| Year |
Citation |
Score |
| 2020 |
Deryugina E, Carré A, Ardi V, Muramatsu T, Schmidt J, Pham C, Quigley JP. Neutrophil Elastase Facilitates Tumor Cell Intravasation and Early Metastatic Events. Iscience. 23: 101799. PMID 33299970 DOI: 10.1016/j.isci.2020.101799 |
0.308 |
|
| 2020 |
Kryza T, Khan T, Puttick S, Li C, Sokolowski KA, Tse BW, Cuda T, Lyons N, Gough M, Yin J, Parkin A, Deryugina EI, Quigley JP, Law RHP, Whisstock JC, et al. Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma. Theranostics. 10: 4116-4133. PMID 32226543 DOI: 10.7150/Thno.43589 |
0.333 |
|
| 2019 |
Swarnakar S, Quigley JP, Armstrong PB. The Plasma-Based Cytolytic System of the American Horseshoe Crab, Limulus polyphemus: Cooperative Interaction of the Sialic Acid-Binding Lectin Limulin and Thiol Ester-Reacted α2-Macroglobulin. The Biological Bulletin. 191: 298. PMID 29220255 DOI: 10.1086/Bblv191N2P298 |
0.338 |
|
| 2019 |
Swarnakar S, Quigley JP, Armstrong PB. Potentiation of Limulin-Mediated Cytolysis by Thiol Ester-Reacted Forms of Limulus α2-Macroglobulin: Identification of Functionally Important Domains. The Biological Bulletin. 191: 299-300. PMID 29220251 DOI: 10.1086/Bblv191N2P299 |
0.345 |
|
| 2019 |
Quigley JP, Corcoran G, Armstrong PB. A Hemolytic Activity Secreted by the Endotoxin-Challenged Horseshoe Crab: A Novel Immune System Operating at the Surface of the Carapace. The Biological Bulletin. 193: 273. PMID 28575616 DOI: 10.1086/Bblv193N2P273 |
0.312 |
|
| 2019 |
Swarnakar S, Melchior R, Quigley JP, Armstrong PB. Regulation of the Plasma Cytolytic Pathway of Limulus polyphemus by {alpha}2-Macroglobulin. The Biological Bulletin. 189: 226-227. PMID 27768474 DOI: 10.1086/Bblv189N2P226 |
0.305 |
|
| 2019 |
Aimes RT, Quigley JP, Swarnakar S, Strickland DK, Armstrong PB. Preliminary Investigations on the Scavenger Receptors of the Amebocyte of the American Horseshoe Crab, Limulus polyphemus. The Biological Bulletin. 189: 225-226. PMID 27768473 DOI: 10.1086/Bblv189N2P225 |
0.346 |
|
| 2018 |
Deryugina EI, Zajac E, Zilberberg L, Muramatsu T, Joshi G, Dabovic B, Rifkin D, Quigley JP. LTBP3 promotes early metastatic events during cancer cell dissemination. Oncogene. PMID 29348457 DOI: 10.1038/S41388-017-0075-1 |
0.407 |
|
| 2018 |
Maxwell PJ, McKechnie M, Duddy O, Armstrong CW, Manley JM, Ong CW, Worthington J, Deryugina E, Quigley JP, Zoubeidi A, Waugh DJJ, LaBonte MJ. Abstract A087: Enzalutamide-induced hypoxia attenuates response and promotes resistance to enzalutamide in preclinical models of prostate cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Prca2017-A087 |
0.326 |
|
| 2016 |
Weber MR, Zuka M, Lorger M, Tschan M, Torbett BE, Zijlstra A, Quigley JP, Staflin K, Eliceiri BP, Krueger JS, Marchese P, Ruggeri ZM, Felding BH. Activated tumor cell integrin αvβ3 cooperates with platelets to promote extravasation and metastasis from the blood stream. Thrombosis Research. 140: S27-36. PMID 27067975 DOI: 10.1016/S0049-3848(16)30095-0 |
0.386 |
|
| 2015 |
Minder P, Zajac E, Quigley JP, Deryugina EI. EGFR regulates the development and microarchitecture of intratumoral angiogenic vasculature capable of sustaining cancer cell intravasation. Neoplasia (New York, N.Y.). 17: 634-49. PMID 26408256 DOI: 10.1016/J.Neo.2015.08.002 |
0.377 |
|
| 2015 |
Deryugina EI, Quigley JP. Tumor angiogenesis: MMP-mediated induction of intravasation- and metastasis-sustaining neovasculature. Matrix Biology : Journal of the International Society For Matrix Biology. 44: 94-112. PMID 25912949 DOI: 10.1016/J.Matbio.2015.04.004 |
0.423 |
|
| 2015 |
Vandooren J, Born B, Solomonov I, Zajac E, Saldova R, Senske M, Ugarte-Berzal E, Martens E, Van den Steen PE, Van Damme J, Garcia-Pardo A, Froeyen M, Deryugina EI, Quigley JP, Moestrup SK, et al. Circular trimers of gelatinase B/matrix metalloproteinase-9 constitute a distinct population of functional enzyme molecules differentially regulated by tissue inhibitor of metalloproteinases-1. The Biochemical Journal. 465: 259-70. PMID 25360794 DOI: 10.1042/Bj20140418 |
0.49 |
|
| 2015 |
Minder P, Deryugina EI, Quigley JP. Abstract A06: The role of the epidermal growth factor receptor (EGFR) in primary tumor cell escape and development of an intravasation-sustaining vasculature Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-A06 |
0.364 |
|
| 2014 |
