Donald B. DeFranco - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Neuroscience Biology, Cell Biology

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Mizoguchi S, Mori K, Shin T, Wang Z, DeFranco DB, Yoshimura N, Mimata H. Effects of dutasteride in a rat model of chemically induced prostatic inflammation-Potential role of estrogen receptor β. The Prostate. PMID 32941694 DOI: 10.1002/Pros.24071  0.402
2020 Wang K, Pascal LE, Li F, Chen W, Dhir R, Balasubramani GK, DeFranco DB, Yoshimura N, He D, Wang Z. Tight junction protein claudin-1 is downregulated by TGF-β1 via MEK signaling in benign prostatic epithelial cells. The Prostate. PMID 32692865 DOI: 10.1002/Pros.24046  0.39
2020 Chen W, Pascal LE, Wang K, Dhir R, Sims AM, Campbell R, Gasper G, DeFranco DB, Yoshimura N, Wang Z. Differential impact of paired patient-derived BPH and normal adjacent stromal cells on benign prostatic epithelial cell growth in 3D culture. The Prostate. PMID 32659026 DOI: 10.1002/Pros.24044  0.382
2020 Berry K, Chandran U, Mu F, DeFranco D. MON-727 The Chromatin Landscape of Glucocorticoid Regulated Genes in Mouse Embryonic Neural Stem / Progenitor Cells Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.641  0.403
2020 Silswal N, Gupta H, Bean J, Burale S, Franks A, Berry KJ, Carey T, Oakley RH, Cidlowski J, Defranco D, Monaghan AP. SUN-LB53 Role of the Glucocorticoid Receptor Phosphorylation in Neural Development Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.2342  0.417
2020 Silswal N, Burale S, Bean J, Talib F, Gupta H, Goyal A, Shabbir A, DeFranco D, Monaghan AP. SUN-LB56 Steroid and Sex Specific Responses of Neural Stem Cells to Prenatal Dexamethasone versus Betamethasone Administration Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.2341  0.323
2019 Li F, Pascal LE, Stolz DB, Wang K, Zhou Y, Chen W, Xu Y, Chen Y, Dhir R, Parwani AV, Nelson JB, DeFranco DB, Yoshimura N, Balasubramani GK, Gingrich JR, et al. E-cadherin is downregulated in benign prostatic hyperplasia and required for tight junction formation and permeability barrier in the prostatic epithelial cell monolayer. The Prostate. PMID 31212363 DOI: 10.1002/Pros.23806  0.375
2019 Mizoguchi S, Wolf-Johnson AS, Ni J, Mori K, Suzuki T, Takaoka E, Mimata H, DeFranco DB, Wang Z, Birder LA, Yoshimura N. The role of prostaglandin and EP4 receptors in development of bladder overactivity in a rat model of chemically induced prostatic inflammation. Bju International. PMID 31166645 DOI: 10.1111/Bju.14845  0.408
2019 Ni J, Mizoguchi S, Bernardi K, Suzuki T, Kurobe M, Takaoka E, Wang Z, DeFranco DB, Tyagi P, Gu B, Yoshimura N. Long-lasting bladder overactivity and bladder afferent hyperexcitability in rats with chemically-induced prostatic inflammation. The Prostate. PMID 30900300 DOI: 10.1002/Pros.23794  0.35
2019 Funahashi Y, Takahashi R, Mizoguchi S, Suzuki T, Takaoka E, Ni J, Wang Z, DeFranco DB, de Groat WC, Tyagi P, Yoshimura N. Bladder overactivity and afferent hyperexcitability induced by prostate-to-bladder cross-sensitization in rats with prostatic inflammation. The Journal of Physiology. PMID 30666643 DOI: 10.1113/Jp277452  0.364
2018 Carson RA, Rudine AC, Tally SJ, Franks AL, Frahm KA, Waldman JK, Silswal N, Burale S, Phan JV, Chandran UR, Monaghan AP, DeFranco DB. Statins impact primary embryonic mouse neural stem cell survival, cell death, and fate through distinct mechanisms. Plos One. 13: e0196387. PMID 29738536 DOI: 10.1371/Journal.Pone.0196387  0.371
2018 Mizoguchi S, Wolf-Johnson AS, Suzuki T, Takaoka E, DeFranco DB, Wang Z, Birder LA, Yoshimura N. Mp45-06 Bladder Urothelial And Afferent Dysfunctions Underlying Bladder Overactivity In Rats With Chemically Induced Prostatic Inflammation The Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.1445  0.323
2017 Whirledge S, DeFranco DB. Glucocorticoid Signaling in Health and Disease: Insights from Tissue-Specific GR Knockout Mice. Endocrinology. PMID 29029225 DOI: 10.1210/En.2017-00728  0.38
2017 Mizoguchi S, Mori K, Wang Z, Liu T, Funahashi Y, Sato F, DeFranco DB, Yoshimura N, Mimata H. Effects of Estrogen Receptor β Stimulation in a Rat Model of Non-Bacterial Prostatic Inflammation. The Prostate. PMID 28181685 DOI: 10.1002/Pros.23320  0.395
