| Year |
Citation |
Score |
| 2024 |
Stevens-Sostre WA, Flores-Aldama L, Bustos D, Li J, Morais-Cabral JH, Delemotte L, Robertson GA. An intracellular hydrophobic nexus critical for hERG1 channel slow deactivation. Biophysical Journal. PMID 38219015 DOI: 10.1016/j.bpj.2024.01.010 |
0.413 |
|
| 2023 |
Jameson MB, Ríos-Pérez EB, Liu F, Eichel CA, Robertson GA. Pairwise biosynthesis of ion channels stabilizes excitability and mitigates arrhythmias. Proceedings of the National Academy of Sciences of the United States of America. 120: e2305295120. PMID 37816059 DOI: 10.1073/pnas.2305295120 |
0.832 |
|
| 2021 |
Harley CA, Bernardo-Seisdedos G, Stevens-Sostre WA, Jones DK, Azevedo MM, Sampaio P, Lorga-Gomes M, Trudeau MC, Millet O, Robertson GA, Morais-Cabral JH. Conformation-sensitive antibody reveals an altered cytosolic PAS/CNBh assembly during hERG channel gating. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34716268 DOI: 10.1073/pnas.2108796118 |
0.791 |
|
| 2021 |
Ríos-Pérez EB, Liu F, Stevens-Sostre WA, Eichel CA, Silignavong J, Robertson GA. A stable cell line inducibly expressing hERG1a/1b heteromeric channels. Journal of Pharmacological and Toxicological Methods. 107081. PMID 34058320 DOI: 10.1016/j.vascn.2021.107081 |
0.779 |
|
| 2021 |
Feng L, Zhang J, Lee C, Kim G, Liu F, Petersen AJ, Lim E, Anderson CL, Orland KM, Robertson GA, Eckhardt LL, January CT, Kamp TJ. Long QT Syndrome 2 PAS Domain Variant Induces hERG1a/1b Subunit Imbalance in Patient-specific iPSC-cardiomyocytes. Circulation. Arrhythmia and Electrophysiology. PMID 33729832 DOI: 10.1161/CIRCEP.120.009343 |
0.319 |
|
| 2019 |
Eichel CA, Rios-Pérez EB, Liu F, Jameson MB, Jones DK, Knickelbine JJ, Robertson GA. A microtranslatome coordinately regulates sodium and potassium currents in the human heart. Elife. 8. PMID 31670657 DOI: 10.7554/Elife.52654 |
0.814 |
|
| 2019 |
Robertson GA, Morais-Cabral JH. hERG Function in Light of Structure. Biophysical Journal. PMID 31669064 DOI: 10.1016/J.Bpj.2019.10.010 |
0.381 |
|
| 2019 |
Eichel CA, Ríos-Pérez EB, Liu F, Jameson MB, Jones DK, Knickelbine JJ, Robertson GA. Author response: A microtranslatome coordinately regulates sodium and potassium currents in the human heart Elife. DOI: 10.7554/Elife.52654.052 |
0.505 |
|
| 2018 |
Castro-Rodrigues AF, Zhao Y, Fonseca F, Gabant G, Cadene M, Robertson GA, Morais-Cabral JH. The Interaction between the Drosophila EAG Potassium Channel and the Protein Kinase CaMKII Involves an Extensive Interface at the Active Site of the Kinase. Journal of Molecular Biology. PMID 30381148 DOI: 10.1016/J.Jmb.2018.10.015 |
0.479 |
|
| 2018 |
Jones DK, Johnson A, Roti Roti EC, Liu F, Uelmen R, Ayers RA, Baczko I, Tester DJ, Ackerman MJ, Trudeau MC, Robertson GA. Localization and functional consequences of a direct interaction between TRIOBP-1 and hERG/KCNH2 proteins in the heart. Journal of Cell Science. PMID 29507111 DOI: 10.1242/Jcs.206730 |
0.738 |
|
| 2018 |