Deryugina EI, Zajac E, Juncker-Jensen A, Kupriyanova TA, Welter L, Quigley JP. Tissue-infiltrating neutrophils constitute the major in vivo source of angiogenesis-inducing MMP-9 in the tumor microenvironment. Neoplasia (New York, N.Y.). 16: 771-88. PMID 25379015 DOI: 10.1016/J.Neo.2014.08.013 |
0.488 |
|
| 2014 |
Deryugina EI, Kiosses WB, Quigley JP. Abstract PR14: Quantitative and multiparameter analysis of tumor cell intravasation Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-Pr14 |
0.363 |
|
| 2013 |
Zajac E, Schweighofer B, Kupriyanova TA, Juncker-Jensen A, Minder P, Quigley JP, Deryugina EI. Angiogenic capacity of M1- and M2-polarized macrophages is determined by the levels of TIMP-1 complexed with their secreted proMMP-9. Blood. 122: 4054-67. PMID 24174628 DOI: 10.1182/Blood-2013-05-501494 |
0.332 |
|
| 2013 |
Juncker-Jensen A, Deryugina EI, Rimann I, Zajac E, Kupriyanova TA, Engelholm LH, Quigley JP. Tumor MMP-1 activates endothelial PAR1 to facilitate vascular intravasation and metastatic dissemination. Cancer Research. 73: 4196-211. PMID 23687338 DOI: 10.1158/0008-5472.Can-12-4495 |
0.515 |
|
| 2013 |
Low-Marchelli JM, Ardi VC, Vizcarra EA, van Rooijen N, Quigley JP, Yang J. Twist1 induces CCL2 and recruits macrophages to promote angiogenesis. Cancer Research. 73: 662-71. PMID 23329645 DOI: 10.1158/0008-5472.Can-12-0653 |
0.405 |
|
| 2013 |
Zajac E, Schweighofer B, Casar B, Kupriyanova T, Rimann I, Juncker-Jensen A, Deryugina E, Quigley JP. Abstract PR10: High angiogenic capacity of inflammatory neutrophils and polarized M2 macrophages is determined by production of MMP-9 unencumbered by its natural inhibitor TIMP-1 Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-Pr10 |
0.411 |
|
| 2013 |
Deryugina EI, Quigley JP. Abstract C26: Molecular determinants of the intravasation step in cancer metastasis Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-C26 |
0.483 |
|
| 2013 |
Juncker-Jensen A, Casar B, Rimann I, Zajac E, Kupriyanova TA, Deryugina EI, Quigley JP. Abstract C18: Matrix metalloproteinase-1 (MMP-1) facilitates intravasation and vascular dissemination of human carcinoma cells by regulating the microarchitecture and permeability of intratumoral vasculature Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-C18 |
0.491 |
|
| 2012 |
Casar B, Rimann I, Kato H, Shattil SJ, Quigley JP, Deryugina EI. In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated β1 integrin and induction of FAK/PI3K/Akt motility signaling. Oncogene. 33: 255-68. PMID 23208492 DOI: 10.1038/Onc.2012.547 |
0.384 |
|
| 2012 |
Deryugina EI, Quigley JP. Cell surface remodeling by plasmin: a new function for an old enzyme. Journal of Biomedicine & Biotechnology. 2012: 564259. PMID 23097597 DOI: 10.1155/2012/564259 |
0.462 |
|
| 2012 |
Kato H, Liao Z, Mitsios JV, Wang HY, Deryugina EI, Varner JA, Quigley JP, Shattil SJ. The primacy of β1 integrin activation in the metastatic cascade. Plos One. 7: e46576. PMID 23056350 DOI: 10.1371/Journal.Pone.0046576 |
0.347 |
|
| 2012 |
Botkjaer KA, Deryugina EI, Dupont DM, Gårdsvoll H, Bekes EM, Thuesen CK, Chen Z, Chen Z, Ploug M, Quigley JP, Andreasen PA. Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism. Molecular Cancer Research : McR. 10: 1532-43. PMID 23038812 DOI: 10.1158/1541-7786.Mcr-12-0349 |
0.463 |
|
| 2012 |
Casar B, He Y, Iconomou M, Hooper JD, Quigley JP, Deryugina EI. Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells. Oncogene. 31: 3924-38. PMID 22179830 DOI: 10.1038/Onc.2011.555 |
0.388 |
|
| 2011 |
Bekes EM, Deryugina EI, Kupriyanova TA, Zajac E, Botkjaer KA, Andreasen PA, Quigley JP. Activation of pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells. Neoplasia (New York, N.Y.). 13: 806-21. PMID 21969814 DOI: 10.1593/Neo.11704 |
0.457 |
|
| 2011 |
Bekes EM, Schweighofer B, Kupriyanova TA, Zajac E, Ardi VC, Quigley JP, Deryugina EI. Tumor-recruited neutrophils and neutrophil TIMP-free MMP-9 regulate coordinately the levels of tumor angiogenesis and efficiency of malignant cell intravasation. The American Journal of Pathology. 179: 1455-70. PMID 21741942 DOI: 10.1016/J.Ajpath.2011.05.031 |
0.452 |
|
| 2011 |
Botkjaer KA, Fogh S, Bekes EC, Chen Z, Blouse GE, Jensen JM, Mortensen KK, Huang M, Deryugina E, Quigley JP, Declerck PJ, Andreasen PA. Targeting the autolysis loop of urokinase-type plasminogen activator with conformation-specific monoclonal antibodies. The Biochemical Journal. 438: 39-51. PMID 21635223 DOI: 10.1042/Bj20110129 |
