Year |
Citation |
Score |
2024 |
Hu Y, Lopez VA, Xu H, Pfister JP, Song B, Servage KA, Sakurai M, Jones BT, Mendell JT, Wang T, Wu J, Lambowitz AM, Tomchick DR, Pawłowski K, Tagliabracci VS. Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation. Proceedings of the National Academy of Sciences of the United States of America. 121: e2408249121. PMID 39388274 DOI: 10.1073/pnas.2408249121 |
0.376 |
|
2024 |
Yao J, Xu H, Ferrick-Kiddie EA, Nottingham RM, Wu DC, Ares M, Lambowitz AM. Human cells contain myriad excised linear intron RNAs with links to gene regulation and potential utility as biomarkers. Plos Genetics. 20: e1011416. PMID 39325823 DOI: 10.1371/journal.pgen.1011416 |
0.703 |
|
2024 |
Wen X, Xu H, Woolley PR, Conway OM, Yao J, Matouschek A, Lambowitz AM, Paull TT. Senataxin deficiency disrupts proteostasis through nucleolar ncRNA-driven protein aggregation. The Journal of Cell Biology. 223. PMID 38717338 DOI: 10.1083/jcb.202309036 |
0.385 |
|
2024 |
Hu Y, Lopez VA, Xu H, Pfister JP, Song B, Servage KA, Sakurai M, Jones BT, Mendell JT, Wang T, Wu J, Lambowitz AM, Tomchick DR, Pawłowski K, Tagliabracci VS. Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation. Biorxiv : the Preprint Server For Biology. PMID 38712170 DOI: 10.1101/2024.04.24.590974 |
0.395 |
|
2024 |
Mohr G, Yao J, Park SK, Markham L, Lambowitz AM. Mechanisms used for cDNA synthesis and site-specific integration of RNA into DNA genomes by a reverse transcriptase-Cas1 fusion protein. Science Advances. 10: eadk8791. PMID 38608016 DOI: 10.1126/sciadv.adk8791 |
0.459 |
|
2023 |
Mohr G, Yao J, Park SK, Markham LM, Lambowitz AM. Mechanisms used for cDNA synthesis and site-specific integration of RNA into DNA genomes by a reverse transcriptase-Cas1 fusion protein. Biorxiv : the Preprint Server For Biology. PMID 37693417 DOI: 10.1101/2023.09.01.555893 |
0.454 |
|
2023 |
Wylie D, Wang X, Yao J, Xu H, Ferrick-Kiddie EA, Iwase T, Krishnamurthy S, Ueno NT, Lambowitz AM. Inflammatory breast cancer biomarker identification by simultaneous TGIRT-seq profiling of coding and non-coding RNAs in tumors and blood. Medrxiv : the Preprint Server For Health Sciences. PMID 37398275 DOI: 10.1101/2023.05.26.23290469 |
0.339 |
|
2023 |
Cui H, Diedrich JK, Wu DC, Lim JJ, Nottingham RM, Moresco JJ, Yates JR, Blencowe BJ, Lambowitz AM, Schimmel P. Publisher Correction: Arg-tRNA synthetase links inflammatory metabolism to RNA splicing and nuclear trafficking via SRRM2. Nature Cell Biology. PMID 37237245 DOI: 10.1038/s41556-023-01172-2 |
0.652 |
|
2023 |
Cui H, Diedrich JK, Wu DC, Lim JJ, Nottingham RM, Moresco JJ, Yates JR, Blencowe BJ, Lambowitz AM, Schimmel P. Arg-tRNA synthetase links inflammatory metabolism to RNA splicing and nuclear trafficking via SRRM2. Nature Cell Biology. 25: 592-603. PMID 37059883 DOI: 10.1038/s41556-023-01118-8 |
0.632 |
|
2022 |
Park SK, Mohr G, Yao J, Russell R, Lambowitz AM. Group II intron-like reverse transcriptases function in double-strand break repair. Cell. PMID 36113466 DOI: 10.1016/j.cell.2022.08.014 |
0.362 |
|
2022 |
Faucher-Giguère L, Roy A, Deschamps-Francoeur G, Couture S, Nottingham RM, Lambowitz AM, Scott MS, Abou Elela S. High-grade ovarian cancer associated H/ACA snoRNAs promote cancer cell proliferation and survival. Nar Cancer. 4: zcab050. PMID 35047824 DOI: 10.1093/narcan/zcab050 |
0.306 |
|
2021 |
Xu H, Nottingham RM, Lambowitz AM. TGIRT-seq Protocol for the Comprehensive Profiling of Coding and Non-coding RNA Biotypes in Cellular, Extracellular Vesicle, and Plasma RNAs. Bio-Protocol. 11: e4239. PMID 35005084 DOI: 10.21769/BioProtoc.4239 |
0.436 |
|
2021 |
Lentzsch AM, Stamos JL, Yao J, Russell R, Lambowitz AM. Structural basis for template switching by a group II intron-encoded non-LTR-retroelement reverse transcriptase. The Journal of Biological Chemistry. 100971. PMID 34280434 DOI: 10.1016/j.jbc.2021.100971 |
0.461 |
|
2020 |
Yao J, Wu DC, Nottingham RM, Lambowitz AM. Identification of protein-protected mRNA fragments and structured excised intron RNAs in human plasma by TGIRT-seq peak calling. Elife. 9. PMID 32876046 DOI: 10.7554/Elife.60743 |
0.704 |
|
2019 |
Lentzsch AM, Yao J, Russell R, Lambowitz AM. Template switching mechanism of a group II intron-encoded reverse transcriptase and its implications for biological function and RNA-Seq. The Journal of Biological Chemistry. PMID 31712313 DOI: 10.1074/Jbc.Ra119.011337 |
0.545 |
|
2019 |
Reinsborough CW, Ipas H, Abell NS, Nottingham RM, Yao J, Devanathan SK, Shelton SB, Lambowitz AM, Xhemalçe B. BCDIN3D regulates tRNAHis 3' fragment processing. Plos Genetics. 15: e1008273. PMID 31329584 DOI: 10.1371/Journal.Pgen.1008273 |
0.393 |
|
2019 |
Xu H, Yao J, Wu DC, Lambowitz AM. Improved TGIRT-seq methods for comprehensive transcriptome profiling with decreased adapter dimer formation and bias correction. Scientific Reports. 9: 7953. PMID 31138886 DOI: 10.1038/S41598-019-44457-Z |
0.718 |
|
2019 |
Belfort M, Lambowitz AM. Group II Intron RNPs and Reverse Transcriptases: From Retroelements to Research Tools. Cold Spring Harbor Perspectives in Biology. 11. PMID 30936187 DOI: 10.1101/Cshperspect.A032375 |
0.546 |
|
2018 |
Mohr G, Silas S, Stamos JL, Makarova KS, Markham LM, Yao J, Lucas-Elío P, Sanchez-Amat A, Fire AZ, Koonin EV, Lambowitz AM. A Reverse Transcriptase-Cas1 Fusion Protein Contains a Cas6 Domain Required for Both CRISPR RNA Biogenesis and RNA Spacer Acquisition. Molecular Cell. PMID 30344094 DOI: 10.1016/J.Molcel.2018.09.013 |
0.512 |
|
2018 |
Wu DC, Yao J, Ho KS, Lambowitz AM, Wilke CO. Limitations of alignment-free tools in total RNA-seq quantification. Bmc Genomics. 19: 510. PMID 29969991 DOI: 10.1186/S12864-018-4869-5 |
0.694 |
|
2018 |
Mohr G, Kang SY, Park SK, Qin Y, Grohman J, Yao J, Stamos JL, Lambowitz AM. A highly proliferative group IIC intron from Geobacillus stearothermophilus reveals new features of group II intron mobility and splicing. Journal of Molecular Biology. PMID 29913158 DOI: 10.1016/J.Jmb.2018.06.019 |
0.584 |
|
2018 |
Boivin V, Deschamps-Francoeur G, Couture S, Nottingham R, Bouchard-Bourelle P, Lambowitz AM, Scott MS, Abou Elela S. Simultaneous sequencing of coding and non-coding RNA reveals a human transcriptome dominated by a small number of highly expressed non-coding genes. Rna (New York, N.Y.). PMID 29703781 DOI: 10.1261/Rna.064493.117 |
0.505 |
|
2018 |
Wu DC, Lambowitz AM. Author Correction: Facile single-stranded DNA sequencing of human plasma DNA via thermostable group II intron reverse transcriptase template switching. Scientific Reports. 8: 4056. PMID 29497064 DOI: 10.1038/S41598-018-21665-7 |
0.664 |
|
2017 |
Stamos JL, Lentzsch AM, Lambowitz AM. Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications. Molecular Cell. PMID 29153391 DOI: 10.1016/J.Molcel.2017.10.024 |
0.568 |
|
2017 |
Shurtleff MJ, Yao J, Qin Y, Nottingham RM, Temoche-Diaz MM, Schekman R, Lambowitz AM. Broad role for YBX1 in defining the small noncoding RNA composition of exosomes. Proceedings of the National Academy of Sciences of the United States of America. 114: E8987-E8995. PMID 29073095 DOI: 10.1073/Pnas.1712108114 |
0.503 |
|
2017 |
