Mohamed Trebak - Publications

Affiliations: 
Center for Cardiovascular Science Albany Medical College of Union University 
Area:
Molecular Biology, Oncology, General Biophysics

141 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Trebak M, Machaca K, Hogan PG. The Reappraisal of the Reappraisal-CRAC Channels Are Activated by L-Type Ca Channel Blockers, Reply to Bird et al. Function (Oxford, England). 5: zqae007. PMID 38486979 DOI: 10.1093/function/zqae007  0.356
2024 Lee L, Yoast R, Emrich S, Trebak M, Kirk V, Sneyd J. Emergence of broad cytosolic Ca oscillations in the absence of CRAC channels: A model for CRAC-mediated negative feedback on PLC and Ca oscillations through PKC. Journal of Theoretical Biology. 581: 111740. PMID 38253220 DOI: 10.1016/j.jtbi.2024.111740  0.485
2023 Pathak T, Benson JC, Johnson MT, Xin P, Abdelnaby AE, Walter V, Koltun WA, Yochum GS, Hempel N, Trebak M. Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway. Biorxiv : the Preprint Server For Biology. PMID 37873177 DOI: 10.1101/2023.10.02.560521  0.432
2023 Benson JC, Romito O, Abdelnaby AE, Xin P, Pathak T, Weir SE, Kirk V, Castaneda F, Yoast RE, Emrich SM, Tang PW, Yule DI, Hempel N, Potier-Cartereau M, Sneyd J, ... Trebak M, et al. A multiple-oscillator mechanism underlies antigen-induced Ca oscillations in Jurkat T-cells. The Journal of Biological Chemistry. 105310. PMID 37778728 DOI: 10.1016/j.jbc.2023.105310  0.513
2023 Benson JC, Trebak M. Too much of a good thing: The case of SOCE in cellular apoptosis. Cell Calcium. 111: 102716. PMID 36931194 DOI: 10.1016/j.ceca.2023.102716  0.481
2023 Emrich SM, Yoast RE, Zhang X, Fike AJ, Wang YH, Bricker KN, Tao AY, Xin P, Walter V, Johnson MT, Pathak T, Straub AC, Feske S, Rahman ZSM, Trebak M. Orai3 and Orai1 mediate CRAC channel function and metabolic reprogramming in B cells. Elife. 12. PMID 36803766 DOI: 10.7554/eLife.84708  0.418
2022 Emrich SM, Yoast RE, Fike AJ, Bricker KN, Xin P, Zhang X, Rahman ZSM, Trebak M. The mitochondrial sodium/calcium exchanger NCLX (Slc8b1) in B lymphocytes. Cell Calcium. 108: 102667. PMID 36308855 DOI: 10.1016/j.ceca.2022.102667  0.351
2022 Johnson MT, Benson JC, Pathak T, Xin P, McKernan AS, Emrich SM, Yoast RE, Walter V, Straub AC, Trebak M. The airway smooth muscle sodium/calcium exchanger NCLX is critical for airway remodeling and hyperresponsiveness in asthma. The Journal of Biological Chemistry. 102259. PMID 35841929 DOI: 10.1016/j.jbc.2022.102259  0.454
2022 Krishnan V, Ali S, Gonzales AL, Thakore P, Griffin CS, Yamasaki E, Alvarado MG, Johnson MT, Trebak M, Earley S. STIM1-dependent peripheral coupling governs the contractility of vascular smooth muscle cells. Elife. 11. PMID 35147077 DOI: 10.7554/eLife.70278  0.525
2022 Ahmad M, Ong HL, Saadi H, Son GY, Shokatian Z, Terry LE, Trebak M, Yule DI, Ambudkar I. Functional communication between IPR and STIM2 at subthreshold stimuli is a critical checkpoint for initiation of SOCE. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35022238 DOI: 10.1073/pnas.2114928118  0.343
2022 Johnson MT, Xin P, Benson JC, Pathak T, Walter V, Emrich SM, Yoast RE, Zhang X, Cao G, Panettieri RA, Trebak M. STIM1 is a core trigger of airway smooth muscle remodeling and hyperresponsiveness in asthma. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 34949717 DOI: 10.1073/pnas.2114557118  0.335
2021 Emrich SM, Yoast RE, Trebak M. Physiological Functions of CRAC Channels. Annual Review of Physiology. PMID 34637326 DOI: 10.1146/annurev-physiol-052521-013426  0.528
2021 Yoast RE, Emrich SM, Zhang X, Xin P, Arige V, Pathak T, Benson JC, Johnson MT, Abdelnaby AE, Lakomski N, Hempel N, Han JM, Dupont G, Yule DI, Sneyd J, ... Trebak M, et al. The Mitochondrial Ca Uniporter is a Central Regulator of Interorganellar Ca Transfer and NFAT Activation. The Journal of Biological Chemistry. 101174. PMID 34499925 DOI: 10.1016/j.jbc.2021.101174  0.472
2021 Arige V, Emrich SM, Yoast RE, Trebak M, Yule DI. A protocol for detecting elemental calcium signals (Ca puffs) in mammalian cells using total internal reflection fluorescence microscopy. Star Protocols. 2: 100618. PMID 34195673 DOI: 10.1016/j.xpro.2021.100618  0.301
2021 Baraniak JH, Zhou Y, Nwokonko RM, Jennette MR, Kazzaz SA, Stenson JM, Whitsell AL, Wang Y, Trebak M, Gill DL. Orai channel C-terminal peptides are key modulators of STIM-Orai coupling and calcium signal generation. Cell Reports. 35: 109322. PMID 34192542 DOI: 10.1016/j.celrep.2021.109322  0.433
2021 Gammons J, Trebak M, Mancarella S. Cardiac-Specific Deletion of Orai3 Leads to Severe Dilated Cardiomyopathy and Heart Failure in Mice. Journal of the American Heart Association. 10: e019486. PMID 33849280 DOI: 10.1161/JAHA.120.019486  0.328
