Haian Fu - Publications

Affiliations: 
Emory University, Atlanta, GA 
Area:
Biochemistry, Cell Biology, Pharmacology

196 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bai L, Li X, Yang Y, Zhao R, White EZ, Danaher A, Bowen NJ, Hinton CV, Cook N, Li D, Wu AY, Qui M, Du Y, Fu H, Kucuk O, et al. Bromocriptine monotherapy overcomes prostate cancer chemoresistance in preclinical models. Translational Oncology. 34: 101707. PMID 37271121 DOI: 10.1016/j.tranon.2023.101707  0.309
2022 Puckett MC, Goldman EH, Cockrell LM, Huang B, Kasinski AL, Du Y, Wang CY, Lin A, Ichijo H, Khuri F, Fu H. Correction for Puckett et al., "Integration of Apoptosis Signal-Regulating Kinase 1-Mediated Stress Signaling with the Akt/Protein Kinase B-IκB Kinase Cascade". Molecular and Cellular Biology. e0028222. PMID 36036612 DOI: 10.1128/mcb.00282-22  0.787
2021 Yang X, Fan D, Troha AH, Ahn HM, Qian K, Liang B, Du Y, Fu H, Ivanov AA. Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. Bioorganic & Medicinal Chemistry. 45: 116324. PMID 34333394 DOI: 10.1016/j.bmc.2021.116324  0.351
2021 Li X, Gera L, Zhang S, Chen Y, Lou L, Wilson LM, Xie ZR, Sautto G, Liu D, Danaher A, Mamouni K, Yang Y, Du Y, Fu H, Kucuk O, et al. Pharmacological inhibition of noncanonical EED-EZH2 signaling overcomes chemoresistance in prostate cancer. Theranostics. 11: 6873-6890. PMID 34093859 DOI: 10.7150/thno.49235  0.305
2020 Chen S, Feng X, Chen X, Zhuang Z, Xiao J, Fu H, Klein JD, Wang XH, Hoover RS, Eaton DC, Cai H. 14-3-3 gamma, a novel regulator of the large-conductance Ca-activated K channels. American Journal of Physiology. Renal Physiology. PMID 32463725 DOI: 10.1152/Ajprenal.00584.2019  0.408
2019 Gonzalez-Pecchi V, Kwan AK, Doyle S, Ivanov AA, Du Y, Fu H. NSD3S stabilizes MYC through hindering its interaction with FBXW7. Journal of Molecular Cell Biology. PMID 31638140 DOI: 10.1093/Jmcb/Mjz098  0.41
2019 Chen G, Luo Y, Warncke K, Sun Y, Yu DS, Fu H, Behera M, Ramalingam SS, Doetsch PW, Duong DM, Lammers M, Curran WJ, Deng X. Acetylation regulates ribonucleotide reductase activity and cancer cell growth. Nature Communications. 10: 3213. PMID 31324785 DOI: 10.1038/S41467-019-11214-9  0.302
2019 Yang X, Cao W, Wang X, Zhang X, Zhang W, Li Z, Fu H. Down-regulation of 14-3-3zeta reduces proliferation and increases apoptosis in human glioblastoma. Cancer Gene Therapy. PMID 31068674 DOI: 10.1038/S41417-019-0097-7  0.364
2019 Yang X, Du Y, Fu H, Ivanov AA. Abstract 374: Discovery and targeting MKK3-MYC protein-protein interaction for therapeutic interrogation in cancer Cancer Research. 79: 374-374. DOI: 10.1158/1538-7445.Sabcs18-374  0.463
2018 Mo X, Tang C, Niu Q, Ma T, Du Y, Fu H. HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers. Cell Chemical Biology. PMID 30639259 DOI: 10.1016/J.Chembiol.2018.11.011  0.33
2018 Rusnak L, Tang C, Qi Q, Mo X, Fu H. Large tumor suppressor 2, LATS2, activates JNK in a kinase-independent mechanism through ASK1. Journal of Molecular Cell Biology. PMID 30496488 DOI: 10.1093/Jmcb/Mjy061  0.524
2018 Horton JR, Woodcock CB, Chen Q, Liu X, Zhang X, Shanks J, Rai G, Mott BT, Jansen DJ, Kales SC, Henderson MJ, Cyr M, Pohida K, Hu X, Shah P, ... ... Fu H, et al. Structure-based engineering of irreversible inhibitors against histone lysine demethylase KDM5A. Journal of Medicinal Chemistry. PMID 30392349 DOI: 10.1021/Acs.Jmedchem.8B01219  0.305
2018 Mady ASA, Liao C, Bajwa N, Kump KJ, Abulwerdi FA, Lev KL, Miao L, Grigsby SM, Perdih A, Stuckey JA, Du Y, Fu H, Nikolovska-Coleska Z. Discovery of Mcl-1 inhibitors from integrated high throughput and virtual screening. Scientific Reports. 8: 10210. PMID 29976942 DOI: 10.1038/S41598-018-27899-9  0.365
2018 Chen M, Hu C, Guo Y, Jiang R, Jiang H, Zhou Y, Fu H, Wu M, Zhang X. Ophiopogonin B suppresses the metastasis and angiogenesis of A549 cells in vitro and in vivo by inhibiting the EphA2/Akt signaling pathway. Oncology Reports. PMID 29956803 DOI: 10.3892/Or.2018.6531  0.351
2018 Yang Y, Mamouni K, Li X, Chen Y, Kavuri S, Du Y, Fu H, Kucuk O, Wu D. Repositioning Dopamine D2 Receptor Agonist Bromocriptine to Enhance Docetaxel Chemotherapy and Treat Bone Metastatic Prostate Cancer. Molecular Cancer Therapeutics. PMID 29907594 DOI: 10.1158/1535-7163.Mct-17-1176  0.307
2018 Sime W, Niu Q, Abassi Y, Masoumi KC, Zarrizi R, Køhler JB, Kjellström S, Lasorsa VA, Capasso M, Fu H, Massoumi R. BAP1 induces cell death via interaction with 14-3-3 in neuroblastoma. Cell Death & Disease. 9: 458. PMID 29686263 DOI: 10.1038/S41419-018-0500-6  0.399
2018 Xiong J, Pecchi VG, Qui M, Ivanov AA, Mo X, Niu Q, Chen X, Fu H, Du Y. Development of a Time-Resolved Fluorescence Resonance Energy Transfer Ultrahigh-Throughput Screening Assay for Targeting the NSD3 and MYC Interaction. Assay and Drug Development Technologies. 16: 96-106. PMID 29634317 DOI: 10.1089/Adt.2017.835  0.402
2018 Huard DJ, Crowley VM, Du Y, Cordova RA, Sun Z, Tomlin MO, Dickey CA, Koren J, Blair L, Fu H, Blagg BSJ, Lieberman RL. Trifunctional high-throughput screen identifies promising scaffold to inhibit Grp94 and treat myocilin-associated glaucoma. Acs Chemical Biology. PMID 29402077 DOI: 10.1021/Acschembio.7B01083  0.349
2017 Ivanov AA, Revennaugh B, Rusnak L, Gonzalez-Pecchi V, Mo X, Johns MA, Du Y, Cooper LAD, Moreno CS, Khuri FR, Fu H. The OncoPPi Portal: an integrative resource to explore and prioritize protein-protein interactions for cancer target discovery. Bioinformatics (Oxford, England). PMID 29186335 DOI: 10.1093/Bioinformatics/Btx743  0.345
2017 Rusnak L, Fu H. Regulation of ASK1 signaling by scaffold and adaptor proteins. Advances in Biological Regulation. PMID 29102394 DOI: 10.1016/J.Jbior.2017.10.003  0.523
2017 Xiong F, Jiang M, Chen M, Wang X, Zhang S, Zhou J, Li K, Sheng Y, Yin L, Tang Y, Ye L, Wu M, Fu H, Zhang X. Study on Inhibitory Effect of MaiMenDong Decoction and WeiJing Decoction Combination with Cisplatin on NCI-A549 Xenograft in Nude Mice and Its Mechanism. Journal of Cancer. 8: 2449-2455. PMID 28900482 DOI: 10.7150/Jca.17720  0.339
2017 Ivanov AA, Gonzalez-Pecchi V, Khuri LF, Niu Q, Wang Y, Xu Y, Bai Y, Mo X, Prochownik EV, Johns MA, Du Y, Khuri FR, Fu H. OncoPPi-informed discovery of mitogen-activated protein kinase kinase 3 as a novel binding partner of c-Myc. Oncogene. PMID 28628118 DOI: 10.1038/Onc.2017.180  0.517
2017 Li Z, Ivanov AA, Su R, Gonzalez-Pecchi V, Qi Q, Liu S, Webber P, McMillan E, Rusnak L, Pham C, Chen X, Mo X, Revennaugh B, Zhou W, Marcus A, ... ... Fu H, et al. Corrigendum: The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies. Nature Communications. 8: 15350. PMID 28416792 DOI: 10.1038/Ncomms15350  0.301
