| Year |
Citation |
Score |
| 2022 |
Gihaz S, Gareiss P, Choi JY, Renard I, Pal AC, Surovsteva Y, Chiu JE, Thekkiniath J, Plummer M, Hungerford W, Montgomery ML, Hosford A, Adams EM, Lightfoot JD, Fox D, ... ... Staker BL, et al. High-resolution crystal structure and chemical screening reveal pantothenate kinase as a new target for antifungal development. Structure (London, England : 1993). PMID 36167065 DOI: 10.1016/j.str.2022.09.001 |
0.353 |
|
| 2022 |
Maddy J, Staker BL, Subramanian S, Abendroth J, Edwards TE, Myler PJ, Hybiske K, Asojo OA. Crystal structure of an inorganic pyrophosphatase from Chlamydia trachomatis D/UW-3/Cx. Acta Crystallographica. Section F, Structural Biology Communications. 78: 135-142. PMID 35234139 DOI: 10.1107/S2053230X22002138 |
0.332 |
|
| 2022 |
Beard DK, Bristol S, Cosby K, Davis A, Manning C, Perry L, Snapp L, Toy A, Wheeler K, Young J, Staker B, Arakaki TL, Abendroth J, Subrahamanian S, Edwards TE, et al. Crystal structure of a hypothetical protein from Giardia lamblia. Acta Crystallographica. Section F, Structural Biology Communications. 78: 59-65. PMID 35102894 DOI: 10.1107/S2053230X21013595 |
0.366 |
|
| 2022 |
Porter I, Neal T, Walker Z, Hayes D, Fowler K, Billups N, Rhoades A, Smith C, Smith K, Staker BL, Dranow DM, Mayclin SJ, Subramanian S, Edwards TE, Myler PJ, et al. Crystal structures of FolM alternative dihydrofolate reductase 1 from Brucella suis and Brucella canis. Acta Crystallographica. Section F, Structural Biology Communications. 78: 31-38. PMID 34981773 DOI: 10.1107/S2053230X21013078 |
0.357 |
|
| 2022 |
Davidson J, Nicholas K, Young J, Conrady DG, Mayclin S, Subramanian S, Staker BL, Myler PJ, Asojo OA. Crystal structure of a putative short-chain dehydrogenase/reductase from Paraburkholderia xenovorans. Acta Crystallographica. Section F, Structural Biology Communications. 78: 25-30. PMID 34981772 DOI: 10.1107/S2053230X21012632 |
0.35 |
|
| 2021 |
Tillery L, Barrett K, Goldstein J, Lassner JW, Osterhout B, Tran NL, Xu L, Young RM, Craig J, Chun I, Dranow DM, Abendroth J, Delker SL, Davies DR, Mayclin SJ, ... ... Staker B, et al. Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba. Plos One. 16: e0241738. PMID 33760815 DOI: 10.1371/journal.pone.0241738 |
0.314 |
|
| 2020 |
Santos JC, Vieira ML, Abendroth J, Lin T, Staker BL, Myler PJ, Nascimento ALTO. Structural analysis of CACHE domain of the McpA chemoreceptor from Leptospira interrogans. Biochemical and Biophysical Research Communications. PMID 33097187 DOI: 10.1016/j.bbrc.2020.10.013 |
0.322 |
|
| 2018 |
Dumais M, Davies DR, Lin T, Staker BL, Myler PJ, Van Voorhis WC. Structure and analysis of nucleoside diphosphate kinase from Borrelia burgdorferi prepared in a transition-state complex with ADP and vanadate moieties. Acta Crystallographica. Section F, Structural Biology Communications. 74: 373-384. PMID 29870023 DOI: 10.1107/S2053230X18007392 |
0.392 |
|
| 2018 |
Asojo OA, Dranow DM, Serbzhinskiy D, Subramanian S, Staker B, Edwards TE, Myler PJ. Crystal structure of chorismate mutase from Burkholderia thailandensis. Acta Crystallographica. Section F, Structural Biology Communications. 74: 294-299. PMID 29717997 DOI: 10.1107/S2053230X1800506X |
