Wei Liu, Ph.D. - Publications

Affiliations: 
2002-2008 Biophysics Ohio State University, Columbus, Columbus, OH 
 2006-2007 Chemical and Environmental Sciences University of Limerick, Limerick, Ireland 
 2007-2014 Integrative Molecular and Computational Biology Scripps Research Institute, La Jolla, La Jolla, CA, United States 
 2015- Biodesign Institute Arizona State University, Tempe, AZ, United States 

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Chen Y, Zhang J, Weng Y, Xu Y, Lu W, Liu W, Liu M, Hua T, Song G. Cryo-EM structure of the human adenosine A receptor-G signaling complex. Science Advances. 8: eadd3709. PMID 36563137 DOI: 10.1126/sciadv.add3709  0.457
2022 Qian Y, Wang J, Yang L, Liu Y, Wang L, Liu W, Lin Y, Yang H, Ma L, Ye S, Wu S, Qiao A. Activation and signaling mechanism revealed by GPR119-G complex structures. Nature Communications. 13: 7033. PMID 36396650 DOI: 10.1038/s41467-022-34696-6  0.464
2022 Lyapina E, Marin E, Gusach A, Orekhov P, Gerasimov A, Luginina A, Vakhrameev D, Ergasheva M, Kovaleva M, Khusainov G, Khorn P, Shevtsov M, Kovalev K, Bukhdruker S, Okhrimenko I, ... ... Liu W, et al. Structural basis for receptor selectivity and inverse agonism in S1P receptors. Nature Communications. 13: 4736. PMID 35961984 DOI: 10.1038/s41467-022-32447-1  0.426
2022 Su M, Paknejad N, Zhu L, Wang J, Do HN, Miao Y, Liu W, Hite RK, Huang XY. Structures of β-adrenergic receptor in complex with Gs and ligands of different efficacies. Nature Communications. 13: 4095. PMID 35835792 DOI: 10.1038/s41467-022-31823-1  0.351
2022 Zhang M, Qin Q, Zhang S, Liu W, Meng H, Xu M, Huang X, Lin X, Lin M, Herman P, Hyder F, Stevens RC, Wang Z, Li B, Thompson GJ. Aerobic glycolysis imaging of epileptic foci during the inter-ictal period. Ebiomedicine. 79: 104004. PMID 35436726 DOI: 10.1016/j.ebiom.2022.104004  0.324
2022 Liu S, Paknejad N, Zhu L, Kihara Y, Ray M, Chun J, Liu W, Hite RK, Huang XY. Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nature Communications. 13: 731. PMID 35136060 DOI: 10.1038/s41467-022-28417-2  0.318
2021 Liu H, Deepak RNVK, Shiriaeva A, Gati C, Batyuk A, Hu H, Weierstall U, Liu W, Wang L, Cherezov V, Fan H, Zhang C. Molecular basis for lipid recognition by the prostaglandin D receptor CRTH2. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34341104 DOI: 10.1073/pnas.2102813118  0.38
2021 Olson TL, Zhang S, Labban D, Kaschner E, Aceves M, Iyer S, Meza D, Zook JD, Chun E, Craciunescu FM, Liu W, Shi CX, Stewart AK, Hansen DT, Meurice N, et al. Protein expression and purification of G-protein coupled receptor kinase 6 (GRK6), toward structure-based drug design and discovery for multiple myeloma. Protein Expression and Purification. 105890. PMID 33971243 DOI: 10.1016/j.pep.2021.105890  0.787
2021 Geiger J, Sexton R, Al-Sahouri Z, Lee MY, Chun E, Harikumar KG, Miller LJ, Beckstein O, Liu W. Evidence that specific interactions play a role in the cholesterol sensitivity of G protein-coupled receptors. Biochimica Et Biophysica Acta. Biomembranes. 183557. PMID 33444621 DOI: 10.1016/j.bbamem.2021.183557  0.799
2020 Lee MY, Geiger J, Ishchenko A, Han GW, Barty A, White TA, Gati C, Batyuk A, Hunter MS, Aquila A, Boutet S, Weierstall U, Cherezov V, Liu W. Harnessing the power of an X-ray laser for serial crystallography of membrane proteins crystallized in lipidic cubic phase. Iucrj. 7: 976-984. PMID 33209312 DOI: 10.1107/S2052252520012701  0.321
