| Year |
Citation |
Score |
| 2024 |
Granzotto A, McQuade A, Chadarevian JP, Davtyan H, Sensi SL, Parker I, Blurton-Jones M, Smith I. ER and SOCE Ca signals are not required for directed cell migration in human microglia. Biorxiv : the Preprint Server For Biology. PMID 38293075 DOI: 10.1101/2024.01.18.576126 |
0.61 |
|
| 2023 |
Eskandari-Sedighi G, Blurton-Jones M. Microglial APOE4: more is less and less is more. Molecular Neurodegeneration. 18: 99. PMID 38115077 DOI: 10.1186/s13024-023-00693-6 |
0.361 |
|
| 2023 |
Evans KT, Blake K, Longworth A, Coburn MA, Insua-Rodríguez J, McMullen TP, Nguyen QH, Ma D, Lev T, Hernandez GA, Oganyan AK, Orujyan D, Edwards RA, Pridans C, Green KN, ... ... Blurton-Jones M, et al. Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis. Nature Cell Biology. PMID 37957324 DOI: 10.1038/s41556-023-01273-y |
0.791 |
|
| 2023 |
Haukedal H, Syshøj Lorenzen S, Winther Westi E, Corsi GI, Gadekar VP, McQuade A, Davtyan H, Doncheva NT, Schmid B, Chandrasekaran A, Seemann SE, Cirera S, Blurton-Jones M, Meyer M, Gorodkin J, et al. Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3. Brain, Behavior, and Immunity. 113: 353-373. PMID 37543250 DOI: 10.1016/j.bbi.2023.07.024 |
0.747 |
|
| 2023 |
Chadarevian JP, Davtyan H, Lombroso SI, Bennett FC, Blurton-Jones M. CRISPR generation of CSF1R-G795A human microglia for robust microglia replacement in a chimeric mouse model. Star Protocols. 4: 102490. PMID 37516973 DOI: 10.1016/j.xpro.2023.102490 |
0.722 |
|
| 2023 |
Dolan MJ, Therrien M, Jereb S, Kamath T, Gazestani V, Atkeson T, Marsh SE, Goeva A, Lojek NM, Murphy S, White CM, Joung J, Liu B, Limone F, Eggan K, ... ... Blurton-Jones M, et al. Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro. Nature Immunology. PMID 37500887 DOI: 10.1038/s41590-023-01558-2 |
0.757 |
|
| 2023 |
Liu Z, Chao J, Wang C, Sun G, Roeth D, Liu W, Chen X, Li L, Tian E, Feng L, Davtyan H, Blurton-Jones M, Kalkum M, Shi Y. Astrocytic response mediated by the CLU risk allele inhibits OPC proliferation and myelination in a human iPSC model. Cell Reports. 42: 112841. PMID 37494190 DOI: 10.1016/j.celrep.2023.112841 |
0.704 |
|
| 2023 |
Kim C, Hovakimyan A, Zagorski K, Antonyan T, Petrushina I, Davtyan H, Chailyan G, Hasselmann J, Iba M, Adame A, Rockenstein E, Szabo M, Blurton-Jones M, Cribbs DH, Ghochikyan A, et al. Author Correction: Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies. Npj Vaccines. 8: 105. PMID 37460684 DOI: 10.1038/s41541-023-00703-0 |
0.681 |
|
| 2023 |
Zagorski K, King O, Hovakimyan A, Petrushina I, Antonyan T, Chailyan G, Ghazaryan M, Hyrc KL, Chadarevian JP, Davtyan H, Blurton-Jones M, Cribbs DH, Agadjanyan MG, Ghochikyan A. Novel Vaccine against Pathological Pyroglutamate-Modified Amyloid Beta for Prevention of Alzheimer's Disease. International Journal of Molecular Sciences. 24. PMID 37372944 DOI: 10.3390/ijms24129797 |
0.774 |
|
| 2023 |
McQuade A, Kang YJ, Hasselmann J, Jairaman A, Sotelo A, Coburn M, Shabestari SK, Chadarevian JP, Fote G, Tu CH, Danhash E, Silva J, Martinez E, Cotman C, Prieto GA, ... ... Blurton-Jones M, et al. Author Correction: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. Nature Communications. 14: 1194. PMID 36864071 DOI: 10.1038/s41467-023-36930-1 |