2021 Emrich SM, Yoast RE, Xin P, Arige V, Wagner LE, Hempel N, Gill DL, Sneyd J, Yule DI, Trebak M. Omnitemporal choreographies of all five STIM/Orai and IPRs underlie the complexity of mammalian Ca signaling. Cell Reports. 34: 108760. PMID 33657364 DOI: 10.1016/j.celrep.2021.108760  0.477
2020 Yoast RE, Emrich SM, Trebak M. The anatomy of CRAC channel(s). Current Opinion in Physiology. 17: 89-95. PMID 32999945  0.52
2020 Pathak T, Trebak M. NCLX pumps up the heat. Cell Calcium. 92: 102280. PMID 32919102 DOI: 10.1016/J.Ceca.2020.102280  0.4
2020 Pathak T, Gueguinou M, Walter V, Delierneux C, Johnson MT, Zhang X, Xin P, Yoast RE, Emrich SM, Yochum GR, Sekler I, Koltun WA, Gill DL, Hempel N, Trebak M. Dichotomous role of the human mitochondrial Na/Ca/Li exchanger NCLX in colorectal cancer growth and metastasis. Elife. 9. PMID 32914752 DOI: 10.7554/Elife.59686  0.399
2020 Zhang X, Xin P, Yoast RE, Emrich SM, Johnson MT, Pathak T, Benson JC, Azimi I, Gill DL, Monteith GR, Trebak M. Distinct pharmacological profiles of ORAI1, ORAI2, and ORAI3 channels. Cell Calcium. 91: 102281. PMID 32896813 DOI: 10.1016/J.Ceca.2020.102281  0.539
2020 Johnson MT, Gudlur A, Zhang X, Xin P, Emrich SM, Yoast RE, Courjaret R, Nwokonko RM, Li W, Hempel N, Machaca K, Gill DL, Hogan PG, Trebak M. L-type Ca channel blockers promote vascular remodeling through activation of STIM proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 32641503 DOI: 10.1073/Pnas.2007598117  0.612
2020 Yoast RE, Emrich SM, Zhang X, Xin P, Johnson MT, Fike AJ, Walter V, Hempel N, Yule DI, Sneyd J, Gill DL, Trebak M. The native ORAI channel trio underlies the diversity of Ca signaling events. Nature Communications. 11: 2444. PMID 32415068 DOI: 10.1038/S41467-020-16232-6  0.615
2020 Azimi I, Stevenson RJ, Zhang X, Meizoso-Huesca A, Xin P, Johnson M, Flanagan JU, Chalmers SB, Yoast RE, Kapure JS, Ross BP, Vetter I, Ashton MR, Launikonis BS, Denny WA, ... Trebak M, et al. A new selective pharmacological enhancer of the Orai1 Ca channel reveals roles for Orai1 in smooth and skeletal muscle functions. Acs Pharmacology & Translational Science. 3: 135-147. PMID 32190822 DOI: 10.1021/acsptsci.9b00081  0.547
2020 Delierneux C, Kouba S, Shanmughapriya S, Potier-Cartereau M, Trebak M, Hempel N. Mitochondrial Calcium Regulation of Redox Signaling in Cancer. Cells. 9. PMID 32059571 DOI: 10.3390/Cells9020432  0.496
2020 Yoast RE, Emrich SM, Trebak M. The anatomy of native CRAC channel(s) Current Opinion in Physiology. 17: 89-95. DOI: 10.1016/J.Cophys.2020.07.012  0.597
2020 Krishnan V, Ali S, Thakore P, Johnson M, Yamasaki E, Trebak M, Earley S. STIM1 Maintains Stable Peripheral Coupling in Fully Differentiated Contractile Vascular Smooth Muscle Cells Independently of Ca2+ Store Depletion Biophysical Journal. 118: 329a. DOI: 10.1016/J.Bpj.2019.11.1842  0.535
2019 Kouba S, Braire J, Félix R, Chantôme A, Jaffrès PA, Lebreton J, Dubreuil D, Pipelier M, Zhang X, Trebak M, Vandier C, Mathé-Allainmat M, Potier-Cartereau M. Lipidic synthetic alkaloids as SK3 channel modulators. Synthesis and biological evaluation of 2-substituted tetrahydropyridine derivatives with potential anti-metastatic activity. European Journal of Medicinal Chemistry. 111854. PMID 31753515 DOI: 10.1016/J.Ejmech.2019.111854  0.514
2019 Gautier M, Trebak M, Fleig A, Vandier C, Ouadid-Ahidouch H. Ca channels in cancer. Cell Calcium. 84: 102083. PMID 31606459 DOI: 10.1016/J.Ceca.2019.102083  0.518
2019 Gautier M, Trebak M, Fleig A, Vandier C, Ouadid-Ahidouch H. Ca homeostasis and cancer. Cell Calcium. 84: 102084. PMID 31593838 DOI: 10.1016/J.Ceca.2019.102084  0.45
2019 Diwakar BT, Yoast R, Nettleford S, Qian F, Lee TJ, Berry S, Huffnagle I, Rossi RM, Trebak M, Paulson RF, Prabhu KS. Crth2 receptor signaling down-regulates lipopolysaccharide-induced NF-κB activation in murine macrophages changes in intracellular calcium. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802608R. PMID 31518163 DOI: 10.1096/Fj.201802608R  0.443
2019 Zhou Y, Nwokonko RM, Baraniak JH, Trebak M, Lee KPK, Gill DL. The remote allosteric control of Orai channel gating. Plos Biology. 17: e3000413. PMID 31469825 DOI: 10.1371/Journal.Pbio.3000413  0.548
2019 Zhang X, Pathak T, Yoast R, Emrich S, Xin P, Nwokonko RM, Johnson M, Wu S, Delierneux C, Gueguinou M, Hempel N, Putney JW, Gill DL, Trebak M. A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction. Nature Communications. 10: 1971. PMID 31036819 DOI: 10.1038/S41467-019-09593-0  0.576
