Paul R. Kinchington - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Virology Biology, Microbiology Biology

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ouwendijk WJD, Roychoudhury P, Cunningham AL, Jerome KR, Koelle DM, Kinchington PR, Mohr I, Wilson AC, Verjans GGMGM, Depledge DP. Reanalysis of single-cell RNA sequencing data does not support herpes simplex virus 1 latency in non-neuronal ganglionic cells in mice. Journal of Virology. e0185823. PMID 38445887 DOI: 10.1128/jvi.01858-23  0.336
2023 Jürgens C, Ssebyatika G, Beyer S, Plückebaum N, Kropp KA, González-Motos V, Ritter B, Böning H, Nikolouli E, Kinchington PR, Lachmann N, Depledge DP, Krey T, Viejo-Borbolla A. Viral modulation of type II interferon increases T cell adhesion and virus spread. Biorxiv : the Preprint Server For Biology. PMID 37292914 DOI: 10.1101/2023.05.26.542397  0.364
2023 Matharu KS, Mammen A, Jhanji V, Kinchington PR, Kowalski RP. Double Trouble: An Unusual Keratitis Case of Herpes Simplex Virus and Varicella-Zoster Virus Co-infection. Cornea. PMID 37267471 DOI: 10.1097/ICO.0000000000003290  0.351
2023 McNulty J, Babu-Dokuburra C, Scattolon J, Zepeda-Velazquez C, Wesesky MA, Caldwell JK, Zheng W, Milosevic J, Kinchington PR, Bloom DC, Nimgaonkar VL, D'Aiuto L. Truncated ring-A amaryllidaceae alkaloid modulates the host cell integrated stress response, exhibiting antiviral activity to HSV-1 and SARSCoV-2. Scientific Reports. 13: 1639. PMID 36717567 DOI: 10.1038/s41598-023-28691-0  0.316
2022 D'Aiuto L, Caldwell JK, Wallace CT, Grams TR, Wesesky MA, Wood JA, Watkins SC, Kinchington PR, Bloom DC, Nimgaonkar VL. The Impaired Neurodevelopment of Human Neural Rosettes in HSV-1-Infected Early Brain Organoids. Cells. 11. PMID 36428968 DOI: 10.3390/cells11223539  0.318
2022 Bisht P, Das B, Borodianskiy-Shteinberg T, Kinchington PR, Goldstein RS. Studies of Infection and Experimental Reactivation by Recombinant VZV with Mutations in Virally-Encoded Small Non-Coding RNA. Viruses. 14. PMID 35632756 DOI: 10.3390/v14051015  0.384
2022 Lloyd MG, Yee MB, Flot JS, Liu D, Geiler BW, Kinchington PR, Moffat JF. Development of Robust Varicella Zoster Virus Luciferase Reporter Viruses for In Vivo Monitoring of Virus Growth and Its Antiviral Inhibition in Culture, Skin, and Humanized Mice. Viruses. 14. PMID 35458556 DOI: 10.3390/v14040826  0.315
2022 Zheng W, Benner EM, Bloom DC, Muralidaran V, Caldwell JK, Prabhudesai A, Piazza PA, Wood J, Kinchington PR, Nimgaonkar VL, D'Aiuto L. Variations in Aspects of Neural Precursor Cell Neurogenesis in a Human Model of HSV-1 Infection. Organogenesis. 18: 2055354. PMID 35384798 DOI: 10.1080/15476278.2022.2055354  0.311
2022 Wu BW, Yee MB, Goldstein RS, Kinchington PR. Antiviral Targeting of Varicella Zoster Virus Replication and Neuronal Reactivation Using CRISPR/Cas9 Cleavage of the Duplicated Open Reading Frames 62/71. Viruses. 14. PMID 35215971 DOI: 10.3390/v14020378  0.39
2021 Goldstein RS, Kinchington PR. Varicella Zoster Virus Neuronal Latency and Reactivation Modeled in Vitro. Current Topics in Microbiology and Immunology. PMID 34904194 DOI: 10.1007/82_2021_244  0.305
2021 Purohit SK, Samer C, McWilliam HEG, Traves R, Steain M, McSharry BP, Kinchington PR, Tscharke DC, Villadangos JA, Rossjohn J, Abendroth A, Slobedman B. Varicella zoster virus impairs expression of the non-classical major histocompatibility complex class I-related gene protein (MR1). The Journal of Infectious Diseases. PMID 34648018 DOI: 10.1093/infdis/jiab526  0.378
2021 St Leger AJ, Koelle DM, Kinchington PR, Verjans GMGM. Local Immune Control of Latent Herpes Simplex Virus Type 1 in Ganglia of Mice and Man. Frontiers in Immunology. 12: 723809. PMID 34603296 DOI: 10.3389/fimmu.2021.723809  0.35
2021 Warner BE, Yee MB, Zhang M, Hornung RS, Kaufer BB, Visalli RJ, Kramer PR, Goins WF, Kinchington PR. Varicella-zoster virus early infection but not complete replication is required for the induction of chronic hypersensitivity in rat models of postherpetic neuralgia. Plos Pathogens. 17: e1009689. PMID 34228767 DOI: 10.1371/journal.ppat.1009689  0.357
