| Year |
Citation |
Score |
| 2023 |
Oyaghire SN, Quijano E, Perera JDR, Mandl HK, Saltzman WM, Bahal R, Glazer PM. DNA recognition and induced genome modification by a hydroxymethyl-γ tail-clamp peptide nucleic acid. Cell Reports. Physical Science. 4. PMID 37920723 DOI: 10.1016/j.xcrp.2023.101635 |
0.572 |
|
| 2022 |
Putman R, Ricciardi AS, Carufe KEW, Quijano E, Bahal R, Glazer PM, Saltzman WM. Nanoparticle-mediated genome editing in single-cell embryos via peptide nucleic acids. Bioengineering & Translational Medicine. 8: e10458. PMID 37206203 DOI: 10.1002/btm2.10458 |
0.537 |
|
| 2022 |
Piotrowski-Daspit AS, Barone C, Lin CY, Deng Y, Wu D, Binns TC, Xu E, Ricciardi AS, Putman R, Garrison A, Nguyen R, Gupta A, Fan R, Glazer PM, Saltzman WM, et al. In vivo correction of cystic fibrosis mediated by PNA nanoparticles. Science Advances. 8: eabo0522. PMID 36197984 DOI: 10.1126/sciadv.abo0522 |
0.689 |
|
| 2022 |
Singh C, Bindra RS, Glazer PM, Vasquez JC, Pashankar F. Metastatic and multiply relapsed SDH-deficient GIST and paraganglioma displays clinical response to combined poly ADP-ribose polymerase inhibition and temozolomide. Pediatric Blood & Cancer. e30020. PMID 36151992 DOI: 10.1002/pbc.30020 |
0.48 |
|
| 2021 |
Eder JP, Doroshow DB, Do KT, Keedy VL, Sklar JS, Glazer P, Bindra R, Shapiro GI. Clinical Efficacy of Olaparib in Mutant Mesenchymal Sarcomas. Jco Precision Oncology. 5: 466-472. PMID 34994649 DOI: 10.1200/PO.20.00247 |
0.526 |
|
| 2021 |
Gayle S, Aiello R, Leelatian N, Beckta JM, Bechtold J, Bourassa P, Csengery J, Maguire RJ, Marshall D, Sundaram RK, Van Doorn J, Jones K, Moore H, Lopresti-Morrow L, Paradis T, ... ... Glazer PM, et al. Correction to 'Tumor-selective, antigen-independent delivery of a pH sensitive peptide-topoisomerase inhibitor conjugate suppresses tumor growth without systemic toxicity'. Nar Cancer. 3: zcab047. PMID 34888524 DOI: 10.1093/narcan/zcab047 |
0.504 |
|
| 2021 |
Dow J, Krysztofiak A, Liu Y, Colon-Rios DA, Rogers FA, Glazer PM. Vulnerability of IDH1-Mutant Cancers to Histone Deacetylase Inhibition via Orthogonal Suppression of DNA Repair. Molecular Cancer Research : McR. PMID 34535560 DOI: 10.1158/1541-7786.MCR-21-0456 |
0.33 |
|
| 2021 |
Gayle S, Aiello R, Leelatian N, Beckta JM, Bechtold J, Bourassa P, Csengery J, Maguire RJ, Marshall D, Sundaram RK, Van Doorn J, Jones K, Moore H, Lopresti-Morrow L, Paradis T, ... ... Glazer PM, et al. Tumor-selective, antigen-independent delivery of a pH sensitive peptide-topoisomerase inhibitor conjugate suppresses tumor growth without systemic toxicity. Nar Cancer. 3: zcab021. PMID 34316708 DOI: 10.1093/narcan/zcab021 |
0.564 |
|
| 2021 |
Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, ... ... Glazer PM, et al. The NIH Somatic Cell Genome Editing program. Nature. 592: 195-204. PMID 33828315 DOI: 10.1038/s41586-021-03191-1 |
0.441 |
|
| 2021 |
Ullrich SJ, Freedman-Weiss M, Ahle S, Mandl HK, Piotrowski-Daspit AS, Roberts K, Yung N, Maassel N, Bauer-Pisani T, Ricciardi AS, Egan ME, Glazer PM, Saltzman WM, Stitelman DH. Nanoparticles for Delivery of Agents to Fetal Lungs. Acta Biomaterialia. PMID 33484911 DOI: 10.1016/j.actbio.2021.01.024 |
0.643 |
|
| 2020 |
Liu W, Deacon J, Yan H, Sun B, Liu Y, Hegan D, Li Q, Coman D, Parent M, Hyder F, Roberts K, Nath R, Tillement O, Engelman D, Glazer P. Tumor-targeted pH-low insertion peptide delivery of theranostic gadolinium nanoparticles for image-guided nanoparticle-enhanced radiation therapy. Translational Oncology. 13: 100839. PMID 32763504 DOI: 10.1016/J.Tranon.2020.100839 |
0.35 |
|
| 2020 |
Sulkowski PL, Oeck S, Dow J, Economos NG, Mirfakhraie L, Liu Y, Noronha K, Bao X, Li J, Shuch BM, King MC, Bindra RS, Glazer PM. Oncometabolites suppress DNA repair by disrupting local chromatin signalling. Nature. PMID 32494005 DOI: 10.1038/S41586-020-2363-0 |
0.664 |
|
| 2020 |
Kaplan AR, Glazer PM. Pharmacological methods to transcriptionally modulate double-strand break DNA repair. International Review of Cell and Molecular Biology. 354: 187-213. PMID 32475473 DOI: 10.1016/Bs.Ircmb.2019.11.003 |
0.431 |
|
| 2020 |
Kaplan AR, Pham H, Liu Y, Oyaghire S, Bahal R, Engelman DM, Glazer PM. Ku80-targeted pH-sensitive peptide-PNA conjugates are tumor selective and sensitize cancer cells to ionizing radiation. Molecular Cancer Research : McR. PMID 32098827 DOI: 10.1158/1541-7786.Mcr-19-0661 |
0.397 |
|
| 2020 |
Oyaghire SN, Quijano E, Piotrowski-Daspit AS, Saltzman WM, Glazer PM. Poly(Lactic-co-Glycolic Acid) Nanoparticle Delivery of Peptide Nucleic Acids In Vivo. Methods in Molecular Biology (Clifton, N.J.). 2105: 261-281. PMID 32088877 DOI: 10.1007/978-1-0716-0243-0_17 |
0.574 |
|
| 2020 |
Economos NG, Oyaghire S, Quijano E, Ricciardi AS, Saltzman WM, Glazer PM. Peptide Nucleic Acids and Gene Editing: Perspectives on Structure and Repair. Molecules (Basel, Switzerland). 25. PMID 32046275 DOI: 10.3390/Molecules25030735 |
0.584 |
|
| 2020 |
Gayle S, Aiello R, Bechtold J, Bourassa P, Csengery J, Deshpande K, Jones K, Lopresti-Morrow L, Maguire R, Marshall D, Moore H, Paradis T, Tylaska L, Zhang Q, Volkmann R, ... ... Glazer PM, et al. Abstract 6242: Development of alphalex™-toxin low pH targeting conjugates for the treatment of solid tumors Cancer Research. 80: 6242-6242. DOI: 10.1158/1538-7445.Am2020-6242 |
0.599 |
|
| 2019 |
Svoronos AA, Bahal R, Pereira MC, Barrera FN, Deacon JC, Bosenberg M, DiMaio D, Glazer PM, Engelman DM. Tumor-Targeted, Cytoplasmic Delivery of Large, Polar Molecules using a pH-Low Insertion Peptide. Molecular Pharmaceutics. PMID 31855437 DOI: 10.1021/Acs.Molpharmaceut.9B00883 |
0.335 |
|
| 2019 |
Mandl HK, Quijano E, Suh HW, Sparago E, Oeck S, Grun M, Glazer PM, Saltzman WM. Optimizing biodegradable nanoparticle size for tissue-specific delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 314: 92-101. PMID 31654688 DOI: 10.1016/J.Jconrel.2019.09.020 |
0.476 |
|
| 2019 |
Kaplan AR, Glazer PM. Impact of hypoxia on DNA repair and genome integrity. Mutagenesis. PMID 31282537 DOI: 10.1093/Mutage/Gez019 |
0.424 |
|
| 2019 |
Kaplan AR, Gueble SE, Liu Y, Oeck S, Kim H, Yun Z, Glazer PM. Cediranib suppresses homology-directed DNA repair through down-regulation of BRCA1/2 and RAD51. Science Translational Medicine. 11. PMID 31092693 DOI: 10.1126/Scitranslmed.Aav4508 |
0.472 |
|
| 2019 |
Turchick A, Liu Y, Zhao W, Cohen I, Glazer PM. Synthetic lethality of a cell-penetrating anti-RAD51 antibody in PTEN-deficient melanoma and glioma cells. Oncotarget. 10: 1272-1283. PMID 30863489 DOI: 10.18632/Oncotarget.26654 |
0.457 |
|
| 2019 |
Oeck S, Malewicz NM, Krysztofiak A, Turchick A, Jendrossek V, Glazer PM. High-throughput Evaluation of Protein Migration and Localization after Laser Micro-Irradiation. Scientific Reports. 9: 3148. PMID 30816253 DOI: 10.1038/S41598-019-39760-8 |
0.369 |
|
| 2019 |
Bindra R, Sundaram RK, Aiello RJ, Marshall D, Bourassa P, Csengery J, Zhang Q, Robinson B, lopresti-Morrow L, Bechtold J, Tylaska L, Paradis T, Paralkar V, Hellsund P, Glazer P. Unlocking PARP inhibitor efficacy for HRD-negative cancers using the alphalex tumor targeting platform inhibitor efficacy for HRD-negative cancers using the alphalex tumor targeting platform. Journal of Clinical Oncology. 37: e14664-e14664. DOI: 10.1200/Jco.2019.37.15_Suppl.E14664 |
0.595 |
|
| 2019 |
