Charles Nicholson - Publications

Affiliations: 
New York University School of Medicine, New York, NY, United States 
Area:
Extracellular diffusion
Website:
http://www.med.nyu.edu/research/nichoc01.html

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Nicholson C. Sheet and void porous media models for brain interstitial space. Journal of the Royal Society, Interface. 20: 20230223. PMID 37553990 DOI: 10.1098/rsif.2023.0223  0.301
2022 Bohr T, Hjorth PG, Holst SC, Hrabětová S, Kiviniemi V, Lilius T, Lundgaard I, Mardal KA, Martens EA, Mori Y, Nägerl UV, Nicholson C, Tannenbaum A, Thomas JH, Tithof J, et al. The glymphatic system: Current understanding and modeling. Iscience. 25: 104987. PMID 36093063 DOI: 10.1016/j.isci.2022.104987  0.659
2021 Colbourn R, Hrabe J, Nicholson C, Perkins M, Goodman JH, Hrabetova S. Rapid volume pulsation of the extracellular space coincides with epileptiform activity in mice and depends on the NBCe1 transporter. The Journal of Physiology. PMID 33942325 DOI: 10.1113/JP281544  0.65
2018 Patel JC, Stouffer MA, Mancini M, Nicholson C, Carr KD, Rice ME. Interactions between insulin and diet on striatal dopamine uptake kinetics in rodent brain slices. The European Journal of Neuroscience. PMID 29791756 DOI: 10.1111/Ejn.13958  0.419
2017 Odackal J, Colbourn R, Odackal NJ, Tao L, Nicholson C, Hrabetova S. Real-time Iontophoresis with Tetramethylammonium to Quantify Volume Fraction and Tortuosity of Brain Extracellular Space. Journal of Visualized Experiments : Jove. PMID 28784968 DOI: 10.3791/55755  0.716
2017 Nicholson C, Hrabětová S. Brain Extracellular Space: The Final Frontier of Neuroscience. Biophysical Journal. PMID 28755756 DOI: 10.1016/j.bpj.2017.06.052  0.719
2015 Chodobski A, Ghersi-Egea JF, Nicholson C, Nagaraja TN, Szmydynger-Chodobska J. The quest for a better insight into physiology of fluids and barriers of the brain: the exemplary career of Joseph D. Fenstermacher. Fluids and Barriers of the Cns. 12: 1. PMID 25745556 DOI: 10.1186/2045-8118-12-1  0.356
2013 Kamali-Zare P, Nicholson C. Modeling Calcium Diffusion in Chondroitin Sulfate using a Bimolecular Reaction Scheme Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.919  0.345
2011 Nicholson C, Kamali-Zare P, Tao L. Brain Extracellular Space as a Diffusion Barrier. Computing and Visualization in Science. 14: 309-325. PMID 23172993 DOI: 10.1007/s00791-012-0185-9  0.486
2011 Nicholson C. Diffusion from Point-Source in Oriented Fiber Ensembles with Different Volume Fractions Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.734  0.385
2010 Li X, Patel JC, Wang J, Avshalumov MV, Nicholson C, Buxbaum JD, Elder GA, Rice ME, Yue Z. Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1788-97. PMID 20130188 DOI: 10.1523/Jneurosci.5604-09.2010  0.483
2009 Hrabetová S, Masri D, Tao L, Xiao F, Nicholson C. Calcium diffusion enhanced after cleavage of negatively charged components of brain extracellular matrix by chondroitinase ABC. The Journal of Physiology. 587: 4029-49. PMID 19546165 DOI: 10.1113/jphysiol.2009.170092  0.729
2008 Syková E, Nicholson C. Diffusion in brain extracellular space. Physiological Reviews. 88: 1277-340. PMID 18923183 DOI: 10.1152/physrev.00027.2007  0.468
2008 Thorne RG, Lakkaraju A, Rodriguez-Boulan E, Nicholson C. In vivo diffusion of lactoferrin in brain extracellular space is regulated by interactions with heparan sulfate. Proceedings of the National Academy of Sciences of the United States of America. 105: 8416-21. PMID 18541909 DOI: 10.1073/Pnas.0711345105  0.735