2019 Xu M, Almasi S, Yang Y, Yan C, Sterea AM, Rizvi Syeda AK, Shen B, Richard Derek C, Huang P, Gujar S, Wang J, Zong WX, Trebak M, El Hiani Y, Dong XP. The lysosomal TRPML1 channel regulates triple negative breast cancer development by promoting mTORC1 and purinergic signaling pathways. Cell Calcium. 79: 80-88. PMID 30889511 DOI: 10.1016/J.Ceca.2019.02.010  0.346
2019 Emrich SM, Yoast RE, Xin P, Zhang X, Pathak T, Nwokonko R, Gueguinou M, Subedi KP, Zhou Y, Ambudkar IS, Hempel N, Machaca K, Gill DL, Trebak M. Crosstalk between N-terminal and C-terminal domains in stromal interaction molecule 2 (STIM2) determines enhanced STIM2 sensitivity. The Journal of Biological Chemistry. PMID 30824535 DOI: 10.1074/Jbc.Ra118.006801  0.562
2019 Johnson M, Trebak M. ORAI channels in cellular remodeling of cardiorespiratory disease. Cell Calcium. 79: 1-10. PMID 30772685 DOI: 10.1016/J.Ceca.2019.01.005  0.493
2019 Trebak M, Kinet JP. Calcium signalling in T cells. Nature Reviews. Immunology. PMID 30622345 DOI: 10.1038/S41577-018-0110-7  0.544
2018 Zhang X, Spinelli AM, Zhang W, Trebak M. Study of the Endogenous CRAC Channel Using shRNA-Mediated Gene Silencing. Methods in Molecular Biology (Clifton, N.J.). 1843: 137-145. PMID 30203284 DOI: 10.1007/978-1-4939-8704-7_12  0.591
2018 Liu Z, Wei Y, Zhang L, Yee PP, Johnson M, Zhang X, Gulley M, Atkinson JM, Trebak M, Wang HG, Li W. Induction of store-operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZ. Oncogene. PMID 30082911 DOI: 10.1038/S41388-018-0425-7  0.526
2018 Pathak T, Trebak M. Mitochondrial Ca signaling. Pharmacology & Therapeutics. PMID 30036491 DOI: 10.1016/J.Pharmthera.2018.07.001  0.463
2018 Johnson M, Trebak M. Slow Traffic Makes for Bad Circulation: The Case of β1 Subunit of BK Channels in Hypertension. Hypertension (Dallas, Tex. : 1979). PMID 30012872 DOI: 10.1161/Hypertensionaha.118.11237  0.325
2018 Cai X, Nwokonko RM, Loktionova NA, Abdulqadir R, Baraniak JH, Wang Y, Trebak M, Zhou Y, Gill DL. Pore properties of Orai1 calcium channel dimers and their activation by the STIM1 ER calcium sensor. The Journal of Biological Chemistry. PMID 29954946 DOI: 10.1074/Jbc.Ra118.003424  0.487
2018 Pierro C, Zhang X, Kankeu C, Trebak M, Bootman MD, Roderick HL. Oncogenic KRAS suppresses store-operated Ca entry and I through ERK pathway-dependent remodelling of STIM expression in colorectal cancer cell lines. Cell Calcium. 72: 70-80. PMID 29748135 DOI: 10.1016/J.Ceca.2018.03.002  0.545
2018 Zhou Y, Nwokonko RM, Cai X, Loktionova NA, Abdulqadir R, Xin P, Niemeyer BA, Wang Y, Trebak M, Gill DL. Cross-linking of Orai1 channels by STIM proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581306 DOI: 10.1073/Pnas.1720810115  0.468
2018 Nwokonko RM, Zhou Y, Cai X, Loktionova N, Trebak M, Gill DL. STIM Proteins Cluster Orai1 Channels and Modulate Receptor-Mediated Calcium Signals Biophysical Journal. 114: 285a. DOI: 10.1016/J.Bpj.2017.11.1637  0.398
2017 Verkhratsky A, Trebak M, Perocchi F, Khananishvili D, Sekler I. Crosslink of calcium and sodium signalling in health and disease. Experimental Physiology. PMID 29210126 DOI: 10.1113/Ep086534  0.544
2017 Tanwar J, Trebak M, Motiani RK. Cardiovascular and Hemostatic Disorders: Role of STIM and Orai Proteins in Vascular Disorders. Advances in Experimental Medicine and Biology. 993: 425-452. PMID 28900927 DOI: 10.1007/978-3-319-57732-6_22  0.808
2017 Trebak M, Putney JW. ORAI Calcium Channels. Physiology (Bethesda, Md.). 32: 332-342. PMID 28615316 DOI: 10.1152/Physiol.00011.2017  0.417
2017 Ben-Kasus Nissim T, Zhang X, Elazar A, Roy S, Stolwijk JA, Zhou Y, Motiani RK, Gueguinou M, Hempel N, Hershfinkel M, Gill DL, Trebak M, Sekler I. Mitochondria control store-operated Ca(2+) entry through Na(+) and redox signals. The Embo Journal. PMID 28219928 DOI: 10.15252/Embj.201592481  0.781
2017 Hempel N, Trebak M. Crosstalk between calcium and reactive oxygen species signaling in cancer. Cell Calcium. PMID 28143649 DOI: 10.1016/J.Ceca.2017.01.007  0.55
2017 Chandrasekaran A, Zhang X, Lee MY, Shapiro R, Trebak M, Melendez JA. H 2 O 2 and mTOR control the senescence-associated secretory phenotype by coordinating Ca 2+ transients through TRPC6 expression and activation Free Radical Biology and Medicine. 112: 55-56. DOI: 10.1016/J.Freeradbiomed.2017.10.075  0.595
2016 Zhou Y, Cai X, Loktionova NA, Wang X, Nwokonko RM, Wang X, Wang Y, Rothberg BS, Trebak M, Gill DL. The STIM1-binding site nexus remotely controls Orai1 channel gating. Nature Communications. 7: 13725. PMID 27929067 DOI: 10.1038/Ncomms13725  0.479
2016 Cai X, Zhou Y, Nwokonko RM, Loktionova NA, Wang X, Xin P, Trebak M, Wang Y, Gill DL. The Orai1 Store-operated Calcium Channel Functions as a Hexamer. The Journal of Biological Chemistry. PMID 27780862 DOI: 10.1074/Jbc.M116.758813  0.543