Sulkowski PS, Oeck S, Li J, Shuch B, King MC, Bindra RS, Glazer PM. Abstract SY21-02: Oncometabolites suppress homologous recombination DNA repair by inhibition of chromatin remodeling at the DNA double-strand break Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Sy21-02 |
0.673 |
|
| 2019 |
Paralkar V, Aiello RJ, Marshall D, Csengery J, Bourassa P, Zhang Q, Robinson BS, Lopresti-Morrow L, Bechtold J, Tylaska L, Paradis T, Slaybaugh G, Visca H, Moshnikova A, Weerakkody D, ... ... Glazer P, et al. Abstract 2981: Targeting solid tumor acidic microenvironment with an alphalex PARP inhibitor Cancer Research. 79: 2981-2981. DOI: 10.1158/1538-7445.Am2019-2981 |
0.59 |
|
| 2018 |
Piotrowski-Daspit AS, Glazer PM, Saltzman WM. Debugging the genetic code: non-viral in vivo delivery of therapeutic genome editing technologies. Current Opinion in Biomedical Engineering. 7: 24-32. PMID 30984891 DOI: 10.1016/J.Cobme.2018.08.002 |
0.543 |
|
| 2018 |
Neel BG, Xu Y, Taylor P, Andrade J, Ueberheide B, Shuch B, Glazer PM, Bindra RS, Moran MF, Linehan WM. Pathological Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma. Cancer Research. PMID 30297534 DOI: 10.1158/0008-5472.Can-18-0901 |
0.572 |
|
| 2018 |
Sulkowski PL, Sundaram RK, Oeck S, Corso CD, Liu Y, Noorbakhsh S, Niger M, Boeke M, Ueno D, Kalathil AN, Bao X, Li J, Shuch B, Bindra RS, Glazer PM. Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair. Nature Genetics. PMID 30013182 DOI: 10.1038/S41588-018-0170-4 |
0.66 |
|
| 2018 |
Ricciardi AS, Bahal R, Farrelly JS, Quijano E, Bianchi AH, Luks VL, Putman R, López-Giráldez F, Coşkun S, Song E, Liu Y, Hsieh WC, Ly DH, Stitelman DH, Glazer PM, et al. In utero nanoparticle delivery for site-specific genome editing. Nature Communications. 9: 2481. PMID 29946143 DOI: 10.1038/S41467-018-04894-2 |
0.574 |
|
| 2018 |
Lu Y, Liu Y, Oeck S, Glazer PM. Hypoxia Promotes Resistance to EGFR Inhibition in NSCLC Cells via the Histone Demethylases, LSD1 and PLU-1. Molecular Cancer Research : McR. PMID 29934325 DOI: 10.1158/1541-7786.Mcr-17-0637 |
0.301 |
|
| 2018 |
Sulkowski PL, Scanlon SE, Oeck S, Glazer PM. PTEN Regulates Non-Homologous End Joining by Epigenetic Induction of NHEJ1/XLF. Molecular Cancer Research : McR. PMID 29739874 DOI: 10.1158/1541-7786.Mcr-17-0581 |
0.458 |
|
| 2018 |
Ricciardi AS, Quijano E, Putman R, Saltzman WM, Glazer PM. Peptide Nucleic Acids as a Tool for Site-Specific Gene Editing. Molecules (Basel, Switzerland). 23. PMID 29534473 DOI: 10.3390/Molecules23030632 |
0.662 |
|
| 2018 |
Kim H, Lin Q, Glazer PM, Yun Z. The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells. Breast Cancer Research : Bcr. 20: 16. PMID 29510720 DOI: 10.1186/S13058-018-0944-8 |
0.328 |
|
| 2018 |
Scanlon SE, Hegan DC, Sulkowski PL, Glazer PM. Suppression of homology-dependent DNA double-strand break repair induces PARP inhibitor sensitivity in VHL-deficient human renal cell carcinoma. Oncotarget. 9: 4647-4660. PMID 29435132 DOI: 10.18632/Oncotarget.23470 |
0.465 |
|
| 2017 |
Quijano E, Bahal R, Ricciardi A, Saltzman WM, Glazer PM.
Therapeutic Peptide Nucleic Acids: Principles, Limitations, and Opportunities
. The Yale Journal of Biology and Medicine. 90: 583-598. PMID 29259523 |
0.448 |
|
| 2017 |
Gupta A, Quijano E, Liu Y, Bahal R, Scanlon SE, Song E, Hsieh WC, Braddock DE, Ly DH, Saltzman WM, Glazer PM. Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy. Molecular Therapy. Nucleic Acids. 9: 111-119. PMID 29246289 DOI: 10.1016/J.Omtn.2017.09.001 |
0.497 |
|
| 2017 |
Turchick A, Hegan DC, Jensen RB, Glazer PM. A cell-penetrating antibody inhibits human RAD51 via direct binding. Nucleic Acids Research. PMID 29036688 DOI: 10.1093/Nar/Gkx871 |
0.448 |
|
| 2017 |
Scanlon SE, Scanlon CD, Hegan DC, Sulkowski PL, Glazer PM. Nickel induces transcriptional down-regulation of DNA repair pathways in tumorigenic and non-tumorigenic lung cells. Carcinogenesis. PMID 28472268 DOI: 10.1093/Carcin/Bgx038 |
0.439 |
|
| 2017 |
Sulkowski PL, Corso CD, Robinson ND, Scanlon SE, Purshouse KR, Bai H, Liu Y, Sundaram RK, Hegan DC, Fons NR, Breuer GA, Song Y, Mishra-Gorur K, De Feyter HM, de Graaf RA, ... ... Glazer PM, et al. 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity. Science Translational Medicine. 9. PMID 28148839 DOI: 10.1126/Scitranslmed.Aal2463 |
0.633 |
|
| 2017 |
Nemec AA, Abriola L, Merkel JS, deStanchina E, DeVeaux M, Zelterman D, Glazer PM, Sweasy JB. DNA polymerase beta germline variant confers cellular response to cisplatin therapy. Molecular Cancer Research : McR. PMID 28074003 DOI: 10.1158/1541-7786.Mcr-16-0227-T |
0.369 |
|
| 2017 |
Bindra R, Sulkowski PL, Corso CD, Glazer P, Shuch BM. Induction of a BRCAness state by oncometabolites and exploitation by PARP inhibitors. Journal of Clinical Oncology. 35: 11586-11586. DOI: 10.1200/Jco.2017.35.15_Suppl.11586 |
0.62 |
|
| 2017 |
Hollick JJ, Abriola L, Bono F, Hegan D, Klingbeil P, Liu Y, Sundaram R, Surovtseva YV, Whittaker M, Bindra RS, Glazer PM. Abstract B25: “TargetDBR”—A DNA repair drug and target discovery collaboration: Exploiting synthetic lethal, high content, and functional cellular reporter assays to accelerate DNA repair targeted drug discovery Molecular Cancer Research. 15. DOI: 10.1158/1557-3125.Dnarepair16-B25 |
0.658 |
|
| 2017 |
Sulkowski P, Corso C, Robinson N, Scanlon S, Purshouse K, Bai H, Liu Y, Sundaram R, Hegan D, Fons N, Breuer G, Song Y, Mishra K, Feyter HD, Graaf Rd, ... ... Glazer P, et al. Abstract LB-290: Oncometabolites induce a BRCAness state that can be exploited by PARP inhibitors Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-290 |
0.622 |
|
| 2017 |
Glazer PM, Turchick A. Abstract 2482: Inhibition of RAD51 with a cell penetrating antibody, 3E10 Cancer Research. 77: 2482-2482. DOI: 10.1158/1538-7445.Am2017-2482 |
0.411 |
|
| 2017 |
Scanlon SE, Sulkowski PL, Glazer PM. Abstract 2480: Suppression of homology-dependent DNA double-strand break repair induces PARP inhibitor sensitivity inVHL-deficient human renal cell carcinoma Cancer Research. 77: 2480-2480. DOI: 10.1158/1538-7445.Am2017-2480 |
0.471 |
|
| 2017 |
Corso C, Bindra R, Glazer P, Sulkowski P, Robinson N, Scanlon S, Purshouse K, Bai H, Liu Y, Sundaram R, Hegan D, Fons N, Breuer G, Song Y, Mishra-Gorur K, et al. Production of 2-Hydroxyglutarate by IDH Mutant Malignancies Induces a BRCAness State That Can be Exploited By PARP Inhibitors and Radiation International Journal of Radiation Oncology*Biology*Physics. 99: E68. DOI: 10.1016/J.Ijrobp.2017.06.754 |
0.531 |
|
| 2016 |
Bahal R, Ali McNeer N, Quijano E, Liu Y, Sulkowski P, Turchick A, Lu YC, Bhunia DC, Manna A, Greiner DL, Brehm MA, Cheng CJ, López-Giráldez F, Ricciardi A, Beloor J, ... ... Glazer PM, et al. In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery. Nature Communications. 7: 13304. PMID 27782131 DOI: 10.1038/Ncomms13304 |
0.441 |
|
| 2016 |
Glazer PM, Gupta A, Liu Y, Quijano E, Saltzman WM. Chemically Modified Gamma PNAs Targeting microRNA-210 as a Novel Anticancer Therapy With Specificity for Hypoxic Solid Tumors. International Journal of Radiation Oncology, Biology, Physics. 96: E597. PMID 27675118 DOI: 10.1016/J.Ijrobp.2016.06.2125 |
0.513 |
|
| 2016 |
Czochor JR, Sulkowski P, Glazer PM. miR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expression and Activating Error-Prone DSB Repair. Molecular Cancer Research : McR. 14: 363-73. PMID 26850462 DOI: 10.1158/1541-7786.Mcr-15-0399 |
