Hector Serrano, Ph.D. - Publications

Affiliations: 
2009 Pharmacy University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Biochemistry

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Poelarends GJ, Serrano H, Huddleston JP, Johnson WH, Whitman CP. A mutational analysis of active site residues in trans-3-chloroacrylic acid dehalogenase. Febs Letters. 587: 2842-50. PMID 23851010 DOI: 10.1016/J.Febslet.2013.07.006  0.731
2013 Guo Y, Serrano H, Poelarends GJ, Johnson WH, Hackert ML, Whitman CP. Kinetic, mutational, and structural analysis of malonate semialdehyde decarboxylase from Coryneform bacterium strain FG41: mechanistic implications for the decarboxylase and hydratase activities. Biochemistry. 52: 4830-41. PMID 23781927 DOI: 10.1021/Bi400567A  0.74
2012 Schroeder GK, Johnson WH, Huddleston JP, Serrano H, Johnson KA, Whitman CP. Reaction of cis-3-chloroacrylic acid dehalogenase with an allene substrate, 2,3-butadienoate: hydration via an enamine. Journal of the American Chemical Society. 134: 293-304. PMID 22129074 DOI: 10.1021/Ja206873F  0.693
2011 Guo Y, Serrano H, Johnson WH, Ernst S, Hackert ML, Whitman CP. Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase: Implications for the catalytic and inactivation mechanisms. Bioorganic Chemistry. 39: 1-9. PMID 21074239 DOI: 10.1016/J.Bioorg.2010.10.001  0.752
2008 Pegan SD, Serrano H, Whitman CP, Mesecar AD. Structural and mechanistic analysis of trans-3-chloroacrylic acid dehalogenase activity. Acta Crystallographica. Section D, Biological Crystallography. 64: 1277-82. PMID 19018104 DOI: 10.1107/S0907444908034707  0.717
2008 Poelarends GJ, Serrano H, Person MD, Johnson WH, Whitman CP. Characterization of Cg10062 from Corynebacterium glutamicum: implications for the evolution of cis-3-chloroacrylic acid dehalogenase activity in the tautomerase superfamily. Biochemistry. 47: 8139-47. PMID 18598055 DOI: 10.1021/Bi8007388  0.731
2007 Poelarends GJ, Johnson WH, Serrano H, Whitman CP. Phenylpyruvate tautomerase activity of trans-3-chloroacrylic acid dehalogenase: evidence for an enol intermediate in the dehalogenase reaction? Biochemistry. 46: 9596-604. PMID 17661448 DOI: 10.1021/Bi7007189  0.729
2007 de Jong RM, Bazzacco P, Poelarends GJ, Johnson WH, Kim YJ, Burks EA, Serrano H, Thunnissen AM, Whitman CP, Dijkstra BW. Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase. Structural basis for substrate specificity and inactivation by (R)-oxirane-2-carboxylate. The Journal of Biological Chemistry. 282: 2440-9. PMID 17121835 DOI: 10.1074/Jbc.M608134200  0.725
2006 Poelarends GJ, Almrud JJ, Serrano H, Darty JE, Johnson WH, Hackert ML, Whitman CP. Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural consequences of the L8R mutation in 4-oxalocrotonate tautomerase. Biochemistry. 45: 7700-8. PMID 16784221 DOI: 10.1021/Bi0600603  0.599
2005 Almrud JJ, Poelarends GJ, Johnson WH, Serrano H, Hackert ML, Whitman CP. Crystal structures of the wild-type, P1A mutant, and inactivated malonate semialdehyde decarboxylase: a structural basis for the decarboxylase and hydratase activities. Biochemistry. 44: 14818-27. PMID 16274229 DOI: 10.1021/Bi051383M  0.715
2005 Poelarends GJ, Serrano H, Johnson WH, Whitman CP. Inactivation of malonate semialdehyde decarboxylase by 3-halopropiolates: evidence for hydratase activity. Biochemistry. 44: 9375-81. PMID 15982004 DOI: 10.1021/Bi050296R  0.755
2004 Poelarends GJ, Serrano H, Johnson WH, Hoffman DW, Whitman CP. The hydratase activity of malonate semialdehyde decarboxylase: mechanistic and evolutionary implications. Journal of the American Chemical Society. 126: 15658-9. PMID 15571384 DOI: 10.1021/Ja044304N  0.726
2004 Poelarends GJ, Serrano H, Johnson WH, Whitman CP. Stereospecific alkylation of cis-3-chloroacrylic acid dehalogenase by (R)-oxirane-2-carboxylate: analysis and mechanistic implications. Biochemistry. 43: 7187-96. PMID 15170356 DOI: 10.1021/Bi049823H  0.734
2004 Poelarends GJ, Serrano H, Person MD, Johnson WH, Murzin AG, Whitman CP. Cloning, expression, and characterization of a cis-3-chloroacrylic acid dehalogenase: insights into the mechanistic, structural, and evolutionary relationship between isomer-specific 3-chloroacrylic acid dehalogenases. Biochemistry. 43: 759-72. PMID 14730981 DOI: 10.1021/Bi0355948  0.715
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