| Year |
Citation |
Score |
| 2024 |
Wright KM, Nathan S, Jiang H, Xia W, Kim H, Chakouri N, Nwafor JN, Fossier L, Srinivasan L, Chen Z, Boronina T, Post J, Paul S, Cole RN, Ben-Johny M, ... ... Gabelli SB, et al. NEDD4L intramolecular Interactions regulate its auto- and substrate Na1.5 ubiquitination. The Journal of Biological Chemistry. 105715. PMID 38309503 DOI: 10.1016/j.jbc.2024.105715 |
0.462 |
|
| 2023 |
Wright KM, Jiang H, Xia W, Murphy MB, Boronina TN, Nwafor JN, Kim H, Iheanacho AM, Azurmendi PA, Cole RN, Cole PA, Gabelli SB. The C-Terminal of Na1.7 Is Ubiquitinated by NEDD4L. Acs Bio & Med Chem Au. 3: 516-527. PMID 38144259 DOI: 10.1021/acsbiomedchemau.3c00031 |
0.756 |
|
| 2023 |
Wright KM, DiNapoli SR, Miller MS, Aitana Azurmendi P, Zhao X, Yu Z, Chakrabarti M, Shi W, Douglass J, Hwang MS, Hsiue EH, Mog BJ, Pearlman AH, Paul S, Konig MF, ... ... Gabelli SB, et al. Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen. Nature Communications. 14: 5063. PMID 37604828 DOI: 10.1038/s41467-023-40821-w |
0.794 |
|
| 2023 |
Lu S, Mattox AK, Aitana Azurmendi P, Christodoulou I, Wright KM, Popoli M, Chen Z, Sur S, Li Y, Bonifant CL, Bettegowda C, Papadopoulos N, Zhou S, Gabelli SB, Vogelstein B, et al. The rapid and highly parallel identification of antibodies with defined biological activities by SLISY. Nature Communications. 14: 17. PMID 36596784 DOI: 10.1038/s41467-022-35668-6 |
0.789 |
|
| 2022 |
Aytenfisu TY, Campbell HM, Chakrabarti M, Amzel LM, Gabelli SB. Class I PI3K Biology. Current Topics in Microbiology and Immunology. 436: 3-49. PMID 36243838 DOI: 10.1007/978-3-031-06566-8_1 |
0.796 |
|
| 2022 |
Sengupta S, Board NL, Wu F, Moskovljevic M, Douglass J, Zhang J, Reinhold BR, Duke-Cohan J, Yu J, Reed MC, Tabdili Y, Azurmendi A, Fray EJ, Zhang H, Hsiue EH, ... ... Gabelli SB, et al. TCR-mimic bispecific antibodies to target the HIV-1 reservoir. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123406119. PMID 35394875 DOI: 10.1073/pnas.2123406119 |
0.587 |
|
| 2022 |
Jiang H, Chiang CY, Chen Z, Nathan S, D'Agostino G, Paulo JA, Song G, Zhu H, Gabelli SB, Cole PA. Enzymatic Analysis of WWP2 E3 Ubiquitin Ligase Using Protein Microarrays Identifies Autophagy-Related Substrates. The Journal of Biological Chemistry. 101854. PMID 35331737 DOI: 10.1016/j.jbc.2022.101854 |
0.488 |
|
| 2022 |
Nguyen T, Phan KL, Kozakov D, Gabelli SB, Kreitler DF, Andrews LC, Jakoncic J, Sweet RM, Soares AS, Bernstein HJ. A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs. Acta Crystallographica. Section D, Structural Biology. 78: 268-277. PMID 35234141 DOI: 10.1107/S2059798321013425 |
0.712 |
|
| 2022 |
Srinivasan L, Alzogaray V, Selvakumar D, Nathan S, Yoder JB, Wright KM, Klinke S, Nwafor JN, Labanda MS, Goldbaum FA, Schön A, Freire E, Tomaselli GF, Amzel LM, Ben-Johny M, ... Gabelli SB, et al. Development of High affinity Nanobodies Specific for Na1.4 and Na1.5 Voltage-Gated Sodium Channel Isoforms. The Journal of Biological Chemistry. 101763. PMID 35202650 DOI: 10.1016/j.jbc.2022.101763 |
0.771 |
|
| 2022 |
Pearlman AH, Hwang MS, Konig MF, Hsiue EH, Douglass J, DiNapoli SR, Mog BJ, Bettegowda C, Pardoll DM, Gabelli SB, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Author Correction: Targeting public neoantigens for cancer immunotherapy. Nature Cancer. 2: 865-867. PMID 35122030 DOI: 10.1038/s43018-021-00246-0 |
0.654 |
|
| 2021 |
Salguero AL, Chen M, Balana AT, Chu N, Jiang H, Palanski BA, Bae H, Wright KM, Nathan S, Zhu H, Gabelli SB, Pratt MR, Cole PA. Multifaceted Regulation of Akt by Diverse C-Terminal Post-translational Modifications. Acs Chemical Biology. PMID 34941261 DOI: 10.1021/acschembio.1c00632 |
0.75 |
|
| 2021 |
Ma Q, Srinivasan L, Gabelli SB, Raben DM. Elusive structure of mammalian DGKs. Advances in Biological Regulation. 100847. PMID 34922895 DOI: 10.1016/j.jbior.2021.100847 |