Carrell ST, Tang Z, Mohr S, Lambowitz AM, Thornton CA. Detection of expanded RNA repeats using thermostable group II intron reverse transcriptase. Nucleic Acids Research. PMID 29036654 DOI: 10.1093/Nar/Gkx867 |
0.503 |
|
2017 |
Wu DC, Lambowitz AM. Facile single-stranded DNA sequencing of human plasma DNA via thermostable group II intron reverse transcriptase template switching. Scientific Reports. 7: 8421. PMID 28827600 DOI: 10.1038/S41598-017-09064-W |
0.684 |
|
2017 |
Silas S, Makarova KS, Shmakov S, Páez-Espino D, Mohr G, Liu Y, Davison M, Roux S, Krishnamurthy SR, Fu BXH, Hansen LL, Wang D, Sullivan MB, Millard A, Clokie MR, ... ... Lambowitz AM, et al. On the Origin of Reverse Transcriptase-Using CRISPR-Cas Systems and Their Hyperdiverse, Enigmatic Spacer Repertoires. Mbio. 8. PMID 28698278 DOI: 10.1128/Mbio.00897-17 |
0.424 |
|
2016 |
Zubradt M, Gupta P, Persad S, Lambowitz AM, Weissman JS, Rouskin S. DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo. Nature Methods. PMID 27819661 DOI: 10.1038/Nmeth.4057 |
0.483 |
|
2016 |
Burke JM, Kincaid RP, Nottingham RM, Lambowitz AM, Sullivan CS. DUSP11 activity on triphosphorylated transcripts promotes Argonaute association with noncanonical viral microRNAs and regulates steady-state levels of cellular noncoding RNAs. Genes & Development. 30: 2076-2092. PMID 27798849 DOI: 10.1101/Gad.282616.116 |
0.483 |
|
2016 |
Lamech LT, Saoji M, Paukstelis PJ, Lambowitz AM. Structural Divergence of the Group I Intron-Binding Surface in Fungal Mitochondrial Tyrosyl-tRNA Synthetases that Function in RNA Splicing. The Journal of Biological Chemistry. PMID 27036943 DOI: 10.1074/Jbc.M116.725390 |
0.778 |
|
2016 |
Silas S, Mohr G, Sidote DJ, Markham LM, Sanchez-Amat A, Bhaya D, Lambowitz AM, Fire AZ. Direct CRISPR spacer acquisition from RNA by a natural reverse transcriptase-Cas1 fusion protein. Science (New York, N.Y.). 351: aad4234. PMID 26917774 DOI: 10.1126/Science.Aad4234 |
0.566 |
|
2016 |
Nottingham RM, Wu DC, Qin Y, Yao J, Hunicke-Smith S, Lambowitz AM. RNA-seq of human reference RNA samples using a thermostable group II intron reverse transcriptase. Rna (New York, N.Y.). PMID 26826130 DOI: 10.1261/Rna.055558.115 |
0.721 |
|
2016 |
Zubradt M, Gupta P, Persad S, Lambowitz AM, Weissman JS, Rouskin S. Target-specific DMS-MaPseq for in vivo RNA structure determination Protocol Exchange. DOI: 10.1038/Protex.2016.069 |
0.463 |
|
2016 |
Zubradt M, Gupta P, Persad S, Lambowitz AM, Weissman JS, Rouskin S. Genome-wide DMS-MaPseq for in vivo RNA structure determination Protocol Exchange. DOI: 10.1038/Protex.2016.068 |
0.416 |
|
2015 |
Qin Y, Yao J, Wu DC, Nottingham RM, Mohr S, Hunicke-Smith S, Lambowitz AM. High-throughput sequencing of human plasma RNA by using thermostable group II intron reverse transcriptases. Rna (New York, N.Y.). PMID 26554030 DOI: 10.1261/Rna.054809.115 |
0.72 |
|
2015 |
Truong DM, Hewitt FC, Hanson JH, Cui X, Lambowitz AM. Retrohoming of a Mobile Group II Intron in Human Cells Suggests How Eukaryotes Limit Group II Intron Proliferation. Plos Genetics. 11: e1005422. PMID 26241656 DOI: 10.1371/Journal.Pgen.1005422 |
0.681 |
|
2015 |
Zheng G, Qin Y, Clark WC, Dai Q, Yi C, He C, Lambowitz AM, Pan T. Efficient and quantitative high-throughput tRNA sequencing. Nature Methods. PMID 26214130 DOI: 10.1038/Nmeth.3478 |
0.418 |
|
2015 |
Lambowitz AM, Belfort M. Mobile Bacterial Group II Introns at the Crux of Eukaryotic Evolution. Microbiology Spectrum. 3: MDNA3-0050-2014. PMID 26104554 DOI: 10.1128/Microbiolspec.Mdna3-0050-2014 |
0.538 |
|
2015 |
Shen PS, Park J, Qin Y, Li X, Parsawar K, Larson MH, Cox J, Cheng Y, Lambowitz AM, Weissman JS, Brandman O, Frost A. Protein synthesis. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains. Science (New York, N.Y.). 347: 75-8. PMID 25554787 DOI: 10.1126/Science.1259724 |
0.42 |
|
2015 |
Mallam AL, Sidote DJ, Lambowitz AM. Insights into Helicase Evolution from the Specificity and Mechanism of a Dead-Box Protein Biophysical Journal. 108: 335a. DOI: 10.1016/J.Bpj.2014.11.1824 |
0.458 |
|
2014 |
Lamech LT, Mallam AL, Lambowitz AM. Evolution of RNA-protein interactions: non-specific binding led to RNA splicing activity of fungal mitochondrial tyrosyl-tRNA synthetases. Plos Biology. 12: e1002028. PMID 25536042 DOI: 10.1371/Journal.Pbio.1002028 |
0.543 |
|
2014 |
Mallam AL, Sidote DJ, Lambowitz AM. Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase. Elife. 3: e04630. PMID 25497230 DOI: 10.7554/Elife.04630 |
0.491 |
|
2014 |
Katibah GE, Qin Y, Sidote DJ, Yao J, Lambowitz AM, Collins K. Broad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5. Proceedings of the National Academy of Sciences of the United States of America. 111: 12025-30. PMID 25092312 DOI: 10.1073/Pnas.1412842111 |
0.519 |
|
2014 |
Enyeart PJ, Mohr G, Ellington AD, Lambowitz AM. Biotechnological applications of mobile group II introns and their reverse transcriptases: gene targeting, RNA-seq, and non-coding RNA analysis. Mobile Dna. 5: 2. PMID 24410776 DOI: 10.1186/1759-8753-5-2 |
0.611 |
|
2014 |
Mallam AL, Sidote DJ, Lambowitz AM. Author response: Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase Elife. DOI: 10.7554/Elife.04630.021 |
0.496 |
|
2014 |
Lamech LT, Mallam AL, Lambowitz AM. Evolution of RNA-Protein Interactions: Non-Specific Binding Led to RNA Splicing Activity of Fungal Mitochondrial Tyrosyl-tRNA Synthetases Plos Biology. 12. DOI: 10.1371/journal.pbio.1002028 |
0.402 |
|
2014 |
Enyeart PJ, Mohr G, Ellington AD, Lambowitz AM. Biotechnological applications of mobile group II introns and their reverse transcriptases: Gene targeting, RNA-seq, and non-coding RNA analysis Mobile Dna. 5. DOI: 10.1186/1759-8753-5-2 |
0.431 |
|
2013 |
Saldanha RJ, Pemberton A, Shiflett P, Perutka J, Whitt JT, Ellington A, Lambowitz AM, Kramer R, Taylor D, Lamkin TJ. Rapid targeted gene disruption in Bacillus anthracis Bmc Biotechnology. 13. PMID 24047152 DOI: 10.1186/1472-6750-13-72 |
0.31 |
|
2013 |
Truong DM, Sidote DJ, Russell R, Lambowitz AM. Enhanced group II intron retrohoming in magnesium-deficient Escherichia coli via selection of mutations in the ribozyme core. Proceedings of the National Academy of Sciences of the United States of America. 110: E3800-9. PMID 24043808 DOI: 10.1073/Pnas.1315742110 |
0.541 |
|
2013 |
Enyeart PJ, Chirieleison SM, Dao MN, Perutka J, Quandt EM, Yao J, Whitt JT, Keatinge-Clay AT, Lambowitz AM, Ellington AD. Generalized bacterial genome editing using mobile group II introns and Cre-lox. Molecular Systems Biology. 9: 685. PMID 24002656 DOI: 10.1038/Msb.2013.41 |
0.413 |
|
2013 |
Mohr G, Hong W, Zhang J, Cui GZ, Yang Y, Cui Q, Liu YJ, Lambowitz AM. A targetron system for gene targeting in thermophiles and its application in Clostridium thermocellum. Plos One. 8: e69032. PMID 23874856 DOI: 10.1371/Journal.Pone.0069032 |
0.547 |
|
2013 |
Mohr S, Ghanem E, Smith W, Sheeter D, Qin Y, King O, Polioudakis D, Iyer VR, Hunicke-Smith S, Swamy S, Kuersten S, Lambowitz AM. Thermostable group II intron reverse transcriptase fusion proteins and their use in cDNA synthesis and next-generation RNA sequencing. Rna (New York, N.Y.). 19: 958-70. PMID 23697550 DOI: 10.1261/Rna.039743.113 |
0.566 |
|
2013 |
