| Year |
Citation |
Score |
| 2022 |
de Faria Lopes L, Jandova J, Justiniano R, Perer J, Baptista MS, Wondrak GT. The Glycolysis-Derived α-Dicarbonyl Metabolite Methylglyoxal is a UVA-Photosensitizer Causing the Photooxidative Elimination of Hacat Keratinocytes with Induction of Oxidative and Proteotoxic Stress Response Gene Expression. Photochemistry and Photobiology. PMID 36109156 DOI: 10.1111/php.13717 |
0.367 |
|
| 2022 |
Jandova J, Park SL, Corenblum MJ, Madhavan L, Snell JA, Rounds L, Wondrak GT. Mefloquine induces ER stress and apoptosis in BRAFi-resistant A375-BRAF /NRAS malignant melanoma cells targeting intracranial tumors in a bioluminescent murine model. Molecular Carcinogenesis. PMID 35417045 DOI: 10.1002/mc.23407 |
0.381 |
|
| 2021 |
Jandova J, Snell J, Hua A, Dickinson S, Fimbres J, Wondrak GT. Topical hypochlorous acid (HOCl) blocks inflammatory gene expression and tumorigenic progression in UV-exposed SKH-1 high risk mouse skin. Redox Biology. 45: 102042. PMID 34144392 DOI: 10.1016/j.redox.2021.102042 |
0.342 |
|
| 2021 |
Jandova J, Hua AB, Fimbres J, Wondrak GT. Deuterium Oxide (DO) Induces Early Stress Response Gene Expression and Impairs Growth and Metastasis of Experimental Malignant Melanoma. Cancers. 13. PMID 33546433 DOI: 10.3390/cancers13040605 |
0.439 |
|
| 2020 |
Schmidlin CJ, Rojo de la Vega M, Perer J, Zhang DD, Wondrak GT. Activation of NRF2 by topical apocarotenoid treatment mitigates radiation-induced dermatitis. Redox Biology. 37: 101714. PMID 32927319 DOI: 10.1016/J.Redox.2020.101714 |
0.45 |
|
| 2020 |
Justiniano R, de Faria Lopes L, Perer J, Hua A, Park SL, Jandova J, Baptista MS, Wondrak GT. The Endogenous Tryptophan-derived Photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) Is a Nanomolar Photosensitizer That Can Be Harnessed for the Photodynamic Elimination of Skin Cancer Cells in Vitro and in Vivo. Photochemistry and Photobiology. PMID 32767762 DOI: 10.1111/Php.13321 |
0.531 |
|
| 2020 |
Perer J, Jandova J, Fimbres J, Jennings EQ, Galligan JJ, Hua A, Wondrak GT. The sunless tanning agent dihydroxyacetone induces stress response gene expression and signaling in cultured human keratinocytes and reconstructed epidermis. Redox Biology. 36: 101594. PMID 32506039 DOI: 10.1016/J.Redox.2020.101594 |
0.491 |
|
| 2020 |
Jandova J, Perer J, Hua A, Snell JA, Wondrak GT. Genetic Target Modulation Employing CRISPR/Cas9 Identifies Glyoxalase 1 as a Novel Molecular Determinant of Invasion and Metastasis in A375 Human Malignant Melanoma Cells In Vitro and In Vivo. Cancers. 12. PMID 32466621 DOI: 10.3390/Cancers12061369 |
0.439 |
|
| 2020 |
Jandova J, Hua A, Dickinson SE, Shakya A, Wondrak GT. 641 The cutaneous response to solar UV radiation is attenuated by chlorination stress originating from swimming pool disinfectants Journal of Investigative Dermatology. 140. DOI: 10.1016/J.Jid.2020.03.652 |
0.333 |
|
| 2020 |
Perer J, Jandova J, Fimbres J, Jennings E, Galligan J, Hua A, Wondrak GT. 609 The topical tanning agent dihydroxyacetone induces stress response gene expression and signaling in human reconstructed epidermis and SKH1 hairless mouse skin Journal of Investigative Dermatology. 140. DOI: 10.1016/J.Jid.2020.03.619 |