2020 Lloyd MG, Smith NA, Tighe M, Travis KL, Liu D, Upadhyaya PK, Kinchington PR, Chan GC, Moffat JF. A novel human skin tissue model to study varicella zoster virus and human cytomegalovirus. Journal of Virology. PMID 32878893 DOI: 10.1128/Jvi.01082-20  0.415
2020 Hornung R, Pritchard A, Kinchington PR, Kramer PR. Comparing Gene Expression in the Parabrachial and Amygdala of Diestrus and Proestrus Female Rats after Orofacial Varicella Zoster Injection. International Journal of Molecular Sciences. 21. PMID 32796585 DOI: 10.3390/Ijms21165749  0.311
2020 Hornung R, Pritchard A, Kinchington PR, Kramer PR. Reduced activity of GAD67 expressing cells in the reticular thalamus enhance thalamic excitatory activity and varicella zoster virus associated pain. Neuroscience Letters. 736: 135287. PMID 32763361 DOI: 10.1016/J.Neulet.2020.135287  0.346
2020 Zheng W, Klammer AM, Naciri JN, Yeung J, Demers M, Milosevich J, Kinchington PR, Bloom DC, Nimgaonkar VL, D'Aiuto L. Patterns of HSV-1 infection in neural progenitor cells. Journal of Virology. PMID 32493817 DOI: 10.1128/Jvi.00994-20  0.423
2020 Bisht P, Das B, Kinchington PR, Goldstein RS. VZVsncRNA antisense to the VZV latency-encoded transcript VLT enhance viral replication. Journal of Virology. PMID 32295909 DOI: 10.1128/Jvi.00123-20  0.491
2020 McSharry BP, Samer C, McWilliam HEG, Ashley CL, Yee MB, Steain M, Liu L, Fairlie DP, Kinchington PR, McCluskey J, Abendroth A, Villadangos JA, Rossjohn J, Slobedman B. Virus-Mediated Suppression of the Antigen Presentation Molecule MR1. Cell Reports. 30: 2948-2962.e4. PMID 32130899 DOI: 10.1016/J.Celrep.2020.02.017  0.431
2019 Treat BR, Bidula SM, St Leger AJ, Hendricks RL, Kinchington PR. Herpes Simplex Virus Type-1 specific CD8 T cell priming and latent ganglionic retention are shaped by viral epitope promoter kinetics. Journal of Virology. PMID 31826989 DOI: 10.1128/Jvi.01193-19  0.424
2019 Carroll KL, Avery L, Treat BR, Kane LP, Kinchington PR, Hendricks RL, St Leger AJ. Differential Expression of Immune Checkpoint Molecules on CD8 T Cells Specific for Immunodominant and Subdominant Herpes Simplex Virus 1 Epitopes. Journal of Virology. PMID 31645447 DOI: 10.1128/Jvi.01132-19  0.487
2019 Golani-Zaidie L, Borodiansky-Shteinberg T, Bisht P, Das B, Kinchington PR, Goldstein RS. Bioinformatically-predicted varicella zoster virus small non-coding RNAs are expressed in lytically-infected epithelial cells and neurons. Virus Research. 197773. PMID 31614167 DOI: 10.1016/J.Virusres.2019.197773  0.468
2019 Laemmle L, Goldstein RS, Kinchington PR. Modeling Varicella Zoster Virus Persistence and Reactivation - Closer to Resolving a Perplexing Persistent State. Frontiers in Microbiology. 10: 1634. PMID 31396173 DOI: 10.3389/Fmicb.2019.01634  0.443
2019 Stinson C, Logan SM, Bellinger LL, Rao M, Kinchington PR, Kramer PR. Estradiol Acts in Lateral Thalamic Region to Attenuate Varicella Zoster Virus Associated Affective Pain. Neuroscience. PMID 31271831 DOI: 10.1016/J.Neuroscience.2019.06.029  0.338
2019 D'Aiuto L, Bloom DC, Naciri JN, Smith A, Edwards TG, McClain L, Callio JA, Jessup M, Wood J, Chowdari K, Demers M, Abrahamson EE, Ikonomovic MD, Viggiano L, De Zio R, ... ... Kinchington PR, et al. Modeling HSV-1 infections in human CNS neuronal cells using two-dimensional and three- dimensional cultures derived from induced pluripotent stem cells. Journal of Virology. PMID 30787148 DOI: 10.1128/Jvi.00111-19  0.385
2018 Kramer PR, Rao M, Stinson C, Bellinger LL, Kinchington PR, Yee MB. Corrigendum: Aromatase Derived Estradiol Within the Thalamus Modulates Pain Induced by Varicella Zoster Virus. Frontiers in Integrative Neuroscience. 12: 66. PMID 30766482 DOI: 10.3389/Fnint.2018.00066  0.34
2018 D'Aiuto L, McNulty J, Hartline C, Demers M, Kalkeri R, Wood J, McClain L, Chattopadhyay A, Zhi Y, Naciri J, Smith A, Yolken R, Chowdari K, Zepeda-Velazquez C, Dokuburra CB, ... ... Kinchington P, et al. R430: A potent inhibitor of DNA and RNA viruses. Scientific Reports. 8: 16662. PMID 30413769 DOI: 10.1038/S41598-018-33904-Y  0.421
