Jose R. Conejo-Garcia - Publications

Affiliations: 
Immunology and Microbiology Dartmouth College, Hanover, NH, United States 
Area:
Immunology, Molecular Biology, Oncology

171 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Hathaway CA, Townsend MK, Wang T, Vinci C, Jake-Schoffman DE, Hecht JL, Saeed-Vafa D, Moran Segura C, Nguyen JV, Conejo-Garcia JR, Fridley BL, Tworoger SS. Lifetime Exposure to Cigarette Smoke, B Cell Tumor Immune Infiltration, and Immunoglobulin Abundance in Ovarian Tumors. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 38517322 DOI: 10.1158/1055-9965.EPI-23-1142  0.33
2024 Soupir AC, Townsend MK, Hathaway CA, Nguyen J, Segura CM, Saeed-Vafa D, Ospina OE, Peres LC, Conejo-Garcia JR, Terry KL, Tworoger SS, Fridley BL. Impact of spatial clustering of cytotoxic and tumor infiltrating lymphocytes on overall survival in women with high grade serous ovarian cancer. Medrxiv : the Preprint Server For Health Sciences. PMID 38293174 DOI: 10.1101/2024.01.16.24301371  0.365
2023 Hwang SM, Awasthi D, Jeong J, Sandoval TA, Chae CS, Ramos Y, Tan C, Falco MM, McBain IT, Mishra B, Ivashkiv LB, Zamarin D, Cantillo E, Chapman-Davis E, Holcomb K, ... ... Conejo-Garcia JR, et al. Transgelin 2 guards T cell lipid metabolic programming and anti-tumor function. Research Square. PMID 38168227 DOI: 10.21203/rs.3.rs-3683989/v1  0.755
2023 Biswas S, Mandal G, Anadon CM, Chaurio RA, Lopez-Bailon LU, Nagy MZ, Mine JA, Hänggi K, Sprenger KB, Innamarato P, Harro CM, Powers JJ, Johnson J, Fang B, Eysha M, ... ... Conejo-Garcia JR, et al. Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers. Immunity. PMID 37909039 DOI: 10.1016/j.immuni.2023.09.013  0.461
2023 Eljilany I, Saghand PG, Chen J, Ratan A, McCarter M, Carpten J, Colman H, Ikeguchi AP, Puzanov I, Arnold S, Churchman M, Hwu P, Conejo-Garcia J, Dalton WS, Weiner GJ, et al. The T Cell Immunoscore as a Reference for Biomarker Development Utilizing Real-World Data from Patients with Advanced Malignancies Treated with Immune Checkpoint Inhibitors. Cancers. 15. PMID 37894280 DOI: 10.3390/cancers15204913  0.353
2023 Hathaway CA, Townsend MK, Conejo-Garcia JR, Fridley BL, Moran Segura C, Nguyen JV, Armaiz-Pena GN, Sasamoto N, Saeed-Vafa D, Terry KL, Kubzansky LD, Tworoger SS. The relationship of lifetime history of depression on the ovarian tumor immune microenvironment. Brain, Behavior, and Immunity. PMID 37557966 DOI: 10.1016/j.bbi.2023.08.006  0.337
2023 Sasamoto N, Stewart PA, Wang T, Thompson ZJ, Yoder SJ, Hecht JL, Cleveland JL, Conejo-Garcia J, Fridley BL, Terry KL, Tworoger SS. Associations between prediagnostic aspirin use and ovarian tumor gene expression. Cancer Medicine. PMID 37525619 DOI: 10.1002/cam4.6386  0.318
2023 Yang D, Beddows I, Tang H, Cascio S, McGonigal SC, Bai S, Johnson BK, Powers JJ, Acharya R, Bao R, Bruno TC, Soong TR, Conejo-Garcia JR, Shen H, Bility MT, et al. A Novel Humanized Immune Stroma PDX Cancer Model for Therapeutic Studies. Biorxiv : the Preprint Server For Biology. PMID 37461447 DOI: 10.1101/2023.07.03.547206  0.406
2023 Chaudhary R, Slebos RJC, Noel LC, Song F, Poole MI, Hoening DS, Hernandez-Prera JC, Conejo-Garcia JR, Guevara-Patino JA, Wang X, Xie M, Tan AC, Chung CH. EGFR Inhibition by Cetuximab Modulates Hypoxia and IFN Response Genes in Head and Neck Squamous Cell Carcinoma. Cancer Research Communications. 3: 896-907. PMID 37377902 DOI: 10.1158/2767-9764.CRC-22-0443  0.498
2023 Helm EY, Zelenka T, Cismasiu VB, Islam S, Silvane L, Zitti B, Holmes TD, Drashansky TT, Kwiatkowski AJ, Tao C, Dean J, Obermayer AN, Chen X, Keselowsky BG, Zhang W, ... ... Conejo-Garcia JR, et al. Bcl11b sustains multipotency and restricts effector programs of intestinal-resident memory CD8 T cells. Science Immunology. 8: eabn0484. PMID 37115913 DOI: 10.1126/sciimmunol.abn0484  0.306
2023 Hathaway CA, Conejo-Garcia JR, Fridley BL, Rosner B, Saeed-Vafa D, Moran Segura C, Nguyen JV, Hecht JL, Sasamoto N, Terry KL, Tworoger SS, Townsend MK. Measurement of ovarian tumor immune profiles by multiplex immunohistochemistry: implications for epidemiologic studies. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 36940177 DOI: 10.1158/1055-9965.EPI-22-1285  0.466
2023 Bai H, Padron AS, Deng Y, Liao YJ, Murray CJ, Ontiveros C, Kari SJ, Kancharla A, Kornepati AVR, Garcia M, Reyes RM, Gupta HB, Conejo-Garcia JR, Curiel T. Pharmacological tumor PDL1 depletion with chlorambucil treats ovarian cancer and melanoma: improves antitumor immunity and renders anti-PDL1-resistant tumors anti-PDL1-sensitive through NK cell effects. Journal For Immunotherapy of Cancer. 11. PMID 36759012 DOI: 10.1136/jitc-2022-004871  0.496
2022 Tarhini AA, Hanayneh WB, Powers JJ, Segura CMM, Conejo-Garcia JR, Lam CA, Hakam A, Hoffman MS. Case Report: Durable complete pathologic response and organ preservation following ipilimumab and nivolumab for locally advanced primary vaginal mucosal melanoma. Frontiers in Oncology. 12: 1044587. PMID 36531031 DOI: 10.3389/fonc.2022.1044587  0.363
2022 Conejo-Garcia JR, Biswas S, Chaurio R, Rodriguez PC. Neglected no more: B cell-mediated anti-tumor immunity. Seminars in Immunology. 65: 101707. PMID 36527759 DOI: 10.1016/j.smim.2022.101707  0.49
2022 Martin AL, Powell C, Nagy MZ, Innamarato P, Powers J, Nichols D, Anadon CM, Chaurio RA, Kim S, Wang MH, Gong B, Wang X, Scheutz TJ, Antonia SJ, Conejo-Garcia JR, et al. Anti-4-1BB immunotherapy enhances systemic immune effects of radiotherapy to induce B and T cell-dependent anti-tumor immune activation and improve tumor control at unirradiated sites. Cancer Immunology, Immunotherapy : Cii. PMID 36469096 DOI: 10.1007/s00262-022-03325-y  0.579
2022 Hathaway CA, Wang T, Townsend MK, Vinci C, Jake-Schoffman DE, Saeed-Vafa D, Moran Segura C, Nguyen JV, Conejo-Garcia JR, Fridley BL, Tworoger SS. Lifetime Exposure to Cigarette Smoke and Risk of Ovarian Cancer by T Cell Tumor Immune Infiltration. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 36318652 DOI: 10.1158/1055-9965.EPI-22-0877  0.354
2022 Zhang H, Tomar VS, Li J, Basavaraja R, Yan F, Gui J, McBrearty N, Costich TL, Beiting DP, Blanco MA, Nefedova Y, Conejo-Garcia JR, Saggu G, Berger AJ, Gabrilovich DI, et al. Protection of regulatory T cells from fragility and inactivation in the tumor microenvironment. Cancer Immunology Research. PMID 36255418 DOI: 10.1158/2326-6066.CIR-22-0295  0.543
2022 Gupta PK, Allocco JB, Fraipont JM, McKeague ML, Wang P, Andrade MS, McIntosh C, Chen L, Wang Y, Li Y, Andrade J, Conejo-Garcia JR, Chong AS, Alegre ML. Reduced Satb1 expression predisposes CD4 T conventional cells to Treg suppression and promotes transplant survival. Proceedings of the National Academy of Sciences of the United States of America. 119: e2205062119. PMID 36161903 DOI: 10.1073/pnas.2205062119  0.348