2017 Li R, Ding C, Zhang J, Xie M, Park D, Ding Y, Chen G, Zhang G, Gilbert-Ross M, Zhou W, Marcus A, Sun SY, Chen ZG, Sica GL, Ramalingam SS, ... ... Fu H, et al. Modulation of Bax and mTOR for cancer therapeutics. Cancer Research. PMID 28381544 DOI: 10.1158/0008-5472.Can-16-2356  0.341
2017 Qi Q, Kang SS, Zhang S, Pham C, Fu H, Brat DJ, Ye K. Co-amplification of phosphoinositide 3-kinase enhancer A and cyclin-dependent kinase 4 triggers glioblastoma progression. Oncogene. PMID 28368413 DOI: 10.1038/Onc.2017.67  0.412
2017 Gilbert-Ross M, Konen J, Koo J, Shupe J, Robinson BS, Wiles WG, Huang C, Martin WD, Behera M, Smith GH, Hill CE, Rossi MR, Sica GL, Rupji M, Chen Z, ... ... Fu H, et al. Targeting adhesion signaling in KRAS, LKB1 mutant lung adenocarcinoma. Jci Insight. 2: e90487. PMID 28289710 DOI: 10.1172/Jci.Insight.90487  0.683
2017 Li Z, Ivanov AA, Su R, Gonzalez-Pecchi V, Qi Q, Liu S, Webber P, McMillan E, Rusnak L, Pham C, Chen X, Mo X, Revennaugh B, Zhou W, Marcus A, ... ... Fu H, et al. The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies. Nature Communications. 8: 14356. PMID 28205554 DOI: 10.1038/Ncomms14356  0.356
2017 Umstead M, Xiong J, Qi Q, Du Y, Fu H. Aurora kinase A interacts with H-Ras and potentiates Ras-MAPK signaling. Oncotarget. PMID 28177880 DOI: 10.18632/Oncotarget.15049  0.339
2017 Harati S, Cooper LA, Moran JD, Giuste FO, Du Y, Ivanov AA, Johns MA, Khuri FR, Fu H, Moreno CS. MEDICI: Mining Essentiality Data to Identify Critical Interactions for Cancer Drug Target Discovery and Development. Plos One. 12: e0170339. PMID 28118365 DOI: 10.1371/Journal.Pone.0170339  0.379
2017 Mo XL, Qi Q, Ivanov AA, Niu Q, Luo Y, Havel J, Goetze R, Bell S, Moreno CS, Cooper LA, Johns MA, Khuri FR, Du Y, Fu H. AKT1, LKB1, and YAP1 revealed as MYC interactors with NanoLuc-based protein-fragment complementation assay. Molecular Pharmacology. PMID 28087810 DOI: 10.1124/Mol.116.107623  0.46
2017 Li R, Ding C, Zhang J, Xie M, Park D, Ding Y, Chen G, Zhang G, Gilbert-Ross M, Zhou W, Marcus A, Sun S, Chen Z, Sica G, Ramalingam S, ... ... Fu H, et al. Abstract 2333: Modulation of Bax and mTOR for cancer therapeutics Cancer Research. 77: 2333-2333. DOI: 10.1158/1538-7445.Am2017-2333  0.343
2016 Sun L, Liu X, Fu H, Zhou W, Zhong D. 2-Deoxyglucose Suppresses ERK Phosphorylation in LKB1 and Ras Wild-Type Non-Small Cell Lung Cancer Cells. Plos One. 11: e0168793. PMID 28033353 DOI: 10.1371/Journal.Pone.0168793  0.444
2016 Gu L, Zhang H, Liu T, Zhou S, Du Y, Xiong J, Yi S, Qu CK, Fu H, Zhou M. Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment. Cancer Cell. PMID 27666947 DOI: 10.1016/J.Ccell.2016.08.015  0.405
2016 Wei P, Lin M, Wang Z, Fu H, Yang H, Jiang W, Yang ST. Metabolic engineering of Propionibacterium freudenreichii subsp. shermanii for xylose fermentation. Bioresource Technology. 219: 91-97. PMID 27479799 DOI: 10.1016/J.Biortech.2016.07.056  0.399
2016 Horton JR, Liu X, Gale M, Wu L, Shanks JR, Zhang X, Webber PJ, Bell JS, Kales SC, Mott BT, Rai G, Jansen DJ, Henderson MJ, Urban DJ, Hall MD, ... ... Fu H, et al. Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds. Cell Chemical Biology. PMID 27427228 DOI: 10.1016/J.Chembiol.2016.06.006  0.328
2016 Wu Y, Qin D, Yang H, Fu H. Evidence for the Participation of Acid-Sensing Ion Channels (ASICs) in the Antinociceptive Effect of Curcumin in a Formalin-Induced Orofacial Inflammatory Model. Cellular and Molecular Neurobiology. PMID 27383838 DOI: 10.1007/s10571-016-0399-3  0.45
2016 Zhang H, Li H, Yang H, Fu H. Iron-Catalyzed Diastereoselective Synthesis of Unnatural Chiral Amino Acid Derivatives. Organic Letters. PMID 27367820 DOI: 10.1021/Acs.Orglett.6B01493  0.391
2016 Li J, Tian H, Jiang M, Yang H, Zhao Y, Fu H. Consecutive visible-light photoredox decarboxylative couplings of adipic acid active esters with alkynyl sulfones leading to cyclic compounds. Chemical Communications (Cambridge, England). PMID 27345832 DOI: 10.1039/C6Cc04386K  0.411
2016 Zhang B, Shi Y, Gong A, Pan Z, Shi H, Yang H, Fu H, Yan Y, Zhang X, Wang M, Zhu W, Qian H, Xu W. HucMSC Exosome-Delivered 14-3-3ζ Orchestrates Self-control of the Wnt Response via Modulation of YAP during Cutaneous Regeneration. Stem Cells (Dayton, Ohio). PMID 27334574 DOI: 10.1002/stem.2432  0.512
2016 Mo XL, Fu H. BRET: NanoLuc-Based Bioluminescence Resonance Energy Transfer Platform to Monitor Protein-Protein Interactions in Live Cells. Methods in Molecular Biology (Clifton, N.J.). 1439: 263-71. PMID 27317001 DOI: 10.1007/978-1-4939-3673-1_17  0.355
2016 Jiang M, Jin Y, Yang H, Fu H. Visible-light photoredox synthesis of unnatural chiral α-amino acids. Scientific Reports. 6: 26161. PMID 27185220 DOI: 10.1038/Srep26161  0.388
2016 Gao C, Li J, Yu J, Yang H, Fu H. Visible-light photoredox synthesis of internal alkynes containing quaternary carbons. Chemical Communications (Cambridge, England). PMID 27181024 DOI: 10.1039/C6Cc01632D  0.388
2016 Chen M, Guo Y, Zhao R, Wang X, Jiang M, Fu H, Zhang X. Ophiopogonin B induces apoptosis, mitotic catastrophe and autophagy in A549 cells. International Journal of Oncology. PMID 27175570 DOI: 10.3892/Ijo.2016.3514  0.324
2016 Yang H, Fu H, Xu W, Zhang X. Exosomal non-coding RNAs: a promising cancer biomarker. Clinical Chemistry and Laboratory Medicine. PMID 27166723 DOI: 10.1515/cclm-2016-0029  0.43
2016 Dai L, Yang HL, Yan WP, Liang Z, Xiong HC, Kang XZ, Yang YB, Fu H, Fan MY, Chen KN. The equivalent efficacy of multiple operations for multiple primary lung cancer and a single operation for single primary lung cancer. Journal of Thoracic Disease. 8: 855-61. PMID 27162659 DOI: 10.21037/jtd.2016.03.42  0.406
2016 Gao J, Ma Y, Fu HL, Luo Q, Wang Z, Xiao YH, Yang H, Cui DX, Jin WL. Non-catalytic roles for TET1 protein negatively regulating neuronal differentiation through srGAP3 in neuroblastoma cells. Protein & Cell. PMID 27113584 DOI: 10.1007/s13238-016-0267-4  0.489
2016 Jiang M, Yang H, Fu H. Visible-Light Photoredox Synthesis of Chiral α-Selenoamino Acids. Organic Letters. PMID 27093481 DOI: 10.1021/Acs.Orglett.6B00489  0.395
2016 Fu H, Yang H, Zhang X, Xu W. The emerging roles of exosomes in tumor-stroma interaction. Journal of Cancer Research and Clinical Oncology. PMID 26987524 DOI: 10.1007/s00432-016-2145-0  0.464
