Frank Schweizer - Publications

Affiliations: 
Chemistry University of Manitoba, Winnipeg, Manitoba, Canada 
Area:
Organic Chemistry

92 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ogunsina M, Samadder P, Idowu T, Nachtigal M, Schweizer F, Arthur G. Syntheses of L-Rhamnose-Linked Amino Glycerolipids and Their Cytotoxic Activities against Human Cancer Cells. Molecules (Basel, Switzerland). 25. PMID 32012953 DOI: 10.3390/Molecules25030566  0.326
2020 Zhanel GG, Esquivel J, Zelenitsky S, Lawrence CK, Adam HJ, Golden A, Hink R, Berry L, Schweizer F, Zhanel MA, Bay D, Lagacé-Wiens PRS, Walkty AJ, Lynch JP, Karlowsky JA. Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent. Drugs. PMID 31970713 DOI: 10.1007/S40265-020-01257-4  0.357
2020 Idowu T, Zhanel GG, Schweizer F. A Dimer, but not Monomer, of Tobramycin Potentiates Ceftolozane against MDR/XDR and Delays Resistance Development. Antimicrobial Agents and Chemotherapy. PMID 31907191 DOI: 10.1128/Aac.02055-19  0.37
2020 Nachtigal MW, Schweizer F, Arthur G. Abstract A56: Novel L-sugar linked glycosylated antitumor ether lipids for killing platinum-resistant human epithelial ovarian cancer cells Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Ovca19-A56  0.319
2019 Idowu T, Ammeter D, Rossong H, Zhanel GG, Schweizer FM. Homodimeric Tobramycin Adjuvant Repurposes Novobiocin as an Effective Antibacterial Agent against Gram-negative Bacteria. Journal of Medicinal Chemistry. PMID 31557020 DOI: 10.1021/Acs.Jmedchem.9B00876  0.351
2019 Ammeter D, Idowu T, Zhanel GG, Schweizer F. Development of a nebramine-cyclam conjugate as an antibacterial adjuvant to potentiate β-lactam antibiotics against multidrug-resistant P. aeruginosa. The Journal of Antibiotics. PMID 31420586 DOI: 10.1038/S41429-019-0221-9  0.359
2019 Domalaon R, Ammeter D, Brizuela M, Gorityala BK, Zhanel GG, Schweizer F. Repurposed Antimicrobial Combination Therapy: Tobramycin-Ciprofloxacin Hybrid Augments Activity of the Anticancer Drug Mitomycin C Against Multidrug-Resistant Gram-Negative Bacteria. Frontiers in Microbiology. 10: 1556. PMID 31354660 DOI: 10.3389/Fmicb.2019.01556  0.355
2019 Idowu T, Ammeter D, Arthur G, Zhanel GG, Schweizer F. Potentiation of β-lactam antibiotics and β-lactam/β-lactamase inhibitor combinations against MDR and XDR Pseudomonas aeruginosa using non-ribosomal tobramycin-cyclam conjugates. The Journal of Antimicrobial Chemotherapy. PMID 31139830 DOI: 10.1093/Jac/Dkz228  0.32
2019 Yang X, Ammeter D, Idowu T, Domalaon R, Brizuela M, Okunnu O, Bi L, Guerrero YA, Zhanel GG, Kumar A, Schweizer F. Amphiphilic nebramine-based hybrids Rescue legacy antibiotics from intrinsic resistance in multidrug-resistant Gram-negative bacilli. European Journal of Medicinal Chemistry. 175: 187-200. PMID 31078866 DOI: 10.1016/J.Ejmech.2019.05.003  0.375
2019 Berry L, Domalaon R, Brizuela M, Zhanel GG, Schweizer F. Polybasic peptide-levofloxacin conjugates potentiate fluoroquinolones and other classes of antibiotics against multidrug-resistant Gram-negative bacteria. Medchemcomm. 10: 517-527. PMID 31057731 DOI: 10.1039/C9Md00051H  0.416