0.331 |
|
| 2016 |
Gupta A, Bahal R, Gupta M, Glazer PM, Saltzman WM. Nanotechnology for delivery of peptide nucleic acids (PNAs). Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26776051 DOI: 10.1016/J.Jconrel.2016.01.005 |
0.494 |
|
| 2016 |
Scanlon SE, Scanlon CD, Hegan DC, Sulkowski P, Glazer PM. Abstract LB-029: Negative transcriptional and epigenetic regulation of DNA repair pathways by the heavy metals nickel and arsenic Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-029 |
0.462 |
|
| 2016 |
Turchick AL, Glazer PM. Abstract 2748: Targeting DNA repair deficient cancers with the cell-penetrating autoantibody 3E10 Cancer Research. 76: 2748-2748. DOI: 10.1158/1538-7445.Am2016-2748 |
0.438 |
|
| 2016 |
Gupta A, Liu Y, Quijano EE, Saltzman WM, Glazer PM. Abstract 1075: Chemically modified gamma PNAs targeting oncomiR-210 as a potential anticancer therapy Cancer Research. 76: 1075-1075. DOI: 10.1158/1538-7445.Am2016-1075 |
0.535 |
|
| 2016 |
Park S, Lee JW, Platt J, Sweasy J, Glazer P, Herbst R, Koo JP. E2F8 and its target genes as novel therapeutic targets for lung cancer Journal of Thoracic Oncology. 11: S29. DOI: 10.1016/J.Jtho.2015.12.048 |
0.395 |
|
| 2015 |
Weisbart RH, Chan G, Jordaan G, Noble PW, Liu Y, Glazer PM, Nishimura RN, Hansen JE. DNA-dependent targeting of cell nuclei by a lupus autoantibody. Scientific Reports. 5: 12022. PMID 26156563 DOI: 10.1038/Srep12022 |
0.411 |
|
| 2015 |
Stachelek GC, Peterson-Roth E, Liu Y, Fernandez RJ, Pike LR, Qian JM, Abriola L, Hoyer D, Hungerford W, Merkel J, Glazer PM. YU238259 is a Novel Inhibitor of Homology-dependent DNA Repair that Exhibits Synthetic Lethality and Radiosensitization in Repair-deficient Tumors. Molecular Cancer Research : McR. PMID 26116172 DOI: 10.1158/1541-7786.Mcr-15-0036 |
0.437 |
|
| 2015 |
Yun Z, Glazer PM. Tumor suppressor p53 stole the AKT in hypoxia Journal of Clinical Investigation. 125: 2264-2266. PMID 25961449 DOI: 10.1172/Jci82058 |
0.324 |
|
| 2015 |
Scanlon SE, Glazer PM. Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironment. Dna Repair. 32: 180-9. PMID 25956861 DOI: 10.1016/J.Dnarep.2015.04.030 |
0.457 |
|
| 2015 |
McNeer NA, Anandalingam K, Fields RJ, Caputo C, Kopic S, Gupta A, Quijano E, Polikoff L, Kong Y, Bahal R, Geibel JP, Glazer PM, Saltzman WM, Egan ME. Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium. Nature Communications. 6: 6952. PMID 25914116 DOI: 10.1038/Ncomms7952 |
0.82 |
|
| 2015 |
Colis LC, Hegan DC, Kaneko M, Glazer PM, Herzon SB. Mechanism of action studies of lomaiviticin a and the monomeric lomaiviticin aglycon. Selective and potent activity toward DNA double-strand break repair-deficient cell lines. Journal of the American Chemical Society. 137: 5741-7. PMID 25849366 DOI: 10.1021/Ja513117P |
0.451 |
|
| 2015 |
Gupta R, Liu AY, Glazer PM, Wajapeyee N. LKB1 preserves genome integrity by stimulating BRCA1 expression. Nucleic Acids Research. 43: 259-71. PMID 25488815 DOI: 10.1093/Nar/Gku1294 |
0.475 |
|
| 2015 |
Cheng CJ, Bahal R, Babar IA, Pincus Z, Barrera F, Liu C, Svoronos A, Braddock DT, Glazer PM, Engelman DM, Saltzman WM, Slack FJ. MicroRNA silencing for cancer therapy targeted to the tumour microenvironment. Nature. 518: 107-10. PMID 25409146 DOI: 10.1038/Nature13905 |
0.538 |
|
| 2015 |
Reza F, Glazer PM. Therapeutic genome mutagenesis using synthetic donor DNA and triplex-forming molecules. Methods in Molecular Biology (Clifton, N.J.). 1239: 39-73. PMID 25408401 DOI: 10.1007/978-1-4939-1862-1_4 |
0.449 |
|
| 2015 |
Fields RJ, Quijano E, McNeer NA, Caputo C, Bahal R, Anandalingam K, Egan ME, Glazer PM, Saltzman WM. Modified poly(lactic-co-glycolic acid) nanoparticles for enhanced cellular uptake and gene editing in the lung. Advanced Healthcare Materials. 4: 361-6. PMID 25156908 DOI: 10.1002/Adhm.201400355 |
0.775 |
|
| 2015 |
Lu Y, Chu A, Wajapeyee N, Turker MS, Glazer PM. Abstract 2887: Epigenetic silencing of the DNA repair genes, BRCA1 and MLH1, induced by hypoxic stress in a pathway dependent on the histone demethylase, LSD1 Cancer Research. 75: 2887-2887. DOI: 10.1158/1538-7445.Am2015-2887 |
0.402 |
|
| 2015 |
Aneja S, Contessa J, Husain Z, Glazer P, Hansen J, Bindra R, Yu J. mRNA Expression of TP53 Attenuates Survival of HPV+ Locally Advanced Head and Neck Cancer International Journal of Radiation Oncology*Biology*Physics. 93: E350-E351. DOI: 10.1016/J.Ijrobp.2015.07.1440 |
0.516 |
|
| 2015 |
Engelman DM, Cheng CJ, Bahal R, Babar IA, Pincus Z, Barrera FN, Liu C, Svoronos A, Braddock DT, Glazer PM, Saltzman WM, Slack FJ. pHLIP® Targeting and Delivery of PNA to Silence MicroRNA in Tumor Cells§ Biophysical Journal. 108: 552a. DOI: 10.1016/J.Bpj.2014.11.3029 |
0.544 |
|
| 2014 |
Bahal R, Quijano E, McNeer NA, Liu Y, Bhunia DC, Lopez-Giraldez F, Fields RJ, Saltzman WM, Ly DH, Glazer PM. Single-stranded γPNAs for in vivo site-specific genome editing via Watson-Crick recognition. Current Gene Therapy. 14: 331-42. PMID 25174576 DOI: 10.2174/1566523214666140825154158 |
0.841 |
|
| 2014 |
Lu Y, Wajapeyee N, Turker MS, Glazer PM. Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1. Cell Reports. 8: 501-13. PMID 25043185 DOI: 10.1016/J.Celrep.2014.06.035 |
0.395 |
|
| 2014 |
Ricciardi AS, McNeer NA, Anandalingam KK, Saltzman WM, Glazer PM. Targeted genome modification via triple helix formation. Methods in Molecular Biology (Clifton, N.J.). 1176: 89-106. PMID 25030921 DOI: 10.1007/978-1-4939-0992-6_8 |
0.801 |
|
| 2014 |
Zhang M, Xiang S, Joo HY, Wang L, Williams KA, Liu W, Hu C, Tong D, Haakenson J, Wang C, Zhang S, Pavlovicz RE, Jones A, Schmidt KH, Tang J, ... ... Glazer PM, et al. HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSα. Molecular Cell. 55: 31-46. PMID 24882211 DOI: 10.1016/J.Molcel.2014.04.028 |
0.424 |
|
| 2014 |
Colis LC, Woo CM, Hegan DC, Li Z, Glazer PM, Herzon SB. The cytotoxicity of (-)-lomaiviticin A arises from induction of double-strand breaks in DNA. Nature Chemistry. 6: 504-10. PMID 24848236 DOI: 10.1038/Nchem.1944 |
0.412 |
|
| 2014 |
Scanlon SE, Glazer PM. Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins. Molecular Cancer Research : McR. 12: 1016-28. PMID 24688021 DOI: 10.1158/1541-7786.Mcr-13-0628 |
0.396 |
|
| 2014 |
Reza F, Glazer PM. Triplex-mediated genome targeting and editing. Methods in Molecular Biology (Clifton, N.J.). 1114: 115-42. PMID 24557900 DOI: 10.1007/978-1-62703-761-7_8 |
0.407 |
|
| 2014 |
Kidane D, Chae WJ, Czochor J, Eckert KA, Glazer PM, Bothwell AL, Sweasy JB. Interplay between DNA repair and inflammation, and the link to cancer. Critical Reviews in Biochemistry and Molecular Biology. 49: 116-39. PMID 24410153 DOI: 10.3109/10409238.2013.875514 |
0.405 |
|
| 2014 |
Schleifman EB, Glazer PM. Peptide nucleic acid-mediated recombination for targeted genomic repair and modification. Methods in Molecular Biology (Clifton, N.J.). 1050: 207-22. PMID 24297362 DOI: 10.1007/978-1-62703-553-8_17 |
0.768 |
|
| 2014 |
Glazer PM. Abstract SY42-03: Novel DNA repair inhibitors for radiosensitization and cancer therapy Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Sy42-03 |
0.446 |
|
| 2014 |
Engelman DM, An M, Andreev OA, Barrera FN, Bahal R, Bosenberg MW, Cheng C, Glazer PM, Karabadzhak A, Reshetnyak YK, Saltzman WM, Slack FJ, Svoronos AA, Thevenin D. Imaging and Treating Tumors by Targeting their Acidity with Phlip, a Ph-Sensitve Insertion Peptide Biophysical Journal. 106: 231a. DOI: 10.1016/J.Bpj.2013.11.1350 |