2016 Zhu M, Wang M, Yang F, Tian Y, Cai J, Yang H, Fu H, Mao F, Zhu W, Qian H, Xu W. miR-155-5p inhibition promotes the transition of bone marrow mesenchymal stem cells to gastric cancer tissue derived MSC-like cells via NF-κB p65 activation. Oncotarget. PMID 26934326 DOI: 10.18632/oncotarget.7767  0.453
2016 Konen J, Wilkinson S, Lee B, Fu H, Zhou W, Jiang Y, Marcus AI. LKB1 kinase-dependent and -independent defects disrupt polarity and adhesion signaling to drive collagen remodeling during invasion. Molecular Biology of the Cell. PMID 26864623 DOI: 10.1091/Mbc.E15-08-0569  0.415
2016 Tian H, Yang H, Zhu C, Fu H. Transition metal-free intramolecular regioselective couplings of aliphatic and aromatic C-H bonds. Scientific Reports. 6: 19931. PMID 26822836 DOI: 10.1038/Srep19931  0.404
2016 Gilbert-Ross M, Konen J, Shupe J, Koo J, Sica GL, Ramalingam SS, Fu H, Khuri FR, Zhou W, Marcus AI. Abstract B45: An early treatment window to target FAK-dependent collective invasion in Lkb1-mutant lung adenocarcinoma Cancer Research. 76. DOI: 10.1158/1538-7445.Tummet15-B45  0.306
2016 Gilbert-Ross M, Konen J, Koo J, Shupe J, Sica GL, Chen Z, Robinson BS, Behera M, Rossi MR, Smith GH, Hill CE, Ramalingam SM, Fu H, Khuri FR, Zhou W, et al. Abstract LB-348: Developing a personalized anti-metastatic therapy to treat KRAS, LKB1-mutant lung adenocarcinoma Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-348  0.327
2016 Jin R, Liu F, Liu X, Huang H, Wilkinson SC, Zhong D, Khuri FR, Fu H, Marcus AI, He Y, Zhou W. Abstract 4770: The regulation of pre-ribosomal RNA synthesis by LKB1 Cancer Research. 76: 4770-4770. DOI: 10.1158/1538-7445.Am2016-4770  0.354
2016 Umstead M, Xiong J, Li Z, Ivanov A, Du Y, Fu H. Abstract 1892: Investigating the role of Aurora Kinase A as a positive regulator of MAPK signaling Cancer Research. 76: 1892-1892. DOI: 10.1158/1538-7445.Am2016-1892  0.427
2015 Fu H, Wang X, Wang T, Yang H, Yang T. [Risk factors for type 2 diabetes complicated with hypertension in adult residents in Liuyang]. Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences. 40: 1384-90. PMID 26739083 DOI: 10.11817/j.issn.1672-7347.2015.12.016  0.368
2015 Mo XL, Luo Y, Ivanov AA, Su R, Havel JJ, Li Z, Khuri F, Du Y, Fu H. Enabling systematic interrogation of protein-protein interactions in live cells with a versatile ultra-high-throughput biosensor platform. Journal of Molecular Cell Biology. PMID 26578655 DOI: 10.1093/Jmcb/Mjv064  0.393
2015 Yang H, Fu H, Su B, Xiang B, Xu Q, Hu C. Theoretical Study on the Catalytic Reduction Mechanism of NO by CO on Tetrahedral Rh4 Subnanocluster. The Journal of Physical Chemistry. A. PMID 26510818 DOI: 10.1021/acs.jpca.5b07713  0.392
2015 Liu F, Jin R, Liu X, Huang H, Wilkinson SC, Zhong D, Khuri FR, Fu H, Marcus A, He Y, Zhou W. LKB1 promotes cell survival by modulating TIF-IA-mediated pre-ribosomal RNA synthesis under uridine downregulated conditions. Oncotarget. PMID 26506235 DOI: 10.18632/Oncotarget.6224  0.351
2015 Zhang J, Ma M, Qin D, Huang J, Cui X, Wu Y, Yang H, Fu H, Liao C. Lung morphometry changes in prevention of airway remodeling by protocatechuic aldehyde in asthmatic mice. International Journal of Clinical and Experimental Medicine. 8: 6890-901. PMID 26221226  0.388
2015 Xu X, Xu X, Liu P, Zhu ZY, Chen J, Fu HA, Chen LL, Hu LH, Shen X. Structural basis for small molecule NDB as a selective antagonist of Farnesoid X receptor α (FXRα) in stabilizing the homodimerization of the receptor. The Journal of Biological Chemistry. PMID 26100621 DOI: 10.1074/Jbc.M114.630475  0.305
2015 Zhao R, Chen M, Jiang Z, Zhao F, Xi B, Zhang X, Fu H, Zhou K. Platycodin-D Induced Autophagy in Non-Small Cell Lung Cancer Cells via PI3K/Akt/mTOR and MAPK Signaling Pathways. Journal of Cancer. 6: 623-31. PMID 26078792 DOI: 10.7150/Jca.11291  0.398
2015 Li H, Shen LY, Yan WP, Dong B, Kang XZ, Dai L, Yang YB, Fu H, Yang HL, Zhou HT, Huang C, Liang Z, Xiong HC, Chen KN. Deregulated HOXB7 Expression Predicts Poor Prognosis of Patients with Esophageal Squamous Cell Carcinoma and Regulates Cancer Cell Proliferation In Vitro and In Vivo. Plos One. 10: e0130551. PMID 26076456 DOI: 10.1371/journal.pone.0130551  0.448
2015 Feng X, Li Z, Du Y, Fu H, Klein JD, Cai H, Sands JM, Chen G. Downregulation of urea transporter UT-A1 activity by 14-3-3 protein. American Journal of Physiology. Renal Physiology. 309: F71-8. PMID 25995111 DOI: 10.1152/Ajprenal.00546.2014  0.322
2015 Zhang H, Wang H, Yang H, Fu H. Rhodium-catalyzed denitrogenative thioacetalization of N-sulfonyl-1,2,3-triazoles with disulfides: an entry to diverse transformation of terminal alkynes. Organic & Biomolecular Chemistry. 13: 6149-53. PMID 25927418 DOI: 10.1039/C5Ob00638D  0.399
2015 Yu J, Gao C, Song Z, Yang H, Fu H. Metal-free oxysulfenylation of alkenes with 1-(arylthio)pyrrolidine-2,5-diones and alcohols. Organic & Biomolecular Chemistry. 13: 4846-50. PMID 25826752 DOI: 10.1039/C5Ob00252D  0.39
2015 Wu Y, Wu Q, Zhang H, Chen C, Chen G, Yang H, Qin D, Fu H. Lack of genetic associations between PPAR-γ gene rs1801282 polymorphism and Alzheimer's disease in general population: a meta-analysis. Gene. 563: 120-4. PMID 25770052 DOI: 10.1016/j.gene.2015.03.014  0.388
2015 Yang Q, Li W, She H, Dou J, Duong DM, Du Y, Yang SH, Seyfried NT, Fu H, Gao G, Mao Z. Stress induces p38 MAPK-mediated phosphorylation and inhibition of Drosha-dependent cell survival. Molecular Cell. 57: 721-34. PMID 25699712 DOI: 10.1016/J.Molcel.2015.01.004  0.343
2015 Zhu J, Chen M, Chen N, Ma A, Zhu C, Zhao R, Jiang M, Zhou J, Ye L, Fu H, Zhang X. Glycyrrhetinic acid induces G1‑phase cell cycle arrest in human non‑small cell lung cancer cells through endoplasmic reticulum stress pathway. International Journal of Oncology. 46: 981-8. PMID 25573651 DOI: 10.3892/Ijo.2015.2819  0.36
2015 Shi Z, Park HR, Du Y, Li Z, Cheng K, Sun SY, Li Z, Fu H, Khuri FR. Cables1 complex couples survival signaling to the cell death machinery. Cancer Research. 75: 147-58. PMID 25361894 DOI: 10.1158/0008-5472.Can-14-0036  0.484
2015 Ramachandiran S, Adon A, Guo X, Wang Y, Wang H, Chen Z, Kowalski J, Sunay UR, Young AN, Brown T, Mar JC, Du Y, Fu H, Mann KP, Natkunam Y, et al. Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-κB pathway. International Journal of Cancer. Journal International Du Cancer. 136: 2341-51. PMID 25359525 DOI: 10.1002/Ijc.29301  0.339
2015 Cooper LA, Moran JD, Li Z, Du Y, Harati S, Ivanov AA, Webber P, Havel JJ, Johns MA, Fu H, Moreno CS. Abstract PR15: Predicting the essentialities of protein-protein interactions in cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-Pr15  0.405