2020 Zhu L, Chen X, Abola EE, Jing L, Liu W. Serial Crystallography for Structure-Based Drug Discovery. Trends in Pharmacological Sciences. PMID 32950259 DOI: 10.1016/J.Tips.2020.08.009  0.382
2020 Su M, Zhu L, Zhang Y, Paknejad N, Dey R, Huang J, Lee MY, Williams D, Jordan KD, Eng ET, Ernst OP, Meyerson JR, Hite RK, Walz T, Liu W, et al. Structural Basis of the Activation of Heterotrimeric Gs-Protein by Isoproterenol-Bound β-Adrenergic Receptor. Molecular Cell. PMID 32818430 DOI: 10.1016/J.Molcel.2020.08.001  0.355
2020 Zhu L, Bu G, Jing L, Shi D, Lee MY, Gonen T, Liu W, Nannenga BL. Structure Determination from Lipidic Cubic Phase Embedded Microcrystals by MicroED. Structure (London, England : 1993). PMID 32735770 DOI: 10.1016/J.Str.2020.07.006  0.404
2020 Chen F, Chen X, Jiang F, Leng F, Liu W, Gui Y, Yu J. Computational analysis of androgen receptor (AR) variants to decipher the relationship between protein stability and related-diseases. Scientific Reports. 10: 12101. PMID 32694570 DOI: 10.1038/S41598-020-68731-7  0.311
2020 Zook J, Shekhar M, Hansen D, Conrad C, Grant T, Gupta C, White T, Barty A, Basu S, Zhao Y, Zatsepin N, Ishchenko A, Batyuk A, Gati C, Li C, ... ... Liu W, et al. XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia. Structure (London, England : 1993). PMID 32142641 DOI: 10.1016/J.Str.2020.02.005  0.347
2019 Ishchenko A, Stauch B, Han GW, Batyuk A, Shiriaeva A, Li C, Zatsepin N, Weierstall U, Liu W, Nango E, Nakane T, Tanaka R, Tono K, Joti Y, Iwata S, et al. Toward G protein-coupled receptor structure-based drug design using X-ray lasers. Iucrj. 6: 1106-1119. PMID 31709066 DOI: 10.1107/s2052252519013137  0.545
2019 Luginina A, Gusach A, Marin E, Mishin A, Brouillette R, Popov P, Shiriaeva A, Besserer-Offroy É, Longpré JM, Lyapina E, Ishchenko A, Patel N, Polovinkin V, Safronova N, Bogorodskiy A, ... ... Liu W, et al. Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs. Science Advances. 5: eaax2518. PMID 31633023 DOI: 10.1126/Sciadv.Aax2518  0.702
2019 Duan J, Li J, Chen GL, Ge Y, Liu J, Xie K, Peng X, Zhou W, Zhong J, Zhang Y, Xu J, Xue C, Liang B, Zhu L, Liu W, et al. Cryo-EM structure of TRPC5 at 2.8-Å resolution reveals unique and conserved structural elements essential for channel function. Science Advances. 5: eaaw7935. PMID 31355338 DOI: 10.1126/Sciadv.Aaw7935  0.384
2019 Li J, Liu H, Raval MH, Wan J, Yengo CM, Liu W, Zhang M. Structure of the MORN4/Myo3a Tail Complex Reveals MORN Repeats as Protein Binding Modules. Structure (London, England : 1993). PMID 31279628 DOI: 10.1016/J.Str.2019.06.004  0.391
2019 Martin-Garcia JM, Zhu L, Mendez D, Lee MY, Chun E, Li C, Hu H, Subramanian G, Kissick D, Ogata C, Henning R, Ishchenko A, Dobson Z, Zhang S, Weierstall U, ... ... Liu W, et al. High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source. Iucrj. 6: 412-425. PMID 31098022 DOI: 10.2210/Pdb6Mh8/Pdb  0.75
2019 Stauch B, Johansson LC, McCorvy JD, Patel N, Han GW, Huang XP, Gati C, Batyuk A, Slocum ST, Ishchenko A, Brehm W, White TA, Michaelian N, Madsen C, Zhu L, ... ... Liu W, et al. Publisher Correction: Structural basis of ligand recognition at the human MT melatonin receptor. Nature. PMID 31048811 DOI: 10.1038/S41586-019-1209-0  0.691
2019 Yang Q, Liu H, Li Z, Wang Y, Liu W. Purification and mutagenesis studies of TANC1 ankyrin repeats domain provide clues to understand mis-sense variants from diseases. Biochemical and Biophysical Research Communications. PMID 31040020 DOI: 10.1016/J.Bbrc.2019.04.151  0.325