Yao J, Truong DM, Lambowitz AM. Genetic and biochemical assays reveal a key role for replication restart proteins in group II intron retrohoming. Plos Genetics. 9: e1003469. PMID 23637634 DOI: 10.1371/Journal.Pgen.1003469 |
0.546 |
|
2013 |
Russell R, Jarmoskaite I, Lambowitz AM. Toward a molecular understanding of RNA remodeling by DEAD-box proteins. Rna Biology. 10: 44-55. PMID 22995827 DOI: 10.4161/Rna.22210 |
0.518 |
|
2012 |
Mallam AL, Del Campo M, Gilman B, Sidote DJ, Lambowitz AM. Structural basis for RNA-duplex recognition and unwinding by the DEAD-box helicase Mss116p Nature. 490: 121-125. PMID 22940866 DOI: 10.1038/Nature11402 |
0.506 |
|
2012 |
White TB, Lambowitz AM. The retrohoming of linear group II intron RNAs in Drosophila melanogaster occurs by both DNA ligase 4-dependent and -independent mechanisms. Plos Genetics. 8: e1002534. PMID 22359518 DOI: 10.1371/Journal.Pgen.1002534 |
0.586 |
|
2011 |
Mohr G, Del Campo M, Turner KG, Gilman B, Wolf RZ, Lambowitz AM. High-throughput genetic identification of functionally important regions of the yeast DEAD-box protein Mss116p. Journal of Molecular Biology. 413: 952-72. PMID 21945532 DOI: 10.1016/J.Jmb.2011.09.015 |
0.532 |
|
2011 |
Mallam AL, Jarmoskaite I, Tijerina P, Del Campo M, Seifert S, Guo L, Russell R, Lambowitz AM. Solution structures of DEAD-box RNA chaperones reveal conformational changes and nucleic acid tethering by a basic tail Proceedings of the National Academy of Sciences of the United States of America. 108: 12254-12259. PMID 21746911 DOI: 10.1073/Pnas.1109566108 |
0.504 |
|
2011 |
Potratz JP, Del Campo M, Wolf RZ, Lambowitz AM, Russell R. ATP-dependent roles of the DEAD-box protein Mss116p in group II intron splicing in vitro and in vivo Journal of Molecular Biology. 411: 661-679. PMID 21679717 DOI: 10.1016/J.Jmb.2011.05.047 |
0.555 |
|
2011 |
Paukstelis PJ, Chari N, Lambowitz AM, Hoffman D. NMR structure of the C-terminal domain of a Tyrosyl-tRNA synthetase that functions in group i intron splicing Biochemistry. 50: 3816-3826. PMID 21438536 DOI: 10.1021/Bi200189U |
0.749 |
|
2011 |
Lambowitz AM, Zimmerly S. Group II introns: mobile ribozymes that invade DNA. Cold Spring Harbor Perspectives in Biology. 3: a003616. PMID 20463000 DOI: 10.1101/Cshperspect.A003616 |
0.607 |
|
2010 |
Mohr G, Ghanem E, Lambowitz AM. Mechanisms used for genomic proliferation by thermophilic group II introns Plos Biology. 8. PMID 20543989 DOI: 10.1371/Journal.Pbio.1000391 |
0.553 |
|
2010 |
Gu SQ, Cui X, Mou S, Mohr S, Yao J, Lambowitz AM. Genetic identification of potential RNA-binding regions in a group II intron-encoded reverse transcriptase Rna. 16: 732-747. PMID 20179150 DOI: 10.1261/Rna.2007310 |
0.653 |
|
2009 |
Zhuang F, Mastroianni M, White TB, Lambowitz AM. Linear group II intron RNAs can retrohome in eukaryotes and may use nonhomologous end-joining for cDNA ligation Proceedings of the National Academy of Sciences of the United States of America. 106: 18189-18194. PMID 19833873 DOI: 10.1073/Pnas.0910277106 |
0.755 |
|
2009 |
Del Campo M, Lambowitz AM. Structure of the Yeast DEAD Box Protein Mss116p Reveals Two Wedges that Crimp RNA Molecular Cell. 35: 598-609. PMID 19748356 DOI: 10.1016/J.Molcel.2009.07.032 |
0.503 |
|
2009 |
Del Campo M, Lambowitz AM. Crystallization and preliminary X-ray diffraction of the DEAD-box protein Mss116p complexed with an RNA oligonucleotide and AMP-PNP Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 65: 832-835. PMID 19652352 DOI: 10.1107/S1744309109027225 |
0.432 |
|
2009 |
Markov DA, Savkina M, Anikin M, Del Campo M, Ecker K, Lambowitz AM, De Gnore JP, McAllister WT. Identification of proteins associated with the yeast mitochondrial RNA polymerase by tandem affinity purification Yeast. 26: 423-440. PMID 19536766 DOI: 10.1002/Yea.1672 |
0.507 |
|
2009 |
Del Campo M, Mohr S, Jiang Y, Jia H, Jankowsky E, Lambowitz AM. Unwinding by Local Strand Separation Is Critical for the Function of DEAD-Box Proteins as RNA Chaperones Journal of Molecular Biology. 389: 674-693. PMID 19393667 DOI: 10.1016/J.Jmb.2009.04.043 |
0.555 |
|
2009 |
Zhuang F, Karberg M, Perutka J, Lambowitz AM. EcI5, a group IIB intron with high retrohoming frequency: DNA target site recognition and use in gene targeting Rna. 15: 432-449. PMID 19155322 DOI: 10.1261/Rna.1378909 |
0.818 |
|
2008 |
Chen Y, Potratz JP, Tijerina P, Del Campo M, Lambowitz AM, Russell R. DEAD-box proteins can completely separate an RNA duplex using a single ATP Proceedings of the National Academy of Sciences of the United States of America. 105: 20203-20208. PMID 19088196 DOI: 10.1073/Pnas.0811075106 |
0.499 |
|
2008 |
Mastroianni M, Watanabe K, White TB, Zhuang F, Vernon J, Matsuura M, Wallingford J, Lambowitz AM. Group II intron-based gene targeting reactions in eukaryotes. Plos One. 3: e3121. PMID 18769669 DOI: 10.1371/Journal.Pone.0003121 |
0.841 |
|
2008 |
Vicens Q, Paukstelis PJ, Westhof E, Lambowitz AM, Cech TR. Toward predicting self-splicing and protein-facilitated splicing of group I introns. Rna (New York, N.Y.). 14: 2013-29. PMID 18768647 DOI: 10.1261/Rna.1027208 |
0.749 |
|
2008 |
Zhao J, Niu W, Yao J, Mohr S, Marcotte EM, Lambowitz AM. Group II intron protein localization and insertion sites are affected by polyphosphate. Plos Biology. 6: e150. PMID 18593213 DOI: 10.1371/Journal.Pbio.0060150 |
0.637 |
|
2008 |
Dai L, Chai D, Gu SQ, Gabel J, Noskov SY, Blocker FJ, Lambowitz AM, Zimmerly S. A three-dimensional model of a group II intron RNA and its interaction with the intron-encoded reverse transcriptase. Molecular Cell. 30: 472-85. PMID 18424209 DOI: 10.1016/J.Molcel.2008.04.001 |
0.547 |
|
2008 |
Paukstelis PJ, Lambowitz AM. Identification and evolution of fungal mitochondrial tyrosyl-tRNA synthetases with group I intron splicing activity Proceedings of the National Academy of Sciences of the United States of America. 105: 6010-6015. PMID 18413600 DOI: 10.1073/Pnas.0801722105 |
0.778 |
|
2008 |
Paukstelis PJ, Chen JH, Chase E, Lambowitz AM, Golden BL. Structure of a tyrosyl-tRNA synthetase splicing factor bound to a group I intron RNA. Nature. 451: 94-7. PMID 18172503 DOI: 10.1038/Nature06413 |
0.797 |
|
2008 |
Mohr G, Del Campo M, Mohr S, Yang Q, Jia H, Jankowsky E, Lambowitz AM. Function of the C-terminal Domain of the DEAD-box Protein Mss116p Analyzed in Vivo and in Vitro Journal of Molecular Biology. 375: 1344-1364. PMID 18096186 DOI: 10.1016/J.Jmb.2007.11.041 |
0.539 |
|
2007 |
Yang Q, Del Campo M, Lambowitz AM, Jankowsky E. DEAD-Box Proteins Unwind Duplexes by Local Strand Separation Molecular Cell. 28: 253-263. PMID 17964264 DOI: 10.1016/J.Molcel.2007.08.016 |
0.504 |
|
2007 |
Del Campo M, Tijerina P, Bhaskaran H, Mohr S, Yang Q, Jankowsky E, Russell R, Lambowitz AM. Do DEAD-Box Proteins Promote Group II Intron Splicing without Unwinding RNA? Molecular Cell. 28: 159-166. PMID 17936712 DOI: 10.1016/J.Molcel.2007.07.028 |
0.547 |
|
2007 |
Yao J, Lambowitz AM. Gene targeting in gram-negative bacteria by use of a mobile group II intron ("targetron") expressed from a broad-host-range vector Applied and Environmental Microbiology. 73: 2735-2743. PMID 17322321 DOI: 10.1128/Aem.02829-06 |
0.392 |
|
2007 |
