112624  0.92
2003 Jones AK, Elgar G, Sattelle DB. The nicotinic acetylcholine receptor gene family of the pufferfish, Fugu rubripes. Genomics. 82: 441-51. PMID 13679024 DOI: 10.1016/S0888-7543(03)00153-8  0.92
2003 Sambrook JG, Campbell RD, Elgar G. Characterisation of a gene cluster in Fugu rubripes containing the complement component C4 gene. Gene. 312: 73-83. PMID 12909342 DOI: 10.1016/S0378-1119(03)00602-4  0.92
2003 Lettice LA, Heaney SJ, Purdie LA, Li L, de Beer P, Oostra BA, Goode D, Elgar G, Hill RE, de Graaff E. A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly. Human Molecular Genetics. 12: 1725-35. PMID 12837695 DOI: 10.1093/Hmg/Ddg180  0.92
2003 Cardoso JC, Power DM, Elgar G, Clark MS. Genomic characterisation of putative growth hormone releasing hormone (GHRH) receptor genes in the teleost fish Fugu rubripes. Dna Sequence : the Journal of Dna Sequencing and Mapping. 14: 129-33. PMID 12825354 DOI: 10.1080/1042517031000081142  0.92
2003 Edwards YJ, Carver TJ, Vavouri T, Frith M, Bishop MJ, Elgar G. Theatre: A software tool for detailed comparative analysis and visualization of genomic sequence. Nucleic Acids Research. 31: 3510-7. PMID 12824356 DOI: 10.1093/Nar/Gkg501  0.92
2003 Goode DK, Snell P, Elgar G. Comparative analysis of vertebrate Shh genes identifies novel conserved non-coding sequence. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 192-201. PMID 12647242 DOI: 10.1007/s00335-002-3052-z  0.92
2003 Davidson CJ, Hirt RP, Lal K, Snell P, Elgar G, Tuddenham EG, McVey JH. Molecular evolution of the vertebrate blood coagulation network. Thrombosis and Haemostasis. 89: 420-8. PMID 12624623 DOI: 10.1055/S-0037-1613369  0.92
2002 Sambrook JG, Russell R, Umrania Y, Edwards YJ, Campbell RD, Elgar G, Clark MS. Fugu orthologues of human major histocompatibility complex genes: a genome survey. Immunogenetics. 54: 367-80. PMID 12242588 DOI: 10.1007/S00251-002-0478-0  0.92
2002 Aparicio S, Chapman J, Stupka E, Putnam N, Chia JM, Dehal P, Christoffels A, Rash S, Hoon S, Smit A, Gelpke MD, Roach J, Oh T, Ho IY, Wong M, ... ... Elgar G, et al. Whole-genome shotgun assembly and analysis of the genome of Fugu rubripes. Science (New York, N.Y.). 297: 1301-10. PMID 12142439 DOI: 10.1126/Science.1072104  0.92
2002 Clark MS, Bendell L, Power DM, Warner S, Elgar G, Ingleton PM. Calcitonin: characterisation and expression in a teleost fish, Fugu rubripes. Journal of Molecular Endocrinology. 28: 111-23. PMID 11932208 DOI: 10.1677/Jme.0.0280111  0.92
2002 Dalle Nogare DE, Clark MS, Elgar G, Frame IG, Poulter RT. Xena, a full-length basal retroelement from tetraodontid fish. Molecular Biology and Evolution. 19: 247-55. PMID 11861884 DOI: 10.1093/Oxfordjournals.Molbev.A004078  0.92
2002 Elgar G. Phylogenetic Trees Made Easy Briefings in Functional Genomics and Proteomics. 1: 107-109. DOI: 10.1093/Bfgp/1.1.107  0.32
2001 Bouchireb N, Grützner F, Haaf T, Stephens RJ, Elgar G, Green AJ, Clark MS. Comparative mapping of the human 9q34 region in Fugu rubripes. Cytogenetics and Cell Genetics. 94: 173-9. PMID 11856876 DOI: 10.1159/000048811  0.48
2001 Elgar G. Gene identification using the pufferfish, Fugu rubripes, by sequence scanning. Methods in Molecular Biology (Clifton, N.J.). 175: 249-62. PMID 11462839 DOI: 10.1385/1-59259-235-X:249  0.56
2001 Clarke D, Elgar G, Clark MS. Comparative analysis of human 19p12-13 region in Fugu and mouse. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 12: 478-83. PMID 11353399 DOI: 10.1007/S003350030004  0.92
1999 Elgar G, Clark MS, Meek S, Smith S, Warner S, Edwards YJ, Bouchireb N, Cottage A, Yeo GS, Umrania Y, Williams G, Brenner S. Generation and analysis of 25 Mb of genomic DNA from the pufferfish Fugu rubripes by sequence scanning. Genome Research. 9: 960-71. PMID 10523524 DOI: 10.1101/Gr.9.10.960  0.68
1999 Wentworth JM, Schoenfeld V, Meek S, Elgar G, Brenner S, Chatterjee VK. Isolation and characterisation of the retinoic acid receptor-alpha gene in the Japanese pufferfish, F. rubripes. Gene. 236: 315-23. PMID 10452951 DOI: 10.1016/S0378-1119(99)00265-6  0.32
