| Year |
Citation |
Score |
| 2020 |
Armstrong AE, Rhodes SD, Smith A, Chen S, Bessler W, Ferguson MJ, Jiang L, Li X, Yuan J, Yang X, Yang FC, Robertson KA, Ingram DA, Blakeley JO, Clapp DW. Early administration of imatinib mesylate reduces plexiform neurofibroma tumor burden with durable results after drug discontinuation in a mouse model of neurofibromatosis type 1. Pediatric Blood & Cancer. e28372. PMID 32459399 DOI: 10.1002/pbc.28372 |
0.569 |
|
| 2019 |
Man N, Mas Martin G, Karl D, Sun J, Liu F, Torres-Martin M, Itonaga H, Martinez C, Chen S, Duffort S, Hamard P, Xu Y, Cimmino L, Yang F, Cole PA, et al. EP300 Suppresses Leukemia Development in Myelodysplastic Syndrome through Myb Repression Blood. 134: 561-561. DOI: 10.1182/Blood-2019-130507 |
0.332 |
|
| 2018 |
Zhang L, Sultana N, Yan J, Yang F, Chen F, Chepurko E, Yang FC, Du Q, Zangi L, Xu M, Bu L, Cai CL. Cardiac Sca-1 Cells Are Not Intrinsic Stem Cells for Myocardial Development, Renewal, and Repair. Circulation. 138: 2919-2930. PMID 30566018 DOI: 10.1161/Circulationaha.118.035200 |
0.341 |
|
| 2018 |
Zhang P, He F, Bai J, Yamamoto S, Chen S, Zhang L, Sheng M, Zhang L, Guo Y, Man N, Yang H, Wang S, Cheng T, Nimer SD, Zhou Y, ... ... Yang FC, et al. Chromatin regulator Asxl1 loss and Nf1 halpoinsufficiency cooperate to accelerate myeloid malignancy. The Journal of Clinical Investigation. PMID 30226831 DOI: 10.1172/JCI121366 |
0.329 |
|
| 2018 |
Shi H, Wang Y, Li R, Xing W, Yang FC, Bai J, Zhou Y. Alteration in the Cytokine Secretion of Bone Marrow Stromal Cells from Patients with Chronic Myelomonocytic Leukemia Contribute to Impaired Hematopoietic Supportive Activity. Stem Cells International. 2018: 5921392. PMID 30123289 DOI: 10.1155/2018/5921392 |
0.319 |
|
| 2018 |
Chu Y, Zhao Z, Wayne Sant D, Zhu G, Greenblatt SM, Liu L, Wang J, Cao Z, Cheng Tho J, Chen S, Liu X, Zhang P, Maciejewski JP, Nimer S, Wang G, ... ... Yang FC, et al. Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC). Genomics, Proteomics & Bioinformatics. PMID 29908294 DOI: 10.1016/J.Gpb.2018.04.005 |
0.374 |
|
| 2018 |
Zhang P, Chen Z, Li R, Guo Y, Shi H, Bai J, Yang H, Sheng M, Li Z, Li Z, Li J, Chen S, Yuan W, Cheng T, Xu M, ... ... Yang FC, et al. Loss of ASXL1 in the bone marrow niche dysregulates hematopoietic stem and progenitor cell fates. Cell Discovery. 4: 4. PMID 29423272 DOI: 10.1038/s41421-017-0004-z |
0.383 |
|
| 2018 |
Chu Y, Chen Y, Guo H, Li M, Shi J, Cheng T, Yang F, Xu M, Yuan W. Suv39h1 Represses the Progression of MLL-Rearranged Myeloid Leukemia Via Hoxb13 Blood. 132: 3878-3878. DOI: 10.1182/blood-2018-99-113732 |
0.325 |
|
| 2018 |
Zhu G, Luo H, Chen S, Lai Q, Guo Y, Guryanova OA, Qiu Y, Yang F, Li W, Nimer SD, Huang S, Xu M. Hoxblinc Is Aberrantly Expressed in Acute Myeloid Leukemia and Functions As a Potent Oncogenic Long Non-Coding RNA in Leukemogenesis Blood. 132: 886-886. DOI: 10.1182/Blood-2018-99-112232 |
0.315 |
|
| 2018 |
Zhang P, He F, Bai J, Chen S, Nimer SD, Zhou Y, Xu M, Wang Q, Yang F. Cooperative Epigenetic Regulation By ASXL1 and NF1 Loss on Leukemogenesis Blood. 132: 652-652. DOI: 10.1182/Blood-2018-99-110964 |
0.457 |
|
| 2018 |
