| Year |
Citation |
Score |
| 2014 |
Beerman TA, Gawron LS, Shen B, Kennedy DR. The radiomimetic enediyne, 20'-deschloro-C-1027 induces inter-strand DNA crosslinks in hypoxic cells and overcomes cytotoxic radioresistance. Dna Repair. 21: 165-70. PMID 24986640 DOI: 10.1016/J.Dnarep.2014.06.001 |
0.643 |
|
| 2012 |
San Pedro JM, Beerman TA, Greenberg MM. DNA damage by C1027 involves hydrogen atom abstraction and addition to nucleobases. Bioorganic & Medicinal Chemistry. 20: 4744-50. PMID 22748380 DOI: 10.1016/J.Bmc.2012.06.004 |
0.594 |
|
| 2009 |
McHugh MM, Beerman TA. An extraction-free method by which a single slot blot can be used to quantify intracellular DNA damage (crosslinks or strand breaks) and changes in DNA damage response proteins or replication Biotechniques. 46: 127-129. PMID 19317657 DOI: 10.2144/000113046 |
0.545 |
|
| 2009 |
Beerman TA, Gawron LS, Shin S, Shen B, McHugh MM. C-1027, a radiomimetic enediyne anticancer drug, preferentially targets hypoxic cells. Cancer Research. 69: 593-8. PMID 19147573 DOI: 10.1158/0008-5472.Can-08-2753 |
0.558 |
|
| 2007 |
Kennedy DR, Ju J, Shen B, Beerman TA. Designer enediynes generate DNA breaks, interstrand cross-links, or both, with concomitant changes in the regulation of DNA damage responses. Proceedings of the National Academy of Sciences of the United States of America. 104: 17632-7. PMID 17978180 DOI: 10.1073/Pnas.0708274104 |
0.599 |
|
| 2007 |
Kennedy DR, Gawron LS, Ju J, Liu W, Shen B, Beerman TA. Single chemical modifications of the C-1027 enediyne core, a radiomimetic antitumor drug, affect both drug potency and the role of ataxia-telangiectasia mutated in cellular responses to DNA double-strand breaks. Cancer Research. 67: 773-81. PMID 17234789 DOI: 10.1158/0008-5472.Can-06-2893 |
0.66 |
|
| 2006 |
Dziegielewska B, Beerman TA, Bianco PR. Inhibition of RecBCD enzyme by antineoplastic DNA alkylating agents. Journal of Molecular Biology. 361: 898-919. PMID 16887143 DOI: 10.1016/J.Jmb.2006.06.068 |
0.758 |
|
| 2006 |
Knights CD, Catania J, Di Giovanni S, Muratoglu S, Perez R, Swartzbeck A, Quong AA, Zhang X, Beerman T, Pestell RG, Avantaggiati ML. Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate. The Journal of Cell Biology. 173: 533-44. PMID 16717128 DOI: 10.1083/Jcb.200512059 |
0.366 |
|
| 2006 |
Kennedy DR, Beerman TA. The radiomimetic enediyne C-1027 induces unusual DNA damage responses to double-strand breaks. Biochemistry. 45: 3747-54. PMID 16533058 DOI: 10.1021/bi052334c |
0.5 |
|
| 2005 |
Tu LC, Matsui SI, Beerman TA. Hedamycin, a DNA alkylator, induces (gamma)H2AX and chromosome aberrations: involvement of phosphatidylinositol 3-kinase-related kinases and DNA replication fork movement. Molecular Cancer Therapeutics. 4: 1175-85. PMID 16093433 DOI: 10.1158/1535-7163.Mct-05-0054 |
0.654 |
|
| 2005 |
Wu J, Ling X, Pan D, Apontes P, Song L, Liang P, Altieri DC, Beerman T, Li F. Molecular mechanism of inhibition of survivin transcription by the GC-rich sequence-selective DNA binding antitumor agent, hedamycin: evidence of survivin down-regulation associated with drug sensitivity. The Journal of Biological Chemistry. 280: 9745-51. PMID 15637054 DOI: 10.1074/Jbc.M409350200 |
0.555 |
|
| 2005 |
Philips BJ, Chang AY, Dervan PB, Beerman TA. DNA damage effects of a polyamide-CBI conjugate in SV40 virions. Molecular Pharmacology. 67: 877-82. PMID 15576630 DOI: 10.1124/Mol.104.006254 |
