Kirk E. Lohmueller - Publications

Affiliations: 
Ecology and Evolutionary Biology University of California, Los Angeles, Los Angeles, CA 
Area:
Population genetics; Statistical methods in evolutionary and medical genetics; genetic variation data

85 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kyriazis CC, Lohmueller KE. Constraining models of dominance for nonsynonymous mutations in the human genome. Plos Genetics. 20: e1011198. PMID 39302992 DOI: 10.1371/journal.pgen.1011198  0.406
2024 Di C, Lohmueller KE. Revisiting Dominance in Population Genetics. Genome Biology and Evolution. 16. PMID 39114967 DOI: 10.1093/gbe/evae147  0.35
2024 Kyriazis CC, Serieys LEK, Bishop JM, Drouilly M, Viljoen S, Wayne RK, Lohmueller KE. The influence of gene flow on population viability in an isolated urban caracal population. Molecular Ecology. 33: e17346. PMID 38581173 DOI: 10.1111/mec.17346  0.372
2024 Kyriazis CC, Lohmueller KE. Constraining models of dominance for nonsynonymous mutations in the human genome. Biorxiv : the Preprint Server For Biology. PMID 38463985 DOI: 10.1101/2024.02.25.582010  0.419
2023 Kyriazis CC, Robinson JA, Lohmueller KE. Using Computational Simulations to Model Deleterious Variation and Genetic Load in Natural Populations. The American Naturalist. 202: 737-752. PMID 38033186 DOI: 10.1086/726736  0.396
2023 Mah JC, Lohmueller KE, Garud N. Inference of the demographic histories and selective effects of human gut commensal microbiota over the course of human history. Biorxiv : the Preprint Server For Biology. PMID 38014007 DOI: 10.1101/2023.11.09.566454  0.391
2023 Nigenda-Morales SF, Lin M, Nuñez-Valencia PG, Kyriazis CC, Beichman AC, Robinson JA, Ragsdale AP, Urbán R J, Archer FI, Viloria-Gómora L, Pérez-Álvarez MJ, Poulin E, Lohmueller KE, Moreno-Estrada A, Wayne RK. The genomic footprint of whaling and isolation in fin whale populations. Nature Communications. 14: 5465. PMID 37699896 DOI: 10.1038/s41467-023-40052-z  0.433
2023 Barroso GV, Lohmueller KE. Inferring the mode and strength of ongoing selection. Genome Research. PMID 37055196 DOI: 10.1101/gr.276386.121  0.452
2023 Kyriazis CC, Beichman AC, Brzeski KE, Hoy SR, Peterson RO, Vucetich JA, Vucetich LM, Lohmueller KE, Wayne RK. Genomic Underpinnings of Population Persistence in Isle Royale Moose. Molecular Biology and Evolution. 40. PMID 36729989 DOI: 10.1093/molbev/msad021  0.437
2023 Zhang X, Kim B, Singh A, Sankararaman S, Durvasula A, Lohmueller KE. MaLAdapt reveals novel targets of adaptive introgression from Neanderthals and Denisovans in worldwide human populations. Molecular Biology and Evolution. PMID 36617238 DOI: 10.1093/molbev/msad001  0.686
2023 Mooney JA, Marsden CD, Yohannes A, Wayne RK, Lohmueller KE. Long-term Small Population Size, Deleterious Variation, and Altitude Adaptation in the Ethiopian Wolf, a Severely Endangered Canid. Molecular Biology and Evolution. 40. PMID 36585842 DOI: 10.1093/molbev/msac277  0.432
2022 Robinson J, Kyriazis CC, Yuan SC, Lohmueller KE. Deleterious Variation in Natural Populations and Implications for Conservation Genetics. Annual Review of Animal Biosciences. PMID 36332644 DOI: 10.1146/annurev-animal-080522-093311  0.436
