| Year |
Citation |
Score |
| 2020 |
Shukla K, Singh N, Lewis JE, Tsang AW, Boothman DA, Kemp ML, Furdui CM. MTHFD2 Blockade Enhances the Efficacy of β-Lapachone Chemotherapy With Ionizing Radiation in Head and Neck Squamous Cell Cancer. Frontiers in Oncology. 10: 536377. PMID 33262939 DOI: 10.3389/fonc.2020.536377 |
0.313 |
|
| 2020 |
Starcher CL, Pay SL, Singh N, Yeh IJ, Bhandare SB, Su X, Huang X, Bey EA, Motea EA, Boothman DA. Targeting Base Excision Repair in Cancer: NQO1-Bioactivatable Drugs Improve Tumor Selectivity and Reduce Treatment Toxicity Through Radiosensitization of Human Cancer. Frontiers in Oncology. 10: 1575. PMID 32974194 DOI: 10.3389/Fonc.2020.01575 |
0.441 |
|
| 2020 |
Torrente L, Prieto-Farigua N, Falzone A, Elkins CM, Boothman DA, Haura EB, DeNicola GM. Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone. Redox Biology. 30: 101440. PMID 32007910 DOI: 10.1016/J.Redox.2020.101440 |
0.386 |
|
| 2020 |
Hashemi-Sadraei N, Adra N, Kessler KA, Idrees MT, Einhorn L, Boothman DA. NAD(P)H: Quinone oxidoreductase (NQO1) and catalase expression in nonseminomatous germ cell tumors. Journal of Clinical Oncology. 38: 413-413. DOI: 10.1200/Jco.2020.38.6_Suppl.413 |
0.32 |
|
| 2019 |
Li X, Liu Z, Zhang A, Han C, Shen A, Jiang L, Boothman DA, Qiao J, Wang Y, Huang X, Fu YX. NQO1 targeting prodrug triggers innate sensing to overcome checkpoint blockade resistance. Nature Communications. 10: 3251. PMID 31324798 DOI: 10.1038/S41467-019-11238-1 |
0.359 |
|
| 2019 |
Motea EA, Huang X, Singh N, Kilgore JA, Williams NS, Xie XJ, Gerber DE, Beg M, Bey EA, Boothman DA. NQO1-dependent, tumor-selective radiosensitization of non-small cell lung cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30617135 DOI: 10.1158/1078-0432.Ccr-18-2560 |
0.385 |
|
| 2018 |
Gerber DE, Beg MS, Fattah F, Frankel AE, Fatunde O, Arriaga Y, Dowell JE, Bisen A, Leff RD, Meek CC, Putnam WC, Kallem RR, Subramaniyan I, Dong Y, Bolluyt J, ... ... Boothman DA, et al. Phase 1 study of ARQ 761, a β-lapachone analogue that promotes NQO1-mediated programmed cancer cell necrosis. British Journal of Cancer. PMID 30318513 DOI: 10.1038/S41416-018-0278-4 |
0.371 |
|
| 2018 |
Motea EA, Fattah FJ, Xiao L, Girard L, Rommel A, Morales JC, Patidar P, Zhou Y, Porter A, Xie Y, Minna JD, Boothman DA. Kub5-Hera RPRD1B deficiency promotes "BRCAness" and vulnerability to PARP inhibition in BRCA-proficient Breast Cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30108102 DOI: 10.1158/1078-0432.Ccr-17-1118 |
0.388 |
|
| 2018 |
Kahanda D, Singh N, Boothman DA, Slinker JD. Following anticancer drug activity in cell lysates with DNA devices. Biosensors & Bioelectronics. 119: 1-9. PMID 30098460 DOI: 10.1016/J.Bios.2018.07.059 |
0.471 |
|
| 2018 |
Lewis J, Furdui C, Boothman D, Kemp M. Genome-scale metabolic modeling identifies novel targets of redox metabolism in radiation-resistant tumors Free Radical Biology and Medicine. 128: S88. DOI: 10.1016/J.Freeradbiomed.2018.10.203 |
0.34 |
|
| 2017 |
Chen X, Mims J, Huang X, Singh N, Motea EA, Planchon SM, Beg M, Tsang AW, Porosnicu M, Kemp ML, Boothman DA, Furdui C. Modulators of Redox Metabolism in Head and Neck Cancer. Antioxidants & Redox Signaling. PMID 29113454 DOI: 10.1089/Ars.2017.7423 |
0.318 |
|
| 2017 |
Silvers MA, Deja S, Singh N, Egnatchik RA, Sudderth J, Luo X, Beg MS, Burgess SC, DeBerardinis RJ, Boothman DA, Merritt ME. The NQO1 bioactivatable drug, β-Lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism. The Journal of Biological Chemistry. PMID 28916726 DOI: 10.1074/Jbc.M117.813923 |
0.427 |
|
| 2017 |
Beg MS, Huang X, Silvers MA, Gerber DE, Bolluyt J, Sarode V, Fattah F, Deberardinis RJ, Merritt ME, Xie XJ, Leff R, Laheru D, Boothman DA. Using a novel NQO1 bioactivatable drug, beta-lapachone (ARQ761), to enhance chemotherapeutic effects by metabolic modulation in pancreatic cancer. Journal of Surgical Oncology. PMID 28346693 DOI: 10.1002/Jso.24624 |
0.44 |
|
| 2017 |
Gerber DE, Bisen AK, Beg MS, Frankel AE, Fatunde O, Fattah F, Arriaga YE, Dowell J, Meek C, Bolluyt JD, Sarode V, Luo X, Xie Y, Schwartz BE, Boothman DA, et al. Phase 1 study of ARQ 761, a β-lapachone analog that promotes NQO1-mediated programmed cancer cell necrosis. Journal of Clinical Oncology. 35: 2517-2517. DOI: 10.1200/Jco.2017.35.15_Suppl.2517 |
0.38 |
|
| 2016 |
Zhou Y, Dong Y, Huang G, Wang Y, Huang X, Zhang F, Boothman DA, Gao J, Liang W. Lysosome-oriented, dual-stage pH-responsive polymeric micelles for β-Lapachone delivery. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 4: 7429-7440. PMID 28580145 DOI: 10.1039/C6Tb02049F |
0.312 |
|
| 2016 |
Huang X, Motea EA, Moore ZR, Yao J, Dong Y, Chakrabarti G, Kilgore JA, Silvers MA, Patidar PL, Cholka A, Fattah F, Cha Y, Anderson GG, Kusko R, Peyton M, ... ... Boothman DA, et al. Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors. Cancer Cell. 30: 940-952. PMID 27960087 DOI: 10.1016/J.Ccell.2016.11.006 |
0.485 |
|
| 2016 |
Morales JC, Richard P, Patidar PL, Motea EA, Dang TT, Manley JL, Boothman DA. XRN2 Links Transcription Termination to DNA Damage and Replication Stress. Plos Genetics. 12: e1006107. PMID 27437695 DOI: 10.1371/Journal.Pgen.1006107 |
0.342 |
|
| 2016 |
da Cruz EH, Silvers MA, Jardim GA, Resende JM, Cavalcanti BC, Bomfim IS, Pessoa C, de Simone CA, Botteselle GV, Braga AL, Nair DK, Namboothiri IN, Boothman DA, da Silva Júnior EN. Synthesis and antitumor activity of selenium-containing quinone-based triazoles possessing two redox centres, and their mechanistic insights. European Journal of Medicinal Chemistry. 122: 1-16. PMID 27341379 DOI: 10.1016/J.Ejmech.2016.06.019 |
0.364 |
|
