| Year |
Citation |
Score |
| 2020 |
Stachel SJ, Ginnetti AT, Johnson SA, Cramer P, Wang Y, Bukhtiyarova M, Krosky D, Stump C, Hurzy DM, Schlegel KA, Cooke AJ, Allen S, O'Donnell G, Ziebell M, Parthasarathy G, ... ... Lumb K, et al. Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorganic & Medicinal Chemistry Letters. 30: 127403. PMID 32738972 DOI: 10.1016/J.Bmcl.2020.127403 |
0.445 |
|
| 2020 |
Allen SJ, Lumb KJ. Protein-protein interactions: a structural view of inhibition strategies and the IL-23/IL-17 axis. Advances in Protein Chemistry and Structural Biology. 121: 253-303. PMID 32312425 DOI: 10.1016/Bs.Apcsb.2019.12.006 |
0.404 |
|
| 2017 |
Lu J, Byrne N, Wang J, Bricogne G, Brown FK, Chobanian HR, Colletti SL, Di Salvo J, Thomas-Fowlkes B, Guo Y, Hall DL, Hadix J, Hastings NB, Hermes JD, Ho T, ... ... Lumb KJ, et al. Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40. Nature Structural & Molecular Biology. PMID 28581512 DOI: 10.1038/Nsmb.3417 |
0.473 |
|
| 2017 |
Elsen NL, Patel SB, Ford RE, Hall DL, Hess F, Kandula H, Kornienko M, Reid J, Selnick H, Shipman JM, Sharma S, Lumb KJ, Soisson SM, Klein DJ. Insights into activity and inhibition from the crystal structure of human O-GlcNAcase. Nature Chemical Biology. PMID 28346407 DOI: 10.1038/Nchembio.2357 |
0.482 |
|
| 2017 |
Blevitt JM, Hack MD, Herman KL, Jackson PF, Krawczuk PJ, Lebsack AD, Liu AX, Mirzadegan T, Nelen MI, Patrick AN, Steinbacher S, Milla ME, Lumb KJ. Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein-Protein Interaction. Journal of Medicinal Chemistry. PMID 28300404 DOI: 10.1021/Acs.Jmedchem.6B01836 |
0.439 |
|
| 2016 |
Su HP, Rickert K, Burlein C, Narayan K, Bukhtiyarova M, Hurzy DM, Stump CA, Zhang X, Reid J, Krasowska-Zoladek A, Tummala S, Shipman JM, Kornienko M, Lemaire PA, Krosky D, ... ... Lumb KJ, et al. Structural characterization of nonactive site, TrkA-selective kinase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. PMID 28039433 DOI: 10.1073/Pnas.1611577114 |
0.468 |
|
| 2015 |
Allen SJ, Parthasarathy G, Darke PL, Diehl RE, Ford RE, Hall DL, Johnson SA, Reid JC, Rickert KW, Shipman JM, Soisson SM, Zuck P, Munshi SK, Lumb KJ. Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4. The Journal of Biological Chemistry. PMID 26134571 DOI: 10.1074/Jbc.M115.648907 |
0.469 |
|
| 2014 |
Lu J, Patel S, Sharma N, Soisson SM, Kishii R, Takei M, Fukuda Y, Lumb KJ, Singh SB. Structures of kibdelomycin bound to Staphylococcus aureus GyrB and ParE showed a novel U-shaped binding mode. Acs Chemical Biology. 9: 2023-31. PMID 24992706 DOI: 10.1021/Cb5001197 |
0.459 |
|
| 2012 |
Elsen NL, Lu J, Parthasarathy G, Reid JC, Sharma S, Soisson SM, Lumb KJ. Mechanism of action of the cell-division inhibitor PC190723: modulation of FtsZ assembly cooperativity. Journal of the American Chemical Society. 134: 12342-5. PMID 22793495 DOI: 10.1021/Ja303564A |
0.481 |
|
| 2011 |
Rickert KW, Patel SB, Allison TJ, Byrne NJ, Darke PL, Ford RE, Guerin DJ, Hall DL, Kornienko M, Lu J, Munshi SK, Reid JC, Shipman JM, Stanton EF, Wilson KJ, ... ... Lumb KJ, et al. Structural basis for selective small molecule kinase inhibition of activated c-Met. The Journal of Biological Chemistry. 286: 11218-25. PMID 21247903 DOI: 10.1074/Jbc.M110.204404 |
0.497 |
|
| 2010 |
