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Karin Borges - Publications

Affiliations: 
Emory University, Atlanta, GA 
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45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 McDonald T, Hodson MP, Bederman I, Puchowicz M, Borges K. Triheptanoin alters [U-C]-glucose incorporation into glycolytic intermediates and increases TCA cycling by normalizing the activities of pyruvate dehydrogenase and oxoglutarate dehydrogenase in a chronic epilepsy mouse model. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19837380. PMID 30890077 DOI: 10.1177/0271678X19837380  0.353
2018 McDonald T, Puchowicz M, Borges K. Impairments in Oxidative Glucose Metabolism in Epilepsy and Metabolic Treatments Thereof. Frontiers in Cellular Neuroscience. 12: 274. PMID 30233320 DOI: 10.3389/Fncel.2018.00274  0.312
2018 Tan KN, Hood R, Warren K, Pepperall D, Carrasco-Pozo C, Manzanero S, Borges K, Spratt NJ. Heptanoate is neuroprotective in vitro but triheptanoin post-treatment did not protect against middle cerebral artery occlusion in rats. Neuroscience Letters. PMID 30076987 DOI: 10.1016/J.Neulet.2018.07.045  0.321
2018 Durie D, McDonald TS, Borges K. The effect of dichloroacetate in mouse models of epilepsy. Epilepsy Research. 145: 77-81. PMID 29913407 DOI: 10.1016/J.Eplepsyres.2018.06.004  0.371
2018 Iacobaş DA, Chachua T, Iacobaş S, Benson MJ, Borges K, Velíšková J, Velíšek L. ACTH and PMX53 recover synaptic transcriptome alterations in a rat model of infantile spasms. Scientific Reports. 8: 5722. PMID 29636502 DOI: 10.1038/S41598-018-24013-X  0.326
2017 Tan KN, Simmons D, Carrasco-Pozo C, Borges K. Triheptanoin protects against status epilepticus-induced hippocampal mitochondrial dysfunctions, oxidative stress and neuronal degeneration. Journal of Neurochemistry. PMID 29222946 DOI: 10.1111/Jnc.14275  0.416
2017 McDonald TS, Borges K. Impaired hippocampal glucose metabolism during and after flurothyl-induced seizures in mice: Reduced phosphorylation coincides with reduced activity of pyruvate dehydrogenase. Epilepsia. PMID 28632902 DOI: 10.1111/Epi.13796  0.374
2017 Benson MJ, Manzanero S, Borges K. The effects of C5aR1 on leukocyte infiltration following pilocarpine-induced status epilepticus. Epilepsia. PMID 28225153 DOI: 10.1111/Epi.13698  0.369
2016 Tefera TW, Tan KN, McDonald TS, Borges K. Alternative Fuels in Epilepsy and Amyotrophic Lateral Sclerosis. Neurochemical Research. PMID 27868154 DOI: 10.1007/S11064-016-2106-7  0.308
2016 Tefera TW, Wong Y, Barkl-Luke ME, Ngo ST, Thomas NK, McDonald TS, Borges K. Triheptanoin Protects Motor Neurons and Delays the Onset of Motor Symptoms in a Mouse Model of Amyotrophic Lateral Sclerosis. Plos One. 11: e0161816. PMID 27564703 DOI: 10.1371/Journal.Pone.0161816  0.354
2016 Tan KN, Carrasco-Pozo C, McDonald TS, Puchowicz M, Borges K. Tridecanoin is anticonvulsant, antioxidant, and improves mitochondrial function. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27418037 DOI: 10.1177/0271678X16659498  0.337
2015 Hadera MG, McDonald T, Smeland OB, Meisingset TW, Eloqayli H, Jaradat S, Borges K, Sonnewald U. Modification of Astrocyte Metabolism as an Approach to the Treatment of Epilepsy: Triheptanoin and Acetyl-L-Carnitine. Neurochemical Research. PMID 26433381 DOI: 10.1007/S11064-015-1728-5  0.424
2015 Carrasco-Pozo C, Tan KN, Borges K. Sulforaphane is anticonvulsant and improves mitochondrial function. Journal of Neurochemistry. PMID 26365487 DOI: 10.1111/Jnc.13361  0.4
2015 Benson MJ, Thomas NK, Talwar S, Hodson MP, Lynch JW, Woodruff TM, Borges K. A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy models. Neurobiology of Disease. 76: 87-97. PMID 25681535 DOI: 10.1016/J.Nbd.2015.02.004  0.415
