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F. A. Romero, Ph.D. - Publications

Affiliations: 
University of Kansas, Lawrence, KS, United States 
Area:
neurotransmitters and drugs affecting them in the central nervous system
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2007 Romero FA, Du W, Hwang I, Rayl TJ, Kimball FS, Leung D, Hoover HS, Apodaca RL, Breitenbucher JG, Cravatt BF, Boger DL. Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase. Journal of Medicinal Chemistry. 50: 1058-68. PMID 17279740 DOI: 10.1021/Jm0611509  0.304
2005 Grunewald GL, Romero FA, Criscione KR. Nanomolar inhibitors of CNS epinephrine biosynthesis: (R)-(+)-3-fluoromethyl-7-(N-substituted aminosulfonyl)-1,2,3,4-tetrahydroisoquinolines as potent and highly selective inhibitors of phenylethanolamine N-methyltransferase1. Journal of Medicinal Chemistry. 48: 1806-12. PMID 15771426 DOI: 10.1021/Jm049594X  0.571
2005 Grunewald GL, Romero FA, Seim MR, Criscione KR, Deupree JD, Spackman CC, Bylund DB. Exploring the active site of phenylethanolamine N-methyltransferase with 3-hydroxyethyl- and 3-hydroxypropyl-7-substituted-1,2,3,4-tetrahydroisoquinolines. Bioorganic & Medicinal Chemistry Letters. 15: 1143-7. PMID 15686930 DOI: 10.1016/J.Bmcl.2004.12.013  0.529
2005 Grunewald GL, Romero FA, Chieu AD, Fincham KJ, Bhat SR, Criscione KR. Exploring the active site of phenylethanolamine N-methyltransferase: 3-alkyl-7-substituted-1,2,3,4-tetrahydroisoquinoline inhibitors. Bioorganic & Medicinal Chemistry. 13: 1261-73. PMID 15670935 DOI: 10.1016/J.Bmc.2004.11.015  0.674
2005 Grunewald GL, Romero FA, Criscione KR. 3-hydroxymethyl-7-(N-substituted aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline inhibitors of phenylethanolamine N-methyltransferase that display remarkable potency and selectivity. Journal of Medicinal Chemistry. 48: 134-40. PMID 15634007 DOI: 10.1021/Jm049368N  0.628
2004 Romero FA, Vodonick SM, Criscione KR, McLeish MJ, Grunewald GL. Inhibitors of phenylethanolamine N-methyltransferase that are predicted to penetrate the blood-brain barrier: design, synthesis, and evaluation of 3-fluoromethyl-7-(N-substituted aminosulfonyl)-1,2,3,4-tetrahydroisoquinolines that possess low affinity toward the alpha2-adrenoceptor. Journal of Medicinal Chemistry. 47: 4483-93. PMID 15317460 DOI: 10.1021/Jm0400653  0.663
2002 Lankin DC, Grunewald GL, Romero FA, Oren IY, Snyder JP. The NH---FC dipole orientation effect for pendant exocyclic CH(2)F. Organic Letters. 4: 3557-60. PMID 12375886 DOI: 10.1021/ol026358c  0.477
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