2022 Mandula JK, Chang S, Mohamed E, Jimenez R, Sierra-Mondragon RA, Chang DC, Obermayer AN, Moran-Segura CM, Das S, Vazquez-Martinez JA, Prieto K, Chen A, Smalley KSM, Czerniecki B, Forsyth P, ... ... Conejo-Garcia JR, et al. Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses. Cancer Cell. PMID 36150390 DOI: 10.1016/j.ccell.2022.08.016  0.792
2022 Anadon CM, Zhang C, Wang X, Cen L, Conejo-Garcia JR, Yu X. Protocol for the isolation of CD8+ tumor-infiltrating lymphocytes from human tumors and their characterization by single-cell immune profiling and multiome. Star Protocols. 3: 101649. PMID 36065294 DOI: 10.1016/j.xpro.2022.101649  0.509
2022 Conejo-Garcia JR, Guevara-Patino JA. Barriers and Opportunities for CAR T-Cell Targeting of Solid Tumors. Immunological Investigations. 1-11. PMID 35797428 DOI: 10.1080/08820139.2022.2096463  0.467
2022 Conejo-Garcia JR, Innamarato P. γδ T cells share the spotlight in cancer. Nature Cancer. 3: 657-658. PMID 35764741 DOI: 10.1038/s43018-022-00396-9  0.378
2022 Saad M, Lee SJ, Tan AC, El Naqa IM, Hodi FS, Butterfield LH, LaFramboise WA, Storkus W, Karunamurthy AD, Conejo-Garcia J, Hwu P, Streicher H, Sondak VK, Kirkwood JM, Tarhini AA. Enhanced immune activation within the tumor microenvironment and circulation of female high-risk melanoma patients and improved survival with adjuvant CTLA4 blockade compared to males. Journal of Translational Medicine. 20: 253. PMID 35659704 DOI: 10.1186/s12967-022-03450-3  0.381
2022 Murray C, Galvan E, Ontiveros C, Deng Y, Bai H, Padron AS, Hinchee-Rodriguez K, Garcia MG, Kornepati A, Conejo-Garcia J, Curiel TJ. Pharmacologic Tumor PDL1 Depletion with Cefepime or Ceftazidime Promotes DNA Damage and Sensitivity to DNA-Damaging Agents. International Journal of Molecular Sciences. 23. PMID 35563520 DOI: 10.3390/ijms23095129  0.404
2022 Martin AL, Anadon CM, Biswas S, Mine JA, Handley KF, Payne KK, Mandal G, Chaurio RA, Powers JJ, Sprenger KB, Rigolizzo KE, Innamarato P, Harro CM, Mehta S, Perez BA, ... ... Conejo-Garcia JR, et al. Olfactory Receptor OR2H1 is an effective target for CAR T cells in human epithelial tumors. Molecular Cancer Therapeutics. PMID 35499393 DOI: 10.1158/1535-7163.MCT-21-0872  0.479
2022 Anadon CM, Yu X, Hänggi K, Biswas S, Chaurio RA, Martin A, Payne KK, Mandal G, Innamarato P, Harro CM, Mine JA, Sprenger KB, Cortina C, Powers JJ, Costich TL, ... ... Conejo-Garcia JR, et al. Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells. Cancer Cell. PMID 35427494 DOI: 10.1016/j.ccell.2022.03.008  0.534
2022 Song X, Chang S, Seminario-Vidal L, de Mingo Pulido A, Tordesillas L, Song X, Reed RA, Harkins A, Whiddon S, Nguyen JV, Moran Segura C, Zhang C, Yoder S, Sayegh Z, Zhao Y, ... ... Conejo-Garcia JR, et al. Genomic and single-cell landscape reveals novel drivers and therapeutic vulnerabilities of transformed cutaneous T-cell lymphoma. Cancer Discovery. PMID 35247891 DOI: 10.1158/2159-8290.CD-21-1207  0.484
2022 Kornepati AVR, Boyd JT, Murray CE, Saifetyarova J, de la Peña Avalos B, Rogers CM, Bai H, Padron AS, Liao Y, Ontiveros C, Svatek RS, Hromas R, Li R, Hu Y, Conejo-Garcia JR, et al. Tumor-intrinsic PD-L1 promotes DNA repair in distinct cancers and suppresses PARP inhibitor-induced synthetic lethality. Cancer Research. PMID 35247877 DOI: 10.1158/0008-5472.CAN-21-2076  0.374
2022 Peres LC, Colin-Leitzinger C, Sinha S, Marks JR, Conejo-Garcia JR, Alberg AJ, Bandera EV, Berchuck A, Bondy ML, Christensen BC, Cote ML, Doherty JA, Moorman PG, Peters ES, Moran Segura C, et al. Racial differences in the tumor immune landscape and survival of women with high-grade serous ovarian carcinoma. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 35244678 DOI: 10.1158/1055-9965.EPI-21-1334  0.4
2022 Yu X, Cen L, Chen YA, Markowitz J, Shaw TI, Tsai KY, Conejo-Garcia JR, Wang X. Tumor expression quantitative trait methylation screening reveals distinct CpG panels for deconvolving cancer immune signatures. Cancer Research. PMID 35176128 DOI: 10.1158/0008-5472.CAN-21-3113  0.426
2022 Chaurio RA, Anadon CM, Lee Costich T, Payne KK, Biswas S, Harro CM, Moran C, Ortiz AC, Cortina C, Rigolizzo KE, Sprenger KB, Mine JA, Innamarato P, Mandal G, Powers JJ, ... ... Conejo-Garcia JR, et al. TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures. Immunity. 55: 115-128.e9. PMID 35021053 DOI: 10.1016/j.immuni.2021.12.007  0.533
2022 Gardner A, de Mingo Pulido Á, Hänggi K, Bazargan S, Onimus A, Kasprzak A, Conejo-Garcia JR, Rejniak KA, Ruffell B. TIM-3 blockade enhances IL-12-dependent antitumor immunity by promoting CD8 T cell and XCR1 dendritic cell spatial co-localization. Journal For Immunotherapy of Cancer. 10. PMID 34987021 DOI: 10.1136/jitc-2021-003571  0.492
2021 Mandal G, Biswas S, Anadon CM, Yu X, Gatenbee CD, Prabhakaran S, Payne KK, Chaurio RA, Martin A, Innamarato P, Moran C, Powers JJ, Harro CM, Mine JA, Sprenger KB, ... ... Conejo-Garcia JR, et al. IgA-dominated humoral immune responses govern patients' outcome in endometrial cancer. Cancer Research. PMID 34949671 DOI: 10.1158/0008-5472.CAN-21-2376  0.527
2021 Engelhard V, Conejo-Garcia JR, Ahmed R, Nelson BH, Willard-Gallo K, Bruno TC, Fridman WH. B cells and cancer. Cancer Cell. PMID 34597591 DOI: 10.1016/j.ccell.2021.09.007  0.511
2021 Koşaloğlu-Yalçın Z, Blazeska N, Carter H, Nielsen M, Cohen E, Kufe D, Conejo-Garcia J, Robbins P, Schoenberger SP, Peters B, Sette A. The Cancer Epitope Database and Analysis Resource: A Blueprint for the Establishment of a New Bioinformatics Resource for Use by the Cancer Immunology Community. Frontiers in Immunology. 12: 735609. PMID 34504503 DOI: 10.3389/fimmu.2021.735609  0.308
2021 Creelan BC, Wang C, Teer JK, Toloza EM, Yao J, Kim S, Landin AM, Mullinax JE, Saller JJ, Saltos AN, Noyes DR, Montoya LB, Curry W, Pilon-Thomas SA, Chiappori AA, ... ... Conejo-Garcia JR, et al. Tumor-infiltrating lymphocyte treatment for anti-PD-1-resistant metastatic lung cancer: a phase 1 trial. Nature Medicine. PMID 34385708 DOI: 10.1038/s41591-021-01462-y  0.433
2021 Li R, Berglund A, Zemp L, Dhillon J, Putney R, Kim Y, Jain RK, Grass GD, Conejo-Garcia J, Mulé JJ. The 12-CK Score: Global Measurement of Tertiary Lymphoid Structures. Frontiers in Immunology. 12: 694079. PMID 34267760 DOI: 10.3389/fimmu.2021.694079  0.469
2021 Li R, Zhang J, Gilbert SM, Conejo-Garcia J, Mulé JJ. Using oncolytic viruses to ignite the tumour immune microenvironment in bladder cancer. Nature Reviews. Urology. PMID 34183833 DOI: 10.1038/s41585-021-00483-z  0.339