0.654 |
|
| 2021 |
Pearlman AH, Hwang MS, Konig MF, Hsiue EH, Douglass J, DiNapoli SR, Mog BJ, Bettegowda C, Pardoll DM, Gabelli SB, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Targeting public neoantigens for cancer immunotherapy. Nature Cancer. 2: 487-497. PMID 34676374 DOI: 10.1038/s43018-021-00210-y |
0.681 |
|
| 2021 |
Dempsey DR, Viennet T, Iwase R, Park E, Henriquez S, Chen Z, Jeliazkov JR, Palanski BA, Phan KL, Coote P, Gray JJ, Eck MJ, Gabelli SB, Arthanari H, Cole PA. The structural basis of PTEN regulation by multi-site phosphorylation. Nature Structural & Molecular Biology. 28: 858-868. PMID 34625746 DOI: 10.1038/s41594-021-00668-5 |
0.783 |
|
| 2021 |
Hwang MS, Miller MS, Thirawatananond P, Douglass J, Wright KM, Hsiue EH, Mog BJ, Aytenfisu TY, Murphy MB, Aitana Azurmendi P, Skora AD, Pearlman AH, Paul S, DiNapoli SR, Konig MF, ... ... Gabelli SB, et al. Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens. Nature Communications. 12: 5271. PMID 34489470 DOI: 10.1038/s41467-021-25605-4 |
0.773 |
|
| 2021 |
Hwang MS, Mog BJ, Douglass J, Pearlman AH, Hsiue EH, Paul S, DiNapoli SR, Konig MF, Pardoll DM, Gabelli SB, Bettegowda C, Papadopoulos N, Vogelstein B, Zhou S, Kinzler KW. Targeting loss of heterozygosity for cancer-specific immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33731480 DOI: 10.1073/pnas.2022410118 |
0.68 |
|
| 2021 |
Paul S, Pearlman AH, Douglass J, Mog BJ, Hsiue EH, Hwang MS, DiNapoli SR, Konig MF, Brown PA, Wright KM, Sur S, Gabelli SB, Li Y, Ghiaur G, Pardoll D, et al. TCR beta chain-directed bispecific antibodies for the treatment of T-cell cancers. Science Translational Medicine. PMID 33649188 DOI: 10.1126/scitranslmed.abd3595 |
0.764 |
|
| 2021 |
Hsiue EH, Wright KM, Douglass J, Hwang MS, Mog BJ, Pearlman AH, Paul S, DiNapoli SR, Konig MF, Wang Q, Schaefer A, Miller MS, Skora AD, Azurmendi PA, Murphy MB, ... ... Gabelli SB, et al. Targeting a neoantigen derived from a common mutation. Science (New York, N.Y.). PMID 33649166 DOI: 10.1126/science.abc8697 |
0.789 |
|
| 2021 |
Douglass J, Hsiue EH, Mog BJ, Hwang MS, DiNapoli SR, Pearlman AH, Miller MS, Wright KM, Azurmendi PA, Wang Q, Paul S, Schaefer A, Skora AD, Molin MD, Konig MF, ... ... Gabelli SB, et al. Bispecific antibodies targeting mutant neoantigens. Science Immunology. 6. PMID 33649101 DOI: 10.1126/sciimmunol.abd5515 |
0.787 |
|
| 2021 |
Nathan S, Gabelli SB, Yoder JB, Srinivasan L, Aldrich RW, Tomaselli GF, Ben-Johny M, Amzel LM. Structural basis of cytoplasmic NaV1.5 and NaV1.4 regulation. The Journal of General Physiology. 153. PMID 33306788 DOI: 10.1085/jgp.202012722 |
0.79 |
|
| 2020 |
Maheshwari S, Kim YS, Aripirala S, Murphy M, Amzel LM, Gabelli SB. Identifying structural determinants of product specificity in Leishmania major farnesyl diphosphate synthase. Biochemistry. PMID 32584028 DOI: 10.1021/Acs.Biochem.0C00432 |
0.791 |
|
| 2020 |
Chang TH, Hsieh FL, Smallwood PM, Gabelli SB, Nathans J. Structure of the RECK CC domain, an evolutionary anomaly. Proceedings of the National Academy of Sciences of the United States of America. PMID 32541044 DOI: 10.1073/Pnas.2006332117 |
0.35 |
|
| 2020 |
Branco Santos JC, de Melo JA, Maheshwari S, de Medeiros WMTQ, de Freitas Oliveira JW, Moreno CJ, Mario Amzel L, Gabelli SB, Sousa Silva M. Bisphosphonate-Based Molecules as Potential New Antiparasitic Drugs. Molecules (Basel, Switzerland). 25. PMID 32503272 DOI: 10.3390/Molecules25112602 |
0.765 |
|
| 2020 |
Chakrabarti M, Gabelli SB, Amzel LM. Allosteric Activation of PI3Kα Results in Dynamic Access to Catalytically Competent Conformations. Structure (London, England : 1993). PMID 32049032 DOI: 10.1016/J.Str.2020.01.010 |
0.704 |
|
| 2019 |