0.45 |
|
| 2019 |
Hua AB, Justiniano R, Perer J, Park SL, Li H, Cabello CM, Wondrak GT. Repurposing the Electron Transfer Reactant Phenazine Methosulfate (PMS) for the Apoptotic Elimination of Malignant Melanoma Cells through Induction of Lethal Oxidative and Mitochondriotoxic Stress. Cancers. 11. PMID 31035569 DOI: 10.3390/Cancers11050590 |
0.805 |
|
| 2019 |
Dickinson SE, Wondrak GT. TLR4 in skin cancer: From molecular mechanisms to clinical interventions. Molecular Carcinogenesis. PMID 31020719 DOI: 10.1002/Mc.23016 |
0.39 |
|
| 2019 |
Perer J, Justiniano R, Hua A, Wondrak GT. Abstract 2665: Zinc dysregulation as an emerging molecular target in epithelial cancers Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2665 |
0.305 |
|
| 2018 |
Rojo de la Vega M, Zhang DD, Wondrak GT. Topical Bixin Confers NRF2-Dependent Protection Against Photodamage and Hair Graying in Mouse Skin. Frontiers in Pharmacology. 9: 287. PMID 29636694 DOI: 10.3389/Fphar.2018.00287 |
0.444 |
|
| 2018 |
Blohm-Mangone K, Burkett NB, Tahsin S, Myrdal PB, Aodah A, Ho B, Janda J, McComas M, Saboda K, Roe DJ, Dong Z, Bode AM, Petricoin EF, Calvert VS, Curiel-Lewandrowski C, ... ... Wondrak GT, et al. Pharmacological TLR4 antagonism using topical resatorvid blocks solar UV-induced skin tumorigenesis in SKH-1 mice. Cancer Prevention Research (Philadelphia, Pa.). PMID 29437671 DOI: 10.1158/1940-6207.Capr-17-0349 |
0.448 |
|
| 2017 |
Teves JMY, Bhargava V, Kirwan KR, Corenblum MJ, Justiniano R, Wondrak GT, Anandhan A, Flores AJ, Schipper DA, Khalpey Z, Sligh JE, Curiel-Lewandrowski C, Sherman SJ, Madhavan L. Parkinson's Disease Skin Fibroblasts Display Signature Alterations in Growth, Redox Homeostasis, Mitochondrial Function, and Autophagy. Frontiers in Neuroscience. 11: 737. PMID 29379409 DOI: 10.3389/Fnins.2017.00737 |
0.32 |
|
| 2017 |
Rojo de la Vega M, Krajisnik A, Zhang DD, Wondrak GT. Targeting NRF2 for Improved Skin Barrier Function and Photoprotection: Focus on the Achiote-Derived Apocarotenoid Bixin. Nutrients. 9. PMID 29258247 DOI: 10.3390/Nu9121371 |
0.458 |
|
| 2017 |
Dickinson SE, Wondrak GT. TLR4-directed Molecular Strategies Targeting Skin Photodamage and Carcinogenesis. Current Medicinal Chemistry. PMID 28847267 DOI: 10.2174/0929867324666170828125328 |
0.386 |
|
| 2017 |
Justiniano R, Perer J, Hua A, Fazel M, Krajisnik A, Cabello CM, Wondrak GT. A Topical Zinc Ionophore Blocks Tumorigenic Progression in UV-exposed SKH-1 High Risk Mouse Skin. Photochemistry and Photobiology. PMID 28503778 DOI: 10.1111/Php.12794 |
0.788 |
|
| 2017 |
Justiniano R, Williams JD, Perer J, Hua A, Lesson J, Park SL, Wondrak GT. The B6 -vitamer Pyridoxal is a Sensitizer of UVA-induced Genotoxic Stress in Human Primary Keratinocytes and Reconstructed Epidermis. Photochemistry and Photobiology. PMID 28083878 DOI: 10.1111/Php.12720 |
0.527 |
|
| 2017 |
Dickinson SE, Blohm-Mangone K, Burkett NB, Tahsin S, Myrdal PB, Karlage KL, Janda J, Saboda K, Roe DJ, Dong Z, Bode AM, Petricoin EF, Calvert VS, Curiel-Lewandrowski C, Alberts DS, ... Wondrak GT, et al. Abstract 2244: Pharmacological TLR4 antagonism using topical resatorvid blocks solar UV-induced skin tumorigenesis in SKH-1 mice Cancer Research. 77: 2244-2244. DOI: 10.1158/1538-7445.Am2017-2244 |