Eichel CA, Rios-Perez E, Liu F, Jones DK, Robertson GA. Association of HERG and SCN5A Transcripts Regulates Ion Channel Expression and Function in Stem Cell Derived Cardiomyocytes Biophysical Journal. 114: 378a-379a. DOI: 10.1016/J.Bpj.2017.11.2095 |
0.582 |
|
| 2018 |
Jones DK, Harley C, Amolo A, Morais-Cabral J, Robertson GA. The hERG PAS Domain Facilitates Gating Charge Deactivation at Physiological Temperature Biophysical Journal. 114: 374a. DOI: 10.1016/J.Bpj.2017.11.2072 |
0.454 |
|
| 2017 |
Zhao Y, Goldschen-Ohm MP, Morais-Cabral JH, Chanda B, Robertson GA. The intrinsically liganded cyclic nucleotide-binding homology domain promotes KCNH channel activation. The Journal of General Physiology. PMID 28122815 DOI: 10.1085/Jgp.201611701 |
0.511 |
|
| 2016 |
Harley CA, Starek G, Jones DK, Fernandes AS, Robertson GA, Morais-Cabral JH. Enhancement of hERG channel activity by scFv antibody fragments targeted to the PAS domain. Proceedings of the National Academy of Sciences of the United States of America. PMID 27516548 DOI: 10.1073/Pnas.1601116113 |
0.648 |
|
| 2016 |
Liu F, Jones DK, de Lange WJ, Robertson GA. Cotranslational association of mRNA encoding subunits of heteromeric ion channels. Proceedings of the National Academy of Sciences of the United States of America. PMID 27078096 DOI: 10.1073/Pnas.1521577113 |
0.624 |
|
| 2016 |
Jones DK, Liu F, Dombrowski N, Joshi S, Robertson GA. Dominant Negative Consequences of a hERG 1b-Specific Mutation Associated with Intrauterine Fetal Death. Progress in Biophysics and Molecular Biology. PMID 26772437 DOI: 10.1016/J.Pbiomolbio.2016.01.002 |
0.682 |
|
| 2016 |
Starek G, Harley CA, Jones DK, Robertson GA, Morais-Cabral JH. Targeted Enhancement of hERG K+ Channel Activity with scFv Antibody Fragments Biophysical Journal. 110: 344a. DOI: 10.1016/J.Bpj.2015.11.1851 |
0.665 |
|
| 2016 |
Zhao Y, Morais-Cabral JH, Fernandes AS, Robertson GA. An Intrinsic Ligand Mediates N- and C-Terminal Interactions with the KCNH Gating Machinery Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.1850 |
0.448 |
|
| 2016 |
Johnson AA, Jones D, Roti Roti EC, Robertson G, Trudeau M. The F-Actin Binding Protein TRIOBP-1 Regulates hERG K+ Channels Biophysical Journal. 110: 186a. DOI: 10.1016/J.Bpj.2015.11.1036 |
0.808 |
|
| 2015 |
Morais-Cabral JH, Robertson GA. The enigmatic cytoplasmic regions of KCNH channels. Journal of Molecular Biology. 427: 67-76. PMID 25158096 DOI: 10.1016/J.Jmb.2014.08.008 |
0.513 |
|
| 2015 |
Kuo JS, Pointer KB, Clark PA, Robertson G. 139 Human Ether-a-Go-Go-Related-1 Gene (hERG) K+ Channel as a Prognostic Marker and Therapeutic Target for Glioblastoma Neurosurgery. 62: 210-211. DOI: 10.1227/01.Neu.0000467101.37429.Ad |
0.439 |
|
| 2015 |
Pointer KB, Liu F, Jones DK, Clark PA, Robertson GA, Kuo JS. Abstract B15: Human ether-a-go-go-related-1 gene (hERG) K+ channel as a prognostic marker and therapeutic target for glioblastoma Brain. 75. DOI: 10.1158/1538-7445.Brain15-B15 |
0.545 |
|
| 2015 |