0.805 |
|
| 2022 |
Reyes-Ortiz AM, Abud EM, Burns MS, Wu J, Hernandez SJ, McClure N, Wang KQ, Schulz CJ, Miramontes R, Lau A, Michael N, Miyoshi E, Van Vactor D, Reidling JC, Blurton-Jones M, et al. Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits. Iscience. 26: 105732. PMID 36590162 DOI: 10.1016/j.isci.2022.105732 |
0.81 |
|
| 2022 |
Chadarevian JP, Lombroso SI, Peet GC, Hasselmann J, Tu C, Marzan DE, Capocchi J, Purnell FS, Nemec KM, Lahian A, Escobar A, England W, Chaluvadi S, O'Brien CA, Yaqoob F, ... ... Blurton-Jones M, et al. Engineering an inhibitor-resistant human CSF1R variant for microglia replacement. The Journal of Experimental Medicine. 220. PMID 36584406 DOI: 10.1084/jem.20220857 |
0.727 |
|
| 2022 |
Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, et al. Microglia states and nomenclature: A field at its crossroads. Neuron. 110: 3458-3483. PMID 36327895 DOI: 10.1016/j.neuron.2022.10.020 |
0.443 |
|
| 2022 |
Kiani Shabestari S, Morabito S, Danhash EP, McQuade A, Sanchez JR, Miyoshi E, Chadarevian JP, Claes C, Coburn MA, Hasselmann J, Hidalgo J, Tran KN, Martini AC, Chang Rothermich W, Pascual J, ... ... Blurton-Jones M, et al. Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice. Cell Reports. 39: 110961. PMID 35705056 DOI: 10.1016/j.celrep.2022.110961 |
0.847 |
|
| 2022 |
Zagorski K, Chailyan G, Hovakimyan A, Antonyan T, Kiani Shabestari S, Petrushina I, Davtyan H, Cribbs DH, Blurton-Jones M, Masliah E, Agadjanyan MG, Ghochikyan A. Immunogenicity of MultiTEP-Platform-Based Recombinant Protein Vaccine, PV-1950R, Targeting Three B-Cell Antigenic Determinants of Pathological α-Synuclein. International Journal of Molecular Sciences. 23. PMID 35682759 DOI: 10.3390/ijms23116080 |
0.726 |
|
| 2022 |
Jairaman A, McQuade A, Granzotto A, Kang YJ, Chadarevian JP, Gandhi S, Parker I, Smith I, Cho H, Sensi SL, Othy S, Blurton-Jones M, Cahalan MD. TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia. Elife. 11. PMID 35191835 DOI: 10.7554/eLife.73021 |
0.63 |
|
| 2022 |
Claes C, England WE, Danhash EP, Kiani Shabestari S, Jairaman A, Chadarevian JP, Hasselmann J, Tsai AP, Coburn MA, Sanchez J, Lim TE, Hidalgo JLS, Tu C, Cahalan MD, Lamb BT, ... ... Blurton-Jones M, et al. The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35142046 DOI: 10.1002/alz.12577 |
0.842 |
|
| 2022 |
You Y, Muraoka S, Jedrychowski MP, Hu J, McQuade AK, Young-Pearse T, Aslebagh R, Shaffer SA, Gygi SP, Blurton-Jones M, Poon WW, Ikezu T. Human neural cell type-specific extracellular vesicle proteome defines disease-related molecules associated with activated astrocytes in Alzheimer's disease brain. Journal of Extracellular Vesicles. 11: e12183. PMID 35029059 DOI: 10.1002/jev2.12183 |
0.729 |
|
| 2022 |
Kim C, Hovakimyan A, Zagorski K, Antonyan T, Petrushina I, Davtyan H, Chailyan G, Hasselmann J, Iba M, Adame A, Rockenstein E, Szabo M, Blurton-Jones M, Cribbs DH, Ghochikyan A, et al. Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies. Npj Vaccines. 7: 1. PMID 35013319 DOI: 10.1038/s41541-021-00424-2 |
0.73 |
|
| 2021 |
McQuade A, Blurton-Jones M. Human Induced Pluripotent Stem Cell-Derived Microglia (hiPSC-Microglia). Methods in Molecular Biology (Clifton, N.J.). PMID 34773245 DOI: 10.1007/7651_2021_429 |