0.315 |
|
| 2017 |
Dickinson S, Blohm-Mangone K, Burkett N, Tahsin S, Myrdal P, Aodah A, Janda J, Saboda K, Dong Z, Bode A, Petricoin E, Calvert V, Curiel-Lewandrowski C, Wondrak G. 764 A novel strategy for topical photochemoprevention: Pharmacological TLR4 antagonism blocks non-melanoma skin cancer Journal of Investigative Dermatology. 137: S131. DOI: 10.1016/J.Jid.2017.02.788 |
0.356 |
|
| 2017 |
Steinfass T, Park S, Justiniano R, Hua A, Wondrak G. 722 Repurposing the clinical anti-malarial quinacrine for chaperone-mediated autophagy (CMA)-directed anti-melanoma intervention Journal of Investigative Dermatology. 137: S124. DOI: 10.1016/J.Jid.2017.02.745 |
0.321 |
|
| 2017 |
de la Vega MR, Wondrak G, Zhang D. The Apocarotenoid Bixin Protects Mouse Skin against UV-induced Damage in an NRF2-dependent Manner Free Radical Biology and Medicine. 112: 194. DOI: 10.1016/J.Freeradbiomed.2017.10.306 |
0.436 |
|
| 2016 |
Janda J, Burkett N, Blohm-Mangone K, Huang V, Curiel-Lewandrowski C, Alberts DS, Petricoin EF, Calvert VS, Einspahr J, Dong Z, Bode AM, Wondrak GT, Dickinson SE. Resatorvid-based Pharmacological Antagonism of Cutaneous TLR4 Blocks UV-induced NF-κB and AP-1 Signaling in Keratinocytes and Mouse Skin. Photochemistry and Photobiology. PMID 27859308 DOI: 10.1111/Php.12659 |
0.408 |
|
| 2016 |
Tao S, Rojo de la Vega M, Quijada H, Wondrak GT, Wang T, Garcia JG, Zhang DD. Bixin protects mice against ventilation-induced lung injury in an NRF2-dependent manner. Scientific Reports. 6: 18760. PMID 26729554 DOI: 10.1038/Srep18760 |
0.311 |
|
| 2016 |
Rojo de la Vega M, Tao S, Park S, Zhang D, Wondrak G. The achiote-derived apocarotenoid bixin protects skin against environmental insults through NRF2-dependent activation of the epidermal antioxidant response Toxicology Letters. 259: S196-S197. DOI: 10.1016/J.Toxlet.2016.07.468 |
0.402 |
|
| 2016 |
Park S, Steinfass T, Hua A, Wondrak G. 554 Repurposing a clinical antimalarial for the therapeutic induction of lethal ER stress targeting BRAF-kinase inhibitor-resistant malignant melanoma Journal of Investigative Dermatology. 136: S98. DOI: 10.1016/J.Jid.2016.02.592 |
0.389 |
|
| 2016 |
Hua A, Park S, Justiniano R, Fazel M, Cabello C, Wondrak G. 551 Targeting the redox vulnerability of V600E BRAF-mutated malignant melanoma cells using the electron transfer reactant PMS (phenazine methosulfate) as a mitochondria-directed chemotherapeutic Journal of Investigative Dermatology. 136: S97. DOI: 10.1016/J.Jid.2016.02.589 |
0.736 |
|
| 2016 |
Justiniano R, Cabello C, Seanez C, Fazel M, Wondrak G. 550 The topical OTC antimicrobial zinc pyrithione (ZnPT) suppresses tumorigenic progression in a SKH-1 mouse model of solar UV-induced skin carcinogenesis Journal of Investigative Dermatology. 136: S97. DOI: 10.1016/J.Jid.2016.02.588 |
0.737 |
|
| 2016 |
Janda J, Blohm-Mangone K, Burkett N, Einspahr J, Alberts D, Dong Z, Bode A, Curiel-Lewandrowski C, Wondrak G, Dickinson S. 085 TLR4 as a novel molecular target for non-melanoma skin cancer prevention Journal of Investigative Dermatology. 136: S15. DOI: 10.1016/J.Jid.2016.02.111 |