Luo H, Zhu G, Zha J, Yan B, Guo Y, Xu J, Lai Q, Xu B, Yang F, Li W, Qiu Y, Xu M, Huang S. Activation of Hottip lncrna Perturbs HSC Function Leading to AML like Disease in Mice Blood. 132: 3877-3877. DOI: 10.1182/Blood-2018-99-110218 |
0.391 |
|
| 2017 |
Li R, Zhou Y, Cao Z, Liu L, Wang J, Chen Z, Xing W, Chen S, Bai J, Yuan W, Cheng T, Xu M, Yang FC, Zhao Z. TET2 Loss Dysregulates the Behavior of Bone Marrow Mesenchymal Stromal Cells and Accelerates Tet2-/--Driven Myeloid Malignancy Progression. Stem Cell Reports. PMID 29290626 DOI: 10.1016/j.stemcr.2017.11.019 |
0.377 |
|
| 2017 |
Yang H, Kurtenbach S, Guo Y, Lohse I, Durante MA, Li J, Li Z, Al-Ali H, Li L, Chen Z, Field MG, Zhang P, Chen S, Yamamoto S, Li Z, ... ... Yang FC, et al. Gain-of-function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies. Blood. PMID 29113963 DOI: 10.1182/Blood-2017-06-789669 |
0.329 |
|
| 2017 |
Shao Y, Hernandez-Buquer S, Childress P, Stayrook KR, Alvarez MB, Davis H, Plotkin L, He Y, Condon KW, Burr DB, Warden SJ, Robling AG, Yang FC, Wek RC, Allen MR, et al. Improving Combination Osteoporosis Therapy In a Preclinical Model of Heightened Osteoanabolism. Endocrinology. PMID 28637206 DOI: 10.1210/En.2017-00355 |
0.313 |
|
| 2017 |
Li J, He F, Zhang P, Chen S, Shi H, Sun Y, Guo Y, Yang H, Man N, Greenblatt S, Li Z, Guo Z, Zhou Y, Wang L, Morey L, ... ... Yang FC, et al. Loss of Asxl2 leads to myeloid malignancies in mice. Nature Communications. 8: 15456. PMID 28593990 DOI: 10.1038/Ncomms15456 |
0.389 |
|
| 2017 |
Zhou Y, He Y, Xing W, Zhang P, Shi H, Chen S, Shi J, Bai J, Rhodes SD, Zhang F, Yuan J, Yang X, Zhu X, Li Y, Hanenberg H, ... ... Yang FC, et al. Abnormal bone marrow microenvironment contributes to hematopoietic dysfunction in Fanconi anemia. Haematologica. PMID 28341737 DOI: 10.3324/Haematol.2016.158717 |
0.612 |
|
| 2017 |
Li Z, Zhang P, Yan A, Guo Z, Ban Y, Li J, Chen S, Yang H, He Y, Li J, Guo Y, Zhang W, Hajiramezanali E, An H, Fajardo D, ... ... Yang FC, et al. ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis. Science Advances. 3: e1601602. PMID 28116354 DOI: 10.1126/Sciadv.1601602 |
0.363 |
|
| 2016 |
Zhang P, Xing C, Rhodes SD, He Y, Deng K, Li Z, He F, Zhu C, Nguyen L, Zhou Y, Chen S, Mohammad KS, Guise TA, Abdel-Wahab O, Xu M, ... ... Yang FC, et al. Loss of Asxl1 Alters Self-Renewal and Cell Fate of Bone Marrow Stromal Cell, Leading to Bohring-Opitz-like Syndrome in Mice. Stem Cell Reports. PMID 27237378 DOI: 10.1016/J.Stemcr.2016.04.013 |
0.614 |
|
| 2016 |
Rhodes SD, Yang FC. Aberrant Myeloid Differentiation Contributes to the Development of Osteoporosis in Neurofibromatosis Type 1. Current Osteoporosis Reports. 14: 10-5. PMID 26932441 DOI: 10.1007/s11914-016-0298-z |
0.654 |
|
| 2016 |
Zhao Z, Li R, Liu L, Wang J, Chen Z, Xing W, Yuan W, Yang F, Zhou Y, Xu M. Tet2 Loss Dysregulates the Behavior of Mesenchymal Stem Cells and Increases Their Ability to Promote Tet2-/--Driven Myeloid Malignancy Progression Blood. 128: 1510-1510. DOI: 10.1182/blood.v128.22.1510.1510 |
0.386 |
|
| 2016 |
Li J, He F, Zhang P, Chen S, Shi H, Sun Y, Ying G, Yang H, Nimer SD, Wang Q, Xu M, Yang F. ASXL2 Is Required for Normal Hematopoiesis and Loss of asxl2 Leads to Myeloid Malignancies in Mice Blood. 128: 1509-1509. DOI: 10.1182/blood.v128.22.1509.1509 |
0.396 |
|
| 2015 |