| 2016 |
Tang KJ, Constanzo J, Venkateswaran N, Melegari M, Ilcheva M, Morales JC, Skoulidis F, Heymach JV, Boothman DA, Scaglioni PP. Focal Adhesion Kinase regulates the DNA damage response and its inhibition radiosensitizes mutant KRAS lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27220963 DOI: 10.1158/1078-0432.Ccr-15-2603 |
0.375 |
|
| 2016 |
Li LS, Reddy S, Lin ZH, Liu S, Park H, Chun SG, Bornmann WG, Thibodeaux J, Yan J, Chakrabarti G, Xie XJ, Sumer BD, Boothman DA, Yordy JS. NQO1-mediated tumor-selective lethality and radiosensitization for head and neck cancer. Molecular Cancer Therapeutics. PMID 27196777 DOI: 10.1158/1535-7163.Mct-15-0765 |
0.449 |
|
| 2016 |
Kahanda D, Chakrabarti G, Mcwilliams MA, Boothman DA, Slinker JD. Using DNA devices to track anticancer drug activity. Biosensors & Bioelectronics. 80: 647-653. PMID 26901461 DOI: 10.1016/J.Bios.2016.02.026 |
0.425 |
|
| 2016 |
Patidar PL, Motea EA, Fattah FJ, Zhou Y, Morales JC, Xie Y, Garner HR, Boothman DA. The Kub5-Hera/RPRD1B interactome: a novel role in preserving genetic stability by regulating DNA mismatch repair. Nucleic Acids Research. PMID 26819409 DOI: 10.1093/Nar/Gkv1492 |
0.35 |
|
| 2016 |
Madajewski B, Boatman MA, Chakrabarti G, Boothman DA, Bey EA. Depleting Tumor-NQO1 Potentiates Anoikis and Inhibits Growth of NSCLC. Molecular Cancer Research : McR. 14: 14-25. PMID 26553038 DOI: 10.1158/1541-7786.Mcr-15-0207-T |
0.381 |
|
| 2016 |
Boothman DA. Leveraging an NQO1 bioactivatable drug for tumor-selective use of poly (ADP-ribose) polymerase (PARP) inhibitors Journal of Postgenomics Drug & Biomarker Development. 6. DOI: 10.4172/2153-0769.C1.033 |
0.306 |
|
| 2016 |
Meade JC, Moore ZR, Stuart SH, Cholka A, Boriack RL, Xu J, Erdreich-Epstein A, Rakheja D, Boothman DA, Amatruda JF, Laetsch TW. Abstract B39: NQO1 as a therapeutic target for atypical teratoid/ rhabdoid tumor Cancer Research. 76. DOI: 10.1158/1538-7445.Pedca15-B39 |
0.415 |
|
| 2016 |
Topalovski M, Wang M, Moore Z, Boothman D, Brekken R. Abstract 5093: Fibulin-5 supports pancreatic tumor growth through inhibition of integrin-induced ROS Cancer Research. 76: 5093-5093. DOI: 10.1158/1538-7445.Am2016-5093 |
0.313 |
|
| 2015 |
Jiang L, Deberardinis R, Boothman DA. The cancer cell 'energy grid': TGF-β1 signaling coordinates metabolism for migration. Molecular & Cellular Oncology. 2: e981994. PMID 27308459 DOI: 10.4161/23723556.2014.981994 |
0.39 |
|
| 2015 |
Chakrabarti G, Silvers MA, Ilcheva M, Liu Y, Moore ZR, Luo X, Gao J, Anderson G, Liu L, Sarode V, Gerber DE, Burma S, DeBerardinis RJ, Gerson SL, Boothman DA. Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone. Scientific Reports. 5: 17066. PMID 26602448 DOI: 10.1038/Srep17066 |
0.494 |
|
| 2015 |
Wang M, Topalovski M, Toombs JE, Wright CM, Moore ZR, Boothman DA, Yanagisawa H, Wang H, Witkiewicz A, Castrillon DH, Brekken RA. Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer. Cancer Research. PMID 26577699 DOI: 10.1158/0008-5472.Can-15-0744 |
0.374 |
|
| 2015 |
Gerber DE, Boothman DA, Fattah FJ, Dong Y, Zhu H, Skelton RA, Priddy LL, Vo P, Dowell JE, Sarode V, Leff R, Meek C, Xie Y, Schiller JH. Phase 1 study of romidepsin plus erlotinib in advanced non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). PMID 26474959 DOI: 10.1016/J.Lungcan.2015.10.008 |
0.337 |
|
| 2015 |
Chakrabarti G, Moore ZR, Luo X, Ilcheva M, Ali A, Padanad M, Zhou Y, Xie Y, Burma S, Scaglioni PP, Cantley LC, DeBerardinis RJ, Kimmelman AC, Lyssiotis CA, Boothman DA. Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone. Cancer & Metabolism. 3: 12. PMID 26462257 DOI: 10.1186/S40170-015-0137-1 |
0.324 |
|
| 2015 |
Ma X, Moore ZR, Huang G, Huang X, Boothman DA, Gao J. Nanotechnology-enabled delivery of NQO1 bioactivatable drugs. Journal of Drug Targeting. 23: 672-80. PMID 26453163 DOI: 10.3109/1061186X.2015.1073296 |
0.369 |
|
| 2015 |
Chakrabarti G, Gerber DE, Boothman DA. Expanding antitumor therapeutic windows by targeting cancer-specific nicotinamide adenine dinucleotide phosphate-biogenesis pathways. Clinical Pharmacology : Advances and Applications. 7: 57-68. PMID 25870517 DOI: 10.2147/CPAA.S79760 |
0.352 |
|
| 2015 |
Moore Z, Chakrabarti G, Luo X, Ali A, Hu Z, Fattah FJ, Vemireddy R, DeBerardinis RJ, Brekken RA, Boothman DA. NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone. Cell Death & Disease. 6: e1599. PMID 25590809 DOI: 10.1038/Cddis.2014.564 |
0.489 |
|
| 2015 |
Ma X, Huang X, Moore Z, Huang G, Kilgore JA, Wang Y, Hammer S, Williams NS, Boothman DA, Gao J. Esterase-activatable β-lapachone prodrug micelles for NQO1-targeted lung cancer therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 200: 201-11. PMID 25542645 DOI: 10.1016/J.Jconrel.2014.12.027 |
0.367 |
|
| 2015 |
Jiang L, Xiao L, Sugiura H, Huang X, Ali A, Kuro-o M, Deberardinis RJ, Boothman DA. Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition. Oncogene. 34: 3908-3916. PMID 25284588 DOI: 10.1038/Onc.2014.321 |
0.383 |
|
| 2015 |
Ilcheva M, Cao L, Burma S, Boothman D. Abstract P6-02-02: Exploiting Isobutyl-deoxynyboquinone-induced DNA damage responses and metabolic changes for breast cancer therapy Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P6-02-02 |
0.489 |
|
| 2014 |
Luo X, Suzuki M, Ghandhi SA, Amundson SA, Boothman DA. ATM regulates insulin-like growth factor 1-secretory clusterin (IGF-1-sCLU) expression that protects cells against senescence. Plos One. 9: e99983. PMID 24937130 DOI: 10.1371/Journal.Pone.0099983 |
0.421 |
|
| 2014 |
Fattah FJ, Hara K, Fattah KR, Yang C, Wu N, Warrington R, Chen DJ, Zhou P, Boothman DA, Yu H. The transcription factor TFII-I promotes DNA translesion synthesis and genomic stability. Plos Genetics. 10: e1004419. PMID 24922507 DOI: 10.1371/Journal.Pgen.1004419 |