Miller MS, Douglass J, Hwang MS, Skora AD, Murphy M, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S, Gabelli SB. An engineered antibody fragment targeting mutant β-catenin via Major Histocompatibility Complex I neoantigen presentation. The Journal of Biological Chemistry. PMID 31690625 DOI: 10.1074/Jbc.Ra119.010251 |
0.737 |
|
| 2019 |
Thirawatananond P, McPherson RL, Malhi J, Nathan S, Lambrecht MJ, Brichacek M, Hergenrother PJ, Leung AKL, Gabelli SB. Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins. Scientific Reports. 9: 5940. PMID 30976021 DOI: 10.2210/Pdb6B09/Pdb |
0.812 |
|
| 2019 |
Yoder JB, Ben-Johny M, Farinelli F, Srinivasan L, Shoemaker SR, Tomaselli GF, Gabelli SB, Amzel LM. Ca-dependent regulation of sodium channels Na1.4 and Na1.5 is controlled by the post-IQ motif. Nature Communications. 10: 1514. PMID 30944319 DOI: 10.1038/S41467-019-09570-7 |
0.795 |
|
| 2019 |
Miller MS, Thompson PE, Gabelli SB. Structural Determinants of Isoform Selectivity in PI3K Inhibitors. Biomolecules. 9. PMID 30813656 DOI: 10.3390/biom9030082 |
0.506 |
|
| 2019 |
Miller MS, Maheshwari S, Shi W, Gao Y, Chu N, Soares AS, Cole PA, Amzel LM, Fuchs MR, Jakoncic J, Gabelli SB. Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II. Molecules (Basel, Switzerland). 24. PMID 30704096 DOI: 10.3390/Molecules24030496 |
0.759 |
|
| 2019 |
Nathan S, Shoemaker S, Farinelli F, Yoder J, Amzel LM, Tomaselli GF, Gabelli SB. An Attempted Molecular Rescue of an Arrhythmogenic Cardiac Disease Mutation Biophysical Journal. 116: 387a. DOI: 10.1016/J.Bpj.2018.11.2097 |
0.699 |
|
| 2018 |
Ma Q, Gabelli SB, Raben DM. Diacylglycerol kinases: Relationship to other lipid kinases. Advances in Biological Regulation. PMID 30348515 DOI: 10.1016/J.Jbior.2018.09.014 |
0.346 |
|
| 2018 |
Maheshwari S, Shimokawa C, Rudzka K, Kline CD, Eipper BA, Mains RE, Gabelli SB, Blackburn N, Amzel LM. Effects of copper occupancy on the conformational landscape of peptidylglycine α-hydroxylating monooxygenase. Communications Biology. 1: 74. PMID 30271955 DOI: 10.1038/s42003-018-0082-y |
0.79 |
|
| 2018 |
Chu N, Salguero AL, Liu AZ, Chen Z, Dempsey DR, Ficarro SB, Alexander WM, Marto JA, Li Y, Amzel LM, Gabelli SB, Cole PA. Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis. Cell. PMID 30078705 DOI: 10.1016/J.Cell.2018.07.003 |
0.732 |
|
| 2018 |
Banerjee R, Yoder JB, Yue DT, Amzel LM, Tomaselli GF, Gabelli SB, Ben-Johny M. Bilobal architecture is a requirement for calmodulin signaling to Ca1.3 channels. Proceedings of the National Academy of Sciences of the United States of America. PMID 29531055 DOI: 10.1073/Pnas.1716381115 |
0.704 |
|
| 2018 |
Shumar SA, Kerr EW, Geldenhuys WJ, Montgomery GE, Fagone P, Thirawatananond P, Saavedra H, Gabelli SB, Leonardi R. Nudt19 is a renal CoA diphosphohydrolase with biochemical and regulatory properties that are distinct from the hepatic Nudt7 isoform. The Journal of Biological Chemistry. PMID 29378847 DOI: 10.1074/Jbc.Ra117.001358 |
0.793 |
|
| 2017 |
Nakamura H, Lee AA, Afshar AS, Watanabe S, Rho E, Razavi S, Suarez A, Lin YC, Tanigawa M, Huang B, DeRose R, Bobb D, Hong W, Gabelli SB, Goutsias J, et al. Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions. Nature Materials. PMID 29115293 DOI: 10.1038/Nmat5006 |
0.774 |
|
| 2017 |
Chatterjee S, Lesniak WG, Miller MS, Lisok A, Sikorska E, Wharram B, Kumar D, Gabrielson M, Pomper MG, Gabelli SB, Nimmagadda S. Corrigendum to "Rapid PD-L1 detection in tumors with PET using a highly specific peptide" [Biochemical and Biophysical Research Communications 483/1 (2017) 258-263]. Biochemical and Biophysical Research Communications. PMID 28801167 DOI: 10.1016/J.Bbrc.2017.08.001 |
0.438 |
|
| 2017 |
Maheshwari S, Miller MS, O'Meally R, Cole RN, Amzel LM, Gabelli SB. Kinetic and structural analyses reveal residues in phosphoinositide 3-kinase α that are critical for catalysis and substrate recognition. The Journal of Biological Chemistry. PMID 28676499 DOI: 10.1074/Jbc.M116.772426 |