Grohman JK, Del Campo M, Bhaskaran H, Tijerina P, Lambowitz AM, Russell R. Probing the mechanisms of DEAD-box proteins as general RNA chaperones: The C-terminal domain of CYT-19 mediates general recognition of RNA Biochemistry. 46: 3013-3022. PMID 17311413 DOI: 10.1021/Bi0619472 |
0.465 |
|
2007 |
Halls C, Mohr S, Del Campo M, Yang Q, Jankowsky E, Lambowitz AM. Involvement of DEAD-box Proteins in Group I and Group II Intron Splicing. Biochemical Characterization of Mss116p, ATP Hydrolysis-dependent and -independent Mechanisms, and General RNA Chaperone Activity Journal of Molecular Biology. 365: 835-855. PMID 17081564 DOI: 10.1016/J.Jmb.2006.09.083 |
0.562 |
|
2006 |
Noah JW, Park S, Whitt JT, Perutka J, Frey W, Lambowitz AM. Atomic force microscopy reveals DNA bending during group II intron ribonucleoprotein particle integration into double-stranded DNA Biochemistry. 45: 12424-12435. PMID 17029398 DOI: 10.1021/Bi060612H |
0.564 |
|
2006 |
Yao J, Zhong J, Fang Y, Geisinger E, Novick RP, Lambowitz AM. Use of targetrons to disrupt essential and nonessential genes in Staphylococcus aureus reveals temperature sensitivity of Ll.LtrB group II intron splicing. Rna (New York, N.Y.). 12: 1271-81. PMID 16741231 DOI: 10.1261/Rna.68706 |
0.602 |
|
2006 |
Mohr S, Matsuura M, Perlman PS, Lambowitz AM. A DEAD-box protein alone promotes group II intron splicing and reverse splicing by acting as an RNA chaperone Proceedings of the National Academy of Sciences of the United States of America. 103: 3569-3574. PMID 16505350 DOI: 10.1073/Pnas.0600332103 |
0.543 |
|
2006 |
Pyle AM, Lambowitz AM. 17 Group II Introns: Ribozymes That Splice RNA and Invade DNA Cold Spring Harbor Monograph Archive. 43: 469-505. DOI: 10.1101/087969739.43.469 |
0.525 |
|
2005 |
Smith D, Zhong J, Matsuura M, Lambowitz AM, Belfort M. Recruitment of host functions suggests a repair pathway for late steps in group II intron retrohoming Genes and Development. 19: 2477-2487. PMID 16230535 DOI: 10.1101/Gad.1345105 |
0.653 |
|
2005 |
Zhao J, Lambowitz AM. A bacterial group II intron-encoded reverse transcriptase localizes to cellular poles Proceedings of the National Academy of Sciences of the United States of America. 102: 16133-16140. PMID 16186487 DOI: 10.1073/Pnas.0507057102 |
0.633 |
|
2005 |
Yao J, Zhong J, Lambowitz AM. Gene targeting using randomly inserted group II introns (targetrons) recovered from an Escherichia coli gene disruption library Nucleic Acids Research. 33: 3351-3362. PMID 15947133 DOI: 10.1093/Nar/Gki649 |
0.715 |
|
2005 |
Jones JP, Kierlin MN, Coon RG, Perutka J, Lambowitz AM, Sullenger BA. Retargeting mobile group II introns to repair mutant genes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 687-94. PMID 15851007 DOI: 10.1016/J.Ymthe.2005.01.014 |
0.393 |
|
2005 |
Coros CJ, Landthaler M, Piazza CL, Beauregard A, Esposito D, Perutka J, Lambowitz AM, Belfort M. Retrotransposition strategies of the Lactococcus lactis Ll.LtrB group II intron are dictated by host identity and cellular environment Molecular Microbiology. 56: 509-524. PMID 15813740 DOI: 10.1111/J.1365-2958.2005.04554.X |
0.487 |
|
2005 |
Paukstelis PJ, Coon R, Madabusi L, Nowakowski J, Monzingo A, Robertus J, Lambowitz AM. A tyrosyl-tRNA synthetase adapted to function in group I intron splicing by acquiring a new RNA binding surface Molecular Cell. 17: 417-428. PMID 15694342 DOI: 10.1016/J.Molcel.2004.12.026 |
0.768 |
|
2005 |
Huang HR, Rowe CE, Mohr S, Jiang Y, Lambowitz AM, Perlman PS. The splicing of yeast mitochondrial group I and group II introns requires a DEAD-box protein with RNA chaperone function Proceedings of the National Academy of Sciences of the United States of America. 102: 163-168. PMID 15618406 DOI: 10.1073/Pnas.0407896101 |
0.568 |
|
2005 |
Blocker FJH, Mohr G, Conlan LH, Qi L, Belfort M, Lambowitz AM. Domain structure and three-dimensional model of a group II intron-encoded reverse transcriptase Rna. 11: 14-28. PMID 15574519 DOI: 10.1261/Rna.7181105 |
0.513 |
|
2004 |
Lambowitz AM, Zimmerly S. Mobile group II introns Annual Review of Genetics. 38: 1-35. PMID 15568970 DOI: 10.1146/Annurev.Genet.38.072902.091600 |
0.57 |
|
2004 |
Watanabe K, Lambowitz AM. High-affinity binding site for a group II intron-encoded reverse transcriptase/maturase within a stem-loop structure in the intron RNA Rna. 10: 1433-1443. PMID 15273321 DOI: 10.1261/Rna.7730104 |
0.502 |
|
2004 |
Cui X, Matsuura M, Wang Q, Ma H, Lambowitz AM. A group II intron-encoded maturase functions preferentially In Cis and requires both the reverse transcriptase and X domains to promote RNA splicing Journal of Molecular Biology. 340: 211-231. PMID 15201048 DOI: 10.1016/J.Jmb.2004.05.004 |
0.671 |
|
2004 |
Chen X, Mohr G, Lambowitz AM. The Neurosporea crassa CYT-18 protein C-terminal RNA-binding domain helps stabilize interdomain tertiary interactions in group I introns Rna. 10: 634-644. PMID 15037773 DOI: 10.1261/Rna.5212604 |
0.522 |
|
2004 |
Perutka J, Wang W, Goerlitz D, Lambowitz AM. Use of Computer-designed Group II Introns to Disrupt Escherichia coli DExH/D-box Protein and DNA Helicase Genes Journal of Molecular Biology. 336: 421-439. PMID 14757055 DOI: 10.1016/J.Jmb.2003.12.009 |
0.563 |
|
2003 |
Huang HR, Chao MY, Armstrong B, Wang Y, Lambowitz AM, Perlman PS. The DIVa Maturase Binding Site in the Yeast Group II Intron aI2 Is Essential for Intron Homing but Not for In Vivo Splicing Molecular and Cellular Biology. 23: 8809-8819. PMID 14612420 DOI: 10.1128/Mcb.23.23.8809-8819.2003 |
0.543 |
|
2003 |
Noah JW, Lambowitz AM. Effects of Maturase Binding and Mg2+ Concentration on Group II Intron RNA Folding Investigated by UV Cross-Linking Biochemistry. 42: 12466-12480. PMID 14580192 DOI: 10.1021/Bi035339N |
0.481 |
|
2003 |
Zhong J, Lambowitz AM. Group II intron mobility using nascent strands at DNA replication forks to prime reverse transcription Embo Journal. 22: 4555-4565. PMID 12941706 DOI: 10.1093/Emboj/Cdg433 |
0.687 |
|
2003 |
Aizawa Y, Xiang Q, Lambowitz AM, Pyle AM. The pathway for DNA recognition and RNA integration by a group II intron retrotransposon. Molecular Cell. 11: 795-805. PMID 12667460 DOI: 10.1016/S1097-2765(03)00069-8 |
0.527 |
|
2003 |
Muñoz-Adelantado E, San Filippo J, Martínez-Abarca F, García-Rodríguez FM, Lambowitz AM, Toro N. Mobility of the Sinorhizobium meliloti group II intron RmInt1 occurs by reverse splicing into DNA, but requires an unknown reverse transcriptase priming mechanism Journal of Molecular Biology. 327: 931-943. PMID 12662921 DOI: 10.1016/S0022-2836(03)00208-0 |
0.575 |
|
2003 |
Zhong J, Karberg M, Lambowitz AM. Targeted and random bacterial gene disruption using a group II intron (targetron) vector containing a retrotransposition-activated selectable marker Nucleic Acids Research. 31: 1656-1664. PMID 12626707 DOI: 10.1093/Nar/Gkg248 |
0.803 |
|
2003 |
Frazier CL, San Filippo J, Lambowitz AM, Mills DA. Genetic manipulation of Lactococcus lactis by using targeted group II introns: generation of stable insertions without selection. Applied and Environmental Microbiology. 69: 1121-8. PMID 12571038 DOI: 10.1128/Aem.69.2.1121-1128.2003 |
0.467 |
|
2003 |
Mohr G, Lambowitz AM. Putative proteins related to group II intron reverse transcriptase/maturases are encoded by nuclear genes in higher plants Nucleic Acids Research. 31: 647-652. PMID 12527773 DOI: 10.1093/Nar/Gkg153 |
