Isaac Kohane - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
Integrative genomics of cancer and development

88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Goldberg CB, Adams L, Blumenthal D, Brennan PF, Brown N, Butte AJ, Cheatham M, deBronkart D, Dixon J, Drazen J, Evans BJ, Hoffman SM, Holmes C, Lee P, Manrai AK, ... ... Kohane IS, et al. To do no harm - and the most good - with AI in health care. Nature Medicine. PMID 38388841 DOI: 10.1038/s41591-024-02853-7  0.38
2021 Zhang HG, Hejblum BP, Weber GM, Palmer NP, Churchill SE, Szolovits P, Murphy SN, Liao KP, Kohane IS, Cai T. ATLAS: an automated association test using probabilistically linked health records with application to genetic studies. Journal of the American Medical Informatics Association : Jamia. PMID 34608931 DOI: 10.1093/jamia/ocab187  0.57
2020 Madhavan S, Bastarache L, Brown JS, Butte AJ, Dorr DA, Embi PJ, Friedman CP, Johnson KB, Moore JH, Kohane IS, Payne PRO, Tenenbaum JD, Weiner MG, Wilcox AB, Ohno-Machado L. Use of electronic health records to support a public health response to the COVID-19 pandemic in the United States: a perspective from 15 academic medical centers. Journal of the American Medical Informatics Association : Jamia. PMID 33260207 DOI: 10.1093/jamia/ocaa287  0.459
2020 Norgeot B, Quer G, Beaulieu-Jones BK, Torkamani A, Dias R, Gianfrancesco M, Arnaout R, Kohane IS, Saria S, Topol E, Obermeyer Z, Yu B, Butte AJ. Minimum information about clinical artificial intelligence modeling: the MI-CLAIM checklist. Nature Medicine. 26: 1320-1324. PMID 32908275 DOI: 10.1038/S41591-020-1041-Y  0.423
2020 Luo Y, Eran A, Palmer N, Avillach P, Levy-Moonshine A, Szolovits P, Kohane IS. A multidimensional precision medicine approach identifies an autism subtype characterized by dyslipidemia. Nature Medicine. PMID 32778826 DOI: 10.1038/S41591-020-1007-0  0.573
2020 Sáez C, Gutiérrez-Sacristán A, Kohane I, García-Gómez JM, Avillach P. EHRtemporalVariability: delineating temporal data-set shifts in electronic health records. Gigascience. 9. PMID 32729900 DOI: 10.1093/Gigascience/Giaa079  0.31
2019 Zhang Y, Cai T, Yu S, Cho K, Hong C, Sun J, Huang J, Ho YL, Ananthakrishnan AN, Xia Z, Shaw SY, Gainer V, Castro V, Link N, Honerlaw J, ... ... Kohane I, et al. High-throughput phenotyping with electronic medical record data using a common semi-supervised approach (PheCAP). Nature Protocols. PMID 31748751 DOI: 10.1038/S41596-019-0227-6  0.626
2019 Liao KP, Sun J, Cai TA, Link N, Hong C, Huang J, Huffman JE, Gronsbell J, Zhang Y, Ho YL, Castro V, Gainer V, Murphy SN, O'Donnell CJ, Gaziano JM, ... ... Kohane IS, et al. High-throughput multimodal automated phenotyping (MAP) with application to PheWAS. Journal of the American Medical Informatics Association : Jamia. 26: 1255-1262. PMID 31613361 DOI: 10.1093/Jamia/Ocz066  0.562
2019 Kohane I, Berg JM. Donald A. B. Lindberg (1933-2019). Science (New York, N.Y.). 366: 37. PMID 31604294 DOI: 10.1126/Science.Aaz3644  0.32
2019 Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Savova G, Shaw SY, Churchill S, Burke KE, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ. Use of narrative concepts in the EHR to validate genetic determinants of treatment response in a virtual inflammatory bowel disease cohort. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 31404664 DOI: 10.1016/J.Cgh.2019.08.005  0.353
2019 McDermott M, Wang J, Zhao WN, Sheridan SD, Szolovits P, Kohane I, Haggarty SJ, Perlis RH. Deep Learning Benchmarks on L1000 Gene Expression Data. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 30990190 DOI: 10.1109/Tcbb.2019.2910061  0.566