0.806 |
|
| 2017 |
Sarker R, Cha B, Kovbasnjuk O, Cole R, Gabelli S, Tse CM, Donowitz M. Phosphorylation of NHE3-S(719) Regulates NHE3 Activity through the Formation of Multiple Signaling Complexes. Molecular Biology of the Cell. PMID 28495796 DOI: 10.1091/Mbc.E16-12-0862 |
0.384 |
|
| 2017 |
Chen Z, Jiang H, Xu W, Li X, Dempsey DR, Zhang X, Devreotes P, Wolberger C, Amzel LM, Gabelli SB, Cole PA. A Tunable Brake for HECT Ubiquitin Ligases. Molecular Cell. 66: 345-357.e6. PMID 28475870 DOI: 10.1016/J.Molcel.2017.03.020 |
0.738 |
|
| 2017 |
Miller MS, Maheshwari S, McRobb FM, Kinzler KW, Amzel LM, Vogelstein B, Gabelli SB. Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design. Bioorganic & Medicinal Chemistry. PMID 28129991 DOI: 10.1016/J.Bmc.2017.01.012 |
0.803 |
|
| 2017 |
Thirawatananond P, McPherson RL, Malhi JK, Leung AK, Gabelli SB. Abstract 2212: Protein engineering of the decapping enzyme NudT16 enhances its ability to hydrolyze protein-conjugated ADP-ribose for post-translational site identification via mass spectrometry Cancer Research. 77: 2212-2212. DOI: 10.1158/1538-7445.Am2017-2212 |
0.805 |
|
| 2017 |
Gabelli SB, Chen Z, Jiang H, Dempsey D, Amzel LM, Wolberger C, Devreotes P, Cole P. Regulation of WWP2 ubiquitin ligase Acta Crystallographica Section a Foundations and Advances. 73: C833-C833. DOI: 10.1107/S2053273317087411 |
0.633 |
|
| 2017 |
Yoder JB, Gabelli SB, Amzel LM. Investigating Ca 2+ -Dependent Regulation of Sodium Channels via Thermodynamic and Structural Analysis of Nav1.4 and Nav1.5 Carboxy Tail Interactions with Calmodulin Biophysical Journal. 112: 19a. DOI: 10.1016/J.Bpj.2016.11.137 |
0.652 |
|
| 2016 |
Chatterjee S, Lesniak WG, Miller MS, Lisok A, Sikorska E, Wharram B, Kumar D, Gabrielson M, Pomper MG, Gabelli SB, Nimmagadda S. Rapid PD-L1 detection in tumors with PET using a highly specific peptide. Biochemical and Biophysical Research Communications. PMID 28025143 DOI: 10.1016/J.Bbrc.2016.12.156 |
0.446 |
|
| 2016 |
O'Handley SF, Thirawatananond P, Kang LW, Cunningham JE, Leyva JA, Amzel LM, Gabelli SB. Kinetic and mutational studies of the adenosine diphosphate ribose hydrolase from Mycobacterium tuberculosis. Journal of Bioenergetics and Biomembranes. PMID 27683242 DOI: 10.1007/S10863-016-9681-9 |
0.79 |
|
| 2015 |
Daniels CM, Thirawatananond P, Ong SE, Gabelli SB, Leung AK. Nudix hydrolases degrade protein-conjugated ADP-ribose. Scientific Reports. 5: 18271. PMID 26669448 DOI: 10.1038/Srep18271 |
0.8 |
|
| 2015 |
de la Peña AH, Suarez A, Duong-Ly KC, Schoeffield AJ, Pizarro-Dupuy MA, Zarr M, Pineiro SA, Amzel LM, Gabelli SB. Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus. Plos One. 10: e0141716. PMID 26524597 DOI: 10.1371/Journal.Pone.0141716 |
0.798 |
|
| 2015 |
Gabelli SB, Yoder JB, Tomaselli GF, Amzel LM. Calmodulin and Ca(2+) control of voltage gated Na(+) channels. Channels (Austin, Tex.). 0. PMID 26218606 DOI: 10.1080/19336950.2015.1075677 |
0.721 |
|
| 2015 |
Skora AD, Douglass J, Hwang MS, Tam AJ, Blosser RL, Gabelli SB, Cao J, Diaz LA, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Generation of MANAbodies specific to HLA-restricted epitopes encoded by somatically mutated genes. Proceedings of the National Academy of Sciences of the United States of America. PMID 26216968 DOI: 10.1073/Pnas.1511996112 |
0.652 |
|
| 2015 |
Echeverria I, Liu Y, Gabelli SB, Amzel LM. Oncogenic mutations weaken the interactions that stabilize the p110α-p85α heterodimer in phosphatidylinositol 3-kinase α. The Febs Journal. 282: 3528-42. PMID 26122737 DOI: 10.1111/Febs.13365 |
0.703 |
|
| 2015 |
Duong-Ly KC, Gabelli SB. Affinity Purification of a Recombinant Protein Expressed as a Fusion with the Maltose-Binding Protein (MBP) Tag. Methods in Enzymology. 559: 17-26. PMID 26096500 DOI: 10.1016/Bs.Mie.2014.11.004 |
0.781 |