2016 Stolwijk JA, Zhang X, Gueguinou M, Zhang W, Matrougui K, Renken C, Trebak M. Calcium Signaling is Dispensable for Receptor-Regulation of Endothelial Barrier Function. The Journal of Biological Chemistry. PMID 27624938 DOI: 10.1074/Jbc.M116.756114  0.564
2016 Zhang X, Spinelli AM, Masiello T, Trebak M. Transient Receptor Potential Canonical 7 (TRPC7), a Calcium (Ca(2+)) Permeable Non-selective Cation Channel. Advances in Experimental Medicine and Biology. 898: 251-64. PMID 27161232 DOI: 10.1007/978-3-319-26974-0_11  0.536
2016 Wang H, Zhang X, Xue L, Xing J, Jouvin MH, Putney JW, Anderson MP, Trebak M, Kinet JP. Low-Voltage-Activated CaV3.1 Calcium Channels Shape T Helper Cell Cytokine Profiles. Immunity. PMID 27037192 DOI: 10.1016/J.Immuni.2016.01.015  0.403
2016 Spinelli AM, Trebak M. Orai channel-mediated Ca2+ signals in vascular and airway smooth muscle. American Journal of Physiology. Cell Physiology. 310: C402-13. PMID 26718630 DOI: 10.1152/Ajpcell.00355.2015  0.609
2016 Chandrasekaran A, Zhang X, Trebak M, Andres Melendez J. Redox-Dependent Calcium-Mediated Signaling Networks That Control the Senescence-Associated Secretory Phenotype Free Radical Biology and Medicine. 100: S81. DOI: 10.1016/J.Freeradbiomed.2016.10.202  0.562
2016 Zhou Y, Cai X, wang x, Loktionova NA, Wang X, Nwokonko RM, Trebak M, Gill DL. A C-Terminal Switch Gates the Orai1 Channel Biophysical Journal. 110: 359a-360a. DOI: 10.1016/J.Bpj.2015.11.1939  0.385
2016 Cai X, Zhou Y, Wang X, Loktionova N, Nwokonko R, Trebak M, Gill D. Orai1 Concatemers Reveal a Hexameric Orai1 Channel Assembly Biophysical Journal. 110: 264a-265a. DOI: 10.1016/J.Bpj.2015.11.1444  0.482
2015 Shakerley NL, Chandrasekaran A, Trebak M, Miller BA, Melendez JA. Francisella tularensis catalase restricts immune function by impairing TRPM2 channel activity. The Journal of Biological Chemistry. PMID 26679996 DOI: 10.1074/Jbc.M115.706879  0.5
2015 Desai PN, Zhang X, Wu S, Janoshazi A, Bolimuntha S, Putney JW, Trebak M. Multiple types of calcium channels arising from alternative translation initiation of the Orai1 message. Science Signaling. 8: ra74. PMID 26221052 DOI: 10.1126/Scisignal.Aaa8323  0.59
2015 Spinelli AM, Liu Y, Sun LY, González-Cobos JC, Backs J, Trebak M, Singer HA. Smooth muscle CaMKIIδ promotes allergen-induced airway hyperresponsiveness and inflammation. Pflugers Archiv : European Journal of Physiology. PMID 26089028 DOI: 10.1007/S00424-015-1713-5  0.799
2015 Hooper R, Zhang X, Webster M, Go C, Kedra J, Marchbank K, Gill DL, Weeraratna AT, Trebak M, Soboloff J. Novel PKC-mediated Control of Orai1 function in Invasive Melanoma. Molecular and Cellular Biology. PMID 26055321 DOI: 10.1128/Mcb.01500-14  0.392
2015 Kassan M, Ait-Aissa K, Ali M, Trebak M, Matrougui K. Augmented EGF receptor tyrosine kinase activity impairs vascular function by NADPH oxidase-dependent mechanism in type 2 diabetic mouse. Biochimica Et Biophysica Acta. 1853: 2404-10. PMID 26036345 DOI: 10.1016/J.Bbamcr.2015.05.032  0.346
2015 Vashisht A, Trebak M, Motiani RK. STIM and Orai proteins as novel targets for cancer therapy. A Review in the Theme: Cell and Molecular Processes in Cancer Metastasis. American Journal of Physiology. Cell Physiology. 309: C457-69. PMID 26017146 DOI: 10.1152/Ajpcell.00064.2015  0.748
2015 Zhou Y, Trebak M, Gill DL. Calcium signals tune the fidelity of transcriptional responses. Molecular Cell. 58: 197-9. PMID 25884365 DOI: 10.1016/J.Molcel.2015.04.003  0.434
2015 Zhang W, Zhang X, González-Cobos JC, Stolwijk JA, Matrougui K, Trebak M. Leukotriene-C4 synthase, a critical enzyme in the activation of store-independent Orai1/Orai3 channels, is required for neointimal hyperplasia. The Journal of Biological Chemistry. 290: 5015-27. PMID 25540197 DOI: 10.1074/Jbc.M114.625822  0.828
2015 Stolwijk JA, Matrougui K, Renken CW, Trebak M. Impedance analysis of GPCR-mediated changes in endothelial barrier function: overview and fundamental considerations for stable and reproducible measurements. PflüGers Archiv : European Journal of Physiology. 467: 2193-218. PMID 25537398 DOI: 10.1007/S00424-014-1674-0  0.324
2015 Saliba Y, Keck M, Marchand A, Atassi F, Ouillé A, Cazorla O, Trebak M, Pavoine C, Lacampagne A, Hulot JS, Farès N, Fauconnier J, Lompré AM. Emergence of Orai3 activity during cardiac hypertrophy. Cardiovascular Research. 105: 248-59. PMID 25213556 DOI: 10.1093/Cvr/Cvu207  0.516
2015 Kassan M, Zhang W, Aissa KA, Stolwijk J, Trebak M, Matrougui K. Differential role for stromal interacting molecule 1 in the regulation of vascular function. PflüGers Archiv : European Journal of Physiology. 467: 1195-202. PMID 24965067 DOI: 10.1007/S00424-014-1556-5  0.488
