| Year |
Citation |
Score |
| 2023 |
Coonahan E, Gage H, Chen D, Noormahomed EV, Buene TP, Mendes de Sousa I, Akrami K, Chambal L, Schooley RT, Winzeler EA, Cowell AN. Whole-genome surveillance identifies markers of drug resistance and novel genomic regions under selection in Mozambique. Mbio. e0176823. PMID 37750720 DOI: 10.1128/mbio.01768-23 |
0.695 |
|
| 2021 |
Murithi JM, Deni I, Pasaje CFA, Okombo J, Bridgford JL, Gnädig NF, Edwards RL, Yeo T, Mok S, Burkhard AY, Coburn-Flynn O, Istvan ES, Sakata-Kato T, Gomez-Lorenzo MG, Cowell AN, et al. The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance. Cell Chemical Biology. PMID 34233174 DOI: 10.1016/j.chembiol.2021.06.006 |
0.654 |
|
| 2021 |
Reader J, van der Watt ME, Taylor D, Le Manach C, Mittal N, Ottilie S, Theron A, Moyo P, Erlank E, Nardini L, Venter N, Lauterbach S, Bezuidenhout B, Horatscheck A, van Heerden A, ... ... Cowell AN, et al. Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box. Nature Communications. 12: 269. PMID 33431834 DOI: 10.1038/s41467-020-20629-8 |
0.592 |
|
| 2020 |
Fisher GM, Cobbold SA, Jezewski A, Carpenter EF, Arnold M, Cowell AN, Tjhin ET, Saliba KJ, Skinner-Adams TS, Lee MCS, Odom John A, Winzeler EA, McConville MJ, Poulsen SA, Andrews KT. The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides. Mbio. 11. PMID 33293381 DOI: 10.1128/mBio.02842-20 |
0.624 |
|
| 2020 |
Morahan BJ, Abrie C, Al-Hasani K, Batty MB, Corey V, Cowell AN, Niemand J, Winzeler EA, Birkholtz LM, Doerig C, Garcia-Bustos JF. Human Aurora kinase inhibitor Hesperadin reveals epistatic interaction between Plasmodium falciparum PfArk1 and PfNek1 kinases. Communications Biology. 3: 701. PMID 33219324 DOI: 10.1038/s42003-020-01424-z |
0.72 |
|
| 2019 |
Cowell AN, Winzeler EA. Advances in omics-based methods to identify novel targets for malaria and other parasitic protozoan infections. Genome Medicine. 11: 63. PMID 31640748 DOI: 10.1186/S13073-019-0673-3 |
0.72 |
|
| 2019 |
Cowell AN, Winzeler EA. The genomic architecture of antimalarial drug resistance. Briefings in Functional Genomics. PMID 31119263 DOI: 10.1093/Bfgp/Elz008 |
0.713 |
|
| 2019 |
LaMonte GM, Orjuela-Sanchez P, Calla J, Wang LT, Li S, Swann J, Cowell AN, Zou BY, Abdel-Haleem Mohamed AM, Villa Galarce ZH, Moreno M, Tong Rios C, Vinetz JM, Lewis N, Winzeler EA. Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection. Nature Communications. 10: 488. PMID 30700707 DOI: 10.1038/S41467-019-08349-0 |
0.668 |
|
| 2018 |
Cowell A, Winzeler E. Exploration of the Resistome and Druggable Genome Reveals New Mechanisms of Drug Resistance and Antimalarial Targets. Microbiology Insights. 11: 1178636118808529. PMID 30505148 DOI: 10.1177/1178636118808529 |
0.72 |
|
| 2018 |
Cowell AN, Valdivia HO, Bishop DK, Winzeler EA. Exploration of Plasmodium vivax transmission dynamics and recurrent infections in the Peruvian Amazon using whole genome sequencing. Genome Medicine. 10: 52. PMID 29973248 DOI: 10.1186/S13073-018-0563-0 |
0.597 |
|
| 2018 |
Llanos-Cuentas A, Casapia M, Chuquiyauri R, Hinojosa JC, Kerr N, Rosario M, Toovey S, Arch RH, Phillips MA, Rozenberg FD, Bath J, Ng CL, Cowell AN, Winzeler EA, Fidock DA, et al. Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study. The Lancet. Infectious Diseases. PMID 29909069 DOI: 10.1016/S1473-3099(18)30309-8 |
0.593 |
|
| 2018 |
Cowell AN, Istvan ES, Lukens AK, Gomez-Lorenzo MG, Vanaerschot M, Sakata-Kato T, Flannery EL, Magistrado P, Owen E, Abraham M, LaMonte G, Painter HJ, Williams RM, Franco V, Linares M, et al. Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics. Science (New York, N.Y.). 359: 191-199. PMID 29326268 DOI: 10.1126/Science.Aan4472 |
0.578 |
|
| 2017 |
Dhingra SK, Redhi D, Combrinck JM, Yeo T, Okombo J, Henrich PP, Cowell AN, Gupta P, Stegman ML, Hoke JM, Cooper RA, Winzeler E, Mok S, Egan TJ, Fidock DA. A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine. Mbio. 8. PMID 28487425 DOI: 10.1128/Mbio.00303-17 |
0.675 |
|
| 2017 |
Cowell AN, Loy DE, Sundararaman SA, Valdivia H, Fisch K, Lescano AG, Baldeviano GC, Durand S, Gerbasi V, Sutherland CJ, Nolder D, Vinetz JM, Hahn BH, Winzeler EA. Selective Whole-Genome Amplification Is a Robust Method That Enables Scalable Whole-Genome Sequencing of Plasmodium vivax from Unprocessed Clinical Samples. Mbio. 8. PMID 28174312 DOI: 10.1128/Mbio.02257-16 |
0.604 |
|
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