2016 Liu TT, Grubisha MJ, Frahm KA, Wendell SG, Liu J, Ricke WA, Auchus RJ, DeFranco DB. Opposing Effects of Cyclooxygenase-2 (COX-2) on Estrogen Receptor β (ERβ) Response to 5α-reductase Inhibition in Prostate Epithelial Cells. The Journal of Biological Chemistry. PMID 27226548 DOI: 10.1074/Jbc.M115.711515  0.776
2015 Frahm KA, Peffer ME, Zhang JY, Luthra S, Chakka AB, Couger MB, Chandran UR, Monaghan AP, DeFranco DB. Research Resource: The Dexamethasone Transcriptome in Hypothalamic Embryonic Neural Stem Cells. Molecular Endocrinology (Baltimore, Md.). me20151258. PMID 26606517 DOI: 10.1210/Me.2015-1258  0.38
2015 Leach DA, Need EF, Toivanen R, Trotta AP, Palethorpe HM, Tamblyn DJ, Kopsaftis T, England GM, Smith E, Drew PA, Pinnock CB, Lee P, Holst J, Risbridger GP, Chopra S, ... DeFranco DB, et al. Erratum: Stromal androgen receptor regulates the composition of the microenvironment to influence prostate cancer outcome. Oncotarget. 6: 36923. PMID 26577649 DOI: 10.18632/Oncotarget.6263  0.416
2015 Wynder JL, Nicholson TM, DeFranco DB, Ricke WA. Estrogens and Male Lower Urinary Tract Dysfunction. Current Urology Reports. 16: 534. PMID 26156791 DOI: 10.1007/S11934-015-0534-6  0.433
2015 Leach DA, Need EF, Toivanen R, Trotta AP, Palenthorpe HM, Tamblyn DJ, Kopsaftis T, England GM, Smith E, Drew PA, Pinnock CB, Lee P, Holst J, Risbridger GP, Chopra S, ... DeFranco DB, et al. Stromal androgen receptor regulates the composition of the microenvironment to influence prostate cancer outcome. Oncotarget. 6: 16135-50. PMID 25965833 DOI: 10.18632/Oncotarget.3873  0.43
2015 Liu TT, Arango-Argoty G, Li Z, Lin Y, Kim SW, Dueck A, Ozsolak F, Monaghan AP, Meister G, DeFranco DB, John B. Noncoding RNAs that associate with YB-1 alter proliferation in prostate cancer cells. Rna (New York, N.Y.). 21: 1159-72. PMID 25904138 DOI: 10.1261/Rna.045559.114  0.309
2015 Peffer ME, Zhang JY, Umfrey L, Rudine AC, Monaghan AP, DeFranco DB. Minireview: the impact of antenatal therapeutic synthetic glucocorticoids on the developing fetal brain. Molecular Endocrinology (Baltimore, Md.). 29: 658-66. PMID 25763611 DOI: 10.1210/Me.2015-1042  0.33
2015 Funahashi Y, Wang Z, O'Malley KJ, Tyagi P, DeFranco DB, Gingrich JR, Takahashi R, Majima T, Gotoh M, Yoshimura N. Influence of E. coli-induced prostatic inflammation on expression of androgen-responsive genes and transforming growth factor beta 1 cascade genes in rats. The Prostate. 75: 381-9. PMID 25451715 DOI: 10.1002/Pros.22924  0.381
2014 Samarasinghe RA, Kanuparthi PS, Timothy Greenamyre J, DeFranco DB, Di Maio R. Transient muscarinic and glutamatergic stimulation of neural stem cells triggers acute and persistent changes in differentiation. Neurobiology of Disease. 70: 252-61. PMID 25003306 DOI: 10.1016/J.Nbd.2014.06.020  0.326
2014 Solomon JD, Heitzer MD, Liu TT, Beumer JH, Parise RA, Normolle DP, Leach DA, Buchanan G, DeFranco DB. VDR activity is differentially affected by Hic-5 in prostate cancer and stromal cells. Molecular Cancer Research : McR. 12: 1166-80. PMID 24825850 DOI: 10.1158/1541-7786.Mcr-13-0395  0.787
2014 Peffer ME, Chandran UR, Luthra S, Volonte D, Galbiati F, Garabedian MJ, Monaghan AP, DeFranco DB. Caveolin-1 regulates genomic action of the glucocorticoid receptor in neural stem cells. Molecular and Cellular Biology. 34: 2611-23. PMID 24777604 DOI: 10.1128/Mcb.01121-13  0.432
2014 Funahashi Y, O'Malley KJ, Kawamorita N, Tyagi P, DeFranco DB, Takahashi R, Gotoh M, Wang Z, Yoshimura N. Upregulation of androgen-responsive genes and transforming growth factor-β1 cascade genes in a rat model of non-bacterial prostatic inflammation. The Prostate. 74: 337-45. PMID 24446128 DOI: 10.1002/Pros.22668  0.375
2014 Leach DA, Need EF, Trotta AP, Grubisha MJ, DeFranco DB, Buchanan G. Hic-5 influences genomic and non-genomic actions of the androgen receptor in prostate myofibroblasts. Molecular and Cellular Endocrinology. 384: 185-99. PMID 24440747 DOI: 10.1016/J.Mce.2014.01.004  0.784
2013 Defranco DB. Editorial: molecular endocrinology articles in the spotlight for December 2013. Molecular Endocrinology (Baltimore, Md.). 27: 1983. PMID 24282125 DOI: 10.1210/Me.2013-1350  0.424