2014 Zhang W, Trebak M. Vascular balloon injury and intraluminal administration in rat carotid artery. Journal of Visualized Experiments : Jove. PMID 25548998 DOI: 10.3791/52045  0.339
2014 Zhang X, Trebak M. Transient receptor potential canonical 7: a diacylglycerol-activated non-selective cation channel. Handbook of Experimental Pharmacology. 222: 189-204. PMID 24756707 DOI: 10.1007/978-3-642-54215-2_8  0.518
2014 Galán M, Kassan M, Kadowitz PJ, Trebak M, Belmadani S, Matrougui K. Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction. Biochimica Et Biophysica Acta. 1843: 1063-75. PMID 24576409 DOI: 10.1016/J.Bbamcr.2014.02.009  0.332
2014 Zhang X, Zhang W, González-Cobos JC, Jardin I, Romanin C, Matrougui K, Trebak M. Complex role of STIM1 in the activation of store-independent Orai1/3 channels. The Journal of General Physiology. 143: 345-59. PMID 24567509 DOI: 10.1083/Jcb.2045Oia34  0.849
2014 Zhang X, Zhang W, González-Cobos JC, Jardin I, Romanin C, Matrougui K, Trebak M. Complex role of STIM1 in the activation of store-independent Orai1/3 channels The Journal of Cell Biology. 204: 2045OIA34. DOI: 10.1083/jcb.2045OIA34  0.325
2014 Chandrasekaran A, Flaherty NL, Trebak M, Andres Melendez J. Elucidation of the Key Redox-Dependent Calcium-Mediated Signaling Networks That Control the Senescence Associated Secretory and Inflammatory Phenotype Free Radical Biology and Medicine. 76: S30. DOI: 10.1016/J.Freeradbiomed.2014.10.438  0.307
2014 Stolwijk JA, Renken CW, Trebak M. Role of Calcium Signaling in Endothelial Barrier Function Biophysical Journal. 106: 719a-720a. DOI: 10.1016/J.Bpj.2013.11.3976  0.581
2014 Zhang X, Zhang W, González-Cobos J, Trebak M. Complex Function of Stim1 in the Activation of Store-Independent Orai Channels Biophysical Journal. 106: 314a. DOI: 10.1016/J.Bpj.2013.11.1817  0.854
2013 McCarthy DA, Clark RR, Bartling TR, Trebak M, Melendez JA. Redox control of the senescence regulator interleukin-1α and the secretory phenotype. The Journal of Biological Chemistry. 288: 32149-59. PMID 24062309 DOI: 10.1074/Jbc.M113.493841  0.393
2013 Rodríguez-Moyano M, Díaz I, Dionisio N, Zhang X, Avila-Medina J, Calderón-Sánchez E, Trebak M, Rosado JA, Ordóñez A, Smani T. Urotensin-II promotes vascular smooth muscle cell proliferation through store-operated calcium entry and EGFR transactivation. Cardiovascular Research. 100: 297-306. PMID 23933581 DOI: 10.1093/Cvr/Cvt196  0.601
2013 Ruhle B, Trebak M. Emerging roles for native Orai Ca2+ channels in cardiovascular disease. Current Topics in Membranes. 71: 209-35. PMID 23890117 DOI: 10.1016/B978-0-12-407870-3.00009-3  0.615
2013 Kassan M, Wecker A, Kadowitz P, Trebak M, Matrougui K. CD4 +CD25 +Foxp3 regulatoryTcells and vascular dysfunction in hypertension Journal of Hypertension. 31: 1939-1943. PMID 23881298 DOI: 10.1097/Hjh.0B013E328362Feb7  0.337
2013 Zhang X, González-Cobos JC, Schindl R, Muik M, Ruhle B, Motiani RK, Bisaillon JM, Zhang W, Fahrner M, Barroso M, Matrougui K, Romanin C, Trebak M. Mechanisms of STIM1 activation of store-independent leukotriene C4-regulated Ca2+ channels. Molecular and Cellular Biology. 33: 3715-23. PMID 23878392 DOI: 10.1128/Mcb.00554-13  0.838
2013 Motiani RK, Stolwijk JA, Newton RL, Zhang X, Trebak M. Emerging roles of Orai3 in pathophysiology. Channels (Austin, Tex.). 7: 392-401. PMID 23695829 DOI: 10.4161/Chan.24960  0.813
2013 Wood TR, Chow RY, Hanes CM, Zhang X, Kashiwagi K, Shirai Y, Trebak M, Loegering DJ, Saito N, Lennartz MR. PKC-ε pseudosubstrate and catalytic activity are necessary for membrane delivery during IgG-mediated phagocytosis. Journal of Leukocyte Biology. 94: 109-22. PMID 23670290 DOI: 10.1189/Jlb.1212634  0.349
2013 Motiani RK, Hyzinski-García MC, Zhang X, Henkel MM, Abdullaev IF, Kuo YH, Matrougui K, Mongin AA, Trebak M. STIM1 and Orai1 mediate CRAC channel activity and are essential for human glioblastoma invasion. PflüGers Archiv : European Journal of Physiology. 465: 1249-60. PMID 23515871 DOI: 10.1007/S00424-013-1254-8  0.809
2013 Shinde AV, Motiani RK, Zhang X, Abdullaev IF, Adam AP, González-Cobos JC, Zhang W, Matrougui K, Vincent PA, Trebak M. STIM1 controls endothelial barrier function independently of Orai1 and Ca2+ entry. Science Signaling. 6: ra18. PMID 23512989 DOI: 10.1126/Scisignal.2003425  0.834
2013 Merlet E, Atassi F, Motiani RK, Mougenot N, Jacquet A, Nadaud S, Capiod T, Trebak M, Lompré AM, Marchand A. miR-424/322 regulates vascular smooth muscle cell phenotype and neointimal formation in the rat. Cardiovascular Research. 98: 458-68. PMID 23447642 DOI: 10.1093/Cvr/Cvt045  0.702