Ferguson MJ, Rhodes SD, Jiang L, Li X, Yuan J, Yang X, Zhang S, Vakili ST, Territo P, Hutchins G, Yang FC, Ingram DA, Clapp DW, Chen S. Preclinical evidence for the use of sunitinib malate in the treatment of plexiform neurofibromas. Pediatric Blood & Cancer. PMID 26375012 DOI: 10.1002/Pbc.25763 |
0.584 |
|
| 2015 |
Childress P, Stayrook KR, Alvarez MB, Wang Z, Shao Y, Hernandez-Buquer S, Mack JK, Grese ZR, He Y, Horan D, Pavalko FM, Warden SJ, Robling AG, Yang FC, Allen MR, et al. Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis. Molecular Endocrinology (Baltimore, Md.). 29: 1269-85. PMID 26244796 DOI: 10.1210/Me.2014-1406 |
0.382 |
|
| 2015 |
Zhou Y, He Y, Sharma R, Xing W, Estwick SA, Wu X, Rhodes SD, Xu M, Yang FC. Hyperactive RAS/PI3-K/MAPK Signaling Cascade in Migration and Adhesion of Nf1 Haploinsufficient Mesenchymal Stem/Progenitor Cells. International Journal of Molecular Sciences. 16: 12345-59. PMID 26039236 DOI: 10.3390/Ijms160612345 |
0.638 |
|
| 2015 |
Rhodes SD, Yang H, Dong R, Menon K, He Y, Li Z, Chen S, Staser KW, Jiang L, Wu X, Yang X, Peng X, Mohammad KS, Guise TA, Xu M, ... Yang FC, et al. Nf1 Haploinsufficiency Alters Myeloid Lineage Commitment and Function, Leading to Deranged Skeletal Homeostasis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 25917016 DOI: 10.1002/Jbmr.2538 |
0.665 |
|
| 2015 |
Rhodes SD, Zhang W, Yang D, Yang H, Chen S, Wu X, Li X, Yang X, Mohammad KS, Guise TA, Bergner AL, Stevenson DA, Yang FC. Dystrophic spinal deformities in a neurofibromatosis type 1 murine model. Plos One. 10: e0119093. PMID 25786243 DOI: 10.1371/Journal.Pone.0119093 |
0.607 |
|
| 2015 |
Gehlhausen JR, Park SJ, Hickox AE, Shew M, Staser K, Rhodes SD, Menon K, Lajiness JD, Mwanthi M, Yang X, Yuan J, Territo P, Hutchins G, Nalepa G, Yang FC, et al. A murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formation. Human Molecular Genetics. 24: 1-8. PMID 25113746 DOI: 10.1093/Hmg/Ddu414 |
0.568 |
|
| 2015 |
Yamamoto S, Shi H, Chen S, Zhang P, Zhou Y, Xu M, Yang F. ASXL1 Is a Key Regulator for Erythroid Development and Asxl1 Loss Impairs Erythropoiesis In Vivo Blood. 126: 3644-3644. DOI: 10.1182/blood.v126.23.3644.3644 |
0.359 |
|
| 2015 |
Nabinger SC, Kobayashi M, Gao R, Chen S, Yao C, Yang F, Liu Y. Mutant p53 Drives the Development of Pre-Leukemic Hematopoietic Stem Cells through Modulating Epigenetic Regulators Blood. 126: 307-307. DOI: 10.1182/blood.V126.23.307.307 |
0.37 |
|
| 2015 |
Zhang P, Yamamoto S, Chen S, Zhou Y, Xu M, Yang F. Cooperative Effect of Haploinsufficient ASXL1 and NF1 in Acute Myeloid Leukemia Transformation Blood. 126: 1224-1224. DOI: 10.1182/blood.v126.23.1224.1224 |
0.421 |
|
| 2014 |
Li Y, Xing W, He YZ, Chen S, Rhodes SD, Yuan J, Zhou Y, Shi J, Bai J, Zhang FK, Yuan WP, Cheng T, Xu MJ, Yang FC. Interleukin 8/KC enhances G-CSF induced hematopoietic stem/progenitor cell mobilization in Fancg deficient mice. Stem Cell Investigation. 1: 19. PMID 27358865 DOI: 10.3978/J.Issn.2306-9759.2014.10.02 |
0.627 |
|
| 2014 |
Wang J, Li Z, He Y, Pan F, Chen S, Rhodes S, Nguyen L, Yuan J, Jiang L, Yang X, Weeks O, Liu Z, Zhou J, Ni H, Cai CL, ... ... Yang FC, et al. Loss of Asxl1 leads to myelodysplastic syndrome-like disease in mice. Blood. 123: 541-53. PMID 24255920 DOI: 10.1182/Blood-2013-05-500272 |
0.599 |
|