2019 Stauch B, Johansson LC, McCorvy JD, Patel N, Han GW, Huang XP, Gati C, Batyuk A, Slocum ST, Ishchenko A, Brehm W, White TA, Michaelian N, Madsen C, Zhu L, ... ... Liu W, et al. Structural basis of ligand recognition at the human MT melatonin receptor. Nature. PMID 31019306 DOI: 10.1038/S41586-019-1141-3  0.758
2019 Johansson LC, Stauch B, McCorvy JD, Han GW, Patel N, Huang XP, Batyuk A, Gati C, Slocum ST, Li C, Grandner JM, Hao S, Olsen RHJ, Tribo AR, Zaare S, ... ... Liu W, et al. XFEL structures of the human MT melatonin receptor reveal the basis of subtype selectivity. Nature. PMID 31019305 DOI: 10.1038/s41586-019-1144-0  0.781
2018 Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, et al. Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E receptor. Nature Chemical Biology. PMID 30573766 DOI: 10.1038/S41589-018-0214-1  0.777
2018 Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, et al. Crystal structure of misoprostol bound to the labor inducer prostaglandin E receptor. Nature Chemical Biology. PMID 30510194 DOI: 10.1038/S41589-018-0160-Y  0.827
2018 Li Z, Liu H, Li J, Yang Q, Feng Z, Li Y, Yang H, Yu C, Wan J, Liu W, Zhang M. Homer Tetramer Promotes Actin Bundling Activity of Drebrin. Structure (London, England : 1993). PMID 30503778 DOI: 10.1016/J.Str.2018.10.011  0.322
2018 Lan Z, Lee MY, Chun E, Liu B, Liu W. Overview of Biochemical Assays in Lipidic Cubic Phase. Trends in Biochemical Sciences. PMID 30243833 DOI: 10.1016/J.Tibs.2018.08.008  0.759
2018 Lan TY, Wierman JL, Tate MW, Philipp HT, Martin-Garcia JM, Zhu L, Kissick D, Fromme P, Fischetti RF, Liu W, Elser V, Gruner SM. Solving protein structure from sparse serial microcrystal diffraction data at a storage-ring synchrotron source. Iucrj. 5: 548-558. PMID 30224958 DOI: 10.1107/S205225251800903X  0.357
2018 Wang Y, Shang Y, Li J, Chen W, Li G, Wan J, Liu W, Zhang M. Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions. Elife. 7. PMID 29749928 DOI: 10.7554/Elife.35677  0.419
2018 Sun Z, Zheng Y, Liu W. Identification and characterization of a novel calmodulin binding site in Drosophila TRP C-terminus. Biochemical and Biophysical Research Communications. PMID 29730291 DOI: 10.1016/J.Bbrc.2018.05.007  0.31
2018 Li Q, Yang W, Wang Y, Liu W. Biochemical and Structural Studies of the Interaction between ARAP1 and CIN85. Biochemistry. PMID 29589748 DOI: 10.1021/Acs.Biochem.8B00057  0.376
2018 Ye F, Huang Y, Li J, Ma Y, Xie C, Liu Z, Deng X, Wan J, Xue T, Liu W, Zhang M. Author response: An unexpected INAD PDZ tandem-mediated plcβ binding in Drosophila photo receptors Elife. DOI: 10.7554/Elife.41848.036  0.414
2018 Wang Y, Shang Y, Li J, Chen W, Li G, Wan J, Liu W, Zhang M. Author response: Specific Eph receptor-cytoplasmic effector signaling mediated by SAM–SAM domain interactions Elife. DOI: 10.7554/Elife.35677.030  0.372
2018 Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, et al. Crystal structure of EP3 receptor bound to misoprostol-FA Nature Chemical Biology. DOI: 10.2210/Pdb6M9T/Pdb  0.812
2018 Ye F, Huang Y, Li J, Ma Y, Xie C, Liu Z, Deng X, Wan J, Xue T, Liu W, Zhang M. An unexpected INAD PDZ tandem-mediated plc beta binding inDrosophilaphoto receptors. Elife. 7. DOI: 10.2210/Pdb6Ire/Pdb  0.373
2017 Kung PP, Bingham P, Brooun A, Collins MR, Deng YL, Dinh DM, Fan C, Gajiwala KS, Grantner R, Gukasyan HJ, Hu W, Huang B, Kania RS, Kephart SE, Krivacic CT, ... ... Liu W, et al. Optimization of orally bioavailable enhancer of zeste homolog 2 (EZH2) inhibitors using ligand and property-based design strategies: Identification of development candidate (R)-5,8-dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2H)-one (PF-06821497). Journal of Medicinal Chemistry. PMID 29211475 DOI: 10.1021/Acs.Jmedchem.7B01375  0.322