0.524 |
|
| 2013 |
Glazer PM, Hegan DC, Lu Y, Czochor J, Scanlon SE. Hypoxia and DNA repair. The Yale Journal of Biology and Medicine. 86: 443-51. PMID 24348208 |
0.332 |
|
| 2013 |
Schleifman EB, McNeer NA, Jackson A, Yamtich J, Brehm MA, Shultz LD, Greiner DL, Kumar P, Saltzman WM, Glazer PM. Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice. Molecular Therapy. Nucleic Acids. 2: e135. PMID 24253260 DOI: 10.1038/Mtna.2013.59 |
0.801 |
|
| 2013 |
Bahal R, McNeer NA, Ly DH, Saltzman WM, Glazer PM. Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5. Artificial Dna, Pna & Xna. 4: 49-57. PMID 23954968 DOI: 10.4161/adna.25628 |
0.81 |
|
| 2013 |
Shahbazian D, Bindra RS, Kluger HM, Glazer PM. Radiation sensitivity and sensitization in melanoma. Pigment Cell & Melanoma Research. 26: 928-30. PMID 23870422 DOI: 10.1111/Pcmr.12147 |
0.553 |
|
| 2013 |
Chin JY, Reza F, Glazer PM. Triplex-forming peptide nucleic acids induce heritable elevations in gamma-globin expression in hematopoietic progenitor cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 580-7. PMID 23337982 DOI: 10.1038/Mt.2012.262 |
0.832 |
|
| 2013 |
McNeer NA, Schleifman EB, Cuthbert A, Brehm M, Jackson A, Cheng C, Anandalingam K, Kumar P, Shultz LD, Greiner DL, Mark Saltzman W, Glazer PM. Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo. Gene Therapy. 20: 658-69. PMID 23076379 DOI: 10.1038/Gt.2012.82 |
0.839 |
|
| 2013 |
Hansen JE, Chan G, Liu Y, Hegan DC, Dalal S, Dray E, Kwon Y, Xu Y, Xu X, Peterson-Roth E, Geiger E, Liu Y, Gera J, Sweasy JB, Sung P, ... ... Glazer PM, et al. Abstract 4319: Lupus antibody-based cancer therapy. Cancer Research. 73: 4319-4319. DOI: 10.1158/1538-7445.Am2013-4319 |
0.41 |
|
| 2013 |
Lu Y, Wajapeyee N, Turker MS, Glazer PM. Abstract 1513:MLH1silencing is caused by hypoxia through epigenetic regulation.. Cancer Research. 73: 1513-1513. DOI: 10.1158/1538-7445.Am2013-1513 |
0.387 |
|
| 2012 |
Hansen JE, Chan G, Liu Y, Hegan DC, Dalal S, Dray E, Kwon Y, Xu Y, Xu X, Peterson-Roth E, Geiger E, Liu Y, Gera J, Sweasy JB, Sung P, ... ... Glazer PM, et al. Targeting cancer with a lupus autoantibody. Science Translational Medicine. 4: 157ra142. PMID 23100628 DOI: 10.1126/Scitranslmed.3004385 |
0.423 |
|
| 2012 |
Meng F, Evans JW, Bhupathi D, Banica M, Lan L, Lorente G, Duan JX, Cai X, Mowday AM, Guise CP, Maroz A, Anderson RF, Patterson AV, Stachelek GC, Glazer PM, et al. Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302. Molecular Cancer Therapeutics. 11: 740-51. PMID 22147748 DOI: 10.1158/1535-7163.Mct-11-0634 |
0.343 |
|
| 2012 |
Rogers FA, Lin SS, Hegan DC, Krause DS, Glazer PM. Targeted gene modification of hematopoietic progenitor cells in mice following systemic administration of a PNA-peptide conjugate. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 109-18. PMID 21829173 DOI: 10.1038/Mt.2011.163 |
0.413 |
|
| 2012 |
Hansen J, Chan G, Liu Y, Gera J, Sweasy J, Sung P, Rockwell S, Nishimura R, Weisbart R, Glazer P. A Rare Cell-penetrating Anti-DNA Antibody Inhibits DNA Repair, Sensitizes Tumors To DNA-damaging Therapy, and is Synthetically Lethal to BRCA2-deficient Cancer Cells International Journal of Radiation Oncology*Biology*Physics. 84: S163. DOI: 10.1016/J.Ijrobp.2012.07.422 |
0.426 |
|
| 2012 |
Klein T, Glazer P, Xu T. Ras Promotes Nonautonomous Cell Death in Response to Radiation: Insights From a Novel Drosophila-based Model of Radiation Therapy International Journal of Radiation Oncology*Biology*Physics. 84: S667. DOI: 10.1016/J.Ijrobp.2012.07.1781 |
0.318 |
|
| 2011 |
Schleifman EB, Bindra R, Leif J, del Campo J, Rogers FA, Uchil P, Kutsch O, Shultz LD, Kumar P, Greiner DL, Glazer PM. Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids. Chemistry & Biology. 18: 1189-98. PMID 21944757 DOI: 10.1016/J.Chembiol.2011.07.010 |
0.795 |
|
| 2011 |
Lin ZP, Lee Y, Lin F, Belcourt MF, Li P, Cory JG, Glazer PM, Sartorelli AC. Reduced level of ribonucleotide reductase R2 subunits increases dependence on homologous recombination repair of cisplatin-induced DNA damage. Molecular Pharmacology. 80: 1000-12. PMID 21875941 DOI: 10.1124/Mol.111.074708 |
0.367 |
|
| 2011 |
Williams SA, Wilson JB, Clark AP, Mitson-Salazar A, Tomashevski A, Ananth S, Glazer PM, Semmes OJ, Bale AE, Jones NJ, Kupfer GM. Functional and physical interaction between the mismatch repair and FA-BRCA pathways. Human Molecular Genetics. 20: 4395-410. PMID 21865299 DOI: 10.1182/Blood.V116.21.3370.3370 |
0.393 |
|
| 2011 |
Lu Y, Chu A, Turker MS, Glazer PM. Hypoxia-induced epigenetic regulation and silencing of the BRCA1 promoter. Molecular and Cellular Biology. 31: 3339-50. PMID 21670155 DOI: 10.1128/Mcb.01121-10 |
0.369 |
|
| 2011 |
McNeer NA, Schleifman EB, Glazer PM, Saltzman WM. Polymer delivery systems for site-specific genome editing. Journal of Controlled Release : Official Journal of the Controlled Release Society. 155: 312-6. PMID 21620910 DOI: 10.1016/J.Jconrel.2011.05.011 |
0.817 |
|
| 2011 |
McNeer NA, Chin JY, Schleifman EB, Fields RJ, Glazer PM, Saltzman WM. Nanoparticles deliver triplex-forming PNAs for site-specific genomic recombination in CD34+ human hematopoietic progenitors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 172-80. PMID 20859257 DOI: 10.1038/Mt.2010.200 |
0.816 |
|
| 2011 |
Hegan DC, Glazer PM. Abstract 3893: Mechanism of radiosensitization by inhibitors of poly(ADP-ribose) polymerase (PARP) Cancer Research. 71: 3893-3893. DOI: 10.1158/1538-7445.Am2011-3893 |
0.443 |
|
| 2010 |
Klein TJ, Glazer PM. The tumor microenvironment and DNA repair. Seminars in Radiation Oncology. 20: 282-7. PMID 20832021 DOI: 10.1016/J.Semradonc.2010.05.006 |
0.408 |
|
| 2010 |
Rowe BP, Glazer PM. Emergence of rationally designed therapeutic strategies for breast cancer targeting DNA repair mechanisms. Breast Cancer Research : Bcr. 12: 203. PMID 20459590 DOI: 10.1186/Bcr2566 |
0.368 |
|
| 2010 |
Hegan DC, Lu Y, Stachelek GC, Crosby ME, Bindra RS, Glazer PM. Inhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130. Proceedings of the National Academy of Sciences of the United States of America. 107: 2201-6. PMID 20133863 DOI: 10.1073/Pnas.0904783107 |
0.638 |
|
| 2010 |
Stachelek GC, Dalal S, Donigan KA, Campisi Hegan D, Sweasy JB, Glazer PM. Potentiation of temozolomide cytotoxicity by inhibition of DNA polymerase beta is accentuated by BRCA2 mutation. Cancer Research. 70: 409-17. PMID 20028873 DOI: 10.1158/0008-5472.Can-09-1353 |
0.463 |
|
| 2010 |
Peterson-Roth E, Abriola L, Merkel J, Glazer P. Abstract 2185: Identification of novel compounds that preferentially kill repair deficient cells using high-throughput screening Cancer Research. 70: 2185-2185. DOI: 10.1158/1538-7445.Am10-2185 |
0.351 |
|
| 2010 |
Hegan DC, Lu Y, Stachelek GC, Crosby ME, Bindra RS, Glazer PM. Abstract 1969: Inhibition of poly(ADP-ribose) polymerase downregulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130 Cancer Research. 70: 1969-1969. DOI: 10.1158/1538-7445.Am10-1969 |
0.626 |
|
| 2009 |
Crosby ME, Glazer PM, Ivan M. "Micro"-management of DNA repair genes by hypoxia Cell Cycle. 8: 4009-4010. PMID 19949295 DOI: 10.4161/Cc.8.24.10211 |
0.409 |
|
| 2009 |
Kim Y, Lin Q, Glazer PM, Yun Z. Hypoxic tumor microenvironment and cancer cell differentiation. Current Molecular Medicine. 9: 425-34. PMID 19519400 DOI: 10.2174/156652409788167113 |