2022 Johri P, Eyre-Walker A, Gutenkunst RN, Lohmueller KE, Jensen JD. On the prospect of achieving accurate joint estimation of selection with population history. Genome Biology and Evolution. PMID 35675379 DOI: 10.1093/gbe/evac088  0.671
2022 Robinson JA, Kyriazis CC, Nigenda-Morales SF, Beichman AC, Rojas-Bracho L, Robertson KM, Fontaine MC, Wayne RK, Lohmueller KE, Taylor BL, Morin PA. The critically endangered vaquita is not doomed to extinction by inbreeding depression. Science (New York, N.Y.). 376: 635-639. PMID 35511971 DOI: 10.1126/science.abm1742  0.324
2022 Sork VL, Cokus SJ, Fitz-Gibbon ST, Zimin AV, Puiu D, Garcia JA, Gugger PF, Henriquez CL, Zhen Y, Lohmueller KE, Pellegrini M, Salzberg SL. High-quality genome and methylomes illustrate features underlying evolutionary success of oaks. Nature Communications. 13: 2047. PMID 35440538 DOI: 10.1038/s41467-022-29584-y  0.406
2022 Vecchyo DO, Lohmueller KE, Novembre J. Haplotype-based inference of the distribution of fitness effects. Genetics. PMID 35100400 DOI: 10.1093/genetics/iyac002  0.447
2021 Beichman AC, Kalhori P, Kyriazis CC, DeVries AA, Nigenda-Morales S, Heckel G, Schramm Y, Moreno-Estrada A, Kennett DJ, Hylkema M, Bodkin J, Koepfli KP, Lohmueller KE, Wayne RK. Genomic analyses reveal range-wide devastation of sea otter populations. Molecular Ecology. PMID 34967471 DOI: 10.1111/mec.16334  0.427
2021 Findley AS, Zhang X, Boye C, Lin YL, Kalita CA, Barreiro L, Lohmueller KE, Pique-Regi R, Luca F. A signature of Neanderthal introgression on molecular mechanisms of environmental responses. Plos Genetics. 17: e1009493. PMID 34570765 DOI: 10.1371/journal.pgen.1009493  0.636
2021 Garcia JA, Lohmueller KE. Negative linkage disequilibrium between amino acid changing variants reveals interference among deleterious mutations in the human genome. Plos Genetics. 17: e1009676. PMID 34319975 DOI: 10.1371/journal.pgen.1009676  0.508
2021 Mooney JA, Yohannes A, Lohmueller KE. The impact of identity by descent on fitness and disease in dogs. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33853941 DOI: 10.1073/pnas.2019116118  0.446
2021 Durvasula A, Lohmueller KE. Negative selection on complex traits limits phenotype prediction accuracy between populations. American Journal of Human Genetics. PMID 33691092 DOI: 10.1016/j.ajhg.2021.02.013  0.484
2021 Kyriazis CC, Wayne RK, Lohmueller KE. Strongly deleterious mutations are a primary determinant of extinction risk due to inbreeding depression. Evolution Letters. 5: 33-47. PMID 33552534 DOI: 10.1002/evl3.209  0.425
2020 Grujic O, Phung TN, Kwon SB, Arneson A, Lee Y, Lohmueller KE, Ernst J. Identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations. Nature Communications. 11: 6168. PMID 33268804 DOI: 10.1038/s41467-020-19962-9  0.305
2020 Adrion JR, Cole CB, Dukler N, Galloway JG, Gladstein AL, Gower G, Kyriazis CC, Ragsdale AP, Tsambos G, Baumdicker F, Carlson J, Cartwright RA, Durvasula A, Gronau I, Kim BY, ... ... Lohmueller KE, et al. A community-maintained standard library of population genetic models. Elife. 9. PMID 32573438 DOI: 10.7554/Elife.54967  0.438
2020 Zhang X, Kim B, Lohmueller KE, Huerta-Sánchez E. The Impact of Recessive Deleterious Variation on Signals of Adaptive Introgression in Human Populations. Genetics. PMID 32487519 DOI: 10.1534/Genetics.120.303081  0.79