0.528 |
|
2002 |
San Filippo J, Lambowitz AM. Characterization of the C-Terminal DNA-binding/DNA endonuclease region of a group II intron-encoded protein Journal of Molecular Biology. 324: 933-951. PMID 12470950 DOI: 10.1016/S0022-2836(02)01147-6 |
0.499 |
|
2002 |
Mohr S, Stryker JM, Lambowitz AM. A DEAD-Box protein functions as an ATP-dependent RNA chaperone in group I intron splicing Cell. 109: 769-779. PMID 12086675 DOI: 10.1016/S0092-8674(02)00771-7 |
0.533 |
|
2002 |
Singh RN, Saldanha RJ, D'Souza LM, Lambowitz AM. Binding of a group II intron-encoded reverse transcriptase/maturase to its high affinity intron RNA binding site involves sequence-specific recognition and autoregulates translation Journal of Molecular Biology. 318: 287-303. PMID 12051838 DOI: 10.1016/S0022-2836(02)00054-2 |
0.496 |
|
2002 |
Myers CA, Kuhla B, Cusack S, Lambowitz AM. tRNA-like recognition of group I introns by a tyrosyl-tRNA synthetase Proceedings of the National Academy of Sciences of the United States of America. 99: 2630-2635. PMID 11854463 DOI: 10.1073/Pnas.052596299 |
0.506 |
|
2002 |
Matsuura M, Noah JW, Lambowitz AM. Mechanism of maturase-promoted group II intron splicing Embo Journal. 20: 7259-7270. PMID 11743002 DOI: 10.1093/Emboj/20.24.7259 |
0.504 |
|
2001 |
Karberg M, Guo H, Zhong J, Coon R, Perutka J, Lambowitz AM. Group II introns as controllable gene targeting vectors for genetic manipulation of bacteria Nature Biotechnology. 19: 1162-1167. PMID 11731786 DOI: 10.1038/Nbt1201-1162 |
0.787 |
|
2001 |
Dickson L, Huang HR, Liu L, Matsuura M, Lambowitz AM, Perlman PS. Retrotransposition of a yeast group II intron occurs by reverse splicing directly into ectopic DNA sites Proceedings of the National Academy of Sciences of the United States of America. 98: 13207-13212. PMID 11687644 DOI: 10.1073/Pnas.231494498 |
0.548 |
|
2001 |
Singh NN, Lambowitz AM. Interaction of a group II intron ribonucleoprotein endonuclease with its DNA target site investigated by DNA footprinting and modification interference Journal of Molecular Biology. 309: 361-386. PMID 11371159 DOI: 10.1006/Jmbi.2001.4658 |
0.574 |
|
2001 |
Caprara MG, Myers CA, Lambowitz AM. Interaction of the Neurospora crassa mitochondrial tyrosyl-tRNA synthetase (CYT-18 protein) with the group I intron P4-P6 domain. Thermodynamic analysis and the role of metal ions Journal of Molecular Biology. 308: 165-190. PMID 11327760 DOI: 10.1006/Jmbi.2001.4581 |
0.39 |
|
2001 |
Mohr G, Rennard R, Cherniack AD, Stryker J, Lambowitz AM. Function of the Neurospora crassa mitochondrial tyrosyl-tRNA synthetase in RNA splicing. Role of the idiosyncratic N-terminal extension and different modes of interaction with different group I introns Journal of Molecular Biology. 307: 75-92. PMID 11243805 DOI: 10.1006/Jmbi.2000.4460 |
0.656 |
|
2000 |
Eskes R, Liu L, Ma H, Chao MY, Dickson L, Lambowitz AM, Perlman PS. Multiple homing pathways used by yeast mitochondrial group II introns Molecular and Cellular Biology. 20: 8432-8446. PMID 11046140 DOI: 10.1128/Mcb.20.22.8432-8446.2000 |
0.571 |
|
2000 |
Mohr S, Wanner LA, Bertrand H, Lambowitz AM. Characterization of an unusual tRNA-like sequence found inserted in a Neurospora retroplasmid. Nucleic Acids Research. 28: 1514-24. PMID 11001704 DOI: 10.1093/Nar/28.7.1514 |
0.437 |
|
2000 |
Chen X, Gutell RR, Lambowitz AM. Function of tyrosyl-tRNA synthetase in splicing group I introns: An induced-fit model for binding to the P4-P6 domain based on analysis of mutations at the junction of the P4-P6 stacked helices Journal of Molecular Biology. 301: 265-283. PMID 10926509 DOI: 10.1006/Jmbi.2000.3963 |
0.348 |
|
2000 |
Guo H, Karberg M, Long M, Jones JP, Sullenger B, Lambowitz AM. Group II introns designed to insert into therapeutically relevant DNA target sites in human cells. Science (New York, N.Y.). 289: 452-7. PMID 10903206 DOI: 10.1126/Science.289.5478.452 |
0.817 |
|
2000 |
Mohr G, Smith D, Belfort M, Lambowitz AM. Rules for DNA target-site recognition by a lactococcal group II intron enable retargeting of the intron to specific DNA sequences Genes and Development. 14: 559-573. PMID 10716944 DOI: 10.1101/Gad.14.5.559 |
0.598 |
|
2000 |
Mohr S, Wanner LA, Bertrand H, Lambowitz AM. Characterization of an unusual tRNA-like sequence found inserted in a Neurospora retroplasmid. Nucleic Acids Research. 28: 1514-24. PMID 10710417 |
0.331 |
|
1999 |
Wank H, SanFilippo J, Singh RN, Matsuura M, Lambowitz AM. A reverse transcriptase/maturase promotes splicing by binding at its own coding segment in a group II intron RNA Molecular Cell. 4: 239-250. PMID 10488339 DOI: 10.1016/S1097-2765(00)80371-8 |
0.735 |
|
1999 |
Saldanha R, Chen B, Wank H, Matsuura M, Edwards J, Lambowitz AM. RNA and protein catalysis in group II intron splicing and mobility reactions using purified components Biochemistry. 38: 9069-9083. PMID 10413481 DOI: 10.1021/Bi982799L |
0.597 |
|
1999 |
Zimmerly S, Moran JV, Perlman PS, Lambowitz AM. Group II intron reverse transcriptase in yeast mitochondria. Stabilization and regulation of reverse transcriptase activity by the intron RNA Journal of Molecular Biology. 289: 473-490. PMID 10356323 DOI: 10.1006/Jmbi.1999.2778 |
0.575 |
|
1999 |
Lambowitz AM, Caprara MG, Zimmerly S, Perlman PS. 18 Group I and Group II Ribozymes as RNPs: Clues to the Past and Guides to the Future Cold Spring Harbor Monograph Archive. 37: 451-485. DOI: 10.1101/087969589.37.451 |
0.574 |
|
1998 |
Yang J, Mohr G, Perlman PS, Lambowitz AM. Group II intron mobility in yeast mitochondria: Target DNA-primed reverse transcription activity of all and reverse splicing into DNA transposition sites in vitro Journal of Molecular Biology. 282: 505-523. PMID 9737919 DOI: 10.1006/Jmbi.1998.2029 |
0.598 |
|
1998 |
Cousineau B, Smith D, Lawrence-Cavanagh S, Mueller JE, Yang J, Mills D, Manias D, Dunny G, Lambowitz AM, Belfort M. Retrohoming of a bacterial group II intron: Mobility via complete reverse splicing, independent of homologous DNA recombination Cell. 94: 451-462. PMID 9727488 DOI: 10.1016/S0092-8674(00)81586-X |
0.525 |
|
1997 |
Guo H, Zimmerly S, Perlman PS, Lambowitz AM. Group II intron endonucleases use both RNA and protein subunits for recognition of specific sequences in double-stranded DNA Embo Journal. 16: 6835-6848. PMID 9362497 DOI: 10.1093/Emboj/16.22.6835 |
0.696 |
|
1997 |
Matsuura M, Saldanha R, Ma H, Wank H, Yang J, Mohr G, Cavanagh S, Dunny GM, Belfort M, Lambowitz AM. A bacterial group II intron encoding reverse transcriptase, maturase, and DNA endonuclease activities: Biochemical demonstration of maturase activity and insertion of new genetic information within the intron Genes and Development. 11: 2910-2924. PMID 9353259 DOI: 10.1101/Gad.11.21.2910 |
0.61 |
|
1997 |
Chen B, Lambowitz AM. De novo and DNA primer-mediated initiation of cDNA synthesis by the mauriceville retroplasmid reverse transcriptase involve recognition of a 3' CCA sequence Journal of Molecular Biology. 271: 311-332. PMID 9268661 DOI: 10.1006/Jmbi.1997.1185 |
0.508 |
|
1997 |
Chiang CC, Lambowitz AM. The Mauriceville retroplasmid reverse transcriptase initiates cDNA synthesis de novo at the 3' end of tRNAs Molecular and Cellular Biology. 17: 4526-4535. PMID 9234710 DOI: 10.1128/Mcb.17.8.4526 |