1999 Clark MS, Edwards YJ, McQueen HA, Meek SE, Smith S, Umrania Y, Warner S, Williams G, Elgar G. Sequence scanning chicken cosmids: a methodology for genome screening. Gene. 227: 223-30. PMID 10023066 DOI: 10.1016/S0378-1119(98)00610-6  0.92
1998 Edwards YJ, Elgar G, Clark MS, Bishop MJ. The identification and characterization of microsatellites in the compact genome of the Japanese pufferfish, Fugu rubripes: perspectives in functional and comparative genomic analyses. Journal of Molecular Biology. 278: 843-54. PMID 9614946 DOI: 10.1006/Jmbi.1998.1752  0.92
1998 Göttgens B, Gilbert JG, Barton LM, Aparicio S, Hawker K, Mistry S, Vaudin M, King A, Bentley D, Elgar G, Green AR. The pufferfish SLP-1 gene, a new member of the SCL/TAL-1 family of transcription factors. Genomics. 48: 52-62. PMID 9503016 DOI: 10.1006/Geno.1997.5162  0.92
1998 Coutelle O, Nyakatura G, Taudien S, Elgar G, Brenner S, Platzer M, Drescher B, Jouet M, Kenwrick S, Rosenthal A. The neural cell adhesion molecule L1: genomic organisation and differential splicing is conserved between man and the pufferfish Fugu. Gene. 208: 7-15. PMID 9479034 DOI: 10.1016/S0378-1119(97)00614-8  0.32
1997 Yeo GS, Elgar G, Sandford R, Brenner S. Cloning and sequencing of complement component C9 and its linkage to DOC-2 in the pufferfish Fugu rubripes. Gene. 200: 203-11. PMID 9373156 DOI: 10.1016/S0378-1119(97)00423-X  0.68
1997 Schofield JP, Elgar G, Greystrong J, Lye G, Deadman R, Micklem G, King A, Brenner S, Vaudin M. Regions of human chromosome 2 (2q32-q35) and mouse chromosome 1 show synteny with the pufferfish genome (Fugu rubripes). Genomics. 45: 158-67. PMID 9339372 DOI: 10.1006/GENO.1997.4913  0.44
1997 Lim EH, Corrochano LM, Elgar G, Brenner S. Genomic structure and sequence analysis of the valyl-tRNA synthetase gene of the Japanese pufferfish, Fugu rubripes. Dna Sequence : the Journal of Dna Sequencing and Mapping. 7: 141-51. PMID 9254008 DOI: 10.3109/10425179709034030  0.44
1997 Elgar G, Clark M, Green A, Sandford R. How good a model is the Fugu genome? Nature. 387: 140. PMID 9144283 DOI: 10.1038/387140B0  0.68
1997 Elgar G. Quality not quantity: the pufferfish genome. Human Molecular Genetics. 1437-42. PMID 8875249 DOI: 10.1093/Hmg/5.Supplement_1.1437  0.4
1996 Elgar G, Sandford R, Aparicio S, Macrae A, Venkatesh B, Brenner S. Small is beautiful: comparative genomics with the pufferfish (Fugu rubripes). Trends in Genetics : Tig. 12: 145-50. PMID 8901419 DOI: 10.1016/0168-9525(96)10018-4  0.68
1996 Andersson L, Archibald A, Ashburner M, Audun S, Barendse W, Bitgood J, Bottema C, Broad T, Brown S, Burt D, Charlier C, Copeland N, Davis S, Davisson M, Edwards J, ... ... Elgar G, et al. Comparative genome organization of vertebrates. The First International Workshop on Comparative Genome Organization. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 7: 717-34. PMID 8854859 DOI: 10.1007/S003359900222  0.92
1996 Venkatesh B, Tay BH, Elgar G, Brenner S. Isolation, characterization and evolution of nine pufferfish (Fugu rubripes) actin genes. Journal of Molecular Biology. 259: 655-65. PMID 8683572 DOI: 10.1006/Jmbi.1996.0347  0.44
1996 Trower MK, Orton SM, Purvis IJ, Sanseau P, Riley J, Christodoulou C, Burt D, See CG, Elgar G, Sherrington R, Rogaev EI, St George-Hyslop P, Brenner S, Dykes CW. Conservation of synteny between the genome of the pufferfish (Fugu rubripes) and the region on human chromosome 14 (14q24.3) associated with familial Alzheimer disease (AD3 locus) Proceedings of the National Academy of Sciences of the United States of America. 93: 1366-9. PMID 8643637 DOI: 10.1073/PNAS.93.4.1366  0.68
1995 Elgar G, Rattray F, Greystrong J, Brenner S. Genomic structure and nucleotide sequence of the p55 gene of the puffer fish Fugu rubripes. Genomics. 27: 442-6. PMID 7558025 DOI: 10.1006/Geno.1995.1075  0.56
1993 Brenner S, Elgar G, Sandford R, Macrae A, Venkatesh B, Aparicio S. Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genome. Nature. 366: 265-8. PMID 8232585 DOI: 10.1038/366265A0  0.68
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