2017 Yao N, Li J, Liu H, Wan J, Liu W, Zhang M. The Structure of the ZMYND8/Drebrin Complex Suggests a Cytoplasmic Sequestering Mechanism of ZMYND8 by Drebrin. Structure (London, England : 1993). PMID 28966017 DOI: 10.1016/J.Str.2017.08.014  0.359
2017 Martin-Garcia JM, Conrad CE, Nelson G, Stander N, Zatsepin NA, Zook J, Zhu L, Geiger J, Chun E, Kissick D, Hilgart MC, Ogata C, Ishchenko A, Nagaratnam N, Roy-Chowdhury S, ... Liu W, et al. Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation. Iucrj. 4: 439-454. PMID 28875031 DOI: 10.1107/S205225251700570X  0.783
2017 Yang W, Padkjær SB, Wang J, Sun Z, Shan B, Yang L, Chen H, Kang L, Madsen D, Li X, Shen C, Yu B, Zhu H, Chao TY, Cao Z, ... ... Liu W, et al. Construction of a versatile expression library for all human single-pass transmembrane proteins for receptor pairings by high throughput screening. Journal of Biotechnology. PMID 28867483 DOI: 10.1016/J.Jbiotec.2017.08.023  0.315
2017 Ishchenko A, Wacker D, Kapoor M, Zhang A, Han GW, Basu S, Patel N, Messerschmidt M, Weierstall U, Liu W, Katritch V, Roth BL, Stevens RC, Cherezov V. Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716900 DOI: 10.1073/Pnas.1700891114  0.83
2017 Zhang H, Qiao A, Yang D, Yang L, Dai A, de Graaf C, Reedtz-Runge S, Dharmarajan V, Zhang H, Han GW, Grant TD, Sierra RG, Weierstall U, Nelson G, Liu W, et al. Structure of the full-length glucagon class B G-protein-coupled receptor. Nature. PMID 28514451 DOI: 10.1038/Nature22363  0.795
2017 Zhang H, Han GW, Batyuk A, Ishchenko A, White KL, Patel N, Sadybekov A, Zamlynny B, Rudd MT, Hollenstein K, Tolstikova A, White TA, Hunter MS, Weierstall U, Liu W, et al. Structural basis for selectivity and diversity in angiotensin II receptors. Nature. PMID 28379944 DOI: 10.1038/Nature22035  0.818
2017 Brautigam CA, Deka RK, Liu WZ, Tomchick DR, Norgard MV. Functional clues from the crystal structure of an orphan periplasmic ligand-binding protein from Treponema pallidum. Protein Science : a Publication of the Protein Society. PMID 28168761 DOI: 10.1002/Pro.3133  0.31
2016 Xiang J, Chun E, Liu C, Jing L, Al-Sahouri Z, Zhu L, Liu W. Successful Strategies to Determine High-Resolution Structures of GPCRs. Trends in Pharmacological Sciences. PMID 27726881 DOI: 10.1016/J.Tips.2016.09.009  0.822
2016 Ishchenko A, Cherezov V, Liu W. Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography. Journal of Visualized Experiments : Jove. PMID 27683972 DOI: 10.1016/J.Bpj.2015.11.383  0.43
2016 Batyuk A, Galli L, Ishchenko A, Han GW, Gati C, Popov PA, Lee MY, Stauch B, White TA, Barty A, Aquila A, Hunter MS, Liang M, Boutet S, Pu M, ... Liu W, et al. Native phasing of x-ray free-electron laser data for a G protein-coupled receptor. Science Advances. 2: e1600292. PMID 27679816 DOI: 10.1126/Sciadv.1600292  0.73
2016 Zhu L, Weierstall U, Cherezov V, Liu W. Serial Femtosecond Crystallography of Membrane Proteins. Advances in Experimental Medicine and Biology. 922: 151-60. PMID 27553241 DOI: 10.1007/978-3-319-35072-1_11  0.448
2016 White TA, Barty A, Liu W, Ishchenko A, Zhang H, Gati C, Zatsepin NA, Basu S, Oberthür D, Metz M, Beyerlein KR, Yoon CH, Yefanov OM, James D, Wang D, et al. Serial femtosecond crystallography datasets from G protein-coupled receptors. Scientific Data. 3: 160057. PMID 27479354 DOI: 10.1038/Sdata.2016.57  0.511
