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Ramon Gonzalez - Publications

Affiliations: 
2001 Chemical Engineering University of Chile, Santiago, Región Metropolitana, Chile 
 2001-2002 Microbiology and Cell Science University of Florida, Gainesville, Gainesville, FL, United States 
 2002-2005 Chemical & Biological Engineering Iowa State University, Ames, IA, United States 
 2005-2018 Chemical & Biomolecular Engineering Rice University, Houston, TX 
 2018- Chemical & Biomedical Engineering University of South Florida, Tampa, FL, United States 
Website:
https://www.gonzalezresearchgroup.com/
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73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lee SH, Hu Y, Chou A, Chen J, Gonzalez R. Metabolic flux optimization of iterative pathways through orthogonal gene expression control: Application to the β-oxidation reversal. Metabolic Engineering. PMID 38387675 DOI: 10.1016/j.ymben.2024.02.007  0.356
2023 Nattermann M, Wenk S, Pfister P, He H, Lee SH, Szymanski W, Guntermann N, Zhu F, Nickel L, Wallner C, Zarzycki J, Paczia N, Gaißert N, Franciò G, Leitner W, ... Gonzalez R, et al. Engineering a new-to-nature cascade for phosphate-dependent formate to formaldehyde conversion in vitro and in vivo. Nature Communications. 14: 2682. PMID 37160875 DOI: 10.1038/s41467-023-38072-w  0.311
2022 Vögeli B, Schulz L, Garg S, Tarasava K, Clomburg JM, Lee SH, Gonnot A, Moully EH, Kimmel BR, Tran L, Zeleznik H, Brown SD, Simpson SD, Mrksich M, Karim AS, ... Gonzalez R, et al. Cell-free prototyping enables implementation of optimized reverse β-oxidation pathways in heterotrophic and autotrophic bacteria. Nature Communications. 13: 3058. PMID 35650184 DOI: 10.1038/s41467-022-30571-6  0.312
2022 Hu L, Guo S, Wang B, Fu R, Fan D, Jiang M, Fei Q, Gonzalez R. Bio-valorization of C1 gaseous substrates into bioalcohols: Potentials and challenges in reducing carbon emissions. Biotechnology Advances. 59: 107954. PMID 35417775 DOI: 10.1016/j.biotechadv.2022.107954  0.3
2022 Tarasava K, Lee SH, Chen J, Köpke M, Jewett MC, Gonzalez R. Reverse β-oxidation pathways for efficient chemical production. Journal of Industrial Microbiology & Biotechnology. PMID 35218187 DOI: 10.1093/jimb/kuac003  0.392
2021 Clomburg JM, Cintolesi A, Gonzalez R. In silico and in␣vivo analyses reveal key metabolic pathways enabling the fermentative utilization of glycerol in Escherichia coli. Microbial Biotechnology. PMID 34699695 DOI: 10.1111/1751-7915.13938  0.315
2021 Chou A, Lee SH, Zhu F, Clomburg JM, Gonzalez R. An orthogonal metabolic framework for one-carbon utilization. Nature Metabolism. 3: 1385-1399. PMID 34675440 DOI: 10.1038/s42255-021-00453-0  0.379
2021 Wang Y, Nguyen N, Lee SH, Wang Q, May JA, Gonzalez R, Cirino PC. Engineering Escherichia coli for anaerobic alkane activation: Biosynthesis of (1-methylalkyl)succinates. Biotechnology and Bioengineering. PMID 34633065 DOI: 10.1002/bit.27956  0.348
2019 Chou A, Clomburg JM, Qian S, Gonzalez R. 2-Hydroxyacyl-CoA lyase catalyzes acyloin condensation for one-carbon bioconversion. Nature Chemical Biology. PMID 31383974 DOI: 10.1038/S41589-019-0328-0  0.406