0.482 |
|
1997 |
Eskes R, Yang J, Lambowitz AM, Perlman PS. Mobility of yeast mitochondrial group II introns: Engineering a new site specificity and retrohoming via full reverse splicing Cell. 88: 865-874. PMID 9118229 DOI: 10.1016/S0092-8674(00)81932-7 |
0.575 |
|
1997 |
Wallweber GJ, Mohr S, Rennard R, Caprara MG, Lambowitz AM. Characterization of Neurospora mitochondrial group I introns reveals different CYT-18 dependent and independent splicing strategies and an alternative 3' splice site for an intron ORF Rna. 3: 114-131. PMID 9042940 |
0.429 |
|
1996 |
Caprara MG, Lehnert V, Lambowitz AM, Westhof E. A tyrosyl-tRNA synthetase recognizes a conserved tRNA-like structural motif in the group I intron catalytic core Cell. 87: 1135-1145. PMID 8978617 DOI: 10.1016/S0092-8674(00)81807-3 |
0.544 |
|
1996 |
Myers CA, Wallweber GJ, Rennard R, Kemel Y, Caprara MG, Mohr G, Lambowitz AM. A tyrosyl-tRNA synthetase suppresses structural defects in the two major helical domains of the group I intron catalytic core Journal of Molecular Biology. 262: 87-104. PMID 8831782 DOI: 10.1006/Jmbi.1996.0501 |
0.317 |
|
1996 |
Saldanha R, Ellington A, Lambowitz AM. Analysis of the CYT-18 protein binding site at the junction of stacked helices in a group I intron RNA by quantitative binding assays and in vitro selection Journal of Molecular Biology. 261: 23-42. PMID 8760500 DOI: 10.1006/Jmbi.1996.0439 |
0.385 |
|
1996 |
Yang J, Zimmerly S, Perlman PS, Lambowitz AM. Efficient integration of an intron RNA into double-stranded DNA by reverse splicing Nature. 381: 332-335. PMID 8692273 DOI: 10.1038/381332A0 |
0.591 |
|
1996 |
Caprara MG, Mohr G, Lambowitz AM. A tyrosyl-tRNA synthetase protein induces tertiary folding of the group I intron catalytic core Journal of Molecular Biology. 257: 512-531. PMID 8648621 DOI: 10.1006/Jmbi.1996.0182 |
0.423 |
|
1995 |
Zimmerly S, Guo H, Perlman PS, Lambowitz AM. Group II intron mobility occurs by target DNA-primed reverse transcription. Cell. 82: 545-54. PMID 7664334 DOI: 10.1016/0092-8674(95)90027-6 |
0.697 |
|
1995 |
Zimmerly S, Guo H, Eskes R, Yang J, Perlman PS, Lambowitz AM. A group II intron RNA is a catalytic component of a DNA endonuclease involved in intron mobility. Cell. 83: 529-38. PMID 7585955 DOI: 10.1016/0092-8674(95)90092-6 |
0.675 |
|
1995 |
Moran JV, Zimmerly S, Eskes R, Kennell JC, Lambowitz AM, Butow RA, Perlman PS. Mobile group II introns of yeast mitochondrial DNA are novel site-specific retroelements. Molecular and Cellular Biology. 15: 2828-38. PMID 7537853 DOI: 10.1128/Mcb.15.5.2828 |
0.54 |
|
1995 |
Kennell JC, Saville BJ, Mohr S, Kuiper MT, Sabourin JR, Collins RA, Lambowitz AM. The VS catalytic RNA replicates by reverse transcription as a satellite of a retroplasmid. Genes & Development. 9: 294-303. PMID 7532606 DOI: 10.1101/Gad.9.3.294 |
0.53 |
|
1995 |
Lambowitz AM. Involvement of neurospora mitochondrial tyrosyl-tRNA synthetase in RNA splicing. A new method for purifying the protein and characterization of physical and enzymatic properties pertinent to splicing Biochemistry®. 34: 1275-1287. PMID 7530051 DOI: 10.1021/Bi00004A022 |
0.526 |
|
1995 |
Lambowitz AM, Chiang C. The Mauriceville and Varkud plasmids: primitive retroelements found in Neurospora mitochondria Canadian Journal of Botany. 73: 173-179. DOI: 10.1139/B95-242 |
0.528 |
|
1994 |
Kennell JC, Wang H, Lambowitz AM. The Mauriceville plasmid of Neurospora spp. uses novel mechanisms for initiating reverse transcription in vivo. Molecular and Cellular Biology. 14: 3094-107. PMID 8164665 DOI: 10.1128/Mcb.14.5.3094 |
0.514 |
|
1994 |
Mohr G, Caprara MG, Guo Q, Lambowitz AM. A tyrosyl-tRNA synthetase can function similarly to an RNA structure in the Tetrahymena ribozyme. Nature. 370: 147-50. PMID 8022484 DOI: 10.1038/370147A0 |
0.52 |
|
1994 |
Chiang CC, Kennell JC, Wanner LA, Lambowitz AM. A mitochondrial retroplasmid integrates into mitochondrial DNA by a novel mechanism involving the synthesis of a hybrid cDNA and homologous recombination. Molecular and Cellular Biology. 14: 6419-32. PMID 7523850 DOI: 10.1128/Mcb.14.10.6419 |
0.45 |
|
1993 |
Saldanha R, Mohr G, Belfort M, Lambowitz AM. Group I and group II introns. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 7: 15-24. PMID 8422962 DOI: 10.1096/Fasebj.7.1.8422962 |
0.526 |
|
1993 |
Mohr G, Perlman PS, Lambowitz AM. Evolutionary relationships among group II intron-encoded proteins and identification of a conserved domain that may be related to maturase function. Nucleic Acids Research. 21: 4991-7. PMID 8255751 DOI: 10.1093/Nar/21.22.4991 |
0.462 |
|
1993 |
Wang H, Lambowitz AM. Reverse transcription of the Mauriceville plasmid of Neurospora. Lack of ribonuclease H activity associated with the reverse transcriptase and possible use of mitochondrial ribonuclease H. The Journal of Biological Chemistry. 268: 18951-9. PMID 7689563 |
0.321 |
|
1993 |
Kennell JC, Moran JV, Perlman PS, Butow RA, Lambowitz AM. Reverse transcriptase activity associated with maturase-encoding group II introns in yeast mitochondria. Cell. 73: 133-46. PMID 7681727 DOI: 10.1016/0092-8674(93)90166-N |
0.456 |
|
1993 |
Wang H, Lambowitz AM. The Mauriceville plasmid reverse transcriptase can initiate cDNA synthesis de novo and may be related to reverse transcriptase and DNA polymerase progenitor. Cell. 75: 1071-81. PMID 7505202 DOI: 10.1016/0092-8674(93)90317-J |
0.537 |
|
1992 |
Mohr G, Zhang A, Gianelos JA, Belfort M, Lambowitz AM. The neurospora CYT-18 protein suppresses defects in the phage T4 td intron by stabilizing the catalytically active structure of the intron core. Cell. 69: 483-94. PMID 1533818 DOI: 10.1016/0092-8674(92)90449-M |
0.455 |
|
1992 |
Kämper U, Kück U, Cherniack AD, Lambowitz AM. The mitochondrial tyrosyl-tRNA synthetase of Podospora anserina is a bifunctional enzyme active in protein synthesis and RNA splicing Molecular and Cellular Biology. 12: 499-511. PMID 1531084 DOI: 10.1128/Mcb.12.2.499 |
0.666 |
|
1992 |
Wang H, Kennell JC, Kuiper MT, Sabourin JR, Saldanha R, Lambowitz AM. The Mauriceville plasmid of Neurospora crassa: characterization of a novel reverse transcriptase that begins cDNA synthesis at the 3' end of template RNA. Molecular and Cellular Biology. 12: 5131-44. PMID 1383691 DOI: 10.1128/Mcb.12.11.5131 |
0.509 |
|
1992 |
Guo Q, Lambowitz AM. A tyrosyl-tRNA synthetase binds specifically to the group I intron catalytic core. Genes & Development. 6: 1357-72. PMID 1379562 DOI: 10.1101/Gad.6.8.1357 |
0.501 |
|
1992 |
Nargang FE, Pande S, Kennell JC, Akins RA, Lambowitz AM. Evidence that a 1.6 kilobase region of Neurospora mtDNA was derived by insertion of part of the LaBelle mitochondrial plasmid. Nucleic Acids Research. 20: 1101-8. PMID 1312706 DOI: 10.1093/Nar/20.5.1101 |
0.424 |
|
1992 |
Turcq B, Dobinson KF, Serizawa N, Lambowitz AM. A protein required for RNA processing and splicing in Neurospora mitochondria is related to gene products involved in cell cycle protein phosphatase functions. Proceedings of the National Academy of Sciences of the United States of America. 89: 1676-80. PMID 1311848 DOI: 10.1073/Pnas.89.5.1676 |
