Wai-keung Leung, Ph.D. - Publications

Affiliations: 
2001 The Chinese University of Hong Kong, Hong Kong, Hong Kong 
Area:
Medicine and Surgery, Epidemiology

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ooi CJ, Hilmi I, Banerjee R, Chuah SW, Ng SC, Wei SC, Makharia GK, Pisespongsa P, Chen MH, Ran ZH, Ye BD, Park DI, Ling KL, Ong D, Ahuja V, ... ... Leung WK, et al. Best practices on immunomodulators and biologic agents for ulcerative colitis and Crohn's disease in Asia. Intestinal Research. PMID 31146509 DOI: 10.5217/Ir.2019.00026  0.455
2016 Ng SC, Leung WK, Shi HY, Li MK, Leung CM, Ng CK, Lo FH, Hui YT, Tsang SW, Chan YK, Loo CK, Chan KH, Hui AJ, Chow WH, Harbord M, et al. Epidemiology of Inflammatory Bowel Disease from 1981 to 2014: Results from a Territory-Wide Population-Based Registry in Hong Kong. Inflammatory Bowel Diseases. PMID 27416041 DOI: 10.1097/MIB.0000000000000846  0.355
2016 Shi HY, Chan FK, Leung WK, Li MK, Leung CM, Sze SF, Ching JY, Lo FH, Tsang SW, Shan EH, Mak LY, Lam BC, Hui AJ, Chow WH, Wong MT, et al. Low-dose azathioprine is effective in maintaining remission in steroid-dependent ulcerative colitis: results from a territory-wide Chinese population-based IBD registry. Therapeutic Advances in Gastroenterology. 9: 449-56. PMID 27366213 DOI: 10.1177/1756283X16643509  0.34
2016 Liu KS, Wong IO, Leung WK. Helicobacter pylori associated gastric intestinal metaplasia: Treatment and surveillance. World Journal of Gastroenterology. 22: 1311-20. PMID 26811668 DOI: 10.3748/wjg.v22.i3.1311  0.302
2015 Shi HY, Chan FK, Leung WK, Li MK, Leung CM, Sze SF, Ching JY, Lo FH, Tsang SW, Shan EH, Mak LY, Lam BC, Hui AJ, Wong SH, Wong MT, et al. Natural History of Elderly-onset Ulcerative Colitis: Results from a Territory-wide Inflammatory Bowel Disease Registry. Journal of Crohn's & Colitis. PMID 26512132 DOI: 10.1093/ecco-jcc/jjv194  0.391
2015 Ooi CJ, Hilmi I, Makharia GK, Gibson PR, Fock KM, Ahuja V, Ling KL, Lim WC, Thia KT, Wei SC, Leung WK, Koh PK, Gearry RB, Goh KL, Ouyang Q, et al. The Asia Pacific Consensus Statements on Crohn's Disease Part 2: Management. Journal of Gastroenterology and Hepatology. PMID 25819311 DOI: 10.1111/jgh.12958  0.531
2015 Ooi CJ, Hilmi I, Makharia GK, Gibson PR, Fock KM, Ahuja V, Ling KL, Lim WC, Thia KT, Wei SC, Leung WK, Koh PK, Gearry RB, Goh KL, Ouyang Q, et al. The Asia Pacific Consensus Statements on Crohn's Disease Part 1: definition, diagnosis and epidemiology. Journal of Gastroenterology and Hepatology. PMID 25819140 DOI: 10.1111/jgh.12956  0.54
2013 Ng SC, Lau JY, Chan FK, Suen BY, Leung WK, Tse YK, Ng SS, Lee JF, To KF, Wu JC, Sung JJ. Increased risk of advanced neoplasms among asymptomatic siblings of patients with colorectal cancer. Gastroenterology. 144: 544-50. PMID 23159367 DOI: 10.1053/J.Gastro.2012.11.011  0.391
2012 Leung WK, Ho SS, Suen BY, Lai LH, Yu S, Ng EK, Ng SS, Chiu PW, Sung JJ, Chan FK, Lau JY. Capsule endoscopy or angiography in patients with acute overt obscure gastrointestinal bleeding: a prospective randomized study with long-term follow-up. The American Journal of Gastroenterology. 107: 1370-6. PMID 22825363 DOI: 10.1038/ajg.2012.212  0.385
2011 Shin VY, Jin HC, Ng EK, Cho CH, Leung WK, Sung JJ, Chu KM. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone promoted gastric cancer growth through prostaglandin E receptor (EP2 and EP4) in vivo and in vitro. Cancer Science. 102: 926-33. PMID 21261791 DOI: 10.1111/j.1349-7006.2011.01885.x  0.358