0.303 |
|
| 2021 |
Chen X, Sun G, Tian E, Zhang M, Davtyan H, Beach TG, Reiman EM, Blurton-Jones M, Holtzman DM, Shi Y. Modeling Sporadic Alzheimer's Disease in Human Brain Organoids under Serum Exposure. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2101462. PMID 34337898 DOI: 10.1002/advs.202101462 |
0.794 |
|
| 2021 |
Claes C, Danhash EP, Hasselmann J, Chadarevian JP, Shabestari SK, England WE, Lim TE, Hidalgo JLS, Spitale RC, Davtyan H, Blurton-Jones M. Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer's disease. Molecular Neurodegeneration. 16: 50. PMID 34301296 DOI: 10.1186/s13024-021-00473-0 |
0.778 |
|
| 2021 |
Lall D, Lorenzini I, Mota TA, Bell S, Mahan TE, Ulrich JD, Davtyan H, Rexach JE, Muhammad AKMG, Shelest O, Landeros J, Vazquez M, Kim J, Ghaffari L, O'Rourke JG, ... ... Blurton-Jones M, et al. C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation. Neuron. PMID 34133945 DOI: 10.1016/j.neuron.2021.05.020 |
0.766 |
|
| 2020 |
McQuade A, Kang YJ, Hasselmann J, Jairaman A, Sotelo A, Coburn M, Shabestari SK, Chadarevian JP, Fote G, Tu CH, Danhash E, Silva J, Martinez E, Cotman C, Prieto GA, ... ... Blurton-Jones M, et al. Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. Nature Communications. 11: 5370. PMID 33097708 DOI: 10.1038/s41467-020-19227-5 |
0.846 |
|
| 2020 |
Liu T, Zhu B, Liu Y, Zhang X, Yin J, Li X, Jiang L, Hodges AP, Rosenthal SB, Zhou L, Yancey J, McQuade A, Blurton-Jones M, Tanzi RE, Huang TY, et al. Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE. The Journal of Experimental Medicine. 217. PMID 32941599 DOI: 10.1084/Jem.20200474 |
0.499 |
|
| 2020 |
Petrushina I, Hovakimyan A, Harahap I, Davtyan H, Antonyan T, Chailyan G, Kazarian K, Antonenko M, Jullienne A, Hamer MM, Obenaus A, King O, Zagorski K, Blurton-Jones M, Cribbs DH, et al. Characterization and preclinical evaluation of the cGMP grade DNA based vaccine, AV-1959D to enter the first-in-human clinical trials. Neurobiology of Disease. 104823. PMID 32119976 DOI: 10.1016/J.Nbd.2020.104823 |
0.775 |
|
| 2020 |
Stevens B, Blurton-Jones M, Spires-Jones TL. Decision letter: Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models Elife. DOI: 10.7554/Elife.54083.Sa1 |
0.618 |
|
| 2019 |
Davtyan H, Hovakimyan A, Kiani Shabestari S, Antonyan T, Coburn MA, Zagorski K, Chailyan G, Petrushina I, Svystun O, Danhash E, Petrovsky N, Cribbs DH, Agadjanyan MG, Blurton-Jones M, Ghochikyan A. Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice. Alzheimer's Research & Therapy. 11: 107. PMID 31847886 DOI: 10.1186/S13195-019-0556-2 |
0.839 |
|
| 2019 |
Cadete Martini A, Gomez-Arboledas A, Forner S, Rodriguez-Ortiz CJ, McQuade A, Danhash E, Phan J, Javonillo D, Ha JV, Tram M, Trujillo-Estrada L, da Cunha C, Ager RR, Davila JC, Kitazawa M, ... Blurton-Jones M, et al. Amyloid-beta impairs TOM1-mediated IL-1R1 signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 31570577 DOI: 10.1073/Pnas.1914088116 |
0.622 |
|
| 2019 |
Hasselmann J, Coburn MA, England W, Figueroa Velez DX, Kiani Shabestari S, Tu CH, McQuade A, Kolahdouzan M, Echeverria K, Claes C, Nakayama T, Azevedo R, Coufal NG, Han CZ, Cummings BJ, ... ... Blurton-Jones M, et al. Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo. Neuron. PMID 31375314 DOI: 10.1016/J.Neuron.2019.07.002 |