2013 Hunyady L, DeFranco DB. Editorial: Molecular Endocrinology special feature minireviews for August 2013: GPCRs in Endocrine physiology and pathophysiology. Molecular Endocrinology (Baltimore, Md.). 27: 1175-6. PMID 23894115 DOI: 10.1210/Me.2013-1198  0.408
2013 Tsiarli MA, Paula Monaghan A, Defranco DB. Differential subcellular localization of the glucocorticoid receptor in distinct neural stem and progenitor populations of the mouse telencephalon in vivo. Brain Research. 1523: 10-27. PMID 23751362 DOI: 10.1016/J.Brainres.2013.06.001  0.404
2013 Defranco DB. Editorial: molecular endocrinology articles in the spotlight for June 2013. Molecular Endocrinology (Baltimore, Md.). 27: 863. PMID 23686424 DOI: 10.1210/Me.2013-1126  0.363
2013 Indyk JA, Candido-Vitto C, Wolf IM, Venkataraman S, Munoz R, Saladino RA, Witchel SF, Defranco DB. Reduced glucocorticoid receptor protein expression in children with critical illness. Hormone Research in Pã¦Diatrics. 79: 169-78. PMID 23548248 DOI: 10.1159/000348290  0.38
2013 DeFranco DB. Editorial: molecular endocrinology articles in the spotlight for April 2013. Molecular Endocrinology (Baltimore, Md.). 27: 557. PMID 23542560 DOI: 10.1210/Me.2013-1064  0.415
2013 Defranco DB. Editorial: molecular endocrinology articles in the spotlight for March 2013. Molecular Endocrinology (Baltimore, Md.). 27: 383. PMID 23439437 DOI: 10.1210/Me.2013-1023  0.38
2013 Grubisha MJ, DeFranco DB. Local endocrine, paracrine and redox signaling networks impact estrogen and androgen crosstalk in the prostate cancer microenvironment. Steroids. 78: 538-41. PMID 23380371 DOI: 10.1016/J.Steroids.2013.01.005  0.773
2012 DeFranco DB. Editorial: Molecular Endocrinology articles in the spotlight for November 2012. Molecular Endocrinology (Baltimore, Md.). 26: 1797. PMID 23103779 DOI: 10.1210/Me.2012-1326  0.315
2012 Defranco DB, Margolis R, McKenna N. Editorial: molecular endocrinology articles in the spotlight for October 2012. Molecular Endocrinology (Baltimore, Md.). 26: 1645. PMID 23023930 DOI: 10.1210/Me.2012-1301  0.497
2012 DeFranco DB. Editorial: molecular endocrinology articles in the spotlight for September 2012. Molecular Endocrinology (Baltimore, Md.). 26: 1481. PMID 22933523 DOI: 10.1210/Me.2012-1246  0.368
2012 Patel VP, Defranco DB, Chu CT. Altered transcription factor trafficking in oxidatively-stressed neuronal cells. Biochimica Et Biophysica Acta. 1822: 1773-82. PMID 22902725 DOI: 10.1016/J.Bbadis.2012.08.002  0.385
2012 DeFranco DB. Editorial: Molecular Endocrinology articles in the spotlight for August 2012. Molecular Endocrinology (Baltimore, Md.). 26: 1251. PMID 22844064 DOI: 10.1210/Me.2012-1209  0.458
2012 Samarasinghe RA, Witchell SF, DeFranco DB. Cooperativity and complementarity: synergies in non-classical and classical glucocorticoid signaling. Cell Cycle (Georgetown, Tex.). 11: 2819-27. PMID 22801547 DOI: 10.4161/Cc.21018  0.412
2012 Sen A, De Castro I, Defranco DB, Deng FM, Melamed J, Kapur P, Raj GV, Rossi R, Hammes SR. Paxillin mediates extranuclear and intranuclear signaling in prostate cancer proliferation. The Journal of Clinical Investigation. 122: 2469-81. PMID 22684108 DOI: 10.1172/Jci62044  0.464
2012 Grubisha MJ, Cifuentes ME, Hammes SR, Defranco DB. A local paracrine and endocrine network involving TGFβ, Cox-2, ROS, and estrogen receptor β influences reactive stromal cell regulation of prostate cancer cell motility. Molecular Endocrinology (Baltimore, Md.). 26: 940-54. PMID 22593181 DOI: 10.1210/Me.2011-1371  0.777
2012 DeFranco DB. Editorial: Molecular Endocrinology articles in the spotlight for May 2012. Molecular Endocrinology (Baltimore, Md.). 26: 715. PMID 22544033 DOI: 10.1210/Me.2012-1097  0.385
2012 DeFranco DB. Editorial: Molecular Endocrinology articles in the spotlight for February 2012. Molecular Endocrinology (Baltimore, Md.). 26: 219. PMID 22282484 DOI: 10.1210/Me.2012-1008  0.428
2012 DeFranco DB. Editorial: molecular endocrinology articles in the spotlight for January 2012. Molecular Endocrinology (Baltimore, Md.). 26: 1. PMID 22210759 DOI: 10.1210/Me.2011-1345  0.313