2008 Yao X, Hrabetová S, Nicholson C, Manley GT. Aquaporin-4-deficient mice have increased extracellular space without tortuosity change. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5460-4. PMID 18495879 DOI: 10.1523/Jneurosci.0257-08.2008  0.703
2008 Kaur G, Hrabetova S, Guilfoyle DN, Nicholson C, Hrabe J. Characterizing molecular probes for diffusion measurements in the brain. Journal of Neuroscience Methods. 171: 218-25. PMID 18466980 DOI: 10.1016/j.jneumeth.2008.03.007  0.734
2008 Xiao F, Nicholson C, Hrabe J, Hrabetová S. Diffusion of flexible random-coil dextran polymers measured in anisotropic brain extracellular space by integrative optical imaging. Biophysical Journal. 95: 1382-92. PMID 18456831 DOI: 10.1529/biophysj.107.124743  0.733
2006 Thorne RG, Nicholson C. In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space. Proceedings of the National Academy of Sciences of the United States of America. 103: 5567-72. PMID 16567637 DOI: 10.1073/pnas.0509425103  0.727
2005 Thorne RG, Hrabetová S, Nicholson C. Diffusion measurements for drug design. Nature Materials. 4: 713; author reply 71. PMID 16195756 DOI: 10.1038/Nmat1490  0.755
2005 Tao A, Tao L, Nicholson C. Cell cavities increase tortuosity in brain extracellular space. Journal of Theoretical Biology. 234: 525-36. PMID 15808873 DOI: 10.1016/j.jtbi.2004.12.009  0.363
2005 Nicholson C. Factors governing diffusing molecular signals in brain extracellular space. Journal of Neural Transmission (Vienna, Austria : 1996). 112: 29-44. PMID 15372328 DOI: 10.1007/s00702-004-0204-1  0.366
2004 Thorne RG, Hrabetová S, Nicholson C. Diffusion of epidermal growth factor in rat brain extracellular space measured by integrative optical imaging. Journal of Neurophysiology. 92: 3471-81. PMID 15269225 DOI: 10.1152/jn.00352.2004  0.787
2004 Hrabetová S, Nicholson C. Contribution of dead-space microdomains to tortuosity of brain extracellular space. Neurochemistry International. 45: 467-77. PMID 15186912 DOI: 10.1016/j.neuint.2003.11.011  0.726
2004 Tao L, Nicholson C. Maximum geometrical hindrance to diffusion in brain extracellular space surrounding uniformly spaced convex cells. Journal of Theoretical Biology. 229: 59-68. PMID 15178185 DOI: 10.1016/j.jtbi.2004.03.003  0.363
2003 Hrabetová S, Hrabe J, Nicholson C. Dead-space microdomains hinder extracellular diffusion in rat neocortex during ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8351-9. PMID 12967997  0.735
2002 Chen KC, Nicholson C. Measurement of diffusion parameters using a sinusoidal iontophoretic source in rat cortex. Journal of Neuroscience Methods. 122: 97-108. PMID 12535769 DOI: 10.1016/S0165-0270(02)00299-6  0.407
2002 Tao L, Masri D, Hrabetová S, Nicholson C. Light scattering in rat neocortical slices differs during spreading depression and ischemia. Brain Research. 952: 290-300. PMID 12376191 DOI: 10.1016/S0006-8993(02)03254-7  0.685
2002 Chen KC, Höistad M, Kehr J, Fuxe K, Nicholson C. Quantitative dual-probe microdialysis: mathematical model and analysis. Journal of Neurochemistry. 81: 94-107. PMID 12067242 DOI: 10.1046/j.1471-4159.2002.00792.x  0.46
