| Year |
Citation |
Score |
| 2019 |
Dutta NK, Klinkenberg LG, Vazquez MJ, Segura-Carro D, Colmenarejo G, Ramon F, Rodriguez-Miquel B, Mata-Cantero L, Porras-De Francisco E, Chuang YM, Rubin H, Lee JJ, Eoh H, Bader JS, Perez-Herran E, et al. Inhibiting the stringent response blocks entry into quiescence and reduces persistence. Science Advances. 5: eaav2104. PMID 30906866 DOI: 10.1126/Sciadv.Aav2104 |
0.378 |
|
| 2018 |
Harbut MB, Liu R, Yang B, Yano T, Vilcheze C, Lockner J, Guo H, Franzblau SG, Petrassi M, Jacobs WR, Rubin H, Chatterjee AK, Wang F. Small molecules targeting Mycobacterium tuberculosis type II NADH dehydrogenase with antimycobacterial activity. Angewandte Chemie (International Ed. in English). PMID 29388301 DOI: 10.1002/Anie.201800260 |
0.414 |
|
| 2017 |
Tantry SJ, Markad SD, Shinde V, Bhat J, Balakrishnan G, Gupta AK, Ambady A, Raichurkar AV, Kedari C, Sharma S, Mudugal NV, Narayan A, Naveen Kumar CN, Nanduri R, Bharath S, ... ... Rubin H, et al. Discovery of Imidazo[1,2-a]pyridine ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis. Journal of Medicinal Chemistry. PMID 28075132 DOI: 10.1021/Acs.Jmedchem.6B01358 |
0.39 |
|
| 2016 |
Chuang YM, Dutta NK, Hung CF, Wu TC, Rubin H, Karakousis PC. The stringent response factors PPX1 and PPK2 play an important role in Mycobacterium tuberculosis metabolism, biofilm formation, and sensitivity to isoniazid in vivo. Antimicrobial Agents and Chemotherapy. PMID 27527086 DOI: 10.1128/Aac.01139-16 |
0.407 |
|
| 2016 |
Tantry SJ, Shinde V, Balakrishnan G, Markad SD, Gupta AK, Bhat J, Narayan A, Raichurkar A, Jena LK, Sharma S, Kumar N, Nanduri R, Bharath S, Reddy J, Panduga V, ... ... Rubin H, et al. Scaffold morphing leading to evolution of 2,4-diaminoquinolines and aminopyrazolopyrimidines as inhibitors of the ATP synthesis pathway Medchemcomm. 7: 1022-1032. DOI: 10.1039/C5Md00589B |
0.372 |
|
| 2015 |
Chuang YM, Bandyopadhyay N, Rifat D, Rubin H, Bader JS, Karakousis PC. Deficiency of the novel exopolyphosphatase Rv1026/PPX2 leads to metabolic downshift and altered cell wall permeability in Mycobacterium tuberculosis. Mbio. 6: e02428. PMID 25784702 DOI: 10.1128/Mbio.02428-14 |
0.444 |
|
| 2015 |
Rubin H, Selwood T, Yano T, Weaver DG, Loughran HM, Costanzo MJ, Scott RW, Wrobel JE, Freeman KB, Reitz AB. Acinetobacter baumannii OxPhos inhibitors as selective anti-infective agents. Bioorganic & Medicinal Chemistry Letters. 25: 378-83. PMID 25496770 DOI: 10.1016/J.Bmcl.2014.11.020 |
0.33 |
|
| 2014 |
Schurig-Briccio LA, Yano T, Rubin H, Gennis RB. Characterization of the type 2 NADH:menaquinone oxidoreductases from Staphylococcus aureus and the bactericidal action of phenothiazines. Biochimica Et Biophysica Acta. 1837: 954-63. PMID 24709059 DOI: 10.1016/J.Bbabio.2014.03.017 |
0.352 |
|
| 2014 |
Yano T, Rahimian M, Aneja KK, Schechter NM, Rubin H, Scott CP. Mycobacterium tuberculosis type II NADH-menaquinone oxidoreductase catalyzes electron transfer through a two-site ping-pong mechanism and has two quinone-binding sites. Biochemistry. 53: 1179-90. PMID 24447297 DOI: 10.1021/Bi4013897 |
0.329 |
|
| 2011 |
