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John R. Jalas, Ph.D. - Publications

Affiliations: 
2003 University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
protein engineering, protein prenylation and cellular patterning
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6 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2005 Jalas JR, Hecht SS, Murphy SE. Cytochrome P450 enzymes as catalysts of metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco specific carcinogen. Chemical Research in Toxicology. 18: 95-110. PMID 15720112 DOI: 10.1021/Tx049847P  0.356
2004 Jalas JR, Seetharaman M, Hecht SS, Murphy SE. Molecular modelling of CYP2A enzymes: application to metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 34: 515-33. PMID 15277013 DOI: 10.1080/00498250410001713131  0.374
2003 Jalas JR, Ding X, Murphy SE. Comparative metabolism of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol by rat cytochrome P450 2A3 and human cytochrome P450 2A13. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 1199-202. PMID 12975327 DOI: 10.1124/Dmd.31.10.1199  0.449
2003 Jalas JR, McIntee EJ, Kenney PM, Upadhyaya P, Peterson LA, Hecht SS. Stereospecific deuterium substitution attenuates the tumorigenicity and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Chemical Research in Toxicology. 16: 794-806. PMID 12807363 DOI: 10.1021/Tx034022L  0.435
2003 Jalas JR, Hecht SS. Synthesis of stereospecifically deuterated 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) iastereomers and metabolism by A/J mouse lung microsomes and cytochrome p450 2A5. Chemical Research in Toxicology. 16: 782-93. PMID 12807362 DOI: 10.1021/Tx034021T  0.489
2003 Cheng G, Shi Y, Sturla SJ, Jalas JR, McIntee EJ, Villalta PW, Wang M, Hecht SS. Reactions of formaldehyde plus acetaldehyde with deoxyguanosine and DNA: formation of cyclic deoxyguanosine adducts and formaldehyde cross-links. Chemical Research in Toxicology. 16: 145-52. PMID 12588185 DOI: 10.1021/Tx025614R  0.312
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