2018 Kramer P, Rao M, Stinson C, Bellinger LL, Kinchington PR, Yee MB. Aromatase Derived Estradiol Within the Thalamus Modulates Pain Induced by Varicella Zoster Virus. Frontiers in Integrative Neuroscience. 12: 46. PMID 30369871 DOI: 10.3389/Fnint.2018.00046  0.327
2018 D'Aiuto L, Naciri J, Radio N, Tekur S, Clayton D, Apodaca G, Di Maio R, Zhi Y, Dimitrion P, Piazza P, Demers M, Wood J, Chu C, Callio J, McClain L, ... ... Kinchington P, et al. Generation of three-dimensional human neuronal cultures: application to modeling CNS viral infections. Stem Cell Research & Therapy. 9: 134. PMID 29751846 DOI: 10.1186/S13287-018-0881-6  0.353
2017 Treat BR, Bidula SM, Ramachandran S, St Leger AJ, Hendricks RL, Kinchington PR. Influence of an immunodominant herpes simplex virus type 1 CD8+ T cell epitope on the target hierarchy and function of subdominant CD8+ T cells. Plos Pathogens. 13: e1006732. PMID 29206240 DOI: 10.1371/Journal.Ppat.1006732  0.609
2017 Kramer PR, Strand J, Stinson C, Bellinger LL, Kinchington PR, Yee MB, Umorin M, Peng YB. Role for the Ventral Posterior Medial/Posterior Lateral Thalamus and Anterior Cingulate Cortex in Affective/Motivation Pain Induced by Varicella Zoster Virus. Frontiers in Integrative Neuroscience. 11: 27. PMID 29089872 DOI: 10.3389/Fnint.2017.00027  0.314
2017 Markus A, Golani L, Ojha NK, Borodiansky-Shteinberg T, Kinchington PR, Goldstein RS. Varicella Zoster virus expresses multiple small non-coding RNAs. Journal of Virology. PMID 29021397 DOI: 10.1128/Jvi.01710-17  0.397
2017 Kramer P, Stinson C, Umorin M, Deng M, Rao M, Bellinger L, Yee MB, Kinchington PR. Lateral thalamic control of nociceptive response after whisker pad injection of varicella zoster virus. Neuroscience. PMID 28549561 DOI: 10.1016/J.Neuroscience.2017.05.030  0.333
2017 Stinson C, Deng M, Yee MB, Bellinger LL, Kinchington PR, Kramer PR. Sex differences underlying orofacial varicella zoster associated pain in rats. Bmc Neurology. 17: 95. PMID 28514943 DOI: 10.1186/S12883-017-0882-6  0.341
2017 D'Aiuto L, Williamson K, Dimitrion P, McNulty J, Brown CE, Dokuburra CB, Nielsen AJ, Lin WJ, Piazza P, Schurdak ME, Wood J, Yolken RH, Kinchington PR, Bloom DC, Nimgaonkar VL. Comparison of three cell-based drug screening platforms for HSV-1 infection. Antiviral Research. PMID 28342892 DOI: 10.1016/J.Antiviral.2017.03.016  0.378
2017 Tanaka M, Tashiro H, Omer B, Lapteva N, Ando J, Ngo M, Mehta B, Dotti G, Kinchington PR, Leen AM, Rossig C, Rooney CM. Vaccination targeting native receptors to enhance the function and proliferation of chimeric antigen receptor (CAR)-modified T cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28183713 DOI: 10.1158/1078-0432.Ccr-16-2138  0.322
2017 Rowe AM, Yun H, Treat BR, Kinchington PR, Hendricks RL. Subclinical Herpes Simplex Virus Type 1 Infections Provide Site-Specific Resistance to an Unrelated Pathogen. Journal of Immunology (Baltimore, Md. : 1950). PMID 28062697 DOI: 10.4049/Jimmunol.1601310  0.433
2016 McNulty J, D'Aiuto L, Zhi Y, McClain L, Zepeda-Velázquez C, Ler S, Jenkins HA, Yee MB, Piazza P, Yolken RH, Kinchington PR, Nimgaonkar VL. iPSC Neuronal Assay Identifies Amaryllidaceae Pharmacophore with Multiple Effects against Herpesvirus Infections. Acs Medicinal Chemistry Letters. 7: 46-50. PMID 26819664 DOI: 10.1021/Acsmedchemlett.5B00318  0.449
2015 McClain L, Zhi Y, Cheng H, Ghosh A, Piazza P, Yee MB, Kumar S, Milosevic J, Bloom DC, Arav-Boger R, Kinchington PR, Yolken R, Nimgaonkar V, D'Aiuto L. Broad-spectrum non-nucleoside inhibitors of human herpesviruses. Antiviral Research. 121: 16-23. PMID 26079681 DOI: 10.1016/J.Antiviral.2015.06.005  0.468
2015 Markus A, Lebenthal-Loinger I, Yang IH, Kinchington PR, Goldstein RS. An in vitro model of latency and reactivation of varicella zoster virus in human stem cell-derived neurons. Plos Pathogens. 11: e1004885. PMID 26042814 DOI: 10.1371/Journal.Ppat.1004885  0.475
2015 Grigoryan S, Yee MB, Glick Y, Gerber D, Kepten E, Garini Y, Yang IH, Kinchington PR, Goldstein RS. Direct transfer of viral and cellular proteins from varicella-zoster virus-infected non-neuronal cells to human axons. Plos One. 10: e0126081. PMID 25973990 DOI: 10.1371/Journal.Pone.0126081  0.445
