| Year |
Citation |
Score |
| 2018 |
Plochberger B, Axmann M, Röhrl C, Weghuber J, Brameshuber M, Rossboth BK, Mayr S, Ros R, Bittman R, Stangl H, Schütz GJ. Direct observation of cargo transfer from HDL particles to the plasma membrane. Atherosclerosis. 277: 53-59. PMID 30173079 DOI: 10.1016/J.Atherosclerosis.2018.08.032 |
0.318 |
|
| 2018 |
Kinnun JJ, Bittman R, Shaikh SR, Wassall SR. DHA Modifies the Size and Composition of Raftlike Domains: A Solid-State 2H NMR Study. Biophysical Journal. 114: 380-391. PMID 29401435 DOI: 10.1016/J.Bpj.2017.11.023 |
0.314 |
|
| 2017 |
Plochberger B, Röhrl C, Preiner J, Rankl C, Brameshuber M, Madl J, Bittman R, Ros R, Sezgin E, Eggeling C, Hinterdorfer P, Stangl H, Schütz GJ. HDL particles incorporate into lipid bilayers - a combined AFM and single molecule fluorescence microscopy study. Scientific Reports. 7: 15886. PMID 29162870 DOI: 10.1038/S41598-017-15949-7 |
0.331 |
|
| 2016 |
Vogel A, Scheidt HA, Baek DJ, Bittman R, Huster D. Structure and dynamics of the aliphatic cholesterol side chain in membranes as studied by (2)H NMR spectroscopy and molecular dynamics simulation. Physical Chemistry Chemical Physics : Pccp. 18: 3730-8. PMID 26762541 DOI: 10.1039/C5Cp05084G |
0.349 |
|
| 2016 |
Huster D, Meyer T, Nikolaus J, Jae Baek D, Haralampiev I, Bittman R, Müller P, Herrmann A, Scheidt HA. Cholesterol's Aliphatic Side Chain Structure Modulates Membrane Properties Biophysical Journal. 110: 84a. DOI: 10.1016/J.Bpj.2015.11.510 |
0.352 |
|
| 2016 |
Kinnun JJ, Williams JA, Stillwell W, Bittman R, Shaikh SR, Wassall SR. Solid-state 2H NMR Reveals the Impact of DHA on Molecular Organization in Raft-Like Domains Biophysical Journal. 110: 82a. DOI: 10.1016/J.Bpj.2015.11.504 |
0.348 |
|
| 2015 |
Perera MN, Ganesan V, Siskind LJ, Szulc ZM, Bielawska A, Bittman R, Colombini M. Ceramide channel: Structural basis for selective membrane targeting. Chemistry and Physics of Lipids. PMID 26408265 DOI: 10.1016/J.Chemphyslip.2015.09.007 |
0.337 |
|
| 2015 |
Blom T, Li S, Dichlberger A, Bäck N, Kim YA, Loizides-Mangold U, Riezman H, Bittman R, Ikonen E. LAPTM4B facilitates late endosomal ceramide export to control cell death pathways. Nature Chemical Biology. 11: 799-806. PMID 26280656 DOI: 10.1038/Nchembio.1889 |
0.308 |
|
| 2015 |
Camp SM, Chiang ET, Sun C, Usatyuk PV, Bittman R, Natarajan V, Garcia JG, Dudek SM. Pulmonary Endothelial Cell Barrier Enhancement by Novel FTY720 Analogs: Methoxy-FTY720, Fluoro-FTY720, and β-Glucuronide-FTY720. Chemistry and Physics of Lipids. 191: 16-24. PMID 26272033 DOI: 10.1016/J.Chemphyslip.2015.08.004 |
0.309 |
|
| 2015 |
Vilchèze C, Leung LW, Bittman R, Jacobs WR. Synthesis and biological activity of alkynoic acids derivatives against mycobacteria. Chemistry and Physics of Lipids. PMID 26256431 DOI: 10.1016/J.Chemphyslip.2015.08.001 |
0.305 |
|
| 2015 |
Mahendran A, Ghogare AA, Bittman R, Arthur G, Greer A. Synthesis and antiproliferative properties of a new ceramide analog of varacin. Chemistry and Physics of Lipids. PMID 26254858 DOI: 10.1016/J.Chemphyslip.2015.07.023 |
0.304 |
|
| 2015 |
Kim YA, Day J, Lirette CA, Costain WJ, Johnston LJ, Bittman R. Synthesis and photochemical properties of PEGylated coumarin-caged ceramides for cell studies. Chemistry and Physics of Lipids. PMID 26200920 DOI: 10.1016/J.Chemphyslip.2015.07.006 |
0.34 |
|
| 2015 |
Hawkes D, Jones KL, Smyth RP, Pereira CF, Bittman R, Jaworowski A, Mak J. Properties of HIV-1 associated cholesterol in addition to raft formation are important for virus infection. Virus Research. 210: 18-21. PMID 26191619 DOI: 10.1016/J.Virusres.2015.06.023 |
0.306 |
|
| 2015 |
Boomkamp SD, Byun HS, Ubhi S, Jiang HR, Pyne S, Bittman R, Pyne NJ. Effect of ether glycerol lipids on interleukin-1β release and experimental autoimmune encephalomyelitis. Chemistry and Physics of Lipids. PMID 26187854 DOI: 10.1016/J.Chemphyslip.2015.07.001 |
0.309 |
|
| 2015 |
Kinnun JJ, Williams JA, Stillwell W, Bittman R, Shaikh SR, Wassall SR. DHA Disorders Raft-Like Domains as Revealed by Solid State 2H NMR Biophysical Journal. 108: 412a. DOI: 10.1016/J.Bpj.2014.11.2258 |
0.338 |
|
| 2014 |
Ouro A, Arana L, Rivera IG, Ordoñez M, Gomez-Larrauri A, Presa N, Simón J, Trueba M, Gangoiti P, Bittman R, Gomez-Muñoz A. Phosphatidic acid inhibits ceramide 1-phosphate-stimulated macrophage migration. Biochemical Pharmacology. 92: 642-50. PMID 25450673 DOI: 10.1016/J.Bcp.2014.10.005 |
0.328 |
|
| 2014 |
Venkataswamy MM, Ng TW, Kharkwal SS, Carreño LJ, Johnson AJ, Kunnath-Velayudhan S, Liu Z, Bittman R, Jervis PJ, Cox LR, Besra GS, Wen X, Yuan W, Tsuji M, Li X, et al. Improving Mycobacterium bovis bacillus Calmette-Guèrin as a vaccine delivery vector for viral antigens by incorporation of glycolipid activators of NKT cells. Plos One. 9: e108383. PMID 25255287 DOI: 10.1371/Journal.Pone.0108383 |
0.344 |
|
| 2014 |
Evangelisti C, Evangelisti C, Teti G, Chiarini F, Falconi M, Melchionda F, Pession A, Bertaina A, Locatelli F, McCubrey JA, Beak DJ, Bittman R, Pyne S, Pyne NJ, Martelli AM. Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics. Oncotarget. 5: 7886-901. PMID 25226616 DOI: 10.18632/Oncotarget.2318 |
0.3 |
|
| 2014 |
Meyer T, Baek DJ, Bittman R, Haralampiev I, Müller P, Herrmann A, Huster D, Scheidt HA. Membrane properties of cholesterol analogs with an unbranched aliphatic side chain. Chemistry and Physics of Lipids. 184: 1-6. PMID 25173446 DOI: 10.1016/J.Chemphyslip.2014.08.002 |
0.364 |
|
| 2014 |
Neuvonen M, Manna M, Mokkila S, Javanainen M, Rog T, Liu Z, Bittman R, Vattulainen I, Ikonen E. Enzymatic oxidation of cholesterol: properties and functional effects of cholestenone in cell membranes. Plos One. 9: e103743. PMID 25157633 DOI: 10.1371/Journal.Pone.0103743 |
0.44 |
|
| 2014 |
Liu Z, Thacker SG, Fernandez-Castillejo S, Neufeld EB, Remaley AT, Bittman R. Synthesis of cholesterol analogues bearing BODIPY fluorophores by Suzuki or Liebeskind-Srogl cross-coupling and evaluation of their potential for visualization of cholesterol pools. Chembiochem : a European Journal of Chemical Biology. 15: 2087-96. PMID 25154602 DOI: 10.1002/Cbic.201402042 |
0.437 |
|
| 2014 |
Fruhwürth S, Kovacs WJ, Bittman R, Messner S, Röhrl C, Stangl H. Differential basolateral-apical distribution of scavenger receptor, class B, type I in cultured cells and the liver. Histochemistry and Cell Biology. 142: 645-55. PMID 25059650 DOI: 10.1007/S00418-014-1251-9 |
0.329 |
|
| 2014 |
Fruhwürth S, Krieger S, Winter K, Rosner M, Mikula M, Weichhart T, Bittman R, Hengstschläger M, Stangl H. Inhibition of mTOR down-regulates scavenger receptor, class B, type I (SR-BI) expression, reduces endothelial cell migration and impairs nitric oxide production. Biochimica Et Biophysica Acta. 1841: 944-53. PMID 24713582 DOI: 10.1016/J.Bbalip.2014.03.014 |
0.334 |
|
| 2014 |
Arora P, Baena A, Yu KO, Saini NK, Kharkwal SS, Goldberg MF, Kunnath-Velayudhan S, Carreño LJ, Venkataswamy MM, Kim J, Lazar-Molnar E, Lauvau G, Chang YT, Liu Z, Bittman R, et al. A single subset of dendritic cells controls the cytokine bias of natural killer T cell responses to diverse glycolipid antigens. Immunity. 40: 105-16. PMID 24412610 DOI: 10.1016/J.Immuni.2013.12.004 |
0.347 |
|
| 2014 |
Kinnun JJ, Williams JA, Stillwell W, Bittman R, Raza Shaikh S, Wassall SR. Solid State 2H NMR Studies of the Disordering of Raft-Like Domains by n-3 PUFA Biophysical Journal. 106: 94a. DOI: 10.1016/J.Bpj.2013.11.590 |
0.356 |
|
| 2014 |
Plochberger B, Schuetz GJ, Röhrl C, Preiner J, Sezgin E, Brameshuber M, Weghuber J, Wieser S, Rankl C, Ruprecht V, Madl J, Bittman R, Hinterdorfer P, Stangl H. HDL-Lipid Uptake is Regulated by Elastic Properties of the Plasma Membrane Biophysical Journal. 106: 392a. DOI: 10.1016/J.Bpj.2013.11.2216 |
0.341 |
|
| 2013 |
Scheidt HA, Meyer T, Nikolaus J, Baek DJ, Haralampiev I, Thomas L, Bittman R, Müller P, Herrmann A, Huster D. Cholesterol's aliphatic side chain modulates membrane properties. Angewandte Chemie (International Ed. in English). 52: 12848-51. PMID 24382636 DOI: 10.1002/Anie.201306753 |
0.34 |
|
| 2013 |
Fruhwürth S, Pavelka M, Bittman R, Kovacs WJ, Walter KM, Röhrl C, Stangl H. High-density lipoprotein endocytosis in endothelial cells. World Journal of Biological Chemistry. 4: 131-40. PMID 24340136 DOI: 10.4331/Wjbc.V4.I4.131 |