2002 Höistad M, Chen KC, Nicholson C, Fuxe K, Kehr J. Quantitative dual-probe microdialysis: evaluation of [3H]mannitol diffusion in agar and rat striatum. Journal of Neurochemistry. 81: 80-93. PMID 12067240 DOI: 10.1046/j.1471-4159.2002.00791.x  0.452
2002 Hrabetová S, Chen KC, Masri D, Nicholson C. Water compartmentalization and spread of ischemic injury in thick-slice ischemia model. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 80-8. PMID 11807397 DOI: 10.1097/00004647-200201000-00010  0.676
2001 Cragg SJ, Nicholson C, Kume-Kick J, Tao L, Rice ME. Dopamine-mediated volume transmission in midbrain is regulated by distinct extracellular geometry and uptake. Journal of Neurophysiology. 85: 1761-71. PMID 11287497 DOI: 10.1152/jn.2001.85.4.1761  0.7
2001 Prokopová-Kubinová S, Vargová L, Tao L, Ulbrich K, Subr V, Syková E, Nicholson C. Poly[N-(2-hydroxypropyl)methacrylamide] polymers diffuse in brain extracellular space with same tortuosity as small molecules. Biophysical Journal. 80: 542-8. PMID 11159424 DOI: 10.1016/S0006-3495(01)76036-5  0.405
2001 Nicholson C. Diffusion and related transport mechanisms in brain tissue Reports On Progress in Physics. 64: 815-884. DOI: 10.1088/0034-4885/64/7/202  0.397
2000 Nicholson C, Chen KC, HrabÄ•tová S, Tao L. Diffusion of molecules in brain extracellular space: theory and experiment. Progress in Brain Research. 125: 129-54. PMID 11098654 DOI: 10.1016/S0079-6123(00)25007-3  0.376
2000 Hrabetová S, Nicholson C. Dextran decreases extracellular tortuosity in thick-slice ischemia model. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 1306-10. PMID 10994852 DOI: 10.1097/00004647-200009000-00005  0.707
2000 Chen KC, Nicholson C. Changes in brain cell shape create residual extracellular space volume and explain tortuosity behavior during osmotic challenge. Proceedings of the National Academy of Sciences of the United States of America. 97: 8306-11. PMID 10890922 DOI: 10.1073/pnas.150338197  0.44
2000 Chen KC, Nicholson C. Spatial buffering of potassium ions in brain extracellular space. Biophysical Journal. 78: 2776-97. PMID 10827962 DOI: 10.1016/S0006-3495(00)76822-6  0.351
2000 Martins-Ferreira H, Nedergaard M, Nicholson C. Perspectives on spreading depression. Brain Research. Brain Research Reviews. 32: 215-34. PMID 10751672 DOI: 10.1016/S0165-0173(99)00083-1  0.322
2000 Brahma B, Forman RE, Stewart EE, Nicholson C, Rice ME. Ascorbate inhibits edema in brain slices. Journal of Neurochemistry. 74: 1263-70. PMID 10693960 DOI: 10.1046/J.1471-4159.2000.741263.X  0.527
1999 Nicholson C. Signals that go with the flow. Trends in Neurosciences. 22: 143-5. PMID 10203848 DOI: 10.1016/S0166-2236(98)01388-5  0.328
1998 Nicholson C, Syková E. Extracellular space structure revealed by diffusion analysis. Trends in Neurosciences. 21: 207-15. PMID 9610885 DOI: 10.1016/S0166-2236(98)01261-2  0.392
1997 Schwindt W, Nicholson C, Lehmenkühler A. Critical volume of rat cortex and extracellular threshold concentration for a pentylenetetrazol-induced epileptic focus. Brain Research. 753: 86-97. PMID 9125435 DOI: 10.1016/S0006-8993(96)01495-3  0.358
1996 Tao L, Nicholson C. Diffusion of albumins in rat cortical slices and relevance to volume transmission. Neuroscience. 75: 839-47. PMID 8951877 DOI: 10.1016/0306-4522(96)00303-X  0.459
1996 Krizaj D, Rice ME, Wardle RA, Nicholson C. Water compartmentalization and extracellular tortuosity after osmotic changes in cerebellum of Trachemys scripta. The Journal of Physiology. 492: 887-96. PMID 8734998 DOI: 10.1113/Jphysiol.1996.Sp021354  0.572