2014 He MF, Fu HQ, Su BF, Yang HQ, Tang JQ, Hu CW. Theoretical insight into the coordination of cyclic β-D-glucose to [Al(OH)(aq)](2+) and [Al(OH)2(aq)](1+) ions. The Journal of Physical Chemistry. B. 118: 13890-902. PMID 25405722 DOI: 10.1021/jp5060099  0.394
2014 Zhou T, Ye L, Bai Y, Sun A, Cox B, Liu D, Li Y, Liotta D, Snyder JP, Fu H, Huang B. Autophagy and apoptosis in hepatocellular carcinoma induced by EF25-(GSH)2: a novel curcumin analog. Plos One. 9: e107876. PMID 25268357 DOI: 10.1371/Journal.Pone.0107876  0.335
2014 Wu Y, Fu H, Yang H, Wang H, Zhang H, Qin D. Smooth muscle progenitor cells involved in the development of airway remodeling in a murine model of asthma. Asian Pacific Journal of Allergy and Immunology / Launched by the Allergy and Immunology Society of Thailand. 32: 203-10. PMID 25268337 DOI: 10.12932/AP0395.32.3.2014  0.377
2014 Zhang Z, Qiu L, Lin C, Yang H, Fu H, Li R, Kang YJ. Copper-dependent and -independent hypoxia-inducible factor-1 regulation of gene expression. Metallomics : Integrated Biometal Science. 6: 1889-93. PMID 25100165 DOI: 10.1039/c4mt00052h  0.447
2014 Tian H, Zhu C, Yang H, Fu H. Iron or boron-catalyzed C-H arylthiation of substituted phenols at room temperature. Chemical Communications (Cambridge, England). 50: 8875-7. PMID 24969301 DOI: 10.1039/C4Cc03600J  0.391
2014 Li Z, Park HR, Shi Z, Li Z, Pham CD, Du Y, Khuri FR, Zhang Y, Han Q, Fu H. Pro-oncogenic function of HIP-55/Drebrin-like (DBNL) through Ser269/Thr291-phospho-sensor motifs. Oncotarget. 5: 3197-209. PMID 24912570 DOI: 10.18632/Oncotarget.1900  0.396
2014 Shi L, Wang Y, Yang H, Fu H. Copper-catalyzed bis-arylations of alkenes leading to oxindole derivatives. Organic & Biomolecular Chemistry. 12: 4070-3. PMID 24817255 DOI: 10.1039/C4Ob00576G  0.392
2014 Wu Y, Fu H, Zhang H, Huang H, Chen M, Zhang L, Yang H, Qin D. Cyclin D1 (CCND1) G870A polymorphisms and cervical cancer susceptibility: a meta-analysis based on ten case-control studies. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 35: 6913-8. PMID 24737585 DOI: 10.1007/s13277-014-1929-6  0.4
2014 Havel JJ, Li Z, Cheng D, Peng J, Fu H. Nuclear PRAS40 couples the Akt/mTORC1 signaling axis to the RPL11-HDM2-p53 nucleolar stress response pathway. Oncogene. 34: 1487-98. PMID 24704832 DOI: 10.1038/Onc.2014.91  0.469
2014 Kasinski A, Dong X, Khuri FR, Boss J, Fu H. Transcriptional regulation of YWHAZ, the gene encoding 14-3-3ζ. Plos One. 9: e93480. PMID 24690670 DOI: 10.1371/Journal.Pone.0093480  0.689
2014 Zhi X, Deng M, Yang H, Gao G, Wang K, Fu H, Zhang Y, Chen D, Cui D. A novel HBV genotypes detecting system combined with microfluidic chip, loop-mediated isothermal amplification and GMR sensors. Biosensors & Bioelectronics. 54: 372-7. PMID 24292142 DOI: 10.1016/j.bios.2013.11.025  0.414
2014 Orwig SD, Chi PV, Du Y, Hill SE, Cavitt MA, Suntharalingam A, Turnage KC, Dickey CA, France S, Fu H, Lieberman RL. Ligands for glaucoma-associated myocilin discovered by a generic binding assay. Acs Chemical Biology. 9: 517-25. PMID 24279319 DOI: 10.1021/Cb4007776  0.349
2013 Zheng L, Zhang W, Jiang M, Zhang H, Xiong F, Yu Y, Chen M, Zhou J, Dai X, Tang Y, Jiang M, Wang M, Cheng G, Duan J, Yu W, ... ... Fu H, et al. Expression Profiling and Proteomic Analysis of JIN Chinese Herbal Formula in Lung Carcinoma H460 Xenografts. Evidence-Based Complementary and Alternative Medicine : Ecam. 2013: 160168. PMID 24066008 DOI: 10.1155/2013/160168  0.397
2013 Du Y, Fu RW, Lou B, Zhao J, Qui M, Khuri FR, Fu H. A time-resolved fluorescence resonance energy transfer assay for high-throughput screening of 14-3-3 protein-protein interaction inhibitors. Assay and Drug Development Technologies. 11: 367-81. PMID 23906346 DOI: 10.1089/Adt.2013.507  0.42
2013 Wang H, Zhu B, He Z, Fu H, Dai Z, Huang G, Li B, Qin D, Zhang X, Tian L, Fang W, Yang H. Deuterium-depleted water (DDW) inhibits the proliferation and migration of nasopharyngeal carcinoma cells in vitro. Biomedicine & Pharmacotherapy = Biomã©Decine & Pharmacothã©Rapie. 67: 489-96. PMID 23773852 DOI: 10.1016/j.biopha.2013.02.001  0.454
2013 Ivanov AA, Khuri FR, Fu H. Targeting protein-protein interactions as an anticancer strategy. Trends in Pharmacological Sciences. 34: 393-400. PMID 23725674 DOI: 10.1016/J.Tips.2013.04.007  0.334
2013 Jin L, Li D, Lee JS, Elf S, Alesi GN, Fan J, Kang HB, Wang D, Fu H, Taunton J, Boggon TJ, Tucker M, Gu TL, Chen ZG, Shin DM, et al. p90 RSK2 Mediates Antianoikis Signals by both Transcription-Dependent and-Independent Mechanisms Molecular and Cellular Biology. 33: 2574-2585. PMID 23608533 DOI: 10.1128/Mcb.01677-12  0.512
2013 Li Y, Wang X, Yue P, Tao H, Ramalingam SS, Owonikoko TK, Deng X, Wang Y, Fu H, Khuri FR, Sun SY. Protein phosphatase 2A and DNA-dependent protein kinase are involved in mediating rapamycin-induced Akt phosphorylation. The Journal of Biological Chemistry. 288: 13215-24. PMID 23536185 DOI: 10.1074/Jbc.M113.463679  0.448
2013 Puckett MC, Goldman EH, Cockrell LM, Huang B, Kasinski AL, Du Y, Wang CY, Lin A, Ichijo H, Khuri F, Fu H. Integration of apoptosis signal-regulating kinase 1-mediated stress signaling with the Akt/protein kinase B-IκB kinase cascade. Molecular and Cellular Biology. 33: 2252-9. PMID 23530055 DOI: 10.1128/Mcb.00047-13  0.796
2013 Yu J, Yang H, Jiang Y, Fu H. Copper-catalyzed aerobic oxidative C-H and C-C functionalization of 1-[2-(arylamino)aryl]ethanones leading to acridone derivatives. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 4271-7. PMID 23401330 DOI: 10.1002/Chem.201204169  0.397
2013 Li J, Wu LJ, Guo SS, Fu HE, Chen GN, Yang HH. Simple colorimetric bacterial detection and high-throughput drug screening based on a graphene-enzyme complex. Nanoscale. 5: 619-23. PMID 23208411 DOI: 10.1039/c2nr32704j  0.382
2013 Wang F, Yang H, Fu H, Pei Z. Efficient copper-catalyzed Michael addition of acrylic derivatives with primary alcohols in the presence of base. Chemical Communications (Cambridge, England). 49: 517-9. PMID 23192281 DOI: 10.1039/C2Cc37595H  0.379
2013 Chen M, Du Y, Qui M, Wang M, Chen K, Huang Z, Jiang M, Xiong F, Chen J, Zhou J, Jiang F, Yin L, Tang Y, Ye L, Zhan Z, ... ... Fu HΑ, et al. Ophiopogonin B-induced autophagy in non-small cell lung cancer cells via inhibition of the PI3K/Akt signaling pathway. Oncology Reports. 29: 430-6. PMID 23151908 DOI: 10.3892/Or.2012.2131  0.391