2010 Ooi CJ, Fock KM, Makharia GK, Goh KL, Ling KL, Hilmi I, Lim WC, Kelvin T, Gibson PR, Gearry RB, Ouyang Q, Sollano J, Manatsathit S, Rerknimitr R, Wei SC, ... Leung WK, et al. The Asia-Pacific consensus on ulcerative colitis. Journal of Gastroenterology and Hepatology. 25: 453-68. PMID 20370724 DOI: 10.1111/J.1440-1746.2010.06241.X  0.486
2009 Li J, Ng EK, Ng YP, Wong CY, Yu J, Jin H, Cheng VY, Go MY, Cheung PK, Ebert MP, Tong J, To KF, Chan FK, Sung JJ, Ip NY, ... Leung WK, et al. Identification of retinoic acid-regulated nuclear matrix-associated protein as a novel regulator of gastric cancer. British Journal of Cancer. 101: 691-8. PMID 19672268 DOI: 10.1038/Sj.Bjc.6605202  0.398
2009 Leung WK, Lau JY, Suen BY, Wong GL, Chow DK, Lai LH, To KF, Yim CK, Lee ES, Tsoi KK, Ng SS, Sung JJ. Repeat-screening colonoscopy 5 years after normal baseline-screening colonoscopy in average-risk Chinese: a prospective study. The American Journal of Gastroenterology. 104: 2028-34. PMID 19455125 DOI: 10.1038/ajg.2009.202  0.325
2009 Chow DK, Leong RW, Tsoi KK, Ng SS, Leung WK, Wu JC, Wong VW, Chan FK, Sung JJ. Long-term follow-up of ulcerative colitis in the Chinese population. The American Journal of Gastroenterology. 104: 647-54. PMID 19262521 DOI: 10.1038/ajg.2008.74  0.553
2009 Lee YT, Lai LH, Hui AJ, Wong VW, Ching JY, Wong GL, Wu JC, Chan HL, Leung WK, Lau JY, Sung JJ, Chan FK. Efficacy of cap-assisted colonoscopy in comparison with regular colonoscopy: a randomized controlled trial. The American Journal of Gastroenterology. 104: 41-6. PMID 19098847 DOI: 10.1038/Ajg.2008.56  0.544
2009 Chiu PW, Ng EK, Cheung FK, Chan FK, Leung WK, Wu JC, Wong VW, Yung MY, Tsoi K, Lau JY, Sung JJ, Chung SS. Predicting mortality in patients with bleeding peptic ulcers after therapeutic endoscopy. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 7: 311-6; quiz 253. PMID 18955161 DOI: 10.1016/j.cgh.2008.08.044  0.374
2008 Cheng YY, Jin H, Liu X, Siu JM, Wong YP, Ng EK, Yu J, Leung WK, Sung JJ, Chan FK. Fibulin 1 is downregulated through promoter hypermethylation in gastric cancer. British Journal of Cancer. 99: 2083-7. PMID 18985039 DOI: 10.1038/Sj.Bjc.6604760  0.402
2008 Chen BL, Yu J, Zeng ZR, Chu WK, Wong CY, Cheng YY, Sung JJ, Hu PJ, Leung WK. Rosiglitazone suppresses gastric carcinogenesis by up-regulating HCaRG expression. Oncology Reports. 20: 1093-7. PMID 18949406  0.397
2008 Shin VY, Jin HC, Ng EK, Yu J, Leung WK, Cho CH, Sung JJ. Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways. Toxicology and Applied Pharmacology. 233: 254-61. PMID 18805435 DOI: 10.1016/J.Taap.2008.08.012  0.33
2008 Leung WK, Wu KC, Wong CY, Cheng AS, Ching AK, Chan AW, Chong WW, Go MY, Yu J, To KF, Wang X, Chui YL, Fan DM, Sung JJ. Transgenic cyclooxygenase-2 expression and high salt enhanced susceptibility to chemical-induced gastric cancer development in mice. Carcinogenesis. 29: 1648-54. PMID 18611916 DOI: 10.1093/Carcin/Bgn156  0.399
2008 Leung WK, Wu MS, Kakugawa Y, Kim JJ, Yeoh KG, Goh KL, Wu KC, Wu DC, Sollano J, Kachintorn U, Gotoda T, Lin JT, You WC, Ng EK, Sung JJ, et al. Screening for gastric cancer in Asia: current evidence and practice. The Lancet. Oncology. 9: 279-87. PMID 18308253 DOI: 10.1016/S1470-2045(08)70072-X  0.41
2008 Lee YT, Chan FK, Leung WK, Chan HL, Wu JC, Yung MY, Ng EK, Lau JY, Sung JJ. Comparison of EUS and ERCP in the investigation with suspected biliary obstruction caused by choledocholithiasis: a randomized study. Gastrointestinal Endoscopy. 67: 660-8. PMID 18155205 DOI: 10.1016/J.Gie.2007.07.025  0.569