2019 Hejblum BP, Weber GM, Liao KP, Palmer NP, Churchill S, Shadick NA, Szolovits P, Murphy SN, Kohane IS, Cai T. Probabilistic record linkage of de-identified research datasets with discrepancies using diagnosis codes. Scientific Data. 6: 180298. PMID 30620344 DOI: 10.1038/Sdata.2018.298  0.563
2017 Yu S, Ma Y, Gronsbell J, Cai T, Ananthakrishnan AN, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Liao KP, Cai T. Enabling phenotypic big data with PheNorm. Journal of the American Medical Informatics Association : Jamia. PMID 29126253 DOI: 10.1093/Jamia/Ocx111  0.561
2017 Kothari C, Wack M, Hassen-Khodja C, Finan S, Savova G, O'Boyle M, Bliss G, Cornell A, Horn EJ, Davis R, Jacobs J, Kohane I, Avillach P. Phelan-McDermid syndrome data network: Integrating patient reported outcomes with clinical notes and curated genetic reports. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 28862395 DOI: 10.1002/Ajmg.B.32579  0.318
2016 Yu S, Chakrabortty A, Liao KP, Cai T, Ananthakrishnan AN, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T. Surrogate-assisted feature extraction for high-throughput phenotyping. Journal of the American Medical Informatics Association : Jamia. PMID 27632993 DOI: 10.1093/Jamia/Ocw135  0.561
2016 Manrai AK, Funke BH, Rehm HL, Olesen MS, Maron BA, Szolovits P, Margulies DM, Loscalzo J, Kohane IS. Genetic Misdiagnoses and the Potential for Health Disparities. The New England Journal of Medicine. 375: 655-65. PMID 27532831 DOI: 10.1056/Nejmsa1507092  0.545
2016 Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Savova G, Churchill S, Karlson EW, Kohane I, Liao KP, Murphy SN. Comparative Effectiveness of Infliximab and Adalimumab in Crohn's Disease and Ulcerative Colitis. Inflammatory Bowel Diseases. PMID 26933751 DOI: 10.1097/Mib.0000000000000754  0.316
2016 Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I. Statin use is Associated With Reduced Risk of Colorectal Cancer in Patients with Inflammatory Bowel Diseases. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 26905907 DOI: 10.1016/J.Cgh.2016.02.017  0.36
2016 Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw S, Churchill S, Karlson E, Murphy S, Liao K, Kohane I. 1122 Statin Use Is Associated With Reduced Risk of Colorectal Cancer in Inflammatory Bowel Diseases Gastroenterology. 150: S225-S226. DOI: 10.1016/S0016-5085(16)30831-9  0.301
2015 Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Savova G, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I. Identification of Nonresponse to Treatment Using Narrative Data in an Electronic Health Record Inflammatory Bowel Disease Cohort. Inflammatory Bowel Diseases. PMID 26332313 DOI: 10.1097/Mib.0000000000000580  0.352
2015 Liao KP, Ananthakrishnan AN, Kumar V, Xia Z, Cagan A, Gainer VS, Goryachev S, Chen P, Savova GK, Agniel D, Churchill S, Lee J, Murphy SN, Plenge RM, Szolovits P, ... Kohane I, et al. Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts. Plos One. 10: e0136651. PMID 26301417 DOI: 10.1371/Journal.Pone.0136651  0.61
2015 Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ. Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases. Inflammatory Bowel Diseases. PMID 26241000 DOI: 10.1097/Mib.0000000000000524  0.318
2015 Doshi-Velez F, Avillach P, Palmer N, Bousvaros A, Ge Y, Fox K, Steinberg G, Spettell C, Juster I, Kohane I. Prevalence of Inflammatory Bowel Disease Among Patients with Autism Spectrum Disorders. Inflammatory Bowel Diseases. 21: 2281-8. PMID 26218138 DOI: 10.1097/Mib.0000000000000502  0.307
2015 Yu S, Liao KP, Shaw SY, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T. Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources. Journal of the American Medical Informatics Association : Jamia. PMID 25929596 DOI: 10.1093/Jamia/Ocv034  0.488