0.319 |
|
| 2009 |
Glazer PM, Bindra RS. Introduction: the evolving picture of the hypoxic tumour microenvironment. Current Molecular Medicine. 9: 399-400. PMID 19519396 DOI: 10.2174/156652409788167069 |
0.514 |
|
| 2009 |
Lonkar P, Kim KH, Kuan JY, Chin JY, Rogers FA, Knauert MP, Kole R, Nielsen PE, Glazer PM. Targeted correction of a thalassemia-associated beta-globin mutation induced by pseudo-complementary peptide nucleic acids. Nucleic Acids Research. 37: 3635-44. PMID 19364810 DOI: 10.1093/Nar/Gkp217 |
0.821 |
|
| 2009 |
Peterson-Roth E, Brdlik CM, Glazer PM. Src-Induced cisplatin resistance mediated by cell-to-cell communication. Cancer Research. 69: 3619-24. PMID 19351863 DOI: 10.1158/0008-5472.Can-08-0985 |
0.344 |
|
| 2009 |
Chin JY, Glazer PM. Repair of DNA lesions associated with triplex-forming oligonucleotides. Molecular Carcinogenesis. 48: 389-99. PMID 19072762 DOI: 10.1002/Mc.20501 |
0.82 |
|
| 2009 |
Crosby ME, Kulshreshtha R, Ivan M, Glazer PM. Erratum: Article on MicroRNAs and DNA repair (Cancer Res (2009) 69 (1221:1229)) Cancer Research. 69. DOI: 10.1158/0008-5472.Can-69-7-Cor3 |
0.365 |
|
| 2009 |
Glazer P, Stachelek G, Dalal S, Sweasy J. Targeting Base Excision Repair to Potentiate Cancer Therapy International Journal of Radiation Oncology*Biology*Physics. 75: S21. DOI: 10.1016/J.Ijrobp.2009.07.071 |
0.331 |
|
| 2008 |
Chin JY, Kuan JY, Lonkar PS, Krause DS, Seidman MM, Peterson KR, Nielsen PE, Kole R, Glazer PM. Correction of a splice-site mutation in the beta-globin gene stimulated by triplex-forming peptide nucleic acids. Proceedings of the National Academy of Sciences of the United States of America. 105: 13514-9. PMID 18757759 DOI: 10.1073/Pnas.0711793105 |
0.816 |
|
| 2008 |
Schleifman EB, Chin JY, Glazer PM. Triplex-mediated gene modification. Methods in Molecular Biology (Clifton, N.J.). 435: 175-90. PMID 18370076 DOI: 10.1007/978-1-59745-232-8_13 |
0.819 |
|
| 2008 |
Marek LR, Kottemann MC, Glazer PM, Bale AE. MEN1 and FANCD2 mediate distinct mechanisms of DNA crosslink repair. Dna Repair. 7: 476-86. PMID 18258493 DOI: 10.1016/J.Dnarep.2007.12.009 |
0.38 |
|
| 2008 |
Chan N, Koritzinsky M, Zhao H, Bindra R, Glazer PM, Powell S, Belmaaza A, Wouters B, Bristow RG. Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance. Cancer Research. 68: 605-14. PMID 18199558 DOI: 10.1158/0008-5472.Can-07-5472 |
0.638 |
|
| 2007 |
Kim KH, Nielsen PE, Glazer PM. Site-directed gene mutation at mixed sequence targets by psoralen-conjugated pseudo-complementary peptide nucleic acids. Nucleic Acids Research. 35: 7604-13. PMID 17977869 DOI: 10.1093/Nar/Gkm666 |
0.518 |
|
| 2007 |
Chin JY, Schleifman EB, Glazer PM. Repair and recombination induced by triple helix DNA. Frontiers in Bioscience : a Journal and Virtual Library. 12: 4288-97. PMID 17485375 DOI: 10.2741/2388 |
0.826 |
|
| 2007 |
Bindra RS, Crosby ME, Glazer PM. Regulation of DNA repair in hypoxic cancer cells Cancer and Metastasis Reviews. 26: 249-260. PMID 17415527 DOI: 10.1007/S10555-007-9061-3 |
0.65 |
|
| 2007 |
Bindra RS, Glazer PM. Co-repression of mismatch repair gene expression by hypoxia in cancer cells: role of the Myc/Max network. Cancer Letters. 252: 93-103. PMID 17275176 DOI: 10.1016/J.Canlet.2006.12.011 |
0.661 |
|
| 2007 |
Huang LE, Bindra RS, Glazer PM, Harris AL. Hypoxia-induced genetic instability--a calculated mechanism underlying tumor progression. Journal of Molecular Medicine (Berlin, Germany). 85: 139-48. PMID 17180667 DOI: 10.1007/S00109-006-0133-6 |
0.596 |
|
| 2007 |
Bindra RS, Glazer PM. Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia. Oncogene. 26: 2048-57. PMID 17001309 DOI: 10.1038/Sj.Onc.1210001 |
0.662 |
|
| 2007 |
Mani S, Moradi A, Abdolahi N, Martel M, Semnani S, Glazer P, Mani A. The Aberrant Expression of Beta-catenin in Esophageal Squamous Cell Cancer (ESCC) in Northeastern Iran International Journal of Radiation Oncology*Biology*Physics. 69: S309-S310. DOI: 10.1016/J.Ijrobp.2007.07.1366 |
0.332 |
|
| 2006 |
Bindra RS, Glazer PM. Basal repression of BRCA1 by multiple E2Fs and pocket proteins at adjacent E2F sites. Cancer Biology & Therapy. 5: 1400-7. PMID 17106239 DOI: 10.4161/Cbt.5.10.3454 |
0.637 |
|
| 2006 |
Gibson SL, Bindra RS, Glazer PM. CHK2-dependent phosphorylation of BRCA1 in hypoxia. Radiation Research. 166: 646-51. PMID 17007555 DOI: 10.1667/Rr0660.1 |
0.808 |
|
| 2006 |
Knauert MP, Kalish JM, Hegan DC, Glazer PM. Triplex-stimulated intermolecular recombination at a single-copy genomic target. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 392-400. PMID 16731047 DOI: 10.1016/J.Ymthe.2006.03.020 |
0.791 |
|
| 2006 |
Hegan DC, Narayanan L, Jirik FR, Edelmann W, Liskay RM, Glazer PM. Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6. Carcinogenesis. 27: 2402-8. PMID 16728433 DOI: 10.1093/Carcin/Bgl079 |
0.331 |
|
| 2006 |
Zheng H, Wang X, Legerski RJ, Glazer PM, Li L. Repair of DNA interstrand cross-links: interactions between homology-dependent and homology-independent pathways. Dna Repair. 5: 566-74. PMID 16569514 DOI: 10.1016/J.Dnarep.2006.01.010 |
0.431 |
|
| 2006 |
Shahid KA, Majumdar A, Alam R, Liu ST, Kuan JY, Sui X, Cuenoud B, Glazer PM, Miller PS, Seidman MM. Targeted cross-linking of the human beta-globin gene in living cells mediated by a triple helix forming oligonucleotide. Biochemistry. 45: 1970-8. PMID 16460044 DOI: 10.1021/Bi0520986 |
0.812 |
|
| 2006 |
Smith-Roe SL, Löhr CV, Bildfell RJ, Fischer KA, Hegan DC, Glazer PM, Buermeyer AB. Induction of aberrant crypt foci in DNA mismatch repair-deficient mice by the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP). Cancer Letters. 244: 79-85. PMID 16427736 DOI: 10.1016/J.Canlet.2005.12.002 |
0.362 |
|
| 2006 |
Gibson SL, Narayanan L, Hegan DC, Buermeyer AB, Liskay RM, Glazer PM. Overexpression of the DNA mismatch repair factor, PMS2, confers hypermutability and DNA damage tolerance. Cancer Letters. 244: 195-202. PMID 16426742 DOI: 10.1016/J.Canlet.2005.12.009 |
0.839 |
|
| 2006 |
Kim KH, Nielsen PE, Glazer PM. Site-specific gene modification by PNAs conjugated to psoralen. Biochemistry. 45: 314-23. PMID 16388608 DOI: 10.1021/Bi051379A |
0.483 |
|
| 2006 |
Smith-Roe SL, Hegan DC, Glazer PM, Buermeyer AB. Mlh1-dependent suppression of specific mutations induced in vivo by the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP). Mutation Research. 594: 101-12. PMID 16256150 DOI: 10.1016/J.Mrfmmm.2005.08.011 |
0.338 |
|
| 2006 |
Kalish JM, Knauert MP, Hegan DC, Glazer PM. 708. Gene Targeting with Triplex-Forming Oligonucletides in the Pyrimidine Motif Molecular Therapy. 13: S273-S274. DOI: 10.1016/J.Ymthe.2006.08.787 |
0.782 |
|
| 2006 |
Rogers FA, Glazer PM. 1031. Improved Intranuclear Delivery of PNA- Peptide Conjugates Designed for Chromosomal Gene Targeting Molecular Therapy. 13: S396. DOI: 10.1016/J.Ymthe.2006.08.1126 |
0.462 |
|
| 2006 |
Chin JY, Lloyd JA, Rogers FA, Glazer PM. 1030. Pyrazolo[3,4-d]Pyrimidine Guanine Base Substitution in Triplex Forming Oligonucleotides Improves Target Specificity and Chromosomal Mutagenesis Molecular Therapy. 13: S396. DOI: 10.1016/J.Ymthe.2006.08.1125 |
0.819 |
|
| 2006 |
Kuan JY, Kole R, Nielsen PE, Glazer PM. 89. Gene Targeting of β_Globin IVS2 Using Sequence_Specific Peptide Nucleic Acids Molecular Therapy. 13: S37. DOI: 10.1016/J.Ymthe.2006.08.107 |