|
| 2015 |
Wolff KA, de la Peña AH, Nguyen HT, Pham TH, Amzel LM, Gabelli SB, Nguyen L. A redox regulatory system critical for mycobacterial survival in macrophages and biofilm development. Plos Pathogens. 11: e1004839. PMID 25884716 DOI: 10.1371/Journal.Ppat.1004839 |
0.651 |
|
| 2015 |
Wolff KA, Peña AHdl, Nguyen HT, Pham TH, Amzel LM, Gabelli SB, Nguyen L. L13, a ribosomal protein associated with RenU, is phosphorylated by PknG. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1004839.G004 |
0.633 |
|
| 2015 |
Wolff KA, Peña AHdl, Nguyen HT, Pham TH, Amzel LM, Gabelli SB, Nguyen L. Both pknG and its adjacent gene renU are each required for oxidative stress resistance. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1004839.G002 |
0.598 |
|
| 2015 |
Miller M, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Abstract PR02: Targeting PI3K: The PIP2 binding site Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Pi3K14-Pr02 |
0.819 |
|
| 2015 |
Gabelli SB, Boto A, Halpernin V, Bianchet MA, Farinelli F, Aripirala S, Yoder JB, Jakoncic J, Tomaselli GF, Amzel M. Cardiac Sodium Channel: Activation by CaM Involves a NaV1.5-NaV1.5 Interaction Biophysical Journal. 108: 127a-128a. DOI: 10.1016/J.Bpj.2014.11.712 |
0.779 |
|
| 2015 |
Wolff KA, de la Peña AH, Nguyen HT, Amzel LM, Gabelli SB, Nguyen L. A Nudix Hydrolase Necessary for Mycobacterium Tuberculosis Survival under Oxidative Stress Biophysical Journal. 108: 533a. DOI: 10.1016/J.Bpj.2014.11.2924 |
0.614 |
|
| 2014 |
Gabelli SB, Boto A, Kuhns VH, Bianchet MA, Farinelli F, Aripirala S, Yoder J, Jakoncic J, Tomaselli GF, Amzel LM. Regulation of the NaV1.5 cytoplasmic domain by calmodulin. Nature Communications. 5: 5126. PMID 25370050 DOI: 10.1038/Ncomms6126 |
0.787 |
|
| 2014 |
Gabelli SB, Echeverria I, Alexander M, Duong-Ly KC, Chaves-Moreira D, Brower ET, Vogelstein B, Amzel LM. Activation of PI3Kα by physiological effectors and by oncogenic mutations: structural and dynamic effects. Biophysical Reviews. 6: 89-95. PMID 25309634 DOI: 10.1007/S12551-013-0131-1 |
0.812 |
|
| 2014 |
Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Structural basis of nSH2 regulation and lipid binding in PI3Kα. Oncotarget. 5: 5198-208. PMID 25105564 DOI: 10.18632/Oncotarget.2263 |
0.821 |
|
| 2014 |
Duong-Ly KC, Gabelli SB. Explanatory chapter: troubleshooting protein expression: what to do when the protein is not soluble. Methods in Enzymology. 541: 231-47. PMID 24674075 DOI: 10.1016/B978-0-12-420119-4.00018-5 |
0.775 |
|
| 2014 |
Duong-Ly KC, Gabelli SB. Explanatory chapter: troubleshooting recombinant protein expression: general. Methods in Enzymology. 541: 209-29. PMID 24674074 DOI: 10.1016/B978-0-12-420119-4.00017-3 |
0.769 |
|
| 2014 |
Duong-Ly KC, Gabelli SB. Gel filtration chromatography (size exclusion chromatography) of proteins. Methods in Enzymology. 541: 105-14. PMID 24674066 DOI: 10.1016/B978-0-12-420119-4.00009-4 |
0.766 |
|
| 2014 |
Duong-Ly KC, Gabelli SB. Using ion exchange chromatography to purify a recombinantly expressed protein. Methods in Enzymology. 541: 95-103. PMID 24674065 DOI: 10.1016/B978-0-12-420119-4.00008-2 |
0.783 |
|
| 2014 |
Duong-Ly KC, Gabelli SB. Salting out of proteins using ammonium sulfate precipitation. Methods in Enzymology. 541: 85-94. PMID 24674064 DOI: 10.1016/B978-0-12-420119-4.00007-0 |
0.776 |
|
| 2014 |
Aripirala S, Gonzalez-Pacanowska D, Oldfield E, Kaiser M, Amzel LM, Gabelli SB. Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates. Acta Crystallographica. Section D, Biological Crystallography. 70: 802-10. PMID 24598749 DOI: 10.1107/S1399004713033221 |
0.809 |
|
| 2014 |
Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Abstract LB-326: Structural basis of lipid-binding and regulation in PI3Kα Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-326 |
0.821 |
|
| 2014 |
Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Structural basis of nSH2 regulation and lipid binding in PI3Kα Oncotarget. 5: 5198-5208. |
0.788 |
|
| 2013 |
Bolduc D, Rahdar M, Tu-Sekine B, Sivakumaren SC, Raben D, Amzel LM, Devreotes P, Gabelli SB, Cole P. Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis. Elife. 2: e00691. PMID 23853711 DOI: 10.7554/Elife.00691 |
0.734 |
|
| 2013 |
Duong-Ly KC, Woo HN, Dunn CA, Xu W, Babič A, Bessman MJ, Amzel LM, Gabelli SB. A UDP-X diphosphatase from Streptococcus pneumoniae hydrolyzes precursors of peptidoglycan biosynthesis. Plos One. 8: e64241. PMID 23691178 DOI: 10.1371/Journal.Pone.0064241 |
0.802 |
|
| 2013 |
Zhang F, Bhat S, Gabelli SB, Chen X, Miller MS, Nacev BA, Cheng YL, Meyers DJ, Tenney K, Shim JS, Crews P, Amzel LM, Ma D, Liu JO. Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells Journal of Medicinal Chemistry. 56: 3996-4016. PMID 23634668 DOI: 10.1021/Jm400227Z |
0.709 |
|
| 2013 |
Zhang P, Yang X, Zhang F, Gabelli SB, Wang R, Zhang Y, Bhat S, Chen X, Furlani M, Amzel LM, Liu JO, Ma D. Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase-1. Bioorganic & Medicinal Chemistry. 21: 2600-17. PMID 23507151 DOI: 10.1016/J.Bmc.2013.02.023 |
0.669 |
|
| 2013 |
Bolduc D, Rahdar M, Tu-Sekine B, Sivakumaren SC, Raben D, Amzel LM, Devreotes P, Gabelli SB, Cole P. Author response: Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis Elife. DOI: 10.7554/Elife.00691.027 |
0.701 |
|
| 2013 |
Brower ET, Gabelli SB, Wang Q, Chaerkady R, Berndsen CE, Cole RN, Backer JM, Schäfer M, Sinz A, Kinzler KW, Vogelstein B, Amzel LM. Abstract 2225: The molecular architecture of p85α as determined by SAXS and chemical cross-linking. Cancer Research. 73: 2225-2225. DOI: 10.1158/1538-7445.Am2013-2225 |
0.776 |
|
| 2012 |
Aripirala S, Szajnman SH, Jakoncic J, Rodriguez JB, Docampo R, Gabelli SB, Amzel LM. Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase. Journal of Medicinal Chemistry. 55: 6445-54. PMID 22715997 DOI: 10.1021/Jm300425Y |
0.791 |
|
| 2011 |
Boto AN, Xu W, Jakoncic J, Pannuri A, Romeo T, Bessman MJ, Gabelli SB, Amzel LM. Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition. Proteins. 79: 2455-66. PMID 21638333 DOI: 10.1002/Prot.23069 |
0.803 |
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| 2011 |
Duong-Ly KC, Gabelli SB, Xu W, Dunn CA, Schoeffield AJ, Bessman MJ, Amzel LM. The Nudix hydrolase CDP-chase, a CDP-choline pyrophosphatase, is an asymmetric dimer with two distinct enzymatic activities. Journal of Bacteriology. 193: 3175-85. PMID 21531795 DOI: 10.1128/Jb.00089-11 |
0.801 |
|
| 2011 |
Gabelli SB, Duong-Ly KC, Brower ET, Amzel LM. Capitalizing on tumor genotyping: towards the design of mutation specific inhibitors of phosphoinsitide-3-kinase. Advances in Enzyme Regulation. 51: 273-9. PMID 21035489 DOI: 10.1016/J.Advenzreg.2010.09.013 |
0.821 |
|
| 2011 |
Aripirala S, Gabelli S, Oldfield E, Pacanowska DG, Amzel M. Inhibitors of Leishmania Major Farnesyl Diphosphate Synthase: Crystallographic and Calorimetric Studies Biophysical Journal. 100: 218a-219a. DOI: 10.1016/J.Bpj.2010.12.1406 |
0.793 |
|
| 2011 |
Duong-Ly KC, Gabelli SB, Xu W, Dunn CA, Bessman MJ, Amzel LM. CDP-Chase, a CDP-Choline Pyrophosphatase, is a Member of a Novel Nudix Family in Gram-Positive Bacteria Biophysical Journal. 100: 218a. DOI: 10.1016/J.Bpj.2010.12.1402 |
0.807 |
|
| 2010 |
Schmidt-Kittler O, Zhu J, Yang J, Liu G, Hendricks W, Lengauer C, Gabelli SB, Kinzler KW, Vogelstein B, Huso DL, Zhou S. PI3Kα inhibitors that inhibit metastasis. Oncotarget. 1: 339-348. PMID 21179398 DOI: 10.18632/Oncotarget.166 |
0.777 |
|
| 2010 |
Messing SA, Gabelli SB, Echeverria I, Vogel JT, Guan JC, Tan BC, Klee HJ, McCarty DR, Amzel LM. Structural insights into maize viviparous14, a key enzyme in the biosynthesis of the phytohormone abscisic acid. The Plant Cell. 22: 2970-80. PMID 20884803 DOI: 10.1105/Tpc.110.074815 |
