Takashi Yamamoto, Ph.D. - Publications

Affiliations: 
2004 University of Hawai'i at Manoa, Honolulu, HI 
Area:
General Economics, Labor Economics

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yasumoto S, Umemoto N, Lee HJ, Nakayasu M, Sawai S, Sakuma T, Yamamoto T, Mizutani M, Saito K, Muranaka T. Efficient genome engineering using Platinum TALEN in potato. Plant Biotechnology (Tokyo, Japan). 36: 167-173. PMID 31768118 DOI: 10.5511/plantbiotechnology.19.0805a  0.4
2019 Tajima Y, Hozumi A, Yoshida K, Treen N, Sakuma T, Yamamoto T, Sasakura Y. Hox13 is essential for formation of a sensory organ at the terminal end of the sperm duct in Ciona. Developmental Biology. PMID 31682808 DOI: 10.1016/j.ydbio.2019.10.028  0.4
2019 Higuchi K, Kazeto Y, Ozaki Y, Yamaguchi T, Shimada Y, Ina Y, Soma S, Sakakura Y, Goto R, Matsubara T, Nishiki I, Iwasaki Y, Yasuike M, Nakamura Y, Matsuura A, ... ... Yamamoto T, et al. Targeted mutagenesis of the ryanodine receptor by Platinum TALENs causes slow swimming behaviour in Pacific bluefin tuna (Thunnus orientalis). Scientific Reports. 9: 13871. PMID 31554877 DOI: 10.1038/s41598-019-50418-3  0.4
2019 Suenaga Y, Yamamoto M, Sakuma T, Sasada M, Fukai F, Ohira M, Yamaguchi Y, Yamamoto T, Ando K, Ozaki T, Nakagawara A. TAp63 represses transcription of MYCN/NCYM gene and its high levels of expression are associated with favorable outcome in neuroblastoma. Biochemical and Biophysical Research Communications. PMID 31427086 DOI: 10.1016/j.bbrc.2019.08.052  0.4
2019 Tanigawa S, Naganuma H, Kaku Y, Era T, Sakuma T, Yamamoto T, Taguchi A, Nishinakamura R. Activin Is Superior to BMP7 for Efficient Maintenance of Human iPSC-Derived Nephron Progenitors. Stem Cell Reports. PMID 31378669 DOI: 10.1016/j.stemcr.2019.07.003  0.4
2019 Liu D, Awazu A, Sakuma T, Yamamoto T, Sakamoto N. Establishment of knockout adult sea urchins by using a CRISPR-Cas9 system. Development, Growth & Differentiation. PMID 31359433 DOI: 10.1111/dgd.12624  0.4
2019 Konishi S, Tanaka N, Mashimo T, Yamamoto T, Sakuma T, Kaneko T, Tanaka M, Izawa T, Yamate J, Kuwamura M. Pathological characteristics of Ccdc85c knockout rats: a rat model of genetic hydrocephalus. Experimental Animals. PMID 31341137 DOI: 10.1538/expanim.19-0005  0.4
2019 Watanabe M, Nakano K, Uchikura A, Matsunari H, Yashima S, Umeyama K, Takayanagi S, Sakuma T, Yamamoto T, Morita S, Horii T, Hatada I, Nishinakamura R, Nakauchi H, Nagashima H. Anephrogenic phenotype induced by SALL1 gene knockout in pigs. Scientific Reports. 9: 8016. PMID 31142767 DOI: 10.1038/s41598-019-44387-w  0.4
2019 Kohara H, Utsugisawa T, Sakamoto C, Hirose L, Ogawa Y, Ogura H, Sugawara A, Aoki T, Iwasaki T, Asai T, Doisaki S, Okuno Y, Muramatsu H, Abe T, Kurita R, ... ... Yamamoto T, et al. KLF1 Mutation E325K Induces Cell-cycle Arrest in Erythroid Cells Differentiated from Congenital Dyserythropoietic Anemia (CDA) Patient-specific Induced Pluripotent Stem Cells. Experimental Hematology. PMID 30876823 DOI: 10.1016/j.exphem.2019.03.001  0.4
2019 Takimoto A, Kokubu C, Watanabe H, Sakuma T, Yamamoto T, Kondoh G, Hiraki Y, Shukunami C. Differential transactivation of the upstream aggrecan enhancer regulated by PAX1/9 depends on SOX9-driven transactivation. Scientific Reports. 9: 4605. PMID 30872687 DOI: 10.1038/s41598-019-40810-4  0.4
2019 Tsuda M, Ogawa S, Ooka M, Kobayashi K, Hirota K, Wakasugi M, Matsunaga T, Sakuma T, Yamamoto T, Chikuma S, Sasanuma H, Debatisse M, Doherty AJ, Fuchs RP, Takeda S. PDIP38/PolDIP2 controls the DNA damage tolerance pathways by increasing the relative usage of translesion DNA synthesis over template switching. Plos One. 14: e0213383. PMID 30840704 DOI: 10.1371/journal.pone.0213383  0.4