0.823 |
|
| 2006 |
Bindra R, Gibson S, Crosby M, Glazer P. 86 International Journal of Radiation Oncology*Biology*Physics. 66: S50. DOI: 10.1016/J.Ijrobp.2006.07.116 |
0.768 |
|
| 2005 |
Kalish JM, Glazer PM. Targeted genome modification via triple helix formation. Annals of the New York Academy of Sciences. 1058: 151-61. PMID 16394134 DOI: 10.1196/Annals.1359.023 |
0.522 |
|
| 2005 |
Bindra RS, Schaffer PJ, Meng A, Woo J, Måseide K, Roth ME, Lizardi P, Hedley DW, Bristow RG, Glazer PM. Alterations in DNA repair gene expression under hypoxia: elucidating the mechanisms of hypoxia-induced genetic instability. Annals of the New York Academy of Sciences. 1059: 184-95. PMID 16382054 DOI: 10.1196/Annals.1339.049 |
0.662 |
|
| 2005 |
Bindra RS, Gibson SL, Meng A, Westermark U, Jasin M, Pierce AJ, Bristow RG, Classon MK, Glazer PM. Hypoxia-induced down-regulation of BRCA1 expression by E2Fs. Cancer Research. 65: 11597-604. PMID 16357170 DOI: 10.1158/0008-5472.Can-05-2119 |
0.816 |
|
| 2005 |
Gibson SL, Bindra RS, Glazer PM. Hypoxia-induced phosphorylation of Chk2 in an ataxia telangiectasia mutated-dependent manner. Cancer Research. 65: 10734-41. PMID 16322218 DOI: 10.1158/0008-5472.Can-05-1160 |
0.813 |
|
| 2005 |
Lewin AS, Glazer PM, Milstone LM. Gene therapy for autosomal dominant disorders of keratin. The Journal of Investigative Dermatology. Symposium Proceedings / the Society For Investigative Dermatology, Inc. [and] European Society For Dermatological Research. 10: 47-61. PMID 16250209 DOI: 10.1111/J.1087-0024.2005.10207.X |
0.364 |
|
| 2005 |
Rogers FA, Lloyd JA, Glazer PM. Triplex-forming oligonucleotides as potential tools for modulation of gene expression. Current Medicinal Chemistry. Anti-Cancer Agents. 5: 319-26. PMID 16101484 DOI: 10.2174/1568011054222300 |
0.487 |
|
| 2005 |
Meng AX, Jalali F, Cuddihy A, Chan N, Bindra RS, Glazer PM, Bristow RG. Hypoxia down-regulates DNA double strand break repair gene expression in prostate cancer cells. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 76: 168-76. PMID 16026872 DOI: 10.1016/J.Radonc.2005.06.025 |
0.622 |
|
| 2005 |
Kalish JM, Seidman MM, Weeks DL, Glazer PM. Triplex-induced recombination and repair in the pyrimidine motif. Nucleic Acids Research. 33: 3492-502. PMID 15961731 DOI: 10.1093/Nar/Gki659 |
0.505 |
|
| 2005 |
Knauert MP, Lloyd JA, Rogers FA, Datta HJ, Bennett ML, Weeks DL, Glazer PM. Distance and affinity dependence of triplex-induced recombination. Biochemistry. 44: 3856-64. PMID 15751961 DOI: 10.1021/Bi0481040 |
0.757 |
|
| 2005 |
Bindra RS, Glazer PM. Genetic instability and the tumor microenvironment: towards the concept of microenvironment-induced mutagenesis. Mutation Research. 569: 75-85. PMID 15603753 DOI: 10.1016/J.Mrfmmm.2004.03.013 |
0.618 |
|
| 2005 |
Bristow R, Meng A, Jalali F, Hedley D, Nichol T, Sweet J, Milosevic M, Bindra R, Glazer P. 67 Expression of DNA-dsb repair proteins is altered under hypoxia in prostate cancer cells Radiotherapy and Oncology. 76: S20-S21. DOI: 10.1016/S0167-8140(05)80228-2 |
0.607 |
|
| 2005 |
Glazer PM, Rogers F, Lloyd J. 369. Targeted Gene Modification Via Triple Helix-Forming Oligonucleotides Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.372 |
0.542 |
|
| 2005 |
Glazer P, Bindra R. Dysregulation of BRCAL in Hypoxia International Journal of Radiation Oncology*Biology*Physics. 63: S145. DOI: 10.1016/J.Ijrobp.2005.07.247 |
0.512 |
|
| 2004 |
Rogers FA, Manoharan M, Rabinovitch P, Ward DC, Glazer PM. Peptide conjugates for chromosomal gene targeting by triplex-forming oligonucleotides. Nucleic Acids Research. 32: 6595-604. PMID 15602001 DOI: 10.1093/Nar/Gkh998 |
0.459 |
|
| 2004 |
Bindra RS, Schaffer PJ, Meng A, Woo J, Måseide K, Roth ME, Lizardi P, Hedley DW, Bristow RG, Glazer PM. Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells. Molecular and Cellular Biology. 24: 8504-18. PMID 15367671 DOI: 10.1128/Mcb.24.19.8504-8518.2004 |
0.671 |
|
| 2004 |
Seidman MM, Glazer PM. Setting standards in gene repair. Oligonucleotides. 14: 79. PMID 15294071 DOI: 10.1089/1545457041526263 |
0.343 |
|
| 2004 |
Jensen R, Glazer PM. Cell-interdependent cisplatin killing by Ku/DNA-dependent protein kinase signaling transduced through gap junctions. Proceedings of the National Academy of Sciences of the United States of America. 101: 6134-9. PMID 15069205 DOI: 10.1073/Pnas.0400051101 |
0.418 |
|
| 2004 |
Kuan JY, Glazer PM. Targeted gene modification using triplex-forming oligonucleotides. Methods in Molecular Biology (Clifton, N.J.). 262: 173-94. PMID 14769962 DOI: 10.1385/1-59259-761-0:173 |
0.838 |
|
| 2003 |
Haffty BG, Glazer PM. Molecular markers in clinical radiation oncology. Oncogene. 22: 5915-25. PMID 12947398 DOI: 10.1038/Sj.Onc.1206704 |
0.312 |
|
| 2003 |
Seidman MM, Glazer PM. The potential for gene repair via triple helix formation. The Journal of Clinical Investigation. 112: 487-94. PMID 12925687 DOI: 10.1172/Jci19552 |
0.491 |
|
| 2003 |
Mihaylova VT, Bindra RS, Yuan J, Campisi D, Narayanan L, Jensen R, Giordano F, Johnson RS, Rockwell S, Glazer PM. Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells. Molecular and Cellular Biology. 23: 3265-73. PMID 12697826 DOI: 10.1128/Mcb.23.9.3265-3273.2003 |
0.785 |
|
| 2003 |
Macris MA, Glazer PM. Transcription dependence of chromosomal gene targeting by triplex-forming oligonucleotides. The Journal of Biological Chemistry. 278: 3357-62. PMID 12431993 DOI: 10.1074/Jbc.M206542200 |
0.823 |
|
| 2003 |
Glazer P. Decreased expression of the DNA mismatch repair gene, Mlh1, under hypoxic stress in mammalian cells International Journal of Radiation Oncology*Biology*Physics. 57: S143-S144. DOI: 10.1016/S0360-3016(03)00903-9 |
0.335 |
|
| 2003 |
Wang G, Glazer PM. Peptide nucleic acids as agents to modify target gene expression and function International Journal of Peptide Research and Therapeutics. 10: 335-345. DOI: 10.1007/S10989-004-4903-0 |
0.368 |
|
| 2002 |
Rogers FA, Vasquez KM, Egholm M, Glazer PM. Site-directed recombination via bifunctional PNA-DNA conjugates. Proceedings of the National Academy of Sciences of the United States of America. 99: 16695-700. PMID 12461167 DOI: 10.1073/Pnas.262556899 |
0.507 |
|
| 2002 |
Peretz S, Kim C, Rockwell S, Baserga R, Glazer PM. IGF1 receptor expression protects against microenvironmental stress found in the solid tumor. Radiation Research. 158: 174-80. PMID 12105987 DOI: 10.1667/0033-7587(2002)158[0174:Irepam]2.0.Co;2 |
0.796 |
|
| 2002 |
Vasquez KM, Glazer PM. Triplex-forming oligonucleotides: principles and applications. Quarterly Reviews of Biophysics. 35: 89-107. PMID 11997982 DOI: 10.1017/S0033583502003773 |
0.38 |
|
| 2002 |
Vasquez KM, Christensen J, Li L, Finch RA, Glazer PM. Human XPA and RPA DNA repair proteins participate in specific recognition of triplex-induced helical distortions. Proceedings of the National Academy of Sciences of the United States of America. 99: 5848-53. PMID 11972036 DOI: 10.1073/Pnas.082193799 |
0.421 |
|
| 2002 |
Gorman L, Glazer PM. Directed gene modification via triple helix formation. Current Molecular Medicine. 1: 391-9. PMID 11899085 DOI: 10.2174/1566524013363771 |
0.499 |
|
| 2002 |
Glazer P, Narayanan L, Liskay M, Campisi D. Over-expression of the DNA mismatch repair factor, PMS2, confers ionizing radiation resistance and hypermutability International Journal of Radiation Oncology*Biology*Physics. 54: 51-52. DOI: 10.1016/S0360-3016(02)03145-0 |