| 2013 |
Sharma R, Wu X, Rhodes SD, Chen S, He Y, Yuan J, Li J, Yang X, Li X, Jiang L, Kim ET, Stevenson DA, Viskochil D, Xu M, Yang FC. Hyperactive Ras/MAPK signaling is critical for tibial nonunion fracture in neurofibromin-deficient mice. Human Molecular Genetics. 22: 4818-28. PMID 23863460 DOI: 10.1093/Hmg/Ddt333 |
0.651 |
|
| 2013 |
Nalepa G, Barnholtz-Sloan J, Enzor R, Dey D, He Y, Gehlhausen JR, Lehmann AS, Park SJ, Yang Y, Yang X, Chen S, Guan X, Chen Y, Renbarger J, Yang FC, et al. The tumor suppressor CDKN3 controls mitosis. The Journal of Cell Biology. 201: 997-1012. PMID 23775190 DOI: 10.1083/Jcb.201205125 |
0.31 |
|
| 2013 |
Rhodes SD, Wu X, He Y, Chen S, Yang H, Staser KW, Wang J, Zhang P, Jiang C, Yokota H, Dong R, Peng X, Yang X, Murthy S, Azhar M, ... ... Yang FC, et al. Hyperactive transforming growth factor-β1 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 2476-89. PMID 23703870 DOI: 10.1002/Jbmr.1992 |
0.631 |
|
| 2013 |
Stevenson DA, Little D, Armstrong L, Crawford AH, Eastwood D, Friedman JM, Greggi T, Gutierrez G, Hunter-Schaedle K, Kendler DL, Kolanczyk M, Monsell F, Oetgen M, Richards BS, Schindeler A, ... ... Yang FC, et al. Approaches to treating NF1 tibial pseudarthrosis: consensus from the Children's Tumor Foundation NF1 Bone Abnormalities Consortium. Journal of Pediatric Orthopedics. 33: 269-75. PMID 23482262 DOI: 10.1097/Bpo.0B013E31828121B8 |
0.348 |
|
| 2013 |
Staser K, Park SJ, Rhodes SD, Zeng Y, He YZ, Shew MA, Gehlhausen JR, Cerabona D, Menon K, Chen S, Sun Z, Yuan J, Ingram DA, Nalepa G, Yang FC, et al. Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk. The Journal of Clinical Investigation. 123: 329-34. PMID 23221339 DOI: 10.1172/Jci66167 |
0.639 |
|
| 2013 |
He Y, Childress P, Hood M, Alvarez M, Kacena MA, Hanlon M, McKee B, Bidwell JP, Yang FC. Nmp4/CIZ suppresses the parathyroid hormone anabolic window by restricting mesenchymal stem cell and osteoprogenitor frequency. Stem Cells and Development. 22: 492-500. PMID 22873745 DOI: 10.1089/Scd.2012.0308 |
0.359 |
|
| 2013 |
Lin M, Pang Y, Zheng Y, Gu X, Yang F, Yuan W, Cheng T. The Supportive Role Of Mesenchymal Stem Cells On Normal Hematopoietic Stem Cells Is Impaired In Leukemic Bone Marrow Blood. 122: 1214-1214. DOI: 10.1182/Blood.V122.21.1214.1214 |
0.415 |
|
| 2012 |
He Y, Rhodes SD, Chen S, Wu X, Yuan J, Yang X, Jiang L, Li X, Takahashi N, Xu M, Mohammad KS, Guise TA, Yang FC. c-Fms signaling mediates neurofibromatosis Type-1 osteoclast gain-in-functions. Plos One. 7: e46900. PMID 23144792 DOI: 10.1371/journal.pone.0046900 |
0.652 |
|
| 2012 |
Bidwell JP, Childress P, Alvarez MB, Hood M, He Y, Pavalko FM, Kacena MA, Yang FC. Nmp4/CIZ closes the parathyroid hormone anabolic window. Critical Reviews in Eukaryotic Gene Expression. 22: 205-18. PMID 23140162 DOI: 10.1615/Critreveukargeneexpr.V22.I3.40 |
0.308 |
|
| 2012 |
Yang FC, Staser K, Clapp DW. The plexiform neurofibroma microenvironment. Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. 5: 307-10. PMID 22821631 DOI: 10.1007/s12307-012-0115-x |
0.355 |
|
| 2012 |
Staser K, Yang FC, Clapp DW. Pathogenesis of plexiform neurofibroma: tumor-stromal/hematopoietic interactions in tumor progression. Annual Review of Pathology. 7: 469-95. PMID 22077553 DOI: 10.1146/annurev-pathol-011811-132441 |