2015 Guedon JM, Wu S, Zheng X, Churchill CC, Glorioso JC, Liu CH, Liu S, Vulchanova L, Bekker A, Tao YX, Kinchington PR, Goins WF, Fairbanks CA, Hao S. Current gene therapy using viral vectors for chronic pain. Molecular Pain. 11: 27. PMID 25962909 DOI: 10.1186/S12990-015-0018-1  0.305
2015 Guedon JM, Yee MB, Zhang M, Harvey SA, Goins WF, Kinchington PR. Neuronal changes induced by Varicella Zoster Virus in a rat model of postherpetic neuralgia. Virology. 482: 167-80. PMID 25880108 DOI: 10.1016/J.Virol.2015.03.046  0.424
2015 Bayer A, Delorme-Axford E, Sleigher C, Frey TK, Trobaugh DW, Klimstra WB, Emert-Sedlak LA, Smithgall TE, Kinchington PR, Vadia S, Seveau S, Boyle JP, Coyne CB, Sadovsky Y. Human trophoblasts confer resistance to viruses implicated in perinatal infection. American Journal of Obstetrics and Gynecology. 212: 71.e1-8. PMID 25108145 DOI: 10.1016/J.Ajog.2014.07.060  0.411
2015 D'Aiuto L, Prasad KM, Upton CH, Viggiano L, Milosevic J, Raimondi G, McClain L, Chowdari K, Tischfield J, Sheldon M, Moore JC, Yolken RH, Kinchington PR, Nimgaonkar VL. Persistent infection by HSV-1 is associated with changes in functional architecture of iPSC-derived neurons and brain activation patterns underlying working memory performance. Schizophrenia Bulletin. 41: 123-32. PMID 24622295 DOI: 10.1093/Schbul/Sbu032  0.394
2015 Goins WF, Doyal M, Guedon JG, Marzulli M, Huang S, Kinchington PR, Cohen JB, Glorioso JC. 497. HSV Vector-Mediated Expression of a Novel Drug Activated Pain Signalling Therapeutic Abrogates Pain Molecular Therapy. 23: S198. DOI: 10.1016/S1525-0016(16)34106-5  0.327
2014 Guedon JM, Zhang M, Glorioso JC, Goins WF, Kinchington PR. Relief of pain induced by varicella-zoster virus in a rat model of post-herpetic neuralgia using a herpes simplex virus vector expressing enkephalin. Gene Therapy. 21: 694-702. PMID 24830437 DOI: 10.1038/Gt.2014.43  0.353
2014 Markus A, Waldman Ben-Asher H, Kinchington PR, Goldstein RS. Cellular transcriptome analysis reveals differential expression of pro- and antiapoptosis genes by varicella-zoster virus-infected neurons and fibroblasts. Journal of Virology. 88: 7674-7. PMID 24741086 DOI: 10.1128/Jvi.00500-14  0.448
2014 Sloutskin A, Yee MB, Kinchington PR, Goldstein RS. Varicella-zoster virus and herpes simplex virus 1 can infect and replicate in the same neurons whether co- or superinfected. Journal of Virology. 88: 5079-86. PMID 24574392 DOI: 10.1128/Jvi.00252-14  0.505
2014 Jones M, Dry IR, Frampton D, Singh M, Kanda RK, Yee MB, Kellam P, Hollinshead M, Kinchington PR, O'Toole EA, Breuer J. RNA-seq analysis of host and viral gene expression highlights interaction between varicella zoster virus and keratinocyte differentiation. Plos Pathogens. 10: e1003896. PMID 24497829 DOI: 10.1371/Journal.Ppat.1003896  0.449
2014 Kinchington PR. Targeting host pathways to block HSV-1 at the cornea. Investigative Ophthalmology & Visual Science. 55: 716. PMID 24492207 DOI: 10.1167/Iovs.14-13879  0.496
2013 Sloutskin A, Kinchington PR, Goldstein RS. Productive vs non-productive infection by cell-free varicella zoster virus of human neurons derived from embryonic stem cells is dependent upon infectious viral dose. Virology. 443: 285-93. PMID 23769240 DOI: 10.1016/J.Virol.2013.05.021  0.463
2013 Ramachandran S, Knickelbein JE, Ferko C, Hendricks RL, Kinchington PR. Corrigendum to "Development and pathogenic evaluation of recombinant herpes simplex virus type 1 expressing two fluorescent reporter genes from different lytic promoters" [Virology 378 (2008) 254-264] Virology. 435: 504. DOI: 10.1016/J.Virol.2012.10.014  0.632
2012 Swamynathan S, Buela KA, Kinchington P, Lathrop KL, Misawa H, Hendricks RL, Swamynathan SK. Klf4 regulates the expression of Slurp1, which functions as an immunomodulatory peptide in the mouse cornea. Investigative Ophthalmology & Visual Science. 53: 8433-46. PMID 23139280 DOI: 10.1167/Iovs.12-10759  0.303
2012 Grigoryan S, Kinchington PR, Yang IH, Selariu A, Zhu H, Yee M, Goldstein RS. Retrograde axonal transport of VZV: kinetic studies in hESC-derived neurons. Journal of Neurovirology. 18: 462-70. PMID 22918852 DOI: 10.1007/S13365-012-0124-Z  0.371