0.353 |
|
| 2001 |
Datta HJ, Glazer PM. Intracellular generation of single-stranded DNA for chromosomal triplex formation and induced recombination. Nucleic Acids Research. 29: 5140-7. PMID 11812847 DOI: 10.1093/Nar/29.24.5140 |
0.48 |
|
| 2001 |
Rockwell S, Yuan J, Peretz S, Glazer PM. Genomic instability in cancer. Novartis Foundation Symposium. 240: 133-42; discussion 1. PMID 11727926 DOI: 10.1002/0470868716.Ch9 |
0.818 |
|
| 2001 |
Knauert MP, Glazer PM. Triplex forming oligonucleotides: sequence-specific tools for gene targeting. Human Molecular Genetics. 10: 2243-51. PMID 11673407 DOI: 10.1093/Hmg/10.20.2243 |
0.769 |
|
| 2001 |
Casey BP, Glazer PM. Gene targeting via triple-helix formation Progress in Nucleic Acid Research and Molecular Biology. 67: 163-192. PMID 11525382 DOI: 10.1016/S0079-6603(01)67028-4 |
0.482 |
|
| 2001 |
Vasquez KM, Dagle JM, Weeks DL, Glazer PM. Chromosome targeting at short polypurine sites by cationic triplex-forming oligonucleotides. The Journal of Biological Chemistry. 276: 38536-41. PMID 11504712 DOI: 10.1074/Jbc.M101797200 |
0.417 |
|
| 2001 |
Datta HJ, Chan PP, Vasquez KM, Gupta RC, Glazer PM. Triplex-induced recombination in human cell-free extracts. Dependence on XPA and HsRad51. The Journal of Biological Chemistry. 276: 18018-23. PMID 11278954 DOI: 10.1074/Jbc.M011646200 |
0.75 |
|
| 2001 |
Peretz S, Jensen R, Baserga R, Glazer PM. ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiation response. Proceedings of the National Academy of Sciences of the United States of America. 98: 1676-81. PMID 11172010 DOI: 10.1073/Pnas.98.4.1676 |
0.784 |
|
| 2001 |
Glazer P, Peretz S, Jensen R, Gibson S. ATM-dependent expression of the IGF-I receptor in a pathway regulating radiation response International Journal of Radiation Oncology*Biology*Physics. 51: 55. DOI: 10.1016/S0360-3016(01)01923-X |
0.767 |
|
| 2000 |
Vasquez KM, Narayanan L, Glazer PM. Specific mutations induced by triplex-forming oligonucleotides in mice. Science (New York, N.Y.). 290: 530-3. PMID 11039937 DOI: 10.1126/Science.290.5491.530 |
0.442 |
|
| 2000 |
Yuan J, Narayanan L, Rockwell S, Glazer PM. Diminished DNA repair and elevated mutagenesis in mammalian cells exposed to hypoxia and low pH. Cancer Research. 60: 4372-6. PMID 10969780 DOI: 10.1016/S0360-3016(00)80378-8 |
0.715 |
|
| 2000 |
Luo Z, Macris MA, Faruqi AF, Glazer PM. High-frequency intrachromosomal gene conversion induced by triplex-forming oligonucleotides microinjected into mouse cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 9003-8. PMID 10900269 DOI: 10.1073/Pnas.160004997 |
0.825 |
|
| 2000 |
Andrew SE, Xu XS, Baross-Francis A, Narayanan L, Milhausen K, Liskay RM, Jirik FR, Glazer PM. Mutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions and frameshifts. Carcinogenesis. 21: 1291-5. PMID 10874005 DOI: 10.1093/Carcin/21.7.1291 |
0.337 |
|
| 2000 |
Xu XS, Glazer PM, Wang G. Activation of human gamma-globin gene expression via triplex-forming oligonucleotide (TFO)-directed mutations in the gamma-globin gene 5' flanking region. Gene. 242: 219-28. PMID 10721715 DOI: 10.1016/S0378-1119(99)00522-3 |
0.478 |
|
| 2000 |
Turner BC, Gumbs AA, Carbone CJ, Carter D, Glazer PM, Haffty BG. Mutant p53 protein overexpression in women with ipsilateral breast tumor recurrence following lumpectomy and radiation therapy. Cancer. 88: 1091-8. PMID 10699900 DOI: 10.1002/(Sici)1097-0142(20000301)88:5<1091::Aid-Cncr21>3.0.Co;2-Y |
0.361 |
|
| 2000 |
Faruqi AF, Datta HJ, Carroll D, Seidman MM, Glazer PM. Triple-helix formation induces recombination in mammalian cells via a nucleotide excision repair-dependent pathway. Molecular and Cellular Biology. 20: 990-1000. PMID 10629056 DOI: 10.1128/Mcb.20.3.990-1000.2000 |
0.535 |
|
| 2000 |
Glazer PM. DNA Repair Protocols: Eukaryotic Systems Radiation Research. 153: 241-242. DOI: 10.1667/0033-7587(2000)153[0241:Drpes]2.0.Co;2 |
0.359 |
|
| 2000 |
Glazer PM. Better than the real thing: peptide nucleic acids Trends in Genetics. 16: 278. DOI: 10.1016/S0168-9525(00)01994-6 |
0.411 |
|
| 1999 |
Clairmont CA, Narayanan L, Sun KW, Glazer PM, Sweasy JB. The Tyr-265-to-Cys mutator mutant of DNA polymerase beta induces a mutator phenotype in mouse LN12 cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 9580-5. PMID 10449735 DOI: 10.1073/Pnas.96.17.9580 |
0.406 |
|
| 1999 |
Wang G, Xu X, Pace B, Dean DA, Glazer PM, Chan P, Goodman SR, Shokolenko I. Peptide nucleic acid (PNA) binding-mediated induction of human gamma-globin gene expression. Nucleic Acids Research. 27: 2806-13. PMID 10373600 DOI: 10.1093/Nar/27.13.2806 |
0.762 |
|
| 1999 |
Yao X, Buermeyer AB, Narayanan L, Tran D, Baker SM, Prolla TA, Glazer PM, Liskay RM, Arnheim N. Different mutator phenotypes in Mlh1- versus Pms2-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 6850-5. PMID 10359802 DOI: 10.1073/Pnas.96.12.6850 |
0.36 |
|
| 1999 |
Chan PP, Lin M, Faruqi AF, Powell J, Seidman MM, Glazer PM. Targeted correction of an episomal gene in mammalian cells by a short DNA fragment tethered to a triplex-forming oligonucleotide. The Journal of Biological Chemistry. 274: 11541-8. PMID 10206960 DOI: 10.1074/Jbc.274.17.11541 |
0.763 |
|
| 1999 |
Lacroix L, Lacoste J, Reddoch JF, Mergny JL, Levy DD, Seidman MM, Matteucci MD, Glazer PM. Triplex formation by oligonucleotides containing 5-(1-propynyl)-2'-deoxyuridine: decreased magnesium dependence and improved intracellular gene targeting. Biochemistry. 38: 1893-901. PMID 10026270 DOI: 10.1021/Bi982290Q |
0.763 |
|
| 1999 |
Vasquez KM, Wang G, Havre PA, Glazer PM. Chromosomal mutations induced by triplex-forming oligonucleotides in mammalian cells. Nucleic Acids Research. 27: 1176-81. PMID 9927753 DOI: 10.1093/Nar/27.4.1176 |
0.44 |
|
| 1999 |
Peretz S, Kim C, Rockwell S, Baserga R, Glazer P. 105 Tumor hypoxia induces and selects for overexpression of the igf-i receptor: Implications for tumor progression and radioresistance International Journal of Radiation Oncology*Biology*Physics. 45: 201. DOI: 10.1016/S0360-3016(99)90123-2 |
0.768 |
|
| 1998 |
Majumdar A, Khorlin A, Dyatkina N, Lin FL, Powell J, Liu J, Fei Z, Khripine Y, Watanabe KA, George J, Glazer PM, Seidman MM. Targeted gene knockout mediated by triple helix forming oligonucleotides. Nature Genetics. 20: 212-4. PMID 9771719 DOI: 10.1038/2530 |
0.489 |
|
| 1998 |
Yuan J, Glazer PM. Mutagenesis induced by the tumor microenvironment. Mutation Research. 400: 439-46. PMID 9685702 DOI: 10.1016/S0027-5107(98)00042-6 |
0.661 |
|
| 1998 |
Faruqi AF, Egholm M, Glazer PM. Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells. Proceedings of the National Academy of Sciences of the United States of America. 95: 1398-403. PMID 9465026 DOI: 10.1073/Pnas.95.4.1398 |
0.517 |
|
| 1998 |
Raha M, Lacroix L, Glazer PM. Mutagenesis Mediated by Triple Helix–Forming Oligonucleotides Conjugated to Psoralen: Effects of Linker Arm Length and Sequence Context Photochemistry and Photobiology. 67: 289-294. DOI: 10.1111/J.1751-1097.1998.Tb05201.X |
0.701 |
|
| 1998 |
Glazer P, Fritzell J, Narayanan L. Role of DNA mismatch repair in response to ionizing radiation International Journal of Radiation Oncology*Biology*Physics. 42: 154. DOI: 10.1016/S0360-3016(98)80160-0 |
0.352 |
|
| 1997 |