0.699 |
|
| 2004 |
Dziegielewska B, Kowalski D, Beerman TA. SV40 DNA replication inhibition by the monofunctional DNA alkylator Et743. Biochemistry. 43: 14228-37. PMID 15518573 DOI: 10.1021/Bi049407X |
0.765 |
|
| 2004 |
Tu LC, Melendy T, Beerman TA. DNA damage responses triggered by a highly cytotoxic monofunctional DNA alkylator, hedamycin, a pluramycin antitumor antibiotic. Molecular Cancer Therapeutics. 3: 577-85. PMID 15141015 |
0.455 |
|
| 2004 |
Cao PR, McHugh MM, Melendy T, Beerman T. The DNA minor groove-alkylating cyclopropylpyrroloindole drugs adozelesin and bizelesin induce different DNA damage response pathways in human colon carcinoma HCT116 cells. Molecular Cancer Therapeutics. 2: 651-9. PMID 12883038 |
0.49 |
|
| 2003 |
Wang YD, Dziegielewski J, Wurtz NR, Dziegielewska B, Dervan PB, Beerman TA. DNA crosslinking and biological activity of a hairpin polyamide-chlorambucil conjugate. Nucleic Acids Research. 31: 1208-15. PMID 12582240 DOI: 10.1093/Nar/Gkg215 |
0.763 |
|
| 2003 |
Liu JS, Kuo SR, Beerman TA, Melendy T. Induction of DNA damage responses by adozelesin is S phase-specific and dependent on active replication forks Molecular Cancer Therapeutics. 2: 41-47. PMID 12533671 |
0.601 |
|
| 2002 |
Wang YD, Dziegielewski J, Chang AY, Dervan PB, Beerman TA. Cell-free and cellular activities of a DNA sequence selective hairpin polyamide-CBI conjugate. The Journal of Biological Chemistry. 277: 42431-7. PMID 12196541 DOI: 10.1074/Jbc.M207179200 |
0.718 |
|
| 2002 |
Belitsky JM, Leslie SJ, Arora PS, Beerman TA, Dervan PB. Cellular uptake of N-methylpyrrole/N-methylimidazole polyamide-dye conjugates. Bioorganic & Medicinal Chemistry. 10: 3313-8. PMID 12150878 DOI: 10.1016/S0968-0896(02)00204-3 |
0.648 |
|
| 2002 |
White CM, Satz AL, Gawron LS, Bruice TC, Beerman TA. Inhibiting transcription factor/DNA complexes using fluorescent microgonotropens (FMGTs). Biochimica Et Biophysica Acta. 1574: 100-8. PMID 11955618 DOI: 10.1016/S0167-4781(01)00351-7 |
0.669 |
|
| 2002 |
Dziegielewski J, Beerman TA. Cellular responses to the DNA strand-scission enediyne C-1027 can be independent of ATM, ATR, and DNA-PK kinases. The Journal of Biological Chemistry. 277: 20549-54. PMID 11927575 DOI: 10.1074/Jbc.M109897200 |
0.639 |
|
| 2001 |
Liu JS, Kuo SR, Yin X, Beerman TA, Melendy T. DNA damage by the enediyne C-1027 results in the inhibition of DNA replication by loss of replication protein A function and activation of DNA-dependent protein kinase Biochemistry. 40: 14661-14668. PMID 11724580 DOI: 10.1021/Bi015680C |
0.611 |
|
| 2001 |
White CM, Satz AL, Bruice TC, Beerman TA. Inhibition of transcription factor-DNA complexes and gene expression by a microgonotropen. Proceedings of the National Academy of Sciences of the United States of America. 98: 10590-5. PMID 11535831 DOI: 10.1073/Pnas.191374698 |
0.672 |
|
| 2001 |
Satz AL, White CM, Beerman TA, Bruice TC. Double-stranded DNA binding characteristics and subcellular distribution of a minor groove binding diphenyl ether bisbenzimidazole. Biochemistry. 40: 6465-74. PMID 11371210 DOI: 10.1021/Bi0103415 |
0.56 |
|
| 2001 |
Wang Y, Beerman TA, Kowalski D. Antitumor drug adozelesin differentially affects active and silent origins of DNA replication in yeast checkpoint kinase mutants Cancer Research. 61: 3787-3794. PMID 11325853 |