0.322 |
|
| 2013 |
Solanko LM, Honigmann A, Midtiby HS, Lund FW, Brewer JR, Dekaris V, Bittman R, Eggeling C, Wüstner D. Membrane orientation and lateral diffusion of BODIPY-cholesterol as a function of probe structure. Biophysical Journal. 105: 2082-92. PMID 24209853 DOI: 10.1016/J.Bpj.2013.09.031 |
0.314 |
|
| 2013 |
Kanerva K, Uronen RL, Blom T, Li S, Bittman R, Lappalainen P, Peränen J, Raposo G, Ikonen E. LDL cholesterol recycles to the plasma membrane via a Rab8a-Myosin5b-actin-dependent membrane transport route. Developmental Cell. 27: 249-62. PMID 24209575 DOI: 10.1016/J.Devcel.2013.09.016 |
0.363 |
|
| 2013 |
Baek DJ, MacRitchie N, Anthony NG, Mackay SP, Pyne S, Pyne NJ, Bittman R. Structure-activity relationships and molecular modeling of sphingosine kinase inhibitors. Journal of Medicinal Chemistry. 56: 9310-27. PMID 24164513 DOI: 10.1021/Jm401399C |
0.328 |
|
| 2013 |
GarcÃa-MartÃnez V, Villanueva J, Torregrosa-Hetland CJ, Bittman R, Higdon A, Darley-Usmar VM, Davletov B, Gutiérrez LM. Lipid metabolites enhance secretion acting on SNARE microdomains and altering the extent and kinetics of single release events in bovine adrenal chromaffin cells. Plos One. 8: e75845. PMID 24073281 DOI: 10.1371/Journal.Pone.0075845 |
0.331 |
|
| 2013 |
Baek DJ, Bittman R. Synthesis of cholesterol analogs having varying length alkyl side chains including cholesterol-23, 23, 24, 24, 25, 26, 26, 26, 27, 27, 27-d(11) as probes of cholesterol's functions and properties. Chemistry and Physics of Lipids. 175: 99-104. PMID 24012903 DOI: 10.1016/J.Chemphyslip.2013.08.003 |
0.374 |
|
| 2013 |
Pietiäinen V, Vassilev B, Blom T, Wang W, Nelson J, Bittman R, Bäck N, Zelcer N, Ikonen E. NDRG1 functions in LDL receptor trafficking by regulating endosomal recycling and degradation. Journal of Cell Science. 126: 3961-71. PMID 23813961 DOI: 10.1242/Jcs.128132 |
0.333 |
|
| 2013 |
Fells JI, Lee SC, Fujiwara Y, Norman DD, Lim KG, Tsukahara R, Liu J, Patil R, Miller DD, Kirby RJ, Nelson S, Seibel W, Papoian R, Parrill AL, Baker DL, ... Bittman R, et al. Hits of a high-throughput screen identify the hydrophobic pocket of autotaxin/lysophospholipase D as an inhibitory surface. Molecular Pharmacology. 84: 415-24. PMID 23793291 DOI: 10.1124/Mol.113.087080 |
0.319 |
|
| 2013 |
Carter Ramirez DM, Kim YA, Bittman R, Johnston LJ. Lipid Phase Separation and Protein-Ganglioside Clustering in Supported Bilayers Are Induced by Photorelease of Ceramide. Soft Matter. 9: 4890-4899. PMID 23667384 DOI: 10.1039/C3Sm50240F |
0.331 |
|
| 2013 |
Milles S, Meyer T, Scheidt HA, Schwarzer R, Thomas L, Marek M, Szente L, Bittman R, Herrmann A, Günther Pomorski T, Huster D, Müller P. Organization of fluorescent cholesterol analogs in lipid bilayers - lessons from cyclodextrin extraction. Biochimica Et Biophysica Acta. 1828: 1822-8. PMID 23583923 DOI: 10.1016/J.Bbamem.2013.04.002 |
0.338 |
|
| 2013 |
Liu Z, MacRitchie N, Pyne S, Pyne NJ, Bittman R. Synthesis of (S)-FTY720 vinylphosphonate analogues and evaluation of their potential as sphingosine kinase 1 inhibitors and activators. Bioorganic & Medicinal Chemistry. 21: 2503-10. PMID 23541833 DOI: 10.1016/J.Bmc.2013.02.042 |
0.413 |
|
| 2013 |
Martel C, Li W, Fulp B, Platt AM, Gautier EL, Westerterp M, Bittman R, Tall AR, Chen SH, Thomas MJ, Kreisel D, Swartz MA, Sorci-Thomas MG, Randolph GJ. Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice. The Journal of Clinical Investigation. 123: 1571-9. PMID 23524964 DOI: 10.1172/Jci63685 |
0.301 |
|
| 2013 |
Ramirez DM, Pitre SP, Kim YA, Bittman R, Johnston LJ. Photouncaging of ceramides promotes reorganization of liquid-ordered domains in supported lipid bilayers. Langmuir : the Acs Journal of Surfaces and Colloids. 29: 3380-7. PMID 23402522 DOI: 10.1021/La3039158 |
0.309 |
|
| 2013 |
Ouro A, Arana L, Gangoiti P, Rivera IG, Ordoñez M, Trueba M, Lankalapalli RS, Bittman R, Gomez-Muñoz A. Ceramide 1-phosphate stimulates glucose uptake in macrophages. Cellular Signalling. 25: 786-95. PMID 23333242 DOI: 10.1016/J.Cellsig.2013.01.009 |
0.627 |
|
| 2013 |
Watson DG, Tonelli F, Alossaimi M, Williamson L, Chan E, Gorshkova I, Berdyshev E, Bittman R, Pyne NJ, Pyne S. The roles of sphingosine kinases 1 and 2 in regulating the Warburg effect in prostate cancer cells Cellular Signalling. 25: 1011-1017. PMID 23314175 DOI: 10.1016/J.Cellsig.2013.01.002 |
0.341 |
|
| 2013 |
Baek DJ, Park JS, Lee JY, Lim C, Kang CY, Bittman R. Synthesis and bioactivity of α-galactosylceramide analogues bearing an aryl group within the fatty amide chain Tetrahedron Letters. 54: 6660-6664. DOI: 10.1016/J.Tetlet.2013.09.134 |
0.322 |
|
| 2013 |
Kinnun JJ, Williams JA, Bittman R, Shaikh SR, Wassall SR. Disordering of Raft Domains by DHA and EPA observed with Solid-State Deuterium NMR Spectroscopy Biophysical Journal. 104: 588a. DOI: 10.1016/J.Bpj.2012.11.3271 |
0.35 |
|
| 2012 |
Lund FW, Lomholt MA, Solanko LM, Bittman R, Wüstner D. Two-photon time-lapse microscopy of BODIPY-cholesterol reveals anomalous sterol diffusion in chinese hamster ovary cells. Bmc Biophysics. 5: 20. PMID 23078907 DOI: 10.1186/2046-1682-5-20 |
0.31 |
|
| 2012 |
Liu Z, Courtney AN, Metelitsa LS, Bittman R. C-Glycosphingolipids with an exo-methylene substituent: stereocontrolled synthesis and immunostimulation of mouse and human natural killer T lymphocytes. Chembiochem : a European Journal of Chemical Biology. 13: 1733-7. PMID 22782839 DOI: 10.1002/Cbic.201200374 |
0.402 |
|
| 2012 |
Walters JW, Anderson JL, Bittman R, Pack M, Farber SA. Visualization of lipid metabolism in the zebrafish intestine reveals a relationship between NPC1L1-mediated cholesterol uptake and dietary fatty acid. Chemistry & Biology. 19: 913-25. PMID 22749558 DOI: 10.1016/J.Chembiol.2012.05.018 |
0.32 |
|
| 2012 |
Upadhyaya P, Kumar A, Byun HS, Bittman R, Saba JD, Hecht SS. The sphingolipid degradation product trans-2-hexadecenal forms adducts with DNA. Biochemical and Biophysical Research Communications. 424: 18-21. PMID 22727907 DOI: 10.1016/J.Bbrc.2012.06.012 |
0.31 |
|
| 2012 |
Lim KG, Tonelli F, Berdyshev E, Gorshkova I, Leclercq T, Pitson SM, Bittman R, Pyne S, Pyne NJ. Inhibition kinetics and regulation of sphingosine kinase 1 expression in prostate cancer cells: functional differences between sphingosine kinase 1a and 1b. The International Journal of Biochemistry & Cell Biology. 44: 1457-64. PMID 22634604 DOI: 10.1016/J.Biocel.2012.05.012 |
0.312 |
|
| 2012 |
Blom T, Li Z, Bittman R, Somerharju P, Ikonen E. Tracking sphingosine metabolism and transport in sphingolipidoses: NPC1 deficiency as a test case. Traffic (Copenhagen, Denmark). 13: 1234-43. PMID 22607065 DOI: 10.1111/J.1600-0854.2012.01379.X |
0.313 |
|
| 2012 |
Liu Z, Bittman R. Synthesis of C-glycoside analogues of α-galactosylceramide via linear allylic C-H oxidation and allyl cyanate to isocyanate rearrangement. Organic Letters. 14: 620-3. PMID 22233351 DOI: 10.1021/Ol2032448 |
0.393 |
|
| 2012 |
Arana L, Gangoiti P, Ouro A, Rivera IG, Ordoñez M, Trueba M, Lankalapalli RS, Bittman R, Gomez-Muñoz A. Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate. Experimental Cell Research. 318: 350-60. PMID 22155727 DOI: 10.1016/J.Yexcr.2011.11.013 |
0.642 |
|
| 2012 |
Röhrl C, Meisslitzer-Ruppitsch C, Bittman R, Li Z, Pabst G, Prassl R, Strobl W, Neumüller J, Ellinger A, Pavelka M, Stangl H. Combined light and electron microscopy using diaminobenzidine photooxidation to monitor trafficking of lipids derived from lipoprotein particles. Current Pharmaceutical Biotechnology. 13: 331-40. PMID 21470121 DOI: 10.2174/138920112799095338 |
0.325 |
|
| 2012 |
Ramirez DMC, Ah Kim Y, Costain W, Bittman R, Johnston LJ. Probing the Structural and Signalling Roles of Ceramide using 6-Bromo-7-Hydroxycoumarin Caged Derivatives Biophysical Journal. 102: 303a-304a. DOI: 10.1016/J.Bpj.2011.11.1677 |
0.366 |
|
| 2011 |
Patel O, Cameron G, Pellicci DG, Liu Z, Byun HS, Beddoe T, McCluskey J, Franck RW, Castaño AR, Harrak Y, Llebaria A, Bittman R, Porcelli SA, Godfrey DI, Rossjohn J. NKT TCR recognition of CD1d-α-C-galactosylceramide. Journal of Immunology (Baltimore, Md. : 1950). 187: 4705-13. PMID 21964029 DOI: 10.4049/Jimmunol.1100794 |
0.588 |
|
| 2011 |