2019 Kazuki Y, Kobayashi K, Hirabayashi M, Abe S, Kajitani N, Kazuki K, Takehara S, Takiguchi M, Satoh D, Kuze J, Sakuma T, Kaneko T, Mashimo T, Osamura M, Hashimoto M, ... ... Yamamoto T, et al. Humanized UGT2 and CYP3A transchromosomic rats for improved prediction of human drug metabolism. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718425 DOI: 10.1073/pnas.1808255116  0.4
2018 Kunii A, Hara Y, Takenaga M, Hattori N, Fukazawa T, Ushijima T, Yamamoto T, Sakuma T. Three-Component Repurposed Technology for Enhanced Expression: Highly Accumulable Transcriptional Activators via Branched Tag Arrays. The Crispr Journal. 1: 337-347. PMID 31021277 DOI: 10.1089/crispr.2018.0009  0.4
2018 Nishitani A, Kunisawa N, Sugimura T, Sato K, Yoshida Y, Suzuki T, Sakuma T, Yamamoto T, Asano M, Saito Y, Ohno Y, Kuramoto T. Loss of HCN1 subunits causes absence epilepsy in rats. Brain Research. PMID 30408474 DOI: 10.1016/j.brainres.2018.11.004  0.4
2018 Miao W, Sakai K, Imamura R, Ito K, Suga H, Sakuma T, Yamamoto T, Matsumoto K. MET Activation by a Macrocyclic Peptide Agonist that Couples to Biological Responses Differently from HGF in a Context-Dependent Manner. International Journal of Molecular Sciences. 19. PMID 30322054 DOI: 10.3390/ijms19103141  0.4
2018 Sakuma T, Yamamoto T. Acceleration of cancer science with genome editing and related technologies. Cancer Science. PMID 30315615 DOI: 10.1111/cas.13832  0.4
2018 Deguchi Y, Nishina T, Asano K, Ohmuraya M, Nakagawa Y, Nakagata N, Sakuma T, Yamamoto T, Araki K, Mikami T, Tanaka M, Nakano H. Generation of and characterization of anti-IL-11 antibodies using newly established Il11-deficient mice. Biochemical and Biophysical Research Communications. PMID 30268501 DOI: 10.1016/j.bbrc.2018.09.128  0.4
2018 Tanigawa S, Islam M, Sharmin S, Naganuma H, Yoshimura Y, Haque F, Era T, Nakazato H, Nakanishi K, Sakuma T, Yamamoto T, Kurihara H, Taguchi A, Nishinakamura R. Organoids from Nephrotic Disease-Derived iPSCs Identify Impaired NEPHRIN Localization and Slit Diaphragm Formation in Kidney Podocytes. Stem Cell Reports. PMID 30174315 DOI: 10.1016/j.stemcr.2018.08.003  0.4
2018 Nakade S, Mochida K, Kunii A, Nakamae K, Aida T, Tanaka K, Sakamoto N, Sakuma T, Yamamoto T. Biased genome editing using the local accumulation of DSB repair molecules system. Nature Communications. 9: 3270. PMID 30115916 DOI: 10.1038/s41467-018-05773-6  0.4
2018 Harata A, Hirakawa M, Sakuma T, Yamamoto T, Hashimoto C. Nucleotide receptor P2RY4 is required for head formation via induction and maintenance of head organizer in Xenopus laevis. Development, Growth & Differentiation. PMID 30069871 DOI: 10.1111/dgd.12563  0.4
2018 Yoshida M, Yokota E, Sakuma T, Yamatsuji T, Takigawa N, Ushijima T, Yamamoto T, Fukazawa T, Naomoto Y. Development of an integrated CRISPRi targeting ΔNp63 for treatment of squamous cell carcinoma. Oncotarget. 9: 29220-29232. PMID 30018747 DOI: 10.18632/oncotarget.25678  0.4
2018 Nakagawa Y, Sakuma T, Takeo T, Nakagata N, Yamamoto T. Electroporation-mediated genome editing in vitrified/warmed mouse zygotes created by IVF via ultra-superovulation. Experimental Animals. PMID 30012936 DOI: 10.1538/expanim.18-0062  0.4
2018 Saha LK, Kim S, Kang H, Akter S, Choi K, Sakuma T, Yamamoto T, Sasanuma H, Hirota K, Nakamura J, Honma M, Takeda S, Dertinger S. Differential micronucleus frequency in isogenic human cells deficient in DNA repair pathways is a valuable indicator for evaluating genotoxic agents and their genotoxic mechanisms. Environmental and Molecular Mutagenesis. PMID 29761828 DOI: 10.1002/em.22201  0.4