0.486 |
|
| 2001 |
McHugh MM, Yin X, Kuo SR, Liu JS, Melendy T, Beerman TA. The cellular response to DNA damage induced by the enediynes C-1027 and neocarzinostatin includes hyperphosphorylation and increased nuclear retention of replication protein A (RPA) and trans inhibition of DNA replication Biochemistry. 40: 4792-4799. PMID 11294647 DOI: 10.1021/bi001668t |
0.646 |
|
| 2001 |
Dziegielewski J, Melendy T, Beerman TA. Bleomycin-induced alterations in DNA replication: relationship to DNA damage. Biochemistry. 40: 704-11. PMID 11170387 DOI: 10.1021/Bi002181N |
0.699 |
|
| 2000 |
White CM, Heidenreich O, Nordheim A, Beerman TA. Evaluation of the effectiveness of DNA-binding drugs to inhibit transcription using the c-fos serum response element as a target. Biochemistry. 39: 12262-73. PMID 11015205 DOI: 10.1021/Bi001427L |
0.613 |
|
| 2000 |
Chiang SY, Burli RW, Benz CC, Gawron L, Scott GK, Dervan PB, Beerman TA. Targeting the ets binding site of the HER2/neu promoter with pyrrole-imidazole polyamides. The Journal of Biological Chemistry. 275: 24246-54. PMID 10818092 DOI: 10.1074/Jbc.M000820200 |
0.581 |
|
| 2000 |
Liu JS, Kuo SR, McHugh MM, Beerman TA, Melendy T. Adozelesin triggers DNA damage response pathways and arrests SV40 DNA replication through replication protein A inactivation Journal of Biological Chemistry. 275: 1391-1397. PMID 10625690 DOI: 10.1074/Jbc.275.2.1391 |
0.695 |
|
| 1999 |
McHugh MM, Kuo SR, Walsh-O'Beirne MH, Liu JS, Melendy T, Beerman TA. Bizelesin, a bifunctional cyclopropylpyrroloindole alkylating agent, inhibits simian virus 40 replication in trans by induction of an inhibitor Biochemistry. 38: 11508-11515. PMID 10471303 DOI: 10.1021/Bi990598R |
0.673 |
|
| 1999 |
McHugh MM, Beerman TA. C-1027-induced alterations in Epstein-Barr viral DNA replication in latently infected cultured human Raji cells: Relationship to DNA damage Biochemistry. 38: 6962-6970. PMID 10346918 DOI: 10.1021/bi9903143 |
0.585 |
|
| 1999 |
McHugh MM, Beerman TA. Purification of large quantities of high-molecular-weight Epstein-Barr viral and cellular genomic DNA from cultured human Raji cells Biotechniques. 26: 188-194. PMID 10023522 DOI: 10.2144/99262Bm02 |
0.466 |
|
| 1998 |
Chiang SY, Azizkhan JC, Beerman TA. A comparison DNA-binding drug as inhibitors of E2F1- and Sp1-DNA complexes and associated gene expression Biochemistry. 37: 3109-3115. PMID 9485464 DOI: 10.1021/bi9721142 |
0.515 |
|
| 1997 |
Woynarowski JM, Beerman TA. Effects of bizelesin (U-77,779), a bifunctional alkylating minor groove binder, on replication of genomic and simian virus 40 DNA in BSC-1 cells Biochimica Et Biophysica Acta - Gene Structure and Expression. 1353: 50-60. PMID 9256064 DOI: 10.1016/S0167-4781(97)00046-8 |
0.648 |
|
| 1997 |
Tatarowicz WA, Martin CE, Pekosz AS, Madden SL, Rauscher FJ, Chiang SY, Beerman TA, Fraser NW. Repression of the HSV-1 latency-associated transcript (LAT) promoter by the early growth response (EGR) proteins: involvement of a binding site immediately downstream of the TATA box. Journal of Neurovirology. 3: 212-24. PMID 9200069 DOI: 10.3109/13550289709018296 |
0.33 |
|
| 1997 |