2020 Huber CD, Kim BY, Lohmueller KE. Population genetic models of GERP scores suggest pervasive turnover of constrained sites across mammalian evolution. Plos Genetics. 16: e1008827. PMID 32469868 DOI: 10.1371/Journal.Pgen.1008827  0.499
2020 Adrion JR, Cole CB, Dukler N, Galloway JG, Gladstein AL, Gower G, Kyriazis CC, Ragsdale AP, Tsambos G, Baumdicker F, Carlson J, Cartwright RA, Durvasula A, Gronau I, Kim BY, ... ... Lohmueller KE, et al. Author response: A community-maintained standard library of population genetic models Elife. DOI: 10.7554/Elife.54967.Sa2  0.406
2019 Buckleton JS, Lohmueller KE, Inman K, Cheng K, Curran JM, Pugh SN, Bright JA, Taylor DA. Testing whether stutter and low-level DNA peaks are additive. Forensic Science International. Genetics. 43: 102166. PMID 31586815 DOI: 10.1016/J.Fsigen.2019.102166  0.348
2019 Beichman AC, Koepfli KP, Li G, Murphy W, Dobrynin P, Kilver S, Tinker MT, Murray MJ, Johnson J, Lindblad-Toh K, Karlsson EK, Lohmueller KE, Wayne RK. Aquatic adaptation and depleted diversity: a deep dive into the genomes of the sea otter and giant otter. Molecular Biology and Evolution. PMID 31212313 DOI: 10.1093/Molbev/Msz101  0.476
2019 Robinson JA, Räikkönen J, Vucetich LM, Vucetich JA, Peterson RO, Lohmueller KE, Wayne RK. Genomic signatures of extensive inbreeding in Isle Royale wolves, a population on the threshold of extinction. Science Advances. 5: eaau0757. PMID 31149628 DOI: 10.1126/Sciadv.Aau0757  0.549
2019 Phung TN, Wayne RK, Wilson MA, Lohmueller KE. Complex patterns of sex-biased demography in canines. Proceedings. Biological Sciences. 286: 20181976. PMID 31113325 DOI: 10.1098/Rspb.2018.1976  0.378
2018 vonHoldt BM, Kartzinel RY, Huber CD, Le Underwood V, Zhen Y, Ruegg K, Lohmueller KE, Smith TB. Growth factor gene IGF1 is associated with bill size in the black-bellied seedcracker Pyrenestes ostrinus. Nature Communications. 9: 4855. PMID 30451848 DOI: 10.1038/S41467-018-07374-9  0.486
2018 Robinson JA, Brown C, Kim BY, Lohmueller KE, Wayne RK. Purging of Strongly Deleterious Mutations Explains Long-Term Persistence and Absence of Inbreeding Depression in Island Foxes. Current Biology : Cb. 28: 3487-3494.e4. PMID 30415705 DOI: 10.1016/J.Cub.2018.08.066  0.543
2018 Mooney JA, Huber CD, Service S, Sul JH, Marsden CD, Zhang Z, Sabatti C, Ruiz-Linares A, Bedoya G, Freimer N, Lohmueller KE. Understanding the Hidden Complexity of Latin American Population Isolates. American Journal of Human Genetics. 103: 707-726. PMID 30401458 DOI: 10.1016/J.Ajhg.2018.09.013  0.504
2018 Kim BY, Huber CD, Lohmueller KE. Deleterious variation shapes the genomic landscape of introgression. Plos Genetics. 14: e1007741. PMID 30346959 DOI: 10.1371/Journal.Pgen.1007741  0.555
2018 Kim BY, Xinzeng W, Fitz-Gibbon S, Lohmueller KE, Ortego J, Gugger PF, Sork VL. RADseq data reveal ancient, but not pervasive, introgression between Californian tree and scrub oak species (Quercus sect. Quercus: Fagaceae). Molecular Ecology. PMID 30226013 DOI: 10.1111/Mec.14869  0.325
2018 Chiang CWK, Marcus JH, Sidore C, Biddanda A, Al-Asadi H, Zoledziewska M, Pitzalis M, Busonero F, Maschio A, Pistis G, Steri M, Angius A, Lohmueller KE, Abecasis GR, Schlessinger D, et al. Genomic history of the Sardinian population. Nature Genetics. PMID 30224645 DOI: 10.1038/S41588-018-0215-8  0.576