0.371 |
|
| 2010 |
He Y, Wortmann A, Burke LJ, Reid JC, Adams MN, Abdul-Jabbar I, Quigley JP, Leduc R, Kirchhofer D, Hooper JD. Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKCdelta. The Journal of Biological Chemistry. 285: 26162-73. PMID 20551327 DOI: 10.1074/Jbc.M109.096453 |
0.364 |
|
| 2010 |
Fukuchi K, Steiniger SC, Deryugina E, Liu Y, Lowery CA, Gloeckner C, Zhou B, Kaufmann GF, Quigley JP, Janda KD. Inhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1. Molecular Pharmaceutics. 7: 245-53. PMID 19916495 DOI: 10.1021/Mp900236T |
0.392 |
|
| 2010 |
Heida NM, Leifheit-Nestler M, Schroeter MR, Müller JP, Cheng IF, Henkel S, Limbourg A, Limbourg FP, Alves F, Quigley JP, Ruggeri ZM, Hasenfuss G, Konstantinides S, Schäfer K. Leptin enhances the potency of circulating angiogenic cells via src kinase and integrin (alpha)vbeta5: implications for angiogenesis in human obesity. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 200-6. PMID 19910644 DOI: 10.1161/Atvbaha.109.192807 |
0.303 |
|
| 2010 |
Deryugina EI, Quigley JP. Pleiotropic roles of matrix metalloproteinases in tumor angiogenesis: contrasting, overlapping and compensatory functions. Biochimica Et Biophysica Acta. 1803: 103-20. PMID 19800930 DOI: 10.1016/J.Bbamcr.2009.09.017 |
0.492 |
|
| 2009 |
Subauste MC, Kupriyanova TA, Conn EM, Ardi VC, Quigley JP, Deryugina EI. Evaluation of metastatic and angiogenic potentials of human colon carcinoma cells in chick embryo model systems. Clinical & Experimental Metastasis. 26: 1033-47. PMID 19842048 DOI: 10.1007/S10585-009-9293-4 |
0.386 |
|
| 2009 |
Conn EM, Botkjaer KA, Kupriyanova TA, Andreasen PA, Deryugina EI, Quigley JP. Comparative analysis of metastasis variants derived from human prostate carcinoma cells: roles in intravasation of VEGF-mediated angiogenesis and uPA-mediated invasion. The American Journal of Pathology. 175: 1638-52. PMID 19729488 DOI: 10.2353/Ajpath.2009.090384 |
0.459 |
|
| 2009 |
Deryugina EI, Conn EM, Wortmann A, Partridge JJ, Kupriyanova TA, Ardi VC, Hooper JD, Quigley JP. Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination. Molecular Cancer Research : McR. 7: 1197-211. PMID 19671673 DOI: 10.1158/1541-7786.Mcr-09-0100 |
0.429 |
|
| 2009 |
Ardi VC, Van den Steen PE, Opdenakker G, Schweighofer B, Deryugina EI, Quigley JP. Neutrophil MMP-9 proenzyme, unencumbered by TIMP-1, undergoes efficient activation in vivo and catalytically induces angiogenesis via a basic fibroblast growth factor (FGF-2)/FGFR-2 pathway. The Journal of Biological Chemistry. 284: 25854-66. PMID 19608737 DOI: 10.1074/Jbc.M109.033472 |
0.504 |
|
| 2009 |
Wortmann A, He Y, Deryugina EI, Quigley JP, Hooper JD. The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges. Iubmb Life. 61: 723-30. PMID 19514048 DOI: 10.1002/Iub.198 |
0.327 |
|
| 2009 |
Blouse GE, Bøtkjaer KA, Deryugina E, Byszuk AA, Jensen JM, Mortensen KK, Quigley JP, Andreasen PA. A novel mode of intervention with serine protease activity: targeting zymogen activation. The Journal of Biological Chemistry. 284: 4647-57. PMID 19047064 DOI: 10.1074/Jbc.M804922200 |
0.413 |
|
| 2008 |
Deryugina EI, Quigley JP. Chapter 2. Chick embryo chorioallantoic membrane models to quantify angiogenesis induced by inflammatory and tumor cells or purified effector molecules. Methods in Enzymology. 444: 21-41. PMID 19007659 DOI: 10.1016/S0076-6879(08)02802-4 |
0.379 |
|
| 2008 |
Deryugina EI, Quigley JP. Chick embryo chorioallantoic membrane model systems to study and visualize human tumor cell metastasis. Histochemistry and Cell Biology. 130: 1119-30. PMID 19005674 DOI: 10.1007/S00418-008-0536-2 |
0.367 |
|
| 2008 |
Conn EM, Madsen MA, Cravatt BF, Ruf W, Deryugina EI, Quigley JP. Cell surface proteomics identifies molecules functionally linked to tumor cell intravasation. The Journal of Biological Chemistry. 283: 26518-27. PMID 18658134 DOI: 10.1074/Jbc.M803337200 |
0.336 |
|
| 2008 |
Zijlstra A, Lewis J, Degryse B, Stuhlmann H, Quigley JP. The inhibition of tumor cell intravasation and subsequent metastasis via regulation of in vivo tumor cell motility by the tetraspanin CD151. Cancer Cell. 13: 221-34. PMID 18328426 DOI: 10.1016/J.Ccr.2008.01.031 |
0.384 |
|
| 2008 |