2013 Jin L, Li D, Lee J, Alesi GN, Fan J, Kang H, Wang D, Fu H, Taunton J, Boggon TJ, Tucker M, Gu T, Chen ZG, Shin DM, Khuri FR, et al. Abstract 2925: p90RSK2 coordinates pro-apoptotic and anti-apoptotic signaling pathways to protect cancer cells from anoikis. Cancer Research. 73: 2925-2925. DOI: 10.1158/1538-7445.Am2013-2925  0.48
2013 Mady A, Liao C, Abulwerdi F, Shen C, Du Y, Stuckey J, Fu H, Nikolovska-Coleska Z. Abstract 2469: Identification of novel Mcl-1 inhibitors using integrated screening approach: combining high throughput and virtual screening. Cancer Research. 73: 2469-2469. DOI: 10.1158/1538-7445.Am2013-2469  0.36
2013 Ivanov AA, Nim S, Du Y, Fu H. Abstract 2232: Computational modeling reveals druggable cavities at the MKK3 and p38 protein interaction interface. Cancer Research. 73: 2232-2232. DOI: 10.1158/1538-7445.Am2013-2232  0.395
2012 Yang HC, Fu HL, Lin YF, Rosen BP. Pathways of arsenic uptake and efflux. Current Topics in Membranes. 69: 325-58. PMID 23046656 DOI: 10.1016/B978-0-12-394390-3.00012-4  0.445
2012 Ji JS, Teng GJ, Yang HY, Song JJ, Lu CY, Fu HX. [Preparation and in vivo-in vitro evaluation of compound nanoparticles loaded with epirubicin hydrochloride and gadopentetate meglumine]. Zhonghua Yi Xue Za Zhi. 92: 1626-9. PMID 22944133  0.382
2012 Liu HZ, Gao CY, Wang XQ, Fu HX, Yang HH, Wang XP, Liu YH, Li MW, Niu ZM, Dai GY, Qi DT, Zhang Y. [Angiotensin(1-7) attenuates left ventricular dysfunction and myocardial apoptosis on rat model of adriamycin-induced dilated cardiomyopathy]. Zhonghua Xin Xue Guan Bing Za Zhi. 40: 219-24. PMID 22801267  0.401
2012 Smith SM, Min J, Ganesh T, Diebold B, Kawahara T, Zhu Y, McCoy J, Sun A, Snyder JP, Fu H, Du Y, Lewis I, Lambeth JD. Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits. Chemistry & Biology. 19: 752-63. PMID 22726689 DOI: 10.1016/J.Chembiol.2012.04.015  0.353
2012 Li J, Fu HE, Wu LJ, Zheng AX, Chen GN, Yang HH. General colorimetric detection of proteins and small molecules based on cyclic enzymatic signal amplification and hairpin aptamer probe. Analytical Chemistry. 84: 5309-15. PMID 22642720 DOI: 10.1021/ac3006186  0.437
2012 Bai Y, Zhou T, Fu H, Sun H, Huang B. 14-3-3 interacts with LKB1 via recognizing phosphorylated threonine 336 residue and suppresses LKB1 kinase function. Febs Letters. 586: 1111-9. PMID 22575644 DOI: 10.1016/J.Febslet.2012.03.018  0.486
2012 Li J, Qi XJ, Du YY, Fu HE, Chen GN, Yang HH. Efficient detection of secondary structure folded nucleic acids related to Alzheimer's disease based on junction probes. Biosensors & Bioelectronics. 36: 142-6. PMID 22560436 DOI: 10.1016/j.bios.2012.04.003  0.413
2012 Zhu S, Moore TW, Lin X, Morii N, Mancini A, Howard RB, Culver D, Arrendale RF, Reddy P, Evers TJ, Zhang H, Sica G, Chen ZG, Sun A, Fu H, et al. Synthetic curcumin analog EF31 inhibits the growth of head and neck squamous cell carcinoma xenografts. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 633-40. PMID 22532032 DOI: 10.1039/C2Ib20007D  0.301
2012 Qi Q, He K, Liu X, Pham C, Meyerkord C, Fu H, Ye K. Disrupting the PIKE-A/Akt interaction inhibits glioblastoma cell survival, migration, invasion and colony formation. Oncogene. 32: 1030-40. PMID 22450747 DOI: 10.1038/Onc.2012.109  0.478
2012 Ramachandiran S, Cain J, Liao A, He Y, Guo X, Boise LH, Fu H, Ratner L, Khoury HJ, Bernal-Mizrachi L. The Smac mimetic RMT5265.2HCL induces apoptosis in EBV and HTLV-I associated lymphoma cells by inhibiting XIAP and promoting the mitochondrial release of cytochrome C and Smac. Leukemia Research. 36: 784-90. PMID 22325366 DOI: 10.1016/J.Leukres.2011.12.024  0.33
2012 Andersen SD, Keijzers G, Rampakakis E, Engels K, Luhn P, El-Shemerly M, Nielsen FC, Du Y, May A, Bohr VA, Ferrari S, Zannis-Hadjopoulos M, Fu H, Rasmussen LJ. 14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif. Dna Repair. 11: 267-77. PMID 22222486 DOI: 10.1016/J.Dnarep.2011.11.007  0.781
2012 Qi Q, He K, Yoo MH, Chan CB, Liu X, Zhang Z, Olson JJ, Xiao G, Wang L, Mao H, Fu H, Tao H, Ramalingam SS, Sun SY, Mischel PS, et al. Acridine yellow G blocks glioblastoma growth via dual inhibition of epidermal growth factor receptor and protein kinase C kinases. The Journal of Biological Chemistry. 287: 6113-27. PMID 22215664 DOI: 10.1074/Jbc.M111.293605  0.384
2012 Havel JJ, Li Z, Fu H. Abstract 4986: Nuclear PRAS40 regulates the cellular response to nucleolar stress Cancer Research. 72: 4986-4986. DOI: 10.1158/1538-7445.Am2012-4986  0.394
2012 Li Z, Du Y, Sica G, Ramalingam SS, Gal AA, Pan L, Tighiouart MM, Khuri FRFR, Fu H. Abstract 112: An endogenous mTOR inhibitor, PRAS40, is upregulated in lung cancer and contributes to tumor cell invasion and chemoresistance Cancer Research. 72: 112-112. DOI: 10.1158/1538-7445.Am2012-112  0.366
2011 Hitosugi T, Fan J, Chung TW, Lythgoe K, Wang X, Xie J, Ge Q, Gu TL, Polakiewicz RD, Roesel JL, Chen GZ, Boggon TJ, Lonial S, Fu H, Khuri FR, et al. Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism. Molecular Cell. 44: 864-77. PMID 22195962 DOI: 10.1016/J.Molcel.2011.10.015  0.398
2011 Zhao J, Meyerkord CL, Du Y, Khuri FR, Fu H. 14-3-3 proteins as potential therapeutic targets. Seminars in Cell & Developmental Biology. 22: 705-12. PMID 21983031 DOI: 10.1016/J.Semcdb.2011.09.012  0.454
2011 Zhao J, Du Y, Horton JR, Upadhyay AK, Lou B, Bai Y, Zhang X, Du L, Li M, Wang B, Zhang L, Barbieri JT, Khuri FR, Cheng X, Fu H. Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 108: 16212-6. PMID 21908710 DOI: 10.1073/Pnas.1100012108  0.411
2011 Li L, Du Y, Chen W, Fu H, Harrison DG. A novel high-throughput screening assay for discovery of molecules that increase cellular tetrahydrobiopterin. Journal of Biomolecular Screening. 16: 836-44. PMID 21693765 DOI: 10.1177/1087057111411088  0.369
2011 Williams DM, Ecroyd H, Goodwin KL, Dai H, Fu H, Woodcock JM, Zhang L, Carver JA. NMR spectroscopy of 14-3-3ζ reveals a flexible C-terminal extension: differentiation of the chaperone and phosphoserine-binding activities of 14-3-3ζ. The Biochemical Journal. 437: 493-503. PMID 21554249 DOI: 10.1042/BJ20102178  0.328
2011 Cencic R, Desforges M, Hall DR, Kozakov D, Du Y, Min J, Dingledine R, Fu H, Vajda S, Talbot PJ, Pelletier J. Blocking eIF4E-eIF4G interaction as a strategy to impair coronavirus replication. Journal of Virology. 85: 6381-9. PMID 21507972 DOI: 10.1128/Jvi.00078-11  0.357
2011 Sun A, Moore TW, Gunther JR, Kim MS, Rhoden E, Du Y, Fu H, Snyder JP, Katzenellenbogen JA. Discovering small-molecule estrogen receptor α/coactivator binding inhibitors: high-throughput screening, ligand development, and models for enhanced potency. Chemmedchem. 6: 654-66. PMID 21365764 DOI: 10.1002/Cmdc.201000507  0.34