0.819 |
|
| 2019 |
Rojo R, Raper A, Ozdemir DD, Lefevre L, Grabert K, Wollscheid-Lengeling E, Bradford B, Caruso M, Gazova I, Sánchez A, Lisowski ZM, Alves J, Molina-Gonzalez I, Davtyan H, Lodge RJ, ... ... Blurton-Jones M, et al. Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations. Nature Communications. 10: 3215. PMID 31324781 DOI: 10.1038/S41467-019-11053-8 |
0.734 |
|
| 2019 |
Faal T, Phan DTT, Davtyan H, Scarfone VM, Varady E, Blurton-Jones M, Hughes CCW, Inlay MA. Induction of Mesoderm and Neural Crest-Derived Pericytes from Human Pluripotent Stem Cells to Study Blood-Brain Barrier Interactions. Stem Cell Reports. PMID 30745035 DOI: 10.1016/J.Stemcr.2019.01.005 |
0.775 |
|
| 2019 |
McQuade A, Blurton-Jones M. Microglia in Alzheimer's Disease: Exploring How Genetics and Phenotype Influence Risk. Journal of Molecular Biology. 431: 1805-1817. PMID 30738892 DOI: 10.1016/J.Jmb.2019.01.045 |
0.485 |
|
| 2018 |
Shukla AK, McIntyre LL, Marsh SE, Schneider CA, Hoover EM, Walsh CM, Lodoen MB, Blurton-Jones M, Inlay MA. CD11a expression distinguishes infiltrating myeloid cells from plaque-associated microglia in Alzheimer's disease. Glia. PMID 30588668 DOI: 10.1002/Glia.23575 |
0.758 |
|
| 2018 |
McQuade A, Coburn M, Tu CH, Hasselmann J, Davtyan H, Blurton-Jones M. Development and validation of a simplified method to generate human microglia from pluripotent stem cells. Molecular Neurodegeneration. 13: 67. PMID 30577865 DOI: 10.1186/S13024-018-0297-X |
0.808 |
|
| 2018 |
Nakazono T, Jun H, Blurton-Jones M, Green KN, Igarashi KM. Gamma oscillations in the entorhinal-hippocampal circuit underlying memory and dementia. Neuroscience Research. PMID 29438778 DOI: 10.1016/J.Neures.2018.02.002 |
0.573 |
|
| 2017 |
Mathur V, Burai R, Vest RT, Bonanno LN, Lehallier B, Zardeneta ME, Mistry KN, Do D, Marsh SE, Abud EM, Blurton-Jones M, Li L, Lashuel HA, Wyss-Coray T. Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation. Neuron. 96: 1290-1302.e6. PMID 29268096 DOI: 10.1016/J.Neuron.2017.11.032 |
0.778 |
|
| 2017 |
Reidling JC, Relaño-Ginés A, Holley SM, Ochaba J, Moore C, Fury B, Lau A, Tran AH, Yeung S, Salamati D, Zhu C, Hatami A, Cepeda C, Barry JA, Kamdjou T, ... ... Blurton-Jones M, et al. Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice. Stem Cell Reports. PMID 29233555 DOI: 10.1016/J.Stemcr.2017.11.005 |
0.619 |
|
| 2017 |
Davtyan H, Zagorski K, Petrushina I, Kazarian K, Goldberg NRS, Petrosyan J, Blurton-Jones M, Masliah E, Cribbs DH, Agadjanyan MG, Ghochikyan A. MultiTEP platform-based DNA vaccines for alpha-synucleinopathies: preclinical evaluation of immunogenicity and therapeutic potency. Neurobiology of Aging. PMID 28870518 DOI: 10.1016/J.Neurobiolaging.2017.08.006 |
0.74 |
|
| 2017 |
Agadjanyan MG, Zagorski K, Petrushina I, Davtyan H, Kazarian K, Antonenko M, Davis J, Bon C, Blurton-Jones M, Cribbs DH, Ghochikyan A. Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency. Molecular Neurodegeneration. 12: 33. PMID 28472993 DOI: 10.1186/S13024-017-0172-1 |
0.781 |
|
| 2017 |
Abud EM, Ramirez RN, Martinez ES, Healy LM, Nguyen CHH, Newman SA, Yeromin AV, Scarfone VM, Marsh SE, Fimbres C, Caraway CA, Fote GM, Madany AM, Agrawal A, Kayed R, ... ... Blurton-Jones M, et al. iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron. 94: 278-293.e9. PMID 28426964 DOI: 10.1016/J.Neuron.2017.03.042 |