2019 Domalaon R, Okunnu O, Zhanel GG, Schweizer F. Synergistic combinations of anthelmintic salicylanilides oxyclozanide, rafoxanide, and closantel with colistin eradicates multidrug-resistant colistin-resistant Gram-negative bacilli. The Journal of Antibiotics. PMID 31028351 DOI: 10.1038/S41429-019-0186-8  0.342
2019 Idowu T, Arthur G, Zhanel GG, Schweizer F. Heterodimeric Rifampicin-Tobramycin conjugates break intrinsic resistance of Pseudomonas aeruginosa to doxycycline and chloramphenicol in vitro and in a Galleria mellonella in vivo model. European Journal of Medicinal Chemistry. 174: 16-32. PMID 31022550 DOI: 10.1016/J.Ejmech.2019.04.034  0.345
2019 Domalaon R, De Silva PM, Kumar A, Zhanel GG, Schweizer F. The Anthelmintic Drug Niclosamide Synergizes with Colistin and Reverses Colistin Resistance in Gram-Negative Bacilli. Antimicrobial Agents and Chemotherapy. 63. PMID 30917988 DOI: 10.1128/Aac.02574-18  0.342
2019 Hada N, Umeda Y, Kumada H, Shimazaki Y, Yamano K, Schweizer F, Oshima N, Takeda T, Kiuchi F. Synthesis of the Non Reducing End Oligosaccharides of Glycosphingolipids from Ascaris suum. Chemical & Pharmaceutical Bulletin. 67: 143-154. PMID 30713275 DOI: 10.1248/Cpb.C18-00768  0.315
2019 Zhanel GG, Golden AR, Zelenitsky S, Wiebe K, Lawrence CK, Adam HJ, Idowu T, Domalaon R, Schweizer F, Zhanel MA, Lagacé-Wiens PRS, Walkty AJ, Noreddin A, Lynch Iii JP, Karlowsky JA. Cefiderocol: A Siderophore Cephalosporin with Activity Against Carbapenem-Resistant and Multidrug-Resistant Gram-Negative Bacilli. Drugs. PMID 30712199 DOI: 10.1007/S40265-019-1055-2  0.378
2018 Domalaon R, Brizuela M, Eisner B, Findlay B, Zhanel GG, Schweizer F. Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria. Amino Acids. PMID 30392097 DOI: 10.1007/S00726-018-2673-9  0.415
2018 Domalaon R, Berry L, Tays Q, Zhanel GG, Schweizer F. Development of dilipid polymyxins: Investigation on the effect of hydrophobicity through its fatty acyl component. Bioorganic Chemistry. 80: 639-648. PMID 30053708 DOI: 10.1016/J.Bioorg.2018.07.018  0.369
2018 Yang X, Domalaon R, Lyu Y, Zhanel GG, Schweizer F. Tobramycin-Linked Efflux Pump Inhibitor Conjugates Synergize Fluoroquinolones, Rifampicin and Fosfomycin against Multidrug-Resistant . Journal of Clinical Medicine. 7. PMID 29932132 DOI: 10.3390/Jcm7070158  0.345
2018 Domalaon R, Idowu T, Zhanel GG, Schweizer F. Antibiotic Hybrids: the Next Generation of Agents and Adjuvants against Gram-Negative Pathogens? Clinical Microbiology Reviews. 31. PMID 29540434 DOI: 10.1128/Cmr.00077-17  0.358
2018 Domalaon R, Sanchak Y, Koskei LC, Lyu Y, Zhanel GG, Arthur G, Schweizer F. Short proline-rich lipopeptide potentiates minocycline and rifampicin against multidrug- and extensively drug-resistant. Antimicrobial Agents and Chemotherapy. PMID 29437631 DOI: 10.1128/Aac.02374-17  0.378
2017 Zhanel GG, Lawrence CK, Adam H, Schweizer F, Zelenitsky S, Zhanel M, Lagacé-Wiens PRS, Walkty A, Denisuik A, Golden A, Gin AS, Hoban DJ, Lynch JP, Karlowsky JA. Imipenem-Relebactam and Meropenem-Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations. Drugs. PMID 29230684 DOI: 10.1007/S40265-017-0851-9  0.374
