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John W. Tomsho, Ph.D. - Publications

Affiliations: 
1994-1998 Chemistry & Biochemistry Phiiladelphia College of Pharmacy and Science 
 1998-2005 Medicinal Chemistry University of Michigan (Chemistry Tree) 
 2005-2012 Chemistry The Pennsylvania State University-Eberly College of Science 
 2012-2022 Chemistry & Biochemistry University of the Sciences in Philadelphia 
 2022- Chemistry & Biochemistry Saint Joseph's University, Merion Station, PA, United States 
Area:
Design, synthesis, and biological evaluation of novel chemical interventions for the treatment of infectious diseases, Expanding the use of boronic acids in bioorganic and medicinal chemistry
Website:
https://directory.sju.edu/john-tomsho
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Alhthlol LM, Orme CL, Jefferis BS, Herter SA, Kemper HE, Tomsho JW. Synthesis of Boron-Containing Nucleoside Analogs. The Journal of Organic Chemistry. 89: 1556-1566. PMID 38227951 DOI: 10.1021/acs.joc.3c02179  0.589
2019 Mancini G, Bouda M, Gamrat JM, Tomsho JW. Synthesis and Antimicrobial Evaluation of γ-Borono Phosphonate Compounds in and . Acs Omega. 4: 14551-14559. PMID 31528809 DOI: 10.1021/acsomega.9b01774  0.688
2018 Trimpin S, Pophristic M, Adeniji-Adele A, Tomsho JW, McEwen CN. Vacuum Matrix-Assisted Ionization Source offering Simplicity, Sensitivity, and Exceptional Robustness in Mass Spectrometry. Analytical Chemistry. PMID 30130391 DOI: 10.1021/Acs.Analchem.8B03378  0.329
2018 Gamrat JM, Mancini G, Burke SJ, Colandrea RC, Sadowski NR, Figula BC, Tomsho JW. Protection of the Benzoxaborole Moiety: Synthesis and Functionalization of Zwitterionic Benzoxaborole Complexes. The Journal of Organic Chemistry. PMID 29724096 DOI: 10.1021/Acs.Joc.8B00677  0.544
2015 El-Mowafi SA, Sineva E, Alumasa JN, Nicoloff H, Tomsho JW, Ades SE, Keiler KC. Identification of inhibitors of a bacterial sigma factor using a new high-throughput screening assay. Antimicrobial Agents and Chemotherapy. 59: 193-205. PMID 25331704 DOI: 10.1128/Aac.03979-14  0.394
2015 Burke SJ, Gamrat JM, Santhouse JR, Tomares DT, Tomsho JW. Potassium haloalkyltrifluoroborate salts: Synthesis, application, and reversible ligand replacement with MIDA Tetrahedron Letters. 56: 5500-5503. DOI: 10.1016/J.Tetlet.2015.08.012  0.615
2015 Tony Liu C, Tomsho JW, Benkovic SJ. Corrigendum to "The unique chemistry of benzoxaboroles: Current and emerging applications in biotechnology and therapeutic treatments" [Bioorg. Med. Chem. 22 (2014) 4462-4473] Bioorganic and Medicinal Chemistry. DOI: 10.1016/J.Bmc.2015.04.043  0.508
2014 Liu CT, Tomsho JW, Benkovic SJ. The unique chemistry of benzoxaboroles: current and emerging applications in biotechnology and therapeutic treatments. Bioorganic & Medicinal Chemistry. 22: 4462-73. PMID 24864040 DOI: 10.1016/J.Bmc.2014.04.065  0.551
2012 Tomsho JW, Pal A, Hall DG, Benkovic SJ. Ring Structure and Aromatic Substituent Effects on the pK a of the Benzoxaborole Pharmacophore. Acs Medicinal Chemistry Letters. 3: 48-52. PMID 24900370 DOI: 10.1021/Ml200215J  0.601
2012 Tomsho JW, Benkovic SJ. Examination of the reactivity of benzoxaboroles and related compounds with a cis-diol. The Journal of Organic Chemistry. 77: 11200-9. PMID 23116424 DOI: 10.1021/Jo302264G  0.644
2012 Tomsho JW, Benkovic SJ. Elucidation of the mechanism of the reaction between phenylboronic acid and a model diol, Alizarin Red S. The Journal of Organic Chemistry. 77: 2098-106. PMID 22283713 DOI: 10.1021/Jo202250D  0.601
2011 Baker SJ, Tomsho JW, Benkovic SJ. Boron-containing inhibitors of synthetases. Chemical Society Reviews. 40: 4279-85. PMID 21298158 DOI: 10.1039/C0Cs00131G  0.605
2010 An S, Deng Y, Tomsho JW, Kyoung M, Benkovic SJ. Microtubule-assisted mechanism for functional metabolic macromolecular complex formation. Proceedings of the National Academy of Sciences of the United States of America. 107: 12872-6. PMID 20615962 DOI: 10.1073/Pnas.1008451107  0.734
2010 McGuire JJ, Bartley DM, Tomsho JW, Haile WH, Coward JK. Corrigendum to "Inhibition of human folylpolyglutamate synthetase by diastereomeric phosphinic acid mimics of the tetrahedral intermediate" [Archives of Biochemistry and Biophysics 488 (2009) 140-145] (DOI:10.1016/j.abb.2009.06.017) Archives of Biochemistry and Biophysics. 493: 250. DOI: 10.1016/J.Abb.2009.11.011  0.77
2009 McGuire JJ, Bartley DM, Tomsho JW, Haile WH, Coward JK. Inhibition of human folylpolyglutamate synthetase by diastereomeric phosphinic acid mimics of the tetrahedral intermediate. Archives of Biochemistry and Biophysics. 488: 140-5. PMID 19563773 DOI: 10.1016/J.Abb.2009.06.017  0.751
2008 Tomsho JW, Moran RG, Coward JK. Concentration-dependent processivity of multiple glutamate ligations catalyzed by folylpoly-gamma-glutamate synthetase. Biochemistry. 47: 9040-50. PMID 18672898 DOI: 10.1021/Bi800406W  0.63
2008 Tomsho JW, Benkovic SJ. Unnatural translation initiation. Acs Chemical Biology. 3: 87-8. PMID 18278847 DOI: 10.1021/Cb8000233  0.593
2007 Cheng L, Naumann TA, Horswill AR, Hong SJ, Venters BJ, Tomsho JW, Benkovic SJ, Keiler KC. Discovery of antibacterial cyclic peptides that inhibit the ClpXP protease. Protein Science : a Publication of the Protein Society. 16: 1535-42. PMID 17600141 DOI: 10.1110/Ps.072933007  0.655
2005 Tomsho JW, McGuire JJ, Coward JK. Synthesis of (6R)- and (6S)-5,10-dideazatetrahydrofolate oligo-gamma-glutamates: kinetics of multiple glutamate ligations catalyzed by folylpoly-gamma-glutamate synthetase. Organic & Biomolecular Chemistry. 3: 3388-98. PMID 16132101 DOI: 10.1039/B505907K  0.627
2000 Davis WR, Tomsho J, Nikam S, Cook EM, Somand D, Peliska JA. Inhibition of HIV-1 reverse transcriptase-catalyzed DNA strand transfer reactions by 4-chlorophenylhydrazone of mesoxalic acid. Biochemistry. 39: 14279-91. PMID 11087377 DOI: 10.1021/Bi0015764  0.436
1999 Tomsho J, McKee J, Zanger M. A microscale synthesis of the diastereomers of 2,3-dibromosuccinic acid Journal of Chemical Education. 76: 73-74.  0.424
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