0.384 |
|
| 2017 |
Moen SO, Edwards TE, Dranow DM, Clifton MC, Sankaran B, Van Voorhis WC, Sharma A, Manoil C, Staker BL, Myler PJ, Lorimer DD. Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms. Scientific Reports. 7: 223. PMID 28303005 DOI: 10.1038/S41598-017-00367-6 |
0.369 |
|
| 2016 |
Cala AR, Nadeau MT, Abendroth J, Staker BL, Reers AR, Weatherhead AW, Dobson RC, Myler PJ, Hudson AO. The crystal structure of dihydrodipicolinate reductase from the human-pathogenic bacterium Bartonella henselae strain Houston-1 at 2.3 Å resolution. Acta Crystallographica. Section F, Structural Biology Communications. 72: 885-891. PMID 27917836 DOI: 10.1107/S2053230X16018525 |
0.326 |
|
| 2015 |
Gillespie JJ, Phan IQ, Scheib H, Subramanian S, Edwards TE, Lehman SS, Piitulainen H, Sayeedur Rahman M, Rennoll-Bankert KE, Staker BL, Taira S, Stacy R, Myler PJ, Azad AF, Pulliainen AT. Structural Insight into How Bacteria Prevent Interference between Multiple Divergent Type IV Secretion Systems. Mbio. 6. PMID 26646013 DOI: 10.1128/Mbio.01867-15 |
0.337 |
|
| 2015 |
Helgren TR, Wangtrakuldee P, Staker BL, Hagen TJ. Advances in Bacterial Methionine Aminopeptidase Inhibition. Current Topics in Medicinal Chemistry. PMID 26268344 DOI: 10.2174/1568026615666150813145410 |
0.469 |
|
| 2015 |
Moen SO, Fairman JW, Barnes SR, Sullivan A, Nakazawa-Hewitt S, Van Voorhis WC, Staker BL, Lorimer DD, Myler PJ, Edwards TE. Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP. Acta Crystallographica. Section F, Structural Biology Communications. 71: 609-14. PMID 25945716 DOI: 10.1107/S2053230X15006883 |
0.33 |
|
| 2015 |
Serbzhinskiy DA, Clifton MC, Sankaran B, Staker BL, Edwards TE, Myler PJ. Structure of an ADP-ribosylation factor, ARF1, from Entamoeba histolytica bound to Mg(2+)-GDP. Acta Crystallographica. Section F, Structural Biology Communications. 71: 594-9. PMID 25945714 DOI: 10.1107/S2053230X15004677 |
0.431 |
|
| 2015 |
Lorimer DD, Choi R, Abramov A, Nakazawa Hewitt S, Gardberg AS, Van Voorhis WC, Staker BL, Myler PJ, Edwards TE. Structures of a histidine triad family protein from Entamoeba histolytica bound to sulfate, AMP and GMP. Acta Crystallographica. Section F, Structural Biology Communications. 71: 572-6. PMID 25945711 DOI: 10.1107/S2053230X1500237X |
0.438 |
|
| 2015 |
Abendroth J, Choi R, Wall A, Clifton MC, Lukacs CM, Staker BL, Van Voorhis W, Myler P, Lorimer DD, Edwards TE. Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. Acta Crystallographica. Section F, Structural Biology Communications. 71: 566-71. PMID 25945710 DOI: 10.1107/S2053230X15001831 |
0.462 |
|
| 2015 |
Edwards TE, Gardberg AS, Phan IQ, Zhang Y, Staker BL, Myler PJ, Lorimer DD. Structure of uridine diphosphate N-acetylglucosamine pyrophosphorylase from Entamoeba histolytica. Acta Crystallographica. Section F, Structural Biology Communications. 71: 560-5. PMID 25945709 DOI: 10.1107/S2053230X1500179X |
0.418 |
|
| 2015 |
Buchko GW, Abendroth J, Clifton MC, Robinson H, Zhang Y, Hewitt SN, Staker BL, Edwards TE, Van Voorhis WC, Myler PJ. Structure of a CutA1 divalent-cation tolerance protein from Cryptosporidium parvum, the protozoal parasite responsible for cryptosporidiosis. Acta Crystallographica. Section F, Structural Biology Communications. 71: 522-30. PMID 25945704 DOI: 10.1107/S2053230X14028210 |