2013 González-Cobos JC, Zhang X, Zhang W, Ruhle B, Motiani RK, Schindl R, Muik M, Spinelli AM, Bisaillon JM, Shinde AV, Fahrner M, Singer HA, Matrougui K, Barroso M, Romanin C, ... Trebak M, et al. Store-independent Orai1/3 channels activated by intracrine leukotriene C4: role in neointimal hyperplasia. Circulation Research. 112: 1013-25. PMID 23349245 DOI: 10.1161/Circresaha.111.300220  0.843
2013 Trebak M, Zhang W, Ruhle B, Henkel MM, González-Cobos JC, Motiani RK, Stolwijk JA, Newton RL, Zhang X. What role for store-operated Ca²⁺ entry in muscle? Microcirculation (New York, N.Y. : 1994). 20: 330-6. PMID 23312019 DOI: 10.1111/Micc.12042  0.805
2013 Motiani RK, Zhang X, Harmon KE, Keller RS, Matrougui K, Bennett JA, Trebak M. Orai3 is an estrogen receptor α-regulated Ca²⁺ channel that promotes tumorigenesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 63-75. PMID 22993197 DOI: 10.1096/Fj.12-213801  0.795
2013 Oulès B, Del Prete D, Greco B, Zhang X, Lauritzen I, Trebak M, Benfenati F, Checler F, Chami M. Leaky Ryanodine receptors increases Amyloid-beta load and induces memory impairments in Tg2576 mouse model of Alzheimer disease Molecular Neurodegeneration. 8: P54. DOI: 10.1186/1750-1326-8-S1-P54  0.386
2013 Jourd'heuil FL, Zhang W, Singer D, Halligan K, Alzawahara W, Singer HA, Trebak M, Jourd'heuil D. Cytokine Regulated Expression of the Hemoglobin Cytoglobin Regulates Nitric Oxide Synthase Cytotoxicity and Smooth Muscle Cell Survival during Vascular Remodeling Free Radical Biology and Medicine. 65: S73. DOI: 10.1016/J.Freeradbiomed.2013.10.564  0.39
2013 Flaherty NL, Stolwijk Ja, Trebak M, Andres Melendez J. Bacterial Antioxidants Restrict Immune Function by Limiting Actin Mobilization and Calcium Uptake Via the Transient Receptor Potential Ion Channels Free Radical Biology and Medicine. 65: S35. DOI: 10.1016/J.Freeradbiomed.2013.10.468  0.371
2012 Spinelli AM, González-Cobos JC, Zhang X, Motiani RK, Rowan S, Zhang W, Garrett J, Vincent PA, Matrougui K, Singer HA, Trebak M. Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration. Pflã¼Gers Archiv : European Journal of Physiology. 464: 481-92. PMID 23014880 DOI: 10.1007/S00424-012-1160-5  0.834
2012 Wang X, Hu G, Gao X, Wang Y, Zhang W, Harmon EY, Zhi X, Xu Z, Lennartz MR, Barroso M, Trebak M, Chen C, Zhou J. The induction of yes-associated protein expression after arterial injury is crucial for smooth muscle phenotypic modulation and neointima formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2662-9. PMID 22922963 DOI: 10.1161/Atvbaha.112.254730  0.407
2012 Oulès B, Del Prete D, Greco B, Zhang X, Lauritzen I, Sevalle J, Moreno S, Paterlini-Bréchot P, Trebak M, Checler F, Benfenati F, Chami M. Ryanodine receptor blockade reduces amyloid-β load and memory impairments in Tg2576 mouse model of Alzheimer disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11820-34. PMID 22915123 DOI: 10.1523/Jneurosci.0875-12.2012  0.473
2012 Galán M, Kassan M, Choi SK, Partyka M, Trebak M, Henrion D, Matrougui K. A novel role for epidermal growth factor receptor tyrosine kinase and its downstream endoplasmic reticulum stress in cardiac damage and microvascular dysfunction in type 1 diabetes mellitus. Hypertension. 60: 71-80. PMID 22665120 DOI: 10.1161/Hypertensionaha.112.192500  0.302
2012 Trebak M. STIM/Orai signalling complexes in vascular smooth muscle. The Journal of Physiology. 590: 4201-8. PMID 22641780 DOI: 10.1113/Jphysiol.2012.233353  0.636
2012 Kassan M, Galán M, Partyka M, Saifudeen Z, Henrion D, Trebak M, Matrougui K. Endoplasmic reticulum stress is involved in cardiac damage and vascular endothelial dysfunction in hypertensive mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1652-61. PMID 22539597 DOI: 10.1161/Atvbaha.112.249318  0.3
2012 Trebak M, Parekh AB. Ion channels in patho-physiology. The Journal of Physiology. 590: 1347. PMID 22422116 DOI: 10.1113/Jphysiol.2012.230219  0.438
2012 Choi SK, Galán M, Partyka M, Trebak M, Belmadani S, Matrougui K. Chronic inhibition of epidermal growth factor receptor tyrosine kinase and extracellular signal-regulated kinases 1 and 2 (ERK1/2) augments vascular response to limb ischemia in type 2 diabetic mice. The American Journal of Pathology. 180: 410-8. PMID 22067908 DOI: 10.1016/J.Ajpath.2011.09.016  0.321
2012 Jourd'heuil FL, Zhang W, Halligan K, McKellar K, Alzawahara W, Singer HA, Trebak M, Jourd'heuil D. Loss of the Nitric Oxide Dioxygenase Cytoglobin Exacerbates Smooth Muscle Apoptosis and Inhibits Restenosis during Vascular Injury Free Radical Biology and Medicine. 53: S165. DOI: 10.1016/J.Freeradbiomed.2012.10.451  0.336
2011 Trebak M. PLC: Johnny-come-lately to ORAI and the ups and downs of calcium signalling. The Journal of Physiology. 589: 5337-8. PMID 22086246 DOI: 10.1113/Jphysiol.2011.220517  0.585