2017 Lyu Y, Domalaon R, Yang X, Schweizer F. Amphiphilic lysine conjugated to tobramycin synergizes legacy antibiotics against wild-type and multidrug-resistant Pseudomonas aeruginosa. Biopolymers. PMID 29205266 DOI: 10.1002/Bip.23091  0.399
2017 Idowu T, Schweizer F. Ubiquitous Nature of Fluoroquinolones: The Oscillation between Antibacterial and Anticancer Activities. Antibiotics (Basel, Switzerland). 6. PMID 29112154 DOI: 10.3390/Antibiotics6040026  0.306
2017 Lyu Y, Yang X, Goswami S, Gorityala BK, Idowu T, Domalaon R, Zhanel GG, Shan A, Schweizer FM. Amphiphilic tobramycin-lysine conjugates sensitize multidrug resistant Gram-negative bacteria to rifampicin and minocycline. Journal of Medicinal Chemistry. PMID 28409644 DOI: 10.1021/Acs.Jmedchem.6B01742  0.366
2017 Yang X, Goswami S, Gorityala BK, Domalaon R, Lyu Y, Kumar A, Zhanel GG, Schweizer FM. A tobramycin vector enhances synergy and efficacy of efflux pump inhibitors against multidrug-resistant Gram-negative bacteria. Journal of Medicinal Chemistry. PMID 28399372 DOI: 10.1021/Acs.Jmedchem.7B00156  0.355
2017 Kanaya T, Mashio R, Watanabe T, Schweizer F, Hada N. Synthesis of glycosphingolipids from the fungus Hirsutella rhossiliensis Tetrahedron. 73: 6847-6855. DOI: 10.1016/J.Tet.2017.10.034  0.305
2016 Zhanel GG, Hartel E, Adam H, Zelenitsky S, Zhanel MA, Golden A, Schweizer F, Gorityala B, Lagacé-Wiens PR, Walkty AJ, Gin AS, Hoban DJ, Lynch JP, Karlowsky JA. Solithromycin: A Novel Fluoroketolide for the Treatment of Community-Acquired Bacterial Pneumonia. Drugs. PMID 27909995 DOI: 10.1007/S40265-016-0667-Z  0.324
2016 McLellan M, Doyle MG, Bodnar ED, Lopez PG, Domalaon R, Roy R, Cordova K, Schweizer F, Perreault H. Multiplex Azido-Group Isotopic Capture (MAGIC) Beads: Selective Analysis of Azido Compounds Using a Propargyl-based Cleavable Linker, a Proof of Concept. Rapid Communications in Mass Spectrometry : Rcm. PMID 27650360 DOI: 10.1002/Rcm.7744  0.337
2016 Gorityala BK, Guchhait G, Goswami S, Fernando DM, Kumar A, Zhanel GG, Schweizer FM. Hybrid antibiotic overcomes resistance in P. aeruginosa by enhancing outer membrane penetration and reducing efflux. Journal of Medicinal Chemistry. PMID 27524179 DOI: 10.1021/Acs.Jmedchem.6B00867  0.338
2016 Domalaon R, Findlay B, Ogunsina M, Arthur G, Schweizer F. Ultrashort cationic lipopeptides and lipopeptoids: Evaluation and mechanistic insights against epithelial cancer cells. Peptides. PMID 27486068 DOI: 10.1016/J.Peptides.2016.07.007  0.343
2016 Hada N, Kitamura A, Yamano K, Schweizer F, Kiuchi F. Synthesis and Antigenicity against Human Sera of a Biotin-Labeled Oligosaccharide Portion of a Glycosphingolipid from the Parasite Echinococcus multilocularis. Chemical & Pharmaceutical Bulletin. 64: 865-73. PMID 27373642 DOI: 10.1248/Cpb.C16-00211  0.317