2011 Samarasinghe RA, Di Maio R, Volonte D, Galbiati F, Lewis M, Romero G, DeFranco DB. Nongenomic glucocorticoid receptor action regulates gap junction intercellular communication and neural progenitor cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 108: 16657-62. PMID 21930911 DOI: 10.1073/Pnas.1102821108  0.424
2011 Stankowski JN, Zeiger SL, Cohen EL, DeFranco DB, Cai J, McLaughlin B. C-terminus of heat shock cognate 70 interacting protein increases following stroke and impairs survival against acute oxidative stress. Antioxidants & Redox Signaling. 14: 1787-801. PMID 20677910 DOI: 10.1089/Ars.2010.3300  0.33
2010 Sen A, O'Malley K, Wang Z, Raj GV, Defranco DB, Hammes SR. Paxillin regulates androgen- and epidermal growth factor-induced MAPK signaling and cell proliferation in prostate cancer cells. The Journal of Biological Chemistry. 285: 28787-95. PMID 20628053 DOI: 10.1074/Jbc.M110.134064  0.513
2010 Caltagarone J, Hamilton RL, Murdoch G, Jing Z, DeFranco DB, Bowser R. Paxillin and hydrogen peroxide-inducible clone 5 expression and distribution in control and Alzheimer disease hippocampi. Journal of Neuropathology and Experimental Neurology. 69: 356-71. PMID 20448481 DOI: 10.1097/Nen.0B013E3181D53D98  0.327
2009 DeFranco DB, McKenna NJ. Signals from NURSA. Molecular Endocrinology (Baltimore, Md.). 23: 1939. PMID 19934347 DOI: 10.1210/Me.2009-0447  0.355
2009 McKenna NJ, DeFranco DB. Molecular endocrinology: A portal for enhanced access and utility of the nuclear receptor signaling atlas (NURSA) web resource. Molecular Endocrinology (Baltimore, Md.). 23: 739. PMID 19470797 DOI: 10.1210/Me.2009-0169  0.32
2009 Nguyen MM, Dincer Z, Wade JR, Alur M, Michalak M, Defranco DB, Wang Z. Cytoplasmic localization of the androgen receptor is independent of calreticulin. Molecular and Cellular Endocrinology. 302: 65-72. PMID 19150386 DOI: 10.1016/J.Mce.2008.12.010  0.418
2008 Gong H, Jarzynka MJ, Cole TJ, Lee JH, Wada T, Zhang B, Gao J, Song WC, DeFranco DB, Cheng SY, Xie W. Glucocorticoids antagonize estrogens by glucocorticoid receptor-mediated activation of estrogen sulfotransferase. Cancer Research. 68: 7386-93. PMID 18794126 DOI: 10.1158/0008-5472.Can-08-1545  0.401
2008 Ho Y, Samarasinghe R, Knoch ME, Lewis M, Aizenman E, DeFranco DB. Selective inhibition of mitogen-activated protein kinase phosphatases by zinc accounts for extracellular signal-regulated kinase 1/2-dependent oxidative neuronal cell death. Molecular Pharmacology. 74: 1141-51. PMID 18635668 DOI: 10.1124/Mol.108.049064  0.733
2008 Wolf IM, Heitzer MD, Grubisha M, DeFranco DB. Coactivators and nuclear receptor transactivation. Journal of Cellular Biochemistry. 104: 1580-6. PMID 18393355 DOI: 10.1002/Jcb.21755  0.774
2007 Heitzer MD, Wolf IM, Sanchez ER, Witchel SF, DeFranco DB. Glucocorticoid receptor physiology. Reviews in Endocrine & Metabolic Disorders. 8: 321-30. PMID 18049904 DOI: 10.1007/S11154-007-9059-8  0.807
2007 Dekelbab BH, Witchel SF, DeFranco DB. TNF-alpha and glucocorticoid receptor interaction in L6 muscle cells: a cooperative downregulation of myosin heavy chain. Steroids. 72: 705-12. PMID 17624386 DOI: 10.1016/J.Steroids.2007.05.007  0.303
2007 Zhang Y, Aizenman E, DeFranco DB, Rosenberg PA. Intracellular zinc release, 12-lipoxygenase activation and MAPK dependent neuronal and oligodendroglial death. Molecular Medicine (Cambridge, Mass.). 13: 350-5. PMID 17622306 DOI: 10.2119/2007-00042.Zhang  0.321
2007 Ho Y, Logue E, Callaway CW, DeFranco DB. Different mechanisms account for extracellular-signal regulated kinase activation in distinct brain regions following global ischemia and reperfusion. Neuroscience. 145: 248-55. PMID 17207579 DOI: 10.1016/J.Neuroscience.2006.11.039  0.715
2007 Heitzer MD, DeFranco DB. Hic-5/ARA55: a prostate stroma-specific AR coactivator. Steroids. 72: 218-20. PMID 17166536 DOI: 10.1016/J.Steroids.2006.11.010  0.792
2006 Lu NZ, Wardell SE, Burnstein KL, Defranco D, Fuller PJ, Giguere V, Hochberg RB, McKay L, Renoir JM, Weigel NL, Wilson EM, McDonnell DP, Cidlowski JA. International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors. Pharmacological Reviews. 58: 782-97. PMID 17132855 DOI: 10.1124/Pr.58.4.9  0.407
2006 Witchel SF, DeFranco DB. Mechanisms of disease: regulation of glucocorticoid and receptor levels--impact on the metabolic syndrome. Nature Clinical Practice. Endocrinology & Metabolism. 2: 621-31. PMID 17082809 DOI: 10.1038/Ncpendmet0323  0.443