Bruice TC, Sengupta D, Blaskó A, Chiang SY, Beerman TA. A microgonotropen branched decaaza decabutylamine and its DNA and DNA/transcription factor interactions. Bioorganic & Medicinal Chemistry. 5: 685-92. PMID 9158867 DOI: 10.1016/S0968-0896(97)00011-4 |
0.653 |
|
| 1997 |
Kirk CA, Goodisman J, Beerman TA, Gawron LS, Dabrowiak JC. Kinetics of cleavage of intra- and extracellular simian virus 40 DNA with the enediyne anticancer drug C-1027. Biophysical Chemistry. 63: 201-9. PMID 9108692 DOI: 10.1016/S0301-4622(96)02217-X |
0.606 |
|
| 1997 |
Chiang SY, Bruice TC, Azizkhan JC, Gawron L, Beerman TA. Targeting E2F1-DNA complexes with microgonotropen DNA binding agents. Proceedings of the National Academy of Sciences of the United States of America. 94: 2811-6. PMID 9096302 DOI: 10.1073/Pnas.94.7.2811 |
0.67 |
|
| 1997 |
McHugh MM, Beerman TA, Burhans WC. DNA-damaging enediyne C-1027 inhibits initiation of intracellular SV40 DNA replication in trans Biochemistry. 36: 1003-1009. PMID 9033389 DOI: 10.1021/Bi962121A |
0.574 |
|
| 1996 |
Chiangt SY, Welch JJ, Rauscher FJ, Beerman TA. Effect of DNA-binding drugs on early growth response factor-1 and TATA box-binding protein complex formation with the herpes simplex virus latency promoter Journal of Biological Chemistry. 271: 23999-24004. PMID 8798634 DOI: 10.1074/Jbc.271.39.23999 |
0.576 |
|
| 1996 |
Cobuzzi RJ, Burhanst WC, Beerman TA. Inhibition of initiation of simian virus 40 DNA replication in infected BSC-1 cells by the DNA alkylating drug adozelesin Journal of Biological Chemistry. 271: 19852-19859. PMID 8702695 DOI: 10.1074/Jbc.271.33.19852 |
0.664 |
|
| 1995 |
McHugh MM, Woynarowski JM, Gawron LS, Otani T, Beerman TA. Effects of the DNA-damaging enediyne C-1027 on intracellular SV40 and genomic DNA in green monkey kidney BSC-1 cells Biochemistry. 34: 1805-1814. PMID 7849041 |
0.618 |
|
| 1995 |
Cobuzzi RJ, Kotsopoulos SK, Otani T, Beerman TA. Effects of the enediyne C-1027 on intracellular DNA targets Biochemistry. 34: 583-592. PMID 7819253 |
0.611 |
|
| 1995 |
Woynarowski JM, McHugh MM, Gawron LS, Beerman TA. Effects of bizelesin (U-77779), a bifunctional alkylating minor groove agent, on genomic and simian virus 40 DNA Biochemistry. 34: 13042-13050. PMID 7548063 |
0.627 |
|
| 1994 |
Woynarowski JM, McCarthy K, Reynolds B, Beerman TA, Denny WA. Topoisomerase II mediated DNA lesions induced by acridine-4-carboxamide and 2-(4-pyridyl)quinoline-8-carboxamide. Anti-Cancer Drug Design. 9: 9-24. PMID 8141968 |
0.535 |
|
| 1994 |
McHugh MM, Woynarowski JM, Mitchell MA, Gawron LS, Weiland KL, Beerman TA. CC-1065 bonding to intracellular and purified SV40 DNA: Site specificity and functional effects Biochemistry. 33: 9158-9168. PMID 8049219 |
0.627 |
|
| 1994 |
Welch JJ, Rauscher FJ, Beerman TA. Targeting DNA-binding drugs to sequence-specific transcription factor-DNA complexes. Differential effects of intercalating and minor groove binding drugs Journal of Biological Chemistry. 269: 31051-31058. PMID 7983044 |
0.553 |
|
| 1994 |
Johnson PG, Beerman TA. Damage induced in episomal EBV DNA in Raji cells by antitumor drugs as measured by pulsed field gel electrophoresis Analytical Biochemistry. 220: 103-114. PMID 7526729 DOI: 10.1006/abio.1994.1305 |
0.596 |
|
| 1994 |
Chiang SY, Welch J, Rauscher FJ, Beerman TA. Effects of minor groove binding drugs on the interaction of TATA box binding protein and TFIIA with DNA Biochemistry. 33: 7033-7040. PMID 7516181 DOI: 10.1021/bi00189a003 |
