Year |
Citation |
Score |
2013 |
Poelarends GJ, Serrano H, Huddleston JP, Johnson WH, Whitman CP. A mutational analysis of active site residues in trans-3-chloroacrylic acid dehalogenase. Febs Letters. 587: 2842-50. PMID 23851010 DOI: 10.1016/J.Febslet.2013.07.006 |
0.731 |
|
2013 |
Guo Y, Serrano H, Poelarends GJ, Johnson WH, Hackert ML, Whitman CP. Kinetic, mutational, and structural analysis of malonate semialdehyde decarboxylase from Coryneform bacterium strain FG41: mechanistic implications for the decarboxylase and hydratase activities. Biochemistry. 52: 4830-41. PMID 23781927 DOI: 10.1021/Bi400567A |
0.74 |
|
2012 |
Schroeder GK, Johnson WH, Huddleston JP, Serrano H, Johnson KA, Whitman CP. Reaction of cis-3-chloroacrylic acid dehalogenase with an allene substrate, 2,3-butadienoate: hydration via an enamine. Journal of the American Chemical Society. 134: 293-304. PMID 22129074 DOI: 10.1021/Ja206873F |
0.693 |
|
2011 |
Guo Y, Serrano H, Johnson WH, Ernst S, Hackert ML, Whitman CP. Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase: Implications for the catalytic and inactivation mechanisms. Bioorganic Chemistry. 39: 1-9. PMID 21074239 DOI: 10.1016/J.Bioorg.2010.10.001 |
0.752 |
|
2008 |
Pegan SD, Serrano H, Whitman CP, Mesecar AD. Structural and mechanistic analysis of trans-3-chloroacrylic acid dehalogenase activity. Acta Crystallographica. Section D, Biological Crystallography. 64: 1277-82. PMID 19018104 DOI: 10.1107/S0907444908034707 |
0.717 |
|
2008 |
Poelarends GJ, Serrano H, Person MD, Johnson WH, Whitman CP. Characterization of Cg10062 from Corynebacterium glutamicum: implications for the evolution of cis-3-chloroacrylic acid dehalogenase activity in the tautomerase superfamily. Biochemistry. 47: 8139-47. PMID 18598055 DOI: 10.1021/Bi8007388 |
0.731 |
|
2007 |
Poelarends GJ, Johnson WH, Serrano H, Whitman CP. Phenylpyruvate tautomerase activity of trans-3-chloroacrylic acid dehalogenase: evidence for an enol intermediate in the dehalogenase reaction? Biochemistry. 46: 9596-604. PMID 17661448 DOI: 10.1021/Bi7007189 |
0.729 |
|
2007 |
de Jong RM, Bazzacco P, Poelarends GJ, Johnson WH, Kim YJ, Burks EA, Serrano H, Thunnissen AM, Whitman CP, Dijkstra BW. Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase. Structural basis for substrate specificity and inactivation by (R)-oxirane-2-carboxylate. The Journal of Biological Chemistry. 282: 2440-9. PMID 17121835 DOI: 10.1074/Jbc.M608134200 |
0.725 |
|
2006 |
Poelarends GJ, Almrud JJ, Serrano H, Darty JE, Johnson WH, Hackert ML, Whitman CP. Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural consequences of the L8R mutation in 4-oxalocrotonate tautomerase. Biochemistry. 45: 7700-8. PMID 16784221 DOI: 10.1021/Bi0600603 |
0.599 |
|
2005 |
Almrud JJ, Poelarends GJ, Johnson WH, Serrano H, Hackert ML, Whitman CP. Crystal structures of the wild-type, P1A mutant, and inactivated malonate semialdehyde decarboxylase: a structural basis for the decarboxylase and hydratase activities. Biochemistry. 44: 14818-27. PMID 16274229 DOI: 10.1021/Bi051383M |
0.715 |
|
2005 |
Poelarends GJ, Serrano H, Johnson WH, Whitman CP. Inactivation of malonate semialdehyde decarboxylase by 3-halopropiolates: evidence for hydratase activity. Biochemistry. 44: 9375-81. PMID 15982004 DOI: 10.1021/Bi050296R |
0.755 |
|
2004 |
Poelarends GJ, Serrano H, Johnson WH, Hoffman DW, Whitman CP. The hydratase activity of malonate semialdehyde decarboxylase: mechanistic and evolutionary implications. Journal of the American Chemical Society. 126: 15658-9. PMID 15571384 DOI: 10.1021/Ja044304N |
0.726 |
|
2004 |
Poelarends GJ, Serrano H, Johnson WH, Whitman CP. Stereospecific alkylation of cis-3-chloroacrylic acid dehalogenase by (R)-oxirane-2-carboxylate: analysis and mechanistic implications. Biochemistry. 43: 7187-96. PMID 15170356 DOI: 10.1021/Bi049823H |
0.734 |
|
2004 |
Poelarends GJ, Serrano H, Person MD, Johnson WH, Murzin AG, Whitman CP. Cloning, expression, and characterization of a cis-3-chloroacrylic acid dehalogenase: insights into the mechanistic, structural, and evolutionary relationship between isomer-specific 3-chloroacrylic acid dehalogenases. Biochemistry. 43: 759-72. PMID 14730981 DOI: 10.1021/Bi0355948 |
0.715 |
|
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