2015 Liao KP, Cai T, Savova GK, Murphy SN, Karlson EW, Ananthakrishnan AN, Gainer VS, Shaw SY, Xia Z, Szolovits P, Churchill S, Kohane I. Development of phenotype algorithms using electronic medical records and incorporating natural language processing. Bmj (Clinical Research Ed.). 350: h1885. PMID 25911572 DOI: 10.1136/Bmj.H1885  0.599
2015 Diogo D, Bastarache L, Liao KP, Graham RR, Fulton RS, Greenberg JD, Eyre S, Bowes J, Cui J, Lee A, Pappas DA, Kremer JM, Barton A, Coenen MJ, Franke B, ... ... Kohane I, et al. TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits. Plos One. 10: e0122271. PMID 25849893 DOI: 10.1371/Journal.Pone.0122271  0.305
2015 Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Colonoscopy is associated with a reduced risk for colon cancer and mortality in patients with inflammatory bowel diseases. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 13: 322-329.e1. PMID 25041865 DOI: 10.1016/J.Cgh.2014.07.018  0.326
2014 Sinnott JA, Dai W, Liao KP, Shaw SY, Ananthakrishnan AN, Gainer VS, Karlson EW, Churchill S, Szolovits P, Murphy S, Kohane I, Plenge R, Cai T. Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records. Human Genetics. 133: 1369-82. PMID 25062868 DOI: 10.1007/S00439-014-1466-9  0.617
2014 Brownstein CA, Beggs AH, Homer N, Merriman B, Yu TW, Flannery KC, DeChene ET, Towne MC, Savage SK, Price EN, Holm IA, Luquette LJ, Lyon E, Majzoub J, Neupert P, ... ... Kohane IS, et al. An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biology. 15: R53. PMID 24667040 DOI: 10.1186/Gb-2014-15-3-R53  0.555
2014 Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases. Alimentary Pharmacology & Therapeutics. 39: 1136-42. PMID 24641590 DOI: 10.1111/Apt.12706  0.584
2014 Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Scoville E, Konijeti GG, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Thromboprophylaxis is associated with reduced post-hospitalization venous thromboembolic events in patients with inflammatory bowel diseases. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 12: 1905-10. PMID 24632349 DOI: 10.1016/J.Cgh.2014.02.034  0.576
2014 Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease. Journal of Crohn's & Colitis. 8: 956-63. PMID 24559536 DOI: 10.1016/J.Crohns.2014.01.019  0.587
2014 Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Serum inflammatory markers and risk of colorectal cancer in patients with inflammatory bowel diseases. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 12: 1342-8.e1. PMID 24407106 DOI: 10.1016/J.Cgh.2013.12.030  0.602
2014 Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Association between reduced plasma 25-hydroxy vitamin D and increased risk of cancer in patients with inflammatory bowel diseases. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 12: 821-7. PMID 24161349 DOI: 10.1016/J.Cgh.2013.10.011  0.586
2014 Liao KP, Diogo D, Cui J, Cai T, Okada Y, Gainer VS, Murphy SN, Gupta N, Mirel D, Ananthakrishnan AN, Szolovits P, Shaw SY, Raychaudhuri S, Churchill S, Kohane I, et al. Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls. Annals of the Rheumatic Diseases. 73: 1170-5. PMID 23716066 DOI: 10.1136/Annrheumdis-2012-203202  0.549
2014 Ananthakrishnan A, Cagan A, Cai T, Gainer V, Shaw S, Churchill S, Karlsin E, Murphy S, Kohane I, Liao K. Colonoscopy Is Associated With a Reduced Risk of Colon Cancer and Mortality in Patients With Inflammatory Bowel Diseases: ACG Auxiliary Award - Member: 2202 The American Journal of Gastroenterology. 109. DOI: 10.14309/00000434-201410002-02202  0.315