Liu Z, Byun HS, Bittman R. Total synthesis of α-1C-galactosylceramide, an immunostimulatory C-glycosphingolipid, and confirmation of the stereochemistry in the first-generation synthesis. The Journal of Organic Chemistry. 76: 8588-98. PMID 21958232 DOI: 10.1021/Jo201450S |
0.438 |
|
| 2011 |
Sankaranarayanan S, Kellner-Weibel G, de la Llera-Moya M, Phillips MC, Asztalos BF, Bittman R, Rothblat GH. A sensitive assay for ABCA1-mediated cholesterol efflux using BODIPY-cholesterol. Journal of Lipid Research. 52: 2332-40. PMID 21957199 DOI: 10.1194/Jlr.D018051 |
0.32 |
|
| 2011 |
Bidet M, Joubert O, Lacombe B, Ciantar M, Nehmé R, Mollat P, Brétillon L, Faure H, Bittman R, Ruat M, Mus-Veteau I. The hedgehog receptor patched is involved in cholesterol transport. Plos One. 6: e23834. PMID 21931618 DOI: 10.1371/Journal.Pone.0023834 |
0.351 |
|
| 2011 |
Kim YA, Ramirez DM, Costain WJ, Johnston LJ, Bittman R. A new tool to assess ceramide bioactivity: 6-bromo-7-hydroxycoumarinyl-caged ceramide. Chemical Communications (Cambridge, England). 47: 9236-8. PMID 21761060 DOI: 10.1039/C1Cc12345A |
0.307 |
|
| 2011 |
Lim KG, Sun C, Bittman R, Pyne NJ, Pyne S. (R)-FTY720 methyl ether is a specific sphingosine kinase 2 inhibitor: Effect on sphingosine kinase 2 expression in HEK 293 cells and actin rearrangement and survival of MCF-7 breast cancer cells. Cellular Signalling. 23: 1590-5. PMID 21620961 DOI: 10.1016/J.Cellsig.2011.05.010 |
0.326 |
|
| 2011 |
Lim KG, Tonelli F, Li Z, Lu X, Bittman R, Pyne S, Pyne NJ. FTY720 analogues as sphingosine kinase 1 inhibitors: enzyme inhibition kinetics, allosterism, proteasomal degradation, and actin rearrangement in MCF-7 breast cancer cells. The Journal of Biological Chemistry. 286: 18633-40. PMID 21464128 DOI: 10.1074/Jbc.M111.220756 |
0.553 |
|
| 2011 |
Kumar A, Byun HS, Bittman R, Saba JD. The sphingolipid degradation product trans-2-hexadecenal induces cytoskeletal reorganization and apoptosis in a JNK-dependent manner. Cellular Signalling. 23: 1144-52. PMID 21385609 DOI: 10.1016/J.Cellsig.2011.02.009 |
0.341 |
|
| 2011 |
Wüstner D, Solanko L, Sokol E, Garvik O, Li Z, Bittman R, Korte T, Herrmann A. Quantitative assessment of sterol traffic in living cells by dual labeling with dehydroergosterol and BODIPY-cholesterol. Chemistry and Physics of Lipids. 164: 221-35. PMID 21291873 DOI: 10.1016/J.Chemphyslip.2011.01.004 |
0.362 |
|
| 2011 |
Berdyshev EV, Goya J, Gorshkova I, Prestwich GD, Byun HS, Bittman R, Natarajan V. Characterization of sphingosine-1-phosphate lyase activity by electrospray ionization-liquid chromatography/tandem mass spectrometry quantitation of (2E)-hexadecenal. Analytical Biochemistry. 408: 12-8. PMID 20804717 DOI: 10.1016/J.Ab.2010.08.026 |
0.318 |
|
| 2011 |
Oaks JJ, Mukhopadhyay A, Santhanam R, Saddoughi SA, Neviani P, Harb JG, Ogretmen B, Bittman R, Levine RL, Quintás-Cardama A, Marcucci G, Perrotti D. FTY720 Restores PP2A Tumor Suppressor Activity in Polycythemia Vera CD34+ Progenitors Through Inhibition of Jak2 V617F- and PI-3Kγ-Dependent SET Serine Phosphorylation and Enhancement of NOS-Dependent PP2A Tyrosine Nitration Blood. 118: 2494-2494. DOI: 10.1182/Blood.V118.21.2494.2494 |
0.305 |
|
| 2010 |
Scolari S, Müller K, Bittman R, Herrmann A, Müller P. Interaction of mammalian seminal plasma protein PDC-109 with cholesterol: implications for a putative CRAC domain. Biochemistry. 49: 9027-31. PMID 20863067 DOI: 10.1021/Bi101257C |
0.341 |
|
| 2010 |
Byun HS, Bittman R. Selective deuterium labeling of the sphingoid backbone: facile syntheses of 3,4,5-trideuterio-d-erythro-sphingosine and 3-deuterio-d-erythro-sphingomyelin. Chemistry and Physics of Lipids. 163: 809-13. PMID 20836998 DOI: 10.1016/J.Chemphyslip.2010.09.001 |
0.31 |
|
| 2010 |
Bucki R, Ku?akowska A, Byfield FJ, Zendzian-Piotrowska M, Baranowski M, Marzec M, Winer JP, Ciccarelli NJ, Górski J, Drozdowski W, Bittman R, Janmey PA. Plasma gelsolin modulates cellular response to sphingosine 1-phosphate American Journal of Physiology - Cell Physiology. 299: C1516-C1523. PMID 20810916 DOI: 10.1152/Ajpcell.00051.2010 |
0.313 |
|
| 2010 |
Mahendran A, Vuong A, Aebisher D, Gong Y, Bittman R, Arthur G, Kawamura A, Greer A. Synthesis, characterization, mechanism of decomposition, and antiproliferative activity of a class of PEGylated benzopolysulfanes structurally similar to the natural product varacin. The Journal of Organic Chemistry. 75: 5549-57. PMID 20704430 DOI: 10.1021/Jo100870Q |
0.329 |
|
| 2010 |
Tonelli F, Lim KG, Loveridge C, Long J, Pitson SM, Tigyi G, Bittman R, Pyne S, Pyne NJ. FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells. Cellular Signalling. 22: 1536-42. PMID 20570726 DOI: 10.1016/J.Cellsig.2010.05.022 |
0.307 |
|
| 2010 |
Valentine WJ, Kiss GN, Liu J, E S, Gotoh M, Murakami-Murofushi K, Pham TC, Baker DL, Parrill AL, Lu X, Sun C, Bittman R, Pyne NJ, Tigyi G. (S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity. Cellular Signalling. 22: 1543-53. PMID 20566326 DOI: 10.1016/J.Cellsig.2010.05.023 |
0.55 |
|
| 2010 |
Habrukowich C, Han DK, Le A, Rezaul K, Pan W, Ghosh M, Li Z, Dodge-Kafka K, Jiang X, Bittman R, Hla T. Sphingosine interaction with acidic leucine-rich nuclear phosphoprotein-32A (ANP32A) regulates PP2A activity and cyclooxygenase (COX)-2 expression in human endothelial cells. The Journal of Biological Chemistry. 285: 26825-31. PMID 20558741 DOI: 10.1074/Jbc.M110.147058 |
0.311 |
|
| 2010 |
Liu Z, Byun HS, Bittman R. Asymmetric synthesis of D-ribo-phytosphingosine from 1-tetradecyne and (4-methoxyphenoxy)acetaldehyde. The Journal of Organic Chemistry. 75: 4356-64. PMID 20527744 DOI: 10.1021/Jo100707D |
0.399 |
|
| 2010 |
Liu Z, Byun HS, Bittman R. Synthesis of immunostimulatory alpha-C-galactosylceramide glycolipids via Sonogashira coupling, asymmetric epoxidation, and trichloroacetimidate-mediated epoxide opening. Organic Letters. 12: 2974-7. PMID 20518525 DOI: 10.1021/Ol1009976 |
0.39 |
|
| 2010 |
Lankalapalli RS, Baksa A, Liliom K, Bittman R. Synthesis and properties of a photoactivatable analogue of psychosine (beta-Galactosylsphingosine). Chemmedchem. 5: 682-6. PMID 20209561 DOI: 10.1002/Cmdc.201000018 |
0.687 |
|
| 2010 |
Heller B, Adu-Gyamfi E, Smith-Kinnaman W, Babbey C, Vora M, Xue Y, Bittman R, Stahelin RV, Wells CD. Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domain. The Journal of Biological Chemistry. 285: 12308-20. PMID 20080965 DOI: 10.1074/Jbc.M109.096230 |
0.326 |
|
| 2010 |
Blom T, Bäck N, Mutka AL, Bittman R, Li Z, de Lera A, Kovanen PT, Diczfalusy U, Ikonen E. FTY720 stimulates 27-hydroxycholesterol production and confers atheroprotective effects in human primary macrophages. Circulation Research. 106: 720-9. PMID 20056921 DOI: 10.1161/Circresaha.109.204396 |
0.347 |
|
| 2010 |
Oaks JJ, Mukhopadhyay A, Santhanam R, Saddoughi SA, Walker C, Neviani P, Harb JG, Ma Y, Verstovsek S, Marcucci G, Briesewitz R, Bittman R, Chen C, Quintas-Cardama A, Ogretmen B, et al. Pharmacologic Restoration of PP2A Activity and Interference with the SET-PP2A Interplay by FTY720 and Its Non-Immunosuppressive Derivative as a Novel and Efficient Therapy for Ph-Negative Myeloproliferative Disorders Blood. 116: 775-775. DOI: 10.1182/Blood.V116.21.775.775 |
0.322 |
|
| 2010 |
Walker C, Oaks JJ, Neviani P, Harb JG, Santhanam R, Ma Y, Marcucci G, Van Brocklyn J, Chen C, Bittman R, Perrotti D. PP2A Activating Drugs (PAD): Anti-Leukemic and Non-Toxic Activity of Two Novel and Non-Immunosuppressive FTY720 Derivatives Blood. 116: 2901-2901. DOI: 10.1182/Blood.V116.21.2901.2901 |
0.327 |
|
| 2010 |
Liu Z, Gong Y, Byun HS, Bittman R. An improved two-step synthetic route to primary allylic alcohols from aldehydes New Journal of Chemistry. 34: 470-475. DOI: 10.1039/B9Nj00710E |
0.35 |
|
| 2009 |
Lankalapalli RS, Ouro A, Arana L, Gómez-Muñoz A, Bittman R. Caged ceramide 1-phosphate analogues: synthesis and properties. The Journal of Organic Chemistry. 74: 8844-7. PMID 19908915 DOI: 10.1021/Jo902076W |
0.664 |
|
| 2009 |
Camp SM, Bittman R, Chiang ET, Moreno-Vinasco L, Mirzapoiazova T, Sammani S, Lu X, Sun C, Harbeck M, Roe M, Natarajan V, Garcia JG, Dudek SM. Synthetic analogs of FTY720 [2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol] differentially regulate pulmonary vascular permeability in vivo and in vitro. The Journal of Pharmacology and Experimental Therapeutics. 331: 54-64. PMID 19592667 DOI: 10.1124/Jpet.109.153544 |