2016 Zhanel GG, Cheung D, Adam H, Zelenitsky S, Golden A, Schweizer F, Gorityala B, Lagacé-Wiens PR, Walkty A, Gin AS, Hoban DJ, Karlowsky JA. Review of Eravacycline, a Novel Fluorocycline Antibacterial Agent. Drugs. 76: 567-88. PMID 26863149 DOI: 10.1007/S40265-016-0545-8  0.333
2016 Domalaon R, Zhanel GG, Schweizer F. Short Antimicrobial Peptides and Peptide Scaffolds as Promising Antibacterial Agents. Current Topics in Medicinal Chemistry. 16: 1217-30. PMID 26369812 DOI: 10.2174/1568026615666150915112459  0.38
2016 Idowu T, Samadder P, Arthur G, Schweizer F. Design, synthesis and antitumor properties of glycosylated antitumor ether lipid (GAEL)- chlorambucil-hybrids. Chemistry and Physics of Lipids. 194: 139-48. PMID 26188768 DOI: 10.1016/J.Chemphyslip.2015.07.003  0.304
2016 Bera S, Mondal D, Palit S, Schweizer F. Structural modifications of the neomycin class of aminoglycosides Medchemcomm. 7: 1499-1534. DOI: 10.1039/C6Md00079G  0.654
2015 Gorityala BK, Guchhait G, Fernando DM, Deo S, McKenna SA, Zhanel GG, Kumar A, Schweizer F. Adjuvants Based on Hybrid Antibiotics Overcome Resistance in Pseudomonas aeruginosa and Enhance Fluoroquinolone Efficacy. Angewandte Chemie (International Ed. in English). PMID 26610184 DOI: 10.1002/Anie.201508330  0.38
2015 Zhanel GG, Love R, Adam H, Golden A, Zelenitsky S, Schweizer F, Gorityala B, Lagacé-Wiens PR, Rubinstein E, Walkty A, Gin AS, Gilmour M, Hoban DJ, Lynch JP, Karlowsky JA. Tedizolid: a novel oxazolidinone with potent activity against multidrug-resistant gram-positive pathogens. Drugs. 75: 253-70. PMID 25673021 DOI: 10.1007/S40265-015-0352-7  0.365
2014 Domalaon R, Yang X, O'Neil J, Zhanel GG, Mookherjee N, Schweizer F. Structure-activity relationships in ultrashort cationic lipopeptides: the effects of amino acid ring constraint on antibacterial activity. Amino Acids. 46: 2517-30. PMID 25069750 DOI: 10.1007/S00726-014-1806-Z  0.388
2014 Samadder P, Xu Y, Schweizer F, Arthur G. Cytotoxic properties of D-gluco-, D-galacto- and D-manno-configured 2-amino-2-deoxy-glycerolipids against epithelial cancer cell lines and BT-474 breast cancer stem cells. European Journal of Medicinal Chemistry. 78: 225-35. PMID 24681987 DOI: 10.1016/J.Ejmech.2014.03.057  0.321
2014 Zhanel GG, Chung P, Adam H, Zelenitsky S, Denisuik A, Schweizer F, Lagacé-Wiens PR, Rubinstein E, Gin AS, Walkty A, Hoban DJ, Lynch JP, Karlowsky JA. Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli. Drugs. 74: 31-51. PMID 24352909 DOI: 10.1007/S40265-013-0168-2  0.368
2013 Ogunsina M, Pan H, Samadder P, Arthur G, Schweizer F. Structure activity relationships of N-linked and diglycosylated glucosamine-based antitumor glycerolipids. Molecules (Basel, Switzerland). 18: 15288-304. PMID 24335578 DOI: 10.3390/Molecules181215288  0.326
2013 Zhanel GG, Lawson CD, Adam H, Schweizer F, Zelenitsky S, Lagacé-Wiens PR, Denisuik A, Rubinstein E, Gin AS, Hoban DJ, Lynch JP, Karlowsky JA. Ceftazidime-avibactam: a novel cephalosporin/β-lactamase inhibitor combination. Drugs. 73: 159-77. PMID 23371303 DOI: 10.1007/S40265-013-0013-7  0.379