2018 Huber CD, Durvasula A, Hancock AM, Lohmueller KE. Gene expression drives the evolution of dominance. Nature Communications. 9: 2750. PMID 30013096 DOI: 10.1038/S41467-018-05281-7  0.462
2018 Schweizer RM, Durvasula A, Smith J, Vohr SH, Stahler DR, Galaverni M, Thalmann O, Smith DW, Randi E, Ostrander EA, Green RE, Lohmueller KE, Novembre J, Wayne RK. Natural Selection and Origin of a Melanistic Allele in North American Gray Wolves. Molecular Biology and Evolution. 35: 1190-1209. PMID 29688543 DOI: 10.1093/Molbev/Msy031  0.547
2018 Beichman AC, Huerta-Sanchez E, Lohmueller KE. Using Genomic Data to Infer Historic Population Dynamics of Nonmodel Organisms Annual Review of Ecology, Evolution, and Systematics. 49: 433-456. DOI: 10.1146/Annurev-Ecolsys-110617-062431  0.72
2017 Beichman AC, Phung TN, Lohmueller KE. Comparison of Single Genome and Allele Frequency Data Reveals Discordant Demographic Histories. G3 (Bethesda, Md.). PMID 28893846 DOI: 10.1534/G3.117.300259  0.537
2017 Zhen Y, Harrigan RJ, Ruegg KC, Anderson EC, Ng TC, Lao S, Lohmueller KE, Smith TB. Genomic divergence across ecological gradients in the Central African rainforest songbird (Andropadus virens). Molecular Ecology. PMID 28752944 DOI: 10.1111/Mec.14270  0.58
2017 Huber CD, Kim BY, Marsden CD, Lohmueller KE. Determining the factors driving selective effects of new nonsynonymous mutations. Proceedings of the National Academy of Sciences of the United States of America. PMID 28400513 DOI: 10.1073/Pnas.1619508114  0.512
2017 Kim BY, Huber CD, Lohmueller KE. Inference of the Distribution of Selection Coefficients for New Nonsynonymous Mutations Using Large Samples. Genetics. PMID 28249985 DOI: 10.1534/Genetics.116.197145  0.417
2017 Pedersen CT, Lohmueller KE, Grarup N, Bjerregaard P, Hansen T, Siegismund HR, Moltke I, Albrechtsen A. The Effect of an Extreme and Prolonged Population Bottleneck on Patterns of Deleterious Variation: Insights from the Greenlandic Inuit. Genetics. 205: 787-801. PMID 27903613 DOI: 10.1534/Genetics.116.193821  0.535
2016 Phung TN, Huber CD, Lohmueller KE. Determining the Effect of Natural Selection on Linked Neutral Divergence across Species. Plos Genetics. 12: e1006199. PMID 27508305 DOI: 10.1371/Journal.Pgen.1006199  0.493
2016 Ortega-Del Vecchyo D, Marsden CD, Lohmueller KE. PReFerSim: Fast simulation of demography and selection under the Poisson Random Field model. Bioinformatics (Oxford, England). PMID 27436562 DOI: 10.1093/Bioinformatics/Btw478  0.47
2016 Robinson JA, Ortega-Del Vecchyo D, Fan Z, Kim BY, vonHoldt BM, Marsden CD, Lohmueller KE, Wayne RK. Genomic Flatlining in the Endangered Island Fox. Current Biology : Cb. PMID 27112291 DOI: 10.1016/J.Cub.2016.02.062  0.579
2016 Marsden CD, Rudin N, Inman K, Lohmueller KE. An assessment of the information content of likelihood ratios derived from complex mixtures. Forensic Science International. Genetics. 22: 64-72. PMID 26851613 DOI: 10.1016/J.Fsigen.2016.01.008  0.323
2016 Freedman AH, Lohmueller KE, Wayne RK. Evolutionary History, Selective Sweeps, and Deleterious Variation in the Dog Annual Review of Ecology, Evolution, and Systematics. 47: 73-96. DOI: 10.1146/Annurev-Ecolsys-121415-032155  0.553