2016 Wang Y, Li Q, Zheng Y, Li G, Liu W. Systematic biochemical characterization of the SAM domains in Eph receptor family from Mus Musculus. Biochemical and Biophysical Research Communications. PMID 27086853 DOI: 10.1016/J.Bbrc.2016.04.059  0.449
2016 Zhou XE, Gao X, Barty A, Kang Y, He Y, Liu W, Ishchenko A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Suino-Powell KM, Boutet S, Williams GJ, et al. X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex. Scientific Data. 3: 160021. PMID 27070998 DOI: 10.1038/Sdata.2016.21  0.617
2016 Ye F, Liu W, Shang Y, Zhang M. An Exquisitely Specific PDZ/Target Recognition Revealed by the Structure of INAD PDZ3 in Complex with TRP Channel Tail. Structure (London, England : 1993). PMID 26853938 DOI: 10.1016/J.Str.2015.12.013  0.367
2015 Li D, Stansfeld PJ, Sansom MS, Keogh A, Vogeley L, Howe N, Lyons JA, Aragao D, Fromme P, Fromme R, Basu S, Grotjohann I, Kupitz C, Rendek K, Weierstall U, ... Liu W, et al. Ternary structure reveals mechanism of a membrane diacylglycerol kinase. Nature Communications. 6: 10140. PMID 26673816 DOI: 10.1038/Ncomms10140  0.341
2015 Zha Z, Zhao X, Liu W, Zhang M, Tang B, Wu B, Qu F, Chen X, Wu X, Cao L, Guo H. Preparation and Identification of a Monoclonal Antibody Against Cystatin C. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 34: 334-340. PMID 26492621 DOI: 10.1089/mab.2015.0003  0.334
2015 Fromme R, Ishchenko A, Metz M, Chowdhury SR, Basu S, Boutet S, Fromme P, White TA, Barty A, Spence JC, Weierstall U, Liu W, Cherezov V. Serial femtosecond crystallography of soluble proteins in lipidic cubic phase. Iucrj. 2: 545-51. PMID 26306196 DOI: 10.1107/S2052252515013160  0.382
2015 Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, et al. Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature. PMID 26200343 DOI: 10.1038/Nature14656  0.748
2015 Yuan ZJ, Zhou WW, Liu W, Wu BP, Zhao J, Wu W, He Y, Yang S, Su J, Luo Y. Association of GSTP1 and RRM1 Polymorphisms with the Response and Toxicity of Gemcitabine-cisplatin Combination Chemotherapy in Chinese Patients with Non-small Cell Lung Cancer. Asian Pacific Journal of Cancer Prevention : Apjcp. 16: 4347-51. PMID 26028097  0.32
2015 Rajan S, Choi M, Nguyen QT, Ye H, Liu W, Toh HT, Kang C, Kamariah N, Li C, Huang H, White C, Baek K, Grüber G, Yoon HS. Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport. Scientific Reports. 5: 10609. PMID 26023881 DOI: 10.1038/Srep10609  0.321
2015 Zhang H, Unal H, Gati C, Han GW, Liu W, Zatsepin NA, James D, Wang D, Nelson G, Weierstall U, Sawaya MR, Xu Q, Messerschmidt M, Williams GJ, Boutet S, et al. Structure of the Angiotensin receptor revealed by serial femtosecond crystallography. Cell. 161: 833-44. PMID 25913193 DOI: 10.1016/J.Cell.2015.04.011  0.752
2015 Liu Y, Cai Y, Liu W, Li XH, Rhoades E, Yan EC. Triblock peptide-linker-lipid molecular design improves potency of peptide ligands targeting family B G protein-coupled receptors. Chemical Communications (Cambridge, England). 51: 6157-60. PMID 25748072 DOI: 10.1039/C5Cc00301F  0.319
2015 Fenalti G, Zatsepin NA, Betti C, Giguere P, Han GW, Ishchenko A, Liu W, Guillemyn K, Zhang H, James D, Wang D, Weierstall U, Spence JC, Boutet S, Messerschmidt M, et al. Structural basis for bifunctional peptide recognition at human δ-opioid receptor. Nature Structural & Molecular Biology. 22: 265-8. PMID 25686086 DOI: 10.1038/Nsmb.2965  0.682