2006 Rasar M, DeFranco DB, Hammes SR. Paxillin regulates steroid-triggered meiotic resumption in oocytes by enhancing an all-or-none positive feedback kinase loop. The Journal of Biological Chemistry. 281: 39455-64. PMID 17065147 DOI: 10.1074/Jbc.M608959200  0.377
2006 Heitzer MD, DeFranco DB. Hic-5, an adaptor-like nuclear receptor coactivator. Nuclear Receptor Signaling. 4: e019. PMID 16862225 DOI: 10.1621/Nrs.04019  0.792
2006 Heitzer MD, DeFranco DB. Hic-5/ARA55, a LIM domain-containing nuclear receptor coactivator expressed in prostate stromal cells. Cancer Research. 66: 7326-33. PMID 16849583 DOI: 10.1158/0008-5472.Can-05-2379  0.804
2006 Jiang H, Poirier MA, Liang Y, Pei Z, Weiskittel CE, Smith WW, DeFranco DB, Ross CA. Depletion of CBP is directly linked with cellular toxicity caused by mutant huntingtin. Neurobiology of Disease. 23: 543-51. PMID 16766198 DOI: 10.1016/J.Nbd.2006.04.011  0.708
2006 Luo Y, DeFranco DB. Opposing roles for ERK1/2 in neuronal oxidative toxicity: distinct mechanisms of ERK1/2 action at early versus late phases of oxidative stress. The Journal of Biological Chemistry. 281: 16436-42. PMID 16621802 DOI: 10.1074/Jbc.M512430200  0.354
2006 Heitzer MD, DeFranco DB. Mechanism of action of Hic-5/androgen receptor activator 55, a LIM domain-containing nuclear receptor coactivator. Molecular Endocrinology (Baltimore, Md.). 20: 56-64. PMID 16141357 DOI: 10.1210/Me.2005-0065  0.807
2005 D'Cruz BJ, Logue ES, Falke E, DeFranco DB, Callaway CW. Hypothermia and ERK activation after cardiac arrest. Brain Research. 1064: 108-18. PMID 16289484 DOI: 10.1016/J.Brainres.2005.09.052  0.301
2005 Wang X, DeFranco DB. Alternative effects of the ubiquitin-proteasome pathway on glucocorticoid receptor down-regulation and transactivation are mediated by CHIP, an E3 ligase. Molecular Endocrinology (Baltimore, Md.). 19: 1474-82. PMID 15761032 DOI: 10.1210/Me.2004-0383  0.432
2005 Levinthal DJ, Defranco DB. Reversible oxidation of ERK-directed protein phosphatases drives oxidative toxicity in neurons. The Journal of Biological Chemistry. 280: 5875-83. PMID 15579467 DOI: 10.1074/Jbc.M410771200  0.673
2004 Elbi C, Walker DA, Lewis M, Romero G, Sullivan WP, Toft DO, Hager GL, DeFranco DB. A novel in situ assay for the identification and characterization of soluble nuclear mobility factors. Science's Stke : Signal Transduction Knowledge Environment. 2004: pl10. PMID 15213337 DOI: 10.1126/Stke.2382004Pl10  0.339
2004 Guerrero-Santoro J, Yang L, Stallcup MR, DeFranco DB. Distinct LIM domains of Hic-5/ARA55 are required for nuclear matrix targeting and glucocorticoid receptor binding and coactivation. Journal of Cellular Biochemistry. 92: 810-9. PMID 15211577 DOI: 10.1002/Jcb.20109  0.376
2004 DeFranco DB, Ho L, Falke E, Callaway CW. Small molecule activators of the heat shock response and neuroprotection from stroke. Current Atherosclerosis Reports. 6: 295-300. PMID 15191704 DOI: 10.1007/S11883-004-0061-2  0.342
2004 Pratt WB, Galigniana MD, Harrell JM, DeFranco DB. Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement. Cellular Signalling. 16: 857-72. PMID 15157665 DOI: 10.1016/J.Cellsig.2004.02.004  0.361
2004 Chu CT, Levinthal DJ, Kulich SM, Chalovich EM, DeFranco DB. Oxidative neuronal injury. The dark side of ERK1/2. European Journal of Biochemistry / Febs. 271: 2060-6. PMID 15153095 DOI: 10.1111/J.1432-1033.2004.04132.X  0.685
2004 Pongrac JL, Gibbs RB, Defranco DB. Estrogen-mediated regulation of cholinergic expression in basal forebrain neurons requires extracellular-signal-regulated kinase activity. Neuroscience. 124: 809-16. PMID 15026121 DOI: 10.1016/J.Neuroscience.2004.01.013  0.381
2004 Elbi C, Walker DA, Romero G, Sullivan WP, Toft DO, Hager GL, DeFranco DB. Molecular chaperones function as steroid receptor nuclear mobility factors. Proceedings of the National Academy of Sciences of the United States of America. 101: 2876-81. PMID 14978266 DOI: 10.1073/Pnas.0400116101  0.45