2018 Takashina T, Koyama T, Nohara S, Hasegawa M, Ishiguro A, Iijima K, Lu J, Shimura M, Okamura T, Sakuma T, Yamamoto T, Ishizaka Y. Identification of a cell-penetrating peptide applicable to a protein-based transcription activator-like effector expression system for cell engineering. Biomaterials. 173: 11-21. PMID 29734017 DOI: 10.1016/j.biomaterials.2018.04.040  0.4
2018 Kuriyama S, Tsuji T, Sakuma T, Yamamoto T, Tanaka M. PLEKHN1 promotes apoptosis by enhancing Bax-Bak hetro-oligomerization through interaction with Bid in human colon cancer. Cell Death Discovery. 4: 11. PMID 29531808 DOI: 10.1038/s41420-017-0006-5  0.4
2018 Kim SI, Matsumoto T, Kagawa H, Nakamura M, Hirohata R, Ueno A, Ohishi M, Sakuma T, Soga T, Yamamoto T, Woltjen K. Microhomology-assisted scarless genome editing in human iPSCs. Nature Communications. 9: 939. PMID 29507284 DOI: 10.1038/s41467-018-03044-y  0.4
2018 Shukunami C, Takimoto A, Nishizaki Y, Yoshimoto Y, Tanaka S, Miura S, Watanabe H, Sakuma T, Yamamoto T, Kondoh G, Hiraki Y. Scleraxis is a transcriptional activator that regulates the expression of Tenomodulin, a marker of mature tenocytes and ligamentocytes. Scientific Reports. 8: 3155. PMID 29453333 DOI: 10.1038/s41598-018-21194-3  0.4
2018 Tanaka Y, Sone T, Higurashi N, Sakuma T, Suzuki S, Ishikawa M, Yamamoto T, Mitsui J, Tsuji H, Okano H, Hirose S. Generation of D1-1 TALEN isogenic control cell line from Dravet syndrome patient iPSCs using TALEN-mediated editing of the SCN1A gene. Stem Cell Research. 28: 100-104. PMID 29453127 DOI: 10.1016/j.scr.2018.01.036  0.4
2018 Sakuma T, Mochida K, Nakade S, Ezure T, Minagawa S, Yamamoto T. Unexpected heterogeneity derived from Cas9 ribonucleoprotein-introduced clonal cells at the HPRT1 locus. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. PMID 29423928 DOI: 10.1111/gtc.12569  0.4
2018 Sato'o Y, Hisatsune J, Yu L, Sakuma T, Yamamoto T, Sugai M. Tailor-made gene silencing of Staphylococcus aureus clinical isolates by CRISPR interference. Plos One. 13: e0185987. PMID 29377933 DOI: 10.1371/journal.pone.0185987  0.4
2018 Sakuma T, Yamamoto T. Genome editing for dissecting and curing human genetic diseases. Journal of Human Genetics. 63: 105. PMID 29367726 DOI: 10.1038/s10038-017-0380-0  0.4
2017 Kawabe Y, Komatsu S, Komatsu S, Murakami M, Ito A, Sakuma T, Nakamura T, Yamamoto T, Kamihira M. Targeted knock-in of an scFv-Fc antibody gene into the hprt locus of Chinese hamster ovary cells using CRISPR/Cas9 and CRIS-PITCh systems. Journal of Bioscience and Bioengineering. PMID 29295784 DOI: 10.1016/j.jbiosc.2017.12.003  0.4
2017 Nakade S, Yamamoto T, Sakuma T. Cancer induction and suppression with transcriptional control and epigenome editing technologies. Journal of Human Genetics. PMID 29215091 DOI: 10.1038/s10038-017-0377-8  0.4
2017 Tsuda M, Cho K, Ooka M, Shimizu N, Watanabe R, Yasui A, Nakazawa Y, Ogi T, Harada H, Agama K, Nakamura J, Asada R, Fujiike H, Sakuma T, Yamamoto T, et al. ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair. Plos One. 12: e0188320. PMID 29149203 DOI: 10.1371/journal.pone.0188320  0.4
2017 Abe S, Kobayashi K, Oji A, Sakuma T, Kazuki K, Takehara S, Nakamura K, Okada A, Tsukazaki Y, Senda N, Honma K, Yamamoto T, Ikawa M, Chiba K, Oshimura M, et al. Modification of single-nucleotide polymorphism in a fully humanized CYP3A mouse by genome editing technology. Scientific Reports. 7: 15189. PMID 29123154 DOI: 10.1038/s41598-017-15033-0  0.4
2017 Matsuzaki Y, Sakuma T, Yamamoto T, Saya H. Establishment of pten knockout medaka with transcription activator-like effector nucleases (TALENs) as a model of PTEN deficiency disease. Plos One. 12: e0186878. PMID 29053747 DOI: 10.1371/journal.pone.0186878  0.4
2017 Nakamura M, Kumrungsee T, Sakuma T, Yamamoto T, Yanaka N. TALEN-mediated targeted editing of the GDE5 gene suppresses fibroblastic cell proliferation. Bioscience, Biotechnology, and Biochemistry. 1-4. PMID 28934905 DOI: 10.1080/09168451.2017.1373593  0.4