2015 Zhu H, Liu Z, Huang Y, Zhang C, Li G, Liu W. Biochemical and structural characterization of MUPP1-PDZ4 domain from Mus musculus. Acta Biochimica Et Biophysica Sinica. 47: 199-206. PMID 25662616 DOI: 10.1093/Abbs/Gmv002  0.379
2015 Brautigam CA, Deka RK, Liu WZ, Norgard MV. Insights into the potential function and membrane organization of the TP0435 (Tp17) lipoprotein from Treponema pallidum derived from structural and biophysical analyses. Protein Science : a Publication of the Protein Society. 24: 11-9. PMID 25287511 DOI: 10.1002/Pro.2576  0.331
2014 Gater DL, Saurel O, Iordanov I, Liu W, Cherezov V, Milon A. Two classes of cholesterol binding sites for the β2AR revealed by thermostability and NMR. Biophysical Journal. 107: 2305-12. PMID 25418299 DOI: 10.1016/J.Bpj.2014.10.011  0.388
2014 Yin X, Xu H, Hanson M, Liu W. GPCR crystallization using lipidic cubic phase technique. Current Pharmaceutical Biotechnology. 15: 971-979. PMID 25248558 DOI: 10.2174/1389201015666140922110325  0.687
2014 Liu W, Ishchenko A, Cherezov V. Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography. Nature Protocols. 9: 2123-34. PMID 25122522 DOI: 10.1038/Nprot.2014.141  0.387
2014 Chen P, Deng YL, Bergqvist S, Falk MD, Liu W, Timofeevski S, Brooun A. Engineering of an isolated p110α subunit of PI3Kα permits crystallization and provides a platform for structure-based drug design. Protein Science : a Publication of the Protein Society. 23: 1332-40. PMID 25043846 DOI: 10.1002/pro.2517  0.315
2014 Liu W, Wacker D, Wang C, Abola E, Cherezov V. Femtosecond crystallography of membrane proteins in the lipidic cubic phase. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20130314. PMID 24914147 DOI: 10.1098/Rstb.2013.0314  0.792
2014 Weierstall U, James D, Wang C, White TA, Wang D, Liu W, Spence JC, Bruce Doak R, Nelson G, Fromme P, Fromme R, Grotjohann I, Kupitz C, Zatsepin NA, Liu H, et al. Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. Nature Communications. 5: 3309. PMID 24525480 DOI: 10.1038/Ncomms4309  0.808
2014 Gater DL, Saurel O, Iordanov I, Liu W, Cherezov V, Milon A. Cholesterol-Gpcr (B2AR) Interaction in Lipidic Cubic Phase: Insight from 13C NMR Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.3952  0.39
2013 Liu W, Wacker D, Gati C, Han GW, James D, Wang D, Nelson G, Weierstall U, Katritch V, Barty A, Zatsepin NA, Li D, Messerschmidt M, Boutet S, Williams GJ, et al. Serial femtosecond crystallography of G protein-coupled receptors. Science (New York, N.Y.). 342: 1521-4. PMID 24357322 DOI: 10.1126/Science.1244142  0.83
2013 Gutiérrez-de-Terán H, Massink A, Rodríguez D, Liu W, Han GW, Joseph JS, Katritch I, Heitman LH, Xia L, Ijzerman AP, Cherezov V, Katritch V, Stevens RC. The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor. Structure (London, England : 1993). 21: 2175-85. PMID 24210756 DOI: 10.1016/J.Str.2013.09.020  0.727
2013 Lane JR, Chubukov P, Liu W, Canals M, Cherezov V, Abagyan R, Stevens RC, Katritch V. Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors. Molecular Pharmacology. 84: 794-807. PMID 24021214 DOI: 10.1124/Mol.113.088054  0.743
2013 Siu FY, He M, de Graaf C, Han GW, Yang D, Zhang Z, Zhou C, Xu Q, Wacker D, Joseph JS, Liu W, Lau J, Cherezov V, Katritch V, Wang MW, et al. Structure of the human glucagon class B G-protein-coupled receptor. Nature. 499: 444-9. PMID 23863937 DOI: 10.1038/Nature12393  0.811