2021 Reyes RM, Deng Y, Zhang D, Ji N, Mukherjee N, Wheeler K, Gupta HB, Padron AS, Kancharla A, Zhang C, Garcia M, Kornepati AVR, Boyman O, Conejo-Garcia JR, Svatek RS, et al. CD122-directed interleukin-2 treatment mechanisms in bladder cancer differ from αPD-L1 and include tissue-selective γδ T cell activation. Journal For Immunotherapy of Cancer. 9. PMID 33849925 DOI: 10.1136/jitc-2020-002051  0.354
2021 Wilson CM, Fridley BL, Conejo-Garcia JR, Wang X, Yu X. Wide and deep learning for automatic cell type identification. Computational and Structural Biotechnology Journal. 19: 1052-1062. PMID 33613870 DOI: 10.1016/j.csbj.2021.01.027  0.311
2021 Biswas S, Mandal G, Payne KK, Anadon CM, Gatenbee CD, Chaurio RA, Costich TL, Moran C, Harro CM, Rigolizzo KE, Mine JA, Trillo-Tinoco J, Sasamoto N, Terry KL, Marchion D, ... ... Conejo-Garcia JR, et al. IgA transcytosis and antigen recognition govern ovarian cancer immunity. Nature. PMID 33536615 DOI: 10.1038/s41586-020-03144-0  0.432
2021 Jain MD, Zhao H, Wang X, Atkins R, Menges M, Reid K, Spitler K, Faramand R, Bachmeier CA, Dean EA, Cao B, Chavez JC, Shah BD, Lazaryan A, Nishihori T, ... ... Conejo-Garcia J, et al. Tumor interferon signaling and suppressive myeloid cells associate with CAR T cell failure in large B cell lymphoma. Blood. PMID 33512407 DOI: 10.1182/blood.2020007445  0.502
2021 Jia Y, Kodumudi KN, Ramamoorthi G, Basu A, Snyder C, Wiener D, Pilon-Thomas S, Zhang H, Greene MI, Mo Q, Tong Z, Chen YZ, Costa RLB, Han H, Lee C, ... ... Conejo-Garcia JR, et al. Th1 cytokine interferon gamma improves response in HER2 breast cancer by modulating the ubiquitin proteasomal pathway. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33412308 DOI: 10.1016/j.ymthe.2020.12.037  0.368
2020 Chaudhary R, Slebos RJC, Song F, McCleary-Sharpe KP, Masannat J, Tan AC, Wang X, Amaladas N, Wu W, Hall GE, Conejo-Garcia JR, Hernanez-Prera JC, Chung CH. Effects of checkpoint kinase 1 inhibition by prexasertib on the tumor immune microenvironment of head and neck squamous cell carcinoma. Molecular Carcinogenesis. PMID 33378592 DOI: 10.1002/mc.23275  0.438
2020 Harro CM, Perez-Sanz J, Costich TL, Payne KK, Anadon Galindo CM, Chaurio RA, Biswas S, Mandal G, Rigolizzo KE, Sprenger KB, Mine JA, Showe L, Yu X, Liu K, Rodriguez PC, ... ... Conejo-Garcia JR, et al. Methyltransferase inhibitors restore SATB1 protective activity against cutaneous T cell lymphoma in mice. The Journal of Clinical Investigation. PMID 33270606 DOI: 10.1172/JCI135711  0.371
2020 Conejo-Garcia JR, Biswas S, Chaurio R. Humoral immune responses: Unsung heroes of the war on cancer. Seminars in Immunology. 101419. PMID 33183950 DOI: 10.1016/j.smim.2020.101419  0.52
2020 Drerup JM, Deng Y, Pandeswara SL, Padrón ÁS, Reyes RM, Zhang X, Mendez J, Liu A, Clark CA, Chen W, Conejo-Garcia JR, Hurez V, Gupta H, Curiel TJ. CD122-selective IL-2 complexes reduce immunosuppression, promote Treg fragility, and sensitize tumor response to PD-L1 blockade. Cancer Research. PMID 32948605 DOI: 10.1158/0008-5472.Can-20-0002  0.42
2020 Payne KK, Mine JA, Biswas S, Chaurio RA, Perales-Puchalt A, Anadon CM, Costich TL, Harro CM, Walrath J, Ming Q, Tcyganov E, Buras AL, Rigolizzo KE, Mandal G, Lajoie J, ... ... Conejo-Garcia JR, et al. BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells. Science (New York, N.Y.). 369: 942-949. PMID 32820120 DOI: 10.1126/Science.Aay2767  0.798
2020 Hamaidi I, Zhang L, Kim N, Wang MH, Iclozan C, Fang B, Liu M, Koomen JM, Berglund AE, Yoder SJ, Yao J, Engelman RW, Creelan BC, Conejo-Garcia JR, Antonia SJ, et al. Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells. Cell Metabolism. PMID 32768387 DOI: 10.1016/J.Cmet.2020.07.008  0.548
2020 Wang X, Yu X, Krauthammer M, Hugo W, Duan C, Kanetsky PA, Teer JK, Thompson ZJ, Kalos D, Smalley KSM, Tsai KY, Sondak VK, Chen YA, Conejo-Garcia JR. The association of MUC16 mutation with tumor mutation burden and its prognostic implications in cutaneous melanoma. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 32611582 DOI: 10.1158/1055-9965.Epi-20-0307  0.314
2020 Annapragada A, Sikora A, Bollard C, Conejo-Garcia J, Cruz CR, Demehri S, Demetriou M, Demirdjian L, Fong L, Horowitz M, Hutson A, Kadash-Edmondson K, Kufe D, Lipkin S, Liu S, et al. Cancer Moonshot Immuno-Oncology Translational Network (IOTN): accelerating the clinical translation of basic discoveries for improving immunotherapy and immunoprevention of cancer. Journal For Immunotherapy of Cancer. 8. PMID 32554617 DOI: 10.1136/Jitc-2020-000796  0.303
2020 Schipper J, Westerhuis JJ, Beddows I, Madaj Z, Monsma D, Hostetter G, Kiupel M, Conejo-Garcia JR, Sempere LF. Loss of microRNA-21 leads to profound stromal remodeling and short survival in K-Ras-driven mouse models of pancreatic cancer. International Journal of Cancer. PMID 32388866 DOI: 10.1002/Ijc.33041  0.302
2020 Mohamed E, Sierra RA, Trillo-Tinoco J, Cao Y, Innamarato P, Payne KK, de Mingo Pulido A, Mandula J, Zhang S, Thevenot P, Biswas S, Abdalla SK, Costich TL, Hänggi K, Anadon CM, ... ... Conejo-Garcia JR, et al. The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling. Immunity. 52: 668-682.e7. PMID 32294407 DOI: 10.1016/J.Immuni.2020.03.004  0.794
2020 Conejo-Garcia JR, Rodriguez PC. c-Maf: A bad influence in the education of macrophages. The Journal of Clinical Investigation. PMID 32175921 DOI: 10.1172/Jci135444  0.559
2020 Creelan B, Wang C, Teer J, Toloza E, Mullinax J, Yao J, Koomen J, Kim S, Chiappori A, Saller J, Montoya L, Landin AM, Tanvetyanon T, Fang B, Thompson Z, ... ... Conejo-Garcia J, et al. Abstract CT056: Durable complete responses to adoptive cell transfer using tumor infiltrating lymphocytes (TIL) in non-small cell lung cancer (NSCLC): A phase I trial Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-Ct056  0.439
2020 Schipper J, Jackson B, Beddows I, Kenyon E, Powell K, Robertson N, Hostetter G, Kiupel M, Moore A, Conejo-Garcia J, sempere L. Abstract 5719: Tumor-suppressive stromal activity of pro-fibrogenic microRNA-21 in initiation and progression of K-Ras-driven mouse models of pancreatic cancer Tumor Biology. DOI: 10.1158/1538-7445.Am2020-5719  0.427
2019 de la Iglesia JV, Slebos RJ, Martin-Gomez L, Wang X, Teer JK, Tan AC, Gerke TA, Aden-Buie G, Van Veen T, Masannat J, Chaudhary R, Song F, Fournier M, Siegel EM, Schabath MB, ... ... Conejo-Garcia JR, et al. Effects of tobacco smoking on the tumor immune microenvironment in head and neck squamous cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31848186 DOI: 10.1158/1078-0432.Ccr-19-1769  0.384