0.392 |
|
| 2015 |
Long M, Rojo de la Vega M, Wen Q, Bharara M, Jiang T, Zhang R, Zhou S, Wong PK, Wondrak GT, Zheng H, Zhang DD. An essential role of NRF2 in diabetic wound healing. Diabetes. PMID 26718502 DOI: 10.2337/Db15-0564 |
0.373 |
|
| 2015 |
Tao S, Park SL, de la Vega MR, Zhang DD, Wondrak GT. Systemic administration of the apocarotenoid bixin protects skin against solar UV-induced damage through activation of NRF2. Free Radical Biology & Medicine. PMID 26456052 DOI: 10.1016/J.Freeradbiomed.2015.08.028 |
0.402 |
|
| 2015 |
Long M, Tao S, Rojo de la Vega M, Jiang T, Wen Q, Park SL, Zhang DD, Wondrak GT. Nrf2-dependent suppression of azoxymethane/dextran sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde. Cancer Prevention Research (Philadelphia, Pa.). 8: 444-54. PMID 25712056 DOI: 10.1158/1940-6207.Capr-14-0359 |
0.365 |
|
| 2015 |
Davis AL, Qiao S, Lesson JL, Rojo de la Vega M, Park SL, Seanez CM, Gokhale V, Cabello CM, Wondrak GT. The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cells. The Journal of Biological Chemistry. 290: 1623-38. PMID 25477506 DOI: 10.1074/Jbc.M114.592626 |
0.841 |
|
| 2015 |
Park SL, Justiniano R, Williams JD, Cabello CM, Qiao S, Wondrak GT. The Tryptophan-Derived Endogenous Aryl Hydrocarbon Receptor Ligand 6-Formylindolo[3,2-b]Carbazole Is a Nanomolar UVA Photosensitizer in Epidermal Keratinocytes. The Journal of Investigative Dermatology. 135: 1649-58. PMID 25431849 DOI: 10.1038/Jid.2014.503 |
0.826 |
|
| 2015 |
Justiniano R, Park SL, Williams JD, Wieland DR, Wondrak GT. The Endogenous Tryptophan-Derived Photoproduct and AhR Agonist 6-Formylindolo[3,2-B]carbazole (FICZ) Is a Nanomolar Cutaneous Photosensitizer That Can Be Harnessed for the Oxidative Elimination of Skin Cancer Cells in Vitro and in Vivo Free Radical Biology and Medicine. 87: S113. DOI: 10.1016/J.Freeradbiomed.2015.10.298 |
0.422 |
|
| 2015 |
Hua AB, Park SL, Justiniano R, Fazel M, Cabello CM, Wondrak GT. Repurposing the Electron Transfer Reactant PMS (Phenazine Methosulfate) as an Experimental Redox Chemotherapeutic for the Superoxide-Dependent Apoptotic Elimination of Malignant Cells Free Radical Biology and Medicine. 87: S98-S99. DOI: 10.1016/J.Freeradbiomed.2015.10.262 |
0.731 |
|
| 2015 |
Park SL, Steinfass T, Wondrak GT. The Clinical Antimalarial Mefloquine Induces Lethal ER and Oxidative Stress Targeting BRAF-Kinase Inhibitor-Resistant Malignant Melanoma Cells Free Radical Biology and Medicine. 87: S70-S71. DOI: 10.1016/J.Freeradbiomed.2015.10.185 |
0.451 |
|
| 2015 |
Wondrak G. Redox-directed interventions targeting skin photodamage Free Radical Biology and Medicine. 86: S6. DOI: 10.1016/J.Freeradbiomed.2015.07.034 |
0.374 |
|
| 2014 |
Shen T, Chen XM, Harder B, Long M, Wang XN, Lou HX, Wondrak GT, Ren DM, Zhang DD. Plant extracts of the family Lauraceae: a potential resource for chemopreventive agents that activate the nuclear factor-erythroid 2-related factor 2/antioxidant response element pathway. Planta Medica. 80: 426-34. PMID 24585092 DOI: 10.1055/S-0034-1368197 |
0.457 |
|
| 2014 |