2013 Wang C, Wu H, Katritch V, Han GW, Huang XP, Liu W, Siu FY, Roth BL, Cherezov V, Stevens RC. Structure of the human smoothened receptor bound to an antitumour agent. Nature. 497: 338-43. PMID 23636324 DOI: 10.1038/Nature12167  0.825
2013 Wacker D, Wang C, Katritch V, Han GW, Huang XP, Vardy E, McCorvy JD, Jiang Y, Chu M, Siu FY, Liu W, Xu HE, Cherezov V, Roth BL, Stevens RC. Structural features for functional selectivity at serotonin receptors. Science (New York, N.Y.). 340: 615-9. PMID 23519215 DOI: 10.1126/Science.1232808  0.816
2013 Wang C, Jiang Y, Ma J, Wu H, Wacker D, Katritch V, Han GW, Liu W, Huang XP, Vardy E, McCorvy JD, Gao X, Zhou XE, Melcher K, Zhang C, et al. Structural basis for molecular recognition at serotonin receptors. Science (New York, N.Y.). 340: 610-4. PMID 23519210 DOI: 10.1126/Science.1232807  0.825
2012 Santos JS, Asmar-Rovira GA, Han GW, Liu W, Syeda R, Cherezov V, Baker KA, Stevens RC, Montal M. Crystal structure of a voltage-gated K+ channel pore module in a closed state in lipid membranes. The Journal of Biological Chemistry. 287: 43063-70. PMID 23095758 DOI: 10.1074/jbc.M112.415091  0.495
2012 Liu W, Chun E, Thompson AA, Chubukov P, Xu F, Katritch V, Han GW, Roth CB, Heitman LH, IJzerman AP, Cherezov V, Stevens RC. Structural basis for allosteric regulation of GPCRs by sodium ions. Science (New York, N.Y.). 337: 232-6. PMID 22798613 DOI: 10.1126/Science.1219218  0.82
2012 Chun E, Thompson AA, Liu W, Roth CB, Griffith MT, Katritch V, Kunken J, Xu F, Cherezov V, Hanson MA, Stevens RC. Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors. Structure (London, England : 1993). 20: 967-76. PMID 22681902 DOI: 10.1016/J.Str.2012.04.010  0.82
2012 Thompson AA, Liu W, Chun E, Katritch V, Wu H, Vardy E, Huang XP, Trapella C, Guerrini R, Calo G, Roth BL, Cherezov V, Stevens RC. Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. Nature. 485: 395-9. PMID 22596163 DOI: 10.1038/Nature11085  0.819
2012 Wu H, Wacker D, Mileni M, Katritch V, Han GW, Vardy E, Liu W, Thompson AA, Huang XP, Carroll FI, Mascarella SW, Westkaemper RB, Mosier PD, Roth BL, Cherezov V, et al. Structure of the human κ-opioid receptor in complex with JDTic. Nature. 485: 327-32. PMID 22437504 DOI: 10.1038/Nature10939  0.808
2012 Huang L, Mao X, Abdulaev NG, Ngo T, Liu W, Ridge KD. One-step purification of a functional, constitutively activated form of visual arrestin Protein Expression and Purification. 82: 55-60. PMID 22133714 DOI: 10.1016/j.pep.2011.11.007  0.321
2012 Weyand S, Shimamura T, Shiroshi M, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S. The structure of the human histamine H1 receptor Acta Crystallographica Section a Foundations of Crystallography. 68: s29-s29. DOI: 10.1107/S0108767312099448  0.735
2012 Gater D, Saurel O, Liu W, Cherezov V, Milon A. The Monoolein-Cholesterol Cubic Phase: Characterization by NMR Spectroscopy Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.2129  0.453
2012 Santos JS, Asmar-Rovira G, Han G, Liu W, Syeda R, Stevens RC, Montal M. Structure of the Pore Module of a Voltage-Gated Channel in a Lipid Environment at 3.1 Å Resolution Biophysical Journal. 102: 265a. DOI: 10.1016/J.Bpj.2011.11.1459  0.51
2011 Joseph JS, Liu W, Kunken J, Weiss TM, Tsuruta H, Cherezov V. Characterization of lipid matrices for membrane protein crystallization by high-throughput small angle X-ray scattering. Methods (San Diego, Calif.). 55: 342-9. PMID 21903166 DOI: 10.1016/J.Ymeth.2011.08.013  0.367
2011 Tiefenbrunn T, Liu W, Chen Y, Katritch V, Stout CD, Fee JA, Cherezov V. High resolution structure of the ba3 cytochrome c oxidase from thermus thermophilus in a lipidic environment Plos One. 6. PMID 21814577 DOI: 10.1371/Journal.Pone.0022348  0.625