0.559 |
|
| 2009 |
Lankalapalli RS, Eckelkamp JT, Sircar D, Ford DA, Subbaiah PV, Bittman R. Synthesis and antioxidant properties of an unnatural plasmalogen analogue bearing a trans O-vinyl ether linkage. Organic Letters. 11: 2784-7. PMID 19499908 DOI: 10.1021/Ol9009078 |
0.67 |
|
| 2009 |
Lahiri S, Park H, Laviad EL, Lu X, Bittman R, Futerman AH. Ceramide synthesis is modulated by the sphingosine analog FTY720 via a mixture of uncompetitive and noncompetitive inhibition in an Acyl-CoA chain length-dependent manner. The Journal of Biological Chemistry. 284: 16090-8. PMID 19357080 DOI: 10.1074/Jbc.M807438200 |
0.571 |
|
| 2009 |
Ariola FS, Li Z, Cornejo C, Bittman R, Heikal AA. Membrane fluidity and lipid order in ternary giant unilamellar vesicles using a new bodipy-cholesterol derivative. Biophysical Journal. 96: 2696-708. PMID 19348752 DOI: 10.1016/J.Bpj.2008.12.3922 |
0.355 |
|
| 2009 |
Lu X, Sun C, Valentine WJ, Shuyu E, Liu J, Tigyi G, Bittman R. Chiral vinylphosphonate and phosphonate analogues of the immunosuppressive agent FTY720. The Journal of Organic Chemistry. 74: 3192-5. PMID 19296586 DOI: 10.1021/Jo900023U |
0.562 |
|
| 2009 |
Berdyshev EV, Gorshkova I, Skobeleva A, Bittman R, Lu X, Dudek SM, Mirzapoiazova T, Garcia JG, Natarajan V. FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells. The Journal of Biological Chemistry. 284: 5467-77. PMID 19119142 DOI: 10.1074/Jbc.M805186200 |
0.569 |
|
| 2009 |
Subbaiah PV, Sircar D, Lankalapalli RS, Bittman R. Effect of double bond geometry in sphingosine base on the antioxidant function of sphingomyelin. Archives of Biochemistry and Biophysics. 481: 72-9. PMID 18952047 DOI: 10.1016/J.Abb.2008.10.005 |
0.647 |
|
| 2008 |
Bartels T, Lankalapalli RS, Bittman R, Beyer K, Brown MF. Raftlike mixtures of sphingomyelin and cholesterol investigated by solid-state 2H NMR spectroscopy. Journal of the American Chemical Society. 130: 14521-32. PMID 18839945 DOI: 10.1021/Ja801789T |
0.67 |
|
| 2008 |
Marks DL, Bittman R, Pagano RE. Use of Bodipy-labeled sphingolipid and cholesterol analogs to examine membrane microdomains in cells. Histochemistry and Cell Biology. 130: 819-32. PMID 18820942 DOI: 10.1007/S00418-008-0509-5 |
0.331 |
|
| 2008 |
Hölttä-Vuori M, Uronen RL, Repakova J, Salonen E, Vattulainen I, Panula P, Li Z, Bittman R, Ikonen E. BODIPY-cholesterol: a new tool to visualize sterol trafficking in living cells and organisms. Traffic (Copenhagen, Denmark). 9: 1839-49. PMID 18647169 DOI: 10.1111/J.1600-0854.2008.00801.X |
0.329 |
|
| 2008 |
Chiantia S, Ries J, Chwastek G, Carrer D, Li Z, Bittman R, Schwille P. Role of ceramide in membrane protein organization investigated by combined AFM and FCS. Biochimica Et Biophysica Acta. 1778: 1356-64. PMID 18346453 DOI: 10.1016/J.Bbamem.2008.02.008 |
0.323 |
|
| 2008 |
Soni SP, LoCascio DS, Liu Y, Williams JA, Bittman R, Stillwell W, Wassall SR. Docosahexaenoic acid enhances segregation of lipids between : 2H-NMR study. Biophysical Journal. 95: 203-14. PMID 18339742 DOI: 10.1529/Biophysj.107.123612 |
0.517 |
|
| 2008 |
Fyrst H, Zhang X, Herr DR, Byun HS, Bittman R, Phan VH, Harris GL, Saba JD. Identification and characterization by electrospray mass spectrometry of endogenous Drosophila sphingadienes. Journal of Lipid Research. 49: 597-606. PMID 18156591 DOI: 10.1194/Jlr.M700414-Jlr200 |
0.347 |
|
| 2007 |
Li Z, Bittman R. Synthesis and spectral properties of cholesterol- and FTY720-containing boron dipyrromethene dyes Journal of Organic Chemistry. 72: 8376-8382. PMID 17914846 DOI: 10.1021/Jo701475Q |
0.39 |
|
| 2007 |
Megha, Sawatzki P, Kolter T, Bittman R, London E. Effect of ceramide N-acyl chain and polar headgroup structure on the properties of ordered lipid domains (lipid rafts). Biochimica Et Biophysica Acta. 1768: 2205-12. PMID 17574203 DOI: 10.1016/J.Bbamem.2007.05.007 |
0.373 |
|
| 2007 |
Bittman R, Li Z, Samadder P, Arthur G. Anticancer activity of a ceramide analog containing a disulfide linkage. Cancer Letters. 251: 53-8. PMID 17141948 DOI: 10.1016/J.Canlet.2006.10.026 |
0.329 |
|
| 2007 |
Bittman R, Lu X, Song L, Metelitsa LS. A new {alpha}-C-galactosylceramide analog: promotion of Th1-biased responses in human CD1d-reactive V{alpha}24-invariant natural killer T cells The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A605-D |
0.507 |
|
| 2006 |
Lu X, Song L, Metelitsa LS, Bittman R. Synthesis and evaluation of an alpha-C-galactosylceramide analogue that induces Th1-biased responses in human natural killer T cells. Chembiochem : a European Journal of Chemical Biology. 7: 1750-6. PMID 17009272 DOI: 10.1002/Cbic.200600197 |
0.548 |
|
| 2006 |
Singh RD, Liu Y, Wheatley CL, Holicky EL, Makino A, Marks DL, Kobayashi T, Subramaniam G, Bittman R, Pagano RE. Caveolar endocytosis and microdomain association of a glycosphingolipid analog is dependent on its sphingosine stereochemistry. The Journal of Biological Chemistry. 281: 30660-8. PMID 16893900 DOI: 10.1074/Jbc.M606194200 |
0.532 |
|
| 2006 |
Baker DL, Fujiwara Y, Pigg KR, Tsukahara R, Kobayashi S, Murofushi H, Uchiyama A, Murakami-Murofushi K, Koh E, Bandle RW, Byun HS, Bittman R, Fan D, Murph M, Mills GB, et al. Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis. The Journal of Biological Chemistry. 281: 22786-93. PMID 16782709 DOI: 10.1074/Jbc.M512486200 |
0.324 |
|
| 2006 |
Nylund M, Kjellberg MA, Molotkovsky JG, Byun HS, Bittman R, Mattjus P. Molecular features of phospholipids that affect glycolipid transfer protein-mediated galactosylceramide transfer between vesicles. Biochimica Et Biophysica Acta. 1758: 807-12. PMID 16777057 DOI: 10.1016/J.Bbamem.2006.04.023 |
0.315 |
|
| 2006 |
Liu Y, Bittman R. Synthesis of fluorescent lactosylceramide stereoisomers. Chemistry and Physics of Lipids. 142: 58-69. PMID 16631151 DOI: 10.1016/J.Chemphyslip.2006.03.001 |
0.513 |
|
| 2006 |
Li Z, Mintzer E, Bittman R. First synthesis of free cholesterol-BODIPY conjugates Journal of Organic Chemistry. 71: 1718-1721. PMID 16468832 DOI: 10.1021/Jo052029X |
0.766 |
|
| 2006 |
Mintzer E, Sargsyan H, Bittman R. Lysophosphatidic acid and lipopolysaccharide bind to the PIP2-binding domain of gelsolin Biochimica Et Biophysica Acta - Biomembranes. 1758: 85-89. PMID 16460666 DOI: 10.1016/J.Bbamem.2005.12.009 |
0.728 |
|
| 2006 |
Li Z, Baker DL, Tigyi G, Bittman R. Synthesis of photoactivatable analogues of lysophosphatidic acid and covalent labeling of plasma proteins Journal of Organic Chemistry. 71: 629-635. PMID 16408973 DOI: 10.1021/Jo052030W |
0.322 |
|
| 2006 |
Shaw JE, Epand RF, Epand RM, Li Z, Bittman R, Yip CM. Correlated fluorescence-atomic force microscopy of membrane domains: structure of fluorescence probes determines lipid localization. Biophysical Journal. 90: 2170-8. PMID 16361347 DOI: 10.1529/Biophysj.105.073510 |
0.317 |
|
| 2006 |
Mehnert T, Jacob K, Bittman R, Beyer K. Structure and lipid interaction of N-palmitoylsphingomyelin in bilayer membranes as revealed by2H-NMR spectroscopy Biophysical Journal. 90: 939-946. PMID 16284259 DOI: 10.1529/Biophysj.105.063271 |
0.34 |
|
| 2006 |
Byun HS, Lu X, Bittman R. Stereoselective total synthesis of serine palmitoyl-CoA transferase inhibitors Synthesis. 2447-2474. DOI: 10.1055/S-2006-942475 |
0.568 |
|
| 2006 |
Lu X, Bittman R. Enantioselective synthesis of the phosphate esters of the immunosuppressive lipid FTY720 Tetrahedron Letters. 47: 825-827. DOI: 10.1016/J.Tetlet.2005.11.092 |
0.538 |
|
| 2005 |
Lu X, Bittman R. Synthesis of a photoactivatable (2S,3R)-sphingosylphosphorylcholine analogue. The Journal of Organic Chemistry. 70: 4746-50. PMID 15932314 DOI: 10.1021/Jo050513U |
0.594 |
|
| 2005 |
Lu X, Arthur G, Bittman R. Synthesis of a novel ceramide analogue via Tebbe methylenation and evaluation of its antiproliferative activity. Organic Letters. 7: 1645-8. PMID 15816773 DOI: 10.1021/Ol0503440 |
0.582 |
|
| 2005 |
Malewicz B, Valiyaveettil JT, Jacob K, Byun HS, Mattjus P, Baumann WJ, Bittman R, Brown RE. The 3-hydroxy group and 4,5-trans double bond of sphingomyelin are essential for modulation of galactosylceramide transmembrane asymmetry. Biophysical Journal. 88: 2670-80. PMID 15653730 DOI: 10.1529/Biophysj.104.057059 |
