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Daniel M. Rotroff, Ph.D. - Publications

Affiliations: 
2013 Environmental Sciences & Engineering University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Endocrinology Biology, Toxicology, Bioinformatics Biology
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ash JR, Kuenemann MA, Rotroff D, Motsinger-Reif A, Fourches D. Cheminformatics approach to exploring and modeling trait-associated metabolite profiles. Journal of Cheminformatics. 11: 43. PMID 31236709 DOI: 10.1186/S13321-019-0366-3  0.354
2016 Judson R, Houck K, Martin M, Richard AM, Knudsen TB, Shah I, Little S, Wambaugh J, Setzer RW, Kothiya P, Phuong J, Filer D, Smith D, Reif D, Rotroff D, et al. Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27605417 DOI: 10.1093/Toxsci/Kfw148  0.534
2016 Rotroff DM, Oki NO, Liang X, Yee SW, Stocker SL, Corum DG, Meisner M, Fiehn O, Motsinger-Reif AA, Giacomini KM, Kaddurah-Daouk R. Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans. Frontiers in Pharmacology. 7: 135. PMID 27378919 DOI: 10.3389/Fphar.2016.00135  0.307
2016 Judson R, Houck K, Martin M, Richard AM, Knudsen TB, Shah I, Little S, Wambaugh J, Setzer RW, Kothya P, Phuong J, Filer D, Smith D, Reif D, Rotroff D, et al. Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27208079 DOI: 10.1093/Toxsci/Kfw092  0.584
2015 Judson RS, Magpantay FM, Chickarmane V, Haskell C, Tania N, Taylor J, Xia M, Huang R, Rotroff DM, Filer DL, Houck KA, Martin MT, Sipes N, Richard AM, Mansouri K, et al. Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High Throughput Screening Assays for the Estrogen Receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26272952 DOI: 10.1093/Toxsci/Kfv168  0.6
2015 Motsinger-Reif AA, Rotroff DM. Leveraging Lymphoblastoid Cell Lines for Drug Response Modeling Journal of Data Mining in Genomics & Proteomics. 6. DOI: 10.4172/2153-0602.1000179  0.326
2015 Rotroff D, Breen M, Motsinger-Reif A. Abstract LB-177: Novel approaches for improving interpretation and predictive models of comparative genomic hybridization data Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-177  0.309
2014 Jack J, Rotroff D, Motsinger-Reif A. Lymphoblastoid cell lines models of drug response: successes and lessons from this pharmacogenomic model. Current Molecular Medicine. 14: 833-40. PMID 25109794 DOI: 10.2174/1566524014666140811113946  0.35
2014 Huang R, Sakamuru S, Martin MT, Reif DM, Judson RS, Houck KA, Casey W, Hsieh JH, Shockley KR, Ceger P, Fostel J, Witt KL, Tong W, Rotroff DM, Zhao T, et al. Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway. Scientific Reports. 4: 5664. PMID 25012808 DOI: 10.1038/Srep05664  0.583
2014 Rotroff DM, Martin MT, Dix DJ, Filer DL, Houck KA, Knudsen TB, Sipes NS, Reif DM, Xia M, Huang R, Judson RS. Predictive endocrine testing in the 21st century using in vitro assays of estrogen receptor signaling responses. Environmental Science & Technology. 48: 8706-16. PMID 24960280 DOI: 10.1021/Es502676E  0.597
2014 Paul KB, Hedge JM, Rotroff DM, Hornung MW, Crofton KM, Simmons SO. Development of a thyroperoxidase inhibition assay for high-throughput screening. Chemical Research in Toxicology. 27: 387-99. PMID 24383450 DOI: 10.1021/Tx400310W  0.372
2013 Zang Q, Rotroff DM, Judson RS. Binary classification of a large collection of environmental chemicals from estrogen receptor assays by quantitative structure-activity relationship and machine learning methods. Journal of Chemical Information and Modeling. 53: 3244-61. PMID 24279462 DOI: 10.1021/Ci400527B  0.412
2013 Rotroff DM, Dix DJ, Houck KA, Kavlock RJ, Knudsen TB, Martin MT, Reif DM, Richard AM, Sipes NS, Abassi YA, Jin C, Stampfl M, Judson RS. Real-time growth kinetics measuring hormone mimicry for ToxCast chemicals in T-47D human ductal carcinoma cells. Chemical Research in Toxicology. 26: 1097-107. PMID 23682706 DOI: 10.1021/Tx400117Y  0.57