Williams JD, Bermudez Y, Park SL, Stratton SP, Uchida K, Hurst CA, Wondrak GT. Malondialdehyde-derived epitopes in human skin result from acute exposure to solar UV and occur in nonmelanoma skin cancer tissue. Journal of Photochemistry and Photobiology. B, Biology. 132: 56-65. PMID 24584085 DOI: 10.1016/J.Jphotobiol.2014.01.019 |
0.424 |
|
| 2014 |
Davis AL, Qiao S, Justiniano R, de la Vega MR, Wondrak GT. Redox-Directed Suppression of Malignant Cell Invasion in a Three-Dimensional Skin Reconstruct Model of Metastatic Melanoma Free Radical Biology and Medicine. 76: S80. DOI: 10.1016/J.Freeradbiomed.2014.10.283 |
0.76 |
|
| 2014 |
Williams JD, Bermudez Y, Lian F, Uchida K, Park SL, Wondrak GT. Acute Solar UV Exposure Generates Photodamage-Associated Protein Epitopes in Healthy Human Skin: Implications for Cutaneous Tumorigenesis Free Radical Biology and Medicine. 76: S135-S136. DOI: 10.1016/J.Freeradbiomed.2014.10.223 |
0.349 |
|
| 2013 |
Tao S, Justiniano R, Zhang DD, Wondrak GT. The Nrf2-inducers tanshinone I and dihydrotanshinone protect human skin cells and reconstructed human skin against solar simulated UV. Redox Biology. 1: 532-41. PMID 24273736 DOI: 10.1016/J.Redox.2013.10.004 |
0.45 |
|
| 2013 |
Qiao S, Tao S, Rojo de la Vega M, Park SL, Vonderfecht AA, Jacobs SL, Zhang DD, Wondrak GT. The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death. Autophagy. 9: 2087-102. PMID 24113242 DOI: 10.4161/Auto.26506 |
0.808 |
|
| 2013 |
Lamore SD, Wondrak GT. UVA causes dual inactivation of cathepsin B and L underlying lysosomal dysfunction in human dermal fibroblasts. Journal of Photochemistry and Photobiology. B, Biology. 123: 1-12. PMID 23603447 DOI: 10.1016/J.Jphotobiol.2013.03.007 |
0.76 |
|
| 2013 |
Davis AL, Cabello CM, Qiao S, Azimian S, Wondrak GT. Phenotypic identification of the redox dye methylene blue as an antagonist of heat shock response gene expression in metastatic melanoma cells. International Journal of Molecular Sciences. 14: 4185-202. PMID 23429201 DOI: 10.3390/Ijms14024185 |
0.805 |
|
| 2013 |
Tao S, Zheng Y, Lau A, Jaramillo MC, Chau BT, Lantz RC, Wong PK, Wondrak GT, Zhang DD. Tanshinone I activates the Nrf2-dependent antioxidant response and protects against As(III)-induced lung inflammation in vitro and in vivo. Antioxidants & Redox Signaling. 19: 1647-61. PMID 23394605 DOI: 10.1089/Ars.2012.5117 |
0.39 |
|
| 2012 |
Qiao S, Cabello CM, Lamore SD, Lesson JL, Wondrak GT. D-Penicillamine targets metastatic melanoma cells with induction of the unfolded protein response (UPR) and Noxa (PMAIP1)-dependent mitochondrial apoptosis. Apoptosis : An International Journal On Programmed Cell Death. 17: 1079-94. PMID 22843330 DOI: 10.1007/S10495-012-0746-X |
0.821 |
|
| 2012 |
Qiao S, Lamore SD, Cabello CM, Lesson JL, Muñoz-Rodriguez JL, Wondrak GT. Thiostrepton is an inducer of oxidative and proteotoxic stress that impairs viability of human melanoma cells but not primary melanocytes. Biochemical Pharmacology. 83: 1229-40. PMID 22321511 DOI: 10.1016/J.Bcp.2012.01.027 |
0.833 |
|
| 2012 |
Wondrak GT, Jacobson EL. Vitamin B6: beyond coenzyme functions. Sub-Cellular Biochemistry. 56: 291-300. PMID 22116705 DOI: 10.1007/978-94-007-2199-9_15 |
0.302 |
|
| 2012 |