Jones D, Liu F, Anson B, Fiene S, Trudeau M, Robertson G. Loss of hERG 1b is arrhythmogenic in human cardiomyocytes Journal of Pharmacological and Toxicological Methods. 75: 166-167. DOI: 10.1016/J.Vascn.2015.08.031 |
0.759 |
|
| 2015 |
Zhao Y, Peters CH, Ruben PC, Robertson GA. Homologous Domains Mediate Distinct Gating Functions in EAG vs. Cyclic-Nucleotide Gated Channels Biophysical Journal. 108: 276a-277a. DOI: 10.1016/J.Bpj.2014.11.1515 |
0.734 |
|
| 2014 |
Jones DK, Liu F, Vaidyanathan R, Eckhardt LL, Trudeau MC, Robertson GA. hERG 1b is critical for human cardiac repolarization. Proceedings of the National Academy of Sciences of the United States of America. 111: 18073-7. PMID 25453103 DOI: 10.1073/Pnas.1414945111 |
0.81 |
|
| 2014 |
Zhao Y, Tran P, Morais Cabral J, Robertson GA. A Salt Bridge Links CNBhD Conformation to the Gating Machinery in EAG Potassium Channels Biophysical Journal. 106: 139a-140a. DOI: 10.1016/J.Bpj.2013.11.813 |
0.528 |
|
| 2013 |
Robertson GA. High-resolution scanning patch clamp: life on the nanosurface. Circulation Research. 112: 1088-90. PMID 23580769 DOI: 10.1161/Circresaha.113.301212 |
0.418 |
|
| 2013 |
Zhao YX, Tran PN, Skipina TM, Marques-Carvalho MJ, Morais-Cabral JH, Robertson GA. Functional Properties of the “Unliganded” CNBhD in EAG K Channels Biophysical Journal. 104: 356a. DOI: 10.1016/J.Bpj.2012.11.1977 |
0.474 |
|
| 2012 |
Robertson GA. hERG Subunit-Specific Contributions to Gating and Disease Biophysical Journal. 102: 212a. DOI: 10.1016/J.Bpj.2011.11.1157 |
0.57 |
|
| 2011 |
Trudeau MC, Leung LM, Roti ER, Robertson GA. hERG1a N-terminal eag domain-containing polypeptides regulate homomeric hERG1b and heteromeric hERG1a/hERG1b channels: a possible mechanism for long QT syndrome. The Journal of General Physiology. 138: 581-92. PMID 22124116 DOI: 10.1085/Jgp.201110683 |
0.802 |
|
| 2011 |
Abi-Gerges N, Holkham H, Jones EM, Pollard CE, Valentin JP, Robertson GA. hERG subunit composition determines differential drug sensitivity. British Journal of Pharmacology. 164: 419-32. PMID 21449979 DOI: 10.1111/J.1476-5381.2011.01378.X |
0.459 |
|
| 2010 |
Es-Salah-Lamoureux Z, Fougere R, Xiong PY, Robertson GA, Fedida D. Fluorescence-tracking of activation gating in human ERG channels reveals rapid S4 movement and slow pore opening. Plos One. 5: e10876. PMID 20526358 DOI: 10.1371/Journal.Pone.0010876 |
0.539 |
|
| 2010 |
Fergestad T, Sale H, Bostwick B, Schaffer A, Ho L, Robertson GA, Ganetzky B. A Drosophila behavioral mutant, down and out (dao), is defective in an essential regulator of Erg potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 107: 5617-21. PMID 20212103 DOI: 10.1073/Pnas.1001494107 |
0.706 |
|
| 2010 |
Holkham HO, Robertson GA, Pollard CE, Valentin J, Abi-Gerges N. hERG1a/1B heteromeric and hERG1a homomeric channels exhibit different pharmacological sensitivities Journal of Pharmacological and Toxicological Methods. 62: e1. DOI: 10.1016/J.Vascn.2010.11.006 |
0.518 |
|
| 2010 |