2011 Cencic R, Hall DR, Robert F, Du Y, Min J, Li L, Qui M, Lewis I, Kurtkaya S, Dingledine R, Fu H, Kozakov D, Vajda S, Pelletier J. Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F. Proceedings of the National Academy of Sciences of the United States of America. 108: 1046-51. PMID 21191102 DOI: 10.1073/Pnas.1011477108  0.366
2011 Puckett MC, Goldman E, Cockrell L, Khuri F, Fu H. Abstract A41: The ASK1/IKK signaling axis mediates crosstalk between inflammation and apoptosis Cancer Prevention Research. 4. DOI: 10.1158/1940-6207.Prev-11-A41  0.823
2011 Shi Z, Park HR, Du Y, Fu H, Khuri FR. Abstract 2116: The Cables1 protein complex couples survival signaling to cell death machinery Cancer Research. 71: 2116-2116. DOI: 10.1158/1538-7445.Am2011-2116  0.483
2011 Zhong D, Liu X, Fu H, Sun S, Khuri FR, Zhou W. Abstract 1058: LKB1 negatively regulates IGF-1 induced ERK phosphorylation Cancer Research. 71: 1058-1058. DOI: 10.1158/1538-7445.Am2011-1058  0.463
2011 Kasinski A, Fu H. 14-3-3 zeta Afcs-Nature Molecule Pages. DOI: 10.1038/Mp.A000060.01  0.622
2011 Smith SM, Min J, Ganesh T, Kawahara T, Diebold B, Zhu Y, McCoy J, Sun A, Snyder JP, Fu H, Du Y, Lewis I, Lambeth JD. Ebselen Congeners Inhibit NADPH-oxidase 2 (Nox2)Dependent Superoxide Generation by Interrupting the Binding of Regulatory Subunits Free Radical Biology and Medicine. 51: S98. DOI: 10.1016/J.Freeradbiomed.2011.10.472  0.314
2010 Qiu X, Du Y, Lou B, Zuo Y, Shao W, Huo Y, Huang J, Yu Y, Zhou B, Du J, Fu H, Bu X. Synthesis and identification of new 4-arylidene curcumin analogues as potential anticancer agents targeting nuclear factor-κB signaling pathway. Journal of Medicinal Chemistry. 53: 8260-73. PMID 21070043 DOI: 10.1021/Jm1004545  0.364
2010 Xu Z, Fulop Z, Wu G, Pone EJ, Zhang J, Mai T, Thomas LM, Al-Qahtani A, White CA, Park SR, Steinacker P, Li Z, Yates J, Herron B, Otto M, ... ... Fu H, et al. 14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination. Nature Structural & Molecular Biology. 17: 1124-35. PMID 20729863 DOI: 10.1038/Nsmb.1884  0.347
2010 Thomas SL, Zhao J, Li Z, Lou B, Du Y, Purcell J, Snyder JP, Khuri FR, Liotta D, Fu H. Activation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy. Biochemical Pharmacology. 80: 1309-16. PMID 20615389 DOI: 10.1016/J.Bcp.2010.06.048  0.626
2010 Ramalingam SS, Harvey RD, Saba N, Owonikoko TK, Kauh J, Shin DM, Sun SY, Strychor S, Tighiouart M, Egorin MJ, Fu H, Khuri FR. Phase 1 and pharmacokinetic study of everolimus, a mammalian target of rapamycin inhibitor, in combination with docetaxel for recurrent/refractory nonsmall cell lung cancer. Cancer. 116: 3903-9. PMID 20564143 DOI: 10.1002/Cncr.25264  0.302
2010 Cockrell LM, Puckett MC, Goldman EH, Khuri FR, Fu H. Dual engagement of 14-3-3 proteins controls signal relay from ASK2 to the ASK1 signalosome. Oncogene. 29: 822-30. PMID 19935702 DOI: 10.1038/Onc.2009.382  0.814
2010 Puckett MC, Goldman E, Cockrell L, Khuri F, Fu H. Abstract 1201: Inhibition of ASK1 through phosphorylation of serine 967 by PI3K/Akt-mediated pathways Cancer Research. 70: 1201-1201. DOI: 10.1158/1538-7445.Am10-1201  0.817
2009 Titus MA, Tan JA, Gregory CW, Ford OH, Subramanian RR, Fu H, Wilson EM, Mohler JL, French FS. 14-3-3{eta} Amplifies Androgen Receptor Actions in Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 7571-7581. PMID 19996220 DOI: 10.1158/1078-0432.Ccr-08-1976  0.63
2009 Wang R, He H, Sun X, Xu J, Marshall FF, Zhau H, Chung LW, Fu H, He D. Transcription variants of the prostate-specific PrLZ gene and their interaction with 14-3-3 proteins. Biochemical and Biophysical Research Communications. 389: 455-60. PMID 19732746 DOI: 10.1016/J.Bbrc.2009.08.165  0.331
2009 Du Y, Li Z, Li L, Chen ZG, Sun SY, Chen P, Shin DM, Khuri FR, Fu H. Distinct growth factor-induced dynamic mass redistribution (DMR) profiles for monitoring oncogenic signaling pathways in various cancer cells. Journal of Receptor and Signal Transduction Research. 29: 182-94. PMID 19604037 DOI: 10.1080/10799890902976933  0.406
2009 Jang SW, Liu X, Fu H, Rees H, Yepes M, Levey A, Ye K. Interaction of Akt-phosphorylated SRPK2 with 14-3-3 mediates cell cycle and cell death in neurons. The Journal of Biological Chemistry. 284: 24512-25. PMID 19592491 DOI: 10.1074/Jbc.M109.026237  0.396
2009 Aslan JE, You H, Williamson DM, Endig J, Youker RT, Thomas L, Shu H, Du Y, Milewski RL, Brush MH, Possemato A, Sprott K, Fu H, Greis KD, Runckel DN, et al. Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis. Molecular Cell. 34: 497-509. PMID 19481529 DOI: 10.1016/J.Molcel.2009.04.011  0.429
2009 Bialkowska AB, Du Y, Fu H, Yang VW. Identification of novel small-molecule compounds that inhibit the proproliferative Kruppel-like factor 5 in colorectal cancer cells by high-throughput screening. Molecular Cancer Therapeutics. 8: 563-70. PMID 19240162 DOI: 10.1158/1535-7163.Mct-08-0767  0.334
2009 Gunther JR, Du Y, Rhoden E, Lewis I, Revennaugh B, Moore TW, Kim SH, Dingledine R, Fu H, Katzenellenbogen JA. A set of time-resolved fluorescence resonance energy transfer assays for the discovery of inhibitors of estrogen receptor-coactivator binding. Journal of Biomolecular Screening. 14: 181-93. PMID 19196699 DOI: 10.1177/1087057108329349  0.318
2009 Song X, Coffa S, Fu H, Gurevich VV. How does arrestin assemble MAPKs into a signaling complex? The Journal of Biological Chemistry. 284: 685-95. PMID 19001375 DOI: 10.1074/Jbc.M806124200  0.398
2009 Ramachandiran S, Adone A, Guo X, Liao A, Sunay UR, Ratner L, Fu H, Lossos IS, Saavedra H, Bernal-Mizrachi L. Genomic Stability: A Novel Function of NF-Kb in Lymphomas. Blood. 114: 3240-3240. DOI: 10.1182/Blood.V114.22.3240.3240  0.331
2008 Du Y, Khuri FR, Fu H. A homogenous luminescent proximity assay for 14-3-3 interactions with both phosphorylated and nonphosphorylated client peptides. Current Chemical Genomics. 2: 40-7. PMID 20161842 DOI: 10.2174/1875397300802010040  0.442
2008 Wang X, Hawk N, Yue P, Kauh J, Ramalingam SS, Fu H, Khuri FR, Sun SY. Overcoming mTOR inhibition-induced paradoxical activation of survival signaling pathways enhances mTOR inhibitors' anticancer efficacy. Cancer Biology & Therapy. 7: 1952-8. PMID 18981735 DOI: 10.4161/Cbt.7.12.6944  0.425
2008 Wang X, Yue P, Kim YA, Fu H, Khuri FR, Sun SY. Enhancing mammalian target of rapamycin (mTOR)-targeted cancer therapy by preventing mTOR/raptor inhibition-initiated, mTOR/rictor-independent Akt activation. Cancer Research. 68: 7409-18. PMID 18794129 DOI: 10.1158/0008-5472.Can-08-1522  0.407