0.349 |
|
| 2014 |
Morales JC, Richard P, Rommel A, Fattah FJ, Motea EA, Patidar PL, Xiao L, Leskov K, Wu SY, Hittelman WN, Chiang CM, Manley JL, Boothman DA. Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair. Nucleic Acids Research. 42: 4996-5006. PMID 24589584 DOI: 10.1093/Nar/Gku160 |
0.333 |
|
| 2014 |
Morales J, Li L, Fattah FJ, Dong Y, Bey EA, Patel M, Gao J, Boothman DA. Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases. Critical Reviews in Eukaryotic Gene Expression. 24: 15-28. PMID 24579667 DOI: 10.1615/Critreveukaryotgeneexpr.2013006875 |
0.478 |
|
| 2014 |
Cao L, Li LS, Spruell C, Xiao L, Chakrabarti G, Bey EA, Reinicke KE, Srougi MC, Moore Z, Dong Y, Vo P, Kabbani W, Yang CR, Wang X, Fattah F, ... ... Boothman DA, et al. Tumor-selective, futile redox cycle-induced bystander effects elicited by NQO1 bioactivatable radiosensitizing drugs in triple-negative breast cancers. Antioxidants & Redox Signaling. 21: 237-50. PMID 24512128 DOI: 10.1089/Ars.2013.5462 |
0.754 |
|
| 2014 |
Huang X, Moore Z, Luo X, Chakrabarti G, Ilcheva M, Brekken R, Burma S, Gao J, Deberardinis R, Bornmann W, Hergenrother P, Boothman DA. Abstract 787: DNA repair and metabolism inhibitors are tumor-selective when combined with NQO1 bioactivatable drugs for therapy against pancreatic and nonsmall cell lung cancers Cancer Research. 74: 787-787. DOI: 10.1158/1538-7445.Am2014-787 |
0.468 |
|
| 2014 |
Moore Z, Boothman DA. Abstract 1760: Tumor-specific targeting of the NAD metabolome with β-lapachone and NamPT inhibition Cancer Research. 74: 1760-1760. DOI: 10.1158/1538-7445.Am2014-1760 |
0.47 |
|
| 2014 |
Chakrabarti G, Boothman DA. Abstract 1679: Inhibiting KRAS-reprogrammed glutamine metabolism sensitizes pancreatic cancer to NQO1-bioactivatable drugs Cancer Research. 74: 1679-1679. DOI: 10.1158/1538-7445.Am2014-1679 |
0.46 |
|
| 2013 |
Puliyappadamba VT, Chakraborty S, Chauncey SS, Li L, Hatanpaa KJ, Mickey B, Noorani S, Shu HK, Burma S, Boothman DA, Habib AA. Opposing effect of EGFRWT on EGFRvIII-mediated NF-κB activation with RIP1 as a cell death switch. Cell Reports. 4: 764-75. PMID 23972990 DOI: 10.1016/J.Celrep.2013.07.025 |
0.337 |
|
| 2013 |
Chakraborty S, Li L, Tang H, Xie Y, Puliyappadamba VT, Raisanen J, Burma S, Boothman DA, Cochran B, Wu J, Habib AA. Cytoplasmic TRADD confers a worse prognosis in glioblastoma. Neoplasia (New York, N.Y.). 15: 888-97. PMID 23908590 DOI: 10.1593/Neo.13608 |
0.339 |
|
| 2013 |
Bey EA, Reinicke KE, Srougi MC, Varnes M, Anderson VE, Pink JJ, Li LS, Patel M, Cao L, Moore Z, Rommel A, Boatman M, Lewis C, Euhus DM, Bornmann WG, ... ... Boothman DA, et al. Catalase abrogates β-lapachone-induced PARP1 hyperactivation-directed programmed necrosis in NQO1-positive breast cancers Molecular Cancer Therapeutics. 12: 2110-2120. PMID 23883585 DOI: 10.1158/1535-7163.Mct-12-0962 |
0.775 |
|
| 2013 |
Wu K, Xie D, Zou Y, Zhang T, Pong RC, Xiao G, Fazli L, Gleave M, He D, Boothman DA, Hsieh JT. The mechanism of DAB2IP in chemoresistance of prostate cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4740-9. PMID 23838317 DOI: 10.1158/1078-0432.Ccr-13-0954 |
0.38 |
|
| 2013 |
Huang G, Chen H, Dong Y, Luo X, Yu H, Moore Z, Bey EA, Boothman DA, Gao J. Superparamagnetic iron oxide nanoparticles: amplifying ROS stress to improve anticancer drug efficacy. Theranostics. 3: 116-26. PMID 23423156 DOI: 10.7150/Thno.5411 |
0.394 |
|
| 2013 |
Lo KK, Bey EA, Patra B, Benson DD, Boothman DA, Silliman CC, Barnett CC. Hemoglobin-based oxygen carrier mitigates transfusion-mediated pancreas cancer progression. Annals of Surgical Oncology. 20: 2073-7. PMID 23328973 DOI: 10.1245/S10434-012-2842-0 |
0.335 |
|
| 2013 |
Klokov D, Leskov K, Araki S, Zou Y, Goetz EM, Luo X, Willson D, Boothman DA. Low dose IR-induced IGF-1-sCLU expression: a p53-repressed expression cascade that interferes with TGFβ1 signaling to confer a pro-survival bystander effect. Oncogene. 32: 479-90. PMID 22391565 DOI: 10.1038/Onc.2012.64 |
0.347 |
|
| 2013 |
Li LS, Reddy S, Gao J, Boothman DA, Sumer B, Yordy JS. Abstract 589: NQO1-dependent anticancer action with combination β-lapachone and ionizing radiation in the head and neck cancer. Cancer Research. 73: 589-589. DOI: 10.1158/1538-7445.Am2013-589 |
0.468 |
|
| 2013 |
Luo X, Patel M, Li L, Deberardinis R, Boothman DA. Abstract 4614: β-lapachone suppresses glucose metabolism in a NQO1-dependent, tumor-selective manner. Cancer Research. 73: 4614-4614. DOI: 10.1158/1538-7445.Am2013-4614 |
0.42 |
|
| 2013 |
Luo X, Li L, Huang X, Cao L, Moore Z, Deberardinis R, Brekken R, Gerson S, Liu L, Boothman DA. Abstract 3344: Inhibiting base excision repair synergistically enhances beta-lapachone-mediated ‘kiss of death’ for tumor-selective therapy of pancreatic cancer. Cancer Research. 73: 3344-3344. DOI: 10.1158/1538-7445.Am2013-3344 |
0.501 |
|
| 2013 |
Reddy S, Li L, Boothman DA, Sumer B, Yordy JS. NQO1-Mediated Synergistic Lethality in Combination With β-lapachone (β-lap) and Ionizing Radiation (IR) in Head-and-Neck Cancer (HNC) International Journal of Radiation Oncology Biology Physics. 87. DOI: 10.1016/J.Ijrobp.2013.06.357 |
0.334 |
|
| 2012 |
Huang X, Dong Y, Bey EA, Kilgore JA, Bair JS, Li LS, Patel M, Parkinson EI, Wang Y, Williams NS, Gao J, Hergenrother PJ, Boothman DA. An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis. Cancer Research. 72: 3038-47. PMID 22532167 DOI: 10.1158/0008-5472.Can-11-3135 |
0.459 |
|
| 2011 |