Trudeau M, Roti ER, Robertson G. A New Mechanism for Long QT Syndrome: Polypeptides Encoded by hERG1a Non-Sense Mutations Regulate hERG1a/1b Channels Biophysical Journal. 98: 119. DOI: 10.1016/J.Bpj.2009.12.651 |
0.538 |
|
| 2010 |
Abi-Gerges N, Holkham H, Pollard C, Valentin J, Robertson GA. hERG Heteromeric 1A/1B and Homomeric 1A Channels Exhibit Differential Pharmacological Sensitivities Biophysical Journal. 98: 119a. DOI: 10.1016/J.Bpj.2009.12.650 |
0.424 |
|
| 2010 |
Robertson GA. Voltage-Gated Potassium Channels (Kv10-Kv12) Encyclopedia of Neuroscience. 443-451. DOI: 10.1016/B978-008045046-9.01631-4 |
0.429 |
|
| 2009 |
Robertson GA. Endocytic control of ion channel density as a target for cardiovascular disease. The Journal of Clinical Investigation. 119: 2531-4. PMID 19726880 DOI: 10.1172/Jci40427 |
0.539 |
|
| 2009 |
Wynia-Smith S, Robertson G. Mapping the hERG Channel Activation Gate Using SCAM Biophysical Journal. 96: 189a. DOI: 10.1016/J.Bpj.2008.12.886 |
0.551 |
|
| 2009 |
Roti ECR, Robertson GA. N-Terminal LQT2 Nonsense Mutations Cause a Dominant-Negative Destabilization of WT hERG Subunits Biophysical Journal. 96: 1-5. DOI: 10.1016/J.Bpj.2008.12.451 |
0.386 |
|
| 2008 |
Wynia-Smith SL, Gillian-Daniel AL, Satyshur KA, Robertson GA. hERG gating microdomains defined by S6 mutagenesis and molecular modeling. The Journal of General Physiology. 132: 507-20. PMID 18955593 DOI: 10.1085/Jgp.200810083 |
0.504 |
|
| 2008 |
Sale H, Wang J, O'Hara TJ, Tester DJ, Phartiyal P, He JQ, Rudy Y, Ackerman MJ, Robertson GA. Physiological properties of hERG 1a/1b heteromeric currents and a hERG 1b-specific mutation associated with Long-QT syndrome. Circulation Research. 103: e81-95. PMID 18776039 DOI: 10.1161/Circresaha.108.185249 |
0.821 |
|
| 2008 |
Sridhar A, Nishijima Y, Terentyev D, Terentyeva R, Uelmen R, Kukielka M, Bonilla IM, Robertson GA, Györke S, Billman GE, Carnes CA. Repolarization abnormalities and afterdepolarizations in a canine model of sudden cardiac death. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R1463-72. PMID 18768760 DOI: 10.1152/Ajpregu.90583.2008 |
0.758 |
|
| 2008 |
Phartiyal P, Sale H, Jones EM, Robertson GA. Endoplasmic reticulum retention and rescue by heteromeric assembly regulate human ERG 1a/1b surface channel composition. The Journal of Biological Chemistry. 283: 3702-7. PMID 18048364 DOI: 10.1074/Jbc.M708999200 |
0.82 |
|
| 2007 |
Phartiyal P, Jones EM, Robertson GA. Heteromeric assembly of human ether-Ã -go-go-related gene (hERG) 1a/1b channels occurs cotranslationally via N-terminal interactions. The Journal of Biological Chemistry. 282: 9874-82. PMID 17272276 DOI: 10.1074/Jbc.M610875200 |
0.802 |
|
| 2006 |
Robertson GA, January CT. HERG trafficking and pharmacological rescue of LQTS-2 mutant channels. Handbook of Experimental Pharmacology. 349-55. PMID 16610352 DOI: 10.1007/3-540-29715-4-14 |
0.422 |
|
| 2006 |