2019 Biswas S, Mandal G, Roy Chowdhury S, Purohit S, Payne KK, Anadon C, Gupta A, Swanson P, Yu X, Conejo-Garcia JR, Bhattacharyya A. Exosomes Produced by Mesenchymal Stem Cells Drive Differentiation of Myeloid Cells into Immunosuppressive M2-Polarized Macrophages in Breast Cancer. Journal of Immunology (Baltimore, Md. : 1950). PMID 31704881 DOI: 10.4049/Jimmunol.1900692  0.55
2019 Cao Y, Trillo-Tinoco J, Sierra RA, Anadon C, Dai W, Mohamed E, Cen L, Costich TL, Magliocco A, Marchion D, Klar R, Michel S, Jaschinski F, Reich RR, Mehrotra S, ... ... Conejo-Garcia JR, et al. Publisher Correction: ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nature Communications. 10: 3680. PMID 31417079 DOI: 10.1038/S41467-019-11563-5  0.721
2019 Trillo-Tinoco J, Sierra RA, Mohamed E, Cao Y, de Mingo-Pulido Á, Gilvary DL, Anadon CM, Costich TL, Wei S, Flores ER, Ruffell B, Conejo-Garcia JR, Rodriguez PC. AMPK alpha-1 intrinsically regulates the function and differentiation of tumor myeloid-derived suppressor cells. Cancer Research. PMID 31409640 DOI: 10.1158/0008-5472.Can-19-0880  0.592
2019 Conejo-Garcia JR. Breaking barriers for T cells by targeting the EPHA2/TGF-β/COX-2 axis in pancreatic cancer. The Journal of Clinical Investigation. 130. PMID 31355777 DOI: 10.1172/Jci130316  0.601
2019 Yu X, Chen YA, Conejo-Garcia JR, Chung CH, Wang X. Estimation of immune cell content in tumor using single-cell RNA-seq reference data. Bmc Cancer. 19: 715. PMID 31324168 DOI: 10.1186/S12885-019-5927-3  0.499
2019 Saglam O, Zhou J, Wang X, Conejo-Garcia JR. PD-L1 Expression Correlates With Young Age and CD8+ TIL Density in Poorly Differentiated Cervical Squamous Cell Carcinoma. International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. PMID 31274701 DOI: 10.1097/Pgp.0000000000000623  0.395
2019 Dangaj D, Bruand M, Grimm AJ, Ronet C, Barras D, Duttagupta PA, Lanitis E, Duraiswamy J, Tanyi JL, Benencia F, Conejo-Garcia J, Ramay HR, Montone KT, Powell DJ, Gimotty PA, et al. Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors. Cancer Cell. 35: 885-900.e10. PMID 31185212 DOI: 10.1016/J.Ccell.2019.05.004  0.628
2019 Cao Y, Trillo-Tinoco J, Sierra RA, Anadon C, Dai W, Mohamed E, Cen L, Costich TL, Magliocco A, Marchion D, Klar R, Michel S, Jaschinski F, Reich RR, Mehrotra S, ... ... Conejo-Garcia JR, et al. ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nature Communications. 10: 1280. PMID 30894532 DOI: 10.1038/S41467-019-09263-1  0.783
2019 Guo X, Liu Y, Kim JL, Kim EY, Kim EQ, Jansen A, Li K, Chan M, Keenan BT, Conejo-Garcia J, Lim DC. Effect of cyclical intermittent hypoxia on Ad5CMVCre induced solitary lung cancer progression and spontaneous metastases in the KrasG12D+; p53fl/fl; myristolated p110fl/fl ROSA-gfp mouse. Plos One. 14: e0212930. PMID 30811514 DOI: 10.1371/Journal.Pone.0212930  0.318
2019 Perales-Puchalt A, Svoronos N, Villarreal DO, Zankharia U, Reuschel E, Wojtak K, Payne KK, Duperret EK, Muthumani K, Conejo-Garcia JR, Weiner DB. IL-33 delays metastatic peritoneal cancer progression inducing an allergic microenvironment. Oncoimmunology. 8: e1515058. PMID 30546956 DOI: 10.1080/2162402X.2018.1515058  0.517
2019 Schipper J, Beddows I, Kiupel M, Conejo-Garcia J, Sempere L. Abstract A48: Genetic ablation of microRNA-21 profoundly remodels stroma and shortens survival of K-Ras-driven pancreatic cancer mouse models Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A48  0.436
2018 Betts BC, Locke FL, Sagatys EM, Pidala J, Walton K, Menges M, Reff J, Saha A, Djeu JY, Kiluk JV, Lee MC, Kim J, Kang CW, Tang CA, Frieling J, ... ... Conejo-Garcia JR, et al. Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity. Frontiers in Immunology. 9: 2887. PMID 30574153 DOI: 10.3389/Fimmu.2018.02887  0.518
2018 Song M, Sandoval TA, Chae CS, Chopra S, Tan C, Rutkowski MR, Raundhal M, Chaurio RA, Payne KK, Konrad C, Bettigole SE, Shin HR, Crowley MJP, Cerliani JP, Kossenkov AV, ... ... Conejo-Garcia JR, et al. IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity. Nature. PMID 30305738 DOI: 10.1038/S41586-018-0597-X  0.749
2018 Saglam O, Conejo-Garcia J. PD-1/PD-L1 immune checkpoint inhibitors in advanced cervical cancer. Integrative Cancer Science and Therapeutics. 5. PMID 29955379 DOI: 10.15761/Icst.1000272  0.376
2018 Kugel CH, Douglass SM, Webster MR, Kaur A, Liu Q, Yin X, Weiss SA, Darvishian F, Al-Rohil RN, Ndoye A, Behera R, Alicea GM, Ecker BL, Fane M, Allegrezza MJ, ... ... Conejo-Garcia JR, et al. Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29898988 DOI: 10.1158/1078-0432.Ccr-18-1116  0.364
2018 Fukumoto T, Park PH, Wu S, Fatkhutdinov N, Karakashev S, Nacarelli T, Kossenkov AV, Speicher DW, Jean S, Zhang L, Wang TL, Shih IM, Conejo-Garcia JR, Bitler BG, Zhang R. Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer. Cell Reports. 22: 3393-3400. PMID 29590609 DOI: 10.1016/J.Celrep.2018.03.019  0.373
2018 Karakashev S, Zhu H, Wu S, Yokoyama Y, Bitler BG, Park PH, Lee JH, Kossenkov AV, Gaonkar KS, Yan H, Drapkin R, Conejo-Garcia JR, Speicher DW, Ordog T, Zhang R. CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity. Nature Communications. 9: 631. PMID 29434212 DOI: 10.1038/S41467-018-03031-3  0.509
2018 Svoronos N, Perales-Puchalt A, Conejo-Garcia JR. Abstract SY01-02: Blockade of estrogen signaling boosts antitumor immunity by dwindling cancer-promoting myelopoiesis Immunology. DOI: 10.1158/1538-7445.Am2018-Sy01-02  0.429
2018 Williams AD, Campbell JS, Aicher LD, Payne KK, Conejo-Garcia JR, Pierce RH, Tchou J. Abstract 3145: Characterization of novel immune checkpoint receptors within the breast cancer tumor microenvironment Cancer Research. 78: 3145-3145. DOI: 10.1158/1538-7445.Am2018-3145  0.528
2017 Williams AD, Payne KK, Posey AD, Hill C, Conejo-Garcia J, June CH, Tchou J. Immunotherapy for Breast Cancer: Current and Future Strategies. Current Surgery Reports. 5. PMID 29657904 DOI: 10.1007/S40137-017-0194-1  0.419
2017 Tchou J, Zhao Y, Levine BL, Zhang PJ, Davis MM, Melenhorst JJ, Kulikovskaya I, Brennan AL, Liu X, Lacey SF, Posey A, Williams AD, So A, Conejo-Garcia JR, Plesa G, et al. Safety and efficacy of intratumoral injections of chimeric antigen receptor (CAR) T cells in metastatic breast cancer. Cancer Immunology Research. PMID 29109077 DOI: 10.1158/2326-6066.Cir-17-0189  0.569
2017 Bitler BG, Wu S, Park PH, Hai Y, Aird KM, Wang Y, Zhai Y, Kossenkov AV, Vara-Ailor A, Rauscher Iii FJ, Zou W, Speicher DW, Huntsman DG, Conejo-Garcia JR, Cho KR, et al. ARID1A-mutated ovarian cancers depend on HDAC6 activity. Nature Cell Biology. PMID 28737768 DOI: 10.1038/Ncb3582  0.309
2017 Allegrezza MJ, Conejo-Garcia JR. Targeted Therapy and Immunosuppression in the Tumor Microenvironment. Trends in Cancer. 3: 19-27. PMID 28718424 DOI: 10.1016/J.Trecan.2016.11.009  0.507