Leskov KS, Araki S, Lavik JP, Gomez JA, Gama V, Gonos ES, Trougakos IP, Matsuyama S, Boothman DA. CRM1 protein-mediated regulation of nuclear clusterin (nCLU), an ionizing radiation-stimulated, Bax-dependent pro-death factor. The Journal of Biological Chemistry. 286: 40083-90. PMID 21953454 DOI: 10.1074/Jbc.M111.252957 |
0.401 |
|
| 2011 |
Ding H, Yu H, Dong Y, Tian R, Huang G, Boothman DA, Sumer BD, Gao J. Photoactivation switch from type II to type I reactions by electron-rich micelles for improved photodynamic therapy of cancer cells under hypoxia. Journal of Controlled Release : Official Journal of the Controlled Release Society. 156: 276-80. PMID 21888934 DOI: 10.1016/J.Jconrel.2011.08.019 |
0.32 |
|
| 2011 |
Goetz EM, Shankar B, Zou Y, Morales JC, Luo X, Araki S, Bachoo R, Mayo LD, Boothman DA. ATM-dependent IGF-1 induction regulates secretory clusterin expression after DNA damage and in genetic instability. Oncogene. 30: 3745-54. PMID 21460853 DOI: 10.1038/Onc.2011.92 |
0.429 |
|
| 2011 |
Galindo CL, McIver LJ, Tae H, McCormick JF, Skinner MA, Hoeschele I, Lewis CM, Minna JD, Boothman DA, Garner HR. Sporadic breast cancer patients' germline DNA exhibit an AT-rich microsatellite signature. Genes, Chromosomes & Cancer. 50: 275-83. PMID 21319262 DOI: 10.1002/Gcc.20853 |
0.413 |
|
| 2011 |
Li LS, Bey EA, Dong Y, Meng J, Patra B, Yan J, Xie XJ, Brekken RA, Barnett CC, Bornmann WG, Gao J, Boothman DA. Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of β-lapachone for pancreatic cancer therapy Clinical Cancer Research. 17: 275-285. PMID 21224367 DOI: 10.1158/1078-0432.Ccr-10-1983 |
0.389 |
|
| 2011 |
Doi S, Zou Y, Togao O, Pastor JV, John GB, Wang L, Shiizaki K, Gotschall R, Schiavi S, Yorioka N, Takahashi M, Boothman DA, Kuro-o M. Klotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in mice. The Journal of Biological Chemistry. 286: 8655-65. PMID 21209102 DOI: 10.1074/Jbc.M110.174037 |
0.399 |
|
| 2011 |
Galindo CL, McCormick JF, Bubb VJ, Abid Alkadem DH, Li LS, McIver LJ, George AC, Boothman DA, Quinn JP, Skinner MA, Garner HR. A long AAAG repeat allele in the 5' UTR of the ERR-γ gene is correlated with breast cancer predisposition and drives promoter activity in MCF-7 breast cancer cells. Breast Cancer Research and Treatment. 130: 41-8. PMID 21153485 DOI: 10.1007/S10549-010-1237-9 |
0.341 |
|
| 2011 |
Dong Y, Bey EA, Li L, Boothman DA. Abstract 5369: Prostate cancer radiosensitization through PARP-1 hyperactivation Cancer Research. 71: 5369-5369. DOI: 10.1158/1538-7445.Am2011-5369 |
0.476 |
|
| 2010 |
Dong Y, Bey EA, Li LS, Kabbani W, Yan J, Xie XJ, Hsieh JT, Gao J, Boothman DA. Prostate cancer radiosensitization through poly(ADP-Ribose) polymerase-1 hyperactivation. Cancer Research. 70: 8088-96. PMID 20940411 DOI: 10.1158/0008-5472.Can-10-1418 |
0.407 |
|
| 2010 |
Camacho CV, Mukherjee B, McEllin B, Ding LH, Hu B, Habib AA, Xie XJ, Nirodi CS, Saha D, Story MD, Balajee AS, Bachoo RM, Boothman DA, Burma S. Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks. Carcinogenesis. 31: 1889-96. PMID 20663777 DOI: 10.1093/Carcin/Bgq153 |
0.379 |
|
| 2010 |
Blanco E, Bey EA, Khemtong C, Yang SG, Setti-Guthi J, Chen H, Kessinger CW, Carnevale KA, Bornmann WG, Boothman DA, Gao J. β-lapachone micellar nanotherapeutics for non-small cell lung cancer therapy Cancer Research. 70: 3896-3904. PMID 20460521 DOI: 10.1158/0008-5472.Can-09-3995 |
0.405 |
|
| 2010 |
Xie D, Gore C, Liu J, Pong RC, Mason R, Hao G, Long M, Kabbani W, Yu L, Zhang H, Chen H, Sun X, Boothman DA, Min W, Hsieh JT. Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis. Proceedings of the National Academy of Sciences of the United States of America. 107: 2485-90. PMID 20080667 DOI: 10.1073/Pnas.0908133107 |
0.312 |
|
| 2010 |
Araki S, Eitel JA, Batuello CN, Bijangi-Vishehsaraei K, Xie XJ, Danielpour D, Pollok KE, Boothman DA, Mayo LD. TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer. The Journal of Clinical Investigation. 120: 290-302. PMID 19955655 DOI: 10.1172/Jci39194 |
0.443 |
|
| 2010 |
Garner H, McCormick J, Li L, McIver L, Bubb V, George A, Boothman D, Quinn J, Galindo C. Abstract P2-06-03: A Polymorphic AAAG Repeat in the Estrogen Receptor-Related-Gamma Gene May Represent a Breast Cancer Predisposition Biomarker Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P2-06-03 |
0.362 |
|
| 2009 |
Konstantinidou G, Bey EA, Rabellino A, Schuster K, Maira MS, Gazdar AF, Amici A, Boothman DA, Scaglioni PP. Dual phosphoinositide 3-kinase/mammalian target of rapamycin blockade is an effective radiosensitizing strategy for the treatment of non-small cell lung cancer harboring K-RAS mutations. Cancer Research. 69: 7644-52. PMID 19789349 DOI: 10.1158/0008-5472.Can-09-0823 |
0.331 |
|
| 2009 |
Li LS, Morales JC, Veigl M, Sedwick D, Greer S, Meyers M, Wagner M, Fishel R, Boothman DA. DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets. British Journal of Pharmacology. 158: 679-92. PMID 19775280 DOI: 10.1111/J.1476-5381.2009.00423.X |
0.585 |
|
| 2009 |
Chauncey SS, Boothman DA, Habib AA. The receptor interacting protein 1 mediates a link between NFkappaB and PI3-kinase signaling. Cell Cycle (Georgetown, Tex.). 8: 2671-2. PMID 19690459 DOI: 10.4161/Cc.8.17.9337 |
0.352 |
|
| 2009 |
Markopoulou S, Kontargiris E, Batsi C, Tzavaras T, Trougakos I, Boothman DA, Gonos ES, Kolettas E. Vanadium-induced apoptosis of HaCaT cells is mediated by c-fos and involves nuclear accumulation of clusterin. The Febs Journal. 276: 3784-99. PMID 19531052 DOI: 10.1111/J.1742-4658.2009.07093.X |
0.404 |
|
| 2009 |