Ramsay AJ, Reid JC, Velasco G, Quigley JP, Hooper JD. The type II transmembrane serine protease matriptase-2--identification, structural features, enzymology, expression pattern and potential roles. Frontiers in Bioscience : a Journal and Virtual Library. 13: 569-79. PMID 17981570 DOI: 10.2741/2702 |
0.331 |
|
| 2008 |
Quigley JP. Induction of physiologic and pathologic angiogenesis by TIMP-free proMMP-9 derived uniquely from inflammatory neutrophils Matrix Biology. 27: 11. DOI: 10.1016/J.Matbio.2008.09.223 |
0.336 |
|
| 2007 |
Ardi VC, Kupriyanova TA, Deryugina EI, Quigley JP. Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 104: 20262-7. PMID 18077379 DOI: 10.1073/Pnas.0706438104 |
0.556 |
|
| 2007 |
Partridge JJ, Madsen MA, Ardi VC, Papagiannakopoulos T, Kupriyanova TA, Quigley JP, Deryugina EI. Functional analysis of matrix metalloproteinases and tissue inhibitors of metalloproteinases differentially expressed by variants of human HT-1080 fibrosarcoma exhibiting high and low levels of intravasation and metastasis. The Journal of Biological Chemistry. 282: 35964-77. PMID 17895241 DOI: 10.1074/Jbc.M705993200 |
0.445 |
|
| 2006 |
Zijlstra A, Quigley JP. The DARC side of metastasis: shining a light on KAI1-mediated metastasis suppression in the vascular tunnel. Cancer Cell. 10: 177-8. PMID 16959609 DOI: 10.1016/J.Ccr.2006.08.012 |
0.378 |
|
| 2006 |
Deryugina EI, Quigley JP. Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Reviews. 25: 9-34. PMID 16680569 DOI: 10.1007/S10555-006-7886-9 |
0.488 |
|
| 2006 |
Madsen MA, Deryugina EI, Niessen S, Cravatt BF, Quigley JP. Activity-based protein profiling implicates urokinase activation as a key step in human fibrosarcoma intravasation. The Journal of Biological Chemistry. 281: 15997-6005. PMID 16611636 DOI: 10.1074/Jbc.M601223200 |
0.401 |
|
| 2006 |
Zijlstra A, Seandel M, Kupriyanova TA, Partridge JJ, Madsen MA, Hahn-Dantona EA, Quigley JP, Deryugina EI. Proangiogenic role of neutrophil-like inflammatory heterophils during neovascularization induced by growth factors and human tumor cells. Blood. 107: 317-27. PMID 16174763 DOI: 10.1182/Blood-2005-04-1458 |
0.759 |
|
| 2005 |
Deryugina EI, Zijlstra A, Partridge JJ, Kupriyanova TA, Madsen MA, Papagiannakopoulos T, Quigley JP. Unexpected effect of matrix metalloproteinase down-regulation on vascular intravasation and metastasis of human fibrosarcoma cells selected in vivo for high rates of dissemination. Cancer Research. 65: 10959-69. PMID 16322244 DOI: 10.1158/0008-5472.Can-05-2228 |
0.454 |
|
| 2005 |
Blancafort P, Chen EI, Gonzalez B, Bergquist S, Zijlstra A, Guthy D, Brachat A, Brakenhoff RH, Quigley JP, Erdmann D, Barbas CF. Genetic reprogramming of tumor cells by zinc finger transcription factors. Proceedings of the National Academy of Sciences of the United States of America. 102: 11716-21. PMID 16081541 DOI: 10.1073/Pnas.0501162102 |
0.374 |
|
| 2005 |
Wilson S, Greer B, Hooper J, Zijlstra A, Walker B, Quigley J, Hawthorne S. The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells. The Biochemical Journal. 388: 967-72. PMID 15537383 DOI: 10.1042/Bj20041066 |
0.358 |
|
| 2004 |
Zijlstra A, Aimes RT, Zhu D, Regazzoni K, Kupriyanova T, Seandel M, Deryugina EI, Quigley JP. Collagenolysis-dependent angiogenesis mediated by matrix metalloproteinase-13 (collagenase-3). The Journal of Biological Chemistry. 279: 27633-45. PMID 15066996 DOI: 10.1074/Jbc.M313617200 |
0.776 |
|
| 2004 |
Weber MR, O’Sullivan D, Tschan MP, Torbett BE, Zijlstra A, Quigley JP, Felding-Habermann B. Understanding Hematogenous Breast Cancer Metastasis: Tumor Cell Integrin Activation Matters. Blood. 104: 2613-2613. DOI: 10.1182/Blood.V104.11.2613.2613 |
0.409 |
|
| 2003 |
Banke IJ, Arlt MJ, Pennington C, Kopitz C, Steinmetzer T, Schweinitz A, Gansbacher B, Quigley JP, Edwards DR, Stürzebecher J, Krüger A. Increase of anti-metastatic efficacy by selectivity- but not affinity-optimization of synthetic serine protease inhibitors. Biological Chemistry. 384: 1515-25. PMID 14669995 DOI: 10.1515/Bc.2003.168 |
0.346 |
|
| 2003 |
Quigley JP. Matrix metalloproteases and tumor dissemination. Pathophysiology of Haemostasis and Thrombosis. 33: 62-3. PMID 12955008 DOI: 10.1159/000073297 |
0.502 |
|
| 2003 |