2017 Sakuma T, Yamamoto T. Magic wands of CRISPR-lots of choices for gene knock-in. Cell Biology and Toxicology. PMID 28828704 DOI: 10.1007/s10565-017-9409-6  0.4
2017 Takata N, Sakakura E, Sakuma T, Yamamoto T. Genetic Tools for Self-Organizing Culture of Mouse Embryonic Stem Cells via Small Regulatory RNA-Mediated Technologies, CRISPR/Cas9, and Inducible RNAi. Methods in Molecular Biology (Clifton, N.J.). 1622: 269-292. PMID 28674815 DOI: 10.1007/978-1-4939-7108-4_19  0.4
2017 Kaku Y, Taguchi A, Tanigawa S, Haque F, Sakuma T, Yamamoto T, Nishinakamura R. PAX2 is dispensable for in vitro nephron formation from human induced pluripotent stem cells. Scientific Reports. 7: 4554. PMID 28674456 DOI: 10.1038/s41598-017-04813-3  0.4
2017 Sakuma T, Yamamoto T. Current Overview of TALEN Construction Systems. Methods in Molecular Biology (Clifton, N.J.). 1630: 25-36. PMID 28643246 DOI: 10.1007/978-1-4939-7128-2_2  0.4
2017 Nakamae K, Nishimura Y, Takenaga M, Nakade S, Sakamoto N, Ide H, Sakuma T, Yamamoto T. Establishment of expanded and streamlined pipeline of PITCh knock-in - a web-based design tool for MMEJ-mediated gene knock-in, PITCh designer, and the variations of PITCh, PITCh-TG and PITCh-KIKO. Bioengineered. 1-7. PMID 28453368 DOI: 10.1080/21655979.2017.1313645  0.4
2017 Nakagawa Y, Sakuma T, Nishimichi N, Yokosaki Y, Takeo T, Nakagata N, Yamamoto T. Culture time of vitrified/warmed zygotes before microinjection affects the production efficiency of CRISPR-Cas9-mediated knock-in mice. Biology Open. PMID 28396487 DOI: 10.1242/bio.025122  0.4
2017 Takayama K, Igai K, Hagihara Y, Hashimoto R, Hanawa M, Sakuma T, Tachibana M, Sakurai F, Yamamoto T, Mizuguchi H. Highly efficient biallelic genome editing of human ES/iPS cells using a CRISPR/Cas9 or TALEN system. Nucleic Acids Research. PMID 28334759 DOI: 10.1093/nar/gkx130  0.4
2017 Yoshida K, Nakahata A, Treen N, Sakuma T, Yamamoto T, Sasakura Y. Hox-mediated endodermal identity patterns the pharyngeal muscle formation in the chordate pharynx. Development (Cambridge, England). PMID 28289133 DOI: 10.1242/dev.144436  0.4
2017 Yoshida K, Hozumi A, Treen N, Sakuma T, Yamamoto T, Shirae-Kurabayashi M, Sasakura Y. Germ cell regeneration-mediated, enhanced mutagenesis in the ascidian Ciona intestinalis reveals flexible germ cell formation from different somatic cells. Developmental Biology. PMID 28161521 DOI: 10.1016/j.ydbio.2017.01.022  0.4
2017 Nakade S, Yamamoto T, Sakuma T. Cas9, Cpf1 and C2c1/2/3-What's next? Bioengineered. 0. PMID 28140746 DOI: 10.1080/21655979.2017.1282018  0.4
2017 Sakuma T, Sakamoto T, Yamamoto T. All-in-One CRISPR-Cas9/FokI-dCas9 Vector-Mediated Multiplex Genome Engineering in Cultured Cells. Methods in Molecular Biology (Clifton, N.J.). 1498: 41-56. PMID 27709568 DOI: 10.1007/978-1-4939-6472-7_4  0.4
2016 Sasakura Y, Ogura Y, Treen N, Yokomori R, Park SJ, Nakai K, Saiga H, Sakuma T, Yamamoto T, Fujiwara S, Yoshida K. Transcriptional regulation of a horizontally transferred gene from bacterium to chordate. Proceedings. Biological Sciences. 283. PMID 28003446 DOI: 10.1098/rspb.2016.1712  0.4
2016 Aida T, Nakade S, Sakuma T, Izu Y, Oishi A, Mochida K, Ishikubo H, Usami T, Aizawa H, Yamamoto T, Tanaka K. Gene cassette knock-in in mammalian cells and zygotes by enhanced MMEJ. Bmc Genomics. 17: 979. PMID 27894274 DOI: 10.1186/s12864-016-3331-9  0.4
2016 Toyonaga K, Torigoe S, Motomura Y, Kamichi T, Hayashi JM, Morita YS, Noguchi N, Chuma Y, Kiyohara H, Matsuo K, Tanaka H, Nakagawa Y, Sakuma T, Ohmuraya M, Yamamoto T, et al. C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection. Immunity. PMID 27887882 DOI: 10.1016/j.immuni.2016.10.012  0.4