0.449 |
|
1991 |
Lambowitz AM, Perlman PS. Involvement of aminoacyl-tRNA synthetases and other proteins in group I and group II intron splicing. Trends in Biochemical Sciences. 15: 440-4. PMID 2278103 DOI: 10.1016/0968-0004(90)90283-H |
0.445 |
|
1991 |
Kubelik AR, Turcq B, Lambowitz AM. The Neurospora crassa cyt-20 gene encodes cytosolic and mitochondrial valyl-tRNA synthetases and may have a second function in addition to protein synthesis. Molecular and Cellular Biology. 11: 4022-35. PMID 1830127 DOI: 10.1128/Mcb.11.8.4022 |
0.344 |
|
1991 |
Kittle JD, Mohr G, Gianelos JA, Wang H, Lambowitz AM. The Neurospora mitochondrial tyrosyl-tRNA synthetase is sufficient for group I intron splicing in vitro and uses the carboxy-terminal tRNA-binding domain along with other regions. Genes & Development. 5: 1009-21. PMID 1828448 DOI: 10.1101/Gad.5.6.1009 |
0.483 |
|
1991 |
Schulte U, Lambowitz AM. The LaBelle mitochondrial plasmid of Neurospora intermedia encodes a novel DNA polymerase that may be derived from a reverse transcriptase. Molecular and Cellular Biology. 11: 1696-706. PMID 1705012 DOI: 10.1128/Mcb.11.3.1696 |
0.478 |
|
1991 |
Mohr G, Lambowitz AM. Integration of a group I intron into a ribosomal RNA sequence promoted by a tyrosyl-tRNA synthetase. Nature. 354: 164-7. PMID 1658660 DOI: 10.1038/354164A0 |
0.565 |
|
1990 |
Akins RA, Lambowitz AM. Analysis of large deletions in the Mauriceville and Varkud mitochondrial plasmids of Neurospora Current Genetics. 18: 365-369. PMID 2253274 DOI: 10.1007/Bf00318218 |
0.419 |
|
1990 |
Cherniack AD, Garriga G, Kittle JD, Akins RA, Lambowitz AM. Function of Neurospora mitochondrial tyrosyl-tRNA synthetase in RNA splicing requires an idiosyncratic domain not found in other synthetases. Cell. 62: 745-55. PMID 2143700 DOI: 10.1016/0092-8674(90)90119-Y |
0.686 |
|
1989 |
Kennell JC, Lambowitz AM. Development of an in vitro transcription system for Neurospora crassa mitochondrial DNA and identification of transcription initiation sites. Molecular and Cellular Biology. 9: 3603-13. PMID 2528684 DOI: 10.1128/Mcb.9.9.3603 |
0.433 |
|
1989 |
Majumder AL, Akins RA, Wilkinson JG, Kelley RL, Snook AJ, Lambowitz AM. Involvement of tyrosyl-tRNA synthetase in splicing of group I introns in Neurospora crassa mitochondria: biochemical and immunochemical analyses of splicing activity. Molecular and Cellular Biology. 9: 2089-104. PMID 2526294 DOI: 10.1128/Mcb.9.5.2089 |
0.425 |
|
1989 |
Lambowitz AM, Sabourin JR, Bertrand H, Nickels R, McIntosh L. Immunological identification of the alternative oxidase of Neurospora crassa mitochondria. Molecular and Cellular Biology. 9: 1362-4. PMID 2524649 DOI: 10.1128/Mcb.9.3.1362 |
0.334 |
|
1989 |
Akins RA, Kelley RL, Lambowitz AM. Characterization of mutant mitochondrial plasmids of Neurospora spp. that have incorporated tRNAs by reverse transcription Molecular and Cellular Biology. 9: 678-691. PMID 2469004 DOI: 10.1128/Mcb.9.2.678 |
0.511 |
|
1988 |
Akins RA, Grant DM, Stohl LL, Bottorff DA, Nargang FE, Lambowitz AM. Nucleotide sequence of the Varkud mitochondrial plasmid of Neurospora and synthesis of a hybrid transcript with a 5' leader derived from mitochondrial RNA. Journal of Molecular Biology. 204: 1-25. PMID 3216387 DOI: 10.1016/0022-2836(88)90594-3 |
0.53 |
|
1988 |
Mann BJ, Akins RA, Lambowitz AM, Metzenberg RL. The structural gene for a phosphorus-repressible phosphate permease in Neurospora crassa can complement a mutation in positive regulatory gene nuc-1 Molecular and Cellular Biology. 8: 1376-1379. PMID 2966896 DOI: 10.1128/MCB.8.3.1376 |
0.347 |
|
1988 |
Kuiper MT, Lambowitz AM. A novel reverse transcriptase activity associated with mitochondrial plasmids of Neurospora. Cell. 55: 693-704. PMID 2460246 DOI: 10.1016/0092-8674(88)90228-0 |
0.537 |
|
1987 |
Akins RA, Lambowitz AM. A protein required for splicing group I introns in Neurospora mitochondria is mitochondrial tyrosyl-tRNA synthetase or a derivative thereof Cell. 50: 331-345. PMID 3607872 DOI: 10.1016/0092-8674(87)90488-0 |
0.459 |
|
1987 |
Paietta JV, Akins RA, Lambowitz AM, Marzluf GA. Molecular cloning and characterization of the cys-3 regulatory gene of Neurospora crassa Molecular and Cellular Biology. 7: 2506-2511. PMID 2886908 DOI: 10.1128/Mcb.7.7.2506 |
0.332 |
|
1986 |
Garriga G, Lambowitz AM, Inoue T, Cech TR. Mechanism of recognition of the 5' splice site in self-splicing group I introns. Nature. 322: 86-9. PMID 3636598 DOI: 10.1038/322086A0 |
0.526 |
|
1986 |
Lambowitz AM, Akins RA, Kelley RL, Pande S, Nargang FE. Mitochondrial plasmids of Neurospora and other filamentous fungi Basic Life Sciences. 40: 83-92. PMID 3032148 DOI: 10.1007/978-1-4684-5251-8_7 |
0.356 |
|
1986 |
Akins RA, Kelley RL, Lambowitz AM. Mitochondrial plasmids of neurospora: Integration into mitochondrial DNA and evidence for reverse transcription in mitochondria Cell. 47: 505-516. PMID 3022934 DOI: 10.1016/0092-8674(86)90615-X |
0.486 |
|
1986 |
Garriga G, Lambowitz AM. Protein-dependent splicing of a group I intron in ribonucleoprotein particles and soluble fractions. Cell. 46: 669-80. PMID 2427199 DOI: 10.1016/0092-8674(86)90342-9 |
0.481 |
|
1985 |
Akins RA, Lambowitz AM. General method for cloning Neurospora crassa nuclear genes by complementation of mutants Molecular and Cellular Biology. 5: 2272-2278. PMID 2942762 DOI: 10.1128/Mcb.5.9.2272 |
0.324 |
|
1985 |
Collins RA, Lambowitz AM. RNA splicing in Neurospora mitochondria. Defective splicing of mitochondrial mRNA precursors in the nuclear mutant cyt18-1 Journal of Molecular Biology. 184: 413-428. PMID 2413216 DOI: 10.1016/0022-2836(85)90291-8 |
0.503 |
|
1984 |
Stohl LL, Akins RA, Lambowitz AM. Characterization of deletion derivatives of an autonomously replicating Neurospora plasmid Nucleic Acids Research. 12: 6169-6178. PMID 6236427 DOI: 10.1093/Nar/12.15.6169 |
0.364 |
|
1984 |
Akins RA, Lambowitz AM. The [poky] mutant of Neurospora contains a 4-base-pair deletion at the 5' end of the mitochondrial small rRNA Proceedings of the National Academy of Sciences of the United States of America. 81: 3791-3795. PMID 6233613 DOI: 10.1073/Pnas.81.12.3791 |
0.419 |
|
1984 |
Garriga G, Bertrand H, Lambowitz AM. RNA splicing in Neurospora mitochondria: nuclear mutants defective in both splicing and 3' end synthesis of the large rRNA. Cell. 36: 623-34. PMID 6230156 DOI: 10.1016/0092-8674(84)90342-8 |
0.511 |
|
1984 |
Stohl LL, Lambowitz AM. A colony filter-hybridization procedure for the filamentous fungus Neurospora crassa. Analytical Biochemistry. 134: 82-5. PMID 6229196 DOI: 10.1016/0003-2697(83)90266-X |
0.307 |
|
1984 |
Garriga G, Lambowitz AM. RNA splicing in neurospora mitochondria: self-splicing of a mitochondrial intron in vitro. Cell. 39: 631-41. PMID 6096015 DOI: 10.1016/0092-8674(84)90470-7 |
0.493 |
|
1984 |
Grant DM, Lambowitz AM, Rambosek JA, Kinsey JA. Transformation of Neurospora crassa with recombinant plasmids containing the cloned glutamate dehydrogenase (am) gene: evidence for autonomous replication of the transforming plasmid. Molecular and Cellular Biology. 4: 2041-51. PMID 6095037 DOI: 10.1128/Mcb.4.10.2041 |
0.362 |
|
1984 |