Rajamani S, Anderson CL, Valdivia CR, Eckhardt LL, Foell JD, Robertson GA, Kamp TJ, Makielski JC, Anson BD, January CT. Specific serine proteases selectively damage KCNH2 (hERG1) potassium channels and I(Kr). American Journal of Physiology. Heart and Circulatory Physiology. 290: H1278-88. PMID 16227340 DOI: 10.1152/Ajpheart.00777.2005 |
0.733 |
|
| 2005 |
Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stühmer W, Wang X. International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pharmacological Reviews. 57: 473-508. PMID 16382104 DOI: 10.1124/pr.57.4.10 |
0.403 |
|
| 2005 |
Robertson GA, Jones EM, Wang J. Gating and assembly of heteromeric hERG1a/1b channels underlying I(Kr) in the heart. Novartis Foundation Symposium. 266: 4-15; discussion 15-. PMID 16050259 DOI: 10.1002/047002142X.Ch2 |
0.689 |
|
| 2004 |
Jones EM, Roti Roti EC, Wang J, Delfosse SA, Robertson GA. Cardiac IKr channels minimally comprise hERG 1a and 1b subunits. The Journal of Biological Chemistry. 279: 44690-4. PMID 15304481 DOI: 10.1074/Jbc.M408344200 |
0.831 |
|
| 2003 |
Gutman GA, Chandy KG, Adelman JP, Aiyar J, Bayliss DA, Clapham DE, Covarriubias M, Desir GV, Furuichi K, Ganetzky B, Garcia ML, Grissmer S, Jan LY, Karschin A, Kim D, ... ... Robertson GA, et al. International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels. Pharmacological Reviews. 55: 583-6. PMID 14657415 DOI: 10.1124/Pr.55.4.9 |
0.709 |
|
| 2002 |
Roti EC, Myers CD, Ayers RA, Boatman DE, Delfosse SA, Chan EK, Ackerman MJ, January CT, Robertson GA. Interaction with GM130 during HERG ion channel trafficking. Disruption by type 2 congenital long QT syndrome mutations. Human Ether-Ã -go-go-Related Gene. The Journal of Biological Chemistry. 277: 47779-85. PMID 12270925 DOI: 10.1074/Jbc.M206638200 |
0.524 |
|
| 2002 |
Pardo-López L, GarcÃa-Valdés J, Gurrola GB, Robertson GA, Possani LD. Mapping the receptor site for ergtoxin, a specific blocker of ERG channels. Febs Letters. 510: 45-9. PMID 11755529 DOI: 10.1016/S0014-5793(01)03218-5 |
0.536 |
|
| 2000 |
Wang J, Myers CD, Robertson GA. Dynamic control of deactivation gating by a soluble amino-terminal domain in HERG K(+) channels. The Journal of General Physiology. 115: 749-58. PMID 10828248 DOI: 10.1085/Jgp.115.6.749 |
0.662 |
|
| 2000 |
Emmi A, Wenzel HJ, Schwartzkroin PA, Taglialatela M, Castaldo P, Bianchi L, Nerbonne J, Robertson GA, Janigro D. Do glia have heart? Expression and functional role for ether-a-go-go currents in hippocampal astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3915-25. PMID 10804231 DOI: 10.1523/Jneurosci.20-10-03915.2000 |
0.443 |
|
| 2000 |
Robertson GA. LQT2 : amplitude reduction and loss of selectivity in the tail that wags the HERG channel. Circulation Research. 86: 492-3. PMID 10720408 DOI: 10.1161/01.Res.86.5.492 |
0.559 |
|
| 1999 |
Ganetzky B, Robertson GA, Wilson GF, Trudeau MC, Titus SA. The eag family of K+ channels in Drosophila and mammals. Annals of the New York Academy of Sciences. 868: 356-69. PMID 10414305 DOI: 10.1111/J.1749-6632.1999.Tb11297.X |
0.853 |
|
| 1999 |