0.33 |
|
| 2005 |
Lu X, Bittman R. An efficient synthesis of D-ribo- and L-lyxo-phytosphingosine from D-tartaric acid Tetrahedron Letters. 46: 3165-3168. DOI: 10.1016/J.Tetlet.2005.03.063 |
0.528 |
|
| 2005 |
Lu X, Bittman R. Efficient and versatile synthesis of (2S,3R)-sphingosine and its 2-azido-3-O-benzylsphingosine analogue Tetrahedron Letters. 46: 1873-1875. DOI: 10.1016/J.Tetlet.2005.01.104 |
0.562 |
|
| 2004 |
Sun C, Bittman R. An efficient preparation of isosteric phosphonate analogues of sphingolipids by opening of oxirane and cyclic sulfamidate intermediates with α-lithiated alkylphosphonic esters Journal of Organic Chemistry. 69: 7694-7699. PMID 15497998 DOI: 10.1021/Jo0487404 |
0.345 |
|
| 2004 |
Brockman HL, Momsen MM, Brown RE, He L, Chun J, Byun HS, Bittman R. The 4,5-double bond of ceramide regulates its dipole potential, elastic properties, and packing behavior. Biophysical Journal. 87: 1722-31. PMID 15345551 DOI: 10.1529/Biophysj.104.044529 |
0.682 |
|
| 2004 |
Lu X, Byun HS, Bittman R. Synthesis of l-lyxo-phytosphingosine and its 1-phosphonate analogue using a threitol acetal synthon. The Journal of Organic Chemistry. 69: 5433-8. PMID 15287793 DOI: 10.1021/Jo0493065 |
0.576 |
|
| 2004 |
Li Z, Mintzer E, Bittman R. The critical micelle concentrations of lysophosphatidic acid and sphingosylphosphorylcholine Chemistry and Physics of Lipids. 130: 197-201. PMID 15172836 DOI: 10.1016/J.Chemphyslip.2004.03.001 |
0.732 |
|
| 2004 |
Bittman R. The 2003 ASBMB-Avanti Award in Lipids Address: Applications of novel synthetic lipids to biological problems Chemistry and Physics of Lipids. 129: 111-131. PMID 15081855 DOI: 10.1016/J.Chemphyslip.2004.01.004 |
0.384 |
|
| 2004 |
Zhang C, Baker DL, Yasuda S, Makarova N, Balazs L, Johnson LR, Marathe GK, McIntyre TM, Xu Y, Prestwich GD, Byun HS, Bittman R, Tigyi G. Lysophosphatidic acid induces neointima formation through PPARgamma activation. The Journal of Experimental Medicine. 199: 763-74. PMID 15007093 DOI: 10.1084/Jem.20031619 |
0.306 |
|
| 2004 |
Johnson CR, Chun J, Bittman R, Jarvis WD. Intrinsic cytotoxicity and chemomodulatory actions of novel phenethylisothiocyanate sphingoid base derivatives in HL-60 human promyelocytic leukemia cells. The Journal of Pharmacology and Experimental Therapeutics. 309: 452-61. PMID 14724218 DOI: 10.1124/Jpet.103.060665 |
0.584 |
|
| 2003 |
Crawford KW, Bittman R, Chun J, Byun HS, Bowen WD. Novel ceramide analogues display selective cytotoxicity in drug-resistant breast tumor cell lines compared to normal breast epithelial cells. Cellular and Molecular Biology (Noisy-Le-Grand, France). 49: 1017-23. PMID 14682383 |
0.523 |
|
| 2003 |
Lu X, Cseh S, Byun HS, Tigyi G, Bittman R. Total synthesis of two photoactivatable analogues of the growth-factor-like mediator sphingosine 1-phosphate: differential interaction with protein targets. The Journal of Organic Chemistry. 68: 7046-50. PMID 12946147 DOI: 10.1021/Jo034828Q |
0.57 |
|
| 2003 |
Singh RD, Puri V, Valiyaveettil JT, Marks DL, Bittman R, Pagano RE. Selective caveolin-1-dependent endocytosis of glycosphingolipids. Molecular Biology of the Cell. 14: 3254-65. PMID 12925761 DOI: 10.1091/Mbc.E02-12-0809 |
0.317 |
|
| 2003 |
Chun J, Byun HS, Arthur G, Bittman R. Synthesis and growth inhibitory activity of chiral 5-hydroxy-2-N-acyl-(3E)-sphingenines: ceramides with an unusual sphingoid backbone. The Journal of Organic Chemistry. 68: 355-9. PMID 12530860 DOI: 10.1021/Jo026242U |
0.594 |
|
| 2003 |
Chun J, Byun HS, Bittman R. First asymmetric synthesis of 6-hydroxy-4-sphingenine-containing ceramides. Use of chiral propargylic alcohols to prepare a lipid found in human skin. The Journal of Organic Chemistry. 68: 348-54. PMID 12530859 DOI: 10.1021/Jo026240+ |
0.599 |
|
| 2003 |
Merris M, Wadsworth WG, Khamrai U, Bittman R, Chitwood DJ, Lenard J. Sterol effects and sites of sterol accumulation in Caenorhabditis elegans: developmental requirement for 4alpha-methyl sterols. Journal of Lipid Research. 44: 172-81. PMID 12518036 DOI: 10.1194/Jlr.M200323-Jlr200 |
0.321 |
|
| 2002 |
Harris JR, Bhakdi S, Meissner U, Scheffler D, Bittman R, Li G, Zitzer A, Palmer M. Interaction of the Vibrio cholerae cytolysin (VCC) with cholesterol, some cholesterol esters, and cholesterol derivatives: a TEM study. Journal of Structural Biology. 139: 122-35. PMID 12406694 DOI: 10.1016/S1047-8477(02)00563-4 |
0.487 |
|
| 2002 |
Waarts BL, Bittman R, Wilschut J. Sphingolipid and cholesterol dependence of alphavirus membrane fusion: Lack of correlation with lipid raft formation in target liposomes Journal of Biological Chemistry. 277: 38141-38147. PMID 12138173 DOI: 10.1074/Jbc.M206998200 |
0.34 |
|
| 2002 |
Choi JK, Ho J, Curry S, Qin D, Bittman R, Hamilton JA. Interactions of very long-chain saturated fatty acids with serum albumin. Journal of Lipid Research. 43: 1000-10. PMID 12091483 DOI: 10.1194/Jlr.M200041-Jlr200 |
0.323 |
|
| 2002 |
Yokoyama K, Baker DL, Virag T, Liliom K, Byun HS, Tigyi G, Bittman R. Stereochemical properties of lysophosphatidic acid receptor activation and metabolism. Biochimica Et Biophysica Acta. 1582: 295-308. PMID 12069841 DOI: 10.1016/S1388-1981(02)00184-1 |
0.311 |
|
| 2002 |
Smit JM, Li G, Schoen P, Corver J, Bittman R, Lin KC, Wilschut J. Fusion of alphaviruses with liposomes is a non-leaky process. Febs Letters. 521: 62-6. PMID 12067727 DOI: 10.1016/S0014-5793(02)02823-5 |
0.403 |
|
| 2002 |
Chun J, Li G, Byun HS, Bittman R. Synthesis of new trans double-bond sphingolipid analogues: Delta(4,6) and Delta(6) ceramides. The Journal of Organic Chemistry. 67: 2600-5. PMID 11950306 DOI: 10.1021/Jo0162639 |
0.649 |
|
| 2002 |
Mintzer EA, Waarts BL, Wilschut J, Bittman R. Behavior of a photoactivatable analog of cholesterol, 6-photocholesterol, in model membranes. Febs Letters. 510: 181-4. PMID 11801250 DOI: 10.1016/S0014-5793(01)03271-9 |
0.771 |
|
| 2002 |
Chun J, Byun HS, Bittman R. Preparation of chiral propargylic alcohols from α,β-unsaturated esters Tetrahedron Letters. 43: 8043-8045. DOI: 10.1016/S0040-4039(02)01968-8 |
0.542 |
|
| 2002 |
Chun J, Li G, Byun HS, Bittman R. A concise route to D-erythro-sphingosine from N-Boc-L-serine derivatives via sulfoxide or sulfone intermediates Tetrahedron Letters. 43: 375-377. DOI: 10.1016/S0040-4039(01)02145-1 |
0.623 |
|
| 2001 |
Xu X, Bittman R, Duportail G, Heissler D, Vilcheze C, London E. Effect of the structure of natural sterols and sphingolipids on the formation of ordered sphingolipid/sterol domains (rafts). Comparison of cholesterol to plant, fungal, and disease-associated sterols and comparison of sphingomyelin, cerebrosides, and ceramide Journal of Biological Chemistry. 276: 33540-33546. PMID 11432870 DOI: 10.1074/Jbc.M104776200 |
0.338 |
|
| 2001 |
Yang G, Franck RW, Bittman R, Samadder P, Arthur G. Synthesis and growth inhibitory properties of glucosamine-derived glycerolipids. Organic Letters. 3: 197-200. PMID 11430033 DOI: 10.1021/Ol006783A |
0.572 |
|
| 2001 |
Zitzer A, Bittman R, Verbicky CA, Erukulla RK, Bhakdi S, Weis S, Valeva A, Palmer M. Coupling of cholesterol and cone-shaped lipids in bilayers augments membrane permeabilization by the cholesterol-specific toxins streptolysin O and Vibrio cholerae cytolysin. The Journal of Biological Chemistry. 276: 14628-33. PMID 11279036 DOI: 10.1074/Jbc.M100241200 |
0.372 |
|
| 2001 |
Zhong N, Ohvo-Rekilä H, Ramstedt B, Slotte JP, Bittman R. Selective Removal of Palmitic Acid from Langmuir Monolayers by Complexation with New Quaternary Ammonium β-Cyclodextrin Derivatives Langmuir. 17: 5319-5323. DOI: 10.1021/La010565O |
0.328 |
|
| 2001 |
Li G, Samadder P, Arthur G, Bittman R. Synthesis and antiproliferative properties of a photoactivatable analogue of ET-18-OCH3 Tetrahedron. 57: 8925-8932. DOI: 10.1016/S0040-4020(01)00901-2 |
0.514 |
|
| 2001 |
Bittman R, Qin D, Wong D, Tigyi G, Samadder P, Arthur G. Synthesis and antitumor properties of a plasmalogen methyl ether analogue Tetrahedron. 57: 4277-4282. DOI: 10.1016/S0040-4020(01)00371-4 |
0.334 |
|
| 2000 |
Chun J, He L, Byun HS, Bittman R. Synthesis of ceramide analogues having the C(4)-C(5) bond of the long-chain base as part of an aromatic or heteroaromatic system. The Journal of Organic Chemistry. 65: 7634-40. PMID 11076626 DOI: 10.1021/Jo001227F |