2008 Chow DK, Leong RW, Lai LH, Wong GL, Leung WK, Chan FK, Sung JJ. Changes in Crohn's disease phenotype over time in the Chinese population: validation of the Montreal classification system. Inflammatory Bowel Diseases. 14: 536-41. PMID 18058793 DOI: 10.1002/ibd.20335  0.533
2007 Lee N, Chan MC, Wong B, Choi KW, Sin W, Lui G, Chan PK, Lai RW, Cockram CS, Sung JJ, Leung WK. Fecal viral concentration and diarrhea in norovirus gastroenteritis. Emerging Infectious Diseases. 13: 1399-401. PMID 18252121 DOI: 10.3201/eid1309.061535  0.314
2007 Chan MW, Wong CY, Cheng AS, Chan VY, Chan KK, To KF, Chan FK, Sung JJ, Leung WK. Targeted inhibition of COX-2 expression by RNA interference suppresses tumor growth and potentiates chemosensitivity to cisplatin in human gastric cancer cells. Oncology Reports. 18: 1557-62. PMID 17982644  0.388
2007 Lai LH, Wong GL, Lau JY, Sung JJ, Leung WK. Initial experience of real-time capsule endoscopy in monitoring progress of the videocapsule through the upper GI tract. Gastrointestinal Endoscopy. 66: 1211-4. PMID 17945224 DOI: 10.1016/j.gie.2007.04.011  0.393
2007 Cheng YY, Yu J, Wong YP, Man EP, To KF, Jin VX, Li J, Tao Q, Sung JJ, Chan FK, Leung WK. Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer. British Journal of Cancer. 97: 895-901. PMID 17848950 DOI: 10.1038/Sj.Bjc.6603968  0.404
2007 Leung WK, Wu JC, Chan FK, Fung SS, Wong VW, Hui AJ, Hung LC, Sung JJ. Initial treatment with lansoprazole in young dyspeptic patients with negative urea breath test result: a randomized controlled trial with 12-month follow-up. The American Journal of Gastroenterology. 102: 1483-8. PMID 17593161 DOI: 10.1111/j.1572-0241.2007.01229.x  0.443
2007 Byeon JS, Yang SK, Kim TI, Kim WH, Lau JY, Leung WK, Fujita R, Makharia GK, Abdullah M, Hilmi I, Sollano J, Yeoh KG, Wu DC, Chen MH, Kongkam P, et al. Colorectal neoplasm in asymptomatic Asians: a prospective multinational multicenter colonoscopy survey. Gastrointestinal Endoscopy. 65: 1015-22. PMID 17531636 DOI: 10.1016/j.gie.2006.12.065  0.38
2007 Chan FK, Wong VW, Suen BY, Wu JC, Ching JY, Hung LC, Hui AJ, Leung VK, Lee VW, Lai LH, Wong GL, Chow DK, To KF, Leung WK, Chiu PW, et al. Combination of a cyclo-oxygenase-2 inhibitor and a proton-pump inhibitor for prevention of recurrent ulcer bleeding in patients at very high risk: a double-blind, randomised trial. Lancet (London, England). 369: 1621-6. PMID 17499604 DOI: 10.1016/S0140-6736(07)60749-1  0.586
2007 Ren TH, Wu J, Yew D, Ziea E, Lao L, Leung WK, Berman B, Hu PJ, Sung JJ. Effects of neonatal maternal separation on neurochemical and sensory response to colonic distension in a rat model of irritable bowel syndrome. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G849-56. PMID 17110521 DOI: 10.1152/Ajpgi.00400.2006  0.363
2007 Sung J, Wu J, Leung VK, Suen B, Lam PP, Lee Y, Chiu PW, Leung W, Ng EK, Chan FK, Lau JY. Randomized Comparison of a Novel Hemostatic Clip (Resolution Clip™) to Combined Epinephrine Injection and Heater Probe (HP) Thermocoagulation in Endoscopic Control of Peptic Ulcer Bleeding (PUB) Gastrointestinal Endoscopy. 65: AB156. DOI: 10.1016/J.Gie.2007.03.231  0.434
2006 Hui AY, Leung WK, Chan HL, Chan FK, Go MY, Chan KK, Tang BD, Chu ES, Sung JJ. Effect of celecoxib on experimental liver fibrosis in rat. Liver International : Official Journal of the International Association For the Study of the Liver. 26: 125-36. PMID 16420518 DOI: 10.1111/j.1478-3231.2005.01202.x  0.302