Netzel-Arnett S, Hooper JD, Szabo R, Madison EL, Quigley JP, Bugge TH, Antalis TM. Membrane anchored serine proteases: a rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer. Cancer Metastasis Reviews. 22: 237-58. PMID 12784999 DOI: 10.1023/A:1023003616848 |
0.361 |
|
| 2003 |
Hooper JD, Campagnolo L, Goodarzi G, Truong TN, Stuhlmann H, Quigley JP. Mouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissues. The Biochemical Journal. 373: 689-702. PMID 12744720 DOI: 10.1042/Bj20030390 |
0.309 |
|
| 2003 |
Hooper JD, Zijlstra A, Aimes RT, Liang H, Claassen GF, Tarin D, Testa JE, Quigley JP. Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen. Oncogene. 22: 1783-94. PMID 12660814 DOI: 10.1038/Sj.Onc.1206220 |
0.404 |
|
| 2003 |
Aimes RT, Zijlstra A, Hooper JD, Ogbourne SM, Sit ML, Fuchs S, Gotley DC, Quigley JP, Antalis TM. Endothelial cell serine proteases expressed during vascular morphogenesis and angiogenesis. Thrombosis and Haemostasis. 89: 561-72. PMID 12624642 DOI: 10.1055/S-0037-1613388 |
0.401 |
|
| 2003 |
Aimes RT, Regazzoni K, Quigley JP. Human/chicken urokinase chimeras demonstrate sequences outside the serine protease domain that dictate autoactivation. Thrombosis and Haemostasis. 89: 382-92. PMID 12574820 DOI: 10.1055/S-0037-1613456 |
0.351 |
|
| 2001 |
Rozanov DV, Deryugina EI, Ratnikov BI, Monosov EZ, Marchenko GN, Quigley JP, Strongin AY. Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells. The Journal of Biological Chemistry. 276: 25705-14. PMID 11335709 DOI: 10.1074/Jbc.M007921200 |
0.505 |
|
| 2001 |
Seandel M, Noack-Kunnmann K, Zhu D, Aimes RT, Quigley JP. Growth factor-induced angiogenesis in vivo requires specific cleavage of fibrillar type I collagen. Blood. 97: 2323-32. PMID 11290594 DOI: 10.1182/Blood.V97.8.2323 |
0.748 |
|
| 2001 |
Hooper JD, Clements JA, Quigley JP, Antalis TM. Type II transmembrane serine proteases. Insights into an emerging class of cell surface proteolytic enzymes Journal of Biological Chemistry. 276: 857-860. PMID 11060317 DOI: 10.1074/Jbc.R000020200 |
0.459 |
|
| 2000 |
Loskutoff DJ, Quigley JP. PAI-1, fibrosis, and the elusive provisional fibrin matrix Journal of Clinical Investigation. 106: 1441-1443. PMID 11120750 DOI: 10.1172/Jci11765 |
0.407 |
|
| 2000 |
Hahn-Dantona EA, Aimes RT, Quigley JP. The isolation, characterization, and molecular cloning of a 75-kDa gelatinase B-like enzyme, a member of the matrix metalloproteinase (MMP) family. An avian enzyme that is MMP-9-like in its cell expression pattern but diverges from mammalian gelatinase B in sequence and biochemical properties. The Journal of Biological Chemistry. 275: 40827-38. PMID 11010969 DOI: 10.1074/Jbc.M006234200 |
0.799 |
|
| 2000 |
Cai DH, Vollberg TM, Hahn-Dantona E, Quigley JP, Brauer PR. MMP-2 expression during early avian cardiac and neural crest morphogenesis. The Anatomical Record. 259: 168-79. PMID 10820319 DOI: 10.1002/(Sici)1097-0185(20000601)259:2<168::Aid-Ar7>3.0.Co;2-U |
0.794 |
|
| 1999 |
Nielsen-Preiss SM, Quigley JP, Testa JE. Co-inoculation of human and murine carcinoma cells induces reciprocal suppression of metastasis by both cell lines. Clinical & Experimental Metastasis. 17: 489-96. PMID 10763914 DOI: 10.1023/A:1006607716061 |
0.742 |
|
| 1999 |
Hahn-Dantona E, Ramos-DeSimone N, Sipley J, Nagase H, French DL, Quigley JP. Activation of proMMP-9 by a plasmin/MMP-3 cascade in a tumor cell model. Regulation by tissue inhibitors of metalloproteinases. Annals of the New York Academy of Sciences. 878: 372-87. PMID 10415742 DOI: 10.1111/J.1749-6632.1999.Tb07696.X |
0.807 |
|
| 1999 |
Ramos-DeSimone N, Hahn-Dantona E, Sipley J, Nagase H, French DL, Quigley JP. Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion. The Journal of Biological Chemistry. 274: 13066-76. PMID 10224058 DOI: 10.1074/Jbc.274.19.13066 |
0.806 |
|
| 1998 |
Quigley JP, Armstrong PB. Tumor cell intravasation alu-cidated: the chick embryo opens the window. Cell. 94: 281-4. PMID 9708729 DOI: 10.1016/S0092-8674(00)81470-1 |
0.331 |
|
| 1998 |
Alexander DS, Sipley JD, Quigley JP. Autoactivation of avian urokinase-type plasminogen activator (uPA). A novel mode of initiation of the uPA/plasmin cascade. The Journal of Biological Chemistry. 273: 7457-61. PMID 9516444 DOI: 10.1074/Jbc.273.13.7457 |
0.322 |
|
| 1998 |