0.69 |
|
| 2000 |
He L, Byun HS, Bittman R. Stereoselective preparation of ceramide and its skeleton backbone modified analogues via cyclic thionocarbonate intermediates derived by catalytic asymmetric dihydroxylation of alpha,beta-unsaturated ester precursors. The Journal of Organic Chemistry. 65: 7627-33. PMID 11076625 DOI: 10.1021/Jo001226N |
0.545 |
|
| 2000 |
He L, Byun HS, Bittman R. A stereocontrolled, efficient synthetic route to bioactive sphingolipids: synthesis of phytosphingosine and phytoceramides from unsaturated ester precursors via cyclic sulfate intermediates. The Journal of Organic Chemistry. 65: 7618-26. PMID 11076624 DOI: 10.1021/Jo001225V |
0.572 |
|
| 2000 |
Yang G, Franck RW, Byun HS, Bittman R, Samadder P, Arthur G. Convergent C-glycolipid synthesis via the Ramberg-Bäcklund reaction: active antiproliferative glycolipids. Organic Letters. 1: 2149-51. PMID 10836068 DOI: 10.1021/Ol991211F |
0.578 |
|
| 2000 |
Qin D, Sullivan R, Berkowitz WF, Bittman R, Rotenberg SA. Inhibition of protein kinase Cα by dequalinium analogues: Dependence on linker length and geometry Journal of Medicinal Chemistry. 43: 1413-1417. PMID 10753478 DOI: 10.1021/Jm990340Z |
0.32 |
|
| 2000 |
Li G, Bittman R. Synthesis of novel phenoxy-linked diazirine glycero- and sphingolipid probes via trialkylaryltin intermediates Tetrahedron Letters. 41: 6737-6741. DOI: 10.1016/S0040-4039(00)01166-7 |
0.483 |
|
| 2000 |
Byun HS, He L, Bittman R. Cyclic sulfites and cyclic sulfates in organic synthesis Tetrahedron. 56: 7051-7091. DOI: 10.1016/S0040-4020(00)00494-4 |
0.502 |
|
| 1999 |
Lin W, Leung LW, Bae YS, Bittman R, Arthur G. Effects of a water-soluble antitumor ether phosphonoinositide, D-myo-inositol 4-(hexadecyloxy)-3(S)-methoxybutanephosphonate (C4-PI), on inositol lipid metabolism in breast epithelial cancer cell lines. Biochemical Pharmacology. 57: 1153-8. PMID 11230803 DOI: 10.1016/S0006-2952(99)00019-2 |
0.361 |
|
| 1999 |
Rozwarski DA, Vilchèze C, Sugantino M, Bittman R, Sacchettini JC. Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate. The Journal of Biological Chemistry. 274: 15582-9. PMID 10336454 DOI: 10.1074/Jbc.274.22.15582 |
0.33 |
|
| 1999 |
He L, Wanunu M, Byun HS, Bittman R. Regioselective and stereospecific azidation of 1,2- and 1,3-diols by azidotrimethylsilane via a Mitsunobu reaction Journal of Organic Chemistry. 64: 6049-6055. DOI: 10.1021/Jo9906375 |
0.525 |
|
| 1999 |
He L, Byun H, Smit J, Wilschut J, Bittman R. Enantioselective Synthesis of a Novel Trans Double Bond Ceramide Analogue via Catalytic Asymmetric Dihydroxylation of an Enyne. The Role of the Trans Double Bond of Ceramide in the Fusion of Semliki Forest Virus with Target Membranes Journal of the American Chemical Society. 121: 3897-3903. DOI: 10.1021/Ja981493Z |
0.388 |
|
| 1998 |
Jarvis WD, Fornari FA, Tombes RM, Erukulla RK, Bittman R, Schwartz GK, Dent P, Grant S. Evidence for involvement of mitogen-activated protein kinase, rather than stress-activated protein kinase, in potentiation of 1-β-D- arabinofuranosylcytosine-induced apoptosis by interruption of protein kinase C signaling Molecular Pharmacology. 54: 844-856. PMID 9804619 DOI: 10.1124/Mol.54.5.844 |
0.32 |
|
| 1998 |
Arthur G, Bittman R. The inhibition of cell signaling pathways by antitumor ether lipids Biochimica Et Biophysica Acta - Lipids and Lipid Metabolism. 1390: 85-102. PMID 9487143 DOI: 10.1016/S0005-2760(97)00163-X |
0.316 |
|
| 1998 |
Leung LW, Lin W, Richard C, Bittman R, Arthur G. A Novel Water-Soluble Phosphonate Analog of Phosphatidylinositol, D-Myo-Inositol4-(Hexadecyloxy)-3(5)-Methoxybutanephosphonate (C4-PI), Inhibits Epithelial Cell Proliferation and is a Substrate but not an Inhibitor of Phosphatidylinositol 3-Kinase Journal of Liposome Research. 8: 213-224. DOI: 10.3109/08982109809035527 |
0.312 |
|
| 1998 |
He L, Byun HS, Bittman R. A new synthetic route to chiral glycerolipid precursors using a cyclic sulfate synthon: Preparation of 1-o-hexadecyl-3-O-(4′-methoxyphenyl)-SN- glycerol and its 1-thio and 1-AZA analogues Journal of Organic Chemistry. 63: 5696-5699. DOI: 10.1021/Jo980471S |
0.525 |
|
| 1998 |
Byun HS, Sadlofsky JA, Bittman R. Enantioselective Synthesis of 3-Deoxy-(R)-sphingomyelin from (S)-1-(4′-Methoxyphenyl)glycerol Journal of Organic Chemistry. 63: 2560-2563. DOI: 10.1021/Jo971977Y |
0.334 |
|
| 1998 |
Leung LW, Vilchèze C, Bittman R. Synthesis of fluorescent phosphatidylinositols using a novel inositol H- phosphonate Tetrahedron Letters. 39: 2921-2924. DOI: 10.1016/S0040-4039(98)00418-3 |
0.301 |
|
| 1998 |
He L, Byun HS, Bittman R. Efficient synthesis of chiral α,β-epoxyesters via a cyclic sulfate intermediate Tetrahedron Letters. 39: 2071-2074. DOI: 10.1016/S0040-4039(98)00190-7 |
0.51 |
|
| 1997 |
Bittman R, Byun HS, Reddy KC, Samadder P, Arthur G. Enantioselective synthesis and antiproliferative properties of an ilmofosine analog, 2'-(trimethylammonio)ethyl 3-(hexadecyloxy)-2-(methoxymethyl)propyl phosphate, on epithelial cancer cell growth. Journal of Medicinal Chemistry. 40: 1391-5. PMID 9135036 DOI: 10.1021/Jm960165B |
0.32 |
|
| 1997 |
Bittman R. Has nature designed the cholesterol side chain for optimal interaction with phospholipids? Sub-Cellular Biochemistry. 28: 145-171. PMID 9090294 DOI: 10.1007/978-1-4615-5901-6_6 |
0.342 |
|
| 1996 |
Scarlata S, Gupta R, Garcia P, Keach H, Shah S, Kasireddy CR, Bittman R, Rebecchi MJ. Inhibition of phospholipase C-δ1 catalytic activity by sphingomyelin Biochemistry. 35: 14882-14888. PMID 8942652 DOI: 10.1021/Bi961072Z |
0.379 |
|
| 1996 |
Zhou X, Lu X, Richard C, Xiong W, Litchfield DW, Bittman R, Arthur G. 1-O-octadecyl-2-O-methyl-glycerophosphocholine inhibits the transduction of growth signals via the MAPK cascade in cultured MCF-7 cells. The Journal of Clinical Investigation. 98: 937-44. PMID 8770865 DOI: 10.1172/Jci118877 |
0.558 |
|
| 1996 |
Marino-Albernas JR, Bittman R, Peters A, Mayhew E. Synthesis and growth inhibitory properties of glycosides of 1-O- hexadecyl-2-O-methyl-sn-glycerol, analogs of the antitumor ether lipid ET- 18-OCH3 (edelfosine) Journal of Medicinal Chemistry. 39: 3241-3247. PMID 8765506 DOI: 10.1021/Jm960164J |
0.304 |
|
| 1996 |
Erukulla RK, Zhou X, Samadder P, Arthur G, Bittman R. Synthesis and Evaluation of the Antiproliferative Effects of 1-O-Hexadecyl-2-O- methyl-3-O-(2‘-acetamido-2‘-deoxy-β-d-glucopyranosyl)-sn-glycerol and 1-O-Hexadecyl-2-O-methyl-3-O-(2‘-amino-2‘-deoxy-β-d-glucopyranosyl)-sn-glycerol on Epithelial Cancer Cell Growth Journal of Medicinal Chemistry. 39: 1545-1548. PMID 8691486 DOI: 10.1021/Jm950928F |
0.311 |
|
| 1996 |
Jarvis WD, Fornari FA, Traylor RS, Martin HA, Kramer LB, Erukulla RK, Bittman R, Grant S. Induction of apoptosis and potentiation of ceramide-mediated cytotoxicity by sphingoid bases in human myeloid leukemia cells. The Journal of Biological Chemistry. 271: 8275-84. PMID 8626522 DOI: 10.1074/Jbc.271.14.8275 |
0.331 |
|
| 1996 |
Karasavvas N, Erukulla RK, Bittman R, Lockshin R, Zakeri Z. Stereospecific induction of apoptosis in U937 cells by N-octanoyl-sphingosine stereoisomers and N-octyl-sphingosine: The ceramide amide group is not required for apoptosis European Journal of Biochemistry. 236: 729-737. PMID 8612651 DOI: 10.1111/J.1432-1033.1996.00729.X |
0.316 |
|
| 1996 |
Vilchèze C, McMullen TP, McElhaney RN, Bittman R. The effect of side-chain analogues of cholesterol on the thermotropic phase behavior of 1-stearoyl-2-oleoylphosphatidylcholine bilayers: a differential scanning calorimetric study. Biochimica Et Biophysica Acta. 1279: 235-42. PMID 8603092 DOI: 10.1016/0005-2736(95)00258-8 |
0.346 |
|
| 1996 |
Mattjus P, Bittman R, Vilchèze C, Slotte JP. Lateral domain formation in cholesterol/phospholipid monolayers as affected by the sterol side chain conformation. Biochimica Et Biophysica Acta. 1240: 237-47. PMID 8541295 DOI: 10.1016/0005-2736(95)00179-4 |
0.325 |
|
| 1996 |
Mattjus P, Bittman R, Slotte JP. Molecular Interaction and Lateral Domain Formation in Monolayers Containing Cholesterol and Phosphatidylcholines with Acyl- or Alkyl-Linked C16 Chains Langmuir. 12: 1284-1290. DOI: 10.1021/La950861Z |