2012 Kinchington PR, Leger AJ, Guedon JM, Hendricks RL. Herpes simplex virus and varicella zoster virus, the house guests who never leave. Herpesviridae. 3: 5. PMID 22691604 DOI: 10.1186/2042-4280-3-5  0.473
2012 Dukhovny A, Sloutskin A, Markus A, Yee MB, Kinchington PR, Goldstein RS. Varicella-zoster virus infects human embryonic stem cell-derived neurons and neurospheres but not pluripotent embryonic stem cells or early progenitors. Journal of Virology. 86: 3211-8. PMID 22238301 DOI: 10.1128/Jvi.06810-11  0.434
2012 Sloan E, Henriquez R, Kinchington PR, Slobedman B, Abendroth A. Varicella-zoster virus inhibition of the NF-κB pathway during infection of human dendritic cells: role for open reading frame 61 as a modulator of NF-κB activity. Journal of Virology. 86: 1193-202. PMID 22090112 DOI: 10.1128/Jvi.06400-11  0.388
2011 Kinchington PR, Goins WF. Varicella zoster virus-induced pain and post-herpetic neuralgia in the human host and in rodent animal models. Journal of Neurovirology. 17: 590-9. PMID 22205584 DOI: 10.1007/S13365-011-0069-7  0.329
2011 Markus A, Grigoryan S, Sloutskin A, Yee MB, Zhu H, Yang IH, Thakor NV, Sarid R, Kinchington PR, Goldstein RS. Varicella-zoster virus (VZV) infection of neurons derived from human embryonic stem cells: direct demonstration of axonal infection, transport of VZV, and productive neuronal infection. Journal of Virology. 85: 6220-33. PMID 21525353 DOI: 10.1128/Jvi.02396-10  0.431
2011 Bertke AS, Swanson SM, Chen J, Imai Y, Kinchington PR, Margolis TP. A5-positive primary sensory neurons are nonpermissive for productive infection with herpes simplex virus 1 in vitro. Journal of Virology. 85: 6669-77. PMID 21507969 DOI: 10.1128/Jvi.00204-11  0.429
2011 Verweij MC, Lipinska AD, Koppers-Lalic D, van Leeuwen WF, Cohen JI, Kinchington PR, Messaoudi I, Bienkowska-Szewczyk K, Ressing ME, Rijsewijk FA, Wiertz EJ. The capacity of UL49.5 proteins to inhibit TAP is widely distributed among members of the genus Varicellovirus. Journal of Virology. 85: 2351-63. PMID 21159875 DOI: 10.1128/Jvi.01621-10  0.466
2011 Erazo A, Yee MB, Banfield BW, Kinchington PR. The alphaherpesvirus US3/ORF66 protein kinases direct phosphorylation of the nuclear matrix protein matrin 3. Journal of Virology. 85: 568-81. PMID 20962082 DOI: 10.1128/Jvi.01611-10  0.747
2010 Walters MS, Kinchington PR, Banfield BW, Silverstein S. Hyperphosphorylation of histone deacetylase 2 by alphaherpesvirus US3 kinases. Journal of Virology. 84: 9666-76. PMID 20660201 DOI: 10.1128/Jvi.00981-10  0.513
2010 Ramachandran S, Davoli KA, Yee MB, Hendricks RL, Kinchington PR. Delaying the expression of herpes simplex virus type 1 glycoprotein B (gB) to a true late gene alters neurovirulence and inhibits the gB-CD8+ T-cell response in the trigeminal ganglion. Journal of Virology. 84: 8811-20. PMID 20573821 DOI: 10.1128/Jvi.00496-10  0.652
2010 Abendroth A, Kinchington PR, Slobedman B. Varicella zoster virus immune evasion strategies. Current Topics in Microbiology and Immunology. 342: 155-71. PMID 20563710 DOI: 10.1007/82_2010_41  0.441
2010 Erazo A, Kinchington PR. Varicella-zoster virus open reading frame 66 protein kinase and its relationship to alphaherpesvirus US3 kinases. Current Topics in Microbiology and Immunology. 342: 79-98. PMID 20186610 DOI: 10.1007/82_2009_7  0.724
2009 Walters MS, Erazo A, Kinchington PR, Silverstein S. Histone deacetylases 1 and 2 are phosphorylated at novel sites during varicella-zoster virus infection. Journal of Virology. 83: 11502-13. PMID 19740981 DOI: 10.1128/Jvi.01318-09  0.75
2008 Knickelbein JE, Khanna KM, Yee MB, Baty CJ, Kinchington PR, Hendricks RL. Noncytotoxic lytic granule-mediated CD8+ T cell inhibition of HSV-1 reactivation from neuronal latency. Science (New York, N.Y.). 322: 268-71. PMID 18845757 DOI: 10.1126/Science.1164164  0.445
2008 Leisenfelder SA, Kinchington PR, Moffat JF. Cyclin-dependent kinase 1/cyclin B1 phosphorylates varicella-zoster virus IE62 and is incorporated into virions. Journal of Virology. 82: 12116-25. PMID 18799590 DOI: 10.1128/Jvi.00153-08  0.493