Thayil SM, Morrison N, Schechter N, Rubin H, Karakousis PC. The role of the novel exopolyphosphatase MT0516 in Mycobacterium tuberculosis drug tolerance and persistence. Plos One. 6: e28076. PMID 22132215 DOI: 10.1371/Journal.Pone.0028076 |
0.44 |
|
| 2008 |
Buckstein MH, He J, Rubin H. Characterization of nucleotide pools as a function of physiological state in Escherichia coli. Journal of Bacteriology. 190: 718-26. PMID 17965154 DOI: 10.1128/Jb.01020-07 |
0.628 |
|
| 2006 |
Zhu L, Zhang Y, Teh JS, Zhang J, Connell N, Rubin H, Inouye M. Characterization of mRNA interferases from Mycobacterium tuberculosis. The Journal of Biological Chemistry. 281: 18638-43. PMID 16611633 DOI: 10.1074/Jbc.M512693200 |
0.36 |
|
| 2006 |
Yano T, Li LS, Weinstein E, Teh JS, Rubin H. Steady-state kinetics and inhibitory action of antitubercular phenothiazines on mycobacterium tuberculosis type-II NADH-menaquinone oxidoreductase (NDH-2). The Journal of Biological Chemistry. 281: 11456-63. PMID 16469750 DOI: 10.1074/Jbc.M508844200 |
0.387 |
|
| 2006 |
Imielinski M, Belta C, Rubin H, Halász A. Systematic analysis of conservation relations in Escherichia coli genome-scale metabolic network reveals novel growth media. Biophysical Journal. 90: 2659-72. PMID 16461408 DOI: 10.1529/Biophysj.105.069278 |
0.576 |
|
| 2005 |
Matsoso LG, Kana BD, Crellin PK, Lea-Smith DJ, Pelosi A, Powell D, Dawes SS, Rubin H, Coppel RL, Mizrahi V. Function of the cytochrome bc1-aa3 branch of the respiratory network in mycobacteria and network adaptation occurring in response to its disruption. Journal of Bacteriology. 187: 6300-8. PMID 16159762 DOI: 10.1128/Jb.187.18.6300-6308.2005 |
0.397 |
|
| 2005 |
Avarbock A, Avarbock D, Teh JS, Buckstein M, Wang ZM, Rubin H. Functional regulation of the opposing (p)ppGpp synthetase/hydrolase activities of RelMtb from Mycobacterium tuberculosis. Biochemistry. 44: 9913-23. PMID 16026164 DOI: 10.1021/Bi0505316 |
0.704 |
|
| 2005 |
Weinstein EA, Yano T, Li LS, Avarbock D, Avarbock A, Helm D, McColm AA, Duncan K, Lonsdale JT, Rubin H. Inhibitors of type II NADH:menaquinone oxidoreductase represent a class of antitubercular drugs. Proceedings of the National Academy of Sciences of the United States of America. 102: 4548-53. PMID 15767566 DOI: 10.1073/Pnas.0500469102 |
0.718 |
|
| 2004 |
Uppsten M, Davis J, Rubin H, Uhlin U. Crystal structure of the biologically active form of class Ib ribonucleotide reductase small subunit from Mycobacterium tuberculosis. Febs Letters. 569: 117-22. PMID 15225619 DOI: 10.1016/J.Febslet.2004.05.059 |
0.583 |
|
| 2003 |
Dawes SS, Warner DF, Tsenova L, Timm J, McKinney JD, Kaplan G, Rubin H, Mizrahi V. Ribonucleotide reduction in Mycobacterium tuberculosis: function and expression of genes encoding class Ib and class II ribonucleotide reductases. Infection and Immunity. 71: 6124-31. PMID 14573627 DOI: 10.1128/Iai.71.11.6124-6131.2003 |
0.433 |
|
| 2003 |
Dahl JL, Kraus CN, Boshoff HI, Doan B, Foley K, Avarbock D, Kaplan G, Mizrahi V, Rubin H, Barry CE. The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 10026-31. PMID 12897239 DOI: 10.1073/Pnas.1631248100 |
0.757 |
|
| 2002 |