2014 Kumar V, Liao K, Cheng S, Yu S, Kartoun U, Brettman A, Gainer V, Cagan A, Murphy S, Savova G, Chen P, Szolovits P, Xia Z, Karlson E, Plenge R, ... ... Kohane I, et al. NATURAL LANGUAGE PROCESSING IMPROVES PHENOTYPIC ACCURACY IN AN ELECTRONIC MEDICAL RECORD COHORT OF TYPE 2 DIABETES AND CARDIOVASCULAR DISEASE Journal of the American College of Cardiology. 63: A1359. DOI: 10.1016/S0735-1097(14)61359-0  0.603
2014 Ananthakrishnan AN, Cagan A, Cheng S, Gainer VS, Cai T, Shaw S, Szolovits P, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. 302 Extraintestinal Cancers and Mortality in Patients With Primary Sclerosing Cholangitis and Inflammatory Bowel Disease Gastroenterology. 146: S-906. DOI: 10.1016/S0016-5085(14)63293-5  0.577
2014 Ananthakrishnan AN, Cagan A, Gainer VS, Cheng S, Cai T, Shaw S, Szolovits P, Karlson EW, Churchill S, Murphy SN, Kohane I, Liao KP. Mo1263 Higher Plasma Vitamin D is Associated With Reduced Risk of Clostridium difficile Infection in Patients With Inflammatory Bowel Disease Gastroenterology. 146: S-601. DOI: 10.1016/S0016-5085(14)62178-8  0.583
2014 Ananthakrishnan AN, Cagan A, Gainer VS, Cheng S, Cai T, Shaw S, Scoville E, Konijeti GG, Szolovits P, Karlson EW, Churchill S, Murphy SN, Kohane I, Liao KP. Mo1262 Pharmacologic Thromboprophylaxis Reduces Post-Hospitalization Venous Thromboembolic Events in Patients With Inflammatory Bowel Disease Gastroenterology. 146: S-600-S-601. DOI: 10.1016/S0016-5085(14)62177-6  0.583
2014 Ananthakrishnan AN, Cheng S, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw S, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP. Su1324 Serum Inflammatory Markers and Risk of Colorectal Cancer in Patients With Inflammatory Bowel Disease Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)61569-9  0.583
2013 Xia Z, Secor E, Chibnik LB, Bove RM, Cheng S, Chitnis T, Cagan A, Gainer VS, Chen PJ, Liao KP, Shaw SY, Ananthakrishnan AN, Szolovits P, Weiner HL, Karlson EW, ... ... Kohane IS, et al. Modeling disease severity in multiple sclerosis using electronic health records. Plos One. 8: e78927. PMID 24244385 DOI: 10.1371/Journal.Pone.0078927  0.565
2013 Manrai AK, Kohane IS, Szolovits P. Urinary-cell mRNA and acute kidney-transplant rejection. The New England Journal of Medicine. 369: 1859. PMID 24195557 DOI: 10.1056/NEJMc1310006#SA3  0.461
2013 Overby CL, Kohane I, Kannry JL, Williams MS, Starren J, Bottinger E, Gottesman O, Denny JC, Weng C, Tarczy-Hornoch P, Hripcsak G. Opportunities for genomic clinical decision support interventions. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 817-23. PMID 24051479 DOI: 10.1038/Gim.2013.128  0.318
2013 Ananthakrishnan AN, Cagan A, Gainer VS, Cai T, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw SY, Churchill S, Karlson EW, Kohane I, Plenge RM, et al. Normalization of plasma 25-hydroxy vitamin D is associated with reduced risk of surgery in Crohn's disease. Inflammatory Bowel Diseases. 19: 1921-7. PMID 23751398 DOI: 10.1097/Mib.0B013E3182902Ad9  0.579
2013 Gottesman O, Kuivaniemi H, Tromp G, Faucett WA, Li R, Manolio TA, Sanderson SC, Kannry J, Zinberg R, Basford MA, Brilliant M, Carey DJ, Chisholm RL, Chute CG, Connolly JJ, ... ... Kohane I, et al. The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 15: 761-71. PMID 23743551 DOI: 10.1038/Gim.2013.72  0.303
2013 Ananthakrishnan AN, Cai T, Savova G, Cheng SC, Chen P, Perez RG, Gainer VS, Murphy SN, Szolovits P, Xia Z, Shaw S, Churchill S, Karlson EW, Kohane I, Plenge RM, et al. Improving case definition of Crohn's disease and ulcerative colitis in electronic medical records using natural language processing: a novel informatics approach. Inflammatory Bowel Diseases. 19: 1411-20. PMID 23567779 DOI: 10.1097/Mib.0B013E31828133Fd  0.616