2013 Xu Y, Ogunsina M, Samadder P, Arthur G, Schweizer F. Structure-activity relationships of glucosamine-derived glycerolipids: the role of the anomeric linkage, the cationic charge and the glycero moiety on the antitumor activity. Chemmedchem. 8: 511-20. PMID 23322648 DOI: 10.1002/Cmdc.201200489  0.326
2012 Kanaya T, Schweizer F, Takeda T, Kiuchi F, Hada N. Synthetic studies on glycosphingolipids from protostomia phyla: synthesis of glycosphingolipids and related carbohydrate moieties from the parasite Schistosoma mansoni. Carbohydrate Research. 361: 55-72. PMID 22982172 DOI: 10.1016/J.Carres.2012.08.008  0.302
2012 Bera S, Dhondikubeer R, Findlay B, Zhanel GG, Schweizer F. Synthesis and antibacterial activities of amphiphilic neomycin B-based bilipid conjugates and fluorinated neomycin B-based lipids. Molecules (Basel, Switzerland). 17: 9129-41. PMID 22858839 DOI: 10.3390/Molecules17089129  0.327
2012 Koizumi A, Yamano K, Tsuchiya T, Schweizer F, Kiuchi F, Hada N. Synthesis, antigenicity against human sera and structure-activity relationships of carbohydrate moieties from Toxocara larvae and their analogues. Molecules (Basel, Switzerland). 17: 9023-42. PMID 22847142 DOI: 10.3390/Molecules17089023  0.34
2012 Findlay B, Szelemej P, Zhanel GG, Schweizer F. Guanidylation and tail effects in cationic antimicrobial lipopeptoids. Plos One. 7: e41141. PMID 22844435 DOI: 10.1371/Journal.Pone.0041141  0.387
2012 Dhondikubeer R, Bera S, Zhanel GG, Schweizer F. Antibacterial activity of amphiphilic tobramycin. The Journal of Antibiotics. 65: 495-8. PMID 22781280 DOI: 10.1038/Ja.2012.59  0.379
2012 Findlay B, Zhanel GG, Schweizer F. Investigating the antimicrobial peptide 'window of activity' using cationic lipopeptides with hydrocarbon and fluorinated tails. International Journal of Antimicrobial Agents. 40: 36-42. PMID 22578748 DOI: 10.1016/J.Ijantimicag.2012.03.013  0.358
2012 Zhanel GG, Lawson CD, Zelenitsky S, Findlay B, Schweizer F, Adam H, Walkty A, Rubinstein E, Gin AS, Hoban DJ, Lynch JP, Karlowsky JA. Comparison of the next-generation aminoglycoside plazomicin to gentamicin, tobramycin and amikacin. Expert Review of Anti-Infective Therapy. 10: 459-73. PMID 22512755 DOI: 10.1586/Eri.12.25  0.372
2012 Zhanel GG, Schweizer F, Karlowsky JA. Oritavancin: mechanism of action. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 54: S214-9. PMID 22431851 DOI: 10.1093/Cid/Cir920  0.384
2012 Findlay B, Zhanel GG, Schweizer F. Neomycin-phenolic conjugates: polycationic amphiphiles with broad-spectrum antibacterial activity, low hemolytic activity and weak serum protein binding. Bioorganic & Medicinal Chemistry Letters. 22: 1499-503. PMID 22285320 DOI: 10.1016/J.Bmcl.2012.01.025  0.378
2012 Naziga EB, Schweizer F, Wetmore SD. Conformational study of the hydroxyproline-O-glycosidic linkage: sugar-peptide orientation and prolyl amide isomerization in (α/β)-galactosylated 4(R/S)-hydroxyproline. The Journal of Physical Chemistry. B. 116: 860-71. PMID 22148719 DOI: 10.1021/Jp207479Q  0.348
2011 Bera S, Zhanel GG, Schweizer F. Synthesis and antibacterial activity of amphiphilic lysine-ligated neomycin B conjugates. Carbohydrate Research. 346: 560-8. PMID 21353205 DOI: 10.1016/J.Carres.2011.01.015  0.356