2008 Ramachandran S, Knickelbein JE, Ferko C, Hendricks RL, Kinchington PR. Development and pathogenic evaluation of recombinant herpes simplex virus type 1 expressing two fluorescent reporter genes from different lytic promoters. Virology. 378: 254-64. PMID 18619637 DOI: 10.1016/J.Virol.2008.05.034  0.682
2008 Erazo A, Yee MB, Osterrieder N, Kinchington PR. Varicella-zoster virus open reading frame 66 protein kinase is required for efficient viral growth in primary human corneal stromal fibroblast cells. Journal of Virology. 82: 7653-65. PMID 18495764 DOI: 10.1128/Jvi.00311-08  0.757
2007 Milikan JC, Kinchington PR, Baarsma GS, Kuijpers RW, Osterhaus AD, Verjans GM. Identification of viral antigens recognized by ocular infiltrating T cells from patients with varicella zoster virus-induced uveitis. Investigative Ophthalmology & Visual Science. 48: 3689-97. PMID 17652740 DOI: 10.1167/Iovs.07-0020  0.395
2007 Ramachandran S, Kinchington PR. Potential prophylactic and therapeutic vaccines for HSV infections. Current Pharmaceutical Design. 13: 1965-73. PMID 17627530 DOI: 10.2174/138161207781039760  0.604
2007 Eisfeld AJ, Yee MB, Erazo A, Abendroth A, Kinchington PR. Downregulation of class I major histocompatibility complex surface expression by varicella-zoster virus involves open reading frame 66 protein kinase-dependent and -independent mechanisms. Journal of Virology. 81: 9034-49. PMID 17567702 DOI: 10.1128/Jvi.00711-07  0.758
2007 Verjans GM, Hintzen RQ, van Dun JM, Poot A, Milikan JC, Laman JD, Langerak AW, Kinchington PR, Osterhaus AD. Selective retention of herpes simplex virus-specific T cells in latently infected human trigeminal ganglia. Proceedings of the National Academy of Sciences of the United States of America. 104: 3496-501. PMID 17360672 DOI: 10.1073/Pnas.0610847104  0.448
2007 Hasnie FS, Breuer J, Parker S, Wallace V, Blackbeard J, Lever I, Kinchington PR, Dickenson AH, Pheby T, Rice AS. Further characterization of a rat model of varicella zoster virus-associated pain: Relationship between mechanical hypersensitivity and anxiety-related behavior, and the influence of analgesic drugs. Neuroscience. 144: 1495-508. PMID 17197105 DOI: 10.1016/J.Neuroscience.2006.11.029  0.366
2006 Kowalski RP, Thompson PP, Kinchington PR, Gordon YJ. Evaluation of the SmartCycler II system for real-time detection of viruses and Chlamydia from ocular specimens. Archives of Ophthalmology (Chicago, Ill. : 1960). 124: 1135-9. PMID 16908816 DOI: 10.1001/Archopht.124.8.1135  0.316
2006 Eisfeld AJ, Turse SE, Jackson SA, Lerner EC, Kinchington PR. Phosphorylation of the varicella-zoster virus (VZV) major transcriptional regulatory protein IE62 by the VZV open reading frame 66 protein kinase. Journal of Virology. 80: 1710-23. PMID 16439528 DOI: 10.1128/Jvi.80.4.1710-1723.2006  0.476
2006 Hood C, Cunningham AL, Slobedman B, Arvin AM, Sommer MH, Kinchington PR, Abendroth A. Varicella-zoster virus ORF63 inhibits apoptosis of primary human neurons. Journal of Virology. 80: 1025-31. PMID 16379003 DOI: 10.1128/Jvi.80.2.1025-1031.2006  0.461
2006 Biswas PS, Banerjee K, Kinchington PR, Rouse BT. Involvement of IL-6 in the paracrine production of VEGF in ocular HSV-1 infection. Experimental Eye Research. 82: 46-54. PMID 16009363 DOI: 10.1016/J.Exer.2005.05.001  0.36
2005 Prabhakaran K, Sheridan BS, Kinchington PR, Khanna KM, Decman V, Lathrop K, Hendricks RL. Sensory neurons regulate the effector functions of CD8+ T cells in controlling HSV-1 latency ex vivo. Immunity. 23: 515-25. PMID 16286019 DOI: 10.1016/J.Immuni.2005.09.017  0.38
2005 Garry EM, Delaney A, Anderson HA, Sirinathsinghji EC, Clapp RH, Martin WJ, Kinchington PR, Krah DL, Abbadie C, Fleetwood-Walker SM. Varicella zoster virus induces neuropathic changes in rat dorsal root ganglia and behavioral reflex sensitisation that is attenuated by gabapentin or sodium channel blocking drugs. Pain. 118: 97-111. PMID 16213091 DOI: 10.1016/J.Pain.2005.08.003  0.424
2005 Decman V, Freeman ML, Kinchington PR, Hendricks RL. Immune control of HSV-1 latency. Viral Immunology. 18: 466-73. PMID 16212525 DOI: 10.1089/Vim.2005.18.466  0.471