2013 Rotroff DM, Dix DJ, Houck KA, Knudsen TB, Martin MT, McLaurin KW, Reif DM, Crofton KM, Singh AV, Xia M, Huang R, Judson RS. Using in vitro high throughput screening assays to identify potential endocrine-disrupting chemicals. Environmental Health Perspectives. 121: 7-14. PMID 23052129 DOI: 10.1289/Ehp.1205065  0.577
2012 Kavlock R, Chandler K, Houck K, Hunter S, Judson R, Kleinstreuer N, Knudsen T, Martin M, Padilla S, Reif D, Richard A, Rotroff D, Sipes N, Dix D. Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management. Chemical Research in Toxicology. 25: 1287-302. PMID 22519603 DOI: 10.1021/Tx3000939  0.555
2012 Wetmore BA, Wambaugh JF, Ferguson SS, Sochaski MA, Rotroff DM, Freeman K, Clewell HJ, Dix DJ, Andersen ME, Houck KA, Allen B, Judson RS, Singh R, Kavlock RJ, Richard AM, et al. Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment. Toxicological Sciences : An Official Journal of the Society of Toxicology. 125: 157-74. PMID 21948869 DOI: 10.1093/Toxsci/Kfr254  0.396
2012 Wambaugh BAW, Wambaugh JF, Ferguson SS, Sochaski MA, Rotroff DM, Freeman K, Clewell HJ, Dix DJ, Andersen ME, Houck KA, Allen B, Judson RS, Singh R, Kavlock RJ, Richard AM, et al. Response to "accurate risk-based chemical screening relies on robust exposure estimates" Toxicological Sciences. 128: 297-299. DOI: 10.1093/Toxsci/Kfs144  0.33
2011 Rotroff DM, Dix D, Knudsen T, Martin M, Singh AV, McLaurin K, Reif D, Judson R. Using ToxCast Data to Characterize Assay Utility for More Efficient Endocrine Disruptor Screening. Biology of Reproduction. 85: 797-797. DOI: 10.1093/Biolreprod/85.S1.797  0.535
2011 Martin MT, Rotroff D, Dix DJ. Validation, Acceptance, and Extension of a Predictive Model of Rodent Reproductive Toxicity Using Toxcast High-Throughput Screening. Biology of Reproduction. 85: 791-791. DOI: 10.1093/Biolreprod/85.S1.791  0.543
2010 Rotroff DM, Wetmore BA, Dix DJ, Ferguson SS, Clewell HJ, Houck KA, Lecluyse EL, Andersen ME, Judson RS, Smith CM, Sochaski MA, Kavlock RJ, Boellmann F, Martin MT, Reif DM, et al. Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 348-58. PMID 20639261 DOI: 10.1093/Toxsci/Kfq220  0.578
2010 Judson RS, Martin MT, Reif DM, Houck KA, Knudsen TB, Rotroff DM, Xia M, Sakamuru S, Huang R, Shinn P, Austin CP, Kavlock RJ, Dix DJ. Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity. Environmental Science & Technology. 44: 5979-85. PMID 20602530 DOI: 10.1021/Es102150Z  0.55
2010 Rotroff DM, Beam AL, Dix DJ, Farmer A, Freeman KM, Houck KA, Judson RS, LeCluyse EL, Martin MT, Reif DM, Ferguson SS. Xenobiotic-metabolizing enzyme and transporter gene expression in primary cultures of human hepatocytes modulated by ToxCast chemicals. Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 13: 329-46. PMID 20574906 DOI: 10.1080/10937404.2010.483949  0.539
2010 Judson RS, Houck KA, Kavlock RJ, Knudsen TB, Martin MT, Mortensen HM, Reif DM, Rotroff DM, Shah I, Richard AM, Dix DJ. In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project. Environmental Health Perspectives. 118: 485-92. PMID 20368123 DOI: 10.1289/Ehp.0901392  0.587
2010 Martin MT, Dix DJ, Judson RS, Kavlock RJ, Reif DM, Richard AM, Rotroff DM, Romanov S, Medvedev A, Poltoratskaya N, Gambarian M, Moeser M, Makarov SS, Houck KA. Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program. Chemical Research in Toxicology. 23: 578-90. PMID 20143881 DOI: 10.1021/Tx900325G  0.581
2009 Martin MT, Mendez E, Corum DG, Judson RS, Kavlock RJ, Rotroff DM, Dix DJ. Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database. Toxicological Sciences : An Official Journal of the Society of Toxicology. 110: 181-90. PMID 19363143 DOI: 10.1093/Toxsci/Kfp080  0.561
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