2011 Mondal D, Zhanel GG, Schweizer F. Synthesis and antibacterial properties of carbohydrate-templated lysine surfactants. Carbohydrate Research. 346: 588-94. PMID 21316648 DOI: 10.1016/J.Carres.2011.01.025  0.66
2011 Fujita Y, Ohshima N, Hasegawa A, Schweizer F, Takeda T, Kiuchi F, Hada N. Synthesis, inhibitory effects on nitric oxide and structure-activity relationships of a glycosphingolipid from the marine sponge Aplysinella rhax and its analogues. Molecules (Basel, Switzerland). 16: 637-51. PMID 21242943 DOI: 10.3390/Molecules16010637  0.348
2010 Zhanel GG, DeCorby M, Adam H, Mulvey MR, McCracken M, Lagacé-Wiens P, Nichol KA, Wierzbowski A, Baudry PJ, Tailor F, Karlowsky JA, Walkty A, Schweizer F, Johnson J, et al. Prevalence of antimicrobial-resistant pathogens in Canadian hospitals: results of the Canadian Ward Surveillance Study (CANWARD 2008). Antimicrobial Agents and Chemotherapy. 54: 4684-93. PMID 20805395 DOI: 10.1128/AAC.00469-10  0.309
2010 Findlay B, Zhanel GG, Schweizer F. Cationic amphiphiles, a new generation of antimicrobials inspired by the natural antimicrobial peptide scaffold. Antimicrobial Agents and Chemotherapy. 54: 4049-58. PMID 20696877 DOI: 10.1128/Aac.00530-10  0.412
2010 Mondal D, Schweizer F. Synthesis of allose-templated hydroxyornithine and hydroxyarginine analogs. Carbohydrate Research. 345: 1533-40. PMID 20478556 DOI: 10.1016/J.Carres.2010.04.017  0.681
2010 Zhanel GG, Calic D, Schweizer F, Zelenitsky S, Adam H, Lagacé-Wiens PR, Rubinstein E, Gin AS, Hoban DJ, Karlowsky JA. New lipoglycopeptides: a comparative review of dalbavancin, oritavancin and telavancin. Drugs. 70: 859-86. PMID 20426497 DOI: 10.2165/11534440-000000000-00000  0.375
2010 Bera S, Zhanel GG, Schweizer F. Evaluation of amphiphilic aminoglycoside-peptide triazole conjugates as antibacterial agents. Bioorganic & Medicinal Chemistry Letters. 20: 3031-5. PMID 20413307 DOI: 10.1016/J.Bmcl.2010.03.116  0.361
2010 Bera S, Zhanel GG, Schweizer F. Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity. Journal of Medicinal Chemistry. 53: 3626-31. PMID 20373816 DOI: 10.1021/Jm1000437  0.371
2010 Owens NW, Stetefeld J, Lattová E, Schweizer F. Contiguous O-galactosylation of 4(R)-hydroxy-l-proline residues forms very stable polyproline II helices. Journal of the American Chemical Society. 132: 5036-42. PMID 20334378 DOI: 10.1021/Ja905724D  0.312
2010 Bera S, Zhanel GG, Schweizer F. Antibacterial activity of guanidinylated neomycin B- and kanamycin A-derived amphiphilic lipid conjugates. The Journal of Antimicrobial Chemotherapy. 65: 1224-7. PMID 20332193 DOI: 10.1093/Jac/Dkq083  0.331
2010 Schweizer F, Otter A, Hindsgaul O. ChemInform Abstract: Synthesis of Sugar-Fused GABA Analogues. Cheminform. 33: no-no. DOI: 10.1002/chin.200208215  0.422
2009 Schweizer F. Cationic amphiphilic peptides with cancer-selective toxicity. European Journal of Pharmacology. 625: 190-4. PMID 19835863 DOI: 10.1016/J.Ejphar.2009.08.043  0.33
