George L. Sutphin
Affiliations: | Molecular and Cellular Biology | University of Arizona, Tucson, AZ |
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"George Sutphin"Parents
Sign in to add mentor| Matt Kaeberlein | grad student | 2007-2012 | University of Washington | |
| (An Exploration of the Genetics and Molecular Mechanisms Underlying Conserved Longevity Interventions.) | ||||
| Ron Korstanje | post-doc | 2012-2017 | The Jackson Laboratory | |
Children
Sign in to add trainee| Raul Castro-Portuguez | grad student | 2019- | University of Arizona |
| Kayla M. Raymond | grad student | 2022- | University of Arizona |
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Publications
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| Espejo LS, DeNicola D, Chang LM, et al. (2024) The Emerging Role of 3-Hydroxyanthranilic Acid on Aging Immune Function. Biorxiv : the Preprint Server For Biology |
| Dang H, Castro-Portuguez R, Espejo L, et al. (2023) On the benefits of the tryptophan metabolite 3-hydroxyanthranilic acid in Caenorhabditis elegans and mouse aging. Nature Communications. 14: 8338 |
| Castro-Portuguez R, Sutphin GL. (2020) Kynurenine pathway, NAD synthesis, and mitochondrial function: Targeting tryptophan metabolism to promote longevity and healthspan. Experimental Gerontology. 132: 110841 |
| Castro-Portuguez R, Freitas S, Sutphin G. (2020) Inhibition of Kynurenine Metabolism and Its Effect in Mitochondrial Function in Hepatocellular Carcinoma Innovation in Aging. 4: 124-125 |
| Bubier JA, Sutphin GL, Reynolds TJ, et al. (2019) Integration of heterogeneous functional genomics data in gerontology research to find genes and pathway underlying aging across species. Plos One. 14: e0214523 |
| Sutphin GL, Sutphin GL. (2019) TARGETING TRYPTOPHAN-KYNURENINE METABOLISM TO EXTEND LIFESPAN AND TREAT AGE-ASSOCIATED DISEASE Innovation in Aging. 3: S616-S616 |
| Miller H, Fletcher M, Primitivo M, et al. (2017) Genetic interaction with temperature is an important determinant of nematode longevity. Aging Cell |
| Sutphin GL, Backer G, Sheehan S, et al. (2017) Caenorhabditis elegans orthologs of human genes differentially expressed with age are enriched for determinants of longevity. Aging Cell |
| Mendenhall A, Crane MM, Leiser S, et al. (2017) Environmental Canalization of Life Span and Gene Expression in Caenorhabditis elegans. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences |
| Sutphin G, Korstanje R. (2017) 3-HYDROXYANTHRANILIC ACID—A NOVEL MOLECULAR TARGET FOR LIFESPAN EXTENSION IN THE KYNURENINE PATHWAY Innovation in Aging. 1: 857-857 |