Aimes RT, Li LH, Weaver B, Hawkes S, Hahn-Dantona EA, Quigley JP. Cloning, expression, and characterization of chicken tissue inhibitor of metalloproteinase-2 (TIMP-2) in normal and transformed chicken embryo fibroblasts. Journal of Cellular Physiology. 174: 342-52. PMID 9462696 DOI: 10.1002/(Sici)1097-4652(199803)174:3<342::Aid-Jcp8>3.0.Co;2-O |
0.798 |
|
| 1997 |
Sipley JD, Alexander DS, Testa JE, Quigley JP. Introduction of an RRHR motif into chicken urokinase-type plasminogen activator (ch-uPA) confers sensitivity to plasminogen activator inhibitor (PAI)-1 and PAI-2 and allows ch-uPA-mediated extracellular matrix degradation to be controlled by PAI-1. Proceedings of the National Academy of Sciences of the United States of America. 94: 2933-8. PMID 9096324 DOI: 10.1073/Pnas.94.7.2933 |
0.326 |
|
| 1996 |
Alexander DS, Aimes RT, Quigley JP. What structure and function of avian plasminogen activator and matrix metalloproteinase-2 reveal about their counterpart mammalian enzymes, their regulation and their role in tumor invasion. Enzyme & Protein. 49: 38-58. PMID 8796996 DOI: 10.1159/000468615 |
0.438 |
|
| 1996 |
Brooks PC, Strömblad S, Sanders LC, von Schalscha TL, Aimes RT, Stetler-Stevenson WG, Quigley JP, Cheresh DA. Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Cell. 85: 683-93. PMID 8646777 DOI: 10.1016/S0092-8674(00)81235-0 |
0.446 |
|
| 1995 |
Aimes RT, Quigley JP. Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments. The Journal of Biological Chemistry. 270: 5872-6. PMID 7890717 DOI: 10.1074/Jbc.270.11.5872 |
0.478 |
|
| 1995 |
Testa J, Stefansson S, Sioussat T, Quigley J. Avian urokinase-type plasminogen activator (u-PA) lacks the putative binding site for plasminogen activator inhibitor (PAI) and is resistant to inhibition by human PAI-1 and PAI-2 Fibrinolysis. 9: 93-99. DOI: 10.1016/S0268-9499(95)80070-0 |
0.316 |
|
| 1994 |
Aimes RT, French DL, Quigley JP. Cloning of a 72 kDa matrix metalloproteinase (gelatinase) from chicken embryo fibroblasts using gene family PCR: expression of the gelatinase increases upon malignant transformation. The Biochemical Journal. 300: 729-36. PMID 8010954 DOI: 10.1042/Bj3000729 |
0.426 |
|
| 1994 |
Stefansson S, Aimes RT, Seward NB, Alexander DS, Quigley JP. Native TIMP-free 70 kDa progelatinase (MMP-2) secreted at elevated levels by RSV transformed fibroblasts. Journal of Cellular Physiology. 161: 419-28. PMID 7962125 DOI: 10.1002/Jcp.1041610304 |
0.468 |
|
| 1994 |
Armstrong PB, Sottrup-Jensen L, Ikai A, Srimal S, Quigley JP. Alpha 2M in the horseshoe crab. A structural and functional invertebrate homologue. Annals of the New York Academy of Sciences. 737: 188-201. PMID 7524396 DOI: 10.1111/J.1749-6632.1994.Tb44312.X |
0.304 |
|
| 1993 |
Nielsen-Preiss SM, Quigley JP. Detection and characterization of low abundance cellular proteins that specifically increase upon loss of the metastatic phenotype. Journal of Cellular Biochemistry. 51: 219-35. PMID 8440754 DOI: 10.1002/Jcb.240510214 |
0.744 |
|
| 1993 |
Quigley JP, Braithwaite RS, Armstrong PB. Matrix metalloproteases of the developing sea urchin embryo. Differentiation; Research in Biological Diversity. 54: 19-23. PMID 8405771 DOI: 10.1111/J.1432-0436.1993.Tb00655.X |
0.394 |
|
| 1993 |
Aimes RT, Nielsen-Preiss SM, Quigley JP. Resolution of TIMP-free and TIMP-complexed 70kDa progelatinase from culture medium of Rous sarcoma virus-transformed chicken embryo fibroblasts. Agents and Actions. Supplements. 42: 227-43. PMID 8395138 DOI: 10.1007/978-3-0348-7397-0_18 |
0.768 |
|
| 1993 |
Brooks PC, Lin JM, French DL, Quigley JP. Subtractive immunization yields monoclonal antibodies that specifically inhibit metastasis. The Journal of Cell Biology. 122: 1351-9. PMID 8376467 DOI: 10.1083/Jcb.122.6.1351 |
0.364 |
|
| 1993 |
Schnaper HW, Grant DS, Stetler-Stevenson WG, Fridman R, D'Orazi G, Murphy AN, Bird RE, Hoythya M, Fuerst TR, French DL, Quigley JP, Kleinman HK. Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro Journal of Cellular Physiology. 156: 235-246. PMID 8344982 DOI: 10.1002/Jcp.1041560204 |
0.45 |
|
| 1993 |
Ramos-DeSimone N, Moll UM, Quigley JP, French DL. Inhibition of matrix metalloproteinase 9 activation by a specific monoclonal antibody. Hybridoma. 12: 349-63. PMID 8244415 DOI: 10.1089/Hyb.1993.12.349 |
0.506 |
|
| 1991 |
Testa JE, Quigley JP. Reversal of misfortune: TIMP-2 inhibits tumor cell invasion Journal of the National Cancer Institute. 83: 740-742. PMID 2041046 DOI: 10.1093/Jnci/83.11.740 |