2019 Clomburg JM, Qian S, Tan Z, Cheong S, Gonzalez R. The isoprenoid alcohol pathway, a synthetic route for isoprenoid biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31186357 DOI: 10.1073/Pnas.1821004116  0.444
2019 Qian S, Clomburg JM, Gonzalez R. Engineering Escherichia coli as a platform for the in vivo synthesis of prenylated aromatics. Biotechnology and Bioengineering. PMID 30659582 DOI: 10.1002/Bit.26932  0.461
2018 Tan Z, Clomburg J, Gonzalez R. Synthetic pathway for the production of olivetolic acid in Escherichia coli. Acs Synthetic Biology. PMID 29976061 DOI: 10.1021/Acssynbio.8B00075  0.463
2018 Katz L, Chen YY, Gonzalez R, Peterson TC, Zhao H, Baltz RH. Synthetic biology advances and applications in the biotechnology industry: a perspective. Journal of Industrial Microbiology & Biotechnology. PMID 29915997 DOI: 10.1007/S10295-018-2056-Y  0.36
2018 Garg S, Clomburg JM, Gonzalez R. A modular approach for high-flux lactic acid production from methane in an industrial medium using engineered Methylomicrobium buryatense 5GB1. Journal of Industrial Microbiology & Biotechnology. PMID 29675615 DOI: 10.1007/S10295-018-2035-3  0.418
2018 Cheong S, Clomburg JM, Gonzalez R. A synthetic pathway for the production of 2-hydroxyisovaleric acid in Escherichia coli. Journal of Industrial Microbiology & Biotechnology. PMID 29330665 DOI: 10.1007/S10295-018-2005-9  0.481
2018 Kim S, Gonzalez R. Selective production of decanoic acid from iterative reversal of β-oxidation pathway. Biotechnology and Bioengineering. PMID 29315475 DOI: 10.1002/Bit.26540  0.451
2017 Clomburg JM, Contreras SC, Chou A, Siegel JB, Gonzalez R. Combination of type II fatty acid biosynthesis enzymes and thiolases supports a functional β-oxidation reversal. Metabolic Engineering. PMID 29146470 DOI: 10.1016/J.Ymben.2017.11.003  0.411
2017 Clomburg JM, Crumbley AM, Gonzalez R. Industrial biomanufacturing: The future of chemical production. Science (New York, N.Y.). 355. PMID 28059717 DOI: 10.1126/Science.Aag0804  0.354
2016 Kim S, Cheong S, Chou A, Gonzalez R. Engineered fatty acid catabolism for fuel and chemical production. Current Opinion in Biotechnology. 42: 206-215. PMID 27636720 DOI: 10.1016/J.Copbio.2016.07.004  0.466
2016 Curiel JA, Salvadó Z, Tronchoni J, Morales P, Rodrigues AJ, Quirós M, Gonzalez R. Identification of target genes to control acetate yield during aerobic fermentation with Saccharomyces cerevisiae. Microbial Cell Factories. 15: 156. PMID 27627879 DOI: 10.1186/s12934-016-0555-y  0.334
2016 Cheong S, Clomburg JM, Gonzalez R. Energy- and carbon-efficient synthesis of functionalized small molecules in bacteria using non-decarboxylative Claisen condensation reactions. Nature Biotechnology. PMID 27088721 DOI: 10.1038/Nbt.3505  0.377
2016 Kim S, Cheong S, Gonzalez R. Engineering Escherichia coli for the synthesis of short- and medium-chain α,β-unsaturated carboxylic acids. Metabolic Engineering. PMID 26996381 DOI: 10.1016/J.Ymben.2016.03.005  0.406
2015 Vergara M, Berrios J, Martínez I, Díaz-Barrera A, Acevedo C, Reyes JG, Gonzalez R, Altamirano C. Endoplasmic Reticulum-Associated rht-PA Processing in CHO Cells: Influence of Mild Hypothermia and Specific Growth Rates in Batch and Chemostat Cultures. Plos One. 10: e0144224. PMID 26659083 DOI: 10.1371/Journal.Pone.0144224  0.31