Sunami T, Byrne N, Diehl RE, Funabashi K, Hall DL, Ikuta M, Patel SB, Shipman JM, Smith RF, Takahashi I, Zugay-Murphy J, Iwasawa Y, Lumb KJ, Munshi SK, Sharma S. Structural basis of human p70 ribosomal S6 kinase-1 regulation by activation loop phosphorylation. The Journal of Biological Chemistry. 285: 4587-94. PMID 19864428 DOI: 10.1074/Jbc.M109.040667 |
0.391 |
|
| 2005 |
Salhanick AI, Clairmont KB, Buckholz TM, Pellegrino CM, Ha S, Lumb KJ. Contribution of site-specific PEGylation to the dipeptidyl peptidase IV stability of glucose-dependent insulinotropic polypeptide. Bioorganic & Medicinal Chemistry Letters. 15: 4114-7. PMID 15993590 DOI: 10.1016/J.Bmcl.2005.06.002 |
0.352 |
|
| 2005 |
Horng JC, Tracz SM, Lumb KJ, Raleigh DP. Slow folding of a three-helix protein via a compact intermediate. Biochemistry. 44: 627-34. PMID 15641788 DOI: 10.1021/Bi048852P |
0.563 |
|
| 2004 |
Vendel AC, Lumb KJ. NMR mapping of the HIV-1 Tat interaction surface of the KIX domain of the human coactivator CBP. Biochemistry. 43: 904-8. PMID 14744133 DOI: 10.1021/Bi035612L |
0.754 |
|
| 2003 |
Vendel AC, McBryant SJ, Lumb KJ. KIX-mediated assembly of the CBP-CREB-HTLV-1 tax coactivator-activator complex. Biochemistry. 42: 12481-7. PMID 14580193 DOI: 10.1021/Bi0353023 |
0.773 |
|
| 2003 |
Wei Y, Horng JC, Vendel AC, Raleigh DP, Lumb KJ. Contribution to stability and folding of a buried polar residue at the CARM1 methylation site of the KIX domain of CBP. Biochemistry. 42: 7044-9. PMID 12795599 DOI: 10.1021/Bi0343976 |
0.751 |
|
| 2003 |
Vendel AC, Lumb KJ. Molecular recognition of the human coactivator CBP by the HIV-1 transcriptional activator Tat. Biochemistry. 42: 910-6. PMID 12549909 DOI: 10.1021/Bi0270034 |
0.759 |
|
| 2002 |
Campbell KM, Lumb KJ. Structurally distinct modes of recognition of the KIX domain of CBP by Jun and CREB. Biochemistry. 41: 13956-64. PMID 12437352 DOI: 10.1021/Bi026222M |
0.724 |
|
| 2002 |
Campbell KM, Lumb KJ. Complementation of buried lysine and surface polar residues in a designed heterodimeric coiled coil. Biochemistry. 41: 7169-75. PMID 12033951 DOI: 10.1021/Bi025559L |
0.692 |
|
| 2002 |
Campbell KM, Sholders AJ, Lumb KJ. Contribution of buried lysine residues to the oligomerization specificity and stability of the fos coiled coil. Biochemistry. 41: 4866-71. PMID 11939781 DOI: 10.1021/Bi0159276 |
0.683 |
|
| 2002 |
Bienkiewicz EA, Adkins JN, Lumb KJ. Functional consequences of preorganized helical structure in the intrinsically disordered cell-cycle inhibitor p27(Kip1). Biochemistry. 41: 752-9. PMID 11790096 DOI: 10.1021/Bi015763T |
0.644 |
|
| 2002 |
Adkins JN, Lumb KJ. Intrinsic structural disorder and sequence features of the cell cycle inhibitor p57Kip2. Proteins. 46: 1-7. PMID 11746698 DOI: 10.1002/Prot.10018 |
0.625 |
|
| 2001 |
Stargell LA, Ogg RC, Adkins JN, Robinson MM, Lumb KJ. Transcriptional activity of the TFIIA four-helix bundle in vivo. Proteins. 43: 227-32. PMID 11276091 DOI: 10.1002/1097-0134(20010501)43:2<227::Aid-Prot1033>3.0.Co;2-C |
0.635 |
|
| 2000 |
Adkins JN, Lumb KJ. Stoichiometry of cyclin A-cyclin-dependent kinase 2 inhibition by p21Cip1/Waf1. Biochemistry. 39: 13925-30. PMID 11076534 DOI: 10.1021/Bi001524E |
0.564 |
|
| 2000 |
Campbell KM, Terrell AR, Laybourn PJ, Lumb KJ. Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor Fos. Biochemistry. 39: 2708-13. PMID 10704222 DOI: 10.1021/Bi9923555 |
