Year |
Citation |
Score |
2024 |
Damayanti NP, Cordova RA, Rupert C, Delle Fontane I, Shen L, Orsi S, Klunk AJ, Linehan WM, Staschke KA, Hollenhorst PC, Heppner DE, Pili R. TFE3-splicing factor fusions represent functional drivers and druggable targets in translocation renal cell carcinoma. Cancer Research. PMID 38266162 DOI: 10.1158/0008-5472.CAN-23-1789 |
0.325 |
|
2023 |
Greulich BM, Rajendran S, Downing NF, Nicholas TR, Hollenhorst PC. A complex with poly(A) binding protein and EWS facilitates the transcriptional function of oncogenic ETS transcription factors in prostate cells. The Journal of Biological Chemistry. 105453. PMID 37956771 DOI: 10.1016/j.jbc.2023.105453 |
0.409 |
|
2021 |
Nicholas TR, Metcalf SA, Greulich BM, Hollenhorst PC. Androgen signaling connects short isoform production to breakpoint formation at Ewing sarcoma breakpoint region 1. Nar Cancer. 3: zcab033. PMID 34409300 DOI: 10.1093/narcan/zcab033 |
0.385 |
|
2021 |
Strittmatter BG, Jerde TJ, Hollenhorst PC. Ras/ERK and PI3K/AKT signaling differentially regulate oncogenic ERG mediated transcription in prostate cells. Plos Genetics. 17: e1009708. PMID 34314419 DOI: 10.1371/journal.pgen.1009708 |
0.417 |
|
2021 |
Greulich BM, Plotnik JP, Jerde TJ, Hollenhorst PC. Toll-like receptor 4 signaling activates ERG function in prostate cancer and provides a therapeutic target. Nar Cancer. 3: zcaa046. PMID 33554122 DOI: 10.1093/narcan/zcaa046 |
0.325 |
|
2020 |
Nicholas TR, Meng J, Greulich BM, Morris TS, Hollenhorst PC. --A high-throughput screen identifies inhibitors of the interaction between the oncogenic transcription factor ERG and the cofactor EWS. Plos One. 15: e0238999. PMID 32915889 DOI: 10.1371/Journal.Pone.0238999 |
0.371 |
|
2019 |
Nicholas TR, Strittmatter BG, Hollenhorst PC. Oncogenic ETS Factors in Prostate Cancer. Advances in Experimental Medicine and Biology. 1210: 409-436. PMID 31900919 DOI: 10.1007/978-3-030-32656-2_18 |
0.461 |
|
2019 |
Strittmatter BG, Hollenhorst P. Abstract 5257: Activation of the oncogene ERG by the Ras/ERK and PI3K/AKT pathways Cancer Research. 79: 5257-5257. DOI: 10.1158/1538-7445.Sabcs18-5257 |
0.433 |
|
2019 |
Nicholas T, Strittmatter B, Jerde T, Hollenhorst P. Mechanisms of ETS family transcription factors that promote prostate cancer European Urology Supplements. 18: e3040. DOI: 10.1016/s1569-9056(19)33290-7 |
0.341 |
|
2018 |
Budka JA, Ferris MW, Capone MJ, Hollenhorst PC. Common ELF1 deletion in prostate cancer bolsters oncogenic ETS function, inhibits senescence and promotes docetaxel resistance. Genes & Cancer. 9: 198-214. PMID 30603056 DOI: 10.18632/Genesandcancer.182 |
0.518 |
|
2018 |
Madison BJ, Clark KA, Bhachech N, Hollenhorst P, Graves BJ, Currie SL. Electrostatic repulsion causes anticooperative DNA binding between tumor suppressor ETS transcription factors and JUN-FOS at composite DNA sites. The Journal of Biological Chemistry. PMID 30315111 DOI: 10.1074/Jbc.Ra118.003352 |
0.666 |
|
2018 |
Tomar S, Plotnik JP, Haley J, Scantland J, Sheikh Z, Emerson R, Lenz D, Hollenhorst PC, Mitra AK. Abstract A34: Induction of a novel ETS1/FAK pathway in metastasizing ovarian cancer cells by the omental microenvironment primes them for metastatic colonization Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Ovca17-A34 |
0.401 |
|
2018 |
Kedage V, Nicholas TR, Strittmatter BG, Selvaraj N, Budka JA, Jerde TJ, Hollenhorst PC. Abstract A023: Regulation of ERG function in prostate cells by phosphorylation and interaction with Ewing’s sarcoma breakpoint protein EWS Cancer Research. 78. DOI: 10.1158/1538-7445.Prca2017-A023 |