2011 Balghi H, Robert R, Rappaz B, Zhang X, Wohlhuter-Haddad A, Evagelidis A, Luo Y, Goepp J, Ferraro P, Roméo P, Trebak M, Wiseman PW, Thomas DY, Hanrahan JW. Enhanced Ca2+ entry due to Orai1 plasma membrane insertion increases IL-8 secretion by cystic fibrosis airways. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 4274-91. PMID 21873556 DOI: 10.1096/Fj.11-187682  0.461
2011 Kassan M, Galan M, Partyka M, Trebak M, Matrougui K. Interleukin-10 released by CD4(+)CD25(+) natural regulatory T cells improves microvascular endothelial function through inhibition of NADPH oxidase activity in hypertensive mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2534-42. PMID 21817097 DOI: 10.1161/Atvbaha.111.233262  0.303
2011 Zhang W, Trebak M. STIM1 and Orai1: novel targets for vascular diseases? Science China. Life Sciences. 54: 780-5. PMID 21786201 DOI: 10.1007/S11427-011-4206-6  0.588
2011 Zhang W, Halligan KE, Zhang X, Bisaillon JM, Gonzalez-Cobos JC, Motiani RK, Hu G, Vincent PA, Zhou J, Barroso M, Singer HA, Matrougui K, Trebak M. Orai1-mediated I (CRAC) is essential for neointima formation after vascular injury. Circulation Research. 109: 534-42. PMID 21737791 DOI: 10.1161/Circresaha.111.246777  0.804
2011 Trebak M. Review ofTransient Receptor Potential Channels Channels. 5: 188-190. DOI: 10.4161/Chan.5.2.15312  0.377
2010 Gonzalez-Cobos JC, Trebak M. TRPC channels in smooth muscle cells. Frontiers in Bioscience (Landmark Edition). 15: 1023-39. PMID 20515740 DOI: 10.2741/3660  0.816
2010 Wang Z, Ginnan R, Abdullaev IF, Trebak M, Vincent PA, Singer HA. Calcium/Calmodulin-dependent protein kinase II delta 6 (CaMKIIdelta6) and RhoA involvement in thrombin-induced endothelial barrier dysfunction. The Journal of Biological Chemistry. 285: 21303-12. PMID 20442409 DOI: 10.1074/Jbc.M110.120790  0.49
2010 Motiani RK, Abdullaev IF, Trebak M. A novel native store-operated calcium channel encoded by Orai3: selective requirement of Orai3 versus Orai1 in estrogen receptor-positive versus estrogen receptor-negative breast cancer cells. The Journal of Biological Chemistry. 285: 19173-83. PMID 20395295 DOI: 10.1074/Jbc.M110.102582  0.776
2010 Bisaillon JM, Motiani RK, Gonzalez-Cobos JC, Potier M, Halligan KE, Alzawahra WF, Barroso M, Singer HA, Jourd'heuil D, Trebak M. Essential role for STIM1/Orai1-mediated calcium influx in PDGF-induced smooth muscle migration American Journal of Physiology - Cell Physiology. 298: C993-C1005. PMID 20107038 DOI: 10.1152/Ajpcell.00325.2009  0.847
2010 Trebak M. The puzzling role of TRPC3 channels in motor coordination. PflüGers Archiv : European Journal of Physiology. 459: 369-75. PMID 19823866 DOI: 10.1007/S00424-009-0740-5  0.395
2010 Trebak M, Ginnan R, Singer HA, Jourd'heuil D. Interplay between calcium and reactive oxygen/nitrogen species: an essential paradigm for vascular smooth muscle signaling. Antioxidants & Redox Signaling. 12: 657-74. PMID 19719386 DOI: 10.1089/Ars.2009.2842  0.612
2009 Trebak M. STIM1/Orai1, ICRAC, and endothelial SOC. Circulation Research. 104: e56-7. PMID 19423858 DOI: 10.1161/Circresaha.109.196105  0.637
2009 Potier M, Gonzalez JC, Motiani RK, Abdullaev IF, Bisaillon JM, Singer HA, Trebak M. Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: Role in proliferation and migration Faseb Journal. 23: 2425-2437. PMID 19364762 DOI: 10.1096/Fj.09-131128  0.816
2009 Trebak M, Lemonnier L, DeHaven WI, Wedel BJ, Bird GS, Putney JW. Complex functions of phosphatidylinositol 4,5-bisphosphate in regulation of TRPC5 cation channels. PflüGers Archiv : European Journal of Physiology. 457: 757-69. PMID 18665391 DOI: 10.1007/S00424-008-0550-1  0.499
2009 Abdullaev IF, Bisaillon JM, Potier M, Gonzalez JC, Motiani RK, Trebak M. Stim1 and Orai1 Mediate CRAC Currents and Store-Operated Calcium Entry Necessary for Endothelial Cell Proliferation Biophysical Journal. 96: 670a. DOI: 10.1016/j.bpj.2008.12.3542  0.705
2008 Zayed N, Afif H, Chabane N, Mfuna-Endam L, Benderdour M, Martel-Pelletier J, Pelletier JP, Motiani RK, Trebak M, Duval N, Fahmi H. Inhibition of interleukin-1beta-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2. Arthritis and Rheumatism. 58: 3530-40. PMID 18975308 DOI: 10.1002/Art.23958  0.645
2008 Abdullaev IF, Bisaillon JM, Potier M, Gonzalez JC, Motiani RK, Trebak M. Stim1 and orai1 mediate crac currents and store-operated calcium entry important for endothelial cell proliferation Circulation Research. 103: 1289-1299. PMID 18845811 DOI: 10.1161/01.Res.0000338496.95579.56  0.815
2008 Potier M, Trebak M. New developments in the signaling mechanisms of the store-operated calcium entry pathway Pflugers Archiv European Journal of Physiology. 457: 405-415. PMID 18536932 DOI: 10.1007/S00424-008-0533-2  0.611