Plotnick MI, Rubin H, Schechter NM. The effects of reactive site location on the inhibitory properties of the serpin alpha(1)-antichymotrypsin. The Journal of Biological Chemistry. 277: 29927-35. PMID 12055188 DOI: 10.1074/Jbc.M202374200 |
0.332 |
|
| 2002 |
Que X, Brinen LS, Perkins P, Herdman S, Hirata K, Torian BE, Rubin H, McKerrow JH, Reed SL. Cysteine proteinases from distinct cellular compartments are recruited to phagocytic vesicles by Entamoeba histolytica. Molecular and Biochemical Parasitology. 119: 23-32. PMID 11755183 DOI: 10.1016/S0166-6851(01)00387-5 |
0.365 |
|
| 2001 |
Kana BD, Weinstein EA, Avarbock D, Dawes SS, Rubin H, Mizrahi V. Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis. Journal of Bacteriology. 183: 7076-86. PMID 11717265 DOI: 10.1128/Jb.183.24.7076-7086.2001 |
0.765 |
|
| 2000 |
Avarbock D, Avarbock A, Rubin H. Differential regulation of opposing RelMtb activities by the aminoacylation state of a tRNA.ribosome.mRNA.RelMtb complex. Biochemistry. 39: 11640-8. PMID 10995231 DOI: 10.1021/Bi001256K |
0.768 |
|
| 2000 |
Primm TP, Andersen SJ, Mizrahi V, Avarbock D, Rubin H, Barry CE. The stringent response of Mycobacterium tuberculosis is required for long-term survival. Journal of Bacteriology. 182: 4889-98. PMID 10940033 DOI: 10.1128/Jb.182.17.4889-4898.2000 |
0.773 |
|
| 1999 |
Avarbock D, Salem J, Li LS, Wang ZM, Rubin H. Cloning and characterization of a bifunctional RelA/SpoT homologue from Mycobacterium tuberculosis. Gene. 233: 261-9. PMID 10375643 DOI: 10.1016/S0378-1119(99)00114-6 |
0.775 |
|
| 1999 |
Pereira PJ, Wang ZM, Rubin H, Huber R, Bode W, Schechter NM, Strobl S. The 2.2 A Crystal Structure of Human Chymase in Complex with Succinyl-Ala-Ala-Pro-Phe-chloromethylketone: Structural Explanation for its Dipeptidyl Carboxypeptidase Specificity. Journal of Molecular Biology. 286: 817. PMID 10208809 DOI: 10.1006/Jmbi.1999.2691 |
0.321 |
|
| 1999 |
Avarbock D, Salem J, Li L, Wang Z, Rubin H. Erratum to: “Cloning and characterization of a bifunctional RelA/SpoT homologue from Mycobacterium tuberculosis” Gene. 239: 205. DOI: 10.1016/S0378-1119(99)00417-5 |
0.761 |
|
| 1998 |
Elleingand E, Gerez C, Un S, Knüpling M, Lu G, Salem J, Rubin H, Sauge-Merle S, Laulhère JP, Fontecave M. Reactivity studies of the tyrosyl radical in ribonucleotide reductase from Mycobacterium tuberculosis and Arabidopsis thaliana comparison with Escherichia coli and mouse European Journal of Biochemistry. 258: 485-490. PMID 9874215 DOI: 10.1046/J.1432-1327.1998.2580485.X |
0.357 |
|
| 1998 |
Wang Z, Walter M, Selwood T, Rubin H, Schechter NM. Recombinant expression of human mast cell proteases chymase and tryptase. Biological Chemistry. 379: 167-174. PMID 9524068 DOI: 10.1515/Bchm.1998.379.2.167 |
0.329 |
|
| 1998 |
Lukacs CM, Rubin H, Christianson DW. Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. Biochemistry. 37: 3297-304. PMID 9521649 DOI: 10.1021/Bi972359E |
0.323 |
|
| 1997 |
Plotnick MI, Schechter NM, Wang ZM, Liu X, Rubin H. Role of the P6-P3' region of the serpin reactive loop in the formation and breakdown of the inhibitory complex. Biochemistry. 36: 14601-14608. PMID 9398179 DOI: 10.1021/Bi971530J |