0.372 |
|
| 2012 |
Rhodes SD, He Y, Chen S, Yang H, Menon KM, Staser K, Yang X, Mohammad KS, Guise T, Xu M, Yang F. Haploinsufficiency of Nf1 in Myeloid Lineages Contributes to Neurofibromatosis Type 1 Associated Skeletal Deficits Blood. 120: 830-830. DOI: 10.1182/Blood.V120.21.830.830 |
0.707 |
|
| 2012 |
Nalepa G, Barnholtz-Sloan J, Lehmann A, Yang F, Renbarger J, Clapp D. 199 A Hybrid Genome-Kinome High-Throughput Screen Reveals Novel Mitotic Tumor Suppressor Signaling Axis Archives of Disease in Childhood. 97: A57-A58. DOI: 10.1136/Archdischild-2012-302724.0199 |
0.346 |
|
| 2011 |
Wu X, Chen S, He Y, Rhodes SD, Mohammad KS, Li X, Yang X, Jiang L, Nalepa G, Snider P, Robling AG, Clapp DW, Conway SJ, Guise TA, Yang FC. The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1. Plos One. 6: e24917. PMID 21980365 DOI: 10.1371/journal.pone.0024917 |
0.646 |
|
| 2011 |
He Y, Staser K, Rhodes SD, Liu Y, Wu X, Park SJ, Yuan J, Yang X, Li X, Jiang L, Chen S, Yang FC. Erk1 positively regulates osteoclast differentiation and bone resorptive activity. Plos One. 6: e24780. PMID 21961044 DOI: 10.1371/journal.pone.0024780 |
0.63 |
|
| 2011 |
Li Z, Cai X, Cai CL, Wang J, Zhang W, Petersen BE, Yang FC, Xu M. Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies. Blood. 118: 4509-18. PMID 21803851 DOI: 10.1182/blood-2010-12-325241 |
0.347 |
|
| 2011 |
Yang Z, Chen M, Sitarski SA, Saadatzadeh T, Yin F, Yu M, Yang FC, Chan RJ. Genetic disruption of the scaffolding protein, Kinase Suppressor of Ras 1 (KSR1), differentially regulates GM-CSF-stimulated hyperproliferation in hematopoietic progenitors expressing activating PTPN11 mutants D61Y and E76K. Leukemia Research. 35: 961-4. PMID 21555152 DOI: 10.1016/J.Leukres.2011.04.003 |
0.318 |
|
| 2011 |
Stevenson DA, Yang FC. The musculoskeletal phenotype of the RASopathies. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 157: 90-103. PMID 21495174 DOI: 10.1002/Ajmg.C.30296 |
0.391 |
|
| 2011 |
Stevenson DA, Yan J, He Y, Li H, Liu Y, Zhang Q, Jing Y, Guo Z, Zhang W, Yang D, Wu X, Hanson H, Li X, Staser K, Viskochil DH, ... ... Yang FC, et al. Multiple increased osteoclast functions in individuals with neurofibromatosis type 1. American Journal of Medical Genetics. Part A. 155: 1050-9. PMID 21465658 DOI: 10.1002/Ajmg.A.33965 |
0.415 |
|
| 2011 |
Zhang W, Rhodes SD, Zhao L, He Y, Zhang Y, Shen Y, Yang D, Wu X, Li X, Yang X, Park SJ, Chen S, Turner C, Yang FC. Primary osteopathy of vertebrae in a neurofibromatosis type 1 murine model. Bone. 48: 1378-87. PMID 21439418 DOI: 10.1016/J.Bone.2011.03.760 |
0.632 |
|
| 2011 |
Wu X, Chen S, Orlando SA, Yuan J, Kim ET, Munugalavadla V, Mali RS, Kapur R, Yang FC. p85alpha regulates osteoblast differentiation by cross-talking with the MAPK pathway. The Journal of Biological Chemistry. 286: 13512-21. PMID 21324896 DOI: 10.1074/jbc.M110.187351 |
0.369 |
|
| 2011 |
Stevenson DA, Schwarz EL, Carey JC, Viskochil DH, Hanson H, Bauer S, Weng HY, Greene T, Reinker K, Swensen J, Chan RJ, Yang FC, Senbanjo L, Yang Z, Mao R, et al. Bone resorption in syndromes of the Ras/MAPK pathway. Clinical Genetics. 80: 566-73. PMID 21204800 DOI: 10.1111/J.1399-0004.2010.01619.X |
0.418 |
|
| 2011 |