2013 Ananthakrishnan AN, Gainer VS, Cai T, Perez RG, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw S, Churchill S, Karlson EW, Kohane I, Perlis RH, et al. Similar risk of depression and anxiety following surgery or hospitalization for Crohn's disease and ulcerative colitis. The American Journal of Gastroenterology. 108: 594-601. PMID 23337479 DOI: 10.1038/Ajg.2012.471  0.573
2013 Ananthakrishnan AN, Gainer VS, Perez RG, Cai T, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw SY, Churchill S, Karlson EW, Kohane I, Perlis RH, et al. Psychiatric co-morbidity is associated with increased risk of surgery in Crohn's disease. Alimentary Pharmacology & Therapeutics. 37: 445-54. PMID 23289600 DOI: 10.1111/Apt.12195  0.586
2013 Liao KP, Kurreeman F, Li G, Duclos G, Murphy S, Guzman R, Cai T, Gupta N, Gainer V, Schur P, Cui J, Denny JC, Szolovits P, Churchill S, Kohane I, et al. Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls. Arthritis and Rheumatism. 65: 571-81. PMID 23233247 DOI: 10.1002/Art.37801  0.573
2013 Ananthakrishnan AN, Gainer VS, Cai T, Cheng S, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw S, Churchill S, Karlson EW, Kohane I, Perlis R, Plenge RM, et al. 221 Psychiatric Co-Morbidity Is Associated With Increased Risk of Surgery in Crohns Disease Gastroenterology. 144: S-48. DOI: 10.1016/S0016-5085(13)60167-5  0.574
2013 Ananthakrishnan AN, Cagan A, Gainer VS, Cai T, Churchill S, Karlson EW, Kohane I, Plenge RM, Liao KP, Murphy SN. 1 Normalization of Vitamin D Status is Associated with Reduced Risk of Surgery and Hospitalization in Inflammatory Bowel Disease: A Prospective Study Gastroenterology. 144: S-1. DOI: 10.1016/S0016-5085(13)60001-3  0.302
2012 Biesecker LG, Burke W, Kohane I, Plon SE, Zimmern R. Next-generation sequencing in the clinic: are we ready? Nature Reviews. Genetics. 13: 818-24. PMID 23076269 DOI: 10.1038/Nrg3357  0.308
2012 Schmid PR, Palmer NP, Kohane IS, Berger B. Making sense out of massive data by going beyond differential expression. Proceedings of the National Academy of Sciences of the United States of America. 109: 5594-9. PMID 22447773 DOI: 10.1073/Pnas.1118792109  0.308
2012 Ananthakrishnan AN, Guzman-Perez R, Gainer V, Cai T, Churchill S, Kohane I, Plenge RM, Murphy S. Predictors of severe outcomes associated with Clostridium difficile infection in patients with inflammatory bowel disease Alimentary Pharmacology & Therapeutics. 35: 789-795. PMID 22360370 DOI: 10.1111/J.1365-2036.2012.05022.X  0.304
2011 Kohane IS, Szolovits P. Marco Ramoni: an appreciation of academic achievement. Journal of the American Medical Informatics Association : Jamia. 18: 367-9. PMID 21474623 DOI: 10.1136/Amiajnl-2011-000218  0.546
2011 Kurreeman F, Liao K, Chibnik L, Hickey B, Stahl E, Gainer V, Li G, Bry L, Mahan S, Ardlie K, Thomson B, Szolovits P, Churchill S, Murphy SN, Cai T, ... ... Kohane I, et al. Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records. American Journal of Human Genetics. 88: 57-69. PMID 21211616 DOI: 10.1016/J.Ajhg.2010.12.007  0.608
2011 Glass A, Taube S, McMurry A, Eddy C, Chance PL, McShane L, Polley M, Kohane I. C-C4-02: Using a Natural Language Processor to Remove All Elements of Personal Health Information (PHI) to Deidentify Clinical Annotations for the Specimen Retrieval System (SRS) Clinical Medicine & Research. 9: 170-170. DOI: 10.3121/Cmr.2011.1020.C-C4-02  0.343