0.411 |
|
| 2015 |
Edwards TE, Baugh L, Bullen J, Baydo RO, Witte P, Thompkins K, Phan IQ, Abendroth J, Clifton MC, Sankaran B, Van Voorhis WC, Myler PJ, Staker BL, Grundner C, Lorimer DD. Crystal structures of Mycobacterial MeaB and MMAA-like GTPases. Journal of Structural and Functional Genomics. 16: 91-9. PMID 25832174 DOI: 10.1007/S10969-015-9197-2 |
0.435 |
|
| 2015 |
Baugh L, Phan I, Begley DW, Clifton MC, Armour B, Dranow DM, Taylor BM, Muruthi MM, Abendroth J, Fairman JW, Fox D, Dieterich SH, Staker BL, Gardberg AS, Choi R, et al. Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinburgh, Scotland). 95: 142-8. PMID 25613812 DOI: 10.1016/J.Tube.2014.12.003 |
0.427 |
|
| 2014 |
Moen SO, Abendroth J, Fairman JW, Baydo RO, Bullen J, Kirkwood JL, Barnes SR, Raymond AC, Begley DW, Henkel G, McCormack K, Tam VC, Phan I, Staker BL, Stacy R, et al. Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1. Scientific Reports. 4: 5944. PMID 25089892 DOI: 10.1038/Srep05944 |
0.376 |
|
| 2014 |
Linford AS, Jiang NM, Edwards TE, Sherman NE, Van Voorhis WC, Stewart LJ, Myler PJ, Staker BL, Petri WA. Crystal structure and putative substrate identification for the Entamoeba histolytica low molecular weight tyrosine phosphatase. Molecular and Biochemical Parasitology. 193: 33-44. PMID 24548880 DOI: 10.1016/J.Molbiopara.2014.01.003 |
0.423 |
|
| 2014 |
Begley DW, Fox D, Jenner D, Juli C, Pierce PG, Abendroth J, Muruthi M, Safford K, Anderson V, Atkins K, Barnes SR, Moen SO, Raymond AC, Stacy R, Myler PJ, ... Staker BL, et al. A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrobial Agents and Chemotherapy. 58: 1458-67. PMID 24366729 DOI: 10.1128/Aac.01875-13 |
0.415 |
|
| 2014 |
Abendroth J, Ollodart A, Andrews ES, Myler PJ, Staker BL, Edwards TE, Arcus VL, Grundner C. Mycobacterium tuberculosis Rv2179c protein establishes a new exoribonuclease family with broad phylogenetic distribution. The Journal of Biological Chemistry. 289: 2139-47. PMID 24311791 DOI: 10.1074/Jbc.M113.525683 |
0.401 |
|
| 2013 |
Zhang Z, Jakkaraju S, Blain J, Gogol K, Zhao L, Hartley RC, Karlsson CA, Staker BL, Edwards TE, Stewart LJ, Myler PJ, Clare M, Begley DW, Horn JR, Hagen TJ. Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei. Bioorganic & Medicinal Chemistry Letters. 23: 6860-3. PMID 24157367 DOI: 10.1016/J.Bmcl.2013.09.101 |
0.372 |
|
| 2013 |
Armour BL, Barnes SR, Moen SO, Smith E, Raymond AC, Fairman JW, Stewart LJ, Staker BL, Begley DW, Edwards TE, Lorimer DD. Multi-target parallel processing approach for gene-to-structure determination of the influenza polymerase PB2 subunit. Journal of Visualized Experiments : Jove. PMID 23851357 DOI: 10.3791/4225 |
0.424 |
|
| 2013 |
Baugh L, Gallagher LA, Patrapuvich R, Clifton MC, Gardberg AS, Edwards TE, Armour B, Begley DW, Dieterich SH, Dranow DM, Abendroth J, Fairman JW, Fox D, Staker BL, Phan I, et al. Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One. 8: e53851. PMID 23382856 DOI: 10.1371/Journal.Pone.0053851 |
0.477 |