2006 Kim TI, Kim WH, Byeon J, Yang S, Leung W, Sung JJ, Lau J, Kim JY, Kim HJ, Yeoh K, Ho K, Wong RK, Abdullah M, Hilmi I, Goh K, et al. A Prospective Study of the Prevalence and Distribution of Colorectal Neoplasia in Asymptomatic Asian Population Gastrointestinal Endoscopy. 63: AB214. DOI: 10.1016/J.Gie.2006.03.531  0.4
2005 Jin Y, Leung WK, Sung JJ, Wu JR. p53-independent pRB degradation contributes to a drug-induced apoptosis in AGS cells. Cell Research. 15: 695-703. PMID 16212876 DOI: 10.1038/Sj.Cr.7290339  0.361
2005 Li Y, Jiang ZZ, Chen HX, Leung WK, Sung JJ, Ma WJ. The existence of a putative regulatory element in 3'-untranslated region of proto-oncogene HOX11's mRNA. Journal of Biochemistry and Molecular Biology. 38: 500-6. PMID 16053719 DOI: 10.5483/Bmbrep.2005.38.4.500  0.376
2005 Hung LC, Ching JY, Sung JJ, To KF, Hui AJ, Wong VW, Leong RW, Chan HL, Wu JC, Leung WK, Lee YT, Chung SC, Chan FK. Long-term outcome of Helicobacter pylori-negative idiopathic bleeding ulcers: a prospective cohort study. Gastroenterology. 128: 1845-50. PMID 15940620 DOI: 10.1053/J.Gastro.2005.03.026  0.695
2005 Chan HL, Kwan AC, To KF, Lai ST, Chan PK, Leung WK, Lee N, Wu A, Sung JJ. Clinical significance of hepatic derangement in severe acute respiratory syndrome. World Journal of Gastroenterology : Wjg. 11: 2148-53. PMID 15810082 DOI: 10.3748/Wjg.V11.I14.2148  0.438
2005 Chan AW, Chan MW, Lee TL, Ng EK, Leung WK, Lau JY, Tong JH, Chan FK, To KF. Promoter hypermethylation of Death-associated protein-kinase gene associated with advance stage gastric cancer. Oncology Reports. 13: 937-41. PMID 15809761 DOI: 10.3892/Or.13.5.937  0.302
2005 Chan VY, Chan MW, Leung WK, Leung PS, Sung JJ, Chan FK. Intestinal trefoil factor promotes invasion in non-tumorigenic Rat-2 fibroblast cell. Regulatory Peptides. 127: 87-94. PMID 15680474 DOI: 10.1016/J.Regpep.2004.10.016  0.404
2004 Chan HL, Leung WK, To KF, Chan PK, Lee N, Wu A, Tam JS, Sung JJ. Retrospective analysis of liver function derangement in severe acute respiratory syndrome. The American Journal of Medicine. 116: 566-7. PMID 15063822 DOI: 10.1016/J.Amjmed.2003.11.024  0.365
2004 Liu ZM, Chen GG, Ng EK, Leung WK, Sung JJ, Chung SC. Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells. Oncogene. 23: 503-13. PMID 14647439 DOI: 10.1038/Sj.Onc.1207173  0.427
2003 Sung JJ, Chan FK, Lau JY, Yung MY, Leung WK, Wu JC, Ng EK, Chung SC. The effect of endoscopic therapy in patients receiving omeprazole for bleeding ulcers with nonbleeding visible vessels or adherent clots: a randomized comparison. Annals of Internal Medicine. 139: 237-43. PMID 12965978 DOI: 10.7326/0003-4819-139-4-200308190-00005  0.472
2003 Hu P, Yu J, Zeng ZR, Leung W, Sung J. Chemoprevention of gastric cancer by cyclooxygenase-2 inhibitor in rats Gastroenterology. 124: A293. DOI: 10.1016/S0016-5085(03)81477-4  0.371
2002 Leung WK, Hung LC, Kwok CK, Leong RW, Ng DK, Sung JJ. Follow up of serial urea breath test results in patients after consumption of antibiotics for non-gastric infections. World Journal of Gastroenterology : Wjg. 8: 703-6. PMID 12174382 DOI: 10.3748/Wjg.V8.I4.703  0.624
2002 Wu JC, Chan FK, Ching JY, Leung WK, Lee YT, Sung JJ. Empirical treatment based on "typical" reflux symptoms is inappropriate in a population with a high prevalence of Helicobacter pylori infection. Gastrointestinal Endoscopy. 55: 461-5. PMID 11923754 DOI: 10.1067/Mge.2002.122617  0.65