2004 Levinthal DJ, DeFranco DB. Transient phosphatidylinositol 3-kinase inhibition protects immature primary cortical neurons from oxidative toxicity via suppression of extracellular signal-regulated kinase activation. The Journal of Biological Chemistry. 279: 11206-13. PMID 14715649 DOI: 10.1074/Jbc.M314261200  0.676
2003 Kasai M, Guerrero-Santoro J, Friedman R, Leman ES, Getzenberg RH, DeFranco DB. The Group 3 LIM domain protein paxillin potentiates androgen receptor transactivation in prostate cancer cell lines. Cancer Research. 63: 4927-35. PMID 12941817  0.377
2003 Jiang H, Nucifora FC, Ross CA, DeFranco DB. Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein. Human Molecular Genetics. 12: 1-12. PMID 12490527 DOI: 10.1093/Hmg/Ddg002  0.723
2002 Wang X, Pongrac JL, DeFranco DB. Glucocorticoid receptors in hippocampal neurons that do not engage proteasomes escape from hormone-dependent down-regulation but maintain transactivation activity. Molecular Endocrinology (Baltimore, Md.). 16: 1987-98. PMID 12198236 DOI: 10.1210/Me.2001-0287  0.473
2002 D'Cruz BJ, Fertig KC, Filiano AJ, Hicks SD, DeFranco DB, Callaway CW. Hypothermic reperfusion after cardiac arrest augments brain-derived neurotrophic factor activation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 843-51. PMID 12142569 DOI: 10.1097/00004647-200207000-00009  0.301
2002 DeFranco DB. Navigating steroid hormone receptors through the nuclear compartment. Molecular Endocrinology (Baltimore, Md.). 16: 1449-55. PMID 12089341 DOI: 10.1210/Mend.16.7.0880  0.478
2002 Deroo BJ, Rentsch C, Sampath S, Young J, DeFranco DB, Archer TK. Proteasomal inhibition enhances glucocorticoid receptor transactivation and alters its subnuclear trafficking. Molecular and Cellular Biology. 22: 4113-23. PMID 12024025 DOI: 10.1128/Mcb.22.12.4113-4123.2002  0.482
2002 DeFranco DB. Nuclear export: DNA-binding domains find a surprising partner. Current Biology : Cb. 11: R1036-7. PMID 11747843 DOI: 10.1016/S0960-9822(01)00619-4  0.38
2002 Stanciu M, DeFranco DB. Prolonged nuclear retention of activated extracellular signal-regulated protein kinase promotes cell death generated by oxidative toxicity or proteasome inhibition in a neuronal cell line. The Journal of Biological Chemistry. 277: 4010-7. PMID 11726647 DOI: 10.1074/Jbc.M104479200  0.379
2000 DeFranco DB, Csermely P. Steroid receptor and molecular chaperone encounters in the nucleus. Science's Stke : Signal Transduction Knowledge Environment. 2000: pe1. PMID 11752599 DOI: 10.1126/Stke.2000.42.Pe1  0.429
2000 Hicks SD, Parmele KT, DeFranco DB, Klann E, Callaway CW. Hypothermia differentially increases extracellular signal-regulated kinase and stress-activated protein kinase/c-Jun terminal kinase activation in the hippocampus during reperfusion after asphyxial cardiac arrest. Neuroscience. 98: 677-85. PMID 10891611 DOI: 10.1016/S0306-4522(00)00169-X  0.327
2000 Yang L, Guerrero J, Hong H, DeFranco DB, Stallcup MR. Interaction of the τ2 transcriptional activation domain of glucocorticoid receptor with a novel steroid receptor coactivator, Hic-5, which localizes to both focal adhesions and the nuclear matrix Molecular Biology of the Cell. 11: 2007-2018. PMID 10848625 DOI: 10.1091/Mbc.11.6.2007  0.483
2000 Stanciu M, Wang Y, Kentor R, Burke N, Watkins S, Kress G, Reynolds I, Klann E, Angiolieri MR, Johnson JW, DeFranco DB. Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures. The Journal of Biological Chemistry. 275: 12200-6. PMID 10766856 DOI: 10.1074/Jbc.275.16.12200  0.367
2000 Defranco DB. Role of molecular chaperones in subnuclear trafficking of glucocorticoid receptors. Kidney International. 57: 1241-9. PMID 10760049 DOI: 10.1046/J.1523-1755.2000.00957.X  0.456
2000 Liu J, DeFranco DB. Protracted nuclear export of glucocorticoid receptor limits its turnover and does not require the exportin 1/CRM1-directed nuclear export pathway. Molecular Endocrinology (Baltimore, Md.). 14: 40-51. PMID 10628746 DOI: 10.1210/Mend.14.1.0398  0.461
2000 Liu J, Xiao N, DeFranco DB. Use of digitonin-permeabilized cells in studies of steroid receptor subnuclear trafficking. Methods (San Diego, Calif.). 19: 403-9. PMID 10579935 DOI: 10.1006/Meth.1999.0876  0.449
2000 DeFranco DB, Guerrero J. Nuclear Matrix Targeting of Steroid Receptors: Specific Signal Sequences and Acceptor Proteins Critical Reviews™ in Eukaryotic Gene Expression. 10: 6. DOI: 10.1615/Critreveukargeneexpr.V10.I1.60  0.436