2014 Hadera MG, Smeland OB, McDonald TS, Tan KN, Sonnewald U, Borges K. Triheptanoin partially restores levels of tricarboxylic acid cycle intermediates in the mouse pilocarpine model of epilepsy. Journal of Neurochemistry. 129: 107-19. PMID 24236946 DOI: 10.1111/Jnc.12610  0.382
2014 McDonald TS, Tan KN, Hodson MP, Borges K. Alterations of hippocampal glucose metabolism by even versus uneven medium chain triglycerides. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 153-60. PMID 24169853 DOI: 10.1038/Jcbfm.2013.184  0.347
2013 Shaikh MF, Tan KN, Borges K. Anticonvulsant screening of luteolin in four mouse seizure models. Neuroscience Letters. 550: 195-9. PMID 23851253 DOI: 10.1016/J.Neulet.2013.06.065  0.338
2013 Smeland OB, Hadera MG, McDonald TS, Sonnewald U, Borges K. Brain mitochondrial metabolic dysfunction and glutamate level reduction in the pilocarpine model of temporal lobe epilepsy in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1090-7. PMID 23611869 DOI: 10.1038/Jcbfm.2013.54  0.391
2013 Kim TH, Borges K, Petrou S, Reid CA. Triheptanoin reduces seizure susceptibility in a syndrome-specific mouse model of generalized epilepsy. Epilepsy Research. 103: 101-5. PMID 23196212 DOI: 10.1016/J.Eplepsyres.2012.09.016  0.371
2013 Smeland OB, Hadera MG, McDonald T, Sonnewald U, Borges K. Mitochondrial metabolic dysfunction and glutamate reduction in the pilocarpine model of temporal lobe epilepsy in mice Journal of Neurochemistry. 125: 265-265. DOI: 10.1111/Jnc.12186  0.386
2012 Smeland OB, Meisingset TW, Borges K, Sonnewald U. Chronic acetyl-L-carnitine alters brain energy metabolism and increases noradrenaline and serotonin content in healthy mice. Neurochemistry International. 61: 100-7. PMID 22549035 DOI: 10.1016/J.Neuint.2012.04.008  0.34
2012 Thomas NK, Willis S, Sweetman L, Borges K. Triheptanoin in acute mouse seizure models. Epilepsy Research. 99: 312-7. PMID 22260920 DOI: 10.1016/J.Eplepsyres.2011.12.013  0.356
2012 Borges K, Sonnewald U. Triheptanoin--a medium chain triglyceride with odd chain fatty acids: a new anaplerotic anticonvulsant treatment? Epilepsy Research. 100: 239-44. PMID 21855298 DOI: 10.1016/J.Eplepsyres.2011.05.023  0.329
2011 Dutton SB, Sawyer NT, Kalume F, Jumbo-Lucioni P, Borges K, Catterall WA, Escayg A. Protective effect of the ketogenic diet in Scn1a mutant mice. Epilepsia. 52: 2050-6. PMID 21801172 DOI: 10.1111/J.1528-1167.2011.03211.X  0.385
2011 Samala R, Klein J, Borges K. The ketogenic diet changes metabolite levels in hippocampal extracellular fluid. Neurochemistry International. 58: 5-8. PMID 21070829 DOI: 10.1016/J.Neuint.2010.10.011  0.346
2010 Willis S, Stoll J, Sweetman L, Borges K. Anticonvulsant effects of a triheptanoin diet in two mouse chronic seizure models. Neurobiology of Disease. 40: 565-72. PMID 20691264 DOI: 10.1016/J.Nbd.2010.07.017  0.39
2009 Borges K, Willis S, Sweetman L, Stoll J. A Pre-Treatment Neurocognitive Questionnaire Provides Predictive Value For Seizure Recurrence In Newly Treated Epilepsy Epilepsia. 50: 131-132. PMID 19817824 DOI: 10.1111/J.1528-1167.2009.02377_1.X  0.31
2009 Greene JG, Borges K, Dingledine R. Quantitative transcriptional neuroanatomy of the rat hippocampus: evidence for wide-ranging, pathway-specific heterogeneity among three principal cell layers. Hippocampus. 19: 253-64. PMID 18830999 DOI: 10.1002/Hipo.20502  0.691
2009 Willis S, Samala R, Rosenberger TA, Borges K. Eicosapentaenoic and docosahexaenoic acids are not anticonvulsant or neuroprotective in acute mouse seizure models. Epilepsia. 50: 138-42. PMID 18637828 DOI: 10.1111/J.1528-1167.2008.01722.X  0.372
2008 Borges K. Mouse models: the ketogenic diet and polyunsaturated fatty acids. Epilepsia. 49: 64-6. PMID 19049591 DOI: 10.1111/J.1528-1167.2008.01838.X  0.339