2002 Ng EK, Leung W, To K, Wong SK, Lai PB, Lau W, Sung JJ, Chung SS. The role of early endoscopic follow up after simple closure of perforated duodenal ulcer: A prospective study Annals of the College of Surgeons Hong Kong. 6: 71-76. DOI: 10.1046/J.1442-2034.2002.00136.X  0.546
2001 Chan HL, Wu JC, Chan FK, Choi CL, Ching JY, Lee YT, Leung WK, Lau JY, Chung SC, Sung JJ. Is non-Helicobacter pylori, non-NSAID peptic ulcer a common cause of upper GI bleeding? A prospective study of 977 patients. Gastrointestinal Endoscopy. 53: 438-42. PMID 11275883 DOI: 10.1067/Mge.2001.112840  0.647
2001 Wu JC, Chan FK, Ching JY, Leung W, Hui Y, Chan HL, Lee Y, Sung JJ. Heartburn and acid regurgitation are unreliable diagnostic indicators of gastroesophageal reflux disease (GERD) in population with high prevalence of H. pylori infection Gastroenterology. 120: A729. DOI: 10.1016/S0016-5085(08)83631-1  0.48
2001 Chan FK, To K, Wu JC, Leung W, Lee Y, Yung M, Kwok T, Chan CS, Woo J, Hui E, Sydney Chung S, Sung JJ. Does eradication of Helicobacter pylori before non-steroidal anti-inflammatory drug therapy reduce the long-term risk of ulcers? A double-blinded randomized trial Gastroenterology. 120: A143. DOI: 10.1016/S0016-5085(08)80706-8  0.317
1999 Leung WK, Sung JJ, Ling TK, Siu KL, Cheng AF. Use of chopsticks for eating and Helicobacter pylori infection. Digestive Diseases and Sciences. 44: 1173-6. PMID 10389692 DOI: 10.1023/A:1026632408804  0.366
1998 Lin S, Sung J, Yu A, Ching J, Zhou L, Lam C, Wang R, Leung W, Lau J, Ng E, Chao W, Chung S. The association of lifestyle and dietary factors with the development of precancerous lesions in H. pylori-infected subjects in China Gastroenterology. 114: A636. DOI: 10.1016/S0016-5085(98)82599-7  0.327
1998 Sung J, Leung W, Ling T, Yung M, Chan K, Lee Y, Chung S, Cheng A. Prospective randomized comparison of 1-week RBC-triple therapy versus 1-week PPI-triple therapy for H. pylori-related duodenal ulcers Gastroenterology. 114: A296-A297. DOI: 10.1016/S0016-5085(98)81206-7  0.324
1998 Sung J, Lin S, Ching J, Zhou L, To K, Wang R, Leung W, Wang L, Ng E, Lee Y, Lau J, Chung S, Chao W. Effects of curing Helicobacter pylori infection on precancerous gastric lesions: One-year follow-up of a prospective randomized study in China Gastroenterology. 114: A296. DOI: 10.1016/S0016-5085(98)81205-5  0.375
1998 Ng E, Leung W, Lin S, Sung J, Ching J, To K, Zhou L, Wang R, Chao W, Chung S. The association between anti-CagA serological response and precancerous lesions in Helicobacter pylori-carrying subjects in China Gastroenterology. 114: A242. DOI: 10.1016/S0016-5085(98)80985-2  0.312
1998 Ng E, Leung W, Sung J, Ling T, Lai P, WY L, Chung S. Anti-CagA serology and ulcer recurrence in patients with duodenal ulcer perforation associated with Helicobacter pylori Gastroenterology. 114: A242. DOI: 10.1016/S0016-5085(98)80984-0  0.413
1998 Leung W, Sung J, Siu K, Ling T, Cheng A. Transmission of H. pylori by chopsticks Gastroenterology. 114: A202. DOI: 10.1016/S0016-5085(98)80821-4  0.329
1998 Leung W, Ng E, Sung J. Performance of commercially available serological ELISA test for H. pylori infection: Discrepancy between East and West Gastroenterology. 114: A201. DOI: 10.1016/S0016-5085(98)80820-2  0.336
1998 Chan F, Sung J, Suen R, Lee Y, Leung W, Leung V, Wu J, Chung S. Eradication of H. Pylori versus maintenance acid suppression to prevent recurrent ulcer hemorrhage in high risk NSAID users: A prospective randomizd study Gastroenterology. 114: A87. DOI: 10.1016/S0016-5085(98)80353-3  0.338
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