2015 Marsden CD, Ortega-Del Vecchyo D, O'Brien DP, Taylor JF, Ramirez O, Vilà C, Marques-Bonet T, Schnabel RD, Wayne RK, Lohmueller KE. Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs. Proceedings of the National Academy of Sciences of the United States of America. PMID 26699508 DOI: 10.1073/Pnas.1512501113  0.598
2015 Zoledziewska M, Sidore C, Chiang CW, Sanna S, Mulas A, Steri M, Busonero F, Marcus JH, Marongiu M, Maschio A, Del Vecchyo DO, Floris M, Meloni A, Delitala A, Concas MP, ... ... Lohmueller KE, et al. Height-reducing variants and selection for short stature in Sardinia. Nature Genetics. PMID 26366551 DOI: 10.1038/Ng.3403  0.483
2015 Rohlfs RV, Aguiar VR, Lohmueller KE, Castro AM, Ferreira AC, Almeida VC, Louro ID, Nielsen R. Fitting the Balding-Nichols model to forensic databases. Forensic Science International. Genetics. 19: 86-91. PMID 26186694 DOI: 10.1016/J.Fsigen.2015.05.005  0.431
2015 Brown R, Lee H, Eskin A, Kichaev G, Lohmueller KE, Reversade B, Nelson SF, Pasaniuc B. Leveraging ancestry to improve causal variant identification in exome sequencing for monogenic disorders. European Journal of Human Genetics : Ejhg. PMID 25898925 DOI: 10.1038/Ejhg.2015.68  0.426
2015 Kim BY, Lohmueller KE. Selection and reduced population size cannot explain higher amounts of Neandertal ancestry in East Asian than in European human populations. American Journal of Human Genetics. 96: 454-61. PMID 25683122 DOI: 10.1016/J.Ajhg.2014.12.029  0.494
2014 Lohmueller KE. The distribution of deleterious genetic variation in human populations. Current Opinion in Genetics & Development. 29: 139-46. PMID 25461617 DOI: 10.1016/J.Gde.2014.09.005  0.59
2014 Lohmueller KE. Evolution. On the origin of Peter Rabbit. Science (New York, N.Y.). 345: 1000-1. PMID 25170135 DOI: 10.1126/Science.1258775  0.548
2014 DeGiorgio M, Lohmueller KE, Nielsen R. A model-based approach for identifying signatures of ancient balancing selection in genetic data. Plos Genetics. 10: e1004561. PMID 25144706 DOI: 10.1371/Journal.Pgen.1004561  0.471
2014 Ko A, Cantor RM, Weissglas-Volkov D, Nikkola E, Reddy PM, Sinsheimer JS, Pasaniuc B, Brown R, Alvarez M, Rodriguez A, Rodriguez-Guillen R, Bautista IC, Arellano-Campos O, Muñoz-Hernández LL, Salomaa V, ... ... Lohmueller KE, et al. Amerindian-specific regions under positive selection harbour new lipid variants in Latinos. Nature Communications. 5: 3983. PMID 24886709 DOI: 10.1038/Ncomms4983  0.439
2014 Lohmueller KE. The impact of population demography and selection on the genetic architecture of complex traits. Plos Genetics. 10: e1004379. PMID 24875776 DOI: 10.1371/Journal.Pgen.1004379  0.575
2014 Lohmueller KE, Rudin N, Inman K. Analysis of allelic drop-out using the Identifiler(®) and PowerPlex(®) 16 forensic STR typing systems. Forensic Science International. Genetics. 12: 1-11. PMID 24841801 DOI: 10.1016/J.Fsigen.2014.04.003  0.326
2014 Wilson Sayres MA, Lohmueller KE, Nielsen R. Natural Selection Reduced Diversity on Human Y Chromosomes Plos Genetics. 10. PMID 24415951 DOI: 10.1371/Journal.Pgen.1004064  0.445