2017 Stephen TL, Payne KK, Chaurio RA, Allegrezza MJ, Zhu H, Perez-Sanz J, Perales-Puchalt A, Nguyen JM, Vara-Ailor AE, Eruslanov EB, Borowsky ME, Zhang R, Laufer TM, Conejo-Garcia JR. SATB1 Expression Governs Epigenetic Repression of PD-1 in Tumor-Reactive T Cells. Immunity. 46: 51-64. PMID 28099864 DOI: 10.1016/J.Immuni.2016.12.015  0.548
2017 Zhu H, Bengsch F, Svoronos N, Rutkowski MR, Bitler BG, Allegrezza MJ, Yokoyama Y, Bradner JE, Conejo-Garcia JR, Zhang R. Abstract AP31: TARGETING PD–L1/PD1 PATHWAY THROUGH BET PROTEIN INHIBITION IN EPITHELIAL OVARIAN CANCER Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Ovcasymp16-Ap31  0.392
2017 Stadanlick J, Rao A, Annunziata M, Moon E, O'brien S, Bhojnagarwala P, Feldman M, Hancock W, Conejo-Garcia J, Singhal S, Albelda S, Eruslanov E. Abstract 3707: Tumor-associated neutrophils with antigen-presenting features in early-stage human lung cancer Immunology. 77: 3707-3707. DOI: 10.1158/1538-7445.Am2017-3707  0.435
2017 Williams AD, Payne KK, So A, Conejo-Garcia J, Tchou JC. Characterization of Novel Immune Checkpoint Receptors within the Breast Cancer Tumor Microenvironment Journal of the American College of Surgeons. 225: S21. DOI: 10.1016/J.Jamcollsurg.2017.07.024  0.492
2016 Gupta HB, Clark CA, Yuan B, Sareddy G, Pandeswara S, Padron AS, Hurez V, Conejo-Garcia J, Vadlamudi R, Li R, Curiel TJ. Tumor cell-intrinsic PD-L1 promotes tumor-initiating cell generation and functions in melanoma and ovarian cancer. Signal Transduction and Targeted Therapy. 1. PMID 28798885 DOI: 10.1038/Sigtrans.2016.30  0.484
2016 Yokoyama Y, Zhu H, Lee JH, Kossenkov AV, Wu SY, Wickramasinghe JM, Yin X, Palozola KC, Gardini A, Showe LC, Zaret KS, Liu Q, Speicher D, Conejo-Garcia JR, Bradner JE, et al. BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer. Cancer Research. 76: 6320-6330. PMID 27803105 DOI: 10.1158/0008-5472.Can-16-0854  0.462
2016 Allegrezza MJ, Rutkowski MR, Stephen TL, Svoronos N, Perales-Puchalt A, Nguyen JM, Payne KK, Singhal S, Eruslanov EB, Tchou J, Conejo-Garcia JR. Trametinib Drives T-cell-Dependent Control of KRAS-Mutated Tumors by Inhibiting Pathological Myelopoiesis. Cancer Research. 76: 6253-6265. PMID 27803104 DOI: 10.1158/0008-5472.Can-16-1308  0.635
2016 Sheen MR, Marotti JD, Allegrezza MJ, Rutkowski M, Conejo-Garcia JR, Fiering S. Constitutively activated PI3K accelerates tumor initiation and modifies histopathology of breast cancer. Oncogenesis. 5: e267. PMID 27797363 DOI: 10.1038/oncsis.2016.65  0.354
2016 Svoronos N, Perales-Puchalt A, Allegrezza MJ, Rutkowski MR, Payne KK, Tesone AJ, Nguyen JM, Curiel TJ, Cadungog MG, Singhal S, Eruslanov EB, Zhang P, Tchou J, Zhang R, Conejo-Garcia JR. Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Supressor Cells. Cancer Discovery. PMID 27694385 DOI: 10.1158/2159-8290.Cd-16-0502  0.569
2016 Clark CA, Gupta H, Sareddy GR, Pandeswara S, Lao S, Yuan B, Drerup JM, Padron A, Conejo-Garcia JR, Murthy K, Liu Y, Turk MJ, Thedieck K, Hurez V, Li R, et al. Tumor-intrinsic PD-L1 signals regulate cell growth, pathogenesis and autophagy in ovarian cancer and melanoma. Cancer Research. PMID 27671674 DOI: 10.1158/0008-5472.Can-16-0258  0.388
2016 Goldman AR, Bitler BG, Schug Z, Conejo-Garcia JR, Zhang R, Speicher DW. The Primary Effect on the Proteome of ARID1A-Mutated Ovarian Clear Cell Carcinoma is Downregulation of the Mevalonate Pathway at the Post-Transcriptional Level. Molecular & Cellular Proteomics : McP. PMID 27654507 DOI: 10.1074/Mcp.M116.062539  0.361
2016 Zhu H, Bengsch F, Svoronos N, Rutkowski MR, Bitler BG, Allegrezza MJ, Yokoyama Y, Kossenkov AV, Bradner JE, Conejo-Garcia JR, Zhang R. BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression. Cell Reports. 16: 2829-2837. PMID 27626654 DOI: 10.1016/J.Celrep.2016.08.032  0.488
2016 Perales-Puchalt A, Svoronos N, Rutkowski MR, Allegrezza MJ, Tesone AJ, Payne KK, Wickramasinghe J, Nguyen JM, O'Brien SW, Gumireddy K, Huang Q, Cadungog M, Connolly DC, Tchou J, Curiel TJ, ... Conejo-Garcia JR, et al. FOLLICLE-STIMULATING HORMONE RECEPTOR IS EXPRESSED BY MOST OVARIAN CANCER SUBTYPES AND IS A SAFE AND EFFECTIVE IMMUNOTHERAPEUTIC TARGET. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27435394 DOI: 10.1158/1078-0432.Ccr-16-0492  0.42
2016 Singhal S, Bhojnagarwala PS, O'Brien S, Moon EK, Garfall AL, Rao AS, Quatromoni JG, Stephen TL, Litzky L, Deshpande C, Feldman MD, Hancock WW, Conejo-Garcia JR, Albelda SM, Eruslanov EB. Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer. Cancer Cell. PMID 27374224 DOI: 10.1016/J.Ccell.2016.06.001  0.608
2016 Mari ER, Rasouli J, Ciric B, Moore JN, Conejo-Garcia JR, Rajasagi N, Zhang GX, Rabinovich GA, Rostami A. Galectin-1 is essential for the induction of MOG35-55 -based intravenous tolerance in experimental autoimmune encephalomyelitis. European Journal of Immunology. PMID 27151444 DOI: 10.1002/Eji.201546212  0.386
2016 Conejo-Garcia JR, Rutkowski MR, Cubillos-Ruiz JR. State-of-the-art of regulatory dendritic cells in cancer. Pharmacology & Therapeutics. PMID 27118338 DOI: 10.1016/J.Pharmthera.2016.04.003  0.77
2016 Rabinovich GA, Conejo-García JR. Shaping the immune landscape in cancer by galectin-driven regulatory pathways. Journal of Molecular Biology. PMID 27038510 DOI: 10.1016/J.Jmb.2016.03.021  0.553
2016 Allegrezza MJ, Rutkowski MR, Stephen TL, Svoronos N, Tesone AJ, Perales-Puchalt A, Nguyen JM, Sarmin F, Sheen MR, Jeng EK, Tchou J, Wong HC, Fiering SN, Conejo-Garcia JR. IL-15 AGONISTS OVERCOME THE IMMUNOSUPPRESSIVE EFFECTS OF MEK INHIBITORS. Cancer Research. PMID 26980764 DOI: 10.1158/0008-5472.Can-15-2808  0.496
2016 Tesone AJ, Rutkowski MR, Brencicova E, Svoronos N, Perales-Puchalt A, Stephen TL, Allegrezza MJ, Payne KK, Nguyen JM, Wickramasinghe J, Tchou J, Borowsky ME, Rabinovich GA, Kossenkov AV, Conejo-Garcia JR. Satb1 Overexpression Drives Tumor-Promoting Activities in Cancer-Associated Dendritic Cells. Cell Reports. PMID 26876172 DOI: 10.1016/J.Celrep.2016.01.056  0.524
2016 Rutkowski MR, Conejo-Garcia JR. Abstract IA32: Commensal microorganisms and polymorphic mucosal surfaces determine the evolution of distal metastatic tumors Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-Ia32  0.583
2016 Eruslanov E, Bhojnagarwala P, Quatromoni J, O'Brien S, Moon E, Stephen T, Rao A, Garfall A, Hancock W, Conejo-Garcia J, Deshpande C, Feldman M, Singhal S, Albelda S. Abstract A02: The origin and role of APC-like hybrid tumor-associated neutrophils in early-stage human lung cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-A02  0.629
