Year |
Citation |
Score |
2021 |
Olszewski K, Barsotti A, Feng XJ, Momcilovic M, Liu KG, Kim JI, Morris K, Lamarque C, Gaffney J, Yu X, Patel JP, Rabinowitz JD, Shackelford DB, Poyurovsky MV. Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors. Cell Chemical Biology. PMID 34715056 DOI: 10.1016/j.chembiol.2021.10.007 |
0.715 |
|
2020 |
Liu KG, Kim JI, Olszewski K, Barsotti AM, Morris K, Lamarque C, Yu X, Gaffney J, Feng XJ, Patel J, Poyurovsky M. Discovery and Optimization of Glucose Uptake Inhibitors. Journal of Medicinal Chemistry. PMID 32282207 DOI: 10.1021/acs.jmedchem.9b02153 |
0.7 |
|
2014 |
Poyurovsky MV, Prives C. P53: Guardian of the metabolome P53 in the Clinics. 47-64. DOI: 10.1007/978-1-4614-3676-8_3 |
0.67 |
|
2012 |
Biderman L, Poyurovsky MV, Assia Y, Manley JL, Prives C. MdmX is required for p53 interaction with and full induction of the Mdm2 promoter after cellular stress. Molecular and Cellular Biology. 32: 1214-25. PMID 22290440 DOI: 10.1128/Mcb.06150-11 |
0.831 |
|
2011 |
Herman AG, Hayano M, Poyurovsky MV, Shimada K, Skouta R, Prives C, Stockwell BR. Discovery of Mdm2-MdmX E3 ligase inhibitors using a cell-based ubiquitination assay. Cancer Discovery. 1: 312-25. PMID 22586610 DOI: 10.1158/2159-8290.Cd-11-0104 |
0.669 |
|
2010 |
Peart MJ, Poyurovsky MV, Kass EM, Urist M, Verschuren EW, Summers MK, Jackson PK, Prives C. APC/C(Cdc20) targets E2F1 for degradation in prometaphase. Cell Cycle (Georgetown, Tex.). 9: 3956-64. PMID 20948288 DOI: 10.4161/Cc.9.19.13162 |
0.774 |
|
2010 |
Priest C, Prives C, Poyurovsky MV. Deconstructing nucleotide binding activity of the Mdm2 RING domain Nucleic Acids Research. 38: 7587-7598. PMID 20671028 DOI: 10.1093/Nar/Gkq669 |
0.712 |
|
2010 |
Poyurovsky MV, Prives C. P53 and aging: A fresh look at an old paradigm. Aging. 2: 380-2. PMID 20657036 DOI: 10.18632/AGING.100179 |
0.568 |
|
2010 |
Poyurovsky MV, Katz C, Laptenko O, Beckerman R, Lokshin M, Ahn J, Byeon IJ, Gabizon R, Mattia M, Zupnick A, Brown LM, Friedler A, Prives C. The C terminus of p53 binds the N-terminal domain of MDM2. Nature Structural & Molecular Biology. 17: 982-9. PMID 20639885 DOI: 10.1038/Nsmb.1872 |
0.749 |
|
2010 |
Suzuki S, Tanaka T, Poyurovsky MV, Nagano H, Mayama T, Ohkubo S, Lokshin M, Hosokawa H, Nakayama T, Suzuki Y, Sugano S, Sato E, Nagao T, Yokote K, Tatsuno I, et al. Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species. Proceedings of the National Academy of Sciences of the United States of America. 107: 7461-6. PMID 20351271 DOI: 10.1073/Pnas.1002459107 |
0.764 |
|
2009 |
Zhu Y, Poyurovsky MV, Li Y, Biderman L, Stahl J, Jacq X, Prives C. Ribosomal protein S7 is both a regulator and a substrate of MDM2. Molecular Cell. 35: 316-26. PMID 19683495 DOI: 10.1016/J.Molcel.2009.07.014 |
0.789 |
|
2009 |
Ahn J, Poyurovsky MV, Baptiste N, Beckerman R, Cain C, Mattia M, McKinney K, Zhou J, Zupnick A, Gottifredi V, Prives C. Dissection of the sequence-specific DNA binding and exonuclease activities reveals a superactive yet apoptotically impaired mutant p53 protein. Cell Cycle (Georgetown, Tex.). 8: 1603-15. PMID 19462533 DOI: 10.4161/Cc.8.10.8548 |
0.635 |
|
2009 |
Kass EM, Poyurovsky MV, Zhu Y, Prives C. Mdm2 and PCAF increase Chk2 ubiquitination and degradation independently of their intrinsic E3 ligase activities. Cell Cycle (Georgetown, Tex.). 8: 430-7. PMID 19176998 DOI: 10.4161/Cc.8.3.7624 |
0.788 |
|
2007 |
Poyurovsky MV, Priest C, Kentsis A, Borden KLB, Pan ZQ, Pavletich N, Prives C. The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity Embo Journal. 26: 90-101. PMID 17170710 DOI: 10.1038/Sj.Emboj.7601465 |
0.69 |
|
2006 |
Poyurovsky MV, Prives C. Unleashing the power of p53: lessons from mice and men. Genes & Development. 20: 125-31. PMID 16418478 DOI: 10.1101/Gad.1397506 |
0.441 |
|
2004 |
Urist M, Tanaka T, Poyurovsky MV, Prives C. p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2. Genes & Development. 18: 3041-54. PMID 15601819 DOI: 10.1101/Gad.1221004 |
0.796 |
|
2004 |
Gottifredi V, McKinney K, Poyurovsky MV, Prives C. Decreased p21 levels are required for efficient restart of DNA synthesis after S phase block. The Journal of Biological Chemistry. 279: 5802-10. PMID 14597617 DOI: 10.1074/Jbc.M310373200 |
0.84 |
|
2003 |
Poyurovsky MV, Jacq X, Ma C, Karni-Schmidt O, Parker PJ, Chalfie M, Manley JL, Prives C. Nucleotide binding by the Mdm2 RING domain facilitates Arf-independent Mdm2 nucleolar localization. Molecular Cell. 12: 875-87. PMID 14580339 DOI: 10.1016/S1097-2765(03)00400-3 |
0.816 |
|
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