0.589 |
|
| 1992 |
Beerman TA, McHugh MM, Sigmund R, Lown JW, Rao KE, Bathini Y. Effects of analogs of the DNA minor groove binder Hoechst 33258 on topoisomerase II and I mediated activities. Biochimica Et Biophysica Acta. 1131: 53-61. PMID 1374646 DOI: 10.1016/0167-4781(92)90098-K |
0.634 |
|
| 1992 |
Zsido TJ, Beerman TA, Meegan RL, Woynarowski JM, Baker RM. Resistance of CHO cells expressing P-glycoprotein to cyclopropylpyrroloindole (CPI) alkylating agents Biochemical Pharmacology. 43: 1817-1822. PMID 1349478 DOI: 10.1016/0006-2952(92)90715-U |
0.378 |
|
| 1991 |
Ferrazzi E, Woynarowski JM, Arakali A, Brenner DE, Beerman TA. DNA damage and cytotoxicity induced by metabolites of anthracycline antibiotics, doxorubicin and idarubicin. Cancer Communications. 3: 173-80. PMID 2049226 DOI: 10.3727/095535491820873308 |
0.585 |
|
| 1991 |
Vertino PM, Beerman TA, Kelly EJ, Bergeron RJ, Porter CW. Selective cellular depletion of mitochondrial DNA by the polyamine analog N1,N12-bis(ethyl)spermine and its relationship to polyamine structure and function. Molecular Pharmacology. 39: 487-94. PMID 2017149 |
0.55 |
|
| 1991 |
Zsido TJ, Woynarowski JM, Baker RM, Gawron LS, Beerman TA. Induction of heat-labile sites in DNA of mammalian cells by the antitumor alkylating drug CC-1065 Biochemistry. 30: 3733-3738. PMID 1849736 |
0.581 |
|
| 1991 |
Cullinan EB, Gawron LS, Rustum YM, Beerman TA. Extrachromosomal chromatin: Novel target for bleomycin cleavage in cells and solid tumors Biochemistry. 30: 3055-3061. PMID 1706627 |
0.452 |
|
| 1991 |
Beerman TA, Woynarowski JM, Sigmund RD, Gawron LS, Rao KE, Lown JW. Netropsin and bis-netropsin analogs as inhibitors of the catalytic activity of mammalian DNA topoisomerase II and topoisomerase cleavable complexes Bba - Gene Structure and Expression. 1090: 52-60. PMID 1653020 DOI: 10.1016/0167-4781(91)90036-L |
0.539 |
|
| 1990 |
Cullinan EB, Gawron LS, Rustum YM, Beerman TA. Topoisomerase II-mediated DNA Damage of Episomes in Tumor-bearing Mice Cancer Research. 50: 6154-6157. PMID 2169334 |
0.408 |
|
| 1990 |
McHugh MM, Sigmund RD, Beerman TA. Effects of minor groove binding drugs on camptothecin-induced DNA lesions in L1210 nuclei Biochemical Pharmacology. 39: 707-714. PMID 1689578 DOI: 10.1016/0006-2952(90)90149-F |
0.655 |
|
| 1989 |
Van Roey P, Beerman TA. Crystal structure analysis of auromomycin apoprotein (macromomycin) shows importance of protein side chains to chromophore binding selectivity Proceedings of the National Academy of Sciences of the United States of America. 86: 6587-6591. PMID 2771945 DOI: 10.1073/Pnas.86.17.6587 |
0.321 |
|
| 1989 |
Woynarowski JM, McNamee H, Szmigiero L, Beerman TA, Konopa J. Induction of DNA-protein crosslinks by antitumor 1-nitro-9-aminoacridines in L1210 leukemia cells Biochemical Pharmacology. 38: 4095-4101. PMID 2557039 DOI: 10.1016/0006-2952(89)90691-6 |
0.635 |
|
| 1989 |
Cullinan EB, Beerman TA. A study of drug-induced topoisomerase II-mediated DNA lesions on episomal chromatin Journal of Biological Chemistry. 264: 16268-16275. PMID 2550434 |
0.543 |
|
| 1989 |
Woynarowski JM, Sigmund RD, Beerman TA. DNA minor groove binding agents interfere with topoisomerase II mediated lesions induced by epipodophyllotoxin derivative VM-26 and acridine derivative m-AMSA in nuclei from L1210 cells Biochemistry. 28: 3850-3855. PMID 2473776 |