2009 Owens NW, Lee A, Marat K, Schweizer F. The implications of (2S,4S)-hydroxyproline 4-O-glycosylation for prolyl amide isomerization. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 10649-57. PMID 19739208 DOI: 10.1002/Chem.200900844  0.312
2009 Zhanel GG, Sniezek G, Schweizer F, Zelenitsky S, Lagacé-Wiens PR, Rubinstein E, Gin AS, Hoban DJ, Karlowsky JA. Ceftaroline: a novel broad-spectrum cephalosporin with activity against meticillin-resistant Staphylococcus aureus. Drugs. 69: 809-31. PMID 19441869 DOI: 10.2165/00003495-200969070-00003  0.349
2009 Zhang K, Teklebrhan RB, Schreckenbach G, Wetmore S, Schweizer F. Intramolecular hydrogen bond-controlled prolyl amide isomerization in glucosyl 3'(S)-hydroxy-5'-hydroxymethylproline hybrids: influence of a C-5'-hydroxymethyl substituent on the thermodynamics and kinetics of prolyl amide cis/trans isomerization. The Journal of Organic Chemistry. 74: 3735-43. PMID 19354261 DOI: 10.1021/Jo9003458  0.304
2009 Serrano GN, Zhanel GG, Schweizer F. Antibacterial activity of ultrashort cationic lipo-beta-peptides. Antimicrobial Agents and Chemotherapy. 53: 2215-7. PMID 19237652 DOI: 10.1128/Aac.01100-08  0.381
2009 Zhang K, Schweizer F. Design and synthesis of glucose-templated proline-lysine chimera: polyfunctional amino acid chimera with high prolyl cis amide rotamer population. Carbohydrate Research. 344: 576-85. PMID 19185292 DOI: 10.1016/J.Carres.2008.12.024  0.346
2008 Bera S, Zhanel GG, Schweizer F. Design, synthesis, and antibacterial activities of neomycin-lipid conjugates: polycationic lipids with potent gram-positive activity. Journal of Medicinal Chemistry. 51: 6160-4. PMID 18778047 DOI: 10.1021/Jm800345U  0.379
2008 Zhanel GG, Lam A, Schweizer F, Thomson K, Walkty A, Rubinstein E, Gin AS, Hoban DJ, Noreddin AM, Karlowsky JA. Ceftobiprole: a review of a broad-spectrum and anti-MRSA cephalosporin. American Journal of Clinical Dermatology. 9: 245-54. PMID 18572975 DOI: 10.2165/00128071-200809040-00004  0.343
2008 Zhang K, Mondal D, Zhanel GG, Schweizer F. Synthesis of glucose-templated lysine analogs and incorporation into the antimicrobial dipeptide sequence kW-OBn. Carbohydrate Research. 343: 1644-52. PMID 18452902 DOI: 10.1016/J.Carres.2008.04.018  0.672
2008 Mondal D, Schweizer F. Alkylation reactions using a galactose-based β-keto ester enolate and conversion into β-C-galactosides Synlett. 2475-2478. DOI: 10.1055/S-2008-1078176  0.636
2007 Owens NW, Braun C, O'Neil JD, Marat K, Schweizer F. Effects of glycosylation of (2S,4R)-4-hydroxyproline on the conformation, kinetics, and thermodynamics of prolyl amide isomerization. Journal of the American Chemical Society. 129: 11670-1. PMID 17764180 DOI: 10.1021/Ja073488D  0.352
2007 Owens NW, Braun C, Schweizer F. Tuning of the prolyl trans/cis-amide rotamer population by use of C-glucosylproline hybrids. The Journal of Organic Chemistry. 72: 4635-43. PMID 17536863 DOI: 10.1021/Jo0700833  0.375
2007 Penner M, Schweizer F. Ritter-based glycoconjugation of amino acids and peptides--access to novel glycoconjugates displaying a beta-amide linkage between amino acid and sugar moiety. Carbohydrate Research. 342: 7-15. PMID 17134683 DOI: 10.1016/J.Carres.2006.11.006  0.351