2014 Lohmueller KE, Sparsø T, Li Q, Andersson E, Korneliussen T, Albrechtsen A, Banasik K, Grarup N, Hallgrimsdottir I, Kiil K, Kilpeläinen TO, Krarup NT, Pers TH, Sanchez G, Hu Y, et al. Erratum: Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes (The American Journal of Human Genetics (2013) 93 (1072-1086)) American Journal of Human Genetics. 94. DOI: 10.1016/J.Ajhg.2014.02.002  0.388
2013 Lohmueller KE, Sparsø T, Li Q, Andersson E, Korneliussen T, Albrechtsen A, Banasik K, Grarup N, Hallgrimsdottir I, Kiil K, Kilpeläinen TO, Krarup NT, Pers TH, Sanchez G, Hu Y, et al. Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes. American Journal of Human Genetics. 93: 1072-86. PMID 24290377 DOI: 10.1016/J.Ajhg.2013.11.005  0.338
2011 Lohmueller KE, Albrechtsen A, Li Y, Kim SY, Korneliussen T, Vinckenbosch N, Tian G, Huerta-Sanchez E, Feder AF, Grarup N, Jørgensen T, Jiang T, Witte DR, Sandbæk A, Hellmann I, et al. Natural selection affects multiple aspects of genetic variation at putatively neutral sites across the human genome. Plos Genetics. 7: e1002326. PMID 22022285 DOI: 10.1371/Journal.Pgen.1002326  0.776
2011 Rasmussen M, Guo X, Wang Y, Lohmueller KE, Rasmussen S, Albrechtsen A, Skotte L, Lindgreen S, Metspalu M, Jombart T, Kivisild T, Zhai W, Eriksson A, Manica A, Orlando L, et al. An Aboriginal Australian genome reveals separate human dispersals into Asia. Science (New York, N.Y.). 334: 94-8. PMID 21940856 DOI: 10.1126/Science.1211177  0.584
2011 Kim SY, Lohmueller KE, Albrechtsen A, Li Y, Korneliussen T, Tian G, Grarup N, Jiang T, Andersen G, Witte D, Jorgensen T, Hansen T, Pedersen O, Wang J, Nielsen R. Estimation of allele frequency and association mapping using next-generation sequencing data. Bmc Bioinformatics. 12: 231. PMID 21663684 DOI: 10.1186/1471-2105-12-231  0.403
2011 Lohmueller KE, Bustamante CD, Clark AG. Detecting directional selection in the presence of recent admixture in African-Americans. Genetics. 187: 823-35. PMID 21196524 DOI: 10.1534/Genetics.110.122739  0.666
2010 Boyko AR, Quignon P, Li L, Schoenebeck JJ, Degenhardt JD, Lohmueller KE, Zhao K, Brisbin A, Parker HG, vonHoldt BM, Cargill M, Auton A, Reynolds A, Elkahloun AG, Castelhano M, et al. A simple genetic architecture underlies morphological variation in dogs. Plos Biology. 8: e1000451. PMID 20711490 DOI: 10.1371/Journal.Pbio.1000451  0.767
2010 Lohmueller KE, Degenhardt JD, Keinan A. Sex-averaged recombination and mutation rates on the X chromosome: a comment on Labuda et al. American Journal of Human Genetics. 86: 978-80; author reply. PMID 20541048 DOI: 10.1016/J.Ajhg.2010.03.021  0.687
2010 Lohmueller KE. Graydon et al. provide no new evidence that forensic STR loci are functional. Forensic Science International. Genetics. 4: 273-4. PMID 20457048 DOI: 10.1016/J.Fsigen.2009.09.006  0.417
2010 Lohmueller KE, Bustamante CD, Clark AG. The effect of recent admixture on inference of ancient human population history. Genetics. 185: 611-22. PMID 20382834 DOI: 10.1534/Genetics.109.113761  0.71
2010 Vonholdt BM, Pollinger JP, Lohmueller KE, Han E, Parker HG, Quignon P, Degenhardt JD, Boyko AR, Earl DA, Auton A, Reynolds A, Bryc K, Brisbin A, Knowles JC, Mosher DS, et al. Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication. Nature. 464: 898-902. PMID 20237475 DOI: 10.1038/Nature08837  0.782