|
| 2011 |
Edwards TE, Abramov AB, Smith ER, Baydo RO, Leonard JT, Leibly DJ, Thompkins KB, Clifton MC, Gardberg AS, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ. Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis. Bmc Structural Biology. 11: 39. PMID 21995815 DOI: 10.1186/1472-6807-11-39 |
0.347 |
|
| 2011 |
Clifton MC, Abendroth J, Edwards TE, Leibly DJ, Gillespie AK, Ferrell M, Dieterich SH, Exley I, Staker BL, Myler PJ, Van Voorhis WC, Stewart LJ. Structure of the cystathionine γ-synthase MetB from Mycobacterium ulcerans. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1154-8. PMID 21904066 DOI: 10.1107/S1744309111029575 |
0.388 |
|
| 2011 |
Subramanian S, Abendroth J, Phan IQ, Olsen C, Staker BL, Napuli A, Van Voorhis WC, Stacy R, Myler PJ. Structure of 3-ketoacyl-(acyl-carrier-protein) reductase from Rickettsia prowazekii at 2.25 Å resolution. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1118-22. PMID 21904060 DOI: 10.1107/S1744309111030673 |
0.456 |
|
| 2011 |
Ferrell M, Abendroth J, Zhang Y, Sankaran B, Edwards TE, Staker BL, Van Voorhis WC, Stewart LJ, Myler PJ. Structure of aldose reductase from Giardia lamblia. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1113-7. PMID 21904059 DOI: 10.1107/S1744309111030879 |
0.41 |
|
| 2011 |
Abendroth J, Sankaran B, Edwards TE, Gardberg AS, Dieterich S, Bhandari J, Napuli AJ, Van Voorhis WC, Staker BL, Myler PJ, Stewart LJ. BrabA.11339.a: anomalous diffraction and ligand binding guide towards the elucidation of the function of a 'putative β-lactamase-like protein' from Brucella melitensis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1106-12. PMID 21904058 DOI: 10.1107/S1744309111010220 |
0.379 |
|
| 2011 |
Buchko GW, Edwards TE, Abendroth J, Arakaki TL, Law L, Napuli AJ, Hewitt SN, Van Voorhis WC, Stewart LJ, Staker BL, Myler PJ. Structure of a Nudix hydrolase (MutT) in the Mg(2+)-bound state from Bartonella henselae, the bacterium responsible for cat scratch fever. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1078-83. PMID 21904053 DOI: 10.1107/S1744309111011559 |
0.44 |
|
| 2011 |
Begley DW, Edwards TE, Raymond AC, Smith ER, Hartley RC, Abendroth J, Sankaran B, Lorimer DD, Myler PJ, Staker BL, Stewart LJ. Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1070-7. PMID 21904052 DOI: 10.1107/S1744309111029009 |
0.4 |
|
| 2011 |
Begley DW, Davies DR, Hartley RC, Hewitt SN, Rychel AL, Myler PJ, Van Voorhis WC, Staker BL, Stewart LJ. Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1060-9. PMID 21904051 DOI: 10.1107/S1744309111014436 |
0.459 |
|
| 2011 |
Gardberg A, Sankaran B, Davies D, Bhandari J, Staker B, Stewart L. Structure of fructose bisphosphate aldolase from Encephalitozoon cuniculi Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 67: 1055-1059. PMID 21904050 DOI: 10.1107/S1744309111021841 |
0.453 |
|
| 2011 |
Gardberg A, Abendroth J, Bhandari J, Sankaran B, Staker B. Structure of fructose bisphosphate aldolase from Bartonella henselae bound to fructose 1,6-bisphosphate. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1051-4. PMID 21904049 DOI: 10.1107/S174430911101894X |
0.464 |
|
| 2011 |