2007 Zhang K, Wang J, Sun Z, Nguyen DH, Schweizer F. Synthesis of sugar-lysine chimera with integrated gluco-configured 1,3-hydroxyamine motif Synlett. 239-242. DOI: 10.1055/S-2007-968002  0.358
2006 Schweizer F, Hindsgaul O. Synthesis of a galacto-configured C-ketoside-based gamma-sugar-amino acid and its use in peptide coupling reactions. Carbohydrate Research. 341: 1730-6. PMID 16616901 DOI: 10.1016/J.Carres.2006.03.006  0.553
2005 Zhang K, Schweizer F. Synthesis of spirocyclic glucose-proline hybrids (GlcProHs) Synlett. 3111-3115. DOI: 10.1055/S-2005-922768  0.334
2005 Penner M, Taylor D, Desautels D, Marat K, Schweizer F. Access to unnatural glycosyl amino acid building blocks via a one-pot Ritter reaction Synlett. 212-216. DOI: 10.1055/S-2004-837204  0.334
2004 Schweizer F, Hindsgaul O, Palcic MM. Synthesis of internally fluorescence-quenched sugar nucleotides Synlett. 1784-1788. DOI: 10.1055/S-2004-829563  0.501
2003 Schweizer F. Unusual amino acids accessed through sugar-amino acid hybrids and incorporation into biologically active peptides Trends in Glycoscience and Glycotechnology. 15: 315-328. DOI: 10.4052/Tigg.15.315  0.33
2002 Schweizer F. Glycosamino acids: building blocks for combinatorial synthesis-implications for drug discovery. Angewandte Chemie (International Ed. in English). 41: 231-53. PMID 12491402 DOI: 10.1002/1521-3773(20020118)41:2<230::Aid-Anie230>3.0.Co;2-L  0.352
2002 Lohse A, Schweizer F, Hindsgaul O. Synthesis of a 56 component library of sugar beta-peptides. Combinatorial Chemistry & High Throughput Screening. 5: 389-94. PMID 12180904 DOI: 10.2174/1386207023330228  0.543
2001 Schweizer F, Inazu T. Chain extension of sugar δ-lactones with the enolate of tert-butyl bromoacetate and elaboration into functionalized C-ketosides, C-glycosides, and C-glucosyl glycines Organic Letters. 3: 4115-4118. PMID 11735598 DOI: 10.1021/Ol0102343  0.31
2001 Schweizer F, Otter A, Hindsgaul O. Synthesis of sugar-fused GABA-analogs Synlett. 1743-1746. DOI: 10.1055/S-2001-18097  0.474
2001 Schweizer F, Lohse A, Otter A, Hindsgaul O. One pot conversion of ketoses into sugar β-peptides via a ritter reaction Synlett. 1434-1436. DOI: 10.1055/S-2001-16797  0.52
1999 Schweizer F, Hindsgaul O. Combinatorial synthesis of carbohydrates. Current Opinion in Chemical Biology. 3: 291-8. PMID 10359718 DOI: 10.1016/S1367-5931(99)80045-3  0.509
1998 Schweizer F, Jiao H, Hindsgaul O, Wong WY, Irvin RT. Interaction between the pili of Pseudomonas aeruginosa PAK and its carbohydrate receptor beta-D-GalNAc(1-->4)beta-D-Gal analogs. Canadian Journal of Microbiology. 44: 307-11. PMID 9606914 DOI: 10.1139/Cjm-44-3-307  0.467
1995 Lehmann J, Schweizer F, Weitzel UP. Synthesis of photolabile mono- and di-valent α-d-mannoside-6-phosphates as chemically modifying probes for mannose-6-phosphate-receptors Carbohydrate Research. 270: 181-189. DOI: 10.1016/0008-6215(94)00001-V  0.303
Show low-probability matches.