0.843 |
|
| 2017 |
Davtyan H, Chen WW, Zagorski K, Davis J, Petrushina I, Kazarian K, Cribbs DH, Agadjanyan MG, Blurton-Jones M, Ghochikyan A. MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice. Vaccine. PMID 28320590 DOI: 10.1016/J.Vaccine.2017.03.020 |
0.83 |
|
| 2017 |
Lakatos A, Goldberg NR, Blurton-Jones M. Integrated analysis of genetic, behavioral, and biochemical data implicates neural stem cell-induced changes in immunity, neurotransmission and mitochondrial function in Dementia with Lewy Body mice. Acta Neuropathologica Communications. 5: 21. PMID 28283027 DOI: 10.1186/S40478-017-0421-0 |
0.782 |
|
| 2017 |
Goldberg NR, Marsh SE, Ochaba J, Shelley BC, Davtyan H, Thompson LM, Steffan JS, Svendsen CN, Blurton-Jones M. Human Neural Progenitor Transplantation Rescues Behavior and Reduces α-Synuclein in a Transgenic Model of Dementia with Lewy Bodies. Stem Cells Translational Medicine. PMID 28225193 DOI: 10.1002/Sctm.16-0362 |
0.808 |
|
| 2017 |
Marsh SE, Blurton-Jones M. Neural stem cell therapy for neurodegenerative disorders: The role of neurotrophic support. Neurochemistry International. PMID 28219641 DOI: 10.1016/J.Neuint.2017.02.006 |
0.709 |
|
| 2017 |
Marsh SE, Yeung ST, Torres M, Lau L, Davis JL, Monuki ES, Poon WW, Blurton-Jones M. HuCNS-SC Human NSCs Fail to Differentiate, Form Ectopic Clusters, and Provide No Cognitive Benefits in a Transgenic Model of Alzheimer's Disease. Stem Cell Reports. 8: 235-248. PMID 28199828 DOI: 10.1016/J.Stemcr.2016.12.019 |
0.832 |
|
| 2017 |
Monuki ES, Anderson AJ, Blurton-Jones M, Cummings BJ. Response to StemCells Inc. Stem Cell Reports. 8: 195-197. PMID 28199827 DOI: 10.1016/J.Stemcr.2017.02.002 |
0.614 |
|
| 2016 |
Chen W, Abud EA, Yeung ST, Lakatos A, Nassi T, Wang J, Blum D, Buée L, Poon WW, Blurton-Jones M. Increased tauopathy drives microglia-mediated clearance of beta-amyloid. Acta Neuropathologica Communications. 4: 63. PMID 27339073 DOI: 10.1186/S40478-016-0336-1 |
0.825 |
|
| 2016 |
Spangenberg EE, Lee RJ, Najafi AR, Rice RA, Elmore MR, Blurton-Jones M, West BL, Green KN. Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology. Brain : a Journal of Neurology. PMID 26921617 DOI: 10.1093/Brain/Aww016 |
0.658 |
|
| 2016 |
Marsh SE, Abud EM, Lakatos A, Karimzadeh A, Yeung ST, Davtyan H, Fote GM, Lau L, Weinger JG, Lane TE, Inlay MA, Poon WW, Blurton-Jones M. The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884167 DOI: 10.1073/Pnas.1525466113 |
0.815 |
|
| 2016 |
Marsh SE, Karimzadeh A, Abud EM, Lakatos A, Yeung ST, Davtyan H, Fote G, Lau L, Weinger JG, Lane TE, Poon WW, Inlay MA, Blurton-Jones M. P1-158: The Adaptive Immune System Critically Regulates Alzheimer’s Disease Pathogenesis by Modulating Microglial Function Alzheimer's & Dementia. 12: P463-P464. DOI: 10.1016/J.Jalz.2016.06.906 |
0.77 |
|
| 2016 |
Ghochikyan A, Zagorski K, Kazarian K, Davtyan H, Petrushina I, Davis J, Chen WW, Antonenko M, Blurton-Jones M, Cribbs DH, Agadjanyan MG. O2-13-02: Humanized Mab, Armanezumab Targeting N-Terminus of Pathological Tau: Characterization and Therapeutic Potency Alzheimer's & Dementia. 12: P260-P260. DOI: 10.1016/J.Jalz.2016.06.467 |