0.643 |
|
| 1989 |
McHugh MM, Woynarowski JM, Sigmund RD, Beerman TA. Effect of minor groove binding drugs on mammalian topoisomerase I activity Biochemical Pharmacology. 38: 2323-2328. PMID 2473754 DOI: 10.1016/0006-2952(89)90472-3 |
0.451 |
|
| 1989 |
Woynarowski JM, McHugh M, Sigmund RD, Beerman TA. Modulation of topoisomerase II catalytic activity by DNA minor groove binding agents distamycin, Hoechst 33258, and 4',6-diamidine-2-phenylindole Molecular Pharmacology. 35: 177-182. PMID 2465485 |
0.579 |
|
| 1989 |
Woynarowski JM, Beerman TA. Preferential effect of bleomycin on newly replicated chromatin in nuclei from L1210 cells Bba - Gene Structure and Expression. 1007: 116-119. PMID 2462448 DOI: 10.1016/0167-4781(89)90139-5 |
0.382 |
|
| 1988 |
Grimwade JE, Cullinan EB, Beerman TA. Neocarzinostatin and auromomycin preferentially cleave simian virus 40 DNA and chromosomes at a number of discrete locations Bba - Gene Structure and Expression. 950: 102-112. PMID 2838085 DOI: 10.1016/0167-4781(88)90002-4 |
0.539 |
|
| 1988 |
Woynarowski JM, Sigmund RD, Beerman TA. Topoisomerase-II-mediated lesions in nascent DNA: Comparison of the effects of epipodophyllotoxin derivatives, VM-26 and VP-16, and 9-anilinoacridine derivatives, m-AMSA and o-AMSA Bba - Gene Structure and Expression. 950: 21-29. PMID 2833925 DOI: 10.1016/0167-4781(88)90069-3 |
0.63 |
|
| 1987 |
Beckmann RP, Agostino MJ, McHugh MM, Sigmund RD, Beerman TA. Assessment of preferential cleavage of an actively transcribed retroviral hybrid gene in murine cells by deoxyribonuclease I, bleomycin, neocarzinostatin, or ionizing radiation Biochemistry. 26: 5409-5415. PMID 2445373 |
0.344 |
|
| 1987 |
Griinwade JE, Cason EB, Beerman TA. Site specificity of bleomycin cleavage in purified and intracellular simian virus 40 DNA Nucleic Acids Research. 15: 6315-6329. PMID 2442726 DOI: 10.1093/nar/15.16.6315 |
0.6 |
|
| 1986 |
Grimwade JE, Beerman TA. Measurement of bleomycin, neocarzinostatin, and auromomycin cleavage of cell-free and intracellular simian virus 40 DNA and chromatin Molecular Pharmacology. 30: 358-363. PMID 2429169 |
0.509 |
|
| 1985 |
Pavelic K, Beerman TA, Bernacki RJ. An evaluation of the effects of combination chemotherapy in vitro using DNA-reactive agents Cancer Drug Delivery. 2: 255-270. PMID 2415231 DOI: 10.1089/Cdd.1985.2.255 |
0.534 |
|
| 1984 |
Agostino MJ, Bernacki RJ, Beerman TA. Synergistic interactions of ethidium bromide and bleomycin on cellular DNA and growth inhibition Biochemical and Biophysical Research Communications. 120: 156-163. PMID 6201171 DOI: 10.1016/0006-291X(84)91427-X |
0.538 |
|
| 1983 |
Grimmond HE, Beerman T. Alteration of chromatin structure induced by the binding of adriamycin, daunorubicin and ethidium bromide. Biochemical Pharmacology. 31: 3379-86. PMID 7150361 DOI: 10.1016/0006-2952(82)90615-3 |
0.429 |
|
| 1983 |
Beerman TA, Mueller G, Grimmond H. Effects of neocarzinostatin on chromatin in HeLa S3 nuclei Molecular Pharmacology. 23: 493-499. PMID 6220204 |
0.39 |
|
| 1982 |
Fiel RJ, Beerman TA, Mark EH, Datta-Gupta N. DNA strand scission activity of metalloporphyrins Biochemical and Biophysical Research Communications. 107: 1067-1074. PMID 7138512 DOI: 10.1016/0006-291X(82)90630-1 |
0.307 |
|
| 1982 |