2016 Tochio N, Umehara K, Uewaki JI, Flechsig H, Kondo M, Dewa T, Sakuma T, Yamamoto T, Saitoh T, Togashi Y, Tate SI. Non-RVD mutations that enhance the dynamics of the TAL repeat array along the superhelical axis improve TALEN genome editing efficacy. Scientific Reports. 6: 37887. PMID 27883072 DOI: 10.1038/srep37887  0.4
2016 Mizutani O, Arazoe T, Toshida K, Hayashi R, Ohsato S, Sakuma T, Yamamoto T, Kuwata S, Yamada O. Detailed analysis of targeted gene mutations caused by the Platinum-Fungal TALENs in Aspergillus oryzae RIB40 strain and a ligD disruptant. Journal of Bioscience and Bioengineering. PMID 27780671 DOI: 10.1016/j.jbiosc.2016.09.014  0.4
2016 Sakuma T, Masaki K, Abe-Chayama H, Mochida K, Yamamoto T, Chayama K. Highly multiplexed CRISPR-Cas9-nuclease and Cas9-nickase vectors for inactivation of hepatitis B virus. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. PMID 27659023 DOI: 10.1111/gtc.12437  0.4
2016 Nakagawa Y, Sakuma T, Nishimichi N, Yokosaki Y, Yanaka N, Takeo T, Nakagata N, Yamamoto T. Ultra-superovulation for the CRISPR-Cas9-mediated production of gene-knockout, single-amino-acid-substituted, and floxed mice. Biology Open. PMID 27387532 DOI: 10.1242/bio.019349  0.4
2016 Sato K, Oiwa R, Kumita W, Henry R, Sakuma T, Ito R, Nozu R, Inoue T, Katano I, Sato K, Okahara N, Okahara J, Shimizu Y, Yamamoto M, Hanazawa K, ... ... Yamamoto T, et al. Generation of a Nonhuman Primate Model of Severe Combined Immunodeficiency Using Highly Efficient Genome Editing. Cell Stem Cell. PMID 27374787 DOI: 10.1016/j.stem.2016.06.003  0.4
2016 Sasaki T, Hanisch FG, Deutzmann R, Sakai LY, Sakuma T, Miyamoto T, Yamamoto T, Hannappel E, Chu ML, Lanig H, von der Mark K. Functional consequence of fibulin-4 missense mutations associated with vascular and skeletal abnormalities and cutis laxa. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 27339457 DOI: 10.1016/j.matbio.2016.06.003  0.4
2016 Nii T, Kohara H, Marumoto T, Sakuma T, Yamamoto T, Tani K. Single-Cell-State Culture of Human Pluripotent Stem Cells Increases Transfection Efficiency. Bioresearch Open Access. 5: 127-36. PMID 27257519 DOI: 10.1089/biores.2016.0009  0.4
2016 Banno K, Omori S, Hirata K, Nawa N, Nakagawa N, Nishimura K, Ohtaka M, Nakanishi M, Sakuma T, Yamamoto T, Toki T, Ito E, Yamamoto T, Kokubu C, Takeda J, et al. Systematic Cellular Disease Models Reveal Synergistic Interaction of Trisomy 21 and GATA1 Mutations in Hematopoietic Abnormalities. Cell Reports. PMID 27134169 DOI: 10.1016/j.celrep.2016.04.031  0.4
2016 Nakahara Y, Muto A, Hirabayashi R, Sakuma T, Yamamoto T, Kume S, Kikuchi Y. Temporal effects of Notch signaling and potential cooperation with multiple downstream effectors on adenohypophysis cell specification in zebrafish. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. PMID 27027936 DOI: 10.1111/gtc.12358  0.4
2016 Nishitani A, Tanaka M, Shimizu S, Kunisawa N, Yokoe M, Yoshida Y, Suzuki T, Sakuma T, Yamamoto T, Kuwamura M, Takenaka S, Ohono Y, Kuramoto T. Involvement of aspartoacylase in tremor expression in rats. Experimental Animals / Japanese Association For Laboratory Animal Science. PMID 27026062 DOI: 10.1538/expanim.16-0007  0.4
2016 Ichiyanagi N, Fujimori K, Yano M, Ishihara-Fujisaki C, Sone T, Akiyama T, Okada Y, Akamatsu W, Matsumoto T, Ishikawa M, Nishimoto Y, Ishihara Y, Sakuma T, Yamamoto T, Tsuiji H, et al. Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells. Stem Cell Reports. PMID 26997647 DOI: 10.1016/j.stemcr.2016.02.011  0.4
2016 Suzuki M, Takagi C, Miura S, Sakane Y, Suzuki M, Sakuma T, Sakamoto N, Endo T, Kamei Y, Sato Y, Kimura H, Yamamoto T, Ueno N, Suzuki KT. In vivo tracking of histone H3 lysine 9 acetylation in Xenopus laevis during tail regeneration. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. PMID 26914410 DOI: 10.1111/gtc.12349  0.4