Lamore SD, Wondrak GT. Autophagic-lysosomal dysregulation downstream of cathepsin B inactivation in human skin fibroblasts exposed to UVA. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 11: 163-72. PMID 21773629 DOI: 10.1039/C1Pp05131H |
0.751 |
|
| 2012 |
Cabello CM, Lamore SD, Bair WB, Qiao S, Azimian S, Lesson JL, Wondrak GT. The redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of NOXA-dependent apoptosis. Investigational New Drugs. 30: 1289-301. PMID 21547369 DOI: 10.1007/S10637-011-9676-7 |
0.832 |
|
| 2012 |
Davis AL, Qiao S, Cabello CM, Lesson JL, Wondrak GT. Identification of Aurin as an Experimental Chemotherapeutic for the Pharmacological Induction of Proteotoxic Stress Targeting Metastatic Melanoma Free Radical Biology and Medicine. 53: S105-S106. DOI: 10.1016/J.Freeradbiomed.2012.10.251 |
0.802 |
|
| 2012 |
Qiao S, Wondrak GT. Redox Chemotherapeutic Intervention Targeting Proliferative Dysregulation in Multiple Myeloma Free Radical Biology and Medicine. 53: S49. DOI: 10.1016/J.Freeradbiomed.2012.10.130 |
0.736 |
|
| 2011 |
Lamore SD, Wondrak GT. Zinc pyrithione impairs zinc homeostasis and upregulates stress response gene expression in reconstructed human epidermis. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 24: 875-90. PMID 21424779 DOI: 10.1007/S10534-011-9441-6 |
0.795 |
|
| 2011 |
Cabello CM, Lamore SD, Bair WB, Davis AL, Azimian SM, Wondrak GT. DCPIP (2,6-dichlorophenolindophenol) as a genotype-directed redox chemotherapeutic targeting NQO1*2 breast carcinoma. Free Radical Research. 45: 276-92. PMID 21034357 DOI: 10.3109/10715762.2010.526766 |
0.82 |
|
| 2010 |
Lamore SD, Qiao S, Horn D, Wondrak GT. Proteomic identification of cathepsin B and nucleophosmin as novel UVA-targets in human skin fibroblasts. Photochemistry and Photobiology. 86: 1307-17. PMID 20946361 DOI: 10.1111/J.1751-1097.2010.00818.X |
0.816 |
|
| 2010 |
Lamore SD, Azimian S, Horn D, Anglin BL, Uchida K, Cabello CM, Wondrak GT. The malondialdehyde-derived fluorophore DHP-lysine is a potent sensitizer of UVA-induced photooxidative stress in human skin cells. Journal of Photochemistry and Photobiology. B, Biology. 101: 251-64. PMID 20724175 DOI: 10.1016/J.Jphotobiol.2010.07.010 |
0.83 |
|
| 2010 |
Wondrak GT, Villeneuve NF, Lamore SD, Bause AS, Jiang T, Zhang DD. The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells. Molecules (Basel, Switzerland). 15: 3338-55. PMID 20657484 DOI: 10.3390/Molecules15053338 |
0.75 |
|
| 2010 |
Papoutsis AJ, Lamore SD, Wondrak GT, Selmin OI, Romagnolo DF. Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells. The Journal of Nutrition. 140: 1607-14. PMID 20631324 DOI: 10.3945/Jn.110.123422 |
0.719 |
|
| 2010 |
Lamore SD, Cabello CM, Wondrak GT. HMGB1-directed drug discovery targeting cutaneous inflammatory dysregulation. Current Drug Metabolism. 11: 250-65. PMID 20406187 DOI: 10.2174/138920010791196337 |
0.781 |
|
| 2010 |
Bair WB, Cabello CM, Uchida K, Bause AS, Wondrak GT. GLO1 overexpression in human malignant melanoma. Melanoma Research. 20: 85-96. PMID 20093988 DOI: 10.1097/Cmr.0B013E3283364903 |
0.795 |
|
| 2010 |
Lamore SD, Cabello CM, Wondrak GT. The topical antimicrobial zinc pyrithione is a heat shock response inducer that causes DNA damage and PARP-dependent energy crisis in human skin cells. Cell Stress & Chaperones. 15: 309-22. PMID 19809895 DOI: 10.1007/S12192-009-0145-6 |