0.411 |
|
| 1991 |
Chen JM, Aimes RT, Ward GR, Youngleib GL, Quigley JP. Isolation and characterization of a 70-kDa metalloprotease (gelatinase) that is elevated in Rous sarcoma virus-transformed chicken embryo fibroblasts. The Journal of Biological Chemistry. 266: 5113-21. PMID 1848240 |
0.323 |
|
| 1991 |
Berkenpas MB, Quigley JP. Transformation-dependent activation of urokinase-type plasminogen activator by a plasmin-independent mechanism: involvement of cell surface membranes. Proceedings of the National Academy of Sciences of the United States of America. 88: 7768-72. PMID 1652763 DOI: 10.1073/Pnas.88.17.7768 |
0.374 |
|
| 1990 |
Armstrong PB, Quigley JP, Rickles FR. The Limulus Blood Cell Secretes α2-Macroglobulin When Activated. The Biological Bulletin. 178: 137-143. PMID 29314932 DOI: 10.2307/1541972 |
0.356 |
|
| 1990 |
Moll UM, Youngleib GL, Rosinski KB, Quigley JP. Tumor promoter-stimulated Mr 92,000 gelatinase secreted by normal and malignant human cells: isolation and characterization of the enzyme from HT1080 tumor cells. Cancer Research. 50: 6162-70. PMID 2169335 |
0.32 |
|
| 1990 |
Testa JE, Quigley JP. The role of urokinase-type plasminogen activator in aggressive tumor cell behavior Cancer and Metastasis Review. 9: 353-367. PMID 2129023 DOI: 10.1007/Bf00049524 |
0.442 |
|
| 1990 |
Quigley JP, Berkenpas MB, Aimes RT, Chen JM. Serine protease and metallo protease cascade systems involved in pericellular proteolysis. Cell Differentiation and Development : the Official Journal of the International Society of Developmental Biologists. 32: 263-75. PMID 1965954 DOI: 10.1016/0922-3371(90)90039-Y |
0.44 |
|
| 1989 |
Gold LI, Schwimmer R, Quigley JP. Human plasma fibronectin as a substrate for human urokinase. The Biochemical Journal. 262: 529-34. PMID 2529851 DOI: 10.1042/Bj2620529 |
0.438 |
|
| 1989 |
Berkenpas M, Quigley JP. Secretion of two-chain active plasminogen activator from rsv-transformed chicken embryo fibroblasts: Evidence for a plasmin-independent converting activity Fibrinolysis. 3: 3-4. DOI: 10.1016/0268-9499(89)90065-9 |
0.347 |
|
| 1987 |
Quigley JP, Gold LI, Schwimmer R, Sullivan LM. Limited cleavage of cellular fibronectin by plasminogen activator purified from transformed cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 2776-80. PMID 3033662 DOI: 10.1073/Pnas.84.9.2776 |
0.452 |
|
| 1986 |
Gordon JR, Quigley JP. Early spontaneous metastasis in the human epidermoid carcinoma HEp3/chick embryo model: Contribution of incidental colonization International Journal of Cancer. 38: 437-444. PMID 3744594 DOI: 10.1002/Ijc.2910380321 |
0.35 |
|
| 1986 |
Sullivan LM, Quigley JP. An anticatalytic monoclonal antibody to avian plasminogen activator: its effect on behavior of RSV-transformed chick fibroblasts. Cell. 45: 905-15. PMID 3011282 DOI: 10.1016/0092-8674(86)90565-9 |
0.408 |
|
| 1985 |
Fairbairn S, Gilbert R, Ojakian G, Schwimmer R, Quigley JP. The extracellular matrix of normal chick embryo fibroblasts: its effect on transformed chick fibroblasts and its proteolytic degradation by the transformants. The Journal of Cell Biology. 101: 1790-8. PMID 2997235 DOI: 10.1083/Jcb.101.5.1790 |
0.487 |
|
| 1985 |
Armstrong PB, Quigley JP. Proteinase inhibitory activity released from the horseshoe crab blood cell during exocytosis. Biochimica Et Biophysica Acta. 827: 453-9. PMID 2982412 DOI: 10.1016/0167-4838(85)90232-8 |
0.34 |
|
| 1985 |
Armstrong PB, Rossner MT, Quigley JP. An alpha 2-macroglobulinlike activity in the blood of chelicerate and mandibulate arthropods. The Journal of Experimental Zoology. 236: 1-9. PMID 2414391 DOI: 10.1002/Jez.1402360102 |
0.317 |
|
| 1984 |
Armstrong PB, Levin J, Quigley JP. Role of endogenous proteinase inhibitors in the regulation of the blood clotting system of the horseshoe crab, Limulus polyphemus. Thrombosis and Haemostasis. 52: 117-20. PMID 6084318 DOI: 10.1055/S-0038-1661152 |
0.37 |
|
| 1983 |
O'Donnell-Tormey J, Quigley JP. Detection and partial characterization of a chymostatin-sensitive endopeptidase in transformed fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 80: 344-8. PMID 6300832 DOI: 10.1073/Pnas.80.2.344 |
0.397 |
|
| 1982 |
Scheiner CJ, Quigley JP. Detection, identification, and partial characterization of serine proteases and esterases in biological systems Analytical Biochemistry. 122: 58-69. PMID 7048999 DOI: 10.1016/0003-2697(82)90251-2 |