1995 Nicholson C. Interaction between diffusion and Michaelis-Menten uptake of dopamine after iontophoresis in striatum. Biophysical Journal. 68: 1699-715. PMID 7612814 DOI: 10.1016/S0006-3495(95)80348-6  0.386
1995 Bjelke B, England R, Nicholson C, Rice ME, Lindberg J, Zoli M, Agnati LF, Fuxe K. Long distance pathways of diffusion for dextran along fibre bundles in brain. Relevance for volume transmission. Neuroreport. 6: 1005-9. PMID 7543300 DOI: 10.1097/00001756-199505090-00014  0.606
1995 Pérez-Pinzón MA, Tao L, Nicholson C. Extracellular potassium, volume fraction, and tortuosity in rat hippocampal CA1, CA3, and cortical slices during ischemia. Journal of Neurophysiology. 74: 565-73. PMID 7472364 DOI: 10.1152/Jn.1995.74.2.565  0.332
1994 Okada YC, Huang JC, Rice ME, Tranchina D, Nicholson C. Origin of the apparent tissue conductivity in the molecular and granular layers of the in vitro turtle cerebellum and the interpretation of current source-density analysis. Journal of Neurophysiology. 72: 742-53. PMID 7983532 DOI: 10.1152/Jn.1994.72.2.742  0.525
1994 Rice ME, Richards CD, Nedergaard S, Hounsgaard J, Nicholson C, Greenfield SA. Direct monitoring of dopamine and 5-HT release in substantia nigra and ventral tegmental area in vitro. Experimental Brain Research. 100: 395-406. PMID 7813678 DOI: 10.1007/BF00229180  0.612
1993 Witkovsky P, Nicholson C, Rice ME, Bohmaker K, Meller E. Extracellular dopamine concentration in the retina of the clawed frog, Xenopus laevis. Proceedings of the National Academy of Sciences of the United States of America. 90: 5667-71. PMID 8516316 DOI: 10.1073/Pnas.90.12.5667  0.463
1993 Nicholson C. Ion-selective microelectrodes and diffusion measurements as tools to explore the brain cell microenvironment. Journal of Neuroscience Methods. 48: 199-213. PMID 8412303 DOI: 10.1016/0165-0270(93)90092-6  0.422
1993 Lehmenkühler A, Syková E, Svoboda J, Zilles K, Nicholson C. Extracellular space parameters in the rat neocortex and subcortical white matter during postnatal development determined by diffusion analysis. Neuroscience. 55: 339-51. PMID 8377929 DOI: 10.1016/0306-4522(93)90503-8  0.373
1993 Köhling R, Lehmenkükhler A, Nicholson C, Speckmann EJ. Superfusion of verapamil on the cerebral cortex does not suppress epileptic discharges due to restricted diffusion (rats, in vivo). Brain Research. 626: 149-55. PMID 8281426 DOI: 10.1016/0006-8993(93)90574-7  0.457
1993 Lücke A, Lehmenkühler A, Altrup U, Nicholson C, Reith H, Schmitz-Moormann C, Speckmann EJ. Diffusion analysis of valproate and trans-2-en-valproate in agar and in cerebral cortex of the rat. Brain Research. 631: 187-90. PMID 8131047 DOI: 10.1016/0006-8993(93)91534-Y  0.384
1993 Nicholson C, Tao L. Hindered diffusion of high molecular weight compounds in brain extracellular microenvironment measured with integrative optical imaging. Biophysical Journal. 65: 2277-90. PMID 7508761 DOI: 10.1016/S0006-3495(93)81324-9  0.43
1993 Rice ME, Okada YC, Nicholson C. Anisotropic and heterogeneous diffusion in the turtle cerebellum: implications for volume transmission. Journal of Neurophysiology. 70: 2035-44. PMID 7507522 DOI: 10.1152/Jn.1993.70.5.2035  0.505
1992 Nicholson C. Quantitative analysis of extracellular space using the method of TMA+ iontophoresis and the issue of TMA+ uptake Canadian Journal of Physiology and Pharmacology. 70. PMID 1295682 DOI: 10.1139/Y92-278  0.34