2015 Rodríguez-Moyá M, Gonzalez R. Proteomic analysis of the response of Escherichia coli to short-chain fatty acids. Journal of Proteomics. 122: 86-99. PMID 25845584 DOI: 10.1016/J.Jprot.2015.03.033  0.392
2015 Kim S, Clomburg JM, Gonzalez R. Synthesis of medium-chain length (C6-C10) fuels and chemicals via β-oxidation reversal in Escherichia coli. Journal of Industrial Microbiology & Biotechnology. 42: 465-75. PMID 25645093 DOI: 10.1007/S10295-015-1589-6  0.423
2015 Clomburg JM, Blankschien MD, Vick JE, Chou A, Kim S, Gonzalez R. Integrated engineering of β-oxidation reversal and ω-oxidation pathways for the synthesis of medium chain ω-functionalized carboxylic acids. Metabolic Engineering. 28: 202-12. PMID 25638687 DOI: 10.1016/J.Ymben.2015.01.007  0.429
2015 Vick JE, Clomburg JM, Blankschien MD, Chou A, Kim S, Gonzalez R. Escherichia coli enoyl-acyl carrier protein reductase (FabI) supports efficient operation of a functional reversal of β-oxidation cycle. Applied and Environmental Microbiology. 81: 1406-16. PMID 25527535 DOI: 10.1128/Aem.03521-14  0.411
2014 Haynes CA, Gonzalez R. Rethinking biological activation of methane and conversion to liquid fuels. Nature Chemical Biology. 10: 331-9. PMID 24743257 DOI: 10.1038/Nchembio.1509  0.33
2014 Vergara M, Becerra S, Berrios J, Osses N, Reyes J, Rodríguez-Moyá M, Gonzalez R, Altamirano C. Differential effect of culture temperature and specific growth rate on CHO cell behavior in chemostat culture. Plos One. 9: e93865. PMID 24699760 DOI: 10.1371/Journal.Pone.0093865  0.336
2014 Cintolesi A, Clomburg JM, Gonzalez R. In silico assessment of the metabolic capabilities of an engineered functional reversal of the β-oxidation cycle for the synthesis of longer-chain (C≥4) products. Metabolic Engineering. 23: 100-15. PMID 24569100 DOI: 10.1016/J.Ymben.2014.02.011  0.508
2014 Conrado RJ, Gonzalez R. Chemistry. Envisioning the bioconversion of methane to liquid fuels. Science (New York, N.Y.). 343: 621-3. PMID 24503844 DOI: 10.1126/Science.1246929  0.34
2013 Quirós M, Martínez-Moreno R, Albiol J, Morales P, Vázquez-Lima F, Barreiro-Vázquez A, Ferrer P, Gonzalez R. Metabolic flux analysis during the exponential growth phase of Saccharomyces cerevisiae in wine fermentations. Plos One. 8: e71909. PMID 23967264 DOI: 10.1371/journal.pone.0071909  0.345
2013 Rastogi G, Gurram RN, Bhalla A, Gonzalez R, Bischoff KM, Hughes SR, Kumar S, Sani RK. Presence of glucose, xylose, and glycerol fermenting bacteria in the deep biosphere of the former Homestake gold mine, South Dakota. Frontiers in Microbiology. 4: 18. PMID 23919089 DOI: 10.3389/Fmicb.2013.00018  0.379
2013 Mattam AJ, Clomburg JM, Gonzalez R, Yazdani SS. Fermentation of glycerol and production of valuable chemical and biofuel molecules. Biotechnology Letters. 35: 831-42. PMID 23690047 DOI: 10.1007/S10529-013-1240-4  0.444
2013 Cintolesi A, Rodríguez-Moyá M, Gonzalez R. Fatty acid oxidation: systems analysis and applications. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 5: 575-85. PMID 23661533 DOI: 10.1002/Wsbm.1226  0.377