2005 Biswas PS, Banerjee K, Kim B, Kinchington PR, Rouse BT. Role of inflammatory cytokine-induced cyclooxygenase 2 in the ocular immunopathologic disease herpetic stromal keratitis. Journal of Virology. 79: 10589-600. PMID 16051851 DOI: 10.1128/Jvi.79.16.10589-10600.2005  0.411
2005 Decman V, Kinchington PR, Harvey SA, Hendricks RL. Gamma interferon can block herpes simplex virus type 1 reactivation from latency, even in the presence of late gene expression. Journal of Virology. 79: 10339-47. PMID 16051826 DOI: 10.1128/Jvi.79.16.10339-10347.2005  0.482
2005 Kinchington PR, Romanowski EG, Jerold Gordon Y. Prospects for adenovirus antivirals. The Journal of Antimicrobial Chemotherapy. 55: 424-9. PMID 15743895 DOI: 10.1093/Jac/Dki057  0.3
2004 Romanowski EG, Bartels SP, Vogel R, Wetherall NT, Hodges-Savola C, Kowalski RP, Yates KA, Kinchington PR, Gordon YJ. Feasibility of an antiviral clinical trial requiring cross-country shipment of conjunctival adenovirus cultures and recovery of infectious virus. Current Eye Research. 29: 195-9. PMID 15512967 DOI: 10.1080/02713680490504830  0.325
2004 Taylor SL, Kinchington PR, Brooks A, Moffat JF. Roscovitine, a cyclin-dependent kinase inhibitor, prevents replication of varicella-zoster virus. Journal of Virology. 78: 2853-62. PMID 14990704 DOI: 10.1128/Jvi.78.6.2853-2862.2004  0.458
2003 Cohrs RJ, Gilden DH, Kinchington PR, Grinfeld E, Kennedy PG. Varicella-zoster virus gene 66 transcription and translation in latently infected human Ganglia. Journal of Virology. 77: 6660-5. PMID 12767985 DOI: 10.1128/Jvi.77.12.6660-6665.2003  0.49
2003 Khanna KM, Bonneau RH, Kinchington PR, Hendricks RL. Herpes simplex virus-specific memory CD8+ T cells are selectively activated and retained in latently infected sensory ganglia. Immunity. 18: 593-603. PMID 12753737 DOI: 10.1016/S1074-7613(03)00112-2  0.435
2002 Arvin AM, Sharp M, Moir M, Kinchington PR, Sadeghi-Zadeh M, Ruyechan WT, Hay J. Memory cytotoxic T cell responses to viral tegument and regulatory proteins encoded by open reading frames 4, 10, 29, and 62 of varicella-zoster virus. Viral Immunology. 15: 507-16. PMID 12479399 DOI: 10.1089/088282402760312377  0.456
2001 Kinchington PR, Fite K, Seman A, Turse SE. Virion association of IE62, the varicella-zoster virus (VZV) major transcriptional regulatory protein, requires expression of the VZV open reading frame 66 protein kinase. Journal of Virology. 75: 9106-13. PMID 11533174 DOI: 10.1128/Jvi.75.19.9106-9113.2001  0.519
2000 Kinchington PR, Fite K, Turse SE. Nuclear accumulation of IE62, the varicella-zoster virus (VZV) major transcriptional regulatory protein, is inhibited by phosphorylation mediated by the VZV open reading frame 66 protein kinase. Journal of Virology. 74: 2265-77. PMID 10666257 DOI: 10.1128/Jvi.74.5.2265-2277.2000  0.521
1999 Kinchington PR. Latency of varicella zoster virus; a persistently perplexing state. Frontiers in Bioscience : a Journal and Virtual Library. 4: D200-11. PMID 9989948 DOI: 10.2741/Kinchington  0.383
1998 Michael EJ, Kuck KM, Kinchington PR. Anatomy of the varicella-zoster virus open-reading frame 4 promoter. The Journal of Infectious Diseases. S27-33. PMID 9852969 DOI: 10.1086/514273  0.388
1998 Kinchington PR, Turse SE. Regulated nuclear localization of the varicella-zoster virus major regulatory protein, IE62. The Journal of Infectious Diseases. S16-21. PMID 9852967 DOI: 10.1086/514263  0.464
1998 Moffat JF, Zerboni L, Kinchington PR, Grose C, Kaneshima H, Arvin AM. Attenuation of the Vaccine Oka Strain of Varicella-Zoster Virus and Role of Glycoprotein C in Alphaherpesvirus Virulence Demonstrated in the SCID-hu Mouse Journal of Virology. 72: 965-974. DOI: 10.1128/Jvi.72.2.965-974.1998  0.425
1997 Lowry PW, Koropchak CM, Choi CYH, Mocarski ES, Kern ER, Kinchington PR, Arvin AM. The synthesis and immunogenicity of varicella-zoster virus glycoprotein E and immediate-early protein (IE62) expressed in recombinant herpes simplex virus-1 Antiviral Research. 33: 187-200. PMID 9037375 DOI: 10.1016/S0166-3542(96)01014-5  0.491