He Y, Staser K, Rhodes SD, Wu X, Zhang P, Chen S, Yang F. Erk1 Plays Critical Role in Macrophage Development Blood. 118: 517-517. DOI: 10.1182/Blood.V118.21.517.517 |
0.662 |
|
| 2011 |
Sun Z, Li J, Yang Y, Li Y, Lindemann D, Yang F, Clapp DW, Hanenberg H. Transduction of Hematopoietic Stem/Progenitor Cells with a Lentivirus Expressing FANCA off the Human Phosphoglycerate Kinase Promoter Corrects the Fanconi Anemia Phenotype, Blood. 118: 4178-4178. DOI: 10.1182/Blood.V118.21.4178.4178 |
0.44 |
|
| 2010 |
Chen S, Burgin S, McDaniel A, Li X, Yuan J, Chen M, Khalaf W, Clapp DW, Yang FC. Nf1-/- Schwann cell-conditioned medium modulates mast cell degranulation by c-Kit-mediated hyperactivation of phosphatidylinositol 3-kinase. The American Journal of Pathology. 177: 3125-32. PMID 21037083 DOI: 10.2353/ajpath.2010.100369 |
0.385 |
|
| 2010 |
Pulliam-Leath AC, Ciccone SL, Nalepa G, Li X, Si Y, Miravalle L, Smith D, Yuan J, Li J, Anur P, Orazi A, Vance GH, Yang FC, Hanenberg H, Bagby GC, et al. Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia. Blood. 116: 2915-20. PMID 20606166 DOI: 10.1182/Blood-2009-08-240747 |
0.303 |
|
| 2010 |
Staser K, Yang FC, Clapp DW. Plexiform neurofibroma genesis: questions of Nf1 gene dose and hyperactive mast cells. Current Opinion in Hematology. 17: 287-93. PMID 20571392 DOI: 10.1097/Moh.0B013E328339511B |
0.365 |
|
| 2010 |
Staser K, Yang FC, Clapp DW. Mast cells and the neurofibroma microenvironment. Blood. 116: 157-64. PMID 20233971 DOI: 10.1182/blood-2009-09-242875 |
0.436 |
|
| 2010 |
Benson EA, Goebl MG, Yang FC, Kapur R, McClintick J, Sanghani S, Clapp DW, Harrington MA. Loss of SIMPL compromises TNF-alpha-dependent survival of hematopoietic progenitors. Experimental Hematology. 38: 71-81. PMID 19941935 DOI: 10.1016/J.Exphem.2009.11.006 |
0.333 |
|
| 2009 |
Li H, Liu Y, Zhang Q, Jing Y, Chen S, Song Z, Yan J, Li Y, Wu X, Zhang X, Zhang Y, Case J, Yu M, Ingram DA, Yang FC. Ras dependent paracrine secretion of osteopontin by Nf1+/- osteoblasts promote osteoclast activation in a neurofibromatosis type I murine model. Pediatric Research. 65: 613-8. PMID 19247213 DOI: 10.1203/Pdr.0B013E3181A1C607 |
0.442 |
|
| 2009 |
Li Y, Chen S, Yuan J, Yang Y, Li J, Ma J, Wu X, Freund M, Pollok K, Hanenberg H, Goebel WS, Yang FC. Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg-/- mice in vivo. Blood. 113: 2342-51. PMID 19129541 DOI: 10.1182/Blood-2008-07-168138 |
0.455 |
|
| 2009 |
Goodman ML, Chen S, Yang FC, Chan RJ. Novel method of murine embryonic stem cell-derived osteoclast development. Stem Cells and Development. 18: 195-200. PMID 18616393 DOI: 10.1089/scd.2008.0193 |
0.326 |
|
| 2009 |
Clapp DW, Yang F, Ingram DA, Robertson KA, Hutchins GD, Parada LF. Mast Cells and Tumor Progression. Blood. 114: SCI-33-SCI-33. DOI: 10.1182/Blood.V114.22.Sci-33.Sci-33 |
0.523 |
|
| 2009 |
Li Y, Chen S, He Y, Li X, Yang F. Impaired Bone Marrow Microenvironment in Fanconi Anemia Murine Model Is Responsible for the Defective Hematopoietic Stem/ Progenitor Cell Mobilization. Blood. 114: 3629-3629. DOI: 10.1182/Blood.V114.22.3629.3629 |
0.475 |
|
| 2008 |
Yang FC, Ingram DA, Chen S, Zhu Y, Yuan J, Li X, Yang X, Knowles S, Horn W, Li Y, Zhang S, Yang Y, Vakili ST, Yu M, Burns D, et al. Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow. Cell. 135: 437-48. PMID 18984156 DOI: 10.1016/J.Cell.2008.08.041 |