0.353 |
|
| 1997 |
Yang F, Curran SC, Li LS, Avarbock D, Graf JD, Chua MM, Lu G, Salem J, Rubin H. Characterization of two genes encoding the Mycobacterium tuberculosis ribonucleotide reductase small subunit. Journal of Bacteriology. 179: 6408-15. PMID 9335290 DOI: 10.1128/Jb.179.20.6408-6415.1997 |
0.771 |
|
| 1997 |
Ware JH, Wan XS, Rubin H, Schechter NM, Kennedy AR. Soybean Bowman-Birk protease inhibitor is a highly effective inhibitor of human mast cell chymase. Archives of Biochemistry and Biophysics. 344: 133-8. PMID 9244390 DOI: 10.1006/Abbi.1997.0182 |
0.31 |
|
| 1997 |
O'Malley KM, Nair SA, Rubin H, Cooperman BS. The kinetic mechanism of serpin-proteinase complex formation. An intermediate between the michaelis complex and the inhibited complex. The Journal of Biological Chemistry. 272: 5354-9. PMID 9030611 DOI: 10.1074/Jbc.272.8.5354 |
0.311 |
|
| 1996 |
Yang F, Lu G, Rubin H. Cloning, expression, purification and characterization of DNA topoisomerase I of Mycobacterium tuberculosis. Gene. 178: 63-9. PMID 8921893 DOI: 10.1016/0378-1119(96)00335-6 |
0.406 |
|
| 1996 |
Stavridi ES, O'Malley K, Lukacs CM, Moore WT, Lambris JD, Christianson DW, Rubin H, Cooperman BS. Structural change in alpha-chymotrypsin induced by complexation with alpha 1-antichymotrypsin as seen by enhanced sensitivity to proteolysis. Biochemistry. 35: 10608-15. PMID 8718849 DOI: 10.1021/Bi9605806 |
0.315 |
|
| 1996 |
Plotnick MI, Mayne L, Schechter NM, Rubin H. Distortion of the Active Site of Chymotrypsin Complexed with a Serpin Biochemistry. 35: 7586-7590. PMID 8652540 DOI: 10.1021/Bi960233W |
0.329 |
|
| 1994 |
Rubin H. Conversion of α1-antichymotrypsin into a human neutrophil elastase inhibitor: Demonstration of variants with different association rate constants, stoichiometries of inhibition, and complex stabilities Biochemistry. 33: 7627-7633. PMID 8011628 DOI: 10.1021/Bi00190A016 |
0.382 |
|
| 1994 |
Yang F, Lu G, Rubin H. Isolation of ribonucleotide reductase from Mycobacterium tuberculosis and cloning, expression, and purification of the large subunit. Journal of Bacteriology. 176: 6738-43. PMID 7961427 DOI: 10.1128/Jb.176.21.6738-6743.1994 |
0.4 |
|
| 1994 |
Henriksen MA, Cooperman BS, Salem JS, Li L, Rubin H. The Stable Tyrosyl Radical in Mouse Ribonucleotide Reductase Is Not Essential for Enzymic Activity Journal of the American Chemical Society. 116: 9773-9774. DOI: 10.1021/Ja00100A062 |
0.303 |
|
| 1993 |
Salem JS, Scott CP, Li LS, Cooperman BS, Rubin H. High level expression of the large subunit of mouse ribonucleotide reductase in a baculovirus system Febs Letters. 323: 93-95. PMID 8495754 DOI: 10.1016/0014-5793(93)81455-9 |
0.325 |
|
| 1993 |
Rubin H, Salem JS, Li LS, Yang FD, Mama S, Wang ZM, Fisher A, Hamann CS, Cooperman BS. Cloning, sequence determination, and regulation of the ribonucleotide reductase subunits from Plasmodium falciparum: a target for antimalarial therapy. Proceedings of the National Academy of Sciences of the United States of America. 90: 9280-4. PMID 8415692 DOI: 10.1073/Pnas.90.20.9280 |
0.363 |
|
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