2010 Liao KP, Cai T, Gainer V, Goryachev S, Zeng-treitler Q, Raychaudhuri S, Szolovits P, Churchill S, Murphy S, Kohane I, Karlson EW, Plenge RM. Electronic medical records for discovery research in rheumatoid arthritis. Arthritis Care & Research. 62: 1120-7. PMID 20235204 DOI: 10.1002/Acr.20184  0.602
2009 Murphy S, Churchill S, Bry L, Chueh H, Weiss S, Lazarus R, Zeng Q, Dubey A, Gainer V, Mendis M, Glaser J, Kohane I. Instrumenting the health care enterprise for discovery research in the genomic era. Genome Research. 19: 1675-81. PMID 19602638 DOI: 10.1101/Gr.094615.109  0.316
2009 Schraefel M, Jacobs R, André P, Kohane I, White R, La Dantec CA, Tan D, Mamykina L, Berners-Lee T, Marsden G, Consolvo S, Shneiderman B, Szolovits P, Weitzner D. Interacting with eHealth - Towards grand challenges for HCI Conference On Human Factors in Computing Systems - Proceedings. 3309-3312. DOI: 10.1145/1520340.1520476  0.525
2007 Levine M, Adida B, Mandl K, Kohane I, Halamka J. What are the benefits and risks of fitting patients with radiofrequency identification devices. Plos Medicine. 4: 1709-1711. PMID 18044979 DOI: 10.1371/Journal.Pmed.0040322  0.316
2007 Loscalzo J, Kohane I, Barabasi AL. Human disease classification in the postgenomic era: a complex systems approach to human pathobiology. Molecular Systems Biology. 3: 124. PMID 17625512 DOI: 10.1038/Msb4100163  0.304
2006 Sebastiani P, Mandl KD, Szolovits P, Kohane IS, Ramoni MF. A Bayesian dynamic model for influenza surveillance. Statistics in Medicine. 25: 1803-16; discussion . PMID 16645996 DOI: 10.1002/Sim.2566  0.501
2006 Butte AJ, Kohane IS. Creation and implications of a phenome-genome network. Nature Biotechnology. 24: 55-62. PMID 16404398 DOI: 10.1038/Nbt1150  0.442
2005 Wolfe CJ, Kohane IS, Butte AJ. Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks. Bmc Bioinformatics. 6: 227. PMID 16162296 DOI: 10.1186/1471-2105-6-227  0.42
2004 Kho AT, Zhao Q, Cai Z, Butte AJ, Kim JY, Pomeroy SL, Rowitch DH, Kohane IS. Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers. Genes & Development. 18: 629-40. PMID 15075291 DOI: 10.1101/Gad.1182504  0.394
2004 Allocco DJ, Kohane IS, Butte AJ. Quantifying the relationship between co-expression, co-regulation and gene function. Bmc Bioinformatics. 5: 18. PMID 15053845 DOI: 10.1186/1471-2105-5-18  0.408
2003 Patti ME, Butte AJ, Crunkhorn S, Cusi K, Berria R, Kashyap S, Miyazaki Y, Kohane I, Costello M, Saccone R, Landaker EJ, Goldfine AB, Mun E, DeFronzo R, Finlayson J, et al. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1. Proceedings of the National Academy of Sciences of the United States of America. 100: 8466-71. PMID 12832613 DOI: 10.1073/Pnas.1032913100  0.446
2003 Nimgaonkar A, Sanoudou D, Butte AJ, Haslett JN, Kunkel LM, Beggs AH, Kohane IS. Reproducibility of gene expression across generations of Affymetrix microarrays. Bmc Bioinformatics. 4: 27. PMID 12823866 DOI: 10.1186/1471-2105-4-27  0.412
2003 Lee K, Kohane IS, Butte AJ. PGAGENE: integrating quantitative gene-specific results from the NHLBI programs for genomic applications. Bioinformatics (Oxford, England). 19: 778-9. PMID 12691993 DOI: 10.1093/Bioinformatics/Btg066  0.433
2002 Park PJ, Butte AJ, Kohane IS. Comparing expression profiles of genes with similar promoter regions. Bioinformatics (Oxford, England). 18: 1576-84. PMID 12490441 DOI: 10.1093/Bioinformatics/18.12.1576  0.389
2002 Kuo WP, Jenssen TK, Butte AJ, Ohno-Machado L, Kohane IS. Analysis of matched mRNA measurements from two different microarray technologies. Bioinformatics (Oxford, England). 18: 405-12. PMID 11934739 DOI: 10.1093/Bioinformatics/18.3.405  0.389
2001 Butte AJ, Bao L, Reis BY, Watkins TW, Kohane IS. Comparing the similarity of time-series gene expression using signal processing metrics Journal of Biomedical Informatics. 34: 396-405. PMID 12198759 DOI: 10.1006/Jbin.2002.1037  0.407