2015 Sheen MR, Warner SL, Fields JL, Conejo-Garcia JR, Fiering S. Myristoylated p110α Causes Embryonic Death Due to Developmental and Vascular Defects. Open Life Sciences. 10: 461-478. PMID 27482546 DOI: 10.1515/Biol-2015-0048  0.314
2015 Conejo-Garcia JR, Rutkowski MR. Small but Mighty: Selected Commensal Bacterial Species Determine the Effectiveness of Anti-cancer Immunotherapies. Immunity. 43: 1037-9. PMID 26682980 DOI: 10.1016/J.Immuni.2015.11.014  0.327
2015 Wang Z, Deng Z, Dahmane N, Tsai K, Wang P, Williams DR, Kossenkov AV, Showe LC, Zhang R, Huang Q, Conejo-Garcia JR, Lieberman PM. Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes. Proceedings of the National Academy of Sciences of the United States of America. 112: E6293-E6300. PMID 26578789 DOI: 10.1073/Pnas.1505962112  0.439
2015 Rutkowski MR, Conejo-Garcia JR. TLR5 signaling, commensal microbiota and systemic tumor promoting inflammation: the three parcae of malignant progression. Oncoimmunology. 4: e1021542. PMID 26405577 DOI: 10.1080/2162402X.2015.1021542  0.5
2015 Rutkowski MR, Svoronos N, Perales-Puchalt A, Conejo-Garcia JR. The Tumor Macroenvironment: Cancer-Promoting Networks Beyond Tumor Beds. Advances in Cancer Research. 128: 235-62. PMID 26216635 DOI: 10.1016/Bs.Acr.2015.04.011  0.535
2015 Cubillos-Ruiz JR, Silberman PC, Rutkowski MR, Chopra S, Perales-Puchalt A, Song M, Zhang S, Bettigole SE, Gupta D, Holcomb K, Ellenson LH, Caputo T, Lee AH, Conejo-Garcia JR, Glimcher LH. ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis. Cell. 161: 1527-38. PMID 26073941 DOI: 10.1016/J.Cell.2015.05.025  0.799
2015 Rutkowski MR, Conejo-Garcia JR. Size does not matter: commensal microorganisms forge tumor-promoting inflammation and anti-tumor immunity. Oncoscience. 2: 239-46. PMID 25897427  0.446
2015 Villarreal DO, Svoronos N, Wise MC, Shedlock DJ, Morrow MP, Conejo-Garcia JR, Weiner DB. Molecular adjuvant IL-33 enhances the potency of a DNA vaccine in a lethal challenge model. Vaccine. PMID 25887087 DOI: 10.1016/J.Vaccine.2015.03.086  0.454
2015 Bitler BG, Aird KM, Garipov A, Li H, Amatangelo M, Kossenkov AV, Schultz DC, Liu Q, Shih IeM, Conejo-Garcia JR, Speicher DW, Zhang R. Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers. Nature Medicine. 21: 231-8. PMID 25686104 DOI: 10.1038/Nm.3799  0.354
2015 Rutkowski MR, Stephen TL, Svoronos N, Allegrezza MJ, Tesone AJ, Perales-Puchalt A, Brencicova E, Escovar-Fadul X, Nguyen JM, Cadungog MG, Zhang R, Salatino M, Tchou J, Rabinovich GA, Conejo-Garcia JR. Microbially driven TLR5-dependent signaling governs distal malignant progression through tumor-promoting inflammation. Cancer Cell. 27: 27-40. PMID 25533336 DOI: 10.1016/J.Ccell.2014.11.009  0.519
2015 Rutkowski MR, Conejo-Garcia JR. Size does not matter: Commensal microorganisms forge tumorpromoting inflammation and anti-tumor immunity Oncoscience. 2: 239-246. DOI: 10.18632/oncoscience.145  0.422
2015 Eruslanov E, Bhojnagarwala P, Quatromoni J, Stephen T, Ranganathan A, Deshpande C, Akimova T, Vachani A, Litzky L, Hancock W, Conejo-Garcia J, Feldman M, Singhal S, Albelda S. Abstract A66: Tumor-associated neutrophils in early stage human lung cancer are not immunosuppressive, but exhibit an inflammatory phenotype and provide accessory signals for T cell activation Cancer Immunology Research. 3. DOI: 10.1158/2326-6074.Tumimm14-A66  0.627
2014 Eruslanov EB, Bhojnagarwala PS, Quatromoni JG, Stephen TL, Ranganathan A, Deshpande C, Akimova T, Vachani A, Litzky L, Hancock WW, Conejo-Garcia JR, Feldman M, Albelda SM, Singhal S. Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer. The Journal of Clinical Investigation. 124: 5466-80. PMID 25384214 DOI: 10.1172/Jci77053  0.568
2014 Stephen TL, Rutkowski MR, Allegrezza MJ, Perales-Puchalt A, Tesone AJ, Svoronos N, Nguyen JM, Sarmin F, Borowsky ME, Tchou J, Conejo-Garcia JR. Transforming growth factor β-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression. Immunity. 41: 427-39. PMID 25238097 DOI: 10.1016/J.Immuni.2014.08.012  0.545
2014 Li YR, Xian RR, Ziober A, Conejo-Garcia J, Perales-Puchalt A, June CH, Zhang PJ, Tchou J. Mesothelin expression is associated with poor outcomes in breast cancer. Breast Cancer Research and Treatment. 147: 675-84. PMID 25193277 DOI: 10.1007/S10549-014-3077-5  0.385
2014 Tchou J, Conejo-Garcia J. Fibroblast activation protein, a potential diagnostic and therapeutic target for cancer-reply. Human Pathology. 45: 1553-4. PMID 24792620 DOI: 10.1016/J.Humpath.2013.11.022  0.339
2014 Rutkowski MR, Allegrezza MJ, Svoronos N, Tesone AJ, Stephen TL, Perales-Puchalt A, Nguyen J, Zhang PJ, Fiering SN, Tchou J, Conejo-Garcia JR. Initiation of metastatic breast carcinoma by targeting of the ductal epithelium with adenovirus-cre: a novel transgenic mouse model of breast cancer. Journal of Visualized Experiments : Jove. PMID 24748051 DOI: 10.3791/51171  0.508
2014 Toraya-Brown S, Sheen MR, Zhang P, Chen L, Baird JR, Demidenko E, Turk MJ, Hoopes PJ, Conejo-Garcia JR, Fiering S. Local hyperthermia treatment of tumors induces CD8(+) T cell-mediated resistance against distal and secondary tumors. Nanomedicine : Nanotechnology, Biology, and Medicine. 10: 1273-85. PMID 24566274 DOI: 10.1016/J.Nano.2014.01.011  0.565
2013 Cubillos-Ruiz JR, Rutkowski MR, Tchou J, Conejo-Garcia JR. Reprogramming immune responses via microRNA modulation. Microrna Diagnostics and Therapeutics. 1. PMID 25285232 DOI: 10.2478/Micrnat-2013-0001  0.659
2013 Tesone AJ, Svoronos N, Allegrezza MJ, Conejo-Garcia JR. Pathological mobilization and activities of dendritic cells in tumor-bearing hosts: challenges and opportunities for immunotherapy of cancer. Frontiers in Immunology. 4: 435. PMID 24339824 DOI: 10.3389/Fimmu.2013.00435  0.62
2013 Tchou J, Zhang PJ, Bi Y, Satija C, Marjumdar R, Stephen TL, Lo A, Chen H, Mies C, June CH, Conejo-Garcia J, Puré E. Fibroblast activation protein expression by stromal cells and tumor-associated macrophages in human breast cancer. Human Pathology. 44: 2549-57. PMID 24074532 DOI: 10.1016/J.Humpath.2013.06.016  0.496
2013 Amatangelo MD, Garipov A, Li H, Conejo-Garcia JR, Speicher DW, Zhang R. Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition. Cell Cycle (Georgetown, Tex.). 12: 2113-9. PMID 23759589 DOI: 10.4161/Cc.25163  0.448
2013 Baird JR, Fox BA, Sanders KL, Lizotte PH, Cubillos-Ruiz JR, Scarlett UK, Rutkowski MR, Conejo-Garcia JR, Fiering S, Bzik DJ. Avirulent Toxoplasma gondii generates therapeutic antitumor immunity by reversing immunosuppression in the ovarian cancer microenvironment. Cancer Research. 73: 3842-51. PMID 23704211 DOI: 10.1158/0008-5472.Can-12-1974  0.82