Mukherjee B, McEllin B, Camacho CV, Tomimatsu N, Sirasanagandala S, Nannepaga S, Hatanpaa KJ, Mickey B, Madden C, Maher E, Boothman DA, Furnari F, Cavenee WK, Bachoo RM, Burma S. EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma. Cancer Research. 69: 4252-9. PMID 19435898 DOI: 10.1158/0008-5472.Can-08-4853 |
0.416 |
|
| 2009 |
Park S, Zhao D, Hatanpaa KJ, Mickey BE, Saha D, Boothman DA, Story MD, Wong ET, Burma S, Georgescu MM, Rangnekar VM, Chauncey SS, Habib AA. RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN. Cancer Research. 69: 4107-11. PMID 19435890 DOI: 10.1158/0008-5472.Can-09-0474 |
0.313 |
|
| 2009 |
Park S, Hatanpaa KJ, Xie Y, Mickey BE, Madden CJ, Raisanen JM, Ramnarain DB, Xiao G, Saha D, Boothman DA, Zhao D, Bachoo RM, Pieper RO, Habib AA. The receptor interacting protein 1 inhibits p53 induction through NF-kappaB activation and confers a worse prognosis in glioblastoma. Cancer Research. 69: 2809-16. PMID 19339267 DOI: 10.1158/0008-5472.Can-08-4079 |
0.363 |
|
| 2009 |
Pucci S, Mazzarelli P, Paola M, Sesti F, Fabiola S, Boothman DA, David BA, Spagnoli LG, Luigi SG. Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progression. Cell Cycle (Georgetown, Tex.). 8: 473-81. PMID 19177010 DOI: 10.4161/Cc.8.3.7652 |
0.411 |
|
| 2009 |
Trougakos IP, Djeu JY, Gonos ES, Boothman DA. Advances and challenges in basic and translational research on clusterin. Cancer Research. 69: 403-6. PMID 19147550 DOI: 10.1158/0008-5472.Can-08-2912 |
0.311 |
|
| 2009 |
Dong Y, Chin SF, Blanco E, Bey EA, Kabbani W, Xie XJ, Bornmann WG, Boothman DA, Gao J. Intratumoral delivery of β-lapachone via polymer implants for prostate cancer therapy Clinical Cancer Research. 15: 131-139. PMID 19118040 DOI: 10.1158/1078-0432.Ccr-08-1691 |
0.385 |
|
| 2009 |
Trougakos IP, Lourda M, Antonelou MH, Kletsas D, Gorgoulis VG, Papassideri IS, Zou Y, Margaritis LH, Boothman DA, Gonos ES. Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 48-59. PMID 19118032 DOI: 10.1158/1078-0432.Ccr-08-1805 |
0.442 |
|
| 2009 |
Bey E, Kessinger C, Blanco E, Bachoo R, Williams N, Boothman D. Synergisitic inhibition of DNA repair by combining ß-lapachone with Nu7026 as a strategy for killing primary and metastatic breast cancers. Cancer Research. 69: 3078. DOI: 10.1158/0008-5472.Sabcs-3078 |
0.405 |
|
| 2008 |
Wagner MW, Long SL, Morales JC, Galindo CL, Garner HR, Bornmann WG, Boothman DA. Role of c-Abl kinase in DNA mismatch repair-dependent G2 cell cycle checkpoint arrest responses Journal of Biological Chemistry. 283: 21382-21393. PMID 18480061 DOI: 10.1074/Jbc.M709953200 |
0.383 |
|
| 2008 |
Li LS, Morales JC, Hwang A, Wagner MW, Boothman DA. DNA mismatch repair-dependent activation of c-Abl/p73alpha/GADD45alpha-mediated apoptosis. The Journal of Biological Chemistry. 283: 21394-403. PMID 18480060 DOI: 10.1074/Jbc.M709954200 |
0.406 |
|
| 2008 |
Suzuki M, Boothman DA. Stress-induced premature senescence (SIPS)--influence of SIPS on radiotherapy. Journal of Radiation Research. 49: 105-12. PMID 18219184 DOI: 10.1269/Jrr.07081 |
0.451 |
|
| 2007 |
Choi EK, Terai K, Ji IM, Kook YH, Park KH, Oh ET, Griffin RJ, Lim BU, Kim JS, Lee DS, Boothman DA, Loren M, Song CW, Park HJ. Upregulation of NAD(P)H:quinone oxidoreductase by radiation potentiates the effect of bioreductive beta-lapachone on cancer cells. Neoplasia (New York, N.Y.). 9: 634-42. PMID 17786182 DOI: 10.1593/Neo.07397 |
0.455 |
|
| 2007 |
Bentle MS, Reinicke KE, Dong Y, Bey EA, Boothman DA. Nonhomologous end joining is essential for cellular resistance to the novel antitumor agent, beta-lapachone. Cancer Research. 67: 6936-45. PMID 17638905 DOI: 10.1158/0008-5472.Can-07-0935 |
0.797 |
|
| 2007 |
Gomez JA, Gama V, Yoshida T, Sun W, Hayes P, Leskov K, Boothman D, Matsuyama S. Bax-inhibiting peptides derived from Ku70 and cell-penetrating pentapeptides. Biochemical Society Transactions. 35: 797-801. PMID 17635151 DOI: 10.1042/Bst0350797 |
0.381 |
|
| 2007 |
Bey EA, Bentle MS, Reinicke KE, Dong Y, Yang CR, Girard L, Minna JD, Bornmann WG, Gao J, Boothman DA. An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by β-lapachone Proceedings of the National Academy of Sciences of the United States of America. 104: 11832-11837. PMID 17609380 DOI: 10.1073/Pnas.0702176104 |
0.796 |
|
| 2007 |
Blanco E, Bey EA, Dong Y, Weinberg BD, Sutton DM, Boothman DA, Gao J. Beta-lapachone-containing PEG-PLA polymer micelles as novel nanotherapeutics against NQO1-overexpressing tumor cells. Journal of Controlled Release : Official Journal of the Controlled Release Society. 122: 365-74. PMID 17574288 DOI: 10.1016/J.Jconrel.2007.04.014 |
0.42 |
|
| 2007 |
Shannan B, Seifert M, Boothman DA, Tilgen W, Reichrath J. Clusterin over-expression modulates proapoptotic and antiproliferative effects of 1,25(OH)2D3 in prostate cancer cells in vitro The Journal of Steroid Biochemistry and Molecular Biology. 103: 721-725. PMID 17224269 DOI: 10.1016/J.Jsbmb.2006.12.068 |
0.346 |
|
| 2006 |
Sutton D, Kim S, Shuai X, Leskov K, Marques JT, Williams BR, Boothman DA, Gao J. Efficient suppression of secretory clusterin levels by polymer-siRNA nanocomplexes enhances ionizing radiation lethality in human MCF-7 breast cancer cells in vitro. International Journal of Nanomedicine. 1: 155-62. PMID 17722531 DOI: 10.2147/Nano.2006.1.2.155 |
0.385 |
|
| 2006 |
Nasongkla N, Bey E, Ren J, Ai H, Khemtong C, Guthi JS, Chin SF, Sherry AD, Boothman DA, Gao J. Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems. Nano Letters. 6: 2427-30. PMID 17090068 DOI: 10.1021/Nl061412U |
0.343 |
|
| 2006 |
Shannan B, Seifert M, Boothman DA, Tilgen W, Reichrath J. Clusterin and DNA repair: a new function in cancer for a key player in apoptosis and cell cycle control. Journal of Molecular Histology. 37: 183-188. PMID 17048076 DOI: 10.1007/S10735-006-9052-7 |
