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Aaron A Hoskins - Publications

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
Area:
RNA, Splicing, Biochemistry, Biophysics, Single Molecule Fluorescence
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Carrocci TJ, DeMario S, He K, Zeps NJ, Harkner CT, Chanfreau G, Hoskins AA. Functional Analysis of the Zinc Finger Modules of the Splicing Factor Luc7. Biorxiv : the Preprint Server For Biology. PMID 38352541 DOI: 10.1101/2024.02.04.578419  0.369
2023 Lipinski KA, Senn KA, Zeps NJ, Hoskins AA. Biochemical and Genetic Evidence Supports Fyv6 as a Second-Step Splicing Factor in Saccharomyces cerevisiae. Rna (New York, N.Y.). PMID 37625852 DOI: 10.1261/rna.079607.123  0.407
2023 Lipinski KA, Senn KA, Zeps NJ, Hoskins AA. Biochemical and Genetic Evidence Supports Fyv6 as a Second-Step Splicing Factor in . Biorxiv : the Preprint Server For Biology. PMID 36778415 DOI: 10.1101/2023.01.30.526368  0.395
2022 Fu X, Kaur H, Rodgers ML, Montemayor EJ, Butcher SE, Hoskins AA. Identification of transient intermediates during spliceosome activation by single molecule fluorescence microscopy. Proceedings of the National Academy of Sciences of the United States of America. 119: e2206815119. PMID 36417433 DOI: 10.1073/pnas.2206815119  0.427
2022 Lipinski KA, Chi J, Chen X, Hoskins A, Brow DA. Yeast U6 snRNA made by RNA polymerase II is less stable but functional. Rna (New York, N.Y.). PMID 36195346 DOI: 10.1261/rna.079328.122  0.346
2022 Hansen SR, White DS, Scalf M, Corrêa IR, Smith LM, Hoskins AA. Multi-step recognition of potential 5' splice sites by the U1 snRNP. Elife. 11. PMID 35959885 DOI: 10.7554/eLife.70534  0.762
2022 Kaur H, van der Feltz C, Sun Y, Hoskins AA. Network theory reveals principles of spliceosome structure and dynamics. Structure (London, England : 1993). 30: 190-200.e2. PMID 34592160 DOI: 10.1016/j.str.2021.09.003  0.32
2021 Carrocci TJ, Hoskins AA. RNA processing: Fungal spliceosomes break the mold. Current Biology : Cb. 31: R1482-R1484. PMID 34813754 DOI: 10.1016/j.cub.2021.09.075  0.784
2021 Love SL, Hoskins AA. Stuck on UUUU: New splicing inhibitors enhance U2AF2-RNA binding. Cell Chemical Biology. 28: 1106-1108. PMID 34416141 DOI: 10.1016/j.chembiol.2021.07.021  0.423
2021 van der Feltz C, Nikolai B, Schneider C, Paulson JC, Fu X, Hoskins AA. Saccharomyces cerevisiae Ecm2 Modulates the Catalytic Steps of pre-mRNA Splicing. Rna (New York, N.Y.). PMID 33547186 DOI: 10.1261/rna.077727.120  0.419
2019 van der Feltz C, Hoskins AA. Structural and functional modularity of the U2 snRNP in pre-mRNA splicing. Critical Reviews in Biochemistry and Molecular Biology. 54: 443-465. PMID 31744343 DOI: 10.1080/10409238.2019.1691497  0.427
2019 Beier DH, Carrocci TJ, van der Feltz C, Tretbar US, Paulson JC, Grabowski N, Hoskins AA. Dynamics of the DEAD-box ATPase Prp5 RecA-like domains provide a conformational switch during spliceosome assembly. Nucleic Acids Research. 47: 10842-10851. PMID 31712821 DOI: 10.1093/nar/gkz765  0.777
2019 Hansen SR, Nikolai BJ, Spreacker PJ, Carrocci TJ, Hoskins AA. Chemical Inhibition of Pre-mRNA Splicing in Living Saccharomyces cerevisiae. Cell Chemical Biology. 26: 443-448.e3. PMID 30639260 DOI: 10.1016/j.chembiol.2018.11.008  0.76