0.818 |
|
| 2010 |
Cabello CM, Qiao S, Bair WB, Davis AL, Lesson JL, Wondrak GT. GLO1 Downregulation in Human Renal Cell Carcinoma Enables Targeted Chemotherapeutic Intervention Using Methylglyoxal as Cytotoxic Heat Shock Inducer Free Radical Biology and Medicine. 49: S73-S74. DOI: 10.1016/J.Freeradbiomed.2010.10.184 |
0.788 |
|
| 2010 |
Cabello CM, Lamore SD, Bair WB, Davis AL, Lesson JL, Wondrak GT. Switching Enemies: The Redox Antimalarial Dihydroartemisinin Targets Human Metastatic Melanoma Cells but not Primary Melanocytes through Induction of NOXA-dependent Apoptosis Free Radical Biology and Medicine. 49: S73. DOI: 10.1016/J.Freeradbiomed.2010.10.183 |
0.813 |
|
| 2009 |
Wondrak GT. Redox-directed cancer therapeutics: molecular mechanisms and opportunities. Antioxidants & Redox Signaling. 11: 3013-69. PMID 19496700 DOI: 10.1089/Ars.2009.2541 |
0.41 |
|
| 2009 |
Cabello CM, Bair WB, Bause AS, Wondrak GT. Antimelanoma activity of the redox dye DCPIP (2,6-dichlorophenolindophenol) is antagonized by NQO1. Biochemical Pharmacology. 78: 344-54. PMID 19394313 DOI: 10.1016/J.Bcp.2009.04.016 |
0.8 |
|
| 2009 |
Cabello CM, Bair WB, Ley S, Lamore SD, Azimian S, Wondrak GT. The experimental chemotherapeutic N6-furfuryladenosine (kinetin-riboside) induces rapid ATP depletion, genotoxic stress, and CDKN1A(p21) upregulation in human cancer cell lines. Biochemical Pharmacology. 77: 1125-38. PMID 19186174 DOI: 10.1016/J.Bcp.2008.12.002 |
0.826 |
|
| 2009 |
Cabello CM, Bair WB, Lamore SD, Ley S, Bause AS, Azimian S, Wondrak GT. The cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growth. Free Radical Biology & Medicine. 46: 220-31. PMID 19000754 DOI: 10.1016/J.Freeradbiomed.2008.10.025 |
0.806 |
|
| 2008 |
Wondrak GT, Cabello CM, Villeneuve NF, Zhang S, Ley S, Li Y, Sun Z, Zhang DD. Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress. Free Radical Biology & Medicine. 45: 385-95. PMID 18482591 DOI: 10.1016/J.Freeradbiomed.2008.04.023 |
0.812 |
|
| 2008 |
Wondrak GT. Reactivity-based drug discovery using vitamin B(6)-derived pharmacophores. Mini Reviews in Medicinal Chemistry. 8: 519-28. PMID 18473939 DOI: 10.2174/138955708784223468 |
0.384 |
|
| 2008 |
Wang XJ, Sun Z, Villeneuve NF, Zhang S, Zhao F, Li Y, Chen W, Yi X, Zheng W, Wondrak GT, Wong PK, Zhang DD. Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2. Carcinogenesis. 29: 1235-43. PMID 18413364 DOI: 10.1093/Carcin/Bgn095 |
0.405 |
|
| 2007 |
Cabello CM, Bair WB, Wondrak GT. Experimental therapeutics: targeting the redox Achilles heel of cancer. Current Opinion in Investigational Drugs (London, England : 2000). 8: 1022-37. PMID 18058573 |
0.758 |
|
| 2007 |
Wondrak GT. NQO1-activated phenothiazinium redox cyclers for the targeted bioreductive induction of cancer cell apoptosis. Free Radical Biology & Medicine. 43: 178-90. PMID 17603928 DOI: 10.1016/J.Freeradbiomed.2007.03.035 |
0.532 |
|
| 2007 |
Wondrak GT. Let the sun shine in: mechanisms and potential for therapeutics in skin photodamage. Current Opinion in Investigational Drugs (London, England : 2000). 8: 390-400. PMID 17520868 |