0.436 |
|
| 2006 |
Bey EA, Wuerzberger-Davis SM, Pink JJ, Yang CR, Araki S, Reinicke KE, Bentle MS, Dong Y, Cataldo E, Criswell TL, Wagner MW, Li L, Gao J, Boothman DA. Mornings with Art, lessons learned: feedback regulation, restriction threshold biology, and redundancy govern molecular stress responses. Journal of Cellular Physiology. 209: 604-10. PMID 17001694 DOI: 10.1002/Jcp.20783 |
0.779 |
|
| 2006 |
Bentle MS, Reinicke KE, Bey EA, Spitz DR, Boothman DA. Calcium-dependent modulation of poly(ADP-ribose) polymerase-1 alters cellular metabolism and DNA repair. The Journal of Biological Chemistry. 281: 33684-96. PMID 16920718 DOI: 10.1074/Jbc.M603678200 |
0.788 |
|
| 2006 |
Wang F, Blanco E, Ai H, Boothman DA, Gao J. Modulating beta-lapachone release from polymer millirods through cyclodextrin complexation. Journal of Pharmaceutical Sciences. 95: 2309-19. PMID 16883563 DOI: 10.1002/Jps.20721 |
0.304 |
|
| 2006 |
Bentle MS, Bey EA, Dong Y, Reinicke KE, Boothman DA. New tricks for old drugs: the anticarcinogenic potential of DNA repair inhibitors. Journal of Molecular Histology. 37: 203-18. PMID 16868862 DOI: 10.1007/S10735-006-9043-8 |
0.764 |
|
| 2006 |
Shannan B, Seifert M, Leskov K, Willis J, Boothman D, Tilgen W, Reichrath J. Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer. Cell Death and Differentiation. 13: 12-9. PMID 16179938 DOI: 10.1038/Sj.Cdd.4401779 |
0.41 |
|
| 2005 |
Park HJ, Choi EK, Choi J, Ahn KJ, Kim EJ, Ji IM, Kook YH, Ahn SD, Williams B, Griffin R, Boothman DA, Lee CK, Song CW. Heat-induced up-regulation of NAD(P)H:quinone oxidoreductase potentiates anticancer effects of beta-lapachone. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 8866-71. PMID 16361576 DOI: 10.1158/1078-0432.Ccr-05-0818 |
0.377 |
|
| 2005 |
Reinicke KE, Bey EA, Bentle MS, Pink JJ, Ingalls ST, Hoppel CL, Misico RI, Arzac GM, Burton G, Bornmann WG, Sutton D, Gao J, Boothman DA. Development of beta-lapachone prodrugs for therapy against human cancer cells with elevated NAD(P)H:quinone oxidoreductase 1 levels. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 3055-64. PMID 15837761 DOI: 10.1158/1078-0432.Ccr-04-2185 |
0.775 |
|
| 2005 |
Criswell T, Beman M, Araki S, Leskov K, Cataldo E, Mayo LD, Boothman DA. Delayed activation of insulin-like growth factor-1 receptor/Src/MAPK/Egr-1 signaling regulates clusterin expression, a pro-survival factor. The Journal of Biological Chemistry. 280: 14212-21. PMID 15689620 DOI: 10.1074/Jbc.M412569200 |
0.327 |
|
| 2005 |
Ough M, Lewis A, Bey EA, Gao J, Ritchie JM, Bornmann W, Boothman DA, Oberley LW, Cullen JJ. Efficacy of beta-lapachone in pancreatic cancer treatment: exploiting the novel, therapeutic target NQO1. Cancer Biology & Therapy. 4: 95-102. PMID 15662131 DOI: 10.4161/Cbt.4.1.1382 |
0.468 |
|
| 2005 |
Park HJ, Ahn KJ, Ahn SD, Choi E, Lee SW, Williams B, Kim EJ, Griffin R, Bey EA, Bornmann WG, Gao J, Boothman DA, Song CW. Susceptibility of cancer cells to β-lapachone is enhanced by ionizing radiation International Journal of Radiation Oncology Biology Physics. 61: 212-219. PMID 15629614 DOI: 10.1016/J.Ijrobp.2004.09.018 |
0.447 |
|
| 2005 |
Meyers M, Wagner MW, Mazurek A, Schmutte C, Fishel R, Boothman DA. DNA mismatch repair-dependent response to fluoropyrimidine-generated damage. The Journal of Biological Chemistry. 280: 5516-26. PMID 15611052 DOI: 10.1074/Jbc.M412105200 |
0.424 |
|
| 2005 |
Araki S, Israel S, Leskov KS, Criswell TL, Beman M, Klokov DY, Sampalth L, Reinicke KE, Cataldo E, Mayo LD, Boothman DA. Clusterin proteins: stress-inducible polypeptides with proposed functions in multiple organ dysfunction British Journal of Radiology. 106-113. DOI: 10.1259/Bjr/18105113 |
0.751 |
|
| 2004 |
Klokov D, Criswell T, Leskov KS, Araki S, Mayo L, Boothman DA. IR-inducible clusterin gene expression: a protein with potential roles in ionizing radiation-induced adaptive responses, genomic instability, and bystander effects. Mutation Research. 568: 97-110. PMID 15530543 DOI: 10.1016/J.Mrfmmm.2004.06.049 |
0.423 |
|
| 2004 |
Meyers M, Hwang A, Wagner MW, Boothman DA. Role of DNA mismatch repair in apoptotic responses to therapeutic agents. Environmental and Molecular Mutagenesis. 44: 249-64. PMID 15468331 DOI: 10.1002/Em.20056 |
0.486 |
|
| 2003 |
Nasongkla N, Wiedmann AF, Bruening A, Beman M, Ray D, Bornmann WG, Boothman DA, Gao J. Enhancement of Solubility and Bioavailability of β-Lapachone Using Cyclodextrin Inclusion Complexes Pharmaceutical Research. 20: 1626-1633. PMID 14620518 DOI: 10.1023/A:1026143519395 |
0.311 |
|
| 2003 |
Meyers M, Hwang A, Wagner MW, Bruening AJ, Veigl ML, Sedwick WD, Boothman DA. A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage. Oncogene. 22: 7376-88. PMID 14576845 DOI: 10.1038/Sj.Onc.1206941 |
0.403 |
|
| 2003 |
Criswell T, Klokov D, Beman M, Lavik JP, Boothman DA. Repression of IR-inducible clusterin expression by the p53 tumor suppressor protein. Cancer Biology & Therapy. 2: 372-80. PMID 14508108 DOI: 10.4161/Cbt.2.4.430 |
0.431 |
|
| 2003 |
Criswell T, Leskov K, Miyamoto S, Luo G, Boothman DA. Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation. Oncogene. 22: 5813-27. PMID 12947388 DOI: 10.1038/Sj.Onc.1206680 |
0.317 |
|
| 2003 |
Tagliarino C, Pink JJ, Reinicke KE, Simmers SM, Wuerzberger-Davis SM, Boothman DA. Mu-calpain activation in beta-lapachone-mediated apoptosis. Cancer Biology & Therapy. 2: 141-52. PMID 12750552 DOI: 10.4161/Cbt.2.2.237 |
0.783 |
|
| 2003 |
Sawada M, Sun W, Hayes P, Leskov K, Boothman DA, Matsuyama S. Ku70 suppresses the apoptotic translocation of Bax to mitochondria. Nature Cell Biology. 5: 320-9. PMID 12652308 DOI: 10.1038/Ncb950 |