2018 Carrocci TJ, Paulson JC, Hoskins AA. Functional analysis of Hsh155/SF3b1 interactions with the U2 snRNA/branch site duplex. Rna (New York, N.Y.). 24: 1028-1040. PMID 29752352 DOI: 10.1261/rna.065664.118  0.788
2017 Carrocci TJ, Lohe L, Ashton MJ, Höbartner C, Hoskins AA. Debranchase-resistant labeling of RNA using the 10DM24 deoxyribozyme and fluorescent modified nucleotides. Chemical Communications (Cambridge, England). PMID 28984884 DOI: 10.1039/C7Cc06703H  0.778
2017 Didychuk AL, Montemayor EJ, Carrocci TJ, DeLaitsch AT, Lucarelli SE, Westler WM, Brow DA, Hoskins AA, Butcher SE. Usb1 controls U6 snRNP assembly through evolutionarily divergent cyclic phosphodiesterase activities. Nature Communications. 8: 497. PMID 28887445 DOI: 10.1038/S41467-017-00484-W  0.806
2017 Larson JD, Hoskins AA. Dynamics and consequences of spliceosome E complex formation. Elife. 6. PMID 28829039 DOI: 10.7554/eLife.27592  0.778
2017 Panchapakesan SS, Ferguson ML, Hayden EJ, Chen X, Hoskins AA, Unrau PJ. Ribonucleoprotein Purification and Characterization using RNA Mango. Rna (New York, N.Y.). PMID 28747322 DOI: 10.1261/Rna.062166.117  0.451
2017 van der Feltz C, Hoskins AA. Methodologies for studying the spliceosome's RNA dynamics with single-molecule FRET. Methods (San Diego, Calif.). 125: 45-54. PMID 28529063 DOI: 10.1016/j.ymeth.2017.05.011  0.396
2017 Carrocci TJ, Zoerner DM, Paulson JC, Hoskins AA. SF3b1 mutations associated with myelodysplastic syndromes alter the fidelity of branchsite selection in yeast. Nucleic Acids Research. 45: 4837-4852. PMID 28062854 DOI: 10.1093/nar/gkw1349  0.787
2016 Rodgers ML, Didychuk AL, Butcher SE, Brow DA, Hoskins AA. A multi-step model for facilitated unwinding of the yeast U4/U6 RNA duplex. Nucleic Acids Research. PMID 27484481 DOI: 10.1093/Nar/Gkw686  0.351
2016 Hoskins AA, Rodgers ML, Friedman LJ, Gelles J, Moore MJ. Single molecule analysis reveals reversible and irreversible steps during spliceosome activation. Elife. 5. PMID 27244240 DOI: 10.7554/Elife.14166  0.712
2016 DeHaven AC, Norden IS, Hoskins AA. Lights, camera, action! Capturing the spliceosome and pre-mRNA splicing with single-molecule fluorescence microscopy. Wiley Interdisciplinary Reviews. Rna. 7: 683-701. PMID 27198613 DOI: 10.1002/wrna.1358  0.481
2015 Cornilescu G, Didychuk AL, Rodgers ML, Michael LA, Burke JE, Montemayor EJ, Hoskins AA, Butcher SE. Structural Analysis of Multi-Helical RNAs by NMR-SAXS/WAXS: Application to the U4/U6 di-snRNA. Journal of Molecular Biology. PMID 26655855 DOI: 10.1016/J.Jmb.2015.11.026  0.337
2015 Rodgers ML, Paulson J, Hoskins AA. Rapid isolation and single-molecule analysis of ribonucleoproteins from cell lysate by SNAP-SiMPull. Rna (New York, N.Y.). 21: 1031-41. PMID 25805862 DOI: 10.1261/rna.047845.114  0.307
2014 Larson J, Kirk M, Drier EA, O'Brien W, MacKay JF, Friedman LJ, Hoskins AA. Design and construction of a multiwavelength, micromirror total internal reflectance fluorescence microscope. Nature Protocols. 9: 2317-28. PMID 25188633 DOI: 10.1038/nprot.2014.155  0.721
2014 Wang TY, Friedman LJ, Gelles J, Min W, Hoskins AA, Cornish VW. The covalent trimethoprim chemical tag facilitates single molecule imaging with organic fluorophores. Biophysical Journal. 106: 272-8. PMID 24411259 DOI: 10.1016/J.Bpj.2013.11.4488  0.523
2014 Carrocci TJ, Hoskins AA. Imaging of RNAs in live cells with spectrally diverse small molecule fluorophores. The Analyst. 139: 44-7. PMID 24187681 DOI: 10.1039/c3an01550e  0.785