1999 Chandran UR, DeFranco DB. Regulation of gonadotropin-releasing hormone gene transcription. Behavioural Brain Research. 105: 29-36. PMID 10553688 DOI: 10.1016/S0166-4328(99)00080-7  0.4
1999 Galigniana MD, Housley PR, DeFranco DB, Pratt WB. Inhibition of glucocorticoid receptor nucleocytoplasmic shuttling by okadaic acid requires intact cytoskeleton Journal of Biological Chemistry. 274: 16222-16227. PMID 10347177 DOI: 10.1074/Jbc.274.23.16222  0.305
1999 DeFranco DB. Regulation of steroid receptor subcellular trafficking. Cell Biochemistry and Biophysics. 30: 1-24. PMID 10099820 DOI: 10.1007/Bf02737882  0.472
1999 Liu J, DeFranco DB. Chromatin recycling of glucocorticoid receptors: implications for multiple roles of heat shock protein 90. Molecular Endocrinology (Baltimore, Md.). 13: 355-65. PMID 10076993 DOI: 10.1210/Mend.13.3.0258  0.416
1999 Xiao N, Callaway CW, Lipinski CA, Hicks SD, DeFranco DB. Geldanamycin provides posttreatment protection against glutamate-induced oxidative toxicity in a mouse hippocampal cell line. Journal of Neurochemistry. 72: 95-101. PMID 9886059 DOI: 10.1046/J.1471-4159.1999.0720095.X  0.339
1998 Tang Y, Getzenberg RH, Vietmeier BN, Stallcup MR, Eggert M, Renkawitz R, DeFranco DB. The DNA-Binding and τ2 Transactivation Domains of the Rat Glucocorticoid Receptor Constitute a Nuclear Matrix-Targeting Signal Molecular Endocrinology. 12: 1420-1431. PMID 9731709 DOI: 10.1210/Mend.12.9.0169  0.376
1998 DeFranco DB, Ramakrishnan C, Tang Y. Molecular chaperones and subcellular trafficking of steroid receptors. The Journal of Steroid Biochemistry and Molecular Biology. 65: 51-8. PMID 9699857 DOI: 10.1016/S0960-0760(97)00177-5  0.413
1997 Attardi B, Tsujii T, Friedman R, Zeng Z, Roberts JL, Dellovade T, Pfaff DW, Chandran UR, Sullivan MW, DeFranco DB. Glucocorticoid repression of gonadotropin-releasing hormone gene expression and secretion in morphologically distinct subpopulations of GT1-7 cells. Molecular and Cellular Endocrinology. 131: 241-55. PMID 9296383 DOI: 10.1016/S0303-7207(97)00102-0  0.352
1997 Xiao N, DeFranco DB. Overexpression of unliganded steroid receptors activates endogenous heat shock factor Molecular Endocrinology. 11: 1365-1374. PMID 9259326 DOI: 10.1210/Mend.11.9.9976  0.455
1997 Tang Y, Ramakrishnan C, Thomas J, DeFranco DB. A role for HDJ-2/HSDJ in correcting subnuclear trafficking, transactivation, and transrepression defects of a glucocorticoid receptor zinc finger mutant. Molecular Biology of the Cell. 8: 795-809. PMID 9168467 DOI: 10.1091/Mbc.8.5.795  0.389
1997 Yang J, Liu J, DeFranco DB. Subnuclear trafficking of glucocorticoid receptors in vitro: chromatin recycling and nuclear export. The Journal of Cell Biology. 137: 523-38. PMID 9151662 DOI: 10.1083/Jcb.137.3.523  0.422
1996 Yang J, DeFranco DB. Assessment of glucocorticoid receptor-heat shock protein 90 interactions in vivo during nucleocytoplasmic trafficking. Molecular Endocrinology (Baltimore, Md.). 10: 3-13. PMID 8838140 DOI: 10.1210/Mend.10.1.8838140  0.42
1996 Chandran UR, Attardi B, Friedman R, Zheng Zw, Roberts JL, DeFranco DB. Glucocorticoid repression of the mouse gonadotropin-releasing hormone gene is mediated by promoter elements that are recognized by heteromeric complexes containing glucocorticoid receptor. The Journal of Biological Chemistry. 271: 20412-20. PMID 8702778 DOI: 10.1074/Jbc.271.34.20412  0.4
1996 Tang Y, DeFranco DB. ATP-dependent release of glucocorticoid receptors from the nuclear matrix. Molecular and Cellular Biology. 16: 1989-2001. PMID 8628265 DOI: 10.1128/Mcb.16.5.1989  0.434
1995 Hsu SC, DeFranco DB. Selectivity of cell cycle regulation of glucocorticoid receptor function Journal of Biological Chemistry. 270: 3359-3364. PMID 7852422 DOI: 10.1074/Jbc.270.7.3359  0.459
1995 Nordeen SK, Bona BJ, Beck CA, Edwards DP, Borror KC, DeFranco DB. The two faces of a steroid antagonist: when an antagonist isn't. Steroids. 60: 97-104. PMID 7792825 DOI: 10.1016/0039-128X(94)00001-S  0.457
1995 Borror KC, Garabedian MJ, DeFranco DB. Glucocorticoid receptor phosphorylation in v-mos-transformed cells Steroids. 60: 375-382. PMID 7570710 DOI: 10.1016/0039-128X(94)00068-N  0.392