2013 Mazumdar S, Blankschien MD, Clomburg JM, Gonzalez R. Efficient synthesis of L-lactic acid from glycerol by metabolically engineered Escherichia coli. Microbial Cell Factories. 12: 7. PMID 23347598 DOI: 10.1186/1475-2859-12-7  0.417
2013 Blankschien MD, Pretzer LA, Huschka R, Halas NJ, Gonzalez R, Wong MS. Light-triggered biocatalysis using thermophilic enzyme - Gold nanoparticle complexes Acs Nano. 7: 654-663. PMID 23237546 DOI: 10.1021/Nn3048445  0.314
2013 Clomburg JM, Gonzalez R. Anaerobic fermentation of glycerol: a platform for renewable fuels and chemicals. Trends in Biotechnology. 31: 20-8. PMID 23178075 DOI: 10.1016/J.Tibtech.2012.10.006  0.425
2013 Gonzalez R. Metabolic engineering: Use of system-level approaches and application to fuel production in Escherichia coli Electronic Journal of Biotechnology. 16: 17-17. DOI: 10.2225/Vol16-Issue3-Fulltext-14  0.44
2012 Clomburg JM, Vick JE, Blankschien MD, Rodríguez-Moyá M, Gonzalez R. A synthetic biology approach to engineer a functional reversal of the β-oxidation cycle. Acs Synthetic Biology. 1: 541-54. PMID 23656231 DOI: 10.1021/Sb3000782  0.453
2012 Park J, Rodríguez-Moyá M, Li M, Pichersky E, San KY, Gonzalez R. Synthesis of methyl ketones by metabolically engineered Escherichia coli Journal of Industrial Microbiology and Biotechnology. 39: 1703-1712. PMID 22850984 DOI: 10.1007/S10295-012-1178-X  0.402
2012 Cintolesi A, Clomburg JM, Rigou V, Zygourakis K, Gonzalez R. Quantitative analysis of the fermentative metabolism of glycerol in Escherichia coli. Biotechnology and Bioengineering. 109: 187-98. PMID 21858785 DOI: 10.1002/Bit.23309  0.459
2012 Vergara M, Becerra S, Berrios J, Gonzalez R, Reyes J, Altamirano C. Application of inhibitors of the translation process and ERAD pathways leading to increased specific productivity of t-PA in CHO cells in continuous culture New Biotechnology. 29. DOI: 10.1016/J.Nbt.2012.08.587  0.319
2011 Posada JA, Cardona CA, Gonzalez R. Analysis of the production process of optically pure D-lactic acid from raw glycerol using engineered Escherichia coli strains. Applied Biochemistry and Biotechnology. 166: 680-99. PMID 22127808 DOI: 10.1007/S12010-011-9458-X  0.388
2011 Dellomonaco C, Clomburg JM, Miller EN, Gonzalez R. Engineered reversal of the β-oxidation cycle for the synthesis of fuels and chemicals. Nature. 476: 355-9. PMID 21832992 DOI: 10.1038/Nature10333  0.712
2011 Zhu H, Gonzalez R, Bobik TA. Coproduction of acetaldehyde and hydrogen during glucose fermentation by Escherichia coli. Applied and Environmental Microbiology. 77: 6441-50. PMID 21803884 DOI: 10.1128/Aem.05358-11  0.412
2011 Clomburg JM, Gonzalez R. Metabolic engineering of Escherichia coli for the production of 1,2-propanediol from glycerol Biotechnology and Bioengineering. 108: 867-879. PMID 21404260 DOI: 10.1002/Bit.22993  0.515
2011 Becerra S, Vergara M, González R, Osses N, Altamirano C. Condition of mild hypothermia does not promote an increase in specific productivity of recombinant protein at high specific growth rate Current Opinion in Biotechnology. 22. DOI: 10.1016/J.Copbio.2011.05.081  0.313
2011 Berrios J, Altamirano C, Osses N, Gonzalez R. Continuous CHO cell cultures with improved recombinant protein productivity by using mannose as carbon source: Metabolic analysis and scale-up simulation Chemical Engineering Science. 66: 2431-2439. DOI: 10.1016/J.Ces.2011.03.011  0.355