Davies DR, Staker BL, Abendroth JA, Edwards TE, Hartley R, Leonard J, Kim H, Rychel AL, Hewitt SN, Myler PJ, Stewart LJ. An ensemble of structures of Burkholderia pseudomallei 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1044-50. PMID 21904048 DOI: 10.1107/S1744309111030405 |
0.41 |
|
| 2011 |
Edwards TE, Bryan CM, Leibly DJ, Dieterich SH, Abendroth J, Sankaran B, Sivam D, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ. Structures of a putative ζ-class glutathione S-transferase from the pathogenic fungus Coccidioides immitis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1038-43. PMID 21904047 DOI: 10.1107/S1744309111009493 |
0.452 |
|
| 2011 |
Edwards TE, Leibly DJ, Bhandari J, Statnekov JB, Phan I, Dieterich SH, Abendroth J, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ. Structures of phosphopantetheine adenylyltransferase from Burkholderia pseudomallei. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1032-7. PMID 21904046 DOI: 10.1107/S1744309111004349 |
0.45 |
|
| 2011 |
Smith ER, Begley DW, Anderson V, Raymond AC, Haffner TE, Robinson JI, Edwards TE, Duncan N, Gerdts CJ, Mixon MB, Nollert P, Staker BL, Stewart LJ. The Protein Maker: an automated system for high-throughput parallel purification. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1015-21. PMID 21904043 DOI: 10.1107/S1744309111028776 |
0.396 |
|
| 2011 |
Raymond A, Haffner T, Ng N, Lorimer D, Staker B, Stewart L. Gene design, cloning and protein-expression methods for high-value targets at the Seattle Structural Genomics Center for Infectious Disease. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 992-7. PMID 21904039 DOI: 10.1107/S1744309111026698 |
0.398 |
|
| 2011 |
Lorimer D, Raymond A, Mixon M, Burgin A, Staker B, Stewart L. Gene Composer in a structural genomics environment. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 985-91. PMID 21904038 DOI: 10.1107/S1744309111027424 |
0.395 |
|
| 2011 |
Stacy R, Begley DW, Phan I, Staker BL, Van Voorhis WC, Varani G, Buchko GW, Stewart LJ, Myler PJ. Structural genomics of infectious disease drug targets: the SSGCID. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 979-84. PMID 21904037 DOI: 10.1107/S1744309111029204 |
0.402 |
|
| 2011 |
Begley DW, Davies DR, Hartley RC, Edwards TE, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ. Fragment screening of infectious disease targets in a structural genomics environment. Methods in Enzymology. 493: 533-56. PMID 21371605 DOI: 10.1016/B978-0-12-381274-2.00021-2 |
0.423 |
|
| 2011 |
Davies DR, Begley DW, Hartley RC, Staker BL, Stewart LJ. Predicting the success of fragment screening by X-ray crystallography. Methods in Enzymology. 493: 91-114. PMID 21371588 DOI: 10.1016/B978-0-12-381274-2.00004-2 |
0.361 |
|
| 2011 |
Abendroth J, Gardberg AS, Robinson JI, Christensen JS, Staker BL, Myler PJ, Stewart LJ, Edwards TE. SAD phasing using iodide ions in a high-throughput structural genomics environment. Journal of Structural and Functional Genomics. 12: 83-95. PMID 21359836 DOI: 10.1007/S10969-011-9101-7 |
0.416 |
|
| 2011 |