2011 Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S. Structure of the human histamine H1 receptor complex with doxepin. Nature. 475: 65-70. PMID 21697825 DOI: 10.1038/Nature10236  0.724
2011 Xu F, Liu W, Hanson MA, Stevens RC, Cherezov V. Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases. Crystal Growth & Design. 11: 1193-1201. PMID 21660116 DOI: 10.1021/Cg101385E  0.731
2011 Liu W, Brooks CL. Functional impact of manipulation on the relative orientation of human prolactin receptor domains. Biochemistry. 50: 5333-44. PMID 21591677 DOI: 10.1021/Bi101931U  0.428
2011 Liu W, Cherezov V. Crystallization of membrane proteins in lipidic mesophases. Journal of Visualized Experiments : Jove. PMID 21490572 DOI: 10.3791/2501  0.403
2011 Iwata S, Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC. Molecular basis of antihistamine specificity against human histamine H1 receptor Acta Crystallographica Section a Foundations of Crystallography. 67: C17-C17. DOI: 10.1107/S0108767311099648  0.709
2011 Cherezov V, Wu B, Chien E, Liu W, Xu F, Stevens RC. Structural biology of G protein-coupled receptors Acta Crystallographica Section a Foundations of Crystallography. 67: C132-C132. DOI: 10.1107/S0108767311096760  0.68
2011 Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S. Structure of the human histamine H1 receptor with doxepin Acta Crystallographica Section a Foundations of Crystallography. 67: C185-C186. DOI: 10.1107/S0108767311095377  0.735
2010 Chien EY, Liu W, Zhao Q, Katritch V, Han GW, Hanson MA, Shi L, Newman AH, Javitch JA, Cherezov V, Stevens RC. Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Science (New York, N.Y.). 330: 1091-5. PMID 21097933 DOI: 10.1126/Science.1197410  0.8
2010 Wu B, Chien EY, Mol CD, Fenalti G, Liu W, Katritch V, Abagyan R, Brooun A, Wells P, Bi FC, Hamel DJ, Kuhn P, Handel TM, Cherezov V, Stevens RC. Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science (New York, N.Y.). 330: 1066-71. PMID 20929726 DOI: 10.1126/Science.1194396  0.795
2010 Liu W, Hanson MA, Stevens RC, Cherezov V. LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment. Biophysical Journal. 98: 1539-48. PMID 20409473 DOI: 10.1016/J.Bpj.2009.12.4296  0.677
2008 Wen W, Liu W, Yan J, Zhang M. Structure basis and unconventional lipid membrane binding properties of the PH-C1 tandem of rho kinases. The Journal of Biological Chemistry. 283: 26263-73. PMID 18640982 DOI: 10.1074/Jbc.M803417200  0.306
2008 Cherezov V, Liu W, Derrick JP, Luan B, Aksimentiev A, Katritch V, Caffrey M. In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin. Proteins. 71: 24-34. PMID 18076035 DOI: 10.1002/Prot.21841  0.672
2006 Cherezov V, Yamashita E, Liu W, Zhalnina M, Cramer WA, Caffrey M. In meso structure of the cobalamin transporter, BtuB, at 1.95 A resolution. Journal of Molecular Biology. 364: 716-34. PMID 17028020 DOI: 10.1016/J.Jmb.2006.09.022  0.429
2005 Liu W, Caffrey M. Gramicidin structure and disposition in highly curved membranes Journal of Structural Biology. 150: 23-40. PMID 15797727 DOI: 10.1016/J.Jsb.2004.12.007  0.347
2000 Liu W, Vu HM, Geiduschek EP, Kearns DR. Solution structure of a mutant of transcription factor 1: implications for enhanced DNA binding. Journal of Molecular Biology. 302: 821-30. PMID 10993726 DOI: 10.1006/Jmbi.2000.4084  0.309
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