1991 Lehmenkühler A, Nicholson C, Speckmann EJ. Threshold extracellular concentration distribution of penicillin for generation of epileptic focus measured by diffusion analysis Brain Research. 561: 292-298. PMID 1802346 DOI: 10.1016/0006-8993(91)91607-3  0.369
1990 Huang J, Nicholson C, Okada YC. Distortion of magnetic evoked fields and surface potentials by conductivity differences at boundaries in brain tissue. Biophysical Journal. 57: 1155-1166. PMID 2393701 DOI: 10.1016/S0006-3495(90)82635-7  0.311
1989 Rice ME, Nicholson C. Measurement of nanomolar dopamine diffusion using low-noise perfluorinated ionomer coated carbon fiber microelectrodes and high-speed cyclic voltammetry. Analytical Chemistry. 61: 1805-10. PMID 2802146 DOI: 10.1021/Ac00192A005  0.518
1988 Lehmenkühler A, Kersting U, Nicholson C. Diffusion of penicillin in agar and cerebral cortex of the rat Brain Research. 444: 181-183. PMID 3359288 DOI: 10.1016/0006-8993(88)90926-2  0.358
1988 Rice ME, Nicholson C. Behavior of extracellular K+ and pH in skate (Raja erinacea) cerebellum. Brain Research. 461: 328-34. PMID 3179721 DOI: 10.1016/0006-8993(88)90263-6  0.491
1988 Lauritzen M, Rice ME, Okada Y, Nicholson C. Quisqualate, kainate and NMDA can initiate spreading depression in the turtle cerebellum. Brain Research. 475: 317-27. PMID 2905624 DOI: 10.1016/0006-8993(88)90620-8  0.488
1987 Rice ME, Nicholson C. Interstitial ascorbate in turtle brain is modulated by release and extracellular volume change. Journal of Neurochemistry. 49: 1096-104. PMID 3625202 DOI: 10.1111/J.1471-4159.1987.Tb09999.X  0.555
1987 Nicholson C, Rice ME. Calcium diffusion in the brain cell microenvironment. Canadian Journal of Physiology and Pharmacology. 65: 1086-91. PMID 3621033 DOI: 10.1139/Y87-170  0.575
1986 Nicholson C, Rice ME. The migration of substances in the neuronal microenvironment. Annals of the New York Academy of Sciences. 481: 55-71. PMID 3468865 DOI: 10.1111/J.1749-6632.1986.Tb27139.X  0.469
1986 Rice ME, Nicholson C. Serotonin migration in the neuronal microenvironment Annals of the New York Academy of Sciences. 381-382. DOI: 10.1111/J.1749-6632.1986.Tb27171.X  0.473
1985 Nicholson C. Diffusion from an injected volume of a substance in brain tissue with arbitrary volume fraction and tortuosity Brain Research. 333: 325-329. PMID 3995298 DOI: 10.1016/0006-8993(85)91586-0  0.462
1985 Chesler M, Nicholson C. Regulation of intracellular pH in vertebrate central neurons Brain Research. 325: 313-316. PMID 3978424 DOI: 10.1016/0006-8993(85)90330-0  0.547
1985 Chesler M, Nicholson C. Organization of the filum terminale in the frog Journal of Comparative Neurology. 239: 431-444. PMID 2864365 DOI: 10.1002/Cne.902390409  0.56
1980 Nicholson C. Measurement of extracellular ions in the brain Trends in Neurosciences. 3: 216-218. DOI: 10.1016/0166-2236(80)90081-8  0.34
1979 Nicholson C, Phillips JM, Gardner-Medwin AR. Diffusion from an iontophoretic point source in the brain: role of tortuosity and volume fraction. Brain Research. 169: 580-4. PMID 445169 DOI: 10.1016/0006-8993(79)90408-6  0.396
1976 Kraig RP, Nicholson C. Sodium liquid ion exchanger microelectrode used to measure large extracellular sodium transients Science. 194: 725-726. PMID 982036 DOI: 10.1126/Science.982036  0.332
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