2009 Wall JD, Lohmueller KE, Plagnol V. Detecting ancient admixture and estimating demographic parameters in multiple human populations. Molecular Biology and Evolution. 26: 1823-7. PMID 19420049 DOI: 10.1093/Molbev/Msp096  0.475
2009 Lohmueller KE, Bustamante CD, Clark AG. Methods for human demographic inference using haplotype patterns from genomewide single-nucleotide polymorphism data. Genetics. 182: 217-31. PMID 19255370 DOI: 10.1534/Genetics.108.099275  0.668
2009 Auton A, Bryc K, Boyko AR, Lohmueller KE, Novembre J, Reynolds A, Indap A, Wright MH, Degenhardt JD, Gutenkunst RN, King KS, Nelson MR, Bustamante CD. Global distribution of genomic diversity underscores rich complex history of continental human populations Genome Research. 19: 795-803. PMID 19218534 DOI: 10.1101/Gr.088898.108  0.76
2008 Boyko AR, Williamson SH, Indap AR, Degenhardt JD, Hernandez RD, Lohmueller KE, Adams MD, Schmidt S, Sninsky JJ, Sunyaev SR, White TJ, Nielsen R, Clark AG, Bustamante CD. Assessing the evolutionary impact of amino acid mutations in the human genome. Plos Genetics. 4: e1000083. PMID 18516229 DOI: 10.1371/Journal.Pgen.1000083  0.794
2008 Lohmueller KE, Indap AR, Schmidt S, Boyko AR, Hernandez RD, Hubisz MJ, Sninsky JJ, White TJ, Sunyaev SR, Nielsen R, Clark AG, Bustamante CD. Proportionally more deleterious genetic variation in European than in African populations. Nature. 451: 994-7. PMID 18288194 DOI: 10.1038/Nature06611  0.763
2008 Olshen AB, Gold B, Lohmueller KE, Struewing JP, Satagopan J, Stefanov SA, Eskin E, Kirchhoff T, Lautenberger JA, Klein RJ, Friedman E, Norton L, Ellis NA, Viale A, Lee CS, et al. Analysis of genetic variation in Ashkenazi Jews by high density SNP genotyping. Bmc Genetics. 9: 14. PMID 18251999 DOI: 10.1186/1471-2156-9-14  0.626
2006 Lohmueller KE, Wong LJC, Mauney MM, Jiang L, Felder RA, Jose PA, Williams SM. Patterns of genetic variation in the hypertension candidate gene GRK4: Ethnic variation and haplotype structure Annals of Human Genetics. 70: 27-41. PMID 16441255 DOI: 10.1111/J.1529-8817.2005.00197.X  0.563
2006 Lohmueller KE, Mauney MM, Reich D, Braverman JM. Variants associated with common disease are not unusually differentiated in frequency across populations. American Journal of Human Genetics. 78: 130-6. PMID 16385456 DOI: 10.1086/499287  0.503
2004 Patterson N, Hattangadi N, Lane B, Lohmueller KE, Hafler DA, Oksenberg JR, Hauser SL, Smith MW, O'Brien SJ, Altshuler D, Daly MJ, Reich D. Methods for high-density admixture mapping of disease genes. American Journal of Human Genetics. 74: 979-1000. PMID 15088269 DOI: 10.1086/420871  0.471
2003 Lohmueller KE, Pearce CL, Pike M, Lander ES, Hirschhorn JN. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nature Genetics. 33: 177-82. PMID 12524541 DOI: 10.1038/Ng1071  0.466
2002 Hirschhorn JN, Lohmueller K, Byrne E, Hirschhorn K. A comprehensive review of genetic association studies. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 4: 45-61. PMID 11882781 DOI: 10.1097/00125817-200203000-00002  0.35
2002 Hirschhorn JN, Lohmueller K, Byrne E, Hirschhorn K. A comprehensive review of genetic association studies. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 4: 45-61. PMID 11882781 DOI: 10.1097/00125817-200203000-00002  0.35
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