Shuzo Kaneko, Ph.D.

Affiliations: 
2007 Columbia University, New York, NY 
Area:
mRNA processing
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"Shuzo Kaneko"
Mean distance: 18.6 (cluster 11)
 
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Parents

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James L. Manley grad student 2007 Columbia
 (Functional studies of mRNA 3'-end formation and transcription termination.)
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Publications

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Kaneko S, Son J, Bonasio R, et al. (2014) Nascent RNA interaction keeps PRC2 activity poised and in check. Genes & Development. 28: 1983-8
Kaneko S, Bonasio R, Saldaña-Meyer R, et al. (2014) Interactions between JARID2 and Noncoding RNAs Regulate PRC2 Recruitment to Chromatin Molecular Cell. 53: 290-300
Kaneko S, Son J, Shen SS, et al. (2013) PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells Nature Structural and Molecular Biology. 20: 1258-1264
Rozenblatt-Rosen O, Nagaike T, Francis JM, et al. (2009) The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors. Proceedings of the National Academy of Sciences of the United States of America. 106: 755-60
Kaneko S, Chu C, Shatkin AJ, et al. (2007) Human capping enzyme promotes formation of transcriptional R loops in vitro. Proceedings of the National Academy of Sciences of the United States of America. 104: 17620-5
Kaneko S, Rozenblatt-Rosen O, Meyerson M, et al. (2007) The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' processing and transcription termination. Genes & Development. 21: 1779-89
Mandel CR, Kaneko S, Zhang H, et al. (2006) Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease. Nature. 444: 953-6
Rosonina E, Kaneko S, Manley JL. (2006) Terminating the transcript: breaking up is hard to do. Genes & Development. 20: 1050-6
Kaneko S, Manley JL. (2005) The mammalian RNA polymerase II C-terminal domain interacts with RNA to suppress transcription-coupled 3' end formation. Molecular Cell. 20: 91-103
Kleiman FE, Wu-Baer F, Fonseca D, et al. (2005) BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II. Genes & Development. 19: 1227-37
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