0.422 |
|
| 2008 |
Yan J, Chen S, Zhang Y, Li X, Li Y, Wu X, Yuan J, Robling AG, Kapur R, Karpur R, Chan RJ, Yang FC. Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1. Human Molecular Genetics. 17: 936-48. PMID 18089636 DOI: 10.1093/Hmg/Ddm366 |
0.468 |
|
| 2007 |
Li B, Jia N, Waning DL, Yang FC, Haneline LS, Chun KT. Cul4A is required for hematopoietic stem-cell engraftment and self-renewal. Blood. 110: 2704-7. PMID 17616641 DOI: 10.1182/Blood-2006-12-064154 |
0.332 |
|
| 2007 |
Nebesio TD, Ming W, Chen S, Clegg T, Yuan J, Yang Y, Estwick SA, Li Y, Li X, Hingtgen CM, Yang FC. Neurofibromin-deficient Schwann cells have increased lysophosphatidic acid dependent survival and migration-implications for increased neurofibroma formation during pregnancy. Glia. 55: 527-36. PMID 17236191 DOI: 10.1002/glia.20482 |
0.364 |
|
| 2007 |
Chen M, Horn W, Li X, Knowles S, Ingram D, Chen S, Yang F, Clapp DW. Kinase Suppressor of Ras Plays a Critical Role in Modulating Inflammatory Mast Cell Functions. Blood. 110: 2407-2407. DOI: 10.1182/Blood.V110.11.2407.2407 |
0.398 |
|
| 2007 |
Yang F, Ingram D, Chen S, Robertson K, Li X, Yuan J, Knoll S, Horn W, Hutchins G, Parada L, Clapp DW. Imatinib Mesylate Reduces Plexiform Neurofibromas by Targeting the Hematopoietic Microenvironment. Blood. 110: 1915-1915. DOI: 10.1182/Blood.V110.11.1915.1915 |
0.392 |
|
| 2006 |
Yang FC, Chen S, Robling AG, Yu X, Nebesio TD, Yan J, Morgan T, Li X, Yuan J, Hock J, Ingram DA, Clapp DW. Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions. The Journal of Clinical Investigation. 116: 2880-91. PMID 17053831 DOI: 10.1172/JCI29092 |
0.468 |
|
| 2006 |
Wu X, Estwick SA, Chen S, Yu M, Ming W, Nebesio TD, Li Y, Yuan J, Kapur R, Ingram D, Yoder MC, Yang FC. Neurofibromin plays a critical role in modulating osteoblast differentiation of mesenchymal stem/progenitor cells. Human Molecular Genetics. 15: 2837-45. PMID 16893911 DOI: 10.1093/Hmg/Ddl208 |
0.445 |
|
| 2006 |
Yang FC, Chen S, Clegg T, Li X, Morgan T, Estwick SA, Yuan J, Khalaf W, Burgin S, Travers J, Parada LF, Ingram DA, Clapp DW. Nf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signaling. Human Molecular Genetics. 15: 2421-37. PMID 16835260 DOI: 10.1093/hmg/ddl165 |
0.309 |
|
| 2006 |
Munchhof AM, Li F, White HA, Mead LE, Krier TR, Fenoglio A, Li X, Yuan J, Yang FC, Ingram DA. Neurofibroma-associated growth factors activate a distinct signaling network to alter the function of neurofibromin-deficient endothelial cells. Human Molecular Genetics. 15: 1858-69. PMID 16648142 DOI: 10.1093/hmg/ddl108 |
0.402 |
|
| 2006 |
Yang F, Ingram DA, Chen S, Yuan J, Li X, Horn W, Parada L, Clapp DW. Mast Cells Are Integral Components of the Tumor Microenvironment That Are Required for Plexiform Neurofibroma Progression. Blood. 108: 677-677. DOI: 10.1182/Blood.V108.11.677.677 |
0.528 |
|
| 2006 |
Chen S, Robling A, Li X, Yuan J, Hock J, Ingram DA, Clapp DW, Yang F. Hyperactivation of p21ras and PI3-K Cooperate To Alter Murine and Human NF1 Haploinsufficient Osteoclast Functions. Blood. 108: 675-675. DOI: 10.1182/Blood.V108.11.675.675 |
0.548 |
|
| 2006 |