2011 Choudhary MK, Yoon JM, Gonzalez R, Shanks JV. Re-examination of Metabolic Fluxes in Escherichia coli during Anaerobic Fermentation of Glucose Using 13C Labeling Experiments and 2-dimensional Nuclear Magnetic Resonance (NMR) Spectroscopy Biotechnology and Bioprocess Engineering. 16: 419-437. DOI: 10.1007/S12257-010-0449-5  0.363
2010 Murarka A, Clomburg JM, Moran S, Shanks JV, Gonzalez R. Metabolic analysis of wild-type Escherichia coli and a pyruvate dehydrogenase complex (PDHC)-deficient derivative reveals the role of PDHC in the fermentative metabolism of glucose. The Journal of Biological Chemistry. 285: 31548-58. PMID 20667837 DOI: 10.1074/Jbc.M110.121095  0.443
2010 Blankschien MD, Clomburg JM, Gonzalez R. Metabolic engineering of Escherichia coli for the production of succinate from glycerol. Metabolic Engineering. 12: 409-19. PMID 20601068 DOI: 10.1016/j.ymben.2010.06.002  0.388
2010 Dellomonaco C, Rivera C, Campbell P, Gonzalez R. Engineered respiro-fermentative metabolism for the production of biofuels and biochemicals from fatty acid-rich feedstocks. Applied and Environmental Microbiology. 76: 5067-78. PMID 20525863 DOI: 10.1128/AEM.00046-10  0.418
2010 Mazumdar S, Clomburg JM, Gonzalez R. Escherichia coli strains engineered for homofermentative production of D-lactic acid from glycerol. Applied and Environmental Microbiology. 76: 4327-36. PMID 20472739 DOI: 10.1128/Aem.00664-10  0.444
2010 Murarka A, Clomburg JM, Gonzalez R. Metabolic flux analysis of wild-type Escherichia coli and mutants deficient in pyruvate-dissimilating enzymes during the fermentative metabolism of glucuronate. Microbiology (Reading, England). 156: 1860-72. PMID 20167619 DOI: 10.1099/Mic.0.036251-0  0.405
2010 Clomburg JM, Gonzalez R. Biofuel production in Escherichia coli: the role of metabolic engineering and synthetic biology. Applied Microbiology and Biotechnology. 86: 419-34. PMID 20143230 DOI: 10.1007/s00253-010-2446-1  0.404
2010 Dellomonaco C, Fava F, Gonzalez R. The path to next generation biofuels: successes and challenges in the era of synthetic biology. Microbial Cell Factories. 9: 3. PMID 20089184 DOI: 10.1186/1475-2859-9-3  0.329
2010 Dellomonaco C, Fava F, Gonzalez R. The path to next generation biofuels: successes and challenges in the era of synthetic biology. Microbial Cell Factories. 9: 3. PMID 20089184 DOI: 10.1186/1475-2859-9-3  0.329
2010 Gonzalez R, Campbell P, Wong M. Production of ethanol from thin stillage by metabolically engineered Escherichia coli Biotechnology Letters. 32: 405-411. PMID 19898751 DOI: 10.1007/S10529-009-0159-2  0.465
2010 Dellomonaco C, Rivera C, Campbell P, Gonzalez R. Engineered Respiro-Fermentative Metabolism for the Production of Biofuels and Biochemicals from Fatty Acid-Rich Feedstocks Applied and Environmental Microbiology. 76: 5067-5078. DOI: 10.1128/Aem.00046-10  0.506
2010 Blankschien MD, Clomburg JM, Gonzalez R. Metabolic engineering of Escherichia coli for the production of succinate from glycerol Metabolic Engineering. 12: 409-419. DOI: 10.1016/J.Ymben.2010.06.002  0.485