0.35 |
|
| 1996 |
Byun HS, Bittman R. Efficient stereospecific synthesis of diamide analogs of phosphatidylcholine starting from 1-(4′-methoxyphenyl)-sn-glycerol Journal of Organic Chemistry. 61: 8706-8708. DOI: 10.1021/Jo961422N |
0.313 |
|
| 1995 |
Lister MD, Ruan Zs, Bittman R. Interaction of sphingomyelinase with sphingomyelin analogs modified at the C-1 and C-3 positions of the sphingosine backbone Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 1256: 25-30. PMID 7742352 DOI: 10.1016/0005-2760(94)00249-X |
0.336 |
|
| 1995 |
Moesby L, Corver J, Erukulla RK, Bittman R, Wilschut J. Sphingolipids activate membrane fusion of Semliki Forest virus in a stereospecific manner. Biochemistry. 34: 10319-24. PMID 7654685 DOI: 10.1021/Bi00033A001 |
0.323 |
|
| 1995 |
Corver J, Moesby L, Erukulla RK, Reddy KC, Bittman R, Wilschut J. Sphingolipid-dependent fusion of Semliki Forest virus with cholesterol-containing liposomes requires both the 3-hydroxyl group and the double bond of the sphingolipid backbone. Journal of Virology. 69: 3220-3223. DOI: 10.1128/Jvi.69.5.3220-3223.1995 |
0.327 |
|
| 1995 |
Vilchèze C, Bittman R. Diacetylenic sterols: New potentially photopolymerizable lipids Journal of the Chemical Society, Perkin Transactions 1. 91: 2937-2940. DOI: 10.1039/P19950002937 |
0.355 |
|
| 1994 |
Lu X, Rengan K, Bittman R, Arthur G. The alpha-anomers and Beta-anomers of 1-o-hexadecyl-2-o-methyl-3-s-thioglucosyl-sn-glycerol inhibit the proliferation of epithelial cancer cell-lines. Oncology Reports. 1: 933-6. PMID 21607469 DOI: 10.3892/or.1.5.933 |
0.504 |
|
| 1994 |
Bittman R, Byun HS, Mercier B, Salari H. Isosteric phosphonate analogs of et-16-ome. synthesis and biological evaluation of the enantiomers of 2′-(trimethylammonio)ethyl 4-(hexadecyloxy)-3-methoxybutanephosphonate and 2′-(trimethylammonio)ethyl 4-(hexadecylthio)-3-methoxybutanephosphonate Journal of Medicinal Chemistry®. 37: 425-430. PMID 8308870 DOI: 10.1021/Jm00029A016 |
0.338 |
|
| 1994 |
Slotte JP, Jungner M, Vilchèze C, Bittman R. Effect of sterol side-chain structure on sterol-phosphatidylcholine interactions in monolayers and small unilamellar vesicles Bba - Biomembranes. 1190: 435-443. PMID 8142447 DOI: 10.1016/0005-2736(94)90105-8 |
0.334 |
|
| 1994 |
Bittman R. Interaction of cholesterol with sphingomyelin in monolayers and vesicles Biochemistry. 33: 11776-11781. PMID 7918394 DOI: 10.1021/Bi00205A013 |
0.368 |
|
| 1994 |
Jackson JK, Burt H, Mok W, Salari H, Kumar ER, Byun HS, Bittman R. A comparison of the lytic properties of two ether-linked lipids, one with and one without antineoplastic activity. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 72: 297-303. PMID 7893469 DOI: 10.1139/O94-042 |
0.34 |
|
| 1994 |
Rhodes DG, Hui SW, Xu YH, Byun HS, Singh M, Bittman R. Structure of polymerizable lipid bilayers VII: lateral organization of diacetylenic phosphatidylcholines with short proximal acyl chains. Biochimica Et Biophysica Acta. 1215: 237-44. PMID 7811706 DOI: 10.1016/0005-2760(94)90048-5 |
0.308 |
|
| 1994 |
Byun HS, Erukulla RK, Bittman R. Synthesis of sphingomyelin and ceramide 1-phosphate from ceramide without protection of the allylic hydroxyl group Journal of Organic Chemistry. 59: 6495-6498. DOI: 10.1021/Jo00100A069 |
0.31 |
|
| 1994 |
Byun HS, Bittman R. Stereospecific synthesis of thioether glycerophospholipids. Catalytic asymmetric epoxidation followed by in situ borohydride-mediated opening of glycidol with hexadecylmercaptan Journal of Organic Chemistry. 59: 668-671. DOI: 10.1021/Jo00082A030 |
0.302 |
|
| 1994 |
Kumar Erukulla R, Byun HS, Bittman R. Antitumor phospholipids: A one-pot introduction of a phosphocholine moiety into lipid hydroxy acceptors Tetrahedron Letters. 35: 5783-5784. DOI: 10.1016/S0040-4039(00)78183-4 |
0.362 |
|
| 1994 |
Chandraprakash Reddy K, Byun HS, Bittman R. Antitumor ether lipids: An improved synthesis of ilmofosine and an enantioselective synthesis of an ilmofosine analog Tetrahedron Letters. 35: 2679-2682. DOI: 10.1016/S0040-4039(00)77004-3 |
0.34 |
|
| 1994 |
Kumar ER, Byun HS, Wang S, Bittman R. Preparation of ether-linked 2-acetamido-2-deoxy β-glycolipids via zinc chloride promoted coupling of Ac4GlcNAcCl with lipid hydroxy groups Tetrahedron Letters. 35: 505-508. DOI: 10.1016/S0040-4039(00)75823-0 |
0.321 |
|
| 1993 |
Salari H, Low M, Howard S, Edin G, Bittman R. 1-O-hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine inhibits diacylglycerol kinase in WEHI-3B cells. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 71: 36-42. PMID 8392354 DOI: 10.1139/O93-006 |
0.318 |
|
| 1993 |
Bittman R. Mycoplasma membrane lipids. Chemical composition and transbilayer distribution Sub-Cellular Biochemistry. 20: 29-52. PMID 8378993 DOI: 10.1007/978-1-4615-2924-8_2 |
0.303 |
|
| 1993 |
Slotte JP, Östman AL, Kumar ER, Bittman R. Cholesterol interacts with lactosyl and maltosyl cerebrosides but not with glucosyl or galactosyl cerebrosides in mixed monolayers Biochemistry. 32: 7886-7892. PMID 8347594 DOI: 10.1021/Bi00082A008 |
0.349 |
|
| 1993 |
Byun HS, Bittman R. A one-pot synthesis of dimethyl 2, 3-o-bmjwwenzylidene-l-tartrate from l-tartaric acid Synthetic Communications. 23: 3201-3204. DOI: 10.1080/00397919308011180 |
0.303 |
|
| 1993 |
Chia NC, Vilchèze C, Bittman R, Mendelsohn R. Interactions of cholesterol and synthetic sterols with phosphatidylcholines As deduced from infrared CH2 wagging progression intensities Journal of the American Chemical Society. 115: 12050-12055. DOI: 10.1021/Ja00078A049 |
0.343 |
|
| 1993 |
Berkowitz WF, Pan D, Bittman R. A new approach to archaebacterial lipid models Tetrahedron Letters. 34: 4297-4300. DOI: 10.1016/S0040-4039(00)79333-6 |
0.307 |
|
| 1992 |
Kan CC, Yan J, Bittman R. Rates of spontaneous exchange of synthetic radiolabeled sterols between lipid vesicles Biochemistry. 31: 1866-1874. PMID 1737039 DOI: 10.1021/Bi00121A040 |
0.33 |
|
| 1992 |
Bittman R, Fugler L, Clejan S, Lister MD, Hancock AJ. Interaction of cholesterol with conformationally restricted phospholipids in vesicles. Biochimica Et Biophysica Acta. 1106: 40-4. PMID 1581334 DOI: 10.1016/0005-2736(92)90219-C |
0.358 |
|
| 1992 |
Salari H, Dryden P, Davenport R, Howard S, Jones K, Bittman R. Inhibition of protein kinase C by ether-linked lipids is not correlated with their antineoplastic activity on WEHI-3B and R6X-B15 cells. Biochimica Et Biophysica Acta. 1134: 81-8. PMID 1543759 DOI: 10.1016/0167-4889(92)90030-F |
0.344 |
|
| 1992 |
Salari H, Howard S, Bittman R. Synthesis and antineoplastic properties of an ether glycerophosphonocholine, an analog of ET-18-OCH3-GPC Biochemical and Biophysical Research Communications. 187: 603-608. PMID 1530618 DOI: 10.1016/0006-291X(92)91237-K |
0.344 |
|
| 1992 |
Rhodes DG, Xu Z, Bittman R. Structure of polymerizable lipid bilayers. V: synthesis, bilayer structure and properties of diacetylenic ether and ester lipids Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 1128: 93-104. PMID 1390881 DOI: 10.1016/0005-2760(92)90262-T |
0.35 |
|
| 1992 |
Salari H, Dryden P, Howard S, Bittman R. Two different sites of action for platelet activating factor and 1-O-alkyl-2-O-methyl-sn-glycero-3-phosphocholine on platelets and leukemic cells Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 70: 129-135. PMID 1324692 DOI: 10.1139/O92-019 |
0.354 |
|
| 1991 |
Kan CC, Bittman R, Hajdu J. Phospholipids containing nitrogen- and sulfur-linked chains: kinetics of cholesterol exchange between vesicles Bba - Biomembranes. 1066: 95-101. PMID 2065074 DOI: 10.1016/0005-2736(91)90256-8 |
0.366 |
|
| 1991 |
Kan CC, Bittman R. Spontaneous rates of sitosterol and cholesterol exchange between phospholipid vesicles and between lysophospholipid dispersions: Evidence that desorption rate is impeded by the 24α-ethyl group of sitosterol Journal of the American Chemical Society. 113: 6650-6656. DOI: 10.1021/Ja00017A043 |
0.362 |
|
| 1990 |
Guivisdalsky PN, Bittman R, Smith Z, Blank ML, Snyder F, Howard S, Salari H. Synthesis and antineoplastic properties of ether-linked thioglycolipids. Journal of Medicinal Chemistry. 33: 2614-21. PMID 2391700 DOI: 10.1021/Jm00171A042 |
0.317 |
|
| 1990 |