1996 Kinchington PR, Vergnes JP, Turse SE. Transcriptional mapping of varicella-zoster virus regulatory proteins. Neurology. 45: S33-5. PMID 8545015 DOI: 10.1212/Wnl.45.12_Suppl_8.S33  0.411
1996 Gordon YJ, Romanowski EG, Araullo-Cruz T, Kinchington PR. The proportion of trigeminal ganglionic neurons expressing herpes simplex virus type 1 latency-associated transcripts correlates to reactivation in the New Zealand rabbit ocular model. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. 233: 649-54. PMID 8529909 DOI: 10.1007/Bf00185286  0.412
1995 Schmitz JB, Albright AG, Kinchington PR, Jenkins FJ. The UL37 protein of herpes simplex virus type 1 is associated with the tegument of purified virions. Virology. 206: 1055-65. PMID 7856080 DOI: 10.1006/Viro.1995.1028  0.518
1995 Kinchington PR, Bookey D, Turse SE. The transcriptional regulatory proteins encoded by varicella-zoster virus open reading frames (ORFs) 4 and 63, but not ORF 61, are associated with purified virus particles. Journal of Virology. 69: 4274-82. PMID 7769688 DOI: 10.1128/Jvi.69.7.4274-4282.1995  0.49
1994 Kinchington PR, Vergnes JP, Defechereux P, Piette J, Turse SE. Transcriptional mapping of the varicella-zoster virus regulatory genes encoding open reading frames 4 and 63. Journal of Virology. 68: 3570-81. PMID 8189496 DOI: 10.1128/Jvi.68.6.3570-3581.1994  0.368
1994 Ng T, Keenan L, Kinchington PR, Grose C. Phosphorylation of varicella-zoster virus open reading frame (ORF) 62 regulatory product by viral ORF 47-associated protein kinase Journal of Virology. 68: 1350-1359. PMID 8107200 DOI: 10.1128/Jvi.68.3.1350-1359.1994  0.463
1994 Maheshwari RK, Sidhu GS, Singh AK, Sivaram SS, Kinchington PR, Hay J, Friedman RM. Defective transport of herpes simplex virus glycoprotein in interferon-treated cells: role of intracellular pH. Journal of Interferon Research. 14: 319-24. PMID 7897250 DOI: 10.1089/Jir.1994.14.319  0.408
1994 Perera LP, Kaushal S, Kinchington PR, Mosca JD, Hayward GS, Straus SE. Varicella-zoster virus open reading frame 4 encodes a transcriptional activator that is functionally distinct from that of herpes simplex virus homology ICP27. Journal of Virology. 68: 2468-2477. DOI: 10.1128/Jvi.68.4.2468-2477.1994  0.451
1993 Sabella C, Lowry PW, Abbruzzi GM, Koropchak CM, Kinchington PR, Sadegh-Zadeh M, Hay J, Ruyechan WT, Arvin AM. Immunization with the immediate-early tegument protein (open reading frame 62) of varicella-zoster virus protects guinea pigs against virus challenge Journal of Virology. 67: 7673-7676. PMID 8230489 DOI: 10.1128/Jvi.67.12.7673-7676.1993  0.434
1992 Lowry PW, Solem S, Watson BN, Koropchak CM, Thackray HM, Kinchington PR, Ruyechan WT, Ling P, Hay J, Arvin AM. Immunity in strain 2 guinea-pigs inoculated with vaccinia virus recombinants expressing varicella-zoster virus glycoproteins I, IV, V or the protein product of the immediate early gene 62 Journal of General Virology. 73: 811-819. PMID 1321876 DOI: 10.1099/0022-1317-73-4-811  0.427
1992 Ling P, Kinchington PR, Sadeghi-Zadeh M, Ruyechan WT, Hayh J. Transcription from varicella-zoster virus gene 67 (glycoprotein IV) Journal of Virology. 66: 3690-3698. PMID 1316476 DOI: 10.1128/Jvi.66.6.3690-3698.1992  0.352
1992 Kinchington PR, Hougland JK, Arvin AM, Ruyechan WT, Hay J. The varicella-zoster virus immediate-early protein IE62 is a major component of virus particles Journal of Virology. 66: 359-366. PMID 1309252 DOI: 10.1128/Jvi.66.1.359-366.1992  0.402
1988 Felser JM, Kinchington PR, Inchauspe G, Straus SE, Ostrove JM. Cell lines containing varicella-zoster virus open reading frame 62 and expressing the "IE" 175 protein complement ICP4 mutants of herpes simplex virus type 1. Journal of Virology. 62: 2076-82. PMID 2835512 DOI: 10.1128/jvi.62.6.2076-2082.1988  0.387
1985 Snowden BW, Kinchington PR, Powell KL, Halliburton IW. Antigenic and biochemical analysis of gB of herpes simplex virus type 1 and type 2 and of cross-reacting glycoproteins induced by bovine mammillitis virus and equine herpesvirus type 1. The Journal of General Virology. 231-47. PMID 2981966 DOI: 10.1099/0022-1317-66-2-231  0.464
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