Nargang FE, Bell JB, Stohl LL, Lambowitz AM. The DNA sequence and genetic organization of a Neurospora mitochondrial plasmid suggest a relationship to introns and mobile elements. Cell. 38: 441-53. PMID 6088081 DOI: 10.1016/0092-8674(84)90499-9 |
0.464 |
|
1983 |
Wollenzien PL, Cantor CR, Grant DM, Lambowitz AM. RNA splicing in neurospora mitochondria: structure of the unspliced 35S precursor ribosomal RNA detected by psoralen cross-linking. Cell. 32: 397-407. PMID 6825174 DOI: 10.1016/0092-8674(83)90459-2 |
0.499 |
|
1983 |
Stohl LL, Lambowitz AM. Construction of a shuttle vector for the filamentous fungus Neurospora crassa. Proceedings of the National Academy of Sciences of the United States of America. 80: 1058-62. PMID 6302667 DOI: 10.1073/Pnas.80.4.1058 |
0.349 |
|
1983 |
Collins RA, Lambowitz AM. Structural variations and optional introns in the mitochondrial DNAs of Neurospora strains isolated from nature Plasmid. 9: 53-70. PMID 6300945 DOI: 10.1016/0147-619X(83)90031-8 |
0.367 |
|
1983 |
Lapolla RJ, Lambowitz AM. Mitochondrial ribosome assembly in Neurospora. Structural analysis of mature and partially assembled ribosomal subunits by equilibrium centrifugation in CsCl gradients. The Journal of Cell Biology. 95: 267-77. PMID 6216256 DOI: 10.1083/Jcb.95.1.267 |
0.35 |
|
1982 |
Bertrand H, Bridge P, Collins RA, Garriga G, Lambowitz AM. RNA splicing in Neurospora mitochondria. Characterization of new nuclear mutants with defects in splicing the mitochondrial large rRNA. Cell. 29: 517-26. PMID 7116448 DOI: 10.1016/0092-8674(82)90168-4 |
0.494 |
|
1982 |
Stohl LL, Collins RA, Cole MD, Lambowitz AM. Characterization of two new plasmid DNAs found in mitochondria of wild-type Neurospora intermedia strains. Nucleic Acids Research. 10: 1439-58. PMID 6280144 DOI: 10.1093/Nar/10.5.1439 |
0.39 |
|
1982 |
Garriga G, Collins RA, Grant DM, Lambowitz AM, Bertrand H. Mitochondrial RNA Splicing in Neurospora crassa Cold Spring Harbor Monograph Archive. 12: 381-390. DOI: 10.1101/087969145.12.381 |
0.452 |
|
1981 |
Bertrand H, Collins RA, Stohl LL, Goewert RR, Lambowitz AM. Deletion mutants of Neurospora crassa mitochondrial DNA and their relationship to the "stop-start" growth phenotype. Proceedings of the National Academy of Sciences of the United States of America. 77: 6032-6. PMID 6449700 DOI: 10.1073/Pnas.77.10.6032 |
0.339 |
|
1981 |
Grimm MF, Cole MD, Lambowitz AM. Ribonucleic acid splicing in Neurospora Mitochondria: secondary structure of the 35S ribosomal precursor ribonucleic acid investigated by digestion with ribonuclease III and by electron microscopy. Biochemistry. 20: 2836-42. PMID 6264946 DOI: 10.1021/Bi00513A020 |
0.534 |
|
1981 |
Collins RA, Stohl LL, Cole MD, Lambowitz AM. Characterization of a novel plasmid DNA found in mitochondria of N. crassa. Cell. 24: 443-52. PMID 6263496 DOI: 10.1016/0092-8674(81)90335-4 |
0.488 |
|
1981 |
Collins RA, Bertrand H, LaPolla RJ, Lambowitz AM. A novel extranuclear mutant of Neurospora with a temperature-sensitive defect in mitochondrial protein synthesis and mitochondrial ATPase. Molecular & General Genetics : Mgg. 181: 13-9. PMID 6261083 DOI: 10.1007/Bf00338998 |
0.323 |
|
1981 |
Collins RA, Lambowitz AM. Characterization of a variant Neurospora crassa mitochondrial DNA which contains tandem reiterations of a 1.9 kb sequence Current Genetics. 4: 131-133. DOI: 10.1007/Bf00365691 |
0.372 |
|
1980 |
Collins RA, Bertrand H, LaPolla RJ, Lambowitz AM. Mitochondrial ribosome assembly in Neurospora crassa: mutants with defects in mitochondrial ribosome assembly. Molecular & General Genetics : Mgg. 177: 73-84. PMID 161342 DOI: 10.1007/Bf00267255 |
0.436 |
|
1980 |
Grimm MF, Lambowitz AM. The 32 S RNA of Neurospora crassa mitochondria is not a precursor of the mitochondrial ribosomal RNAs. Journal of Molecular Biology. 134: 667-72. PMID 161331 DOI: 10.1016/0022-2836(79)90373-5 |
0.437 |
|
1980 |
Mannella CA, Goewert RR, Lambowitz AM. Characterization of variant Neurospora crassa mitochondrial DNAs which contain tandem reiterations. Cell. 18: 1197-207. PMID 160287 DOI: 10.1016/0092-8674(79)90232-0 |
0.404 |
|
1979 |
Lambowitz AM. Preparation and analysis of mitochondrial ribosomes. Methods in Enzymology. 59: 421-33. PMID 440084 DOI: 10.1016/0076-6879(79)59103-4 |
0.343 |
|
1979 |
Lambowitz AM, LaPolla RJ, Collins RA. Mitochondrial ribosome assembly in Neurospora. Two-dimensional gel electrophoretic analysis of mitochondrial ribosomal proteins. The Journal of Cell Biology. 82: 17-31. PMID 158027 DOI: 10.1083/Jcb.82.1.17 |
0.37 |
|
1979 |
Mannella CA, Collins RA, Green MR, Lambowitz AM. Defective splicing of mitochondrial rRNA in cytochrome-deficient nuclear mutants of Neurospora crassa. Proceedings of the National Academy of Sciences of the United States of America. 76: 2635-9. PMID 156923 DOI: 10.1073/Pnas.76.6.2635 |
0.494 |
|
1978 |
Mannella CA, Lambowitz A. Interaction of wild-type and poky mitochondrial DNA in heterokaryons of Neurospora. Biochemical and Biophysical Research Communications. 80: 673-9. PMID 147083 DOI: 10.1016/0006-291X(78)91621-2 |
0.401 |
|
1978 |
LaPolla RJ, Lambowitz AM. Mitochondrial ribosome assembly in Neurospora crassa. Chloramphenicol inhibits the maturation of small ribosomal subunits. Journal of Molecular Biology. 116: 189-205. PMID 146091 DOI: 10.1016/0022-2836(77)90212-1 |
0.427 |
|
1976 |
Lambowitz AM, Luck DJ. Studies on the poky mutant of eurospora crassa. Fingerprint analysis of mitochondrial ribosomal RNA. The Journal of Biological Chemistry. 251: 3081-95. PMID 178661 |
0.682 |
|
1976 |
Lambowitz AM, Chua NH, Luck DJ. Mitochondrial ribosome assembly in Neurospora. Preparation of mitochondrial ribosomal precursor particles, site of synthesis of mitochondrial ribosomal proteins and studies on the poky mutant. Journal of Molecular Biology. 107: 223-53. PMID 137320 DOI: 10.1016/S0022-2836(76)80003-4 |
0.658 |
|
1975 |
Lambowitz AM, Luck DJ. Letter: Methylation of mitochondrial RNA species in the wild-type and poky strains of Neurospora crassa. Journal of Molecular Biology. 96: 207-14. PMID 125795 DOI: 10.1016/0022-2836(75)90192-8 |
0.635 |
|
1972 |
Lambowitz AM, Slayman CW, Slayman CL, Bonner WD. The electron transport components of wild type and poky strains of Neurospora crassa. The Journal of Biological Chemistry. 247: 1536-45. PMID 4401060 |
0.468 |
|
1972 |
Lambowitz AM, Slayman CW. Effect of pyrrolnitrin on electron transport and oxidative phosphorylation in mitochondria isolated from Neurospora crassa. Journal of Bacteriology. 112: 1020-2. PMID 4343822 DOI: 10.1128/Jb.112.2.1020-1022.1972 |
0.531 |
|
1972 |
Lambowitz AM, Smith EW, Slayman CW. Oxidative phosphorylation in Neurospora mitochondria. Studies on wild type, poky, and chloramphenicol-induced wild type. The Journal of Biological Chemistry. 247: 4859-65. PMID 4340703 |
0.492 |
|
1972 |
Lambowitz AM, Smith EW, Slayman CW. Electron transport in Neurospora mitochondria. Studies on wild type and poky. The Journal of Biological Chemistry. 247: 4850-8. PMID 4340702 |
0.485 |
|
1971 |
Lambowitz AM, Slayman CW. Cyanide-resistant respiration in Neurospora crassa. Journal of Bacteriology. 108: 1087-96. PMID 4333318 DOI: 10.1128/Jb.108.3.1087-1096.1971 |
0.542 |
|
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