Segal DJ, Faruqi AF, Glazer PM, Carroll D. Processing of targeted psoralen cross-links in Xenopus oocytes. Molecular and Cellular Biology. 17: 6645-52. PMID 9343428 DOI: 10.1128/Mcb.17.11.6645 |
0.433 |
|
| 1997 |
Turner BC, Haffty BG, Narayanan L, Yuan J, Havre PA, Gumbs AA, Kaplan L, Burgaud JL, Carter D, Baserga R, Glazer PM. Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation. Cancer Research. 57: 3079-83. PMID 9242428 |
0.618 |
|
| 1997 |
Chan PP, Glazer PM. Triplex DNA: fundamentals, advances, and potential applications for gene therapy. Journal of Molecular Medicine (Berlin, Germany). 75: 267-82. PMID 9151213 DOI: 10.1007/S001090050112 |
0.755 |
|
| 1997 |
Narayanan L, Fritzell JA, Baker SM, Liskay RM, Glazer PM. Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2. Proceedings of the National Academy of Sciences of the United States of America. 94: 3122-7. PMID 9096356 DOI: 10.1073/Pnas.94.7.3122 |
0.431 |
|
| 1997 |
Faruqi AF, Krawczyk SH, Matteucci MD, Glazer PM. Potassium-resistant triple helix formation and improved intracellular gene targeting by oligodeoxyribonucleotides containing 7-deazaxanthine. Nucleic Acids Research. 25: 633-40. PMID 9016606 DOI: 10.1093/Nar/25.3.633 |
0.449 |
|
| 1997 |
Faruqi AF, Seidman MM, Segal DJ, Carroll D, Glazer PM. Recombination induced by triple-helix-targeted DNA damage in mammalian cells. Molecular and Cellular Biology. 16: 6820-8. PMID 8943337 DOI: 10.1128/Mcb.16.12.6820 |
0.529 |
|
| 1996 |
Leach EG, Narayanan L, Havre PA, Gunther EJ, Yeasky TM, Glazer PM. Tissue specificity of spontaneous point mutations in lambda supF transgenic mice. Environmental and Molecular Mutagenesis. 28: 459-64. PMID 8991078 DOI: 10.1002/(Sici)1098-2280(1996)28:4<459::Aid-Em23>3.0.Co;2-D |
0.344 |
|
| 1996 |
Glazer PM, Wang G, Havre PA, Gunther EJ. Targeted mutagenesis mediated by the triple helix formation. Methods in Molecular Biology (Clifton, N.J.). 57: 109-18. PMID 8849999 DOI: 10.1385/0-89603-332-5:109 |
0.329 |
|
| 1996 |
Leach EG, Gunther EJ, Yeasky TM, Gibson LH, Yang-Feng TL, Glazer PM. Frequent spontaneous deletions at a shuttle vector locus in transgenic mice. Mutagenesis. 11: 49-56. PMID 8671715 DOI: 10.1093/Mutage/11.1.49 |
0.346 |
|
| 1996 |
Gunther EJ, Havre PA, Gasparro FP, Glazer PM. Triplex-mediated, in vitro targeting of psoralen photoadducts within the genome of a transgenic mouse. Photochemistry and Photobiology. 63: 207-12. PMID 8657733 DOI: 10.1111/J.1751-1097.1996.Tb03015.X |
0.475 |
|
| 1996 |
Wang G, Seidman MM, Glazer PM. Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair. Science (New York, N.Y.). 271: 802-5. PMID 8628995 DOI: 10.1126/Science.271.5250.802 |
0.456 |
|
| 1996 |
Golub EI, Glazer PM, Ward DC, Radding CM. Rec-A protein-mediated irreversible fixation of an oligodeoxyribonucleotide to specific site in DNA. Mutation Research. 351: 117-24. PMID 8622705 DOI: 10.1016/0027-5107(95)00212-X |
0.419 |
|
| 1996 |
Raha M, Wang G, Seidman MM, Glazer PM. Mutagenesis by third-strand-directed psoralen adducts in repair-deficient human cells: high frequency and altered spectrum in a xeroderma pigmentosum variant. Proceedings of the National Academy of Sciences of the United States of America. 93: 2941-6. PMID 8610147 DOI: 10.1073/Pnas.93.7.2941 |
0.469 |
|
| 1995 |
Wang G, Levy DD, Seidman MM, Glazer PM. Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation Molecular and Cellular Biology. 15: 1759-1768. PMID 7862165 DOI: 10.1128/Mcb.15.3.1759 |
0.48 |
|
| 1995 |
Yuan J, Yeasky TM, Rhee MC, Glazer PM. Frequent T:A-->G:C transversions in X-irradiated mouse cells. Carcinogenesis. 16: 83-8. PMID 7834808 DOI: 10.1093/Carcin/16.1.83 |
0.676 |
|
| 1995 |
Wang G, Glazer PM. Altered repair of targeted psoralen photoadducts in the context of an oligonucleotide-mediated triple helix. The Journal of Biological Chemistry. 270: 22595-601. PMID 7673252 DOI: 10.1074/Jbc.270.38.22595 |
0.506 |
|
| 1995 |
Havre PA, Yuan J, Hedrick L, Cho KR, Glazer PM. p53 inactivation by HPV16 E6 results in increased mutagenesis in human cells. Cancer Research. 55: 4420-4. PMID 7671255 |
0.629 |
|
| 1995 |
Yuan J, Yeasky TM, Havre PA, Glazer PM. Induction of p53 in mouse cells decreases mutagenesis by UV radiation. Carcinogenesis. 16: 2295-300. PMID 7586125 DOI: 10.1093/Carcin/16.10.2295 |
0.701 |
|
| 1995 |
Glazer PM, Wang G, Seidman MM, Levy DD. 63 Oligonucleotide-mediated genetic manipulation: A new approach to gene therapy International Journal of Radiation Oncology*Biology*Physics. 32: 172. DOI: 10.1016/0360-3016(95)97726-H |
0.33 |
|
| 1994 |
Gasparro FP, Havre PA, Olack GA, Gunther EJ, Glazer PM. Site-specific targeting of psoralen photoadducts with a triple helix-forming oligonucleotide: characterization of psoralen monoadduct and crosslink formation. Nucleic Acids Research. 22: 2845-52. PMID 8052539 DOI: 10.1093/Nar/22.14.2845 |
0.422 |
|
| 1994 |
Glazer P, Yuan J, Yeasky T, Rhee M. Distinctive spectrum of point mutations in x-ray treated mouse cells: Implications for DNA damage and repair pathways International Journal of Radiation Oncology*Biology*Physics. 30: 237-238. DOI: 10.1016/0360-3016(94)90771-4 |
0.666 |
|
| 1993 |
Gunther EJ, Murray NE, Glazer PM. High efficiency, restriction-deficient in vitro packaging extracts for bacteriophage lambda DNA using a new E.coli lysogen. Nucleic Acids Research. 21: 3903-4. PMID 8396240 DOI: 10.1093/Nar/21.16.3903 |
0.325 |
|
| 1993 |
Havre PA, Gunther EJ, Gasparro FP, Glazer PM. Targeted mutagenesis of DNA using triple helix-forming oligonucleotides linked to psoralen. Proceedings of the National Academy of Sciences of the United States of America. 90: 7879-83. PMID 8356097 DOI: 10.1073/Pnas.90.16.7879 |
0.503 |
|
| 1993 |
Havre PA, Glazer PM. Targeted mutagenesis of simian virus 40 DNA mediated by a triple helix-forming oligonucleotide. Journal of Virology. 67: 7324-31. PMID 8230456 DOI: 10.1128/Jvi.67.12.7324-7331.1993 |
0.522 |
|
| 1989 |
Glazer PM, Greggio NA, Metherall JE, Summers WC. UV-induced DNA-binding proteins in human cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 1163-7. PMID 2919165 DOI: 10.1073/Pnas.86.4.1163 |
0.624 |
|
| 1989 |
Summers WC, Glazer PM, Malkevich D. Lambda phage shuttle vectors for analysis of mutations in mammalian cells in culture and in transgenic mice. Mutation Research. 220: 263-8. PMID 2522589 DOI: 10.1016/0165-1110(89)90030-4 |
0.656 |
|
| 1987 |
Lacy J, Summers WP, Watson M, Glazer PM, Summers WC. Amplification and deregulation of MYC following Epstein-Barr virus infection of a human B-cell line. Proceedings of the National Academy of Sciences of the United States of America. 84: 5838-42. PMID 3039510 DOI: 10.1073/Pnas.84.16.5838 |
0.572 |
|
| 1987 |
Glazer PM, Sarkar SN, Chisholm GE, Summers WC. DNA mismatch repair detected in human cell extracts. Molecular and Cellular Biology. 7: 218-24. PMID 3031461 DOI: 10.1128/Mcb.7.1.218 |
0.638 |
|
| 1986 |
Glazer PM, Sarkar SN, Summers WC. Detection and analysis of UV-induced mutations in mammalian cell DNA using a lambda phage shuttle vector. Proceedings of the National Academy of Sciences of the United States of America. 83: 1041-4. PMID 2937054 DOI: 10.1073/Pnas.83.4.1041 |
0.685 |
|
| 1985 |
Glazer PM, Summers WC. Oncogene expression in isogenic, EBV-positive and -negative Burkitt lymphoma cell lines. Intervirology. 23: 82-9. PMID 2984143 DOI: 10.1159/000149589 |
0.581 |
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