0.795 |
|
| 2010 |
Mohan S, Tse CM, Gabelli SB, Sarker R, Cha B, Fahie K, Nadella M, Zachos NC, Tu-Sekine B, Raben D, Amzel LM, Donowitz M. NHE3 activity is dependent on direct phosphoinositide binding at the N terminus of its intracellular cytosolic region. The Journal of Biological Chemistry. 285: 34566-78. PMID 20736165 DOI: 10.1074/Jbc.M110.165712 |
0.79 |
|
| 2010 |
Gabelli SB, Huang CH, Mandelker D, Schmidt-Kittler O, Vogelstein B, Amzel LM. Structural effects of oncogenic PI3Kα mutations Current Topics in Microbiology and Immunology. 347: 43-53. PMID 20593314 DOI: 10.1007/82_2010_53 |
0.815 |
|
| 2010 |
Barrila J, Gabelli SB, Bacha U, Amzel LM, Freire E. Mutation of Asn28 disrupts the dimerization and enzymatic activity of SARS 3CL(pro) . Biochemistry. 49: 4308-17. PMID 20420403 DOI: 10.1021/Bi1002585 |
0.712 |
|
| 2010 |
Gabelli SB, Mandelker D, Schmidt-Kittler O, Vogelstein B, Amzel LM. Somatic mutations in PI3Kα: Structural basis for enzyme activation and drug design Biochimica Et Biophysica Acta - Proteins and Proteomics. 1804: 533-540. PMID 19962457 DOI: 10.1016/J.Bbapap.2009.11.020 |
0.801 |
|
| 2010 |
Huang CH, Gabelli SB, Oldfield E, Amzel LM. Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer. Proteins. 78: 888-99. PMID 19876942 DOI: 10.1002/Prot.22614 |
0.776 |
|
| 2009 |
Mandelker D, Gabelli SB, Schmidt-Kittler O, Zhu J, Cheong I, Huang CH, Kinzler KW, Vogelstein B, Amzel LM. A frequent kinase domain mutation that changes the interaction between PI3Kα and the membrane Proceedings of the National Academy of Sciences of the United States of America. 106: 16996-17001. PMID 19805105 DOI: 10.1073/Pnas.0908444106 |
0.813 |
|
| 2009 |
Messing SA, Gabelli SB, Liu Q, Celesnik H, Belasco JG, Piñeiro SA, Amzel LM. Structure and biological function of the RNA pyrophosphohydrolase BdRppH from Bdellovibrio bacteriovorus. Structure (London, England : 1993). 17: 472-81. PMID 19278661 DOI: 10.1016/J.Str.2008.12.022 |
0.789 |
|
| 2008 |
Steyert SR, Messing SA, Amzel LM, Gabelli SB, Piñeiro SA. Identification of Bdellovibrio bacteriovorus HD100 Bd0714 as a Nudix dGTPase. Journal of Bacteriology. 190: 8215-9. PMID 18931106 DOI: 10.1128/Jb.01009-08 |
0.769 |
|
| 2008 |
Amzel LM, Huang CH, Mandelker D, Lengauer C, Gabelli SB, Vogelstein B. Structural comparisons of class I phosphoinositide 3-kinases Nature Reviews Cancer. 8: 665-669. PMID 18633356 DOI: 10.1038/Nrc2443 |
0.805 |
|
| 2008 |
Bacha U, Barrila J, Gabelli SB, Kiso Y, Mario Amzel L, Freire E. Development of broad-spectrum halomethyl ketone inhibitors against coronavirus main protease 3CL(pro). Chemical Biology & Drug Design. 72: 34-49. PMID 18611220 DOI: 10.1111/J.1747-0285.2008.00679.X |
0.348 |
|
| 2008 |
Huang CH, Mandelker D, Gabelli SB, Amzel LM. Insights into the oncogenic effects of PIK3CA mutations from the structure of p110alpha/p85alpha. Cell Cycle (Georgetown, Tex.). 7: 1151-6. PMID 18418043 DOI: 10.4161/Cc.7.9.5817 |
0.81 |
|
| 2008 |
Gabelli S, Huang C, Mandelker D, Vogelstein B, Amzel L. Structural basis for the effects of PI3Kalpha oncogenic mutations Acta Crystallographica Section a Foundations of Crystallography. 64: C79-C80. DOI: 10.1107/S0108767308097456 |
0.789 |
|
| 2007 |
Huang CH, Mandelker D, Schmidt-Kittler O, Samuels Y, Velculescu VE, Kinzler KW, Vogelstein B, Gabelli SB, Amzel LM. The structure of a human p110α/p85α complex elucidates the effects of oncogenic PI3Kα mutations Science. 318: 1744-1748. PMID 18079394 DOI: 10.1126/Science.1150799 |
0.821 |
|
| 2007 |
Gabelli SB, Bianchet MA, Xu W, Dunn CA, Niu ZD, Amzel LM, Bessman MJ. Structure and function of the E. coli dihydroneopterin triphosphate pyrophosphatase: a Nudix enzyme involved in folate biosynthesis. Structure (London, England : 1993). 15: 1014-22. PMID 17698004 DOI: 10.1016/J.Str.2007.06.018 |