1995 Defranco DB, Madan AP, Tang Y, Chandran UR, Xiao N, Yang J. Nucleocytoplasmic shuttling of steroid receptors. Vitamins and Hormones. 51: 315-38. PMID 7483326 DOI: 10.1016/S0083-6729(08)61043-2  0.465
1994 Chandran UR, Attardi B, Friedman R, Dong KW, Roberts JL, DeFranco DB. Glucocorticoid receptor-mediated repression of gonadotropin-releasing hormone promoter activity in GT1 hypothalamic cell lines. Endocrinology. 134: 1467-74. PMID 8119188 DOI: 10.1210/endo.134.3.8119188  0.316
1994 Yang J, DeFranco DB. Differential roles of heat shock protein 70 in the in vitro nuclear import of glucocorticoid receptor and simian virus 40 large tumor antigen. Molecular and Cellular Biology. 14: 5088-98. PMID 8035791 DOI: 10.1128/Mcb.14.8.5088  0.455
1993 Madan AP, DeFranco DB. Bidirectional transport of glucocorticoid receptors across the nuclear envelope. Proceedings of the National Academy of Sciences of the United States of America. 90: 3588-92. PMID 8386376 DOI: 10.1073/Pnas.90.8.3588  0.405
1992 Gluecksohn-Waelsch S, DeFranco D. Lethal chromosomal deletions in the mouse, a model system for the study of development and regulation of postnatal gene expression. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 13: 557-61. PMID 1772410 DOI: 10.1002/Bies.950131102  0.334
1992 Chandran UR, DeFranco DB. Internuclear migration of chicken progesterone receptor, but not simian virus-40 large tumor antigen, in transient heterokaryons. Molecular Endocrinology (Baltimore, Md.). 6: 837-44. PMID 1603089 DOI: 10.1210/Mend.6.5.1603089  0.417
1992 Somers JP, DeFranco DB. Effects of okadaic acid, a protein phosphatase inhibitor, on glucocorticoid receptor-mediated enhancement Molecular Endocrinology. 6: 26-34. PMID 1310797 DOI: 10.1210/Mend.6.1.1310797  0.473
1992 Hsu S, Qi M, DeFranco D. Cell cycle regulation of glucocorticoid receptor function. The Embo Journal. 11: 3457-3468. DOI: 10.1002/J.1460-2075.1992.Tb05425.X  0.395
1991 DeFranco D, Bali D, Torres R, DePinho RA, Erickson RP, Gluecksohn-Waelsch S. The glucocorticoid hormone signal transduction pathway in mice homozygous for chromosomal deletions causing failure of cell type-specific inducible gene expression. Proceedings of the National Academy of Sciences of the United States of America. 88: 5607-10. PMID 2062840 DOI: 10.1073/Pnas.88.13.5607  0.398
1991 DeFranco DB, Qi M, Borror KC, Garabedian MJ, Brautigan DL. Protein phosphatase types 1 and/or 2A regulate nucleocytoplasmic shuttling of glucocorticoid receptors Molecular Endocrinology. 5: 1215-1228. PMID 1663212 DOI: 10.1210/Mend-5-9-1215  0.371
1990 Qi M, Stasenko LJ, DeFranco DB. Recycling and desensitization of glucocorticoid receptors in v-mos transformed cells depend on the ability of nuclear receptors to modulate gene expression. Molecular Endocrinology (Baltimore, Md.). 4: 455-64. PMID 2160602 DOI: 10.1210/Mend-4-3-455  0.423
1990 Nebes VL, DeFranco D, Morris SM. Differential induction of transcription for glucocorticoid-responsive genes in cultured rat hepatocytes Biochemical and Biophysical Research Communications. 166: 133-138. PMID 1967935 DOI: 10.1016/0006-291X(90)91921-E  0.325
1989 Hamilton BJ, DeFranco D. Glucocorticoid and cAMP induction mechanisms are differentially affected by the p85gag-mos oncoprotein. Proceedings of the National Academy of Sciences of the United States of America. 86: 597-601. PMID 2536170 DOI: 10.1073/Pnas.86.2.597  0.34
1989 Qi M, Hamilton BJ, DeFranco D. v-mos oncoproteins affect the nuclear retention and reutilization of glucocorticoid receptors. Molecular Endocrinology (Baltimore, Md.). 3: 1279-88. PMID 2528691 DOI: 10.1210/Mend-3-8-1279  0.438
1987 DeFranco D, Yamamoto KR. Two different factors act separately or together to specify functionally distinct activities at a single transcriptional enhancer. Molecular and Cellular Biology. 6: 993-1001. PMID 3023887 DOI: 10.1128/MCB.6.4.993  0.302
1983 Payvar F, DeFranco D, Firestone GL, Edgar B, Wrange O, Okret S, Gustafsson JA, Yamamoto KR. Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region. Cell. 35: 381-92. PMID 6317184 DOI: 10.1016/0092-8674(83)90171-X  0.367
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