0.389 |
|
| 2003 |
Leskov KS, Klokov DY, Li J, Kinsella TJ, Boothman DA. Synthesis and functional analyses of nuclear clusterin, a cell death protein. The Journal of Biological Chemistry. 278: 11590-600. PMID 12551933 DOI: 10.1074/Jbc.M209233200 |
0.336 |
|
| 2001 |
Leskov KS, Criswell T, Antonio S, Li J, Yang CR, Kinsella TJ, Boothman DA. When X-ray-inducible proteins meet DNA double strand break repair. Seminars in Radiation Oncology. 11: 352-72. PMID 11677660 DOI: 10.1053/Srao.2001.26912 |
0.428 |
|
| 2001 |
Planchon SM, Pink JJ, Tagliarino C, Bornmann WG, Varnes ME, Boothman DA. β-Lapachone-induced apoptosis in human prostate cancer cells: Involvement of NQO1/xip3 Experimental Cell Research. 267: 95-106. PMID 11412042 DOI: 10.1006/Excr.2001.5234 |
0.466 |
|
| 2001 |
Tagliarino C, Pink JJ, Dubyak GR, Nieminenll AL, Boothman DA. Calcium Is a Key Signaling Molecule in β-Lapachone-mediated Cell Death Journal of Biological Chemistry. 276: 19150-19159. PMID 11279125 DOI: 10.1074/Jbc.M100730200 |
0.4 |
|
| 2001 |
Tagliarino C, Pink JJ, Boothman DA. Calpains and apoptosis Animal Cells and Systems. 5: 267-274. DOI: 10.1080/12265071.2001.9647614 |
0.367 |
|
| 2000 |
Miyamoto S, Huang TT, Wuerzberger-Davis S, Bornmann WG, Pink JJ, Tagliarino C, Kinsella TJ, Boothman DA. Cellular and molecular responses to topoisomerase I poisons: Exploiting synergy for improved radiotherapy Annals of the New York Academy of Sciences. 922: 274-292. PMID 11193903 DOI: 10.1111/J.1749-6632.2000.Tb07045.X |
0.502 |
|
| 2000 |
Yang CR, Leskov K, Hosley-Eberlein K, Criswell T, Pink JJ, Kinsella TJ, Boothman DA. Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death. Proceedings of the National Academy of Sciences of the United States of America. 97: 5907-12. PMID 10823943 DOI: 10.1073/Pnas.97.11.5907 |
0.447 |
|
| 2000 |
Huang TT, Wuerzberger-Davis SM, Seufzer BJ, Shumway SD, Kurama T, Boothman DA, Miyamoto S. NF-kappaB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events. The Journal of Biological Chemistry. 275: 9501-9. PMID 10734098 DOI: 10.1074/Jbc.275.13.9501 |
0.358 |
|
| 2000 |
Pink JJ, Wuerzberger-Davis S, Tagliarino C, Planchon SM, Yang X, Froelich CJ, Boothman DA. Activation of a cysteine protease in MCF-7 and T47D breast cancer cells during beta-lapachone-mediated apoptosis. Experimental Cell Research. 255: 144-55. PMID 10694431 DOI: 10.1006/Excr.1999.4790 |
0.444 |
|
| 2000 |
Pink JJ, Planchon SM, Tagliarino C, Varnes ME, Siegel D, Boothman DA. NAD(P)H:Quinone Oxidoreductase Activity Is the Principal Determinant of β-Lapachone Cytotoxicity Journal of Biological Chemistry. 275: 5416-5424. PMID 10681517 DOI: 10.1074/Jbc.275.8.5416 |
0.406 |
|
| 2000 |
Yang CR, Wilson-Van Patten C, Planchon SM, Wuerzberger-Davis SM, Davis TW, Cuthill S, Miyamoto S, Boothman DA. Coordinate modulation of Sp1, NF-kappa B, and p53 in confluent human malignant melanoma cells after ionizing radiation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 379-90. PMID 10657994 DOI: 10.1096/Fasebj.14.2.379 |
0.4 |
|
| 1999 |
Separovic D, Pink JJ, Oleinick NA, Kester M, Boothman DA, McLoughlin M, Peña LA, Haimovitz-Friedman A. Niemann-Pick human lymphoblasts are resistant to phthalocyanine 4-photodynamic therapy-induced apoptosis. Biochemical and Biophysical Research Communications. 258: 506-512. PMID 10329416 DOI: 10.1006/Bbrc.1999.0670 |
0.365 |
|
| 1999 |
Yang CR, Yeh S, Leskov K, Odegaard E, Hsu HL, Chang C, Kinsella TJ, Chen DJ, Boothman DA. Isolation of Ku70-binding proteins (KUBs). Nucleic Acids Research. 27: 2165-74. PMID 10219089 DOI: 10.1093/Nar/27.10.2165 |
0.376 |
|
| 1999 |
Planchon SM, Wuerzberger-Davis SM, Pink JJ, Robertson KA, Bornmann WG, Boothman DA. Bcl-2 protects against beta-lapachone-mediated caspase 3 activation and apoptosis in human myeloid leukemia (HL-60) cells. Oncology Reports. 6: 485-492. PMID 10203579 DOI: 10.3892/Or.6.3.485 |
0.451 |
|
| 1999 |
Badie B, Goh CS, Klaver J, Herweijer H, Boothman DA. Combined radiation and p53 gene therapy of malignant glioma cells. Cancer Gene Therapy. 6: 155-62. PMID 10195882 DOI: 10.1038/Sj.Cgt.7700009 |
0.392 |
|
| 1998 |
Odegaard E, Yang CR, Boothman DA. DNA-dependent protein kinase does not play a role in adaptive survival responses to ionizing radiation. Environmental Health Perspectives. 106: 301-305. PMID 9539023 DOI: 10.1289/Ehp.98106S1301 |
0.332 |
|
| 1998 |
Badie B, Kramar MH, Lau R, Boothman DA, Economou JS, Black KL. Adenovirus-mediated p53 gene delivery potentiates the radiation-induced growth inhibition of experimental brain tumors. Journal of Neuro-Oncology. 37: 217-222. PMID 9524079 DOI: 10.1023/A:1005924925149 |
0.36 |
|
| 1998 |
Boothman DA, Odegaard E, Yang CR, Hosley K, Mendonca MS. Molecular analyses of adaptive survival responses (ASRs): role of ASRs in radiotherapy Human & Experimental Toxicology. 17: 448-453. DOI: 10.1191/096032798678909070 |
0.431 |
|
| 1997 |
Boothman DA, Burrows HL, Yang CR, Davis TW, Wuerzberger SM, Planchon SM, Odegaard E, Lewis JE, Pink J, Meyers M, Patten CW, Sharda N, Kinsella TJ. Damage-sensing mechanisms in human cells after ionizing radiation. Stem Cells (Dayton, Ohio). 15: 27-42. PMID 9368284 DOI: 10.1002/Stem.5530150707 |
0.431 |
|
| 1996 |
Boothman DA, Meyers M, Odegaard E, Wang M. Altered G1 checkpoint control determines adaptive survival responses to ionizing radiation Mutation Research. 358: 143-153. PMID 8946019 DOI: 10.1016/S0027-5107(96)00115-7 |
0.409 |
|
| 1996 |
Lamond JP, Wang M, Kinsella TJ, Boothman DA. Radiation lethality enhancement with 9-aminocamptothecin: comparison to other topoisomerase I inhibitors. International Journal of Radiation Oncology, Biology, Physics. 36: 369-76. PMID 8892462 DOI: 10.1016/S0360-3016(96)00326-4 |