0.729 |
|
| 2016 |
Davtyan H, Chen WW, Zagorski K, Davis J, Petrushina I, Cribbs DH, Agadjanyan MG, Blurton-Jones M, Ghochikyan A. P4-037: The First Multitep-Based DNA Vaccine Targeting n-Terminus of Pathological TAU Induces Strong Immune Responses and Reduces TAU Pathology in TAU Transgenic Mice Alzheimer's & Dementia. 12: P1029-P1029. DOI: 10.1016/J.Jalz.2016.06.2126 |
0.808 |
|
| 2015 |
Goldberg NR, Caesar J, Park A, Sedgh S, Finogenov G, Masliah E, Davis J, Blurton-Jones M. Neural Stem Cells Rescue Cognitive and Motor Dysfunction in a Transgenic Model of Dementia with Lewy Bodies through a BDNF-Dependent Mechanism. Stem Cell Reports. PMID 26489892 DOI: 10.1016/J.Stemcr.2015.09.008 |
0.776 |
|
| 2015 |
Ager RR, Davis JL, Agazaryan A, Benavente F, Poon WW, LaFerla FM, Blurton-Jones M. Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss. Hippocampus. 25: 813-26. PMID 25530343 DOI: 10.1002/Hipo.22405 |
0.793 |
|
| 2014 |
Blurton-Jones M, Spencer B, Michael S, Castello NA, Agazaryan AA, Davis JL, Müller FJ, Loring JF, Masliah E, LaFerla FM. Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models. Stem Cell Research & Therapy. 5: 46. PMID 25022790 DOI: 10.1186/Scrt440 |
0.851 |
|
| 2013 |
Rodriguez-Ortiz CJ, Hoshino H, Cheng D, Liu-Yescevitz L, Blurton-Jones M, Wolozin B, LaFerla FM, Kitazawa M. Neuronal-specific overexpression of a mutant valosin-containing protein associated with IBMPFD promotes aberrant ubiquitin and TDP-43 accumulation and cognitive dysfunction in transgenic mice. The American Journal of Pathology. 183: 504-15. PMID 23747512 DOI: 10.1016/J.Ajpath.2013.04.014 |
0.606 |
|
| 2013 |
Lakatos A, Coskun P, Ho J, Smith I, Potkin S, Saykin A, Blurton-Jones M. P2-012: Early detection of Alzheimer's disease: Probing mitochondrial function in the periphery Alzheimer's & Dementia. 9: P349-P349. DOI: 10.1016/J.Jalz.2013.05.654 |
0.345 |
|
| 2012 |
Chabrier MA, Blurton-Jones M, Agazaryan AA, Nerhus JL, Martinez-Coria H, LaFerla FM. Soluble aβ promotes wild-type tau pathology in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17345-50. PMID 23197725 DOI: 10.1523/Jneurosci.0172-12.2012 |
0.843 |
|
| 2012 |
Chen WW, Blurton-Jones M. Concise review: Can stem cells be used to treat or model Alzheimer's disease? Stem Cells (Dayton, Ohio). 30: 2612-8. PMID 22997040 DOI: 10.1002/Stem.1240 |
0.835 |
|
| 2012 |
Walls KC, Coskun P, Gallegos-Perez JL, Zadourian N, Freude K, Rasool S, Blurton-Jones M, Green KN, LaFerla FM. Swedish Alzheimer mutation induces mitochondrial dysfunction mediated by HSP60 mislocalization of amyloid precursor protein (APP) and beta-amyloid. The Journal of Biological Chemistry. 287: 30317-27. PMID 22753410 DOI: 10.1074/Jbc.M112.365890 |
0.702 |
|
| 2012 |
Marsh SE, Blurton-Jones M. Examining the mechanisms that link β-amyloid and α-synuclein pathologies. Alzheimer's Research & Therapy. 4: 11. PMID 22546279 DOI: 10.1186/Alzrt109 |
0.75 |
|
| 2012 |
Blurton-Jones M, Ager R, Nerhus J, Agazaryan A, Huhn S, Capela A, LaFerla F. P3-345: Restoration of memory in mouse models of Alzheimer's disease and neuronal loss: A new paradigm using human neural stem cell therapy Alzheimer's & Dementia. 8: P577-P578. DOI: 10.1016/J.Jalz.2012.05.1569 |
0.596 |
|