2016 Marsan E, Ishida S, Schramm A, Weckhuysen S, Muraca G, Lecas S, Liang N, Treins C, Pende M, Roussel D, Le Van Quyen M, Mashimo T, Kaneko T, Yamamoto T, Sakuma T, et al. Depdc5 knockout rat: A novel model of mTORopathy. Neurobiology of Disease. 89: 180-189. PMID 26873552 DOI: 10.1016/j.nbd.2016.02.010  0.4
2016 Takata N, Sakakura E, Kasukawa T, Sakuma T, Yamamoto T, Sasai Y. Establishment of functional genomics pipeline in epiblast-like tissue by combining transcriptomic analysis and gene knock-down/-in/-out using RNAi and CRISPR/Cas9. Human Gene Therapy. PMID 26839115 DOI: 10.1089/hum.2015.148  0.4
2016 Guo L, Yamashita H, Kou I, Takimoto A, Meguro-Horike M, Horike S, Sakuma T, Miura S, Adachi T, Yamamoto T, Ikegawa S, Hiraki Y, Shukunami C. Functional Investigation of a Non-coding Variant Associated with Adolescent Idiopathic Scoliosis in Zebrafish: Elevated Expression of the Ladybird Homeobox Gene Causes Body Axis Deformation. Plos Genetics. 12: e1005802. PMID 26820155 DOI: 10.1371/journal.pgen.1005802  0.4
2016 Sakuma T, Nakade S, Sakane Y, Suzuki KT, Yamamoto T. MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems. Nature Protocols. 11: 118-33. PMID 26678082 DOI: 10.1038/nprot.2015.140  0.4
2016 Sakuma T, Yamamoto T. Engineering Customized TALENs Using the Platinum Gate TALEN Kit. Methods in Molecular Biology (Clifton, N.J.). 1338: 61-70. PMID 26443214 DOI: 10.1007/978-1-4939-2932-0_6  0.4
2015 Sharmin S, Taguchi A, Kaku Y, Yoshimura Y, Ohmori T, Sakuma T, Mukoyama M, Yamamoto T, Kurihara H, Nishinakamura R. Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation. Journal of the American Society of Nephrology : Jasn. PMID 26586691 DOI: 10.1681/ASN.2015010096  0.4
2015 Miyamoto K, Suzuki KT, Suzuki M, Sakane Y, Sakuma T, Herberg S, Simeone A, Simpson D, Jullien J, Yamamoto T, Gurdon JB. The Expression of TALEN before Fertilization Provides a Rapid Knock-Out Phenotype in Xenopus laevis Founder Embryos. Plos One. 10: e0142946. PMID 26580070 DOI: 10.1371/journal.pone.0142946  0.4
2015 Hoa NN, Akagawa R, Yamasaki T, Hirota K, Sasa K, Natsume T, Kobayashi J, Sakuma T, Yamamoto T, Komatsu K, Kanemaki MT, Pommier Y, Takeda S, Sasanuma H. Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell lines. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. PMID 26525166 DOI: 10.1111/gtc.12310  0.4
2015 Rao S, Fujimura T, Matsunari H, Sakuma T, Nakano K, Watanabe M, Asano Y, Kitagawa E, Yamamoto T, Nagashima H. Efficient modification of the myostatin gene in porcine somatic cells and generation of knockout piglets. Molecular Reproduction and Development. PMID 26488621 DOI: 10.1002/mrd.22591  0.4
2015 Sakuma T, Takenaga M, Kawabe Y, Nakamura T, Kamihira M, Yamamoto T. Homologous Recombination-Independent Large Gene Cassette Knock-in in CHO Cells Using TALEN and MMEJ-Directed Donor Plasmids. International Journal of Molecular Sciences. 16: 23849-66. PMID 26473830 DOI: 10.3390/ijms161023849  0.4
2015 Fujiwara M, Fujimura K, Obata S, Yanagibashi R, Sakuma T, Yamamoto T, T Suzuki S. Epithelial DLD-1 Cells with Disrupted E-cadherin Gene Retain the Ability to Form Cell Junctions and Apico-basal Polarity. Cell Structure and Function. 40: 79-94. PMID 26289297 DOI: 10.1247/csf.15002  0.4
2015 Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, ... ... Yamamoto T, et al. Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. Cell Stem Cell. 17: 178-94. PMID 26189426 DOI: 10.1016/j.stem.2015.06.014  0.4
2015 Sato T, Sakuma T, Yokonishi T, Katagiri K, Kamimura S, Ogonuki N, Ogura A, Yamamoto T, Ogawa T. Genome Editing in Mouse Spermatogonial Stem Cell Lines Using TALEN and Double-Nicking CRISPR/Cas9. Stem Cell Reports. 5: 75-82. PMID 26095606 DOI: 10.1016/j.stemcr.2015.05.011  0.4