0.426 |
|
| 2000 |
Campbell KM, Ranallo RT, Stargell LA, Lumb KJ. Reevaluation of transcriptional regulation by TATA-binding protein oligomerization: predominance of monomers. Biochemistry. 39: 2633-8. PMID 10704213 DOI: 10.1021/Bi9922998 |
0.458 |
|
| 1999 |
Bienkiewicz EA, Lumb KJ. Random-coil chemical shifts of phosphorylated amino acids Journal of Biomolecular Nmr. 15: 203-206. PMID 10677823 DOI: 10.1023/A:1008375029746 |
0.357 |
|
| 1999 |
Mestas SP, Lumb KJ. Electrostatic contribution of phosphorylation to the stability of the CREB-CBP activator-coactivator complex Nature Structural Biology. 6: 613-614. PMID 10404213 DOI: 10.1038/10655 |
0.308 |
|
| 1996 |
Lumb KJ, Kim PS. Response: how much solar radiation do clouds absorb? Science (New York, N.Y.). 271: 1137-8. PMID 17792302 DOI: 10.1126/Science.271.5252.1137 |
0.369 |
|
| 1996 |
Laigne P, Sonnichsen FD, Kay CM, Hodges RS, Lumb KJ, Kim PS. Interhelical salt bridges, coiled-coil stability, and specificity of dimerization Science. 271: 1136-1138. PMID 8599093 DOI: 10.1126/Science.271.5252.1136 |
0.428 |
|
| 1995 |
Lumb KJ, Kim PS. Measurement of interhelical electrostatic interactions in the GCN4 leucine zipper Science. 268: 436-439. PMID 7716550 DOI: 10.1126/Science.7716550 |
0.558 |
|
| 1995 |
Lumb KJ. A buried polar interaction imparts structural uniqueness in a designed heterodimeric coiled coil Biochemistry®. 34: 8642-8648. PMID 7612604 DOI: 10.1021/Bi00027A013 |
0.436 |
|
| 1995 |
Davidson AR, Lumb KJ, Sauer RT. Cooperatively folded proteins in random sequence libraries Nature Structural Biology. 2: 856-864. PMID 7552709 DOI: 10.1038/Nsb1095-856 |
0.349 |
|
| 1994 |
Lumb KJ, Cheetham JC, Dobson CM. 1H nuclear magnetic resonance studies of hen lysozyme-N-acetylglucosamine oligosaccharide complexes in solution. Application of chemical shifts for the comparison of conformational changes in solution and in the crystal. Journal of Molecular Biology. 235: 1072-87. PMID 8289309 DOI: 10.1006/Jmbi.1994.1058 |
0.492 |
|
| 1994 |
Lumb KJ, Carr CM, Kim PS. Subdomain folding of the coiled coil leucine zipper from the bZIP transcriptional activator GCN4 Biochemistry. 33: 7361-7367. PMID 8003501 DOI: 10.1021/Bi00189A042 |
0.572 |
|
| 1994 |
Lumb KJ, Kim PS. Formation of a hydrophobic cluster in denatured bovine pancreatic trypsin inhibitor Journal of Molecular Biology. 236: 412-420. PMID 7508987 DOI: 10.1006/Jmbi.1994.1153 |
0.528 |
|
| 1993 |
O'Shea EK, Lumb KJ, Kim PS. Peptide 'Velcro': design of a heterodimeric coiled coil. Current Biology : Cb. 3: 658-67. PMID 15335856 DOI: 10.1016/0960-9822(93)90063-T |
0.672 |
|
| 1992 |
Lumb KJ, Aplin RT, Radford SE, Archer DB, Jeenes DJ, Lambert N, MacKenzie DA, Dobson CM, Lowe G. A study of D52S hen lysozyme-GlcNAc oligosaccharide complexes by NMR spectroscopy and electrospray mass spectrometry. Febs Letters. 296: 153-7. PMID 1733771 DOI: 10.1016/0014-5793(92)80368-Q |
0.466 |
|
| 1992 |
Lumb KJ, Dobson CM. 1H nuclear magnetic resonance studies of the interaction of urea with hen lysozyme. Origins of the conformational change induced in hen lysozyme by N-acetylglucosamine oligosaccharides Journal of Molecular Biology. 227: 9-14. PMID 1522604 DOI: 10.1016/0022-2836(92)90677-C |
0.528 |
|
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