2001 Riva A, Mandl KD, Oh DH, Nigrin DJ, Butte AJ, Szolovits P, Kohane IS. The personal internetworked notary and guardian. International Journal of Medical Informatics. 62: 27-40. PMID 11340004 DOI: 10.1016/S1386-5056(00)00136-2  0.651
2001 Mandl KD, Markwell D, MacDonald R, Szolovits P, Kohane IS. Public standards and patients' control: how to keep electronic medical records accessible but privateMedical information: access and privacyDoctrines for developing electronic medical recordsDesirable characteristics of electronic medical recordsChallenges and limitations for electronic medical recordsConclusionsCommentary: Open approaches to electronic patient recordsCommentary: A patient's viewpoint Bmj. 322: 283-287. PMID 11157533 DOI: 10.1136/Bmj.322.7281.283  0.577
2001 Butte AJ, Reis B, Kho A, Sun Y, Kohane IS. Analyzing functional genomic differences yields oncogenes and chromosomal breakpoints in ALL and AML Nature Genetics. 27: 45-45. DOI: 10.1038/87022  0.366
2000 Greenes DS, Fleisher GR, Kohane I. Potential impact of a computerized system to report late-arriving laboratory results in the emergency department. Pediatric Emergency Care. 16: 313-315. PMID 11063357 DOI: 10.1097/00006565-200010000-00002  0.319
2000 Butte AJ, Tamayo P, Slonim D, Golub TR, Kohane IS. Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks. Proceedings of the National Academy of Sciences of the United States of America. 97: 12182-6. PMID 11027309 DOI: 10.1073/Pnas.220392197  0.415
2000 Butte AJ, Kohane IS. Mutual information relevance networks: functional genomic clustering using pairwise entropy measurements. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 418-29. PMID 10902190 DOI: 10.1142/9789814447331_0040  0.427
1999 Butte AJ, Kohane IS. Using Cross-Validation to Find the Optimal Polynomial Model for Pediatric Anthropometric Time-Series Data Pediatric Research. 45: 86-86. DOI: 10.1203/00006450-199904020-00513  0.385
1999 Butte AJ, Kohane IS. Increasing Frequency of Diabetes Clinic Visits Is Associated with Improving Hemoglobin A1c Pediatric Research. 45: 86A-86A. DOI: 10.1203/00006450-199904020-00512  0.377
1999 Butte AJ, Kohane IS. The Relationship of Arm Span Vs. Height in Boys with Constitutional Delay and Boys and Girls with Short Stature Pediatric Research. 45: 86A-86A. DOI: 10.1203/00006450-199904020-00511  0.34
1998 Rind DM, Szolovits P, Kohane IS. Confidentiality and Electronic Medical Records Annals of Internal Medicine. 128: 510-511. DOI: 10.7326/0003-4819-128-6-199803150-00033  0.528
1997 Rind DM, Kohane IS, Szolovits P, Safran C, Chueh HC, Barnett GO. Maintaining the confidentiality of medical records shared over the Internet and the World Wide Web. Annals of Internal Medicine. 127: 138-41. PMID 9230004 DOI: 10.7326/0003-4819-127-2-199707150-00008  0.575
1996 Kohane IS, Greenspun P, Fackler JC, Cimino C, Szolovits P. Building National Electronic Medical Record Systems via the World Wide Web Journal of the American Medical Informatics Association. 3: 191-207. PMID 8723610 DOI: 10.1136/Jamia.1996.96310633  0.554
1996 Greenspun P, Fackler J, Cimino C, Szolovits P, Kohane I. Building national electronic medical record systems via the World Wide Web American Journal of Ophthalmology. 122: 465. DOI: 10.1016/S0002-9394(14)72101-4  0.573
1994 Szolovits P, Kohane I. Against Simple Universal Health-care Identifiers Journal of the American Medical Informatics Association. 1: 316-319. PMID 7719815 DOI: 10.1136/Jamia.1994.95236164  0.588
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