Begley DW, Hartley RC, Davies DR, Edwards TE, Leonard JT, Abendroth J, Burris CA, Bhandari J, Myler PJ, Staker BL, Stewart LJ. Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. Journal of Structural and Functional Genomics. 12: 63-76. PMID 21359640 DOI: 10.1007/S10969-011-9102-6 |
0.492 |
|
| 2010 |
Gerdts CJ, Stahl GL, Napuli A, Staker B, Abendroth J, Edwards TE, Myler P, Van Voorhis W, Nollert P, Stewart LJ. Nanovolume optimization of protein crystal growth using the microcapillary protein crystallization system. Journal of Applied Crystallography. 43: 1078-1083. PMID 22477778 DOI: 10.1107/S0021889810027378 |
0.36 |
|
| 2010 |
Edwards TE, Phan I, Abendroth J, Dieterich SH, Masoudi A, Guo W, Hewitt SN, Kelley A, Leibly D, Brittnacher MJ, Staker BL, Miller SI, Van Voorhis WC, Myler PJ, Stewart LJ. Structure of a Burkholderia pseudomallei trimeric autotransporter adhesin head. Plos One. 5. PMID 20862217 DOI: 10.1371/Journal.Pone.0012803 |
0.32 |
|
| 2010 |
Abendroth J, McCormick MS, Edwards TE, Staker B, Loewen R, Gifford M, Rifkin J, Mayer C, Guo W, Zhang Y, Myler P, Kelley A, Analau E, Hewitt SN, Napuli AJ, et al. X-ray structure determination of the glycine cleavage system protein H of Mycobacterium tuberculosis using an inverse Compton synchrotron X-ray source. Journal of Structural and Functional Genomics. 11: 91-100. PMID 20364333 DOI: 10.1007/S10969-010-9087-6 |
0.321 |
|
| 2010 |
Buchko GW, Robinson H, Abendroth J, Staker BL, Myler PJ. Structural characterization of Burkholderia pseudomallei adenylate kinase (Adk): profound asymmetry in the crystal structure of the 'open' state. Biochemical and Biophysical Research Communications. 394: 1012-7. PMID 20331978 DOI: 10.1016/J.Bbrc.2010.03.112 |
0.46 |
|
| 2010 |
Burgin AB, Magnusson OT, Singh J, Witte P, Staker BL, Bjornsson JM, Thorsteinsdottir M, Hrafnsdottir S, Hagen T, Kiselyov AS, Stewart LJ, Gurney ME. Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety. Nature Biotechnology. 28: 63-70. PMID 20037581 DOI: 10.1038/Nbt.1598 |
0.394 |
|
| 2009 |
Myler PJ, Stacy R, Stewart L, Staker BL, Van Voorhis WC, Varani G, Buchko GW. The Seattle Structural Genomics Center for Infectious Disease (SSGCID). Infectious Disorders Drug Targets. 9: 493-506. PMID 19594426 DOI: 10.2174/187152609789105687 |
0.38 |
|
| 2008 |
Gerdts CJ, Elliott M, Lovell S, Mixon MB, Napuli AJ, Staker BL, Nollert P, Stewart L. The plug-based nanovolume Microcapillary Protein Crystallization System (MPCS). Acta Crystallographica. Section D, Biological Crystallography. 64: 1116-22. PMID 19020349 DOI: 10.1107/S0907444908028060 |
0.349 |
|
| 2008 |
Singh J, Salcius M, Liu SW, Staker BL, Mishra R, Thurmond J, Michaud G, Mattoon DR, Printen J, Christensen J, Bjornsson JM, Pollok BA, Kiledjian M, Stewart L, Jarecki J, et al. DcpS as a therapeutic target for spinal muscular atrophy. Acs Chemical Biology. 3: 711-22. PMID 18839960 DOI: 10.1021/Cb800120T |
0.39 |
|
| 2006 |
Marchand C, Antony S, Kohn KW, Cushman M, Ioanoviciu A, Staker BL, Burgin AB, Stewart L, Pommier Y. A novel norindenoisoquinoline structure reveals a common interfacial inhibitor paradigm for ternary trapping of the topoisomerase I-DNA covalent complex. Molecular Cancer Therapeutics. 5: 287-95. PMID 16505102 DOI: 10.1158/1535-7163.Mct-05-0456 |