2014 Larson JD, Rodgers ML, Hoskins AA. Visualizing cellular machines with colocalization single molecule microscopy. Chemical Society Reviews. 43: 1189-200. PMID 23970346 DOI: 10.1039/c3cs60208g  0.758
2013 Shcherbakova I, Hoskins AA, Friedman LJ, Serebrov V, Corrêa IR, Xu MQ, Gelles J, Moore MJ. Alternative spliceosome assembly pathways revealed by single-molecule fluorescence microscopy. Cell Reports. 5: 151-65. PMID 24075986 DOI: 10.1016/J.Celrep.2013.08.026  0.723
2013 Crawford DJ, Hoskins AA, Friedman LJ, Gelles J, Moore MJ. Single-molecule colocalization FRET evidence that spliceosome activation precedes stable approach of 5' splice site and branch site. Proceedings of the National Academy of Sciences of the United States of America. 110: 6783-8. PMID 23569281 DOI: 10.1073/Pnas.1219305110  0.732
2012 Hoskins AA, Moore MJ. The spliceosome: a flexible, reversible macromolecular machine. Trends in Biochemical Sciences. 37: 179-88. PMID 22480731 DOI: 10.1016/J.Tibs.2012.02.009  0.582
2011 Hoskins AA, Gelles J, Moore MJ. New insights into the spliceosome by single molecule fluorescence microscopy. Current Opinion in Chemical Biology. 15: 864-70. PMID 22057211 DOI: 10.1016/J.Cbpa.2011.10.010  0.764
2011 Hoskins AA, Friedman LJ, Gallagher SS, Crawford DJ, Anderson EG, Wombacher R, Ramirez N, Cornish VW, Gelles J, Moore MJ. Ordered and dynamic assembly of single spliceosomes. Science (New York, N.Y.). 331: 1289-95. PMID 21393538 DOI: 10.1126/Science.1198830  0.73
2008 Morar M, Hoskins AA, Stubbe J, Ealick SE. Formylglycinamide ribonucleotide amidotransferase from Thermotoga maritima: structural insights into complex formation. Biochemistry. 47: 7816-30. PMID 18597481 DOI: 10.1021/Bi800329P  0.467
2008 Crawford DJ, Hoskins AA, Friedman LJ, Gelles J, Moore MJ. Visualizing the splicing of single pre-mRNA molecules in whole cell extract. Rna (New York, N.Y.). 14: 170-9. PMID 18025254 DOI: 10.1261/Rna.794808  0.726
2007 Hoskins AA, Morar M, Kappock TJ, Mathews II, Zaugg JB, Barder TE, Peng P, Okamoto A, Ealick SE, Stubbe J. N5-CAIR mutase: role of a CO2 binding site and substrate movement in catalysis. Biochemistry. 46: 2842-55. PMID 17298082 DOI: 10.1021/Bi602436G  0.428
2006 Morar M, Anand R, Hoskins AA, Stubbe J, Ealick SE. Complexed structures of formylglycinamide ribonucleotide amidotransferase from Thermotoga maritima describe a novel ATP binding protein superfamily. Biochemistry. 45: 14880-95. PMID 17154526 DOI: 10.1021/Bi061591U  0.521
2004 Anand R, Hoskins AA, Bennett EM, Sintchak MD, Stubbe J, Ealick SE. A model for the Bacillus subtilis formylglycinamide ribonucleotide amidotransferase multiprotein complex. Biochemistry. 43: 10343-52. PMID 15301532 DOI: 10.1021/Bi0491292  0.478
2004 Anand R, Hoskins AA, Stubbe J, Ealick SE. Domain organization of Salmonella typhimurium formylglycinamide ribonucleotide amidotransferase revealed by X-ray crystallography. Biochemistry. 43: 10328-42. PMID 15301531 DOI: 10.1021/Bi0491301  0.461
2004 Hoskins AA, Anand R, Ealick SE, Stubbe J. The formylglycinamide ribonucleotide amidotransferase complex from Bacillus subtilis: metabolite-mediated complex formation. Biochemistry. 43: 10314-27. PMID 15301530 DOI: 10.1021/Bi049127H  0.482
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