2008 House SJ, Potier M, Bisaillon J, Singer HA, Trebak M. The non-excitable smooth muscle: Calcium signaling and phenotypic switching during vascular disease Pflugers Archiv European Journal of Physiology. 456: 769-785. PMID 18365243 DOI: 10.1007/S00424-008-0491-8  0.645
2008 Lemonnier L, Trebak M, Putney JW. Complex regulation of the TRPC3, 6 and 7 channel subfamily by diacylglycerol and phosphatidylinositol-4,5-bisphosphate. Cell Calcium. 43: 506-14. PMID 17942152 DOI: 10.1016/J.Ceca.2007.09.001  0.464
2007 Trebak M, Lemonnier L, Smyth JT, Vazquez G, Putney JW. Phospholipase C-coupled receptors and activation of TRPC channels. Handbook of Experimental Pharmacology. 593-614. PMID 17217081 DOI: 10.1007/978-3-540-34891-7_35  0.461
2006 Smyth JT, Dehaven WI, Jones BF, Mercer JC, Trebak M, Vazquez G, Putney JW. Emerging perspectives in store-operated Ca2+ entry: roles of Orai, Stim and TRP. Biochimica Et Biophysica Acta. 1763: 1147-60. PMID 17034882 DOI: 10.1016/J.Bbamcr.2006.08.050  0.58
2006 Trebak M. Canonical transient receptor potential channels in disease: targets for novel drug therapy? Drug Discovery Today. 11: 924-30. PMID 16997143 DOI: 10.1016/J.Drudis.2006.08.002  0.456
2006 Lemonnier L, Trebak M, Lievremont JP, Bird GS, Putney JW. Protection of TRPC7 cation channels from calcium inhibition by closely associated SERCA pumps. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 503-5. PMID 16401641 DOI: 10.1096/Fj.05-4714Fje  0.554
2005 Lievremont JP, Numaga T, Vazquez G, Lemonnier L, Hara Y, Mori E, Trebak M, Moss SE, Bird GS, Mori Y, Putney JW. The role of canonical transient receptor potential 7 in B-cell receptor-activated channels. The Journal of Biological Chemistry. 280: 35346-51. PMID 16123040 DOI: 10.1074/Jbc.M507606200  0.581
2005 Trebak M, Hempel N, Wedel BJ, Smyth JT, Bird GS, Putney JW. Negative regulation of TRPC3 channels by protein kinase C-mediated phosphorylation of serine 712. Molecular Pharmacology. 67: 558-63. PMID 15533987 DOI: 10.1124/Mol.104.007252  0.45
2004 Vazquez G, Wedel BJ, Aziz O, Trebak M, Putney JW. The mammalian TRPC cation channels. Biochimica Et Biophysica Acta. 1742: 21-36. PMID 15590053 DOI: 10.1016/J.Bbamcr.2004.08.015  0.474
2004 Putney JW, Trebak M, Vazquez G, Wedel B, Bird GS. Signalling mechanisms for TRPC3 channels. Novartis Foundation Symposium. 258: 123-33; discussion 1. PMID 15104179 DOI: 10.1002/0470862580.Ch9  0.491
2004 Bird GS, Aziz O, Lievremont JP, Wedel BJ, Trebak M, Vazquez G, Putney JW. Mechanisms of phospholipase C-regulated calcium entry. Current Molecular Medicine. 4: 291-301. PMID 15101686 DOI: 10.2174/1566524043360681  0.581
2003 Trebak M, Vazquez G, Bird GS, Putney JW. The TRPC3/6/7 subfamily of cation channels. Cell Calcium. 33: 451-61. PMID 12765690 DOI: 10.1016/S0143-4160(03)00056-3  0.514
2003 Vazquez G, Wedel BJ, Trebak M, St John Bird G, Putney JW. Expression level of the canonical transient receptor potential 3 (TRPC3) channel determines its mechanism of activation. The Journal of Biological Chemistry. 278: 21649-54. PMID 12686562 DOI: 10.1074/Jbc.M302162200  0.523
2003 Trebak M, St J Bird G, McKay RR, Birnbaumer L, Putney JW. Signaling mechanism for receptor-activated canonical transient receptor potential 3 (TRPC3) channels. The Journal of Biological Chemistry. 278: 16244-52. PMID 12606542 DOI: 10.1074/Jbc.M300544200  0.45
2002 Trebak M, Bird GS, McKay RR, Putney JW. Comparison of human TRPC3 channels in receptor-activated and store-operated modes. Differential sensitivity to channel blockers suggests fundamental differences in channel composition. The Journal of Biological Chemistry. 277: 21617-23. PMID 11943785 DOI: 10.1074/Jbc.M202549200  0.5
2001 Rahmouni S, Aandahl EM, Trebak M, Boniver J, Taskén K, Moutschen M. Increased cAMP levels and protein kinase (PKA) type I activation in CD4+ T cells and B cells contribute to retrovirus-induced immunodeficiency of mice (MAIDS): a useful in vivo model for drug testing. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1466-8. PMID 11387259 DOI: 10.1096/Fj.00-0813Fje  0.325
1998 Trebak M, Lambert CA, Rahmouni S, Debrus S, Defresne MP, Regnier D, Boniver J, Moutschen M. Decreased protein levels of the c-Cbl protooncogene in murine AIDS. Cellular Immunology. 188: 151-7. PMID 9756645 DOI: 10.1006/Cimm.1998.1348  0.355
1997 Greimers R, Trebak M, Moutschen M, Jacobs N, Boniver J. Improved four-color flow cytometry method using fluo-3 and triple immunofluorescence for analysis of intracellular calcium ion ([Ca2+]i) fluxes among mouse lymph node B- and T-lymphocyte subsets. Cytometry. 23: 205-17. PMID 8974866 DOI: 10.1002/(Sici)1097-0320(19960301)23:3<205::Aid-Cyto4>3.0.Co;2-H  0.369
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