Furutani M, Trudeau MC, Hagiwara N, Seki A, Gong Q, Zhou Z, Imamura S, Nagashima H, Kasanuki H, Takao A, Momma K, January CT, Robertson GA, Matsuoka R. Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel. Circulation. 99: 2290-4. PMID 10226095 DOI: 10.1161/01.Cir.99.17.2290 |
0.781 |
|
| 1999 |
Trudeau MC, Titus SA, Branchaw JL, Ganetzky B, Robertson GA. Functional analysis of a mouse brain Elk-type K+ channel. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2906-18. PMID 10191308 DOI: 10.1523/Jneurosci.19-08-02906.1999 |
0.834 |
|
| 1998 |
Wang J, Trudeau MC, Zappia AM, Robertson GA. Regulation of deactivation by an amino terminal domain in human ether-Ã -go-go-related gene potassium channels. The Journal of General Physiology. 112: 637-47. PMID 9806971 DOI: 10.1085/Jgp.112.5.637 |
0.8 |
|
| 1998 |
Herzberg IM, Trudeau MC, Robertson GA. Transfer of rapid inactivation and sensitivity to the class III antiarrhythmic drug E-4031 from HERG to M-eag channels. The Journal of Physiology. 511: 3-14. PMID 9679158 DOI: 10.1111/J.1469-7793.1998.003Bi.X |
0.741 |
|
| 1998 |
Zhou Z, Gong Q, Ye B, Fan Z, Makielski JC, Robertson GA, January CT. Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature. Biophysical Journal. 74: 230-41. PMID 9449325 DOI: 10.1016/S0006-3495(98)77782-3 |
0.507 |
|
| 1997 |
London B, Trudeau MC, Newton KP, Beyer AK, Copeland NG, Gilbert DJ, Jenkins NA, Satler CA, Robertson GA. Two isoforms of the mouse ether-a-go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current. Circulation Research. 81: 870-8. PMID 9351462 DOI: 10.1161/01.Res.81.5.870 |
0.773 |
|
| 1996 |
Trudeau MC, Warmke JW, Ganetzky B, Robertson GA. HERG sequence correction. Science (New York, N.Y.). 272: 1087c. PMID 17792628 DOI: 10.1126/Science.272.5265.1087C |
0.758 |
|
| 1996 |
Robertson GA, Warmke JM, Ganetzky B. Potassium currents expressed from Drosophila and mouse eag cDNAs in Xenopus oocytes. Neuropharmacology. 35: 841-50. PMID 8938715 DOI: 10.1016/0028-3908(96)00113-X |
0.846 |
|
| 1996 |
Trudeau MC, Warmke JW, Ganetzky B, Robertson GA. HERG sequence correction. Science (New York, N.Y.). 272: 1087. PMID 8638148 |
0.735 |
|
| 1995 |
Ganetzky B, Warmke JW, Robertson G, Pallanck L. New potassium channel gene families in flies and mammals: from mutants to molecules. Society of General Physiologists Series. 50: 29-39. PMID 7676322 |
0.805 |
|
| 1995 |
Trudeau MC, Warmke JW, Ganetzky B, Robertson GA. HERG, a human inward rectifier in the voltage-gated potassium channel family. Science (New York, N.Y.). 269: 92-5. PMID 7604285 DOI: 10.1126/Science.7604285 |
0.837 |
|
| 1995 |
Ganetzky B, Warmke JW, Robertson G, Pallanck L. New potassium channel gene families in flies and mammals: From mutants to molecules Journal of General Physiology. 29-39. |
0.362 |
|
| 1991 |
Atkinson NS, Robertson GA, Ganetzky B. A component of calcium-activated potassium channels encoded by the Drosophila slo locus. Science (New York, N.Y.). 253: 551-5. PMID 1857984 DOI: 10.1126/Science.1857984 |
0.769 |
|
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