2010 Clomburg JM, Gonzalez R. Biofuel production in Escherichia coli: the role of metabolic engineering and synthetic biology Applied Microbiology and Biotechnology. 86: 419-434. DOI: 10.1007/S00253-010-2446-1  0.494
2009 Gupta A, Murarka A, Campbell P, Gonzalez R. Anaerobic fermentation of glycerol in Paenibacillus macerans: metabolic pathways and environmental determinants. Applied and Environmental Microbiology. 75: 5871-83. PMID 19617389 DOI: 10.1128/Aem.01246-09  0.474
2009 Durnin G, Clomburg J, Yeates Z, Alvarez PJ, Zygourakis K, Campbell P, Gonzalez R. Understanding and harnessing the microaerobic metabolism of glycerol in Escherichia coli. Biotechnology and Bioengineering. 103: 148-61. PMID 19189409 DOI: 10.1002/Bit.22246  0.485
2008 Shams Yazdani S, Gonzalez R. Engineering Escherichia coli for the efficient conversion of glycerol to ethanol and co-products. Metabolic Engineering. 10: 340-51. PMID 18840539 DOI: 10.1016/J.Ymben.2008.08.005  0.42
2008 Gonzalez R, Murarka A, Dharmadi Y, Yazdani SS. A new model for the anaerobic fermentation of glycerol in enteric bacteria: trunk and auxiliary pathways in Escherichia coli. Metabolic Engineering. 10: 234-45. PMID 18632294 DOI: 10.1016/J.Ymben.2008.05.001  0.443
2008 Murarka A, Dharmadi Y, Yazdani SS, Gonzalez R. Fermentative utilization of glycerol by Escherichia coli and its implications for the production of fuels and chemicals. Applied and Environmental Microbiology. 74: 1124-35. PMID 18156341 DOI: 10.1128/Aem.02192-07  0.477
2007 Yazdani SS, Gonzalez R. Anaerobic fermentation of glycerol: a path to economic viability for the biofuels industry. Current Opinion in Biotechnology. 18: 213-9. PMID 17532205 DOI: 10.1016/J.Copbio.2007.05.002  0.428
2006 Dharmadi Y, Murarka A, Gonzalez R. Anaerobic fermentation of glycerol by Escherichia coli: a new platform for metabolic engineering. Biotechnology and Bioengineering. 94: 821-9. PMID 16715533 DOI: 10.1002/Bit.21025  0.493
2003 Gonzalez R, Tao H, Purvis JE, York SW, Shanmugam KT, Ingram LO. Gene array-based identification of changes that contribute to ethanol tolerance in ethanologenic Escherichia coli: Comparison of KO11 (parent) to LY01 (resistant mutant) Biotechnology Progress. 19: 612-623. PMID 12675606 DOI: 10.1021/Bp025658Q  0.552
2003 Gonzalez R, Andrews BA, Molitor J, Asenjo JA. Metabolic analysis of the synthesis of high levels of intracellular human SOD in Saccharomyces cerevisiae rhSOD 2060 411 SGA122. Biotechnology and Bioengineering. 82: 152-69. PMID 12584757 DOI: 10.1002/bit.10556  0.618
2002 Gonzalez R, Tao H, Shanmugam KT, York SW, Ingram LO. Global gene expression differences associated with changes in glycolytic flux and growth rate in Escherichia coli during the fermentation of glucose and xylose. Biotechnology Progress. 18: 6-20. PMID 11822894 DOI: 10.1021/Bp010121I  0.574
2001 Tao H, Gonzalez R, Martinez A, Rodriguez M, Ingram LO, Preston JF, Shanmugam KT. Engineering a homo-ethanol pathway in Escherichia coli: increased glycolytic flux and levels of expression of glycolytic genes during xylose fermentation. Journal of Bacteriology. 183: 2979-88. PMID 11325924 DOI: 10.1128/Jb.183.10.2979-2988.2001  0.559
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