0.385 |
|
| 2006 |
Wondrak GT, Jacobson MK, Jacobson EL. Endogenous UVA-photosensitizers: mediators of skin photodamage and novel targets for skin photoprotection. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 5: 215-37. PMID 16465308 DOI: 10.1039/B504573H |
0.41 |
|
| 2006 |
Wondrak GT, Jacobson MK, Jacobson EL. Antimelanoma activity of apoptogenic carbonyl scavengers. The Journal of Pharmacology and Experimental Therapeutics. 316: 805-14. PMID 16210394 DOI: 10.1124/Jpet.105.094953 |
0.511 |
|
| 2005 |
Wondrak GT, Jacobson MK, Jacobson EL. Identification of quenchers of photoexcited States as novel agents for skin photoprotection. The Journal of Pharmacology and Experimental Therapeutics. 312: 482-91. PMID 15475591 DOI: 10.1124/Jpet.104.075101 |
0.406 |
|
| 2005 |
Wondrak G, Jacobson M, Jacobson E. An Emerging Molecular Target in Melanoma: Cellular Carbonyl Stress and the Inhibition of Mitochondrial Survival Pathways by Carbonyl Scavenger Agents Current Cancer Therapy Reviews. 1: 271-276. DOI: 10.2174/157339405774574234 |
0.418 |
|
| 2004 |
Wondrak GT, Roberts MJ, Jacobson MK, Jacobson EL. 3-hydroxypyridine chromophores are endogenous sensitizers of photooxidative stress in human skin cells. The Journal of Biological Chemistry. 279: 30009-20. PMID 15133022 DOI: 10.1074/Jbc.M404379200 |
0.494 |
|
| 2003 |
Wondrak GT, Roberts MJ, Cervantes-Laurean D, Jacobson MK, Jacobson EL. Proteins of the extracellular matrix are sensitizers of photo-oxidative stress in human skin cells. The Journal of Investigative Dermatology. 121: 578-86. PMID 12925218 DOI: 10.1046/J.1523-1747.2003.12414.X |
0.446 |
|
| 2003 |
Roberts MJ, Wondrak GT, Laurean DC, Jacobson MK, Jacobson EL. DNA damage by carbonyl stress in human skin cells. Mutation Research. 522: 45-56. PMID 12517411 DOI: 10.1016/S0027-5107(02)00232-4 |
0.453 |
|
| 2002 |
Wondrak GT, Jacobson EL, Jacobson MK. Photosensitization of DNA damage by glycated proteins. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 1: 355-63. PMID 12653475 DOI: 10.1039/B202732C |
0.302 |
|
| 2002 |
Wondrak GT, Roberts MJ, Jacobson MK, Jacobson EL. Photosensitized growth inhibition of cultured human skin cells: mechanism and suppression of oxidative stress from solar irradiation of glycated proteins. The Journal of Investigative Dermatology. 119: 489-98. PMID 12190875 DOI: 10.1046/J.1523-1747.2002.01788.X |
0.421 |
|
| 2002 |
Wondrak GT, Cervantes-Laurean D, Roberts MJ, Qasem JG, Kim M, Jacobson EL, Jacobson MK. Identification of alpha-dicarbonyl scavengers for cellular protection against carbonyl stress. Biochemical Pharmacology. 63: 361-73. PMID 11853687 DOI: 10.1016/S0006-2952(01)00915-7 |
0.399 |
|
| 2001 |
Jacobson EL, Giacomoni PU, Roberts MJ, Wondrak GT, Jacobson MK. Optimizing the energy status of skin cells during solar radiation Journal of Photochemistry and Photobiology B: Biology. 63: 141-147. PMID 11684461 DOI: 10.1016/S1011-1344(01)00211-1 |
0.403 |
|
| 2000 |
Wondrak GT, Cervantes-Laurean D, Jacobson EL, Jacobson MK. Histone carbonylation in vivo and in vitro Biochemical Journal. 351: 769-777. PMID 11042133 DOI: 10.1042/Bj3510769 |
0.367 |
|
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