Pulliam AC, Hobson MJ, Yang F, Broxmeyer HE, Clapp DW. AMD3100 and G-CSF Synergize To Promote Repopulating Stem Cell Mobilization in Fanca −/− and Fancc −/− Mice. Blood. 108: 3760-3760. DOI: 10.1182/Blood.V108.11.3760.3760 |
0.395 |
|
| 2006 |
Yang F, Allen J, Chen S, Li Y, Yuan J, Bessler W, Ingram DA, Clapp DW. Genetic Disruption of Rac1 but Not Rac2 Is Sufficient To Ameliorate the Development of Juvenile Myeloproliferative Myeloid Leukemia in Nf1−/− Mice. Blood. 108: 3612-3612. DOI: 10.1182/Blood.V108.11.3612.3612 |
0.488 |
|
| 2005 |
Jansen M, Yang FC, Cancelas JA, Bailey JR, Williams DA. Rac2-deficient hematopoietic stem cells show defective interaction with the hematopoietic microenvironment and long-term engraftment failure. Stem Cells (Dayton, Ohio). 23: 335-46. PMID 15749928 DOI: 10.1634/stemcells.2004-0216 |
0.326 |
|
| 2005 |
Li X, Le Beau MM, Ciccone S, Yang FC, Freie B, Chen S, Yuan J, Hong P, Orazi A, Haneline LS, Clapp DW. Ex vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy. Blood. 105: 3465-71. PMID 15644418 DOI: 10.1182/Blood-2004-06-2483 |
0.311 |
|
| 2005 |
Munchhof AM, Li F, Mead L, White H, Fenoglio A, Yang F, Ingram DA. Function of the NF1 Tumor Suppressor Gene in Angiogenesis. Blood. 106: 3680-3680. DOI: 10.1182/Blood.V106.11.3680.3680 |
0.462 |
|
| 2005 |
Yang F. Adoptive Transfer of Nf1+/− Bone Marrow Is Sufficient for Neurofibroma Progression in Krox20;Nf1flox/flox Mice. Blood. 106: 3064-3064. DOI: 10.1182/Blood.V106.11.3064.3064 |
0.553 |
|
| 2004 |
Khalaf WF, Hardesty DA, Chen S, Yang F, White H, Wenning MJ, Ingram DA, Clapp DW. The Role of Neurofibromin as a GTPase Activating Protein for K-ras in Mast Cells. Blood. 104: 2560-2560. DOI: 10.1182/Blood.V104.11.2560.2560 |
0.391 |
|
| 2004 |
Yang F, Travis C, Chen S, Li X, Estwick SA, Yuan J, Ingram DA, Clapp DW. Murine and Human NF1 Haploinsufficient Mast Cells Promote Alterations in Fibroblast Function and Organization of the Extracellular Matrix in Three-Dimensional Collagen Lattices and this Gain in Function Is Abrogated by the Addition of STI-571. Blood. 104: 1465-1465. DOI: 10.1182/blood.v104.11.1465.1465 |
0.353 |
|
| 2004 |
Chen S, Ingram DA, Wenning MJ, Hock J, Yang F, Clapp DW. Nf1 Plays an Essential Role in Osteoclasts Development Via Hyperactivation of Ras- PI3K Signaling. Blood. 104: 1462-1462. DOI: 10.1182/Blood.V104.11.1462.1462 |
0.543 |
|
| 2003 |
Yang FC, Ingram DA, Chen S, Hingtgen CM, Ratner N, Monk KR, Clegg T, White H, Mead L, Wenning MJ, Williams DA, Kapur R, Atkinson SJ, Clapp DW. Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells. The Journal of Clinical Investigation. 112: 1851-61. PMID 14679180 DOI: 10.1172/Jci19195 |
0.406 |
|
| 2001 |
Yang FC, Atkinson SJ, Gu Y, Borneo JB, Roberts AW, Zheng Y, Pennington J, Williams DA. Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization Proceedings of the National Academy of Sciences of the United States of America. 98: 5614-5618. PMID 11320224 DOI: 10.1073/Pnas.101546898 |
0.411 |
|
| 2000 |
Ingram DA, Yang FC, Travers JB, Wenning MJ, Hiatt K, New S, Hood A, Shannon K, Williams DA, Clapp DW. Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo Journal of Experimental Medicine. 191: 181-187. PMID 10620616 DOI: 10.1084/Jem.191.1.181 |
0.438 |
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