0.38 |
|
| 1982 |
Liepkalns VA, Icard-Liepkalns C, Sommer AM, Quigley JP. Properties of cloned human glioblastoma cells. Release of a specific protease. Journal of the Neurological Sciences. 57: 257-64. PMID 6761410 DOI: 10.1016/0022-510X(82)90032-6 |
0.395 |
|
| 1981 |
Fletcher DJ, Quigley JP, Bauer GE, Noe BD. Characterization of proinsulin- and proglucagon-converting activities in isolated islet secretory granules. The Journal of Cell Biology. 90: 312-22. PMID 7026570 DOI: 10.1083/Jcb.90.2.312 |
0.323 |
|
| 1981 |
Long SD, Quigley JP, Troll W, Kennedy AR. Protease inhibitor antipain suppresses 12-O-tetradecanoyl-phorbol-13-acetate induction of plasminogen activator in transformable mouse embryo fibroblasts. Carcinogenesis. 2: 933-6. PMID 6794928 DOI: 10.1093/Carcin/2.9.933 |
0.373 |
|
| 1981 |
O'Donnell-Tormey J, Quigley JP. Inhibition of plasminogen activator release from transformed chicken fibroblasts by a protease inhibitor. Cell. 27: 85-95. PMID 6276025 DOI: 10.1016/0092-8674(81)90363-9 |
0.411 |
|
| 1980 |
Goldfarb RH, Quigley JP. Purification of plasminogen activator from Rous sarcoma virus transformed chick embryo fibroblasts treated with the tumor promoter phorbol 12-myristate 13-acetate Biochemistry. 19: 5463-5471. PMID 6257279 DOI: 10.1021/Bi00565A001 |
0.654 |
|
| 1980 |
Quigley JP, Goldfarb RH, Scheiner C, O'Donnell-Tormey J, Yeo TK. Plasminogen activator and the membrane of transformed cells. Progress in Clinical and Biological Research. 41: 773-96. PMID 6256777 |
0.637 |
|
| 1980 |
Fletcher DJ, Noe BD, Bauer GE, Quigley JP. Characterization of the conversion of a somatostatin precursor to somatostatin by islet secretory granules. Diabetes. 29: 593-9. PMID 6108270 DOI: 10.2337/Diab.29.8.593 |
0.323 |
|
| 1979 |
Quigley JP. Phorbol ester-induced morphological changes in transformed chick fibroblasts: Evidence for direct catalytic involvement of plasminogen activator Cell. 17: 131-141. PMID 222474 DOI: 10.1016/0092-8674(79)90301-5 |
0.412 |
|
| 1978 |
Martin BM, Quigley JP. Binding and internalization of 125I thrombin in chick embryo fibroblasts: possible role in mitogenesis. Journal of Cellular Physiology. 96: 155-64. PMID 670301 DOI: 10.1002/Jcp.1040960204 |
0.391 |
|
| 1978 |
Weissmann G, Finkelstein MC, Csernansky J, Quigley JP, Quinn RS, Techner L, Troll W, Dunham PB. Attack of sea urchin eggs by dogfish phagocytes: model of phagocyte-mediated cellular cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 75: 1825-9. PMID 347448 DOI: 10.1073/Pnas.75.4.1825 |
0.34 |
|
| 1978 |
Goldfarb RH, Quigley JP. Synergistic Effect of Tumor Virus Transformation and Tumor Promoter Treatment on the Production of Plasminogen Activator by Chick Embryo Fibroblasts Cancer Research. 38: 4601-4609. PMID 214228 |
0.608 |
|
| 1978 |
Zimmerman M, Quigley JP, Ashe B, Dorn C, Goldfarb R, Troll W. Direct fluorescent assay of urokinase and plasminogen activators of normal and malignant cells: kinetics and inhibitor profiles. Proceedings of the National Academy of Sciences of the United States of America. 75: 750-3. PMID 204931 DOI: 10.1073/Pnas.75.2.750 |
0.401 |
|
| 1976 |
Quigley JP. Association of a protease (plasminogen activator) with a specific membrane fraction isolated from transformed cells Journal of Cell Biology. 71: 472-486. PMID 993259 DOI: 10.1083/Jcb.71.2.472 |
0.376 |
|
| 1973 |
Ossowski L, Quigley JP, Kellerman GM, Reich E. Fibrinolysis associated with oncogenic transformation. Requirement of plasminogen for correlated changes in cellular morphology, colony formation in agar, and cell migration. The Journal of Experimental Medicine. 138: 1056-64. PMID 4355423 DOI: 10.1084/Jem.138.5.1056 |
0.354 |
|
| 1973 |
Unkeless JC, Tobia A, Ossowski L, Quigley JP, Rifkin DB, Reich E. An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. I. Chick embryo fibroblast cultures transformed by avian RNA tumor viruses. The Journal of Experimental Medicine. 137: 85-111. PMID 4347290 DOI: 10.1084/Jem.137.1.85 |
0.337 |
|
| 1973 |
Ossowski L, Unkeless JC, Tobia A, Quigley JP, Rifkin DB, Reich E. An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor viruses. The Journal of Experimental Medicine. 137: 112-26. PMID 4347288 DOI: 10.1084/Jem.137.1.112 |
0.379 |
|
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