0.321 |
|
| 1996 |
Lamond JP, Wang M, Kinsella TJ, Boothman DA. Concentration and timing dependence of lethality enhancement between topotecan, a topoisomerase I inhibitor, and ionizing radiation. International Journal of Radiation Oncology, Biology, Physics. 36: 361-8. PMID 8892461 DOI: 10.1016/S0360-3016(96)00328-8 |
0.366 |
|
| 1996 |
Lamond JP, Mehta MP, Boothman DA. The potential of topoisomerase I inhibitors in the treatment of CNS malignancies: Report of a synergistic effect between topotecan and radiation Journal of Neuro-Oncology. 30: 1-6. PMID 8864997 DOI: 10.1007/Bf00177437 |
0.321 |
|
| 1996 |
Sharda NN, Yang C, Odegaard E, Cuthill S, Davis TA, Reznikoff K, Kinsella TJ, Boothman DA. 2221 pRb alterations abrogate cell cycle control and increase apoptosis and radiosensitivity International Journal of Radiation Oncology*Biology*Physics. 36: 385. DOI: 10.1016/S0360-3016(97)85794-X |
0.39 |
|
| 1994 |
Boothman DA, Davis TW, Sahijdak WM. Enhanced Expression Of Thymidine Kinase In Human Cells Following Ionizing Radiation International Journal of Radiation Oncology Biology Physics. 30: 391-398. PMID 7928466 DOI: 10.1016/0360-3016(94)90019-1 |
0.332 |
|
| 1994 |
Boothman DA. Enhanced Malignant Transformation Is Accompanied by Increased Survival Recovery after Ionizing Radiation in Chinese Hamster Embryo Fibroblasts Radiation Research. 138. DOI: 10.2307/3578778 |
0.413 |
|
| 1994 |
Boothman DA, Lee IW, Sahijdak WM. Isolation of an X-ray-responsive element in the promoter region of tissue-type plasminogen activator: potential uses of X-ray-responsive elements for gene therapy. Radiation Research. 138. DOI: 10.2307/3578765 |
0.32 |
|
| 1994 |
Sahijdak WM, Yang C, Zuckerman JS, Meyers M, Boothman DA. Alterations in transcription factor binding in radioresistant human melanoma cells after ionizing radiation. Radiation Research. 138. DOI: 10.2307/3578760 |
0.31 |
|
| 1994 |
Boothman DA, Majmudar G, Johnson T. Immediate X-ray-inducible responses from mammalian cells Radiation Research. 138. DOI: 10.2307/3578759 |
0.343 |
|
| 1993 |
Boothman DA, Meyers M, Fukunaga N, Lee SW. Isolation of x-ray-inducible transcripts from radioresistant human melanoma cells Proceedings of the National Academy of Sciences of the United States of America. 90: 7200-7204. PMID 8346236 DOI: 10.1073/Pnas.90.15.7200 |
0.348 |
|
| 1992 |
Fukunaga N, Burrows HL, Meyers M, Schea RA, Boothman DA. Enhanced induction of tissue-type plasminogen activator in normal human cells compared to cancer-prone cells following ionizing radiation. International Journal of Radiation Oncology, Biology, Physics. 24: 949-57. PMID 1447036 DOI: 10.1016/0360-3016(92)90479-2 |
0.388 |
|
| 1992 |
Boothman DA, Wang M, Schea RA, Burrows HL, Strickfaden S, Owens JK. Posttreatment exposure to camptothecin enhances the lethal effects of x-rays on radioresistant human malignant melanoma cells. International Journal of Radiation Oncology, Biology, Physics. 24: 939-48. PMID 1332930 DOI: 10.1016/0360-3016(92)90478-Z |
0.406 |
|
| 1991 |
Hughes EN, Boothman DA. Effect of caffeine on the expression of a major X-ray induced protein in human tumor cells. Radiation Research. 125: 313-317. DOI: 10.2307/3578116 |
0.347 |
|
| 1991 |
Boothman DA, Wang M, Lee SW. Induction of Tissue-type Plasminogen Activator by Ionizing Radiation in Human Malignant Melanoma Cells Cancer Research. 51: 5587-5595. DOI: 10.1016/B978-0-12-168561-4.50788-5 |
0.309 |
|
| 1991 |
Fukunaga N, Boothman D. Induction of tissue-type plasminogen activator by ionizing radiation in normal and cancer-prone human cells International Journal of Radiation Oncology Biology Physics. 21: 147. DOI: 10.1016/0360-3016(91)90492-M |
0.365 |
|
| 1990 |
Santos O, Perez LM, Briggle TV, Boothman DA, Greer SB. Radiation, pool size and incorporation studies in mice with 5-chloro-2′-deoxycytidine International Journal of Radiation Oncology, Biology, Physics. 19: 357-365. PMID 2394614 DOI: 10.1016/0360-3016(90)90544-T |
0.571 |
|
| 1990 |
Hughes EN, Boothman D. DNA damage inducible responses in human cells International Journal of Radiation Oncology Biology Physics. 19: 194. DOI: 10.1016/0360-3016(90)90785-I |
0.393 |
|
| 1989 |
Boothman DA, Pardee AB. Inhibition of radiation-induced neoplastic transformation by β-lapachone Proceedings of the National Academy of Sciences of the United States of America. 86: 4963-4967. PMID 2740334 DOI: 10.1073/Pnas.86.13.4963 |
0.591 |
|
| 1989 |
Boothman DA, Briggle TV, Greer S. Exploitation of elevated pyrimidine deaminating enzymes for selective chemotherapy Pharmacology & Therapeutics. 42: 65-88. PMID 2657808 DOI: 10.1016/0163-7258(89)90022-3 |
0.465 |
|
| 1989 |
Boothman DA, Geller AI, Pardee AB. Expression of the E. coli Lac Z gene from a defective HSV-1 vector in various human normal, cancer-prone and tumor cells Febs Letters. 258: 159-162. PMID 2556295 DOI: 10.1016/0014-5793(89)81640-0 |
0.545 |
|
| 1988 |
Boothman DA, Schlegel R, Pardee AB. Anticarcinogenic potential of DNA-repair modulators Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 202: 393-411. PMID 2973563 DOI: 10.1016/0027-5107(88)90201-1 |
0.588 |
|
| 1986 |
Briggle TV, Boothman DA, Pfaffenberger CD, Greer S. Analysis of 5-fluoro-2′-deoxycytidine and 5-trifluoromethyl-2′-deoxycytidine and their related antimetabolites by high-performance liquid chromatography Journal of Chromatography B: Biomedical Sciences and Applications. 381: 343-355. PMID 2944908 DOI: 10.1016/S0378-4347(00)83600-2 |
0.49 |
|
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