2015 Keka IS, Mohiuddin, Maede Y, Rahman MM, Sakuma T, Honma M, Yamamoto T, Takeda S, Sasanuma H. Smarcal1 promotes double-strand-break repair by nonhomologous end-joining. Nucleic Acids Research. 43: 6359-72. PMID 26089390 DOI: 10.1093/nar/gkv621  0.4
2015 Hara S, Tamano M, Yamashita S, Kato T, Saito T, Sakuma T, Yamamoto T, Inui M, Takada S. Generation of mutant mice via the CRISPR/Cas9 system using FokI-dCas9. Scientific Reports. 5: 11221. PMID 26057433 DOI: 10.1038/srep11221  0.4
2015 Nakagawa Y, Sakuma T, Sakamoto T, Ohmuraya M, Nakagata N, Yamamoto T. Production of knockout mice by DNA microinjection of various CRISPR/Cas9 vectors into freeze-thawed fertilized oocytes. Bmc Biotechnology. 15: 33. PMID 25997509 DOI: 10.1186/s12896-015-0144-x  0.4
2015 Fujiwara M, Nagatomo A, Tsuda M, Obata S, Sakuma T, Yamamoto T, Suzuki ST. Desmocollin-2 alone forms functional desmosomal plaques, with the plaque formation requiring the juxtamembrane region and plakophilins. Journal of Biochemistry. 158: 339-53. PMID 25972099 DOI: 10.1093/jb/mvv048  0.4
2015 Aida T, Chiyo K, Usami T, Ishikubo H, Imahashi R, Wada Y, Tanaka KF, Sakuma T, Yamamoto T, Tanaka K. Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice. Genome Biology. 16: 87. PMID 25924609 DOI: 10.1186/s13059-015-0653-x  0.4
2015 Nakade S, Sakuma T, Sakane Y, Hara Y, Kurabayashi A, Kashiwagi K, Kashiwagi A, Yamamoto T, Obara M. Homeolog-specific targeted mutagenesis in Xenopus laevis using TALENs. In Vitro Cellular & Developmental Biology. Animal. 51: 879-84. PMID 25920501 DOI: 10.1007/s11626-015-9912-0  0.4
2015 Kawai N, Ogura Y, Ikuta T, Saiga H, Hamada M, Sakuma T, Yamamoto T, Satoh N, Sasakura Y. Hox10-regulated endodermal cell migration is essential for development of the ascidian intestine. Developmental Biology. 403: 43-56. PMID 25888074 DOI: 10.1016/j.ydbio.2015.03.018  0.4
2015 Ebina H, Kanemura Y, Misawa N, Sakuma T, Kobayashi T, Yamamoto T, Koyanagi Y. A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector. Plos One. 10: e0120047. PMID 25781496 DOI: 10.1371/journal.pone.0120047  0.4
2015 Hisano Y, Sakuma T, Nakade S, Ohga R, Ota S, Okamoto H, Yamamoto T, Kawahara A. Precise in-frame integration of exogenous DNA mediated by CRISPR/Cas9 system in zebrafish. Scientific Reports. 5: 8841. PMID 25740433 DOI: 10.1038/srep08841  0.4
2015 Arazoe T, Ogawa T, Miyoshi K, Yamato T, Ohsato S, Sakuma T, Yamamoto T, Arie T, Kuwata S. Tailor-made TALEN system for highly efficient targeted gene replacement in the rice blast fungus. Biotechnology and Bioengineering. 112: 1335-42. PMID 25683503 DOI: 10.1002/bit.25559  0.4
2015 Miyamoto T, Hosoba K, Ochiai H, Royba E, Izumi H, Sakuma T, Yamamoto T, Dynlacht BD, Matsuura S. The Microtubule-Depolymerizing Activity of a Mitotic Kinesin Protein KIF2A Drives Primary Cilia Disassembly Coupled with Cell Proliferation. Cell Reports. PMID 25660017 DOI: 10.1016/j.celrep.2015.01.003  0.4
2015 Choi J, Suzuki KT, Sakuma T, Shewade L, Yamamoto T, Buchholz DR. Unliganded thyroid hormone receptor α regulates developmental timing via gene repression in Xenopus tropicalis. Endocrinology. 156: 735-44. PMID 25456067 DOI: 10.1210/en.2014-1554  0.4
2015 Li HL, Fujimoto N, Sasakawa N, Shirai S, Ohkame T, Sakuma T, Tanaka M, Amano N, Watanabe A, Sakurai H, Yamamoto T, Yamanaka S, Hotta A. Precise correction of the dystrophin gene in duchenne muscular dystrophy patient induced pluripotent stem cells by TALEN and CRISPR-Cas9. Stem Cell Reports. 4: 143-54. PMID 25434822 DOI: 10.1016/j.stemcr.2014.10.013  0.4
2014 Yamamoto T, Sakamoto N, Sakuma T. [Genome editing with programmable site-specific nucleases]. Uirusu. 64: 75-82. PMID 25765983 DOI: 10.2222/jsv.64.75  0.4