| 2012 |
Chabrier M, Blurton-Jones M, Agazaryan A, Nerhus J, LaFerla F, Coria HM. Soluble Aβ promotes wild-type tau pathology in vivo Alzheimers & Dementia. 8: 475. DOI: 10.1016/J.Jalz.2012.05.1279 |
0.819 |
|
| 2012 |
Ager R, Blurton-Jones M, Davis J, Agazaryan A, LaFerla F. P2-391: Human neural stem cell transplantation results in memory improvement in a 3xTg Alzheimer's disease model mice Alzheimer's & Dementia. 8: P399-P400. DOI: 10.1016/J.Jalz.2012.05.1101 |
0.611 |
|
| 2012 |
Blurton-Jones M, Nerhus JL, LaFerla FM. Transplanting Stem Cells into the Brain Human Stem Cell Manual. 529-542. DOI: 10.1016/B978-0-12-385473-5.00034-5 |
0.482 |
|
| 2011 |
Freude KK, Penjwini M, Davis JL, LaFerla FM, Blurton-Jones M. Soluble amyloid precursor protein induces rapid neural differentiation of human embryonic stem cells. The Journal of Biological Chemistry. 286: 24264-74. PMID 21606494 DOI: 10.1074/Jbc.M111.227421 |
0.609 |
|
| 2011 |
Poon WW, Blurton-Jones M, Tu CH, Feinberg LM, Chabrier MA, Harris JW, Jeon NL, Cotman CW. β-Amyloid impairs axonal BDNF retrograde trafficking. Neurobiology of Aging. 32: 821-33. PMID 19540623 DOI: 10.1016/J.Neurobiolaging.2009.05.012 |
0.783 |
|
| 2011 |
Lopes JP, Blurton-Jones M, Yamasaki TR, Agostinho P, LaFerla FM. Activation of cell cycle proteins in transgenic mice in response to neuronal loss but not aß and tau pathology Advances in Alzheimer's Disease. 1: 139-148. DOI: 10.3233/978-1-60750-733-8-139 |
0.807 |
|
| 2010 |
Clinton LK, Blurton-Jones M, Myczek K, Trojanowski JQ, LaFerla FM. Synergistic Interactions between Abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 7281-9. PMID 20505094 DOI: 10.1523/Jneurosci.0490-10.2010 |
0.823 |
|
| 2010 |
Koike MA, Green KN, Blurton-Jones M, Laferla FM. Oligemic hypoperfusion differentially affects tau and amyloid-{beta}. The American Journal of Pathology. 177: 300-10. PMID 20472896 DOI: 10.2353/Ajpath.2010.090750 |
0.721 |
|
| 2010 |
Blurton-Jones M, Kitazawa M, Martinez-Coria H, Castello NA, Muller F, Loring JF, Poon WW, Green K, LaFerla FM. O1-04-01: Using neural stem cells to promote plasticity and improve cognition in transgenic AD mice Alzheimer's & Dementia. 6: S76-S76. DOI: 10.1016/J.Jalz.2010.05.225 |
0.812 |
|
| 2009 |
Blurton-Jones M, Kitazawa M, Martinez-Coria H, Castello NA, Müller FJ, Loring JF, Yamasaki TR, Poon WW, Green KN, LaFerla FM. Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 106: 13594-9. PMID 19633196 DOI: 10.1073/Pnas.0901402106 |
0.828 |
|
| 2009 |
McAlpine FE, Lee JK, Harms AS, Ruhn KA, Blurton-Jones M, Hong J, Das P, Golde TE, LaFerla FM, Oddo S, Blesch A, Tansey MG. Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology. Neurobiology of Disease. 34: 163-77. PMID 19320056 DOI: 10.1016/J.Nbd.2009.01.006 |
0.813 |
|
| 2009 |
Lopes JP, Blurton-Jones M, Yamasaki TR, Agostinho P, LaFerla FM. Activation of cell cycle proteins in transgenic mice in response to neuronal loss but not amyloid-beta and tau pathology. Journal of Alzheimer's Disease : Jad. 16: 541-9. PMID 19276549 DOI: 10.3233/Jad-2009-0993 |
0.839 |
|
| 2008 |
Tseng BP, Green KN, Chan JL, Blurton-Jones M, LaFerla FM. Abeta inhibits the proteasome and enhances amyloid and tau accumulation. Neurobiology of Aging. 29: 1607-18. PMID 17544172 DOI: 10.1016/J.Neurobiolaging.2007.04.014 |