0.765 |
|
| 2006 |
Gabelli SB, Azurmendi HF, Bianchet MA, Amzel LM, Mildvan AS. X-ray, NMR, and mutational studies of the catalytic cycle of the GDP-mannose mannosyl hydrolase reaction. Biochemistry. 45: 11290-303. PMID 16981689 DOI: 10.1021/Bi061239G |
0.701 |
|
| 2006 |
Gabelli SB, McLellan JS, Montalvetti A, Oldfield E, Docampo R, Amzel LM. Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: implications for drug design. Proteins. 62: 80-8. PMID 16288456 DOI: 10.1002/Prot.20754 |
0.783 |
|
| 2006 |
Mildvan AS, Xia Z, Azurmendi HF, Legler PM, Balfour MR, Lairson LL, Withers SG, Gabelli SB, Bianchet MA, Amzel LM. Hydrogen bonding in the mechanism of GDP-mannose mannosyl hydrolase Journal of Molecular Structure. 790: 160-167. DOI: 10.1016/J.Molstruc.2005.09.024 |
0.666 |
|
| 2005 |
Nadella M, Bianchet MA, Gabelli SB, Barrila J, Amzel LM. Structure and activity of the axon guidance protein MICAL. Proceedings of the National Academy of Sciences of the United States of America. 102: 16830-5. PMID 16275926 DOI: 10.1073/Pnas.0504838102 |
0.783 |
|
| 2005 |
Coblitz B, Shikano S, Wu M, Gabelli SB, Cockrell LM, Spieker M, Hanyu Y, Fu H, Amzel LM, Li M. C-terminal recognition by 14-3-3 proteins for surface expression of membrane receptors. The Journal of Biological Chemistry. 280: 36263-72. PMID 16123035 DOI: 10.1074/Jbc.M507559200 |
0.673 |
|
| 2005 |
Xia Z, Azurmendi HF, Lairson LL, Withers SG, Gabelli SB, Bianchet MA, Amzel LM, Mildvan AS. Mutational, structural, and kinetic evidence for a dissociative mechanism in the GDP-mannose mannosyl hydrolase reaction. Biochemistry. 44: 8989-97. PMID 15966723 DOI: 10.1021/Bi050583V |
0.664 |
|
| 2005 |
Mildvan AS, Xia Z, Azurmendi HF, Saraswat V, Legler PM, Massiah MA, Gabelli SB, Bianchet MA, Kang LW, Amzel LM. Structures and mechanisms of Nudix hydrolases. Archives of Biochemistry and Biophysics. 433: 129-43. PMID 15581572 DOI: 10.1016/J.Abb.2004.08.017 |
0.738 |
|
| 2005 |
Gabelli SB, McLellan JS, Montalvetti A, Oldfield E, Docampo R, Amzel LM. The mechanism ofT. cruziFPPS involves a substrate induced conformational change Acta Crystallographica Section a Foundations of Crystallography. 61: c197-c197. DOI: 10.1107/S0108767305091610 |
0.737 |
|
| 2004 |
Gabelli SB, Bianchet MA, Azurmendi HF, Xia Z, Sarawat V, Mildvan AS, Amzel LM. Structure and mechanism of GDP-mannose glycosyl hydrolase, a Nudix enzyme that cleaves at carbon instead of phosphorus. Structure (London, England : 1993). 12: 927-35. PMID 15274914 DOI: 10.1016/J.Str.2004.03.028 |
0.698 |
|
| 2003 |
Kang LW, Gabelli SB, Cunningham JE, O'Handley SF, Amzel LM. Structure and mechanism of MT-ADPRase, a nudix hydrolase from Mycobacterium tuberculosis. Structure (London, England : 1993). 11: 1015-23. PMID 12906832 DOI: 10.1016/S0969-2126(03)00154-0 |
0.8 |
|
| 2003 |
Kang LW, Gabelli SB, Bianchet MA, Xu WL, Bessman MJ, Amzel LM. Structure of a coenzyme A pyrophosphatase from Deinococcus radiodurans: a member of the Nudix family. Journal of Bacteriology. 185: 4110-8. PMID 12837785 DOI: 10.1128/Jb.185.14.4110-4118.2003 |
0.812 |
|
| 2003 |
Cho HS, Mason K, Ramyar KX, Stanley AM, Gabelli SB, Denney DW, Leahy DJ. Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab. Nature. 421: 756-60. PMID 12610629 DOI: 10.1038/Nature01392 |
0.313 |
|
| 2002 |
Gabelli SB, Bianchet MA, Ohnishi Y, Ichikawa Y, Bessman MJ, Amzel LM. Mechanism of the Escherichia coli ADP-ribose pyrophosphatase, a Nudix hydrolase. Biochemistry. 41: 9279-85. PMID 12135348 DOI: 10.1021/Bi0259296 |
0.765 |
|
| 2001 |
Gabelli SB, Bianchet MA, Bessman MJ, Amzel LM. The structure of ADP-ribose pyrophosphatase reveals the structural basis for the versatility of the Nudix family. Nature Structural Biology. 8: 467-72. PMID 11323725 DOI: 10.1038/87647 |
0.789 |
|
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