McHugh MM, Woynarowski J, Beerman T. Degradation of HeLa cell chromatin by neocarzinostatin and its chromophore. Biochimica Et Biophysica Acta. 696: 7-14. PMID 6211192 DOI: 10.1016/0167-4781(82)90003-3 |
0.398 |
|
| 1981 |
Van Roey P, Weeks CM, DeJarnette FE, Beerman TA, McHugh M. Preliminary crystallographic study of macromomycin. The apoprotein of the antitumor antibiotic auromomycin Journal of Molecular Biology. 153: 183-185. PMID 7338912 DOI: 10.1016/0022-2836(81)90534-9 |
0.402 |
|
| 1980 |
Woynarowski JM, Beerman TA. Inhibition of DNA replication in HeLa S3 cells by macromomycin-I, an antitumor protein antibiotic Molecular Pharmacology. 18: 491-496. PMID 7464814 |
0.639 |
|
| 1980 |
Beerman TA, Gutai MW. DNA damage in neocarzinostatin-, macromomycin-, and bleomycin-treated SV40 virions Molecular Pharmacology. 17: 388-394. PMID 6156402 |
0.645 |
|
| 1979 |
Beerman TA. Strand scission of superhelical and linear duplex DNAs by the antitumor protein macromomycin. Relationship of in vitro DNA damage to cell growth inhibition Bba Section Nucleic Acids and Protein Synthesis. 564: 361-371. PMID 159074 DOI: 10.1016/0005-2787(79)90028-5 |
0.63 |
|
| 1978 |
Beerman TA. Cellular DNA damage by the antitumor protein macromomycin and its relationship to cell growth inhibition Biochemical and Biophysical Research Communications. 83: 908-914. PMID 708441 DOI: 10.1016/0006-291X(78)91481-X |
0.539 |
|
| 1978 |
Goldberg IH, Kappen LS, Beerman TA. The nature and mechanism of the damage induced in DNA by a protein antibiotic Advances in Enzyme Regulation. 16: 239-254. PMID 151496 DOI: 10.1016/0065-2571(78)90076-6 |
0.655 |
|
| 1977 |
Poon R, Beerman TA, Goldberg IH. Characterization of DNA strand breakage in vitro by the antitumor protein neocarzinostatin Biochemistry. 16: 486-493. PMID 189801 DOI: 10.1021/Bi00622A023 |
0.496 |
|
| 1977 |
Beerman TA, Poon R, Goldberg IH. Single-strand nicking of DNA in vitro by neocarzinostatin and its possible relationship to the mechanism of drug action Bba Section Nucleic Acids and Protein Synthesis. 475: 294-306. PMID 139167 DOI: 10.1016/0005-2787(77)90020-X |
0.546 |
|
| 1977 |
Beerman TA, Goldberg IH. The relationship between DNA strand-scission and DNA synthesis inhibition in HeLa cells treated with neocarzinostatin Bba Section Nucleic Acids and Protein Synthesis. 475: 281-293. PMID 139166 DOI: 10.1016/0005-2787(77)90019-3 |
0.644 |
|
| 1976 |
Beerman TA, Goldberg IH, Kappen LS, Poon R, Suzuki H. Molecular basis of action of cytotoxic antibiotics Advances in Enzyme Regulation. 14: 207-225. PMID 9788 DOI: 10.1016/0065-2571(76)90014-5 |
0.518 |
|
| 1975 |
Beerman TA, Goldberg IH, Poon R. The interaction of the protein antibiotic neocarzinostatin with DNA Excerpta Medica, Ics No. 353. 347-352. |
0.466 |
|
| 1974 |
Beerman TA, Goldberg IH. DNA strand scission by the antitumor protein neocarzinostatin Biochemical and Biophysical Research Communications. 59: 1254-1261. PMID 4369938 DOI: 10.1016/0006-291X(74)90449-5 |
0.65 |
|
| 1973 |
Beerman TA, Lebowitz J. Further analysis of the altered secondary structure of superhelical DNA. Sensitivity to methylmercuric hydroxide a chemical probe for unpaired bases Journal of Molecular Biology. 79. PMID 4758062 DOI: 10.1016/0022-2836(73)90398-7 |
0.548 |
|
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