0.832 |
|
| 2007 |
Yamasaki TR, Blurton-Jones M, Morrissette DA, Kitazawa M, Oddo S, LaFerla FM. Neural stem cells improve memory in an inducible mouse model of neuronal loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11925-33. PMID 17978032 DOI: 10.1523/Jneurosci.1627-07.2007 |
0.795 |
|
| 2007 |
Parachikova A, Agadjanyan MG, Cribbs DH, Blurton-Jones M, Perreau V, Rogers J, Beach TG, Cotman CW. Inflammatory changes parallel the early stages of Alzheimer disease. Neurobiology of Aging. 28: 1821-33. PMID 17052803 DOI: 10.1016/J.Neurobiolaging.2006.08.014 |
0.83 |
|
| 2006 |
Blurton-Jones M, Laferla FM. Pathways by which Abeta facilitates tau pathology. Current Alzheimer Research. 3: 437-48. PMID 17168643 DOI: 10.2174/156720506779025242 |
0.625 |
|
| 2006 |
Blurton-Jones M, Tuszynski MH. Estradiol-induced modulation of estrogen receptor-beta and GABA within the adult neocortex: a potential transsynaptic mechanism for estrogen modulation of BDNF. The Journal of Comparative Neurology. 499: 603-12. PMID 17029253 DOI: 10.1002/Cne.21122 |
0.527 |
|
| 2005 |
Taylor AM, Blurton-Jones M, Rhee SW, Cribbs DH, Cotman CW, Jeon NL. A microfluidic culture platform for CNS axonal injury, regeneration and transport. Nature Methods. 2: 599-605. PMID 16094385 DOI: 10.1038/Nmeth777 |
0.537 |
|
| 2005 |
Cotman CW, Poon WW, Rissman RA, Blurton-Jones M. The role of caspase cleavage of tau in Alzheimer disease neuropathology. Journal of Neuropathology and Experimental Neurology. 64: 104-12. PMID 15751224 DOI: 10.1093/Jnen/64.2.104 |
0.81 |
|
| 2004 |
Cribbs DH, Poon WW, Rissman RA, Blurton-Jones M. Caspase-mediated degeneration in Alzheimer's disease. The American Journal of Pathology. 165: 353-5. PMID 15277211 DOI: 10.1016/S0002-9440(10)63302-0 |
0.785 |
|
| 2004 |
Rissman RA, Poon WW, Blurton-Jones M, Oddo S, Torp R, Vitek MP, LaFerla FM, Rohn TT, Cotman CW. Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. The Journal of Clinical Investigation. 114: 121-30. PMID 15232619 DOI: 10.1172/Jci20640 |
0.839 |
|
| 2004 |
Blurton-Jones M, Kuan PN, Tuszynski MH. Anatomical evidence for transsynaptic influences of estrogen on brain-derived neurotrophic factor expression. The Journal of Comparative Neurology. 468: 347-60. PMID 14681930 DOI: 10.1002/Cne.10989 |
0.54 |
|
| 2002 |
Blurton-Jones M, Tuszynski MH. Estrogen receptor-beta colocalizes extensively with parvalbumin-labeled inhibitory neurons in the cortex, amygdala, basal forebrain, and hippocampal formation of intact and ovariectomized adult rats. The Journal of Comparative Neurology. 452: 276-87. PMID 12353223 DOI: 10.1002/Cne.10393 |
0.515 |
|
| 2001 |
Blurton-Jones M, Tuszynski MH. Reactive astrocytes express estrogen receptors in the injured primate brain. The Journal of Comparative Neurology. 433: 115-23. PMID 11283953 DOI: 10.1002/Cne.1129 |
0.536 |
|
| 1999 |
Blurton-Jones MM, Roberts JA, Tuszynski MH. Estrogen receptor immunoreactivity in the adult primate brain: neuronal distribution and association with p75, trkA, and choline acetyltransferase. The Journal of Comparative Neurology. 405: 529-42. PMID 10098943 DOI: 10.1002/(Sici)1096-9861(19990322)405:4<529::Aid-Cne6>3.0.Co;2-Y |
0.541 |
|
| Show low-probability matches. |