2013 Tchou J, Conejo-Garcia J. Targeting the tumor stroma as a novel treatment strategy for breast cancer: shifting from the neoplastic cell-centric to a stroma-centric paradigm. Advances in Pharmacology (San Diego, Calif.). 65: 45-61. PMID 22959023 DOI: 10.1016/B978-0-12-397927-8.00003-8  0.606
2013 Toraya-Brown S, Sheen MR, Baird JR, Barry S, Demidenko E, Turk MJ, Hoopes PJ, Conejo-Garcia JR, Fiering S. Phagocytes mediate targeting of iron oxide nanoparticles to tumors for cancer therapy. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 159-71. PMID 22935885 DOI: 10.1039/C2Ib20180A  0.53
2012 Scarlett UK, Conejo-Garcia JR. Modulating the tumor immune microenvironment as an ovarian cancer treatment strategy. Expert Review of Obstetrics & Gynecology. 7: 413-419. PMID 24039628 DOI: 10.1586/Eog.12.41  0.548
2012 Cubillos-Ruiz JR, Sempere LF, Conejo-Garcia JR. Good things come in small packages: Therapeutic anti-tumor immunity induced by microRNA nanoparticles. Oncoimmunology. 1: 968-970. PMID 23162774 DOI: 10.4161/Onci.20020  0.747
2012 Rutkowski MR, Stephen TL, Conejo-Garcia JR. Anti-tumor immunity: myeloid leukocytes control the immune landscape. Cellular Immunology. 278: 21-6. PMID 23121972 DOI: 10.1016/J.Cellimm.2012.06.014  0.578
2012 Hampton TH, Ballok AE, Bomberger JM, Rutkowski MR, Barnaby R, Coutermarsh B, Conejo-Garcia JR, O'Toole GA, Stanton BA. Does the F508-CFTR mutation induce a proinflammatory response in human airway epithelial cells? American Journal of Physiology. Lung Cellular and Molecular Physiology. 303: L509-18. PMID 22821996 DOI: 10.1152/Ajplung.00226.2011  0.348
2012 Wasiuk A, Dalton DK, Schpero WL, Stan RV, Conejo-Garcia JR, Noelle RJ. Mast cells impair the development of protective anti-tumor immunity. Cancer Immunology, Immunotherapy : Cii. 61: 2273-82. PMID 22684520 DOI: 10.1007/S00262-012-1276-7  0.626
2012 Deng Z, Wang Z, Xiang C, Molczan A, Baubet V, Conejo-Garcia J, Xu X, Lieberman PM, Dahmane N. Formation of telomeric repeat-containing RNA (TERRA) foci in highly proliferating mouse cerebellar neuronal progenitors and medulloblastoma. Journal of Cell Science. 125: 4383-94. PMID 22641694 DOI: 10.1242/Jcs.108118  0.418
2012 Scarlett UK, Conejo-Garcia JR. Double agents in the war on cancer: leukocytes govern ovarian cancer progression. Oncotarget. 3: 226-7. PMID 22538964 DOI: 10.18632/Oncotarget.478  0.484
2012 Tchou J, Wang LC, Selven B, Zhang H, Conejo-Garcia J, Borghaei H, Kalos M, Vondeheide RH, Albelda SM, June CH, Zhang PJ. Mesothelin, a novel immunotherapy target for triple negative breast cancer. Breast Cancer Research and Treatment. 133: 799-804. PMID 22418702 DOI: 10.1007/S10549-012-2018-4  0.494
2012 Scarlett UK, Rutkowski MR, Rauwerdink AM, Fields J, Escovar-Fadul X, Baird J, Cubillos-Ruiz JR, Jacobs AC, Gonzalez JL, Weaver J, Fiering S, Conejo-Garcia JR. Ovarian cancer progression is controlled by phenotypic changes in dendritic cells. The Journal of Experimental Medicine. 209: 495-506. PMID 22351930 DOI: 10.1084/Jem.20111413  0.793
2012 Cubillos-Ruiz JR, Baird JR, Tesone AJ, Rutkowski MR, Scarlett UK, Camposeco-Jacobs AL, Anadon-Arnillas J, Harwood NM, Korc M, Fiering SN, Sempere LF, Conejo-Garcia JR. Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer. Cancer Research. 72: 1683-93. PMID 22307839 DOI: 10.1158/0008-5472.Can-11-3160  0.698
2011 Cubillos-Ruiz JR, Conejo-Garcia JR. It never rains but it pours: potential role of butyrophilins in inhibiting anti-tumor immune responses. Cell Cycle (Georgetown, Tex.). 10: 368-9. PMID 21270530 DOI: 10.4161/Cc.10.3.14565  0.814
2010 Cubillos-Ruiz JR, Martinez D, Scarlett UK, Rutkowski MR, Nesbeth YC, Camposeco-Jacobs AL, Conejo-Garcia JR. CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells. Oncotarget. 1: 329-38. PMID 21113407 DOI: 10.18632/Oncotarget.165  0.825
2010 Nesbeth Y, Conejo-Garcia JR. Harnessing the effect of adoptively transferred tumor-reactive T cells on endogenous (host-derived) antitumor immunity. Clinical & Developmental Immunology. 2010: 139304. PMID 21076522 DOI: 10.1155/2010/139304  0.838
2010 Sempere LF, Preis M, Yezefski T, Ouyang H, Suriawinata AA, Silahtaroglu A, Conejo-Garcia JR, Kauppinen S, Wells W, Korc M. Fluorescence-based codetection with protein markers reveals distinct cellular compartments for altered MicroRNA expression in solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 4246-55. PMID 20682703 DOI: 10.1158/1078-0432.Ccr-10-1152  0.406
2010 Nesbeth YC, Martinez DG, Toraya S, Scarlett UK, Cubillos-Ruiz JR, Rutkowski MR, Conejo-Garcia JR. CD4+ T cells elicit host immune responses to MHC class II-negative ovarian cancer through CCL5 secretion and CD40-mediated licensing of dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 5654-62. PMID 20400704 DOI: 10.4049/Jimmunol.0903247  0.841
2010 Robinson RT, Khader SA, Martino CA, Fountain JJ, Teixeira-Coelho M, Pearl JE, Smiley ST, Winslow GM, Woodland DL, Walter MJ, Conejo-Garcia JR, Gubler U, Cooper AM. Mycobacterium tuberculosis infection induces il12rb1 splicing to generate a novel IL-12Rbeta1 isoform that enhances DC migration. The Journal of Experimental Medicine. 207: 591-605. PMID 20212068 DOI: 10.1084/Jem.20091085  0.305
2010 Cubillos-Ruiz JR, Rutkowski M, Conejo-Garcia JR. Blocking ovarian cancer progression by targeting tumor microenvironmental leukocytes. Cell Cycle (Georgetown, Tex.). 9: 260-8. PMID 20023378 DOI: 10.4161/Cc.9.2.10430  0.781
2009 Cubillos-Ruiz JR, Fiering S, Conejo-Garcia JR. Nanomolecular targeting of dendritic cells for ovarian cancer therapy. Future Oncology (London, England). 5: 1189-92. PMID 19852731 DOI: 10.2217/Fon.09.101  0.737
2009 Scarlett UK, Cubillos-Ruiz JR, Nesbeth YC, Martinez DG, Engle X, Gewirtz AT, Ahonen CL, Conejo-Garcia JR. In situ stimulation of CD40 and Toll-like receptor 3 transforms ovarian cancer-infiltrating dendritic cells from immunosuppressive to immunostimulatory cells. Cancer Research. 69: 7329-37. PMID 19738057 DOI: 10.1158/0008-5472.Can-09-0835  0.843
2009 Cubillos-Ruiz JR, Engle X, Scarlett UK, Martinez D, Barber A, Elgueta R, Wang L, Nesbeth Y, Durant Y, Gewirtz AT, Sentman CL, Kedl R, Conejo-Garcia JR. Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity. The Journal of Clinical Investigation. 119: 2231-44. PMID 19620771 DOI: 10.1172/Jci37716  0.816
2009 Nesbeth Y, Scarlett U, Cubillos-Ruiz J, Martinez D, Engle X, Turk MJ, Conejo-Garcia JR. CCL5-mediated endogenous antitumor immunity elicited by adoptively transferred lymphocytes and dendritic cell depletion. Cancer Research. 69: 6331-8. PMID 19602595 DOI: 10.1158/0008-5472.Can-08-4329  0.842