Ali S, Bittman R. Synthesis of optically active 1-acyl-2-O-alkyl-sn-glycero-3-phosphocholine via 1-O-benzyl-sn-glycerol 3-arenesulfonate Biochemistry and Cell Biology. 68: 360-365. PMID 2350497 DOI: 10.1139/O90-049 |
0.323 |
|
| 1990 |
Halladay HN, Stark RE, Ali S, Bittman R. Magic-angle spinning NMR studies of molecular organization in multibilayers formed by 1-octadecanoyl-2-decanoyl-sn-glycero-3-phosphocholine Biophysical Journal. 58: 1449-1461. PMID 2275962 DOI: 10.1016/S0006-3495(90)82490-5 |
0.302 |
|
| 1989 |
Bittman R, Witzke NM. Conversion of methylallyl alcohol into C2-methyl-1,2-di-O-hexadecylglycerophosphocholine, a conformationally restricted phospholipid Chemistry and Physics of Lipids. 50: 99-103. PMID 2766429 DOI: 10.1016/0009-3084(89)90032-7 |
0.363 |
|
| 1989 |
Pugh EL, Bittman R, Fugler L, Kates M. Comparison of steady-state fluorescence polarization and urea permeability of phosphatidylcholine and phosphatidylsulfocholine liposomes as a function of sterol structure Chemistry and Physics of Lipids. 50: 43-50. PMID 2758524 DOI: 10.1016/0009-3084(89)90024-8 |
0.359 |
|
| 1989 |
Ali S, Bittman R. Mixed-chain phosphatidylcholine analogues modified in the choline moiety: preparation of isomerically pure phospholipids with bulky head groups and one acyl chain twice as long as the other Chemistry and Physics of Lipids. 50: 11-21. PMID 2758523 DOI: 10.1016/0009-3084(89)90022-4 |
0.356 |
|
| 1989 |
Guivisdalsky PN, Bittman R. An efficient stereocontrolled route to both enantiomers of platelet activating factor and analogues with long-chain esters at C2: Saturated and unsaturated ether glycerolipids by opening of glycidyl arenesulfonates Journal of Organic Chemistry. 54: 4643-4648. DOI: 10.1021/Jo00280A035 |
0.356 |
|
| 1989 |
Guivisdalsky PN, Bittman R. Regiospecific opening of glycidyl derivatives mediated by boron trifluoride. Asymmetric synthesis of ether-linked phospholipids Journal of Organic Chemistry. 54: 4637-4642. DOI: 10.1021/Jo00280A034 |
0.335 |
|
| 1989 |
Guivisdalsky PN, Bittman R. Glycidyl derivatives as chiral C3 synthons. Ring opening catalyzed by boron trifluoride etherate Journal of the American Chemical Society. 111: 3077-3079. DOI: 10.1021/Ja00190A059 |
0.308 |
|
| 1986 |
Bittman R, Clejan S, Fugler L, Rosenthal AF. The effect of cholesterol on glycerophosphono- and glycerophosphinocholines. Permeability measurements in lipid vesicles Bba - Biomembranes. 855: 265-270. PMID 3947623 DOI: 10.1016/0005-2736(86)90173-2 |
0.339 |
|
| 1986 |
Bittman R, Blau L. Permeability behavior of liposomes prepared from fatty acids and fatty acid methyl esters Bba - Biomembranes. 863: 115-120. PMID 3778908 DOI: 10.1016/0005-2736(86)90393-7 |
0.306 |
|
| 1986 |
Lewis EN, Bittman R, Levin IW. Methyl group substitution at C(1), C(2) or C(3) of the glycerol backbone of a diether phosphocholine: a comparative study of bilayer chain disorder in the gel and liquid-crystalline phases. Biochimica Et Biophysica Acta. 861: 44-52. PMID 3756154 DOI: 10.1016/0005-2736(86)90401-3 |
0.315 |
|
| 1985 |
Bittman R, Clejan S, Robinson BP, Witzke NM. Kinetics of cholesterol and phospholipid exchange from membranes containing cross-linked proteins or cross-linked phosphatidylethanolamines Biochemistry. 24: 1403-1409. PMID 3986182 DOI: 10.1021/Bi00327A018 |
0.362 |
|
| 1984 |
Bittman R, Clejan S, Lund-Katz S, Phillips MC. Influence of cholesterol on bilayers of ester- and ether-linked phospholipids Permeability and 13C-nuclear magnetic resonance measurements Bba - Biomembranes. 772: 117-126. PMID 6722139 DOI: 10.1016/0005-2736(84)90034-8 |
0.373 |
|
| 1984 |
Witzke NM, Bittman R. Dissociation kinetics and equilibrium binding properties of polyene antibiotic complexes with phosphatidylcholine/sterol vesicles Biochemistry. 23: 1668-1674. PMID 6722119 DOI: 10.1021/Bi00303A014 |
0.307 |
|
| 1984 |
ROBINSON BP, CLEJAN S, BITTMAN R. Effects of Cross-linking of Membrane Components on Cholesterol and Phospholipid Translocation Annals of the New York Academy of Sciences. 435: 572-574. DOI: 10.1111/J.1749-6632.1984.Tb13887.X |
0.306 |
|
| 1984 |
Bittman R, Rosenthal AF, Vargas LA. Synthesis of phospholipids via dimethylphosphoryl chloride Chemistry and Physics of Lipids. 34: 201-205. DOI: 10.1016/0009-3084(84)90044-6 |
0.333 |
|
| 1982 |
Blau L, Bittman R, Lagocki P, Byrne R, Scanu AM. Organization of unesterified cholesterol in high density lipoproteins probed by filipin. Biochimica Et Biophysica Acta. 712: 437-43. PMID 6812643 DOI: 10.1016/0005-2760(82)90270-3 |
0.31 |
|
| 1982 |
Gross Z, Rottem S, Bittman R. Phospholipid interconversions in Mycoplasma capricolum European Journal of Biochemistry. 122: 169-174. PMID 6277632 DOI: 10.1111/J.1432-1033.1982.Tb05863.X |
0.343 |
|
| 1982 |
Levin IW, Mushayakarara E, Bittman R. Vibrational assignment of the sn-1 and sn-2 chain carbonyl stretching modes of membrane phospholipids Journal of Raman Spectroscopy. 13: 231-234. DOI: 10.1002/Jrs.1250130306 |
0.31 |
|
| 1981 |
Rottem S, Shinar D, Bittman R. Symmetrical distribution and rapid transbilayer movement of cholesterol in Mycoplasma gallisepticum membranes Bba - Biomembranes. 649: 572-580. PMID 7317418 DOI: 10.1016/0005-2736(81)90161-9 |
0.341 |
|
| 1981 |
Bittman R, Blau L, Clejan S, Rottem S. Determination of cholesterol asymmetry by rapid kinetics of filipin-cholesterol association: effect of modification in lipids and proteins. Biochemistry. 20: 2425-32. PMID 7236612 DOI: 10.1021/Bi00512A009 |
0.356 |
|
| 1981 |
Clejan S, Bittman R, Rottem S. Effects of sterol structure and exogenous lipids on the transbilayer distribution of sterols in the membrane of Mycoplasma capricolum Biochemistry. 20: 2200-2204. PMID 7236590 DOI: 10.1021/Bi00511A019 |
0.341 |
|
| 1981 |
Bittman R, Leventhal A, Karp S, Blau L, Tremblay P, Kates M. Osmotic behavior of liposomes of phosphatidylcholine and phosphatidylsulfocholine as a function of lipid concentration Chemistry and Physics of Lipids. 28: 323-335. DOI: 10.1016/0009-3084(81)90018-9 |
0.358 |
|
| 1978 |
Rottem S, Slutzky GM, Bittman R. Cholesterol distribution and movement in the mycoplasma gallisepticum cell membrane Biochemistry. 17: 2723-2726. PMID 210781 DOI: 10.1021/Bi00607A005 |
0.358 |
|
| 1977 |
Chen WC, Bittman R. Kinetics of association of amphotericin B with vesicles Biochemistry. 16: 4145-4149. PMID 901763 DOI: 10.1021/Bi00638A002 |
0.331 |
|
| 1977 |
Blau L, Bittman R. Interaction of filipin with cholesterol in vesicles of saturated phospholipids Biochemistry. 16: 4139-4144. PMID 901762 DOI: 10.1021/Bi00638A001 |
0.329 |
|
| 1977 |
Majuk Z, Bittman R, Landsberger FR, Compans RW. Effects of filipin on the structure and biological activity of enveloped viruses Journal of Virology. 24: 883-892. PMID 201781 DOI: 10.1128/Jvi.24.3.883-892.1977 |
0.326 |
|
| 1976 |
Deroo PW, Rosenthal AF, Isaacson YA, Vargas LA, Bittman R. Synthesis of DL-2,3-diacyloxypropylphosphonyl-cholines from DL-2,3-diacyloxyiodopropanes. Chemistry and Physics of Lipids. 16: 60-70. PMID 1260961 DOI: 10.1016/0009-3084(76)90014-1 |
0.322 |
|
| 1976 |
Bittman R, Rottem S. Distribution of cholesterol between the outer and inner halves of the lipid bilayer of mycoplasma cell membranes Biochemical and Biophysical Research Communications. 71: 318-324. PMID 962923 DOI: 10.1016/0006-291X(76)90285-0 |
0.338 |
|
| 1975 |
Rosenthol AF, Vargas LA, Isaacson YA, Bittman R. A simple synthesis of phosphonate - containing lipids. Introduction of the phosphonic acid moiety into hydrolytically-labile compounds Tetrahedron Letters. 16: 977-980. DOI: 10.1016/S0040-4039(00)72621-9 |
0.355 |
|
| 1974 |
Bittman R, Chen WC, Blau L. Stopped-flow kinetic and equilibrium studies of filipin III binding to sterols Biochemistry. 13: 1374-1379. PMID 4819754 DOI: 10.1021/Bi00704A010 |
0.32 |
|
| 1972 |
Bittman R, Blau L. The phospholipid-cholesterol interaction. Kinetics of water permeability in liposomes Biochemistry. 11: 4831-4839. PMID 4655255 DOI: 10.1021/Bi00775A029 |
0.342 |
|
| 1972 |
Bittman R, Fischkoff SA. Fluorescence studies of the binding of the polyene antibiotics filipin 3, amphotericin B, nystatin, and lagosin to cholesterol Proceedings of the National Academy of Sciences of the United States of America. 69: 3795-3799. PMID 4509341 DOI: 10.1073/Pnas.69.12.3795 |
0.316 |
|
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