0.468 |
|
2017 |
Tomar S, Plotnik JP, Haley J, Scantland J, Dasari S, Sheikh Z, Emerson R, Lenz D, Hollenhorst PC, Mitra AK. ETS1 induction by the microenvironment promotes ovarian cancer metastasis through focal adhesion kinase. Cancer Letters. 414: 190-204. PMID 29174800 DOI: 10.1016/J.Canlet.2017.11.012 |
0.48 |
|
2017 |
Kedage V, Strittmatter BG, Dausinas PB, Hollenhorst PC. Phosphorylation of the oncogenic transcription factor ERG in prostate cells dissociates polycomb repressive complex 2 allowing target gene activation. The Journal of Biological Chemistry. PMID 28887309 DOI: 10.1074/Jbc.M117.796458 |
0.482 |
|
2017 |
Potu H, Peterson LF, Kandarpa M, Pal A, Sun H, Durham A, Harms PW, Hollenhorst PC, Eskiocak U, Talpaz M, Donato NJ. Usp9x regulates Ets-1 ubiquitination and stability to control NRAS expression and tumorigenicity in melanoma. Nature Communications. 8: 14449. PMID 28198367 DOI: 10.1038/Ncomms14449 |
0.423 |
|
2017 |
Plotnik JP, Hollenhorst PC. Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2. Nucleic Acids Research. PMID 28119415 DOI: 10.1093/Nar/Gkx039 |
0.475 |
|
2017 |
Plotnik JP, Hollenhorst PC. Genome-Wide Analysis of RAS/ERK Signaling Targets. Methods in Molecular Biology (Clifton, N.J.). 1487: 277-288. PMID 27924575 DOI: 10.1007/978-1-4939-6424-6_21 |
0.383 |
|
2017 |
Kedage V, Selvaraj N, Nicholas TR, Budka JA, Jerde TJ, Hollenhorst PC. Abstract 3510: A role for the Ewing’s sarcoma breakpoint protein EWS in ERG-induced prostate tumorigenesis Cancer Research. 77: 3510-3510. DOI: 10.1158/1538-7445.Am2017-3510 |
0.308 |
|
2016 |
Kedage V, Selvaraj N, Nicholas TR, Budka JA, Plotnik JP, Jerde TJ, Hollenhorst PC. An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer. Cell Reports. 17: 1289-1301. PMID 27783944 DOI: 10.1016/J.Celrep.2016.10.001 |
0.466 |
|
2015 |
Selvaraj N, Kedage V, Hollenhorst PC. Comparison of MAPK specificity across the ETS transcription factor family identifies a high-affinity ERK interaction required for ERG function in prostate cells. Cell Communication and Signaling : Ccs. 13: 12. PMID 25885538 DOI: 10.1186/S12964-015-0089-7 |
0.561 |
|
2015 |
Selvaraj N, Budka JA, Ferris MW, Plotnik JP, Hollenhorst PC. Extracellular signal-regulated kinase signaling regulates the opposing roles of JUN family transcription factors at ETS/AP-1 sites and in cell migration. Molecular and Cellular Biology. 35: 88-100. PMID 25332240 DOI: 10.1128/Mcb.00982-14 |
0.52 |
|
2014 |
Plotnik JP, Budka JA, Ferris MW, Hollenhorst PC. ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells. Nucleic Acids Research. 42: 11928-40. PMID 25294825 DOI: 10.1093/Nar/Gku929 |
0.501 |
|
2014 |
Selvaraj N, Budka JA, Ferris MW, Jerde TJ, Hollenhorst PC. Prostate cancer ETS rearrangements switch a cell migration gene expression program from RAS/ERK to PI3K/AKT regulation. Molecular Cancer. 13: 61. PMID 24642271 DOI: 10.1186/1476-4598-13-61 |
0.414 |
|
2012 |
Foley J, Nickerson N, Riese DJ, Hollenhorst PC, Lorch G, Foley AM. At the crossroads: EGFR and PTHrP signaling in cancer-mediated diseases of bone. Odontology / the Society of the Nippon Dental University. 100: 109-29. PMID 22684584 DOI: 10.1007/S10266-012-0070-5 |
0.312 |
|
2012 |
Hollenhorst PC. RAS/ERK pathway transcriptional regulation through ETS/AP-1 binding sites. Small Gtpases. 3: 154-8. PMID 22653334 DOI: 10.4161/Sgtp.19630 |
0.532 |
|
2012 |