2014 Nakade S, Tsubota T, Sakane Y, Kume S, Sakamoto N, Obara M, Daimon T, Sezutsu H, Yamamoto T, Sakuma T, Suzuki KT. Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9. Nature Communications. 5: 5560. PMID 25410609 DOI: 10.1038/ncomms6560  0.4
2014 Ochiai H, Sugawara T, Sakuma T, Yamamoto T. Stochastic promoter activation affects Nanog expression variability in mouse embryonic stem cells. Scientific Reports. 4: 7125. PMID 25410303 DOI: 10.1038/srep07125  0.4
2014 Hiruta C, Ogino Y, Sakuma T, Toyota K, Miyagawa S, Yamamoto T, Iguchi T. Targeted gene disruption by use of transcription activator-like effector nuclease (TALEN) in the water flea Daphnia pulex. Bmc Biotechnology. 14: 95. PMID 25404042 DOI: 10.1186/s12896-014-0095-7  0.4
2014 Kaneko T, Sakuma T, Yamamoto T, Mashimo T. Simple knockout by electroporation of engineered endonucleases into intact rat embryos. Scientific Reports. 4: 6382. PMID 25269785 DOI: 10.1038/srep06382  0.4
2014 Sawai S, Ohyama K, Yasumoto S, Seki H, Sakuma T, Yamamoto T, Takebayashi Y, Kojima M, Sakakibara H, Aoki T, Muranaka T, Saito K, Umemoto N. Sterol side chain reductase 2 is a key enzyme in the biosynthesis of cholesterol, the common precursor of toxic steroidal glycoalkaloids in potato. The Plant Cell. 26: 3763-74. PMID 25217510 DOI: 10.1105/tpc.114.130096  0.4
2014 Kazuki Y, Yakura Y, Abe S, Osaki M, Kajitani N, Kazuki K, Takehara S, Honma K, Suemori H, Yamazaki S, Sakuma T, Toki T, Shimizu R, Nakauchi H, Yamamoto T, et al. Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies. Scientific Reports. 4: 6136. PMID 25159877 DOI: 10.1038/srep06136  0.4
2014 Ninagawa S, Okada T, Sumitomo Y, Kamiya Y, Kato K, Horimoto S, Ishikawa T, Takeda S, Sakuma T, Yamamoto T, Mori K. EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step. The Journal of Cell Biology. 206: 347-56. PMID 25092655 DOI: 10.1083/jcb.201404075  0.4
2014 Nakagawa Y, Sakuma T, Nakagata N, Yamasaki S, Takeda N, Ohmuraya M, Yamamoto T. Application of oocyte cryopreservation technology in TALEN-mediated mouse genome editing. Experimental Animals / Japanese Association For Laboratory Animal Science. 63: 349-55. PMID 25077765 DOI: DN/JST.JSTAGE/expanim/14-0013  0.4
2014 Yasue A, Mitsui SN, Watanabe T, Sakuma T, Oyadomari S, Yamamoto T, Noji S, Mito T, Tanaka E. Highly efficient targeted mutagenesis in one-cell mouse embryos mediated by the TALEN and CRISPR/Cas systems. Scientific Reports. 4: 5705. PMID 25027812 DOI: 10.1038/srep05705  0.4
2014 Sakuma T, Nishikawa A, Kume S, Chayama K, Yamamoto T. Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system. Scientific Reports. 4: 5400. PMID 24954249 DOI: 10.1038/srep05400  0.4
2014 Tokumasu D, Sakuma T, Hayashi Y, Hosoi S, Hiyama E, Yamamoto T. FAST-id system for enrichment of cells with TALEN-induced mutations and large deletions. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 19: 419-31. PMID 24636012 DOI: 10.1111/gtc.12142  0.4
2014 Yoshida K, Treen N, Hozumi A, Sakuma T, Yamamoto T, Sasakura Y. Germ cell mutations of the ascidian Ciona intestinalis with TALE nucleases. Genesis (New York, N.Y. : 2000). 52: 431-9. PMID 24619765 DOI: 10.1002/dvg.22770  0.4
2014 Nakagawa Y, Yamamoto T, Suzuki KI, Araki K, Takeda N, Ohmuraya M, Sakuma T. Screening methods to identify TALEN-mediated knockout mice Experimental Animals. 63: 79-84. PMID 24521866 DOI: 10.1538/expanim.63.79  0.4
2014 Sugi T, Sakuma T, Ohtani Y, Yamamoto T. Versatile strategy for isolating transcription activator-like effector nuclease-mediated knockout mutants in Caenorhabditis elegans. Development, Growth & Differentiation. 56: 78-85. PMID 24409999 DOI: 10.1111/dgd.12108  0.4
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