0.353 |
|
| 2005 |
Ioanoviciu A, Antony S, Pommier Y, Staker BL, Stewart L, Cushman M. Synthesis and mechanism of action studies of a series of norindenoisoquinoline topoisomerase I poisons reveal an inhibitor with a flipped orientation in the ternary DNA-enzyme-inhibitor complex as determined by X-ray crystallographic analysis. Journal of Medicinal Chemistry. 48: 4803-14. PMID 16033260 DOI: 10.1021/Jm050076B |
0.356 |
|
| 2005 |
Raymond AC, Staker BL, Burgin AB. Substrate specificity of tyrosyl-DNA phosphodiesterase I (Tdp1). The Journal of Biological Chemistry. 280: 22029-35. PMID 15811850 DOI: 10.1074/Jbc.M502148200 |
0.333 |
|
| 2005 |
Staker BL, Feese MD, Cushman M, Pommier Y, Zembower D, Stewart L, Burgin AB. Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex. Journal of Medicinal Chemistry. 48: 2336-45. PMID 15801827 DOI: 10.1021/Jm049146P |
0.355 |
|
| 2004 |
Hager J, Staker BL, Jakob U. Substrate binding analysis of the 23S rRNA methyltransferase RrmJ. Journal of Bacteriology. 186: 6634-42. PMID 15375145 DOI: 10.1128/Jb.186.19.6634-6642.2004 |
0.41 |
|
| 2004 |
Chrencik JE, Staker BL, Burgin AB, Pourquier P, Pommier Y, Stewart L, Redinbo MR. Mechanisms of camptothecin resistance by human topoisomerase I mutations. Journal of Molecular Biology. 339: 773-84. PMID 15165849 DOI: 10.1016/J.Jmb.2004.03.077 |
0.388 |
|
| 2004 |
Raymond AC, Rideout MC, Staker B, Hjerrild K, Burgin AB. Analysis of human tyrosyl-DNA phosphodiesterase I catalytic residues. Journal of Molecular Biology. 338: 895-906. PMID 15111055 DOI: 10.1016/J.Jmb.2004.03.013 |
0.413 |
|
| 2004 |
Towler P, Staker B, Prasad SG, Menon S, Tang J, Parsons T, Ryan D, Fisher M, Williams D, Dales NA, Patane MA, Pantoliano MW. ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis. The Journal of Biological Chemistry. 279: 17996-8007. PMID 14754895 DOI: 10.1074/Jbc.M311191200 |
0.442 |
|
| 2003 |
Fox BM, Xiao X, Antony S, Kohlhagen G, Pommier Y, Staker BL, Stewart L, Cushman M. Design, synthesis, and biological evaluation of cytotoxic 11-alkenylindenoisoquinoline topoisomerase I inhibitors and indenoisoquinoline-camptothecin hybrids. Journal of Medicinal Chemistry. 46: 3275-82. PMID 12852757 DOI: 10.1021/Jm0300476 |
0.334 |
|
| 2002 |
Staker BL, Hjerrild K, Feese MD, Behnke CA, Burgin AB, Stewart L. The mechanism of topoisomerase I poisoning by a camptothecin analog. Proceedings of the National Academy of Sciences of the United States of America. 99: 15387-92. PMID 12426403 DOI: 10.1073/Pnas.242259599 |
0.382 |
|
| 2002 |
Hager J, Staker BL, Bugl H, Jakob U. Active site in RrmJ, a heat shock-induced methyltransferase. The Journal of Biological Chemistry. 277: 41978-86. PMID 12181314 DOI: 10.1074/Jbc.M205423200 |
0.379 |
|
| 2000 |
Bügl H, Fauman EB, Staker BL, Zheng F, Kushner SR, Saper MA, Bardwell JC, Jakob U. RNA methylation under heat shock control. Molecular Cell. 6: 349-60. PMID 10983982 DOI: 10.1016/S1097-2765(00)00035-6 |
0.603 |
|
| 2000 |
Staker BL, Korber P, Bardwell JC, Saper MA. Structure of Hsp15 reveals a novel RNA-binding motif. The Embo Journal. 19: 749-57. PMID 10675344 DOI: 10.1093/Emboj/19.4.749 |
0.609 |
|
| Show low-probability matches. |