Hollenhorst PC, Ferris MW, Hull MA, Chae H, Kim S, Graves BJ. Abstract PR1: Oncogenic ETS over-expression mimics RAS/MAPK signaling in prostate cells Cancer Research. 72: PR1-PR1. DOI: 10.1158/1538-7445.PRCA2012-PR1 |
0.546 |
|
2012 |
Hollenhorst PC, Ferris MW, Hull MA, Chae H, Kim S, Graves BJ. Abstract 3090: Oncogenic ETS transcription factors bind ETS/AP-1 sequences and activate a RAS/MAPK gene expression program in the absence of MAPK activation Cancer Research. 72: 3090-3090. DOI: 10.1158/1538-7445.Am2012-3090 |
0.554 |
|
2011 |
Hollenhorst PC, Ferris MW, Hull MA, Chae H, Kim S, Graves BJ. Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells. Genes & Development. 25: 2147-57. PMID 22012618 DOI: 10.1101/Gad.17546311 |
0.679 |
|
2011 |
Hollenhorst PC, McIntosh LP, Graves BJ. Genomic and biochemical insights into the specificity of ETS transcription factors. Annual Review of Biochemistry. 80: 437-71. PMID 21548782 DOI: 10.1146/Annurev.Biochem.79.081507.103945 |
0.684 |
|
2011 |
Hollenhorst PC, Paul L, Ferris MW, Graves BJ. The ETS gene ETV4 is required for anchorage-independent growth and a cell proliferation gene expression program in PC3 prostate cells. Genes & Cancer. 1: 1044-1052. PMID 21373373 DOI: 10.1177/1947601910395578 |
0.66 |
|
2010 |
Oler AJ, Alla RK, Roberts DN, Wong A, Hollenhorst PC, Chandler KJ, Cassiday PA, Nelson CA, Hagedorn CH, Graves BJ, Cairns BR. Human RNA polymerase III transcriptomes and relationships to Pol II promoter chromatin and enhancer-binding factors. Nature Structural & Molecular Biology. 17: 620-8. PMID 20418882 DOI: 10.1038/Nsmb.1801 |
0.691 |
|
2010 |
Clement NL, Snell Q, Clement MJ, Hollenhorst PC, Purwar J, Graves BJ, Cairns BR, Johnson WE. The GNUMAP algorithm: unbiased probabilistic mapping of oligonucleotides from next-generation sequencing. Bioinformatics (Oxford, England). 26: 38-45. PMID 19861355 DOI: 10.1093/Bioinformatics/Btp614 |
0.519 |
|
2009 |
Hollenhorst PC, Chandler KJ, Poulsen RL, Johnson WE, Speck NA, Graves BJ. DNA specificity determinants associate with distinct transcription factor functions. Plos Genetics. 5: e1000778. PMID 20019798 DOI: 10.1371/Journal.Pgen.1000778 |
0.74 |
|
2008 |
Gangwal K, Sankar S, Hollenhorst PC, Kinsey M, Haroldsen SC, Shah AA, Boucher KM, Watkins WS, Jorde LB, Graves BJ, Lessnick SL. Microsatellites as EWS/FLI response elements in Ewing's sarcoma. Proceedings of the National Academy of Sciences of the United States of America. 105: 10149-54. PMID 18626011 DOI: 10.1073/Pnas.0801073105 |
0.696 |
|
2007 |
Hollenhorst PC, Shah AA, Hopkins C, Graves BJ. Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family. Genes & Development. 21: 1882-94. PMID 17652178 DOI: 10.1101/Gad.1561707 |
0.691 |
|
2004 |
Hollenhorst PC, Jones DA, Graves BJ. Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors. Nucleic Acids Research. 32: 5693-702. PMID 15498926 DOI: 10.1093/Nar/Gkh906 |
0.699 |
|
2001 |
Hollenhorst PC, Pietz G, Fox CA. Mechanisms controlling differential promoter-occupancy by the yeast forkhead proteins Fkh1p and Fkh2p: implications for regulating the cell cycle and differentiation. Genes & Development. 15: 2445-56. PMID 11562353 DOI: 10.1101/Gad.906201 |
0.635 |
|
2000 |
Hollenhorst PC, Bose ME, Mielke MR, Müller U, Fox CA. Forkhead genes in transcriptional silencing, cell morphology and the cell cycle. Overlapping and distinct functions for FKH1 and FKH2 in Saccharomyces cerevisiae. Genetics. 154: 1533-48. PMID 10747051 |
0.713 |
|
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