2008 Samala R, Willis S, Borges K. Anticonvulsant profile of a balanced ketogenic diet in acute mouse seizure models. Epilepsy Research. 81: 119-27. PMID 18565731 DOI: 10.1016/J.Eplepsyres.2008.05.001  0.346
2008 Borges K, Gearing M, Rittling S, Sorensen ES, Kotloski R, Denhardt DT, Dingledine R. Characterization of osteopontin expression and function after status epilepticus. Epilepsia. 49: 1675-85. PMID 18522644 DOI: 10.1111/J.1528-1167.2008.01613.X  0.64
2007 Borges K, Shaw R, Dingledine R. Gene expression changes after seizure preconditioning in the three major hippocampal cell layers. Neurobiology of Disease. 26: 66-77. PMID 17239605 DOI: 10.1016/J.Nbd.2006.12.001  0.576
2006 Borges K, McDermott D, Irier H, Smith Y, Dingledine R. Degeneration and proliferation of astrocytes in the mouse dentate gyrus after pilocarpine-induced status epilepticus. Experimental Neurology. 201: 416-27. PMID 16793040 DOI: 10.1016/J.Expneurol.2006.04.031  0.692
2004 Liu Y, Ciliax BJ, Borges K, Dasigi V, Ram A, Navathe SB, Dingledine R. Comparison of two schemes for automatic keyword extraction from MEDLINE for functional gene clustering. Proceedings / Ieee Computational Systems Bioinformatics Conference, Csb. Ieee Computational Systems Bioinformatics Conference. 394-404. PMID 16448032 DOI: 10.1109/CSB.2004.1332452  0.419
2004 Borges K, McDermott DL, Dingledine R. Reciprocal changes of CD44 and GAP-43 expression in the dentate gyrus inner molecular layer after status epilepticus in mice. Experimental Neurology. 188: 1-10. PMID 15191797 DOI: 10.1016/J.Expneurol.2004.03.019  0.582
2003 Borges K, Myers SJ, Zhang S, Dingledine R. Activity of the rat GluR4 promoter in transfected cortical neurons and glia. Journal of Neurochemistry. 86: 1162-73. PMID 12911624 DOI: 10.1046/J.1471-4159.2003.01926.X  0.717
2003 Borges K, Gearing M, McDermott DL, Smith AB, Almonte AG, Wainer BH, Dingledine R. Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model. Experimental Neurology. 182: 21-34. PMID 12821374 DOI: 10.1016/S0014-4886(03)00086-4  0.627
2001 Borges K, Dingledine R. Functional organization of the GluR1 glutamate receptor promoter. The Journal of Biological Chemistry. 276: 25929-38. PMID 11340067 DOI: 10.1074/Jbc.M009105200  0.587
1999 Myers SJ, Dingledine R, Borges K. Genetic regulation of glutamate receptor ion channels. Annual Review of Pharmacology and Toxicology. 39: 221-41. PMID 10331083 DOI: 10.1146/Annurev.Pharmtox.39.1.221  0.618
1999 Dingledine R, Borges K, Bowie D, Traynelis SF. The glutamate receptor ion channels. Pharmacological Reviews. 51: 7-61. PMID 10049997  0.573
1998 Borges K, Dingledine R. AMPA receptors: molecular and functional diversity. Progress in Brain Research. 116: 153-70. PMID 9932376 DOI: 10.1016/S0079-6123(08)60436-7  0.539
1995 Borges K, Kettenmann H. Blockade of K+ channels induced by AMPA/kainate receptor activation in mouse oligodendrocyte precursor cells is mediated by Na+ entry. Journal of Neuroscience Research. 42: 579-93. PMID 8568944 DOI: 10.1002/Jnr.490420416  0.304
1995 Borges K, Wolswijk G, Ohlemeyer C, Kettenmann H. Adult rat optic nerve oligodendrocyte progenitor cells express a distinct repertoire of voltage- and ligand-gated ion channels. Journal of Neuroscience Research. 40: 591-605. PMID 7541473 DOI: 10.1002/Jnr.490400504  0.311
1994 Borges K, Ohlemeyer C, Trotter J, Kettenmann H. AMPA/kainate receptor activation in murine oligodendrocyte precursor cells leads to activation of a cation conductance, calcium influx and blockade of delayed rectifying K+ channels. Neuroscience. 63: 135-49. PMID 7898644 DOI: 10.1016/0306-4522(94)90012-4  0.347
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