2009 Pulaski HL, Spahlinger G, Silva IA, McLean K, Kueck AS, Reynolds RK, Coukos G, Conejo-Garcia JR, Buckanovich RJ. Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer. Journal of Translational Medicine. 7: 49. PMID 19545375 DOI: 10.1186/1479-5876-7-49  0.57
2009 Basu S, Eriksson M, Pioli PA, Conejo-Garcia J, Mselle TF, Yamamoto S, Wira CR, Sentman CL. Human uterine NK cells interact with uterine macrophages via NKG2D upon stimulation with PAMPs. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 61: 52-61. PMID 19086992 DOI: 10.1111/J.1600-0897.2008.00661.X  0.427
2008 Huarte E, Cubillos-Ruiz JR, Nesbeth YC, Scarlett UK, Martinez DG, Buckanovich RJ, Benencia F, Stan RV, Keler T, Sarobe P, Sentman CL, Conejo-Garcia JR. Depletion of dendritic cells delays ovarian cancer progression by boosting antitumor immunity. Cancer Research. 68: 7684-91. PMID 18768667 DOI: 10.1158/0008-5472.Can-08-1167  0.825
2008 Basu S, Pioli PA, Conejo-Garcia J, Wira CR, Sentman CL. Estradiol regulates MICA expression in human endometrial cells. Clinical Immunology (Orlando, Fla.). 129: 325-32. PMID 18728002 DOI: 10.1016/J.Clim.2008.07.005  0.375
2008 Huarte E, Cubillos-Ruiz JR, Nesbeth YC, Scarlett UK, Martinez DG, Engle XA, Rigby WF, Pioli PA, Guyre PM, Conejo-Garcia JR. PILAR is a novel modulator of human T-cell expansion. Blood. 112: 1259-68. PMID 18550855 DOI: 10.1182/Blood-2007-12-130773  0.8
2008 Balint K, Conejo-Garcia JR, Buckanovich R, Coukos G. Role of vascular leukocytes in ovarian cancer neovascularization. Advances in Experimental Medicine and Biology. 622: 273-80. PMID 18546635 DOI: 10.1007/978-0-387-68969-2_22  0.504
2007 Barber A, Zhang T, DeMars LR, Conejo-Garcia J, Roby KF, Sentman CL. Chimeric NKG2D receptor-bearing T cells as immunotherapy for ovarian cancer. Cancer Research. 67: 5003-8. PMID 17510432 DOI: 10.1158/0008-5472.Can-06-4047  0.604
2007 Bak SP, Walters JJ, Takeya M, Conejo-Garcia JR, Berwin BL. Scavenger receptor-A-targeted leukocyte depletion inhibits peritoneal ovarian tumor progression. Cancer Research. 67: 4783-9. PMID 17510407 DOI: 10.1158/0008-5472.Can-06-4410  0.59
2007 Coukos G, Conejo-Garcia JR, Buckanovich R, Benencia F. Vascular leukocytes: a population with angiogenic and immunossuppressive properties highly represented in ovarian cancer. Advances in Experimental Medicine and Biology. 590: 185-93. PMID 17191386 DOI: 10.1007/978-0-387-34814-8_13  0.326
2006 Benencia F, Courrèges MC, Conejo-García JR, Mohammed-Hadley A, Coukos G. Direct vaccination with tumor cells killed with ICP4-deficient HSVd120 elicits effective antitumor immunity. Cancer Biology & Therapy. 5: 867-74. PMID 16861891 DOI: 10.4161/Cbt.5.7.2908  0.595
2006 Buckanovich RJ, Sasaroli D, O'brien-Jenkins A, Botbyl J, Conejo-Garcia JR, Benencia F, Liotta LA, Gimotty PA, Coukos G. Use of immuno-LCM to identify the in situ expression profile of cellular constituents of the tumor microenvironment. Cancer Biology & Therapy. 5: 635-42. PMID 16627987 DOI: 10.4161/Cbt.5.6.2676  0.545
2006 Courrèges MC, Benencia F, Conejo-García JR, Zhang L, Coukos G. Preparation of apoptotic tumor cells with replication-incompetent HSV augments the efficacy of dendritic cell vaccines. Cancer Gene Therapy. 13: 182-93. PMID 16138121 DOI: 10.1038/Sj.Cgt.7700888  0.588
2005 Coukos G, Conejo-Garcia JR, Roden RB, Wu TC. Immunotherapy for gynaecological malignancies. Expert Opinion On Biological Therapy. 5: 1193-210. PMID 16120050 DOI: 10.1517/14712598.5.9.1193  0.37
2005 Benencia F, Courreges MC, Conejo-García JR, Buckanovich RJ, Zhang L, Carroll RH, Morgan MA, Coukos G. Oncolytic HSV exerts direct antiangiogenic activity in ovarian carcinoma. Human Gene Therapy. 16: 765-78. PMID 15960607 DOI: 10.1097/00002371-200411000-00029  0.456
2005 Benencia F, Courrèges MC, Conejo-García JR, Mohamed-Hadley A, Zhang L, Buckanovich RJ, Carroll R, Fraser N, Coukos G. HSV oncolytic therapy upregulates interferon-inducible chemokines and recruits immune effector cells in ovarian cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 789-802. PMID 15925544 DOI: 10.1016/J.Ymthe.2005.03.026  0.583
2005 Coukos G, Benencia F, Buckanovich RJ, Conejo-Garcia JR. The role of dendritic cell precursors in tumour vasculogenesis. British Journal of Cancer. 92: 1182-7. PMID 15785750 DOI: 10.1038/Sj.Bjc.6602476  0.41
2005 Conejo-Garcia JR, Buckanovich RJ, Benencia F, Courreges MC, Rubin SC, Carroll RG, Coukos G. Vascular leukocytes contribute to tumor vascularization. Blood. 105: 679-81. PMID 15358628 DOI: 10.1182/Blood-2004-05-1906  0.449
2004 Conejo-Garcia JR, Benencia F, Courreges MC, Kang E, Mohamed-Hadley A, Buckanovich RJ, Holtz DO, Jenkins A, Na H, Zhang L, Wagner DS, Katsaros D, Caroll R, Coukos G. Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of Vegf-A. Nature Medicine. 10: 950-8. PMID 15334073 DOI: 10.1038/Nm1097  0.451
2004 Curiel TJ, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, Evdemon-Hogan M, Conejo-Garcia JR, Zhang L, Burow M, Zhu Y, Wei S, Kryczek I, Daniel B, Gordon A, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nature Medicine. 10: 942-9. PMID 15322536 DOI: 10.1038/Nm1093  0.644
2004 Conejo-Garcia JR, Benencia F, Courreges MC, Gimotty PA, Khang E, Buckanovich RJ, Frauwirth KA, Zhang L, Katsaros D, Thompson CB, Levine B, Coukos G. Ovarian carcinoma expresses the NKG2D ligand Letal and promotes the survival and expansion of CD28- antitumor T cells. Cancer Research. 64: 2175-82. PMID 15026360 DOI: 10.1158/0008-5472.Can-03-2194  0.565
2003 Conejo-Garcia JR, Benencia F, Courreges MC, Khang E, Zhang L, Mohamed-Hadley A, Vinocur JM, Buckanovich RJ, Thompson CB, Levine B, Coukos G. Letal, A tumor-associated NKG2D immunoreceptor ligand, induces activation and expansion of effector immune cells. Cancer Biology & Therapy. 2: 446-51. PMID 14508119 DOI: 10.4161/Cbt.2.4.479  0.623
2003 Zhang L, Conejo-Garcia JR, Katsaros D, Gimotty PA, Massobrio M, Regnani G, Makrigiannakis A, Gray H, Schlienger K, Liebman MN, Rubin SC, Coukos G. Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer. The New England Journal of Medicine. 348: 203-13. PMID 12529460 DOI: 10.1056/Nejmoa020177  0.544
2001 Büchler P, Conejo-Garcia JR, Lehmann G, Müller M, Emrich T, Reber HA, Büchler MW, Friess H. Real-time quantitative PCR of telomerase mRNA is useful for the differentiation of benign and malignant pancreatic disorders. Pancreas. 22: 331-340. PMID 11345132 DOI: 10.1097/00006676-200105000-00001  0.33
2000 Goecke H, Forssmann U, Uguccioni M, Friess H, Conejo-Garcia JR, Zimmermann A, Baggiolini M, Büchler MW. Macrophages infiltrating the tissue in chronic pancreatitis express the chemokine receptor CCR5. Surgery. 128: 806-14. PMID 11056444 DOI: 10.1067/Msy.2000.108613  0.314
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