2008 Ganesh T, Thepchatri P, Li L, Du Y, Fu H, Snyder JP, Sun A. Synthesis and SAR study of N-(4-hydroxy-3-(2-hydroxynaphthalene-1-yl)phenyl)-arylsulfonamides: heat shock protein 90 (Hsp90) inhibitors with submicromolar activity in an in vitro assay. Bioorganic & Medicinal Chemistry Letters. 18: 4982-7. PMID 18762423 DOI: 10.1016/J.Bmcl.2008.08.022  0.328
2008 Kasinski AL, Du Y, Thomas SL, Zhao J, Sun SY, Khuri FR, Wang CY, Shoji M, Sun A, Snyder JP, Liotta D, Fu H. Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin. Molecular Pharmacology. 74: 654-61. PMID 18577686 DOI: 10.1124/Mol.108.046201  0.766
2008 Ganesh T, Min J, Thepchatri P, Du Y, Li L, Lewis I, Wilson L, Fu H, Chiosis G, Dingledine R, Liotta D, Snyder JP, Sun A. Discovery of aminoquinolines as a new class of potent inhibitors of heat shock protein 90 (Hsp90): Synthesis, biology, and molecular modeling. Bioorganic & Medicinal Chemistry. 16: 6903-10. PMID 18571929 DOI: 10.1016/J.Bmc.2008.05.047  0.333
2008 Min W, Lin Y, Tang S, Yu L, Zhang H, Wan T, Luhn T, Fu H, Chen H. AIP1 recruits phosphatase PP2A to ASK1 in tumor necrosis factor-induced ASK1-JNK activation. Circulation Research. 102: 840-8. PMID 18292600 DOI: 10.1161/CIRCRESAHA.107.168153  0.371
2008 Li Z, Zhao J, Du Y, Park HR, Sun SY, Bernal-Mizrachi L, Aitken A, Khuri FR, Fu H. Down-regulation of 14-3-3zeta suppresses anchorage-independent growth of lung cancer cells through anoikis activation. Proceedings of the National Academy of Sciences of the United States of America. 105: 162-7. PMID 18162532 DOI: 10.1073/Pnas.0710905105  0.353
2008 Park HR, Cockrell LM, Du Y, Kasinski A, Havel J, Zhao J, Reyes-Turcu F, Wilkinson KD, Fu H. Protein-protein interactions Molecular Biomethods Handbook: Second Edition. 463-494. DOI: 10.1007/978-1-60327-375-6_30  0.82
2007 Du Y, Moulick K, Rodina A, Aguirre J, Felts S, Dingledine R, Fu H, Chiosis G. High-throughput screening fluorescence polarization assay for tumor-specific Hsp90. Journal of Biomolecular Screening. 12: 915-24. PMID 17942784 DOI: 10.1177/1087057107306067  0.345
2007 Wang X, Yue P, Chan CB, Ye K, Ueda T, Watanabe-Fukunaga R, Fukunaga R, Fu H, Khuri FR, Sun SY. Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation. Molecular and Cellular Biology. 27: 7405-13. PMID 17724079 DOI: 10.1128/MCB.00760-07  0.367
2007 Dong S, Kang S, Gu TL, Kardar S, Fu H, Lonial S, Khoury HJ, Khuri F, Chen J. 14-3-3 Integrates prosurvival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1-transformed hematopoietic cells. Blood. 110: 360-9. PMID 17389761 DOI: 10.1182/Blood-2006-12-065615  0.445
2007 Luhn P, Wang H, Marcus AI, Fu H. Identification of FAKTS as a novel 14-3-3-associated nuclear protein. Proteins. 67: 479-89. PMID 17256767 DOI: 10.1002/Prot.21288  0.808
2007 Rong J, Li S, Sheng G, Wu M, Coblitz B, Li M, Fu H, Li XJ. 14-3-3 protein interacts with Huntingtin-associated protein 1 and regulates its trafficking. The Journal of Biological Chemistry. 282: 4748-56. PMID 17166838 DOI: 10.1074/Jbc.M609057200  0.444
2006 Sun SY, Fu H, Khuri FR. Targeting mTOR signaling for lung cancer therapy. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 1: 109-11. PMID 17409838 DOI: 10.1016/S1556-0864(15)31524-0  0.463
2006 Pozdeyev N, Taylor C, Haque R, Chaurasia SS, Visser A, Thazyeen A, Du Y, Fu H, Weller J, Klein DC, Iuvone PM. Photic regulation of arylalkylamine N-acetyltransferase binding to 14-3-3 proteins in retinal photoreceptor cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9153-61. PMID 16957072 DOI: 10.1523/Jneurosci.1384-06.2006  0.428
2006 Du Y, Masters SC, Khuri FR, Fu H. Monitoring 14-3-3 protein interactions with a homogeneous fluorescence polarization assay. Journal of Biomolecular Screening. 11: 269-76. PMID 16699128 DOI: 10.1177/1087057105284862  0.756
2006 Porter GW, Khuri FR, Fu H. Dynamic 14-3-3/client protein interactions integrate survival and apoptotic pathways. Seminars in Cancer Biology. 16: 193-202. PMID 16697216 DOI: 10.1016/J.Semcancer.2006.03.003  0.81
2006 Wu M, Coblitz B, Shikano S, Long S, Cockrell LM, Fu H, Li M. SWTY--a general peptide probe for homogeneous solution binding assay of 14-3-3 proteins. Analytical Biochemistry. 349: 186-96. PMID 16403428 DOI: 10.1016/J.Ab.2005.11.030  0.797
2006 Dong S, Kang S, Gu T, Kardar S, Lonial S, Khoury HJ, Khuri F, Fu H, Chen J. 14-3-3 Integrates Pro-Survival Signals in Hematopoietic Cells Transformed by Diverse Leukemogenic Tyrosine Kinases, and Represents a Common Target. Blood. 108: 1138-1138. DOI: 10.1182/Blood.V108.11.1138.1138  0.463
2005 Hu Y, Yao J, Liu Z, Liu X, Fu H, Ye K. Akt phosphorylates acinus and inhibits its proteolytic cleavage, preventing chromatin condensation. The Embo Journal. 24: 3543-54. PMID 16177823 DOI: 10.1038/Sj.Emboj.7600823  0.414
2005 Coblitz B, Shikano S, Wu M, Gabelli SB, Cockrell LM, Spieker M, Hanyu Y, Fu H, Amzel LM, Li M. C-terminal recognition by 14-3-3 proteins for surface expression of membrane receptors. The Journal of Biological Chemistry. 280: 36263-72. PMID 16123035 DOI: 10.1074/Jbc.M507559200  0.792
2005 Sun SY, Rosenberg LM, Wang X, Zhou Z, Yue P, Fu H, Khuri FR. Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition. Cancer Research. 65: 7052-8. PMID 16103051 DOI: 10.1158/0008-5472.Can-05-0917  0.441
2004 Sun SY, Zhou Z, Wang R, Fu H, Khuri FR. The farnesyltransferase inhibitor Lonafarnib induces growth arrest or apoptosis of human lung cancer cells without downregulation of Akt. Cancer Biology & Therapy. 3: 1092-8; discussion 1. PMID 15467440 DOI: 10.4161/Cbt.3.11.1176  0.349
2004 Ku NO, Fu H, Omary MB. Raf-1 activation disrupts its binding to keratins during cell stress. The Journal of Cell Biology. 166: 479-85. PMID 15314064 DOI: 10.1083/Jcb.200402051  0.407
2004 Fujii K, Goldman EH, Park HR, Zhang L, Chen J, Fu H. Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034. Oncogene. 23: 5099-104. PMID 15094778 DOI: 10.1038/Sj.Onc.1207668  0.81
2004 Chen J, Williams IR, Kutok JL, Duclos N, Anastasiadou E, Masters SC, Fu H, Gilliland DG. Positive and negative regulatory roles of the WW-like domain in TEL-PDGFbetaR transformation. Blood. 104: 535-42. PMID 15054045 DOI: 10.1182/Blood-2004-01-0169  0.747
2004 Subramanian RR, Zhang H, Wang H, Ichijo H, Miyashita T, Fu H. Interaction of apoptosis signal-regulating kinase 1 with isoforms of 14-3-3 proteins. Experimental Cell Research. 294: 581-91. PMID 15023544 DOI: 10.1016/J.Yexcr.2003.12.009  0.751
2004 Goldman EH, Chen L, Fu H. Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation. The Journal of Biological Chemistry. 279: 10442-9. PMID 14688258 DOI: 10.1074/Jbc.M311129200  0.782
2004 Titus MA, Gregory CW, Smitherman AB, Subramanian RR, Fu H, Mohler JL, French FS. 582: 14-3-3η Protein Mediates AR Transactivation in Recurrent Prostate Cancer The Journal of Urology. 171: 154-155. DOI: 10.1016/S0022-5347(18)37844-3  0.643
2003 Hamaguchi A, Suzuki E, Murayama K, Fujimura T, Hikita T, Iwabuchi K, Handa K, Withers DA, Masters SC, Fu H, Hakomori S. A sphingosine-dependent protein kinase that specifically phosphorylates 14-3-3 (SDK1) is identified as the kinase domain of PKCδ: A preliminary note Biochemical and Biophysical Research Communications. 307: 589-594. PMID 12893264 DOI: 10.1016/S0006-291X(03)01070-2  0.758
2003 Hamaguchi A, Suzuki E, Murayama K, Fujimura T, Hikita T, Iwabuchi K, Handa K, Withers DA, Masters SC, Fu H, Hakomori S. Sphingosine-dependent Protein Kinase-1, Directed to 14-3-3, Is Identified as the Kinase Domain of Protein Kinase Cδ Journal of Biological Chemistry. 278: 41557-41565. PMID 12855683 DOI: 10.1074/Jbc.M305294200  0.771
2002 Truong AB, Masters SC, Yang H, Fu H. Role of the 14-3-3 C-terminal loop in ligand interaction. Proteins. 49: 321-5. PMID 12360521 DOI: 10.1002/Prot.10210  0.78
2002 Masters SC, Subramanian RR, Truong A, Yang H, Fujii K, Zhang H, Fu H. Survival-promoting functions of 14-3-3 proteins. Biochemical Society Transactions. 30: 360-5. PMID 12196095 DOI: 10.1042/Bst0300360  0.823
2002 Masters SC, Subramanian RR, Truong A, Yang H, Fujii K, Zhang H, Fu H. Prosurvival Function of 14-3-3 Proteins Biochemical Society Transactions. 30: A62-A62. DOI: 10.1042/Bst030A062A  0.785
2001 Masters SC, Yang H, Datta SR, Greenberg ME, Fu H. 14-3-3 inhibits Bad-induced cell death through interaction with serine-136. Molecular Pharmacology. 60: 1325-31. PMID 11723239 DOI: 10.1124/Mol.60.6.1325  0.776
2001 Subramanian RR, Masters SC, Zhang H, Fu H. Functional conservation of 14-3-3 isoforms in inhibiting bad-induced apoptosis. Experimental Cell Research. 271: 142-51. PMID 11697890 DOI: 10.1006/Excr.2001.5376  0.816
2001 Masters SC, Fu H. 14-3-3 proteins mediate an essential anti-apoptotic signal. The Journal of Biological Chemistry. 276: 45193-200. PMID 11577088 DOI: 10.1074/Jbc.M105971200  0.791
2001 Chen J, Fujii K, Zhang L, Roberts T, Fu H. Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 98: 7783-7788. PMID 11427728 DOI: 10.1073/Pnas.141224398  0.52
2001 Yang H, Masters SC, Wang H, Fu H. The proapoptotic protein Bad binds the amphipathic groove of 14-3-3zeta. Biochimica Et Biophysica Acta. 1547: 313-9. PMID 11410287 DOI: 10.1016/S0167-4838(01)00202-3  0.796
2000 Athwal GS, Lombardo CR, Huber JL, Masters SC, Fu H, Huber SC. Modulation of 14-3-3 protein interactions with target polypeptides by physical and metabolic effectors. Plant & Cell Physiology. 41: 523-33. PMID 10845467 DOI: 10.1093/Pcp/41.4.523  0.742
2000 Fu H, Subramanian RR, Masters SC. 14-3-3 proteins: structure, function, and regulation. Annual Review of Pharmacology and Toxicology. 40: 617-47. PMID 10836149 DOI: 10.1146/Annurev.Pharmtox.40.1.617  0.831
1999 Zhang L, Wang H, Masters SC, Wang B, Barbieri JT, Fu H. Residues of 14-3-3 zeta required for activation of exoenzyme S of Pseudomonas aeruginosa. Biochemistry. 38: 12159-64. PMID 10508420 DOI: 10.1021/Bi991019L  0.747
1999 Wang B, Yang H, Liu YC, Jelinek T, Zhang L, Ruoslahti E, Fu H. Isolation of high-affinity peptide antagonists of 14-3-3 proteins by phage display. Biochemistry. 38: 12499-504. PMID 10493820 DOI: 10.1021/Bi991353H  0.396
1999 Zhang L, Chen J, Fu H. Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins. Proceedings of the National Academy of Sciences of the United States of America. 96: 8511-8515. PMID 10411906 DOI: 10.1073/Pnas.96.15.8511  0.482
1999 Masters SC, Pederson KJ, Zhang L, Barbieri JT, Fu H. Interaction of 14-3-3 with a nonphosphorylated protein ligand, exoenzyme S of Pseudomonas aeruginosa. Biochemistry. 38: 5216-21. PMID 10213629 DOI: 10.1021/Bi982492M  0.761
1998 Petosa C, Masters SC, Bankston LA, Pohl J, Wang B, Fu H, Liddington RC. 14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove. The Journal of Biological Chemistry. 273: 16305-10. PMID 9632691 DOI: 10.1074/jbc.273.26.16305  0.721
1998 Wang H, Zhang L, Liddington R, Fu H. Mutations in the hydrophobic surface of an amphipathic groove of 14-3-3zeta disrupt its interaction with Raf-1 kinase. The Journal of Biological Chemistry. 273: 16297-304. PMID 9632690 DOI: 10.1074/Jbc.273.26.16297  0.394
1997 Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell. 91: 231-41. PMID 9346240 DOI: 10.1016/S0092-8674(00)80405-5  0.767
1997 Zhang L, Wang H, Liu D, Liddington R, Fu H. Raf-1 kinase and exoenzyme S interact with 14-3-3zeta through a common site involving lysine 49. The Journal of Biological Chemistry. 272: 13717-24. PMID 9153224 DOI: 10.1074/Jbc.272.21.13717  0.41
1996 Van Nocker S, Sadis S, Rubin DM, Glickman M, Fu H, Coux O, Wefes I, Finley D, Vierstra RD. The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate- specific role in protein turnover Molecular and Cellular Biology. 16: 6020-6028. PMID 8887631 DOI: 10.1128/Mcb.16.11.6020  0.385
1995 Liu D, Bienkowska J, Petosa C, Collier RJ, Fu H, Liddington R. Crystal structure of the zeta isoform of the 14-3-3 protein. Nature. 376: 191-4. PMID 7603574 DOI: 10.1038/376191A0  0.448
1994 Pallas DC, Fu H, Haehnel LC, Weller W, Collier RJ, Roberts TM. Association of polyomavirus middle tumor antigen with 14-3-3 proteins. Science (New York, N.Y.). 265: 535-7. PMID 8036498 DOI: 10.1126/Science.8036498  0.428
1994 Reuther GW, Fu H, Cripe LD, Collier RJ, Pendergast AM. Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family. Science (New York, N.Y.). 266: 129-33. PMID 7939633 DOI: 10.1126/Science.7939633  0.494
1994 Fu H, Xia K, Pallas DC, Cui C, Conroy K, Narsimhan RP, Mamon H, Collier RJ, Roberts TM. Interaction of the protein kinase Raf-1 with 14-3-3 proteins. Science (New York, N.Y.). 266: 126-9. PMID 7939632 DOI: 10.1126/Science.7939632  0.455
1993 Fu H, Coburn J, Collier RJ. The eukaryotic host factor that activates exoenzyme S of Pseudomonas aeruginosa is a member of the 14-3-3 protein family. Proceedings of the National Academy of Sciences of the United States of America. 90: 2320